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Semi-Quantitative Versus Visual Analysis of Adenosine Perfusion Magnetic Resonance Imaging in Intermediate-Grade Coronary Artery Stenosis Using Fractional Flow Reserve as the Reference: A Pilot Study. 以部分血流储备为参考的中等级别冠状动脉狭窄中腺苷灌注磁共振成像的半定量与目视分析:一项初步研究。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2675
Olivier Ghekiere, Jean-Nicolas Dacher, Willem Dewilde, Wilfired Cools, Paul Dendale, Alain Nchimi

Background: To evaluate the diagnostic accuracy of semi-quantitative adenosine perfusion magnetic resonance imaging (MRI) to determine fractional flow reserve (FFR) ≤ 0.80 intermediate-grade coronary stenoses as compared to visual analysis.

Methods: Forty-six patients (mean age 61 ± 9 years; 33 males) with 49 intermediate-grade stenoses (59 ± 7.6%; range, 42-70% minimal diameter reduction) underwent adenosine perfusion MRI and FFR measurement within four months in this retrospective study. MRI was visually assessed by two experienced readers twice with one-year interval, the second time with the knowledge of the diseased artery. The stress subendocardial myocardial enhancement maximal upslope was evaluated distal to the coronary stenosis (=RISK) and divided by the same value in remote myocardium supplied by normal arteries (=REMOTE) to obtain the relative myocardial perfusion index (RMPI).

Results: The average FFR value was 0.84 ± 0.09 and 15/49(31%) intermediate-grade stenoses were FFR ≤ 0.80. The kappa-values for interobserver agreement assessing inducible perfusion defects on visual readings was 0.20 on the first reading and increased to 0.62 with the knowledge of the stenosis location. Consensus readings had a diagnostic accuracy of 82%(40/49) in identifying FFR ≤ 0.80 stenoses on both blinded and unblinded readings with regards to the knowledge of the stenosis location. Meanwhile, stress subendocardial RMPI had higher accuracy (43/49[88%]) than visual readings to predict FFR ≤ 0.80 stenoses, using a cutoff value of 0.84.

Conclusion: By assessing perfusion changes in remote myocardium, semi-quantitative MRI analysis using stress subendocardial RMPI can provide an equal or more accurate alternative to visual analysis in identifying FFR ≤ 0.80 intermediate-grade stenoses. Larger cohorts of patients are required to validate this approach.

背景:评价半定量腺苷灌注磁共振成像(MRI)对血流储备分数(FFR)≤0.80的中度冠状动脉狭窄的诊断准确性。方法:46例患者(平均年龄61±9岁;33例男性),49例中度狭窄(59±7.6%);在这项回顾性研究中,4个月内进行了腺苷灌注MRI和FFR测量。MRI由两位经验丰富的阅读者进行两次视觉评估,每隔一年进行一次,第二次是在了解病变动脉的情况下进行的。评估冠状动脉狭窄远端心肌内膜下应力增强最大上斜率(=RISK),并除以正常动脉供血远端心肌的相同值(= remote),得到相对心肌灌注指数(RMPI)。结果:平均FFR值为0.84±0.09,15/49(31%)中度狭窄FFR≤0.80。在第一次视觉读数中,评估诱导性灌注缺陷的观察者间一致性kappa值为0.20,随着狭窄位置的了解,kappa值增加到0.62。对于狭窄位置的盲法和非盲法,在FFR≤0.80的狭窄中,共识读数的诊断准确率为82%(40/49)。同时,应力性心内膜下RMPI预测FFR≤0.80狭窄的准确度(43/49[88%])高于目视读数,临界值为0.84。结论:通过评估远端心肌灌注变化,采用应力心内膜下RMPI的半定量MRI分析可以提供与视觉分析相同或更准确的替代方法来识别FFR≤0.80的中度狭窄。需要更大的患者队列来验证这种方法。
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引用次数: 0
Splenic Infarct with Polysplenia Syndrome. 脾梗死伴多脾综合征。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2685
Qin Ling Zhu, Wenjun Zhu

A rare case of spontaneous splenic infarction with polysplenia is presented. The diagnosis was made by confirmed by enhanced computed tomography (CT), which showed multiple spleens in the left abdomen and one of the spleen showing low attenuation areas representing infarct. Polysplenia syndrome is a rare entity associated with heterotaxy syndromes. Radiological examinations help the diagnosis by identifying infarcts in the spleen and other abnormal organs in the chest and abdomen. Teaching Point: We report a rare case of polysplenic syndrome with splenic infarction.

本文报告一例罕见的自发性脾梗死合并脾功能亢进。增强CT显示左腹部多个脾脏,其中一个脾脏呈低衰减区,为梗死灶。多脾综合征是一种罕见的与异位综合征相关的疾病。放射检查通过识别脾脏和胸腹其他异常器官的梗死有助于诊断。教学要点:我们报告一例罕见的多脾综合征合并脾梗死。
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引用次数: 1
MRI AI Use Case: Synthetic CT Images for Fracture Evaluation. MRI AI用例:用于骨折评估的合成CT图像。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-22 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2780
Thiebault Saveyn, Lennart Jans, Frederiek Laloo
Teaching Point: Synthetic CT images can improve evaluation of bony lesions on MRI and show potential for fracture evaluation, but validation is needed.
教学点:合成CT图像可以提高MRI对骨病变的评估,显示骨折评估的潜力,但需要验证。
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引用次数: 0
Sinus Disease Grading on Computed Tomography Before and After Modulating Therapy in Adult Patients with Cystic Fibrosis. 成人囊性纤维化患者调节治疗前后鼻窦疾病的ct分级。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-14 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2812
Corrado Tagliati, Stefano Pantano, Giuseppe Lanni, Davide Battista, Matteo Marcucci, Marco Fogante, Giulio Argalia, Enrico Paci, Gabriella Lucidi Pressanti, Mingliang Ying, Pietro Ripani

Objectives: Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy effects on respiratory function, pulmonary exacerbations and quality of life have been well documented. However, CFTR modulator therapy effects on sinus disease have not been so well reported. A previous study reported that ivacaftor improves appearance of sinus disease on Computed Tomography (CT) in cystic fibrosis (CF) patients with G551D mutation. The aim of this study was to evaluate the effect of CFTR modulator therapy in sinus disease using CT scores in a wider CF patient population.

Materials and methods: Forty-eight adult patients with CF underwent at least one CT sinus examination before CFTR modulator therapy (ivacaftor, lumacaftor, ivacaftor/lumacaftor or elexcaftor/tezacaftor/ivacaftor) and one CT sinus examination one year after CFTR modulator therapy initiation. Two radiologists assessed the images in consensus. The Lund-Mackay score (LM score) and the Sheikh-Lind CT sinus disease severity scoring system (SL score) were used. The 22-item SinoNasal Outcome Test (SNOT-22) questionnaire was evaluated before CFTR modulator therapy and one year after CFTR modulator therapy initiation.

Results: CT sinus examination after CFTR modulator therapy showed statistically significant lower mean LM, SL and SNOT-22 scores than CT sinus examination before CFTR modulator therapy (p < 0.001).

Conclusion: Evolution of imaging findings on CT during follow-up closely correlate with improved SNOT-22 score one year after CFTR modulator therapy initiation, indicating that CT may be a useful adjunct during follow-up of CF patients under this treatment as an objective measure of sinonasal disease improvement.

目的:囊性纤维化跨膜传导调节剂(CFTR)治疗对呼吸功能、肺恶化和生活质量的影响已被充分证实。然而,CFTR调节剂治疗鼻窦疾病的效果还没有很好的报道。先前的一项研究报道,ivacaftor可改善G551D突变囊性纤维化(CF)患者的计算机断层扫描(CT)上鼻窦疾病的表现。本研究的目的是在更广泛的CF患者群体中使用CT评分来评估CFTR调节剂治疗窦性疾病的效果。材料和方法:48例成年CF患者在CFTR调节剂治疗前(干扰素、肿瘤因子、干扰素/肿瘤因子或电激器/肿瘤因子/干扰素)至少进行一次CT窦部检查,并在CFTR调节剂治疗开始一年后进行一次CT窦部检查。两位放射科医生一致评估了这些图像。采用Lund-Mackay评分(LM评分)和Sheikh-Lind CT窦性疾病严重程度评分系统(SL评分)。在CFTR调节剂治疗前和CFTR调节剂开始治疗一年后,对22项鼻窦结局测试(SNOT-22)问卷进行评估。结果:CFTR调整剂治疗后CT鼻窦检查LM、SL、SNOT-22平均评分低于CFTR调整剂治疗前CT鼻窦检查,差异有统计学意义(p < 0.001)。结论:随访期间CT影像学表现的变化与CFTR调节剂治疗开始一年后SNOT-22评分的改善密切相关,提示CT可能是CF患者接受CFTR调节剂治疗后随访中有用的辅助手段,可作为鼻窦疾病改善的客观指标。
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引用次数: 4
Atypical Hepatic Hemangioma with Fluid-Fluid Level on CT and MRI: Emphasis on Added Value of Contrast-Enhanced Ultrasound Findings. 不典型肝血管瘤的CT和MRI表现:强调超声增强检查的附加价值。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-09 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2824
Ye Rin Kim, Ji Eun Lee, Min Jung Jung

We present an atypical case of a patient with hepatic hemangiomas showing fluid-fluid levels on computed tomography (CT) and magnetic resonance imaging (MRI). None of the lesions showed contrast enhancement, mimicking complicated hepatic cysts or metastasis with hemorrhagic content. On contrast-enhanced ultrasound the lesions showed peripheral nodular enhancement with complete fill-in on late phases, suggestive of hepatic hemangioma. Teaching point: Contrast-enhanced ultrasound (CE-US) may be useful in diagnosing atypical hepatic hemangioma showing fluid-fluid levels on computed tomography (CT) or magnetic resonance imaging (MRI).

我们提出一个非典型病例的病人与肝血管瘤显示液-液水平在计算机断层扫描(CT)和磁共振成像(MRI)。所有病灶均未见增强,表现为复杂的肝囊肿或转移伴出血。超声造影显示病灶周围结节强化,晚期完全充血,提示肝血管瘤。教学要点:对比增强超声(CE-US)可能有助于诊断非典型肝血管瘤,在计算机断层扫描(CT)或磁共振成像(MRI)上显示液-液水平。
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引用次数: 0
Collapse-Related Bone Changes in Osteonecrotic Femoral Heads at Multidetector CT: Comparison between Femoral Heads with Limited and Advanced Collapse. 坏死股骨头在多探头CT上与塌陷相关的骨改变:有限和晚期塌陷股骨头的比较。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-09 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2735
Charbel Mourad, Souad Acid, Nicolas Michoux, Anthony Awad, Bruno Vande Berg

Aim: To assess the frequency of bone changes in resected osteonecrotic femoral head (ONFH) specimens at multidetector computed tomography (MDCT) and compare their frequencies between ONFH with limited or advanced collapse.

Method: Fourteen ONFH were imaged using MDCT (n = 14) and microcomputed tomography ([µCT]; n = 8). Preoperative staging was performed using radiographs and MRI. Coronal reformats of MDCT images of the specimens were analyzed using the grid overlay method. There were 2,933 grid boxes containing cortical bone and 10,596 containing trabecular bone. Two MSK radiologists assessed in every grid box the presence of interface-related sclerosis, cortical bone interruption, trabecular bone interruption, and trabecular bone resorption. The frequency of grid boxes with bone changes at MDCT was calculated and compared between ONFH with limited (<1.5 mm) or advanced (≥1.5 mm) collapse.

Results: For both readers R1 and R2, there were 1111/10596 (10.5%) and 1362/10596 (12.9%) grid boxes with interface-related bone sclerosis, 557/2933 (19%) and 413/2933 (14.1%) with cortical bone interruption, 796/10596 (7.5%) and 665/10596 (6.3%) with trabecular bone interruption, and 331/10596 (3.1%) and 595/10596 (5.6%) with trabecular bone resorption. The frequency of grid boxes with cortical interruption and trabecular bone resorption was significantly higher in ONFH with advanced than in ONFH with limited collapse. There was no significant difference in frequency of grid boxes with trabecular interruption and interface-related bone sclerosis between ONFH with advanced or limited collapse.

Conclusion: Cortical interruption and trabecular resorption, but not trabecular interruption, were more frequent in osteonecrotic femoral heads with advanced than with limited collapse.

目的:通过多检测器计算机断层扫描(MDCT)评估切除股骨头坏死(ONFH)标本的骨改变频率,并比较ONFH与有限或晚期股骨头塌陷的频率。方法:采用MDCT (n = 14)和微CT(µCT)对14例ONFH进行成像;n = 8)。术前通过x线片和MRI进行分期。采用网格叠加法对样本的MDCT图像进行冠状面重构分析。有2,933个网格盒包含皮质骨,10,596个网格盒包含小梁骨。两名MSK放射科医生在每个网格框中评估界面相关硬化、皮质骨中断、骨小梁中断和骨小梁吸收的存在。计算MDCT上骨改变网格盒的频率,并与ONFH和有限的网格盒进行比较。结果:阅读器R1和R2中,界面相关骨硬化网格盒为1111/10596(10.5%)和1362/10596(12.9%),皮质骨中断网格盒为557/2933(19%)和413/2933(14.1%),小梁骨中断网格盒为796/10596(7.5%)和665/10596(6.3%),小梁骨吸收网格盒为331/10596(3.1%)和595/10596(5.6%)。伴有皮质中断和骨小梁骨吸收的网格盒出现频率在进展性ONFH中明显高于伴有有限塌陷的ONFH。伴有小梁中断和界面相关骨质硬化的网格盒出现频率与晚期或有限塌陷的ONFH无显著差异。结论:晚期股骨头坏死患者比局限性股骨头塌陷患者更常发生骨皮质中断和骨小梁吸收,但未发生骨小梁中断。
{"title":"Collapse-Related Bone Changes in Osteonecrotic Femoral Heads at Multidetector CT: Comparison between Femoral Heads with Limited and Advanced Collapse.","authors":"Charbel Mourad,&nbsp;Souad Acid,&nbsp;Nicolas Michoux,&nbsp;Anthony Awad,&nbsp;Bruno Vande Berg","doi":"10.5334/jbsr.2735","DOIUrl":"https://doi.org/10.5334/jbsr.2735","url":null,"abstract":"<p><strong>Aim: </strong>To assess the frequency of bone changes in resected osteonecrotic femoral head (ONFH) specimens at multidetector computed tomography (MDCT) and compare their frequencies between ONFH with limited or advanced collapse.</p><p><strong>Method: </strong>Fourteen ONFH were imaged using MDCT (n = 14) and microcomputed tomography ([µCT]; n = 8). Preoperative staging was performed using radiographs and MRI. Coronal reformats of MDCT images of the specimens were analyzed using the grid overlay method. There were 2,933 grid boxes containing cortical bone and 10,596 containing trabecular bone. Two MSK radiologists assessed in every grid box the presence of interface-related sclerosis, cortical bone interruption, trabecular bone interruption, and trabecular bone resorption. The frequency of grid boxes with bone changes at MDCT was calculated and compared between ONFH with limited (<1.5 mm) or advanced (≥1.5 mm) collapse.</p><p><strong>Results: </strong>For both readers R1 and R2, there were 1111/10596 (10.5%) and 1362/10596 (12.9%) grid boxes with interface-related bone sclerosis, 557/2933 (19%) and 413/2933 (14.1%) with cortical bone interruption, 796/10596 (7.5%) and 665/10596 (6.3%) with trabecular bone interruption, and 331/10596 (3.1%) and 595/10596 (5.6%) with trabecular bone resorption. The frequency of grid boxes with cortical interruption and trabecular bone resorption was significantly higher in ONFH with advanced than in ONFH with limited collapse. There was no significant difference in frequency of grid boxes with trabecular interruption and interface-related bone sclerosis between ONFH with advanced or limited collapse.</p><p><strong>Conclusion: </strong>Cortical interruption and trabecular resorption, but not trabecular interruption, were more frequent in osteonecrotic femoral heads with advanced than with limited collapse.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":" ","pages":"55"},"PeriodicalIF":2.0,"publicationDate":"2022-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40402563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lung Adenocarcinoma Mimicking a Bilateral Cavitary Pneumonia. 模拟双侧空洞性肺炎的肺腺癌。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-06-08 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2825
Cédric Mahiat, Benoît Colinet, Pierre-Antoine Poncelet

Teaching Point: Failure to recognize unusual radiological presentations of some lung adenocarcinomas can lead to misdiagnosis and/or delay appropriate treatment.

教学要点:不能识别一些肺腺癌的异常影像学表现可能导致误诊和/或延误适当的治疗。
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引用次数: 0
Cecal Volvulus. 盲肠的肠扭结。
IF 2 4区 医学 Q4 Medicine Pub Date : 2022-05-04 eCollection Date: 2022-01-01 DOI: 10.5334/jbsr.2766
Kelly Di Dier, Adelard De Backer, Filip Vanhoenacker

Teaching Point: The coffee bean sign, the whirl sign, and the bird's beak sign are the key findings on abdominal CT of cecal volvulus.

教学点:盲肠扭转的腹部CT主要表现为咖啡豆征、漩涡征、鸟喙征。
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引用次数: 0
Value of Contrast-Enhanced FLAIR Images for the Depiction of Papilledema. 对比增强FLAIR图像对乳头状水肿的描述价值。
IF 2 4区 医学 Q4 Medicine Pub Date : 2021-06-17 DOI: 10.5334/jbsr.2479
Alice Petiot, Thierry Duprez

Teaching Point: Contrast-enhanced FLAIR images have unsurpassed value for the radiological depiction of hypertensive papilledema. FLAIR acquisition should therefore be performed after intravenous contrast, especially in the of work-up of intracranial hypertension and/or tumor.

教学要点:对比增强的FLAIR图像对高血压乳头水肿的影像学描述具有无与伦比的价值。因此,FLAIR采集应在静脉造影后进行,特别是在颅内高压和/或肿瘤的检查中。
{"title":"Value of Contrast-Enhanced FLAIR Images for the Depiction of Papilledema.","authors":"Alice Petiot,&nbsp;Thierry Duprez","doi":"10.5334/jbsr.2479","DOIUrl":"https://doi.org/10.5334/jbsr.2479","url":null,"abstract":"<p><p><b>Teaching Point</b>: Contrast-enhanced FLAIR images have unsurpassed value for the radiological depiction of hypertensive papilledema. FLAIR acquisition should therefore be performed after intravenous contrast, especially in the of work-up of intracranial hypertension and/or tumor.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"38"},"PeriodicalIF":2.0,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39102341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arachnoiditis Ossificans. 骨化蛛网膜炎。
IF 2 4区 医学 Q4 Medicine Pub Date : 2021-06-17 DOI: 10.5334/jbsr.2458
Clara Brou, Marie-Anne Labaisse, Patrice Jissendi Tchofo

This case shows the MRI and CT features of a rare entity, namely arachnoiditis ossificans, which should be recognized in patients with long-standing history of multiple spine surgery.

本病例表现出罕见的骨化性蛛网膜炎的MRI和CT特征,在长期进行多次脊柱手术的患者中应予以认识。
{"title":"Arachnoiditis Ossificans.","authors":"Clara Brou,&nbsp;Marie-Anne Labaisse,&nbsp;Patrice Jissendi Tchofo","doi":"10.5334/jbsr.2458","DOIUrl":"https://doi.org/10.5334/jbsr.2458","url":null,"abstract":"<p><p>This case shows the MRI and CT features of a rare entity, namely arachnoiditis ossificans, which should be recognized in patients with long-standing history of multiple spine surgery.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"37"},"PeriodicalIF":2.0,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39102340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the Belgian Society of Radiology
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