Pub Date : 2017-07-13DOI: 10.12980/JCLM.5.2017J7-2
S. Majekodunmi, E. Olorunsola, Uche Collins Ofiwe, A. Udobre, Ekefre-Abasi Akpan
Stephen Olaribigbe Majekodunmi, Emmanuel Oluwatoyin Olorunsola, Uche Collins Ofiwe, Aniefiok Sunday Udobre, Ekefre Akpan Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, P.M.B. 1017, Uyo, Akwa Ibom State, Nigeria National Agency for Science and Engineering Infrastructure, Centre of Excellence, Nanotechnology and Advanced Materials, Akure, Ondo State, Nigeria Department of Pharmaceutical and Medicinal Chemistry, University of Uyo, P.M.B. 1017, Uyo, Akwa Ibom State, Nigeria Journal of Coastal Life Medicine 2017; 5(7): 321-324
{"title":"Material properties of chitosan from shells of Egeria radiata: Drug delivery considerations","authors":"S. Majekodunmi, E. Olorunsola, Uche Collins Ofiwe, A. Udobre, Ekefre-Abasi Akpan","doi":"10.12980/JCLM.5.2017J7-2","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-2","url":null,"abstract":"Stephen Olaribigbe Majekodunmi, Emmanuel Oluwatoyin Olorunsola, Uche Collins Ofiwe, Aniefiok Sunday Udobre, Ekefre Akpan Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, P.M.B. 1017, Uyo, Akwa Ibom State, Nigeria National Agency for Science and Engineering Infrastructure, Centre of Excellence, Nanotechnology and Advanced Materials, Akure, Ondo State, Nigeria Department of Pharmaceutical and Medicinal Chemistry, University of Uyo, P.M.B. 1017, Uyo, Akwa Ibom State, Nigeria Journal of Coastal Life Medicine 2017; 5(7): 321-324","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"321-324"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45327313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.12980/JCLM.5.2017J7-32
D. Ramu, S. Sigamani, H. Venkatachalam, Panneerselvam Bommannan, Dhandapani Ramamurthy
{"title":"The role of probiotics in the control of bacterial diseases and biodegradation of organic matter in shrimp (Penaeus vannamei) culture ponds of South India","authors":"D. Ramu, S. Sigamani, H. Venkatachalam, Panneerselvam Bommannan, Dhandapani Ramamurthy","doi":"10.12980/JCLM.5.2017J7-32","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-32","url":null,"abstract":"","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"293-298"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45480313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.12980/JCLM.5.2017J7-69
Amira Rekik, H. Ayadi, J. Elloumi
{"title":"Seasonal and spatial distributions of dinoflagellates in relation to environmental factors along the north and south coasts of Sfax (Tunisia, Eastern Mediterranean Sea)","authors":"Amira Rekik, H. Ayadi, J. Elloumi","doi":"10.12980/JCLM.5.2017J7-69","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-69","url":null,"abstract":"","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"299-308"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46232699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.12980/JCLM.5.2017J7-66
Malek Besbes Hlila, Kaouther Majouli, H. Jannet, M. Mastouri, M. Aouni, B. Selmi
*Corresponding author: Malek Besbes Hlila, Laboratoire des Maladies Transmissibles et des Substances Biologiquement Actives, Faculté de Pharmacie, Monastir 5019, Tunisie. Tel: +216 97 66 33 56 E-mail: angelkm2007@yahoo.fr Foundation Project: Supported by the Ministry of High Education and Scientific Research, MHSSR of Tunisia (Grant No. 11/TM06). The journal implements double-blind peer review practiced by specially invited international editorial board members.
*通讯作者：Malek Besbes Hlila，Maladies Transmissions and des Substances Biologiquement Actives实验室，Facultéde Pharmacie，Monastir 5019，突尼斯。电话：+216 97 66 33 56电子邮件：angelkm2007@yahoo.fr基金项目：由突尼斯高等教育和科学研究部资助，突尼斯高等教育与科学研究部（批准号：11/TM06）。该期刊实行双盲同行评审，由特邀国际编委会成员实施。
{"title":"Antioxidant and anti α-glucosidase of luteolin and luteolin 7-O-glucoside isolated from Scabiosa arenaria Forssk","authors":"Malek Besbes Hlila, Kaouther Majouli, H. Jannet, M. Mastouri, M. Aouni, B. Selmi","doi":"10.12980/JCLM.5.2017J7-66","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-66","url":null,"abstract":"*Corresponding author: Malek Besbes Hlila, Laboratoire des Maladies Transmissibles et des Substances Biologiquement Actives, Faculté de Pharmacie, Monastir 5019, Tunisie. Tel: +216 97 66 33 56 E-mail: angelkm2007@yahoo.fr Foundation Project: Supported by the Ministry of High Education and Scientific Research, MHSSR of Tunisia (Grant No. 11/TM06). The journal implements double-blind peer review practiced by specially invited international editorial board members.","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"317-320"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42258237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.12980/JCLM.5.2017J6-282
J. Udobang, J. Okokon, A. Bassey
Interest towards scientific investigation of plants used in traditional medicine to treat diseases such as malaria, fevers and pain has been rekindled and renewed with tremendous vigour. The Ibibio people in Southern Nigeria have for ages been using different plants and their parts to treat malaria and other fevers even in the face of available conventional drugs. The use of Setaria megaphylla (S. megaphylla) has been done without much documentation[1]. S. megaphylla is an erect perennial broad-leafed bristle grass, canelike with very coarse and robust roots mostly found along rivers, areas with plenty of moisture and in tropical and subtropical Africa with high rainfall[2], e.g. Nigeria. In Southern Nigeria, Ibibio Tribe in Akwa Ibom State used it for treatment of malaria, pain, fevers and diabetes[1]. The in vitro[3] and in vivo[1] researches have shown that S. megaphylla leaves have antiplasmodial effects. The results of phytochemical screening revealed the presence of flavonoids, deoxy-sugars, terpenes, saponins, tannins, anthraquinones and cardiac glycosides in the root extract[1]. Data from GCMS studies of n-hexane fraction of the leaves showed that it contained components such as 8,11,14-eicosatrienoic acid (Z,Z,Z), phthalic acid, diisooctyl ester, vitamin E, γ-elemene, Urs-12-ene, bicyclogermacrene, α-muurolene, germacrene-A, and guaiol among others[4]. The cytotoxic, immunomodulatory and antileishmanial activities of the ethanol leaf extract of S. megaphylla have been reported[4]. There is little available information about the activities of S. megaphylla roots. Therefore, the present research aimed to evaluate and provide information on the medicinal potentials of S. ARTICLE INFO ABSTRACT
对传统医学中用于治疗疟疾、发烧和疼痛等疾病的植物进行科学研究的兴趣重新燃起，并以巨大的活力重新焕发。多年来，尼日利亚南部的伊比比奥人一直使用不同的植物及其部分来治疗疟疾和其他发烧，即使面对现有的传统药物。megaphylla (S. megaphylla)的使用文献很少。S. megaphylla是一种直立的多年生阔叶刚毛草，茎状，根粗而粗壮，主要分布在河流沿岸、水分充足的地区以及降雨量大的热带和亚热带非洲，如尼日利亚。在尼日利亚南部，阿夸伊博姆州的伊比奥部落用它来治疗疟疾、疼痛、发烧和糖尿病。体外[3]和体内[1]研究表明，巨葡萄叶具有抗疟原虫作用。植物化学筛选结果显示，根提取物[1]中含有黄酮类、脱氧糖、萜烯类、皂苷类、单宁类、蒽醌类和心苷类化合物。正己烷组分的气相色谱分析表明，正己烷组分中含有8,11,14-二十碳三烯酸(Z,Z,Z)、邻苯二甲酸、二异辛基酯、维生素E、γ-榄香烯、ars -12-烯、双环革烯、α-茂烯、革烯- a、愈创酚等成分[10]。巨葡萄叶乙醇提取物的细胞毒性、免疫调节和抗利什曼原虫活性已被报道[10]。关于巨葡萄球菌根的活性几乎没有可用的信息。因此，本研究旨在对其药用潜力进行评价和提供信息
{"title":"Antiplasmodial and antipyretic effects of ethanol root extract and fractions of Setaria megaphylla (Steud) T. Dur and Schinz (Poaceae)","authors":"J. Udobang, J. Okokon, A. Bassey","doi":"10.12980/JCLM.5.2017J6-282","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J6-282","url":null,"abstract":"Interest towards scientific investigation of plants used in traditional medicine to treat diseases such as malaria, fevers and pain has been rekindled and renewed with tremendous vigour. The Ibibio people in Southern Nigeria have for ages been using different plants and their parts to treat malaria and other fevers even in the face of available conventional drugs. The use of Setaria megaphylla (S. megaphylla) has been done without much documentation[1]. S. megaphylla is an erect perennial broad-leafed bristle grass, canelike with very coarse and robust roots mostly found along rivers, areas with plenty of moisture and in tropical and subtropical Africa with high rainfall[2], e.g. Nigeria. In Southern Nigeria, Ibibio Tribe in Akwa Ibom State used it for treatment of malaria, pain, fevers and diabetes[1]. The in vitro[3] and in vivo[1] researches have shown that S. megaphylla leaves have antiplasmodial effects. The results of phytochemical screening revealed the presence of flavonoids, deoxy-sugars, terpenes, saponins, tannins, anthraquinones and cardiac glycosides in the root extract[1]. Data from GCMS studies of n-hexane fraction of the leaves showed that it contained components such as 8,11,14-eicosatrienoic acid (Z,Z,Z), phthalic acid, diisooctyl ester, vitamin E, γ-elemene, Urs-12-ene, bicyclogermacrene, α-muurolene, germacrene-A, and guaiol among others[4]. The cytotoxic, immunomodulatory and antileishmanial activities of the ethanol leaf extract of S. megaphylla have been reported[4]. There is little available information about the activities of S. megaphylla roots. Therefore, the present research aimed to evaluate and provide information on the medicinal potentials of S. ARTICLE INFO ABSTRACT","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"309-316"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43325014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.12980/JCLM.5.2017J7-86
M. Samad, M. Nahiduzzaman, M. Ashrafuzzaman, M. Rashid, M. Akter
Catfish, Heteropneustes fossilis (Bloch, 1794) (H. fossilis) is an important group of fishes in our country. The stinging catfish (H. fossilis) is commercially important and valuable species in many Asian countries[1]. H. fossilis, commonly known as Shing or Singhi, is a popular catfish in Bangladesh and generally grows in large low land, Oxbow Lake, large water body, swamps and marshes, ditches and floodplains with natural care. It is characterized by an accessory respiratory organ (air breathing organ) which enables it to exist for hours when out of water or in indefinitely oxygen-poor water and even in moist mud[2]. So, this species is very potential in seasonal water bodies of Bangladesh. The species is not only recognized for its delicious taste and ARTICLE INFO ABSTRACT
{"title":"Culture of indigenous catfish Shingi, Heteropneustes fossilis (Bloch, 1794), with available low cost formulated feed in earthen ponds of Bangladesh","authors":"M. Samad, M. Nahiduzzaman, M. Ashrafuzzaman, M. Rashid, M. Akter","doi":"10.12980/JCLM.5.2017J7-86","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-86","url":null,"abstract":"Catfish, Heteropneustes fossilis (Bloch, 1794) (H. fossilis) is an important group of fishes in our country. The stinging catfish (H. fossilis) is commercially important and valuable species in many Asian countries[1]. H. fossilis, commonly known as Shing or Singhi, is a popular catfish in Bangladesh and generally grows in large low land, Oxbow Lake, large water body, swamps and marshes, ditches and floodplains with natural care. It is characterized by an accessory respiratory organ (air breathing organ) which enables it to exist for hours when out of water or in indefinitely oxygen-poor water and even in moist mud[2]. So, this species is very potential in seasonal water bodies of Bangladesh. The species is not only recognized for its delicious taste and ARTICLE INFO ABSTRACT","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"288-292"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41847178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-25DOI: 10.12980/JCLM.5.2017J7-35
R. Sowmiya, G. Balasubramani, P. Deepak, D. Aiswarya, S. Ravikumar, P. Perumal
Characterization and screening of in vitro antimalarial and larvicidal activities of selected seaweeds from southeast coast of India against Plasmodium falciparum and Anopheles stephensi Rajamani Sowmiya, Govindasamy Balasubramani, Paramasivam Deepak, Dilipkumar Aiswarya, Sundaram Ravikumar, Sundaram Prasannakumar, Pachiappan Perumal Department of Biotechnology, School of Biosciences, Periyar University, Periyar Palkalai Nagar, Salem, Tamil Nadu 636 011, India Department of Oceanography and Coastal Area Studies, School of Marine Sciences, Alagappa University, Thondi Campus, Ramanathapuram, Tamil Nadu 623 409, India Journal of Coastal Life Medicine 2017; 5(6): 242-248
{"title":"Characterization and screening of in vitro antimalarial and larvicidal activities of selected seaweeds from southeast coast of India against Plasmodium falciparum and Anopheles stephensi","authors":"R. Sowmiya, G. Balasubramani, P. Deepak, D. Aiswarya, S. Ravikumar, P. Perumal","doi":"10.12980/JCLM.5.2017J7-35","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-35","url":null,"abstract":"Characterization and screening of in vitro antimalarial and larvicidal activities of selected seaweeds from southeast coast of India against Plasmodium falciparum and Anopheles stephensi Rajamani Sowmiya, Govindasamy Balasubramani, Paramasivam Deepak, Dilipkumar Aiswarya, Sundaram Ravikumar, Sundaram Prasannakumar, Pachiappan Perumal Department of Biotechnology, School of Biosciences, Periyar University, Periyar Palkalai Nagar, Salem, Tamil Nadu 636 011, India Department of Oceanography and Coastal Area Studies, School of Marine Sciences, Alagappa University, Thondi Campus, Ramanathapuram, Tamil Nadu 623 409, India Journal of Coastal Life Medicine 2017; 5(6): 242-248","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"242-248"},"PeriodicalIF":0.0,"publicationDate":"2017-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43504305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-25DOI: 10.12980/JCLM.5.2017J7-68
A. Thouri, Hassiba Chahdoura, A. Arem, G. Flamini, A. Jelled, L. Achour
Dipartimento di Scienze Farmaceutiche, Sede di Chimica Bioorganica e Biofarmacia, via Bonanno 33, 56126 Pisa, Italy Centro Interdipartimentale di Ricerca "Nutraceutica e Alimentazione per la Salute" Nutrafood, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy Laboratory of Histology and Cytogenetic and Childhood Disease UR12ES10, Faculty of Medicine, University of Monastir, 5019 Monastir, Tunisia Journal of Coastal Life Medicine 2017; 5(6): 254-260
Scienze Farmaceutice，Sede di Chimica Bioorganica e Biofarmacia，via Bonanno 33，56126 Pisa，意大利Ricerca跨部门中心“Nutraceutica e Alimentazione per la Salute”Nutrafood，比萨大学，via del Borgheto 80，56124 Pisa，Monastir大学医学院意大利组织学和细胞遗传学与儿童疾病实验室UR12ES10，5019 Monastir，《突尼斯海岸生命医学杂志》2017；5（6）：254-260
{"title":"Antioxidant activity, volatile and nonvolatile composition of two Phoenix dactylifera L. by-products","authors":"A. Thouri, Hassiba Chahdoura, A. Arem, G. Flamini, A. Jelled, L. Achour","doi":"10.12980/JCLM.5.2017J7-68","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-68","url":null,"abstract":"Dipartimento di Scienze Farmaceutiche, Sede di Chimica Bioorganica e Biofarmacia, via Bonanno 33, 56126 Pisa, Italy Centro Interdipartimentale di Ricerca \"Nutraceutica e Alimentazione per la Salute\" Nutrafood, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy Laboratory of Histology and Cytogenetic and Childhood Disease UR12ES10, Faculty of Medicine, University of Monastir, 5019 Monastir, Tunisia Journal of Coastal Life Medicine 2017; 5(6): 254-260","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"254-260"},"PeriodicalIF":0.0,"publicationDate":"2017-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46694330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-25DOI: 10.12980/JCLM.5.2017J7-61
F. Bamisaye, A. Sulyman, E. Ajani, A. Muhammed
Reactive oxygen species (ROS) are main free radicals generated as a result of oxidative stress, and these ROS may induce oxidative damage to essential biomolecules[1]. Over-production of ROS is termed as oxidative stress. Oxidative stress represents a disproportion between the systemic manifestation of ROS and a biological system’s ability to readily detoxify the reactive intermediates or to repair the resulting damage[2]. There are various neurodegenerative diseases that can occur as a result of oxidative stress caused by generation of reactive oxygen species. These diseases include cancer, cardiovascular diseases, diabetes, tumors, rheumatoid arthritis and epilepsy[3,4]. Human body system is endowed with endogenous protective antioxidant enzymes such as superoxide dismutase that acts as first line of defense, and catalase that mop-ups free radicals which may be produced[5]. However, if the endogenous protective enzymes fall below normal level or become insufficient, dietary antioxidants are needed to counter the effect of excess free radicals production[6]. A number of synthetic antioxidants such as butylated hydroxyanisole (BHA) and butylhydroxytoluene (BHT) have been shown to be carcinogenic[7,8]. Therefore, it is very necessary to find alternative antioxidants of natural origin which are cheap and safe. It has been reported that consumption of certain plant materials may prevent the risk of degenerative diseases caused by oxidative stress[9]. The protective effect of these plant materials against oxidative damage may be connected to the antioxidant compounds including carotenoids, vitamins, flavonoids and phenolics present in the plant[10]. Therefore, the search for antioxidants of natural origin as well as isolation of these antioxidant active components now become imperative[11-13]. Certain plants have been reported to be of medicinal importance, and the decoctions of local medicinal plants as well as vegetables consumed by people are believed to have a meaningful contribution to human health improvement, in terms ARTICLE INFO ABSTRACT
{"title":"Protective effect of juice extract of mesocarp rind of Citrullus lanatus in carbon tetrachloride-induced oxidative stress in rats","authors":"F. Bamisaye, A. Sulyman, E. Ajani, A. Muhammed","doi":"10.12980/JCLM.5.2017J7-61","DOIUrl":"https://doi.org/10.12980/JCLM.5.2017J7-61","url":null,"abstract":"Reactive oxygen species (ROS) are main free radicals generated as a result of oxidative stress, and these ROS may induce oxidative damage to essential biomolecules[1]. Over-production of ROS is termed as oxidative stress. Oxidative stress represents a disproportion between the systemic manifestation of ROS and a biological system’s ability to readily detoxify the reactive intermediates or to repair the resulting damage[2]. There are various neurodegenerative diseases that can occur as a result of oxidative stress caused by generation of reactive oxygen species. These diseases include cancer, cardiovascular diseases, diabetes, tumors, rheumatoid arthritis and epilepsy[3,4]. Human body system is endowed with endogenous protective antioxidant enzymes such as superoxide dismutase that acts as first line of defense, and catalase that mop-ups free radicals which may be produced[5]. However, if the endogenous protective enzymes fall below normal level or become insufficient, dietary antioxidants are needed to counter the effect of excess free radicals production[6]. A number of synthetic antioxidants such as butylated hydroxyanisole (BHA) and butylhydroxytoluene (BHT) have been shown to be carcinogenic[7,8]. Therefore, it is very necessary to find alternative antioxidants of natural origin which are cheap and safe. It has been reported that consumption of certain plant materials may prevent the risk of degenerative diseases caused by oxidative stress[9]. The protective effect of these plant materials against oxidative damage may be connected to the antioxidant compounds including carotenoids, vitamins, flavonoids and phenolics present in the plant[10]. Therefore, the search for antioxidants of natural origin as well as isolation of these antioxidant active components now become imperative[11-13]. Certain plants have been reported to be of medicinal importance, and the decoctions of local medicinal plants as well as vegetables consumed by people are believed to have a meaningful contribution to human health improvement, in terms ARTICLE INFO ABSTRACT","PeriodicalId":60699,"journal":{"name":"海岸生命医学杂志(英文版)","volume":"5 1","pages":"264-269"},"PeriodicalIF":0.0,"publicationDate":"2017-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42739407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-25DOI: 10.12980/JCLM.5.2017J6-300
V. M. Oliveira, T. Nascimento, C. Assis, R. Bezerra, A. Porto
*Corresponding author: Ana Lúcia Figueiredo Porto, Laboratory of Bioactive Product Technology – LABTECBIO, Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, CEP. 52171-9000 Recife, Pernambuco, Brazil. Tel: + 55 81 33206345 E-mail: analuporto@yahoo.com.br Foundation Project: Supported by the National Council of Technological and Scientific Development (CNPq) (process 141465/2011-5), Foundation for Science and Technology of the State of Pernambuco (FACEPE) (Grant number: BFP-01155.05/14). The journal implements double-blind peer review practiced by specially invited international editorial board members.
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