Pub Date : 2024-05-01Epub Date: 2024-05-20DOI: 10.4236/jct.2024.155020
Guzman Percy
This commentary delves into the evolving landscape of cancer incidence and mortality in Costa Rica, presenting a comprehensive analysis of the data. Key findings reveal a concerning upward trajectory in cancer incidence rates, placing Costa Rica at the forefront within Central America. While prostate cancer and breast cancer dominate, disparities emerge when scrutinizing gender-specific trends. Notably, stomach and cervical cancers show declines, potentially attributed to targeted interventions. However, colorectal and liver cancers witness mortality increases, necessitating strategic responses. Geographical disparities persist across provinces, highlighting the need for equitable healthcare access. In conclusion, this commentary underscores the urgency of addressing the burgeoning cancer burden in Costa Rica, calling for evidence-based interventions and collaborative efforts on a global scale.
{"title":"Comprehensive Analysis of Cancer Incidence and Mortality Trends in Costa Rica: Implications for Public Health.","authors":"Guzman Percy","doi":"10.4236/jct.2024.155020","DOIUrl":"10.4236/jct.2024.155020","url":null,"abstract":"<p><p>This commentary delves into the evolving landscape of cancer incidence and mortality in Costa Rica, presenting a comprehensive analysis of the data. Key findings reveal a concerning upward trajectory in cancer incidence rates, placing Costa Rica at the forefront within Central America. While prostate cancer and breast cancer dominate, disparities emerge when scrutinizing gender-specific trends. Notably, stomach and cervical cancers show declines, potentially attributed to targeted interventions. However, colorectal and liver cancers witness mortality increases, necessitating strategic responses. Geographical disparities persist across provinces, highlighting the need for equitable healthcare access. In conclusion, this commentary underscores the urgency of addressing the burgeoning cancer burden in Costa Rica, calling for evidence-based interventions and collaborative efforts on a global scale.</p>","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"15 5","pages":"219-221"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11234073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manar Muhammed Muhammed, A. Elzawawy, Mohamed F. Abozeid, S. Soliman
{"title":"Pretreatment Neutrophil/Lymphocytes Ratio in Non-Metastatic Colon Cancer as a Prognostic and Predictive Factor: A Retrospective Study","authors":"Manar Muhammed Muhammed, A. Elzawawy, Mohamed F. Abozeid, S. Soliman","doi":"10.4236/jct.2023.141002","DOIUrl":"https://doi.org/10.4236/jct.2023.141002","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70995838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Keita, X. Chen, Shiguan Wang, Yakun Liu, Jing Ma, Traoré Bangaly, Hong Liu
{"title":"Tumor Local Microenvironment Is a Key Factor Affecting the Efficacy of PD-1 Inhibitor in Advanced Cervical Cancer: A Case Report and Literature Review","authors":"M. Keita, X. Chen, Shiguan Wang, Yakun Liu, Jing Ma, Traoré Bangaly, Hong Liu","doi":"10.4236/jct.2023.146025","DOIUrl":"https://doi.org/10.4236/jct.2023.146025","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70996428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Adani-Ife, Mathias Ayivi, Gisèle Agbanouvi, Kouéssan Edoh, Tibéname Kombaté, M. Djibril
{"title":"Nursing Care in Patient with Advanced Cancer: The Experience of the Adult Oncology Unit of Lomé","authors":"A. Adani-Ife, Mathias Ayivi, Gisèle Agbanouvi, Kouéssan Edoh, Tibéname Kombaté, M. Djibril","doi":"10.4236/jct.2023.147026","DOIUrl":"https://doi.org/10.4236/jct.2023.147026","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70996488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Spary, Katie DeLoyde, H. Roberts, F. Martin, Chi Pooi Lee, R. Butler, M. Mason, Geraldine A. Thomas, A. Parry-Jones, R. Adams
Over the last 12 years, the Wales Cancer Biobank (WCB) has consented to more than 2000 patients with colorectal cancer (CRC). From these patients, clinical data has been collected and patients have been followed through their cancer journey. Clinical data from these patients have been analyzed to identify any correlation between disease grade and outcome. In a small cohort, consisting of 407 patients, WCB has performed genetic analysis on patient primary tumor samples, identifying and characterizing mutations in the KRAS, NRAS, BRAF, PIK3CA and TP53 genes. The majority of patients with CRC who were consented to WCB were male with a mean age of 69 years and received surgery as the primary treatment for their disease. Pathology and disease-free survival data confirmed worse prognoses associated with more advanced disease. Heterogeneity within the primary tumor was explored in a subgroup of patients. Analysis of the KRAS and TP53 genes confirmed that more than 40% of CRC patients who were tested, harbored a genetic mutation within these genes in their primary tumor. Due to the limited sample size tested, most mutations did not show significant differences in disease-free survival, however, mutation of the BRAF gene did show a decrease in the disease specific survival, in keeping with the published data. Analysis of the patients diagnosed with
{"title":"Clinical Analysis of the Colorectal Cohort within the Wales Cancer Biobank: A Study of Outcomes and Genetic Screening","authors":"L. Spary, Katie DeLoyde, H. Roberts, F. Martin, Chi Pooi Lee, R. Butler, M. Mason, Geraldine A. Thomas, A. Parry-Jones, R. Adams","doi":"10.4236/jct.2023.147027","DOIUrl":"https://doi.org/10.4236/jct.2023.147027","url":null,"abstract":"Over the last 12 years, the Wales Cancer Biobank (WCB) has consented to more than 2000 patients with colorectal cancer (CRC). From these patients, clinical data has been collected and patients have been followed through their cancer journey. Clinical data from these patients have been analyzed to identify any correlation between disease grade and outcome. In a small cohort, consisting of 407 patients, WCB has performed genetic analysis on patient primary tumor samples, identifying and characterizing mutations in the KRAS, NRAS, BRAF, PIK3CA and TP53 genes. The majority of patients with CRC who were consented to WCB were male with a mean age of 69 years and received surgery as the primary treatment for their disease. Pathology and disease-free survival data confirmed worse prognoses associated with more advanced disease. Heterogeneity within the primary tumor was explored in a subgroup of patients. Analysis of the KRAS and TP53 genes confirmed that more than 40% of CRC patients who were tested, harbored a genetic mutation within these genes in their primary tumor. Due to the limited sample size tested, most mutations did not show significant differences in disease-free survival, however, mutation of the BRAF gene did show a decrease in the disease specific survival, in keeping with the published data. Analysis of the patients diagnosed with","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70996592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Benmessaoud, Hasnae Bouhia, H. Ahmut, S. Majjaoui, H. Kacemi, K. Hassouni, T. Kebdani
{"title":"Evaluation of 3D-CRT and VMAT Radiotherapy Plans for Left Breast with Regional Lymph Nodes Irradiation","authors":"H. Benmessaoud, Hasnae Bouhia, H. Ahmut, S. Majjaoui, H. Kacemi, K. Hassouni, T. Kebdani","doi":"10.4236/jct.2023.148028","DOIUrl":"https://doi.org/10.4236/jct.2023.148028","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70996717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Advances in Metabolomics and Therapeutics for Cancer Cachexia","authors":"Charles Paul Lambert","doi":"10.4236/jct.2023.141004","DOIUrl":"https://doi.org/10.4236/jct.2023.141004","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70995551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Value of Peripheral Blood Markers in Hepatocellular Carcinoma Patients Treated with Anti-PD-1 in Combination with Targeted Therapy","authors":"Shaodong Wang, Chengyou Du","doi":"10.4236/jct.2023.144012","DOIUrl":"https://doi.org/10.4236/jct.2023.144012","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70996376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mame Diarra Samb, F. Mbaye, Mouhamadou Ndiaye, S. Toure, M. Sembéne
{"title":"Bat 26 Microsatellite Instability in Oral Cavity Cancers in Senegal","authors":"Mame Diarra Samb, F. Mbaye, Mouhamadou Ndiaye, S. Toure, M. Sembéne","doi":"10.4236/jct.2023.141003","DOIUrl":"https://doi.org/10.4236/jct.2023.141003","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70995506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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