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[Healing of Critical-Size Bone Defects with Tricalcium Phosphate Hydrogel: Evaluation of Hydrogel as a Scaffold for Stem Cells and BMP-2]. 磷酸三钙水凝胶修复临界尺寸骨缺损:水凝胶作为干细胞和BMP-2支架的评价
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/049
M Korbel, L Novotný, L Jandová, P Šponer
<p><strong>Purpose of the study: </strong>The preclinical study aimed to compare the healing of segmental bone defects treated with biodegradable hyaluronic acid and tricalcium phosphate-based hydrogel with the established autologous spongioplasty. Another aim was to evaluate the hydrogel as a scaffold for osteoinductive growth factor of bone morphogenetic protein-2 (BMP-2) and stem cells.</p><p><strong>Material and methods: </strong>The study was conducted in an in vivo animal model. A standardized rabbit model of a 15 mm long segmental bone defect of left radius was used. A total of 40 animals were divided into 5 groups of 8 individuals. In the KO- (negative control) group, the created defect was left to heal spontaneously. In the KO+ (positive control) group, the defect was filled with morselized bone autograft prepared from the resected segment. In the study group A, the defect was filled with hydrogel based on hyaluronic acid derivative and tricalcium phosphate. In the study group B, the defect was filled with hydrogel based on hyaluronic acid derivative, tricalcium phosphate and bone marrow aspirate. In the study group C, the defect was filled with hydrogel based on hyaluronic acid derivative, tricalcium phosphate, bone marrow aspirate and BMP-2. Healing was assessed using radiographs at 1, 6, and 12 weeks postoperatively and histology specimens were collected at 16 weeks postoperatively.</p><p><strong>Results: </strong>Altogether 35 rabbits survived (KO- 7, KO+ 7, A 7, B 6, C 8) until the end of the study. As concerns the radiographic assessment, the best results were achieved by the groups KO+ and C, where new bone formation across the entire width of the bone defect was clearly seen at 6 and 12 weeks and the osteotomy line was completely healed too. At 12 weeks, complete bone remodelling was observed in all animals in the group KO+, whereas in the group C, bone remodelling was fully completed in 5 animals and partially completed in 3 animals. In terms of histological assessment, however, the best results were achieved by the group C, where the bone defect was completely remodelled into lamellar bone in 7 specimens, while in 1 specimen it healed with bony callus formation. In the group KO+, the defect was healed in 4 specimens by cartilaginous callus with loci of remodelling into bony callus, in 2 specimens the bony callus was predominant with cartilaginous callus areas, and only one defect was completely remodelled into lamellar bone.</p><p><strong>Discussion: </strong>Compared to autografts that manifest osteogenic, osteoinductive and osteoconductive properties, the biodegradable hyaluronic acid and tricalcium phosphate-based hydrogel has osteoconductive properties only. Thus, it was also tested in our study as a scaffold for bone marrow cells and BMP-2 osteoinductive growth factor. Thanks to its semi-liquid properties, the biodegradable hyaluronic acid and tricalcium phosphate-based hydrogel is a promising material for use in 3D printi
研究目的:本临床前研究旨在比较生物可降解透明质酸和磷酸三钙基水凝胶与已建立的自体海绵成形术治疗节段性骨缺损的愈合情况。另一个目的是评估水凝胶作为骨形态发生蛋白-2 (BMP-2)骨诱导生长因子和干细胞的支架。材料与方法:采用活体动物模型。采用标准化兔左桡骨段性骨缺损模型。40只动物被分成5组,每组8只。在KO-(阴性对照)组中,留下的缺损自行愈合。在KO+(阳性对照)组中,用切除节段制备的块状自体骨移植物填充缺损。A组用透明质酸衍生物和磷酸三钙为基础的水凝胶填充缺损。B组采用透明质酸衍生物、磷酸三钙和骨髓抽液为基础的水凝胶填充缺损。C组采用透明质酸衍生物、磷酸三钙、骨髓抽液和BMP-2为基础的水凝胶填充缺损。术后1周、6周和12周采用x线片评估愈合情况,术后16周采集组织学标本。结果:共有35只家兔(KO- 7、KO+ 7、a7、b6、c8)存活至研究结束。在影像学评估方面,KO+组和C组取得了最好的结果,在6周和12周时,可以清楚地看到整个骨缺损宽度的新骨形成,截骨线也完全愈合。12周时,KO+组所有动物骨重建完全,而C组5只动物骨重建完全,3只动物骨重建部分完成。组织学评价方面,C组效果最好,7例骨缺损完全重塑为板层骨,1例骨缺损愈合形成骨痂。在KO+组中,4例骨缺损以软骨骨痂愈合,并有骨痂重塑位点,2例骨痂以软骨骨痂区为主,仅有1例骨缺损完全重塑为板层骨。讨论:与具有成骨、骨诱导和骨导电性的自体移植物相比,可生物降解的透明质酸和磷酸三钙基水凝胶仅具有骨导电性。因此,在我们的研究中也测试了它作为骨髓细胞和BMP-2骨诱导生长因子的支架。由于其半液体的特性,可生物降解的透明质酸和磷酸三钙基水凝胶是一种很有前途的3D打印材料。结论:在体内动物模型的临床前研究证实了可生物降解透明质酸和磷酸三钙基水凝胶对临界尺寸节段性骨缺损愈合的有益作用。水凝胶和BMP-2骨诱导生长因子的充填也能较好地修复这些缺损。骨髓抽吸液与水凝胶混合的益处尚未得到证实。关键词:骨缺损,骨不连,兔,透明质酸,磷酸钙,干细胞,BMP-2,支架,骨愈合,海绵成形术。
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引用次数: 0
[Outcomes of Retrograde Femoral Nail Osteosynthesis of Intraarticular Fractures of the Distal Femur]. [股骨远端关节内骨折逆行股内钉成骨的疗效]。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/044
J Zeman, J Zeman, P Korpa, T Matějka, P Zeman, J Matějka
<p><strong>Purpose of the study: </strong>Intraarticular fractures of the distal femur rank among the most severe musculoskeletal injuries. Various treatment options, such as plate osteosynthesis or retrograde nailing, can be employed. This study aims to evaluate the clinical outcomes and complications of intraarticular distal femoral fractures treated with retrograde femoral nail, with particular emphasis on C3 fractures.</p><p><strong>Material and methods: </strong>Between January 2016 and January 2023, 18 AO/33.C3 fractures were treated with a retrograde femoral nail. Of these, two were classified as 33.C1, eight as 33.C2 and eight as 33.C3. Twelve of the fractures were open. After the initial treatment and stabilizing the patient's overall condition, we proceeded with the definitive osteosynthesis. The first phase involved open reduction and fixation using individual screws to reconstruct the articular surface. The second phase consisted in retrograde nailing with correction of the length, axis and rotation of the femur. The evaluation criteria included: complication rate, number of revisions, knee range of motion, mechanical axis and length of the lower extremity, progression of gonarthrosis, pain level, need of walking support, Lysholm and Tegner Activity Score for functional outcome.</p><p><strong>Results: </strong>Overall, we evaluated the complications and the outcomes of 12 patients (13 fractures). Of these, 8 patients experienced some kind of postoperative complications, primarily insufficient healing or nonunion, which were managed through revision surgery. Plate reosteosynthesis was used in 2 patients who were then excluded from the final clinical evaluation. No cases of deep infection or deep vein thrombosis were reported and no patient required total knee replacement. Seven AO/33.C3 fractures were individually evaluated. The average knee range of motion was nearly 0-93°, maximum flexion was 120°. On average, the lower extremity was 1.6 cm shorter and 7.3° varus to the mechanical axis. Only little progression of gonarthrosis was observed along with low levels of pain. The Lysholm Score ranged between 52 and 84 points (averaging 73.1). The mean Tegner Activity Score was 3.4. All results showed adequate improvement in 33.C2 and 33.C1 groups.</p><p><strong>Discussion: </strong>The retrograde femoral nail demonstrates several advantages over the locking compression plate, particularly in biomechanical aspects. Various clinical studies have reported superior outcomes in terms of healing, complication rate, blood loss and functional outcome. Our study findings align with some of those international studies, particularly in the rate of infectious complications (0%), mean Lysholm Score (79.3 p.) and Tegner Activity Score (4.1). On the other hand, we observed a higher rate of revision surgery (53.8 %), mainly due to evaluating 33.C fractures only. The main advantage of this method lies in complete visualization, leading to better reconstruct
研究目的:股骨远端关节内骨折是最严重的肌肉骨骼损伤之一。可以采用多种治疗方案,如钢板内固定或逆行内钉。本研究旨在评价逆行股内钉治疗股骨远端关节内骨折的临床结果和并发症,特别是C3骨折。材料与方法:2016年1月- 2023年1月,18 AO/33。用逆行股内钉治疗C3骨折。其中,两个被归类为33。C1 8等于33。C2加8等于33。c3。其中12处骨折是开放性的。在初步治疗和稳定患者的整体状况后,我们进行了最终的植骨术。第一阶段包括切开复位和使用单个螺钉固定重建关节面。第二阶段包括逆行内钉,矫正股骨的长度、轴向和旋转。评估标准包括:并发症发生率、翻修次数、膝关节活动范围、机械轴和下肢长度、关节病进展、疼痛程度、行走支持需求、功能结局的Lysholm和Tegner活动评分。结果:总的来说,我们评估了12例患者(13例骨折)的并发症和预后。其中,8例患者出现了某种术后并发症,主要是愈合不足或不愈合,通过翻修手术进行了处理。2例患者采用钢板复位,然后排除在最终临床评估之外。无深度感染或深静脉血栓病例报告,无患者需要全膝关节置换术。七AO / 33。单独评估C3骨折。平均膝关节活动范围接近0-93°,最大屈曲度为120°。下肢平均短1.6 cm,机械轴内翻7.3°。仅观察到关节病的轻微进展以及低水平的疼痛。Lysholm分数在52到84分之间(平均73.1分)。Tegner活动评分平均值为3.4。33例患者均有明显改善。C2和33。C1组。讨论:逆行股内钉与锁定加压钢板相比有几个优点,特别是在生物力学方面。各种临床研究报告了在愈合、并发症发生率、失血和功能结局方面的优越结果。我们的研究结果与一些国际研究结果一致,特别是在感染性并发症发生率(0%)、平均Lysholm评分(79.3 p.)和Tegner活动评分(4.1)方面。另一方面,我们观察到更高的翻修手术率(53.8%),主要是由于仅评估33°c骨折。该方法的主要优点在于完全可视化,可以更好地重建关节面,同时具有优异的髓内钉生物力学性能。结论:股骨远端关节内骨折给治疗带来了重大挑战,并经常导致永久性损伤。主要治疗目标包括实现关节面解剖复位、稳定的骨合成、股骨长度和股骨轴的矫正以及早期康复。我们的研究显示了良好的临床结果,并发症发生率相对较低。患者能够无痛地行走,达到良好的活动范围,回到他们的职业并变得自给自足。此外,没有感染并发症,没有明显的关节病进展。关键词:逆行股内钉,股骨远端关节内骨折,功能结局,并发症发生率。
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引用次数: 0
Evaluation of Depression and Cognitive Status in Geriatric Patients Undergoing Orthopedic Surgery. 老年骨科手术患者抑郁和认知状态的评价。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/048
E Yildirim Safak, A Savci, S N Kuyubaşi

Purpose of the study: Cognitive disorders are common in geriatric surgical patients We conducted a study to evaluate depression and cognitive behavior in geriatric patients undergoing orthopedic surgery.

Material and methods: This descriptive cross-sectional study was conducted at a university hospital in Turkey, involving 262 elderly patients who underwent orthopedic surgeries. Data were collected using The Patient Information Form, Standardized Mini-Mental Test, and Geriatric Depression Scale.

Results: The mean score of the Standardized Mini-Mental Test scale of the patients after surgery was 17.97±4.99, mean score of the Geriatric Depression Scale was 6.20±2.78. The study revealed that 85.1% (n=223) of the participants had cognitive impairment and 69.1% (n=181) depressive symptoms. Additionally, cognitive impairment and depressive symptoms increased as age, pain scores, and length of hospital stay increased. Our research also showed that individuals with a history of falls, visual/hearing impairment, malnutrition, use of assistive devices, dependence on others for daily activities, non-educated or single, individuals are more likely to experience geriatric depression and have a higher of cognitive impairment. Additionally, patients who have had hip arthroplasty, have low hemoglobin levels, or have high ASA scores are more prone to cognitive impairment. Cognitive impairment was more common in patients with higher depression scores.

Conclusions: Considering these findings, it is crucial to identify the cognitive disorders and depressive symptoms during their initial hospitalization to prevent or treat them in geriatric patients. Regular monitoring of geriatric patients in orthopedic clinics for symptoms of cognitive status and depression is recommended, and caregivers should be made aware of this issue.

Key words: geriatric patients, orthopedic procedures, cognitive status, depression.

研究目的:认知障碍在老年外科患者中很常见我们进行了一项研究,以评估接受骨科手术的老年患者的抑郁和认知行为。材料和方法:本描述性横断面研究在土耳其一所大学医院进行,涉及262例接受骨科手术的老年患者。数据采用患者信息表、标准化迷你心理测试和老年抑郁量表收集。结果:术后患者标准化迷你心理测试量表平均得分为17.97±4.99分,老年抑郁量表平均得分为6.20±2.78分。研究显示,85.1% (n=223)的参与者有认知障碍,69.1% (n=181)的参与者有抑郁症状。此外,认知障碍和抑郁症状随着年龄、疼痛评分和住院时间的增加而增加。我们的研究还表明,有跌倒史、视力/听力障碍史、营养不良史、使用辅助设备史、日常活动依赖他人史、未受过教育史或单身史的人更容易患老年抑郁症,认知障碍发生率更高。此外,做过髋关节置换术、血红蛋白水平低或ASA评分高的患者更容易出现认知障碍。认知障碍在抑郁得分较高的患者中更为常见。结论:考虑到这些发现,在老年患者最初住院时识别认知障碍和抑郁症状对于预防或治疗它们至关重要。建议在骨科诊所定期监测老年患者的认知状态和抑郁症状,并使护理人员意识到这一问题。关键词:老年患者;骨科手术;认知状态;
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引用次数: 0
[Bilateral Dorsal Fracture-Dislocation of the Proximal Humerus]. [双侧肱骨近端背侧骨折-脱位]。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/014
R Čellár, D Sokol

Fractures of the proximal humerus constitute approximately 5% of all fractures. Shoulder joint injuries without any external mechanical impact during seizures with the occurrence of spasms occur only sporadically. The occurrence rate is reported in approximately 0.4% of patients. Very rarely they occur in the form of epileptic seizure-induced dorsal fracturedislocation impacting both sides. The case report describes a case of a 48-year-old woman with no treatment for epileptic seizures in her medical history. During the first seizure she sustained a bilateral dorsal fracture-dislocation caused by a muscle spasm, without any other mechanical impact. The fractures were classified as a 3-fragment fracture on the right side and a 4-fragment fracture on the left side. After the patient's admission to the inpatient emergency department, reduction under anaesthesia was attempted. Subsequently, after preparation, open reduction and osteosynthesis using an angularly stable plate were performed as a two-stage surgery. No complications were observed postoperatively Currently, at 3 years after surgeries, the female patient has full mobility of her shoulder joints with no subjective difficulties. Key words: epilepsy, seizure, dorsal fracture-dislocation of the proximal humerus.

肱骨近端骨折约占所有骨折的 5%。癫痫发作时,肩关节在没有任何外部机械性撞击的情况下发生痉挛,这种情况只是偶尔发生。据报道,发生率约为 0.4%。极少数患者会出现癫痫发作诱发的双侧肩背骨折脱位。本病例报告描述了一名 48 岁女性的病例,她的病史中没有接受过癫痫发作治疗。在第一次癫痫发作时,她因肌肉痉挛导致双侧背侧骨折脱位,没有受到任何其他机械性撞击。右侧骨折为三段骨折,左侧骨折为四段骨折。患者被送入急诊住院部后,在麻醉状态下尝试了骨折复位。随后,在准备就绪后,分两步进行了切开复位和使用角度稳定钢板进行骨合成手术。术后未发现任何并发症。目前,该女性患者在术后 3 年肩关节活动自如,无任何主观障碍。关键词:癫痫、癫痫发作、肱骨近端背侧骨折-脱位。
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引用次数: 0
[Gait Analysis in Patients with Adolescent Idiopathic Scoliosis]. [青少年特发性脊柱侧凸患者的步态分析]。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/achot2024/022
J Sklenský, M Švehlík, K Urbášek, P Macková, M Repko

Purpose of the study: The study describes changes in gait parameters (temporal-spatial parameters, kinematic parameters represented by the global Gait Deviation Index) of individuals with Adolescent Idiopathic Scoliosis (AIS) compared to the healthy population. The hypothesis assumed a difference in the observed parameters between the two mentioned groups.

Material and methods: In a retrospective study, the temporal-spatial parameters and Gait Deviation Index (GDI) of a cohort of 45 AIS patients (36 girls and 9 boys with the mean age of 15.2 years, the mean Cobb angle of the thoracic curve of 47.3° and the lumbar curve of 51.8°) were compared to a typically developing population of 12 healthy individuals with no musculoskeletal pathology. The difference of followed-up parameters in patients with AIS compared to normal values was assessed by one-sample Student's T-test at the significance level of p = 0.05.

Results: The gait analysis shows significant deviations in the gait stereotype of patients with AIS compared to the healthy population. Statistically significant differences within temporal-spatial parameters were confirmed for cadence, walking speed, step time, stride time for left leg, step length, stride length and step width. The mean GDI of the cohort reached the value of 91.07 that indicates a slight alteration of gait, however, even this change is statistically significant.

Discussion: In our cohort of patients with AIS, we identified a significantly reduced walking speed (on average 15.4% compared to normal values. At the same time, a reduction in cadence (by an average of 7.5%) and an increase of the stride time (by an average of 12%) were recorded. Our mean GDI values were 91.07, which is consistent with the results reported in the literature for comparable groups of AIS patients.

Conclusions: Our study demonstrated that AIS significantly affects gait stereotype. The differences compared to the group of healthy individuals within temporal-spatial parameters were confirmed for cadence, walking speed, duration and length of step and stride, and step width. The kinematic analysis of gait using the global (GDI) index in patients with AIS demonstrated its slight alteration. A better understanding of the change in movement stereotypes and gait in patients with AIS can bring wider possibilities for individualizing conservative treatment and also can help prevent secondary changes in the locomotor system.

Key words: adolescent idiopathic scoliosis, AIS, gait analysis, Gait Deviation Index, GDI.

研究目的该研究描述了青少年特发性脊柱侧弯症(AIS)患者与健康人群相比步态参数(时间-空间参数、运动学参数,以全球步态偏差指数表示)的变化。材料和方法:在一项回顾性研究中,观察了青少年特发性脊柱侧弯症患者的时间-空间参数和以全局步态偏离指数表示的运动参数:在一项回顾性研究中,将 45 名青少年特发性脊柱侧弯症患者(36 名女孩和 9 名男孩,平均年龄 15.2 岁,胸椎曲线的平均 Cobb 角为 47.3°,腰椎曲线的平均 Cobb 角为 51.8°)的时空参数和步态偏差指数(GDI)与 12 名无肌肉骨骼病变的典型发育健康人群进行了比较。与正常值相比,AIS 患者的随访参数差异通过单样本学生 T 检验进行评估,显著性水平为 p = 0.05:结果:步态分析表明,与健康人群相比,AIS 患者的步态定型存在明显偏差。在步频、行走速度、步幅、左腿跨步时间、步长、步幅和步幅等时空参数上,均存在统计学意义上的显著差异。组群的平均 GDI 值达到 91.07,表明步态略有改变,但即使是这种改变也具有统计学意义:讨论:在我们的 AIS 患者群中,我们发现步行速度明显降低(与正常值相比平均降低 15.4%)。同时,我们还记录到步频降低(平均降低 7.5%)和步幅时间增加(平均增加 12%)。我们的平均 GDI 值为 91.07,这与文献中报道的类似 AIS 患者群体的结果一致:我们的研究表明,AIS 严重影响步态定型。结论:我们的研究表明,AIS 对步态定型有明显影响。与健康人相比,步频、行走速度、步长和步幅以及步幅的时空参数均存在差异。使用全局(GDI)指数对步态进行的运动学分析表明,AIS 患者的步态略有改变。更好地了解AIS患者运动定型和步态的变化可为个体化保守治疗带来更广泛的可能性,也有助于预防运动系统的继发性变化。
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引用次数: 0
A Systematic Review and Meta-Analysis of the Outcomes of Reconstruction with Vascularised vs Non-Vascularised Bone Graft after Surgical Resection of Primary Malignant and Non-Malignant Bone Tumors. 原发性恶性和非恶性骨肿瘤手术切除后血管化骨移植与非血管化骨移植重建效果的系统性回顾和荟萃分析》(A Systematic Review and Meta-Analysis of Reconstruction with Vascularised Bone Graft vs Non-Vascularised Bone Graft after Surgical Resection of Primary Malignant and Non-Malignant Bone Tumors)。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/achot2024/020
R Patel, G McConaghie, M M Khan, W Gibson, R Singh, R Banerjee

Purpose of the study: Vascularised bone grafting (VBG) and non-vascularised bone grafting (NVBG) are crucial biological reconstructive procedures extensively employed in the management of bone tumours. The principal aim of this study is to conduct a comparative analysis of the post-resection outcomes associated with the utilisation of vascularised and non-vascularised bone grafts.

Material and methods: A comprehensive and systematic literature review spanning the years 2013 to 2023 was meticulously executed, utilising prominent online databases including PubMed/Medline, Google Scholar, and Cochrane Library. Inclusion criteria were restricted to comparative articles that specifically addressed outcomes pertaining to defect restoration following bone tumour resection via vascularised and non-vascularised bone grafting techniques. The quality of research methodologies was assessed using the Oxford Quality Scoring System for randomised trials and the Newcastle Ottawa Scale for non-randomised comparative studies. Data analysis was conducted using SPSS version 24. Key outcome measures encompassed the Musculoskeletal Tumour Society Score (MSTS), bone union duration, and the incidence of post-operative complications.

Results: This analysis incorporated four clinical publications, enrolling a total of 178 participants (comprising 92 males and 86 females), with 90 patients subjected to VBG and 88 to NVBG procedures. The primary endpoints of interest encompassed MSTS scores and bone union durations. Although no statistically significant distinction was observed in the complication rates between the two cohorts, it is noteworthy that VBG exhibited a markedly superior bone union rate (P<0.001).

Conclusions: Our systematic evaluation revealed that VBG facilitates expedited bone union, thereby contributing to accelerated patient recovery. Notably, complication rates and functional outcomes were comparable between the VBG and NVBG groups. Moreover, the correlation between bone union duration and functional scores following VBG and NVBG merits further investigation.

Key words: reconstruction techniques, vascularised bone grafting, non-vascularised bone grafting, bone tumor, resection.

研究目的:血管化骨移植(VBG)和非血管化骨移植(NVBG)是骨肿瘤治疗中广泛采用的重要生物重建程序。本研究的主要目的是对与使用血管化骨移植和非血管化骨移植相关的切除术后结果进行比较分析:利用PubMed/Medline、谷歌学术(Google Scholar)和Cochrane图书馆等著名在线数据库,对2013年至2023年期间的文献进行了全面系统的细致回顾。纳入标准仅限于通过血管化和非血管化骨移植技术进行骨肿瘤切除术后缺损修复效果的比较性文章。研究方法的质量采用牛津质量评分系统(Oxford Quality Scoring System)对随机试验进行评估,采用纽卡斯尔渥太华量表(Newcastle Ottawa Scale)对非随机比较研究进行评估。数据分析采用 SPSS 24 版本。主要结果指标包括肌肉骨骼肿瘤协会评分(MSTS)、骨结合持续时间和术后并发症发生率:该分析纳入了四篇临床文献,共有178名参与者(包括92名男性和86名女性),其中90名患者接受了VBG手术,88名患者接受了NVBG手术。主要研究终点包括MSTS评分和骨结合持续时间。虽然两组患者的并发症发生率在统计学上没有明显差异,但值得注意的是,VBG 的骨结合率明显高于 NVBG(PConclusions:我们的系统评估显示,VBG 有助于加速骨结合,从而加快患者的康复。值得注意的是,VBG 组和 NVBG 组的并发症发生率和功能结果相当。此外,VBG 和 NVBG 术后骨结合持续时间和功能评分之间的相关性值得进一步研究。关键词:重建技术、血管化骨移植、非血管化骨移植、骨肿瘤、切除术。
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引用次数: 0
Alternative Surgical Treatment Method for 5th Metacarpal Neck Fractures: Comparison of Clinical Outcomes of Intramedullary and Transverse K-Wire Fixations with Additional Antirotational K-Wire. 第五掌骨颈骨折的替代手术治疗方法:髓内固定和横向 K 线固定与附加抗旋转 K 线的临床疗效比较。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/030
U O Kasman, C Turemis, S Surucu, Ö Korkmaz

Purpose of the study: The purpose of this study was to assess the clinical outcomes and complications associated with intramedullary and transverse K-wire fixations of 5th metacarpal neck fractures.

Material and methods: Patients who were operated for 5th metacarpal neck fractures between 2019 and 2022 were evaluated retrospectively. Regarding the surgical treatment methods, patients were assessed by dividing them into two groups. The first group comprised patients who underwent treatment with an intramedullary K-wire. The second group comprises patients who underwent transverse K-wire fixation.

Results: The average quick DASH score of all patients was 5.6±4.7 in the intramedullary K-wire fixation group and 5.9±5.1 in the transverse K-wire fixation group. An average 5th finger metacarpophalangeal joint extension limitation was 6.2±5.7° in the intramedullary fixation group and 6.1±5.8° in the transverse K-wire group. The mean radiological union time was 4.9±0.7 weeks in the intramedullary fixation group and 5.1±0.7 weeks in the transverse K-wire group. No statistically significant difference was found between the quick DASH scores and degrees of the MCP joint extension limitation ( p=0.785). Intramedullary fixation and transverse K-wire fixations are effective surgical treatment methods for metacarpal neck fractures.

Discussion: It has been reported that the intramedullary fixation method in metacarpal bone fractures is more effective than the fixation methods with cross and transverse K-wire. But our results revealed no difference in clinical outcomes between the two surgical fixation methods.

Conclusions: We observed no statistically significant difference between the two fixation techniques with regard to union, clinical outcomes, or complications.

Key words: intramedullary fixation; metacarpal neck fracture; transverse K-wire fixation.

研究目的本研究旨在评估与第5掌骨颈骨折髓内固定和横向K线固定相关的临床结果和并发症:对2019年至2022年期间因第5掌骨颈骨折接受手术的患者进行回顾性评估。关于手术治疗方法,将患者分为两组进行评估。第一组包括接受髓内K线治疗的患者。第二组包括接受横向K线固定的患者:髓内K线固定组所有患者的平均快速DASH评分为(5.6±4.7)分,横向K线固定组为(5.9±5.1)分。髓内固定组患者第五指掌指关节的平均伸展度为 6.2±5.7°,横向 K 线固定组为 6.1±5.8°。髓内固定组的平均放射学结合时间为4.9±0.7周,横向K线组的平均放射学结合时间为5.1±0.7周。快速DASH评分与MCP关节伸展受限程度之间无统计学差异(P=0.785)。髓内固定和横向K线固定是治疗掌骨颈骨折的有效手术方法:讨论:有报道称,掌骨骨折的髓内固定方法比交叉和横向 K 线固定方法更有效。但我们的研究结果显示,两种手术固定方法的临床疗效没有差异:结论:我们观察到两种固定技术在骨结合、临床疗效和并发症方面没有统计学意义上的差异。
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引用次数: 0
The Impact of Coracoid Tip Orientation on Subscapularis Tear Incidence: an MRI-Based Study. 肩胛下肌撕裂发生率与肩胛尖方向的关系:基于核磁共振成像的研究。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/ACHOT2024/032
H Yaka, M Özer, B Sarikaya, U Kanatli

Purpose of the study: This study investigated the relationship between the position of the tip of the coracoid process (CP) relative to the glenoid with subscapularis (Ssc) tears. We hypothesized that the coracoid tip is more inferior, lateral and posterior in patients with Ssc tear.

Material and methods: This research enrolled 34 isolated Ssc tears and 44 controls. We introduced the axial central glenoid-coracoid angle (acGCA) and sagittal central glenoid-coracoid angle (scGCA) to evaluate the position of the tip of the CP relative to the glenoid center on MRI images. In both groups, acGCA, scGCA on MRI and critical shoulder angle (CSA), glenoid inclination (GI) on true anterior-posterior shoulder radiography were evaluated.

Results: When both groups were compared in terms of acGCA, the acGCA values of the Ssc tear group were significantly higher than the control group (p<0.001). The best cut-off value of acGCA for Ssc tears was 28.3°. acGCA values higher than 28.3° showed 93.3% sensitivity and 93.1% specificity for Ssc tears (likelihood ratio:13.53, AUC: 0.979, 95% CI of AUC: 0.950- 0.999). In terms of acGCA, the power analysis between Ssc tears group and control group was 99.9% between Ssc tears and the control group (effect size d=2.63). When both groups were compared in terms of scGCA, the scGCA values of the Ssc tear group were significantly higher than the control group (p<0.001). The best cut-off value of scGCA for Ssc tears was 41.4°. Scores of scGCA greater than 41.8° showed 80% sensitivity and 89.7% specificity for Ssc tears (likelihood ratio: 7.73, AUC: 0.899 95% CI of AUC: 0.837-0.958). In terms of scGCA, the power analysis between Ssc tear and control group was 99.8% (effect size d=1.23). When both groups were compared in terms of CSA and GI; CSA and GI values in the Ssc tear group were significantly higher (p<0.001 and p<0.012, respectively).

Conclusions: AcGCA values higher than 28.3° indicate that the coracoid tip is located more laterally and posteriorly; scGCA values higher than 41.8° indicate that the coracoid tip is located more inferiorly and these two new indexes are showing that more laterally, posteriorly and inferiorly coracoid tip is related to subscapularis tears.

Key words: coracoid process, subscapularis tear, coracoid morphology, scapula morphology.

研究目的本研究调查了肩胛下肌(Ssc)撕裂时,冠状突(CP)顶端相对于盂的位置之间的关系。我们假设,肩胛下肌撕裂患者的冠状突顶端更靠下,更靠外侧,更靠后:本研究选取了 34 例孤立的肩胛下撕裂患者和 44 例对照组患者。我们采用轴向中央盂-鞍角(acGCA)和矢状中央盂-鞍角(scGCA)来评估 MRI 图像上 CP 顶端相对于盂中心的位置。对两组患者的核磁共振成像上的acGCA、scGCA和肩关节临界角(CSA)、肩关节真前后位X光片上的盂唇倾斜度(GI)进行评估:比较两组的 acGCA,Ssc 撕裂组的 acGCA 值明显高于对照组(p 结论:Ssc 撕裂组的 acGCA 值高于对照组(pAcGCA值高于28.3°表明冠状突尖位于更外侧和更后方;scGCA值高于41.8°表明冠状突尖位于更下方,这两个新指标表明更外侧、更后方和更下方的冠状突尖与肩胛下撕裂有关。
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引用次数: 0
[Arthroscopic Subtalar Distraction Arthrodesis in Post-Traumatic Indications]. [创伤后适应症中的关节镜下跗骨牵引关节固定术]。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/achot2024/002
V Rak, J Šrámek, D Ira, M Krtička

Purpose of the study: This manuscript aims to present the method of arthroscopic assisted subtalar arthrodesis and to evaluate the benefi ts of this surgery on our study population.

Material and methods: In the period from 9/2007 to 1/2020, a total of 33 subtalar arthrodesis were performed in 31 patients aged 19-66 years (mean 48 years, median 50 years). The indication for arthrodesis was subtalar arthritis causing pain and gait disorders, or hindfoot deformities (most commonly after a calcaneus bone fracture). The arthroscopic assisted subtalar arthrodesis was performed with autologous tricortical bone block graft harvesting from the pelvis, supplemented by autologous cancellous bone graft. Stabilization was achieved by cannulated screws inserted in neutral ankle position. Patients in our retrospective study were followed up for a mean of 48 months (range, 24-130 months). The patients were evaluated preoperatively and at 2 years after surgery. The hindfoot angles and height (TCA - talocalcaneal angle, CIA - calcaneal inclination angle, TCH - talocalcaneal height) were evaluated on radiographs, bone union was assessed on radiographs and CT scans. The clinical assessment was performed using the ankle-hindfoot scale (AHS) of AOFAS (AOFAS score).

Results: The preoperative AOFAS score was 35-68 points (mean 52, median 54), the postoperative AOFAS score at 2 years after arthrodesis was 58-94 points (mean 82, median 82). Both the mean and median values of AOFAS score showed a signifi - cant progress from the poor result to the good and excellent result. After 2 years the TCA value decreased in 18 patients (56%) by no more than 3°. The CIA decrease observed in 21 patients (64%) was by 1° on average. The TCH decrease of 1-5 mm after 2 years since the surgery was seen in 16 patients. In 2 patients incomplete healing of arthrodesis was observed, manifested as a clinically asymptomatic non-union. No deep infection was reported.

Discussion: In agreement with the current literature, the arthroscopic subtalar arthrodesis has been confi rmed to be a safe method for the management of consequences of hindfoot fractures, with minimum complications and leading to accelerated bone fusion. Differences can be found in the approach, position, use of cancellous bone graft and surgical techniques. In recent years, prone position, posterior approaches, use of cancellous bone graft, distraction and fi xation with 2-3 screws divergently inserted into the bone prevail. The degree of healing of the bone fusion is generally an important factor. In our study population, non-healing was recorded in 2 patients, namely in the form of a clinically silent non-union. Neurological or early complications and/or osteosynthesis material failure occurred in up to a maximum of 10% of cases. The conclusive results of minimally invasive arthrodesis based on the AOFAS score have been confi rmed by us as w

研究目的本手稿旨在介绍关节镜辅助下踝关节置换术的方法,并评估该手术对我们研究人群的益处:在2007年9月至2020年1月期间,共为31名年龄在19-66岁(平均48岁,中位数50岁)的患者实施了33例踝关节置换术。关节置换术的适应症为引起疼痛和步态障碍的踝关节炎或后足畸形(最常见于小方骨骨折后)。关节镜辅助下的距骨关节置换术采用从骨盆采集的自体三皮质骨块移植,辅以自体松质骨移植。在踝关节中立位插入插管螺钉实现稳定。我们的回顾性研究对患者进行了平均 48 个月(24-130 个月)的随访。术前和术后两年对患者进行了评估。通过X光片评估后足角度和高度(TCA - 距骨髁角,CIA - 小关节倾斜角,TCH - 距骨髁高度),通过X光片和CT扫描评估骨结合情况。临床评估采用 AOFAS 的踝-后足量表(AHS)(AOFAS 评分):术前 AOFAS 评分为 35-68 分(平均 52 分,中位数 54 分),关节置换术后 2 年的 AOFAS 评分为 58-94 分(平均 82 分,中位数 82 分)。AOFAS 评分的平均值和中位值都显示出从效果差到效果好和效果优的明显进步。2 年后,18 名患者(56%)的 TCA 值下降不超过 3°。21 名患者(64%)的 CIA 值平均下降了 1°。手术 2 年后,16 名患者的 TCH 值下降了 1-5 mm。有 2 例患者的关节连接处未完全愈合,表现为临床无症状的不愈合。没有深部感染的报道:讨论:与目前的文献一致,关节镜下足底关节置换术被认为是治疗后足骨折后遗症的安全方法,并发症少,可加速骨融合。不同的方法、体位、松质骨移植的使用以及手术技巧都存在差异。近年来,以俯卧位、后入路、使用松质骨移植、牵引和用 2-3 颗螺钉分叉插入骨内进行固定为主。骨融合的愈合程度通常是一个重要因素。在我们的研究对象中,有 2 例患者出现了不愈合,即临床上无症状的不愈合。神经系统或早期并发症和/或骨合成材料失效的病例最多不超过 10%。根据AOFAS评分进行微创关节置换术的最终结果已由我们和大多数作者确认:我们的研究证实,关节镜辅助下的踝关节置换术是一种成功、可靠、安全的微创方法,并发症极少,可获得稳定的踝关节置换效果。
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引用次数: 0
[Total Hip Arthroplasty Using the AMIS Method: Surgical Technique, Suitability of This Method for Obese Patients, Evaluation of the Study Population]. [使用 AMIS 方法进行全髋关节置换术:手术技术、该方法对肥胖患者的适用性、对研究人群的评估]。
IF 0.4 4区 医学 Q4 ORTHOPEDICS Pub Date : 2024-01-01 DOI: 10.55095/achot2024/008
P Palásek, P Mašát, V Řeháček

Purpose of the study: This manuscript aims to introduce our surgical technique, with an emphasis on the latest recommendations. The AMIS technique is discussed in more detail in patients with Class II and Class III obesity. We seek to prove the premise claiming that the anteversion and inclination values observed in this group of patients do not differ signifi cantly from those observed in patients with the recommended BMI index. We will also compare the risk of neurovascular bundle injury and postoperative complication rate regarding the surgical wound.

Material and methods: Patients who underwent surgery using the AMIS method in the period between 1/2020 and 4/2023 were assessed retrospectively. The study included 1150 implantations. The entire study population was assessed for neurovascular bundle injury and surgical wound healing complications. For this purpose, the patients were divided into two groups based on the BMI, namely BMI < 35 kg/m2 (n=1042) and BMI > 35 kg/m2 (n=108). In patients with the BMI ≤ 25 kg/m2 (n=280) and BMI ≥ 35 kg/m2 (n=108), the inclination and anteversion values were compared. Standard centered AP view X-rays of their operated joints were assessed. The Liaw's method was used to calculate the anteversion and inclination.

Results: In group one of patients with BMI ≤ 25 kg/m2 (208 women and 72 men), the arithmetic mean of acetabular anteversion was 25.4° (median 25°) and inclination was 38.3° (median 38°). In group two, which consisted of patients with BMI ≥ 35 kg/m2 (59 women and 49 men), the total arithmetic mean of acetabular anteversion was 25.1° (median 25) and inclination was 37.6° (median 37.5°). The anteversion and inclination were assessed using the Mann-Whitney test for equality of medians. The value of 0.05 was chosen as the level of signifi cance. The resulting p-value was 0.5359 in anteversion and 0.3763 in inclination. Since the p-value of both anteversion and inclination was greater than the chosen level of signifi cance, their medians have not been confi rmed to differ signifi cantly. A total of 6 cases of femoral nerve injury was reported, i.e. 0.5% out of 1150. Therefore, the risk of injury was 0.4% in the group with BMI < 35 kg/m2 (n=1042). On the contrary, in the group of patients with BMI > 35 kg/m2 (n=108), the risk was 2%. No injury to femoral artery was reported. The surgical wound healing complications were seen in a total of 87 cases (7.6%). In the group with BMI < 35 kg/m2 , healing complications of the surgical wound were observed in 7.4% of cases, with the need for revision surgery in 7 patients. In the group with BMI > 35 kg/ m2 , healing complications occurred in 13% of patients and wound revision was necessary in 4 cases.

Discussion: Our results are consistent with those in the published studies that also show no signifi cant difference in anteversion and inclination of components in the compared grou

研究目的本手稿旨在介绍我们的手术技术,重点是最新的建议。我们将更详细地讨论 AMIS 技术在 II 级和 III 级肥胖症患者中的应用。我们试图证明这样一个前提,即在这类患者身上观察到的前内翻和倾斜值与在具有推荐 BMI 指数的患者身上观察到的前内翻和倾斜值没有明显差异。我们还将比较神经血管束损伤的风险和手术伤口的术后并发症发生率:对 2020 年 1 月 1 日至 2023 年 4 月 4 日期间使用 AMIS 方法进行手术的患者进行回顾性评估。研究包括 1150 例植入手术。对所有研究对象的神经血管束损伤和手术伤口愈合并发症进行了评估。为此,根据体重指数将患者分为两组,即体重指数< 35 kg/m2(1042人)和体重指数> 35 kg/m2(108人)。在 BMI ≤ 25 kg/m2(n=280)和 BMI ≥ 35 kg/m2(n=108)的患者中,对倾斜度和前内翻值进行比较。对其手术关节的标准中心 AP 角 X 光片进行评估。结果:在第一组中,体重指数≤25 kg/m2的患者(女性208人,男性72人)的髋臼前倾角算术平均值为25.4°(中位数为25°),倾斜度为38.3°(中位数为38°)。第二组包括体重指数≥ 35 kg/m2 的患者(59 名女性和 49 名男性),髋臼内翻的总算术平均值为 25.1°(中位数为 25°),倾斜度为 37.6°(中位数为 37.5°)。采用 Mann-Whitney 中位数相等检验对髋臼前倾角和倾斜度进行评估。选择 0.05 作为显著性水平。结果前倾角的 p 值为 0.5359,后倾角的 p 值为 0.3763。由于前倾角和后倾角的 p 值均大于所选的显著性水平,因此它们的中位数不存在显著性差异。共报告了 6 例股神经损伤,即 1150 例中的 0.5%。因此,体重指数小于 35 kg/m2 组(n=1042)的损伤风险为 0.4%。相反,在体重指数大于 35 kg/m2 的患者组(108 人)中,受伤风险为 2%。没有股动脉损伤的报道。手术伤口愈合并发症共有 87 例(7.6%)。在体重指数小于 35 kg/m2 的组别中,7.4% 的病例出现了手术伤口愈合并发症,其中 7 名患者需要进行翻修手术。在体重指数大于 35 千克/平方米的人群中,13% 的患者出现了伤口愈合并发症,4 例患者需要进行伤口翻修:讨论:我们的研究结果与已发表的研究结果一致,这些研究结果也显示,肥胖患者组在组件的前倾角和后倾角方面没有明显差异。我们也同意其他作者的观点,即这些患者的手术伤口愈合并发症发生率更高。本研究人群中发生神经血管束损伤的风险并不比标准人群高:我们的研究结果表明,这种方法也适用于体重指数(BMI)较高的患者,无需担心植入的组件位置不正或神经血管损伤的风险较高。不过,选择这种方法时应考虑到手术伤口愈合的潜在高风险。通过适当的手术技巧,AMIS 是一种安全的方法,我们认为它是首选,尤其是对于肥胖患者:AMIS、内翻、倾斜、髋关节、肥胖、体重指数、植入、全关节置换。
{"title":"[Total Hip Arthroplasty Using the AMIS Method: Surgical Technique, Suitability of This Method for Obese Patients, Evaluation of the Study Population].","authors":"P Palásek, P Mašát, V Řeháček","doi":"10.55095/achot2024/008","DOIUrl":"10.55095/achot2024/008","url":null,"abstract":"<p><strong>Purpose of the study: </strong>This manuscript aims to introduce our surgical technique, with an emphasis on the latest recommendations. The AMIS technique is discussed in more detail in patients with Class II and Class III obesity. We seek to prove the premise claiming that the anteversion and inclination values observed in this group of patients do not differ signifi cantly from those observed in patients with the recommended BMI index. We will also compare the risk of neurovascular bundle injury and postoperative complication rate regarding the surgical wound.</p><p><strong>Material and methods: </strong>Patients who underwent surgery using the AMIS method in the period between 1/2020 and 4/2023 were assessed retrospectively. The study included 1150 implantations. The entire study population was assessed for neurovascular bundle injury and surgical wound healing complications. For this purpose, the patients were divided into two groups based on the BMI, namely BMI < 35 kg/m2 (n=1042) and BMI > 35 kg/m2 (n=108). In patients with the BMI ≤ 25 kg/m2 (n=280) and BMI ≥ 35 kg/m2 (n=108), the inclination and anteversion values were compared. Standard centered AP view X-rays of their operated joints were assessed. The Liaw's method was used to calculate the anteversion and inclination.</p><p><strong>Results: </strong>In group one of patients with BMI ≤ 25 kg/m2 (208 women and 72 men), the arithmetic mean of acetabular anteversion was 25.4° (median 25°) and inclination was 38.3° (median 38°). In group two, which consisted of patients with BMI ≥ 35 kg/m2 (59 women and 49 men), the total arithmetic mean of acetabular anteversion was 25.1° (median 25) and inclination was 37.6° (median 37.5°). The anteversion and inclination were assessed using the Mann-Whitney test for equality of medians. The value of 0.05 was chosen as the level of signifi cance. The resulting p-value was 0.5359 in anteversion and 0.3763 in inclination. Since the p-value of both anteversion and inclination was greater than the chosen level of signifi cance, their medians have not been confi rmed to differ signifi cantly. A total of 6 cases of femoral nerve injury was reported, i.e. 0.5% out of 1150. Therefore, the risk of injury was 0.4% in the group with BMI < 35 kg/m2 (n=1042). On the contrary, in the group of patients with BMI > 35 kg/m2 (n=108), the risk was 2%. No injury to femoral artery was reported. The surgical wound healing complications were seen in a total of 87 cases (7.6%). In the group with BMI < 35 kg/m2 , healing complications of the surgical wound were observed in 7.4% of cases, with the need for revision surgery in 7 patients. In the group with BMI > 35 kg/ m2 , healing complications occurred in 13% of patients and wound revision was necessary in 4 cases.</p><p><strong>Discussion: </strong>Our results are consistent with those in the published studies that also show no signifi cant difference in anteversion and inclination of components in the compared grou","PeriodicalId":6980,"journal":{"name":"Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca","volume":"91 1","pages":"24-33"},"PeriodicalIF":0.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140048474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
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