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Basic medical sciences should be mainly taught by the clinicians for a tightly integration of basic and clinical sciences in medical education. 基础医学应由临床医生主讲,实现医学教育中基础科学与临床科学的紧密结合。
Pub Date : 2022-10-29 DOI: 10.30565/medalanya.1159175
S. Oktar
Medical education today faces many problems. But the most serious problem is the inability to integrate basic and clinical sciences. For this reason, students alienate from basic sciences and also clinicians are leaving sciences to basic scientists every day. The basic medical sciences learned in the preclinical term are remembered less by the students and cannot be sufficiently associated with clinical reality. Because a basic scientific knowledge learned without clinical framework is a low-value data that the student does not know how to use. Therefore, all reform initiatives in the medical education curriculum stick to the obstacle of basic sciences. Now is the time to take bold steps. The first step should be to removed the preclinical term from medical education. Medical education should only consist of clinical education term. This will gain the student and clinician a lot more time for clinical training. The second step should be to take basic sciences education from basic scientists and place it under the responsibility of clinicians. Clinician can decide much better how much of a basic sciences knowledge is clinically relevant. As a component of clinical education, it is best for the students to internalize the basic sciences during classroom, bedside and other clinical practices under the clinician's authority. Thus, students may be graduated as academic clinicians who have internalized the basic sciences and integrated the basic sciences with the clinical reality.
今天的医学教育面临着许多问题。但最严重的问题是无法整合基础科学和临床科学。因此,学生们每天都在疏远基础科学,医生们也每天都在把科学留给基础科学家。在临床前期学习的基础医学知识很少被学生记住,不能与临床实际充分联系起来。因为没有临床框架的基础科学知识是学生不知道如何使用的低价值数据。因此,医学教育课程改革的所有举措都坚持以基础科学为障碍。现在是采取大胆措施的时候了。第一步应该从医学教育中去除临床前术语。医学教育应只由临床教育学期组成。这将使学生和临床医生有更多的时间进行临床培训。第二步是将基础科学教育从基础科学家手中剥离出来,交由临床医生负责。临床医生可以更好地决定基础科学知识在多大程度上与临床相关。作为临床教育的一个组成部分,在临床医生的权威下,学生在课堂、床边和其他临床实践中内化基础科学是最好的。因此,学生毕业后可能会成为内化基础科学并将基础科学与临床实际相结合的学术临床医生。
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引用次数: 1
Effect of miRs-17/20 on Vasospasm in Subarachnoid Hemorrhage Model of Rats mir -17/20对大鼠蛛网膜下腔出血模型血管痉挛的影响
Pub Date : 2022-10-29 DOI: 10.30565/medalanya.1152279
Başak Büyük, Ü. A. Malçok
Aim: To investigate the effects of melatonin and miRNA-17/20 administration on vasospasm and vascular damage on the bacillary artery in the Subarachnoid hemorrhage (SAH) model of rats. Methods: Rats were divided into 6 groups: Sham,SAH,SAH+NegmiRNA,SAH+MEL,SAH-miRs-17/20 group,SAH+MEL+miRs-17/20.For creating the SAH model the skin was cut with a vertical incision in the anterior region of the head.120 µL of fresh non-heparinized autologous arterial blood collected from the tail artery was injected into the prechiasmatic cistern under aseptic conditions. All steps in the Sham were the same as in the SAH group, except for blood injection. In the SAH+NegmiRs-17/20, miRs-17/20 miRNA Mimic-Negative Control#1 was administered 1 hour after SAH operation. In the SAH+MEL,10 mg/kg melatonin was administered intraperitoneally 1 hour after the SAH operation. In the SAH-miRs-17/20,mimic-miR-17 and mimic-miR-20 were given intranasally 1 hour after the SAH operation.In the SAH+MEL+miRs-17/20,intranasal mimic-miR-17 and intraperitoneal melatonin were administered 1 hour after the SAH operation. Brain samples, including the bacillary artery, were taken and subjected to routine tissue processing procedures. Vessel samples were evaluated and graded in histological sections stained with the H-E method in terms of vasospasm, edema in the tunica media, and folding of the lamina elastica interna. Results: The co-administration of melatonin and miRs-17/20 reduced the vasospasm and edema formation in the vessel wall. It has also been demonstrated that the application of miRs-17/20 after SAH alone reduces the development of edema in the vessel wall and folding of the internasal lamina elastica due to vasospasm. Conclusion:It has been shown that miRs-17/20 can reduce vasospasm in the vessel wall and prevent vessel damage by reducing edema.
目的:探讨褪黑素和miRNA-17/20给药对大鼠蛛网膜下腔出血(SAH)模型中细菌动脉血管痉挛和血管损伤的影响。方法:将大鼠分为Sham组、SAH组、SAH+NegmiRNA组、SAH+MEL组、SAH- mir -17/20组、SAH+MEL+ mir -17/20组。为了创建SAH模型,在头部前区用垂直切口切开皮肤。取尾动脉新鲜非肝素化自体动脉血120µL,无菌条件下注入交叉前池。除注射血液外,Sham组的所有步骤与SAH组相同。在SAH+ negmir -17/20中,在SAH手术后1小时给予mir -17/20 miRNA模拟阴性对照#1。在SAH+MEL中,SAH手术后1小时腹腔注射10 mg/kg褪黑素。在SAH- mir -17/20中,在SAH手术后1小时鼻内给予mimi - mir -17和mimi - mir -20。在SAH+MEL+ mir -17/20组中,SAH手术后1小时鼻内给予mimic-miR-17和腹腔内给予褪黑激素。取脑样本,包括杆菌动脉,并进行常规组织处理程序。血管样本在H-E染色的组织学切片上根据血管痉挛、中膜水肿和内弹性板折叠进行评估和分级。结果:褪黑素与mir -17/20联合用药可减轻血管痉挛和血管壁水肿的形成。也有研究表明,仅在SAH后应用mir -17/20可减少血管壁水肿的发展和血管痉挛引起的鼻间弹性板折叠。结论:研究表明miRs-17/20可减轻血管壁的血管痉挛,通过减轻水肿来预防血管损伤。
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引用次数: 0
The evaluation of vaccination status and the factors affecting vaccination in cancer patients 肿瘤患者疫苗接种状况及影响因素评价
Pub Date : 2022-10-29 DOI: 10.30565/medalanya.1094182
Muslih Ürün, I. Beypınar, S. E. Davarcı, H. Demir, M. Baykara
Background and aim: Coronavirus disease 2019 (COVID-19) pandemic increased the mortality of cancer patients by causing direct infection or collateral damage to the healthcare system. After the development of effective vaccines against COVID-19 infection, mortality rates declined. In this study, we try to investigate the vaccination among cancer patients. Material and Methods: A survey was applied to patients with cancer in order to investigate the attitudes towards vaccination and the factors effecting vaccination in two medical oncology centers in Turkey. Results: 271 patients were included in the study. No difference was observed in the attitudes of patients towards vaccination according to cancer type. 83% of the patients were vaccinated against COVID-19. In 75% of the study population, vaccine was administered in the earliest available time. Receiving chemotherapy was the most significant reason to avoid vaccination among the study group (p=0,002). There was no significant difference in terms of treatment type for COVID-19 between patients with or without adequate vaccination. The most negative factor affecting vaccination was active chemotherapy treatment. Social relations and traditional media were the most positive factors for vaccination. Discussion: Vaccination is of vital importance for patients who are treated or on remission. Even if patients are to receive chemotherapy, they should be informed about vaccination and should be encouraged for vaccination.
背景与目的:2019冠状病毒病(COVID-19)大流行通过对医疗保健系统造成直接感染或附带损害,增加了癌症患者的死亡率。在研发出针对COVID-19感染的有效疫苗后,死亡率有所下降。在这项研究中,我们试图调查癌症患者的疫苗接种情况。材料和方法:对土耳其两家肿瘤医学中心的癌症患者进行调查,以调查他们对疫苗接种的态度和影响疫苗接种的因素。结果:271例患者纳入研究。不同癌症类型患者对疫苗接种的态度无差异。83%的患者接种了COVID-19疫苗。在75%的研究人群中,疫苗在最早可用的时间内接种。接受化疗是研究组避免接种疫苗的最重要原因(p= 0.002)。接种疫苗或未接种疫苗的患者在COVID-19治疗类型方面无显著差异。影响疫苗接种的最不利因素是积极的化疗。社会关系和传统媒体是接种疫苗最积极的因素。讨论:疫苗接种是至关重要的病人谁是治疗或缓解。即使病人接受化疗,也应告知他们接种疫苗,并应鼓励他们接种疫苗。
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引用次数: 0
The Patient Application to the Outpatient Plastic Surgery Clinic and Management of Treatments During the Covid-19 Pandemic: Comparison of Prepandemic and Postpandemic Periods 新冠肺炎大流行期间门诊整形门诊患者申请及治疗管理:大流行前与大流行后的比较
Pub Date : 2022-10-28 DOI: 10.30565/medalanya.1074247
Seçkin AYDIN SAVAŞ
Objective: The aim of this study is to show the differences about patient profile and treatment selections in outpatient plastic surgery clinic by comparing the pre-pandemic and the pandemic period for one year processes. Methods: The patients who applied to outpatient clinic of plastic surgery during the pre-pandemic and pandemic periods were included in the study. The data related to demographic characteristics, reasons for application of outpatient plastic surgery clinic, pre-diagnosis, and treatment modalities -outpatient or inpatient- were collected retrospectively. Results: It was observed that there was a significant numerical difference in the number of applications of the patients between the pre-pandemic and the pandemic periods. The application rate of females decreased, while the rate of males increased during the pandemic period. When we examined the application rates in the age groups, the patient application rates in the 12-18, 18-25, and 25-40 age groups increased. In the other age groups, the patient application rates were decreased (p
目的:本研究的目的是通过比较大流行前和大流行期一年的过程来显示门诊整形诊所患者概况和治疗选择的差异。方法:选取大流行前和大流行期间在门诊整形外科就诊的患者为研究对象。回顾性收集与人口统计学特征、门诊整形外科门诊应用原因、预诊断和治疗方式(门诊或住院)相关的数据。结果:观察到在大流行前和大流行期间,患者的申请人数有显著的数字差异。在大流行期间,女性的应用率下降,而男性的应用率上升。当我们检查各年龄组的应用率时,12-18岁、18-25岁和25-40岁年龄组的应用率有所增加。在其他年龄组,患者的应用率下降(p
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引用次数: 0
Effects of Nasal Pathologies in Paediatric Epistaxis 小儿鼻出血的鼻病理影响
Pub Date : 2022-10-28 DOI: 10.30565/medalanya.1127833
Oğuzhan Dikici, Osman Durgut
Objectives: The aim of this study was to investigate the effects of nasal pathologies in paediatric patients with recurrent epistaxis. Methods: A total of 100 (61 boys, 39 girls) patients aged 2–17 years (mean age: 8.9 ± 3.6 years) were included in this study. Anterior rhinoscopy and flexible nasal endoscopy were used to examine all the patients. The epistaxis duration, treatment in active epistaxis by parents, medical history, medical treatment and interventions were recorded. The location of the epistaxis site, nasal mucosa type, the presence of nasal vestibulitis, nasal septum deviation location and type, adenoid size and the degree of inferior turbinate hypertrophy were recorded. Results: The deviation was present in 31 (62%) patients with recurrent epistaxis and in 14 (28%) patients without epistaxis. The presence of deviation was significantly higher in the epistaxis group than control group (p = 0.001). The nasal mucosa type was friable mucosa in 37 (74%) patients, vascularised mucosa in 11 (22%) patients and friable – vascularised mucosa in 2 (4%) patients in recurrent epistaxis group. A significant relationship was detected between nasal mucosa type and age, the presence of the deviation, deviation location, Mladina type in epistaxis group (p = 0.005, p = 0.004, p = 0.008, p = 0.015). Conclusion: Nasal septum deviation, inferior turbinate hypertrophy and nasal mucosa type are associated with paediatric recurrent epistaxis.
目的:本研究的目的是探讨鼻腔病理对儿童复发性鼻出血的影响。方法:共纳入100例(男61例,女39例)患者,年龄2 ~ 17岁,平均年龄8.9±3.6岁。所有患者均采用鼻前镜及鼻软内镜检查。记录患儿鼻出血持续时间、家长对活动性鼻出血的治疗情况、病史、治疗及干预措施。记录鼻衄部位的位置、鼻黏膜类型、有无鼻前庭炎、鼻中隔偏曲的位置和类型、腺样体大小、下鼻甲肥大程度。结果:31例(62%)复发性鼻出血患者和14例(28%)无复发性鼻出血患者存在鼻出血偏离。鼻出血组的偏差明显高于对照组(p = 0.001)。复发性鼻出血组鼻黏膜类型为脆弱型37例(74%),血管化型11例(22%),脆弱-血管化型2例(4%)。鼻出血组鼻黏膜类型与鼻黏膜年龄、鼻黏膜是否存在偏曲、鼻黏膜偏曲位置、鼻黏膜类型有显著相关性(p = 0.005, p = 0.004, p = 0.008, p = 0.015)。结论:小儿鼻出血复发与鼻中隔偏曲、下鼻甲肥大、鼻黏膜类型有关。
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引用次数: 0
Evaluation Of Morbid Obese Patients İn Terms Of Sexual Dysfunctions: A Cross-Sectional Study 病态肥胖患者的评价İn性功能障碍方面:一项横断面研究
Pub Date : 2022-10-22 DOI: 10.30565/medalanya.1170379
B. Yaprak, L. Keskin, I. Sahin
Aim: Obesity is a risk factor for sexual dysfunction. The aim of this study is to investigate the frequency of sexual dysfunction in morbidly obese patients. Methods: The sample of the study consisted of 78 morbidly obese patients with BMI>40 kg/m2 and 68 individuals with normal weight. The data was obtained using the sociodemographic information form completed by the participants, Beck anxiety scale, Beck depression scale and Golombok Rust Inventory of Sexual Satisfaction. Results: The frequency of sexual dysfunction was found to be higher in obese women and men (p
目的:肥胖是性功能障碍的一个危险因素。本研究的目的是调查在病态肥胖患者性功能障碍的频率。方法:选取BMI>40 kg/m2的病态肥胖患者78例,体重正常者68例。数据采用被试填写的社会人口学信息表、Beck焦虑量表、Beck抑郁量表和Golombok Rust性满意度量表获得。结果:肥胖女性和肥胖男性出现性功能障碍的频率较高(p
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引用次数: 0
Assessment Of Femoral Notch Morphology In Male Patients With Anterior Cruciate Ligament Injury: An MRI Study 男性前交叉韧带损伤患者股骨切迹形态的评估:一项MRI研究
Pub Date : 2022-10-21 DOI: 10.30565/medalanya.1069144
A. Akgün, A. Tekcan
Aim: The objective of the present study was to evaluate the femoral notch type, notch width index (NWI), notch angle (NA) and α angle in patients with ACL injury and compare with nonathletic male population using magnetic resonance imaging (MRI). Methods: 79 patients with complete ACL tear and 80 patients as control group (aged 19-43 years) who had knee MRI were evaluated. NWI, NA measurements and notch shape were evaluated on axial fat-saturated proton-weighted sequences. Femoral notch shape was classified as A, U and W types. Results: A statistically significant association was found between notch type, NWI, NA and ACL injury (p
目的:应用磁共振成像技术(MRI)评价前交叉韧带损伤患者的股骨切迹类型、切迹宽度指数(NWI)、切迹角(NA)和α角,并与非运动男性进行比较。方法:对79例完全前交叉韧带撕裂患者和80例对照组(年龄19 ~ 43岁)行膝关节MRI检查。对轴向脂肪饱和质子加权序列进行NWI、NA测量和缺口形状评估。股骨切迹形状分为A型、U型和W型。结果:缺口类型、NWI、NA与ACL损伤有统计学意义(p
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引用次数: 0
Clinical Outcomes of Uniportal Versus Multiportal Endoscopic Thoracic Sympathectomy in Patients With Severe Palmar and Axillary Hyperhidrosis 单门静脉与多门静脉内窥镜胸椎交感神经切除术治疗重度掌腋多汗症的临床效果
Pub Date : 2022-08-20 DOI: 10.30565/medalanya.1106046
Oktay Aslaner
Objective: Palmar and axillary hyperhidrosis is caused by overstimulation of the sympathetic nervous system that control the sweat glands. This study compares the clinical consequences of uniportal and multiportal thoracic endoscopic thoracic sympathectomy (ETS), in cases of severe palmar and axillary hyperhidrosis. Methods: In this retrospective study, forty-one patients who were diagnosed as severe palmar and axillary primary hyperhidrosis were analyzed. These underwent multiportal ETS between 2015 and 2020 at our thoracic surgery clinic. They were divided into two groups, 24 as uniportal (58.5%) and 17 as multiportal (41.5%). They were compared in terms of the length of hospital stay, the initial complications and possible recurrences after three months. Descriptive statistics were used to evaluate stratified and continuous variables. Results: There was no significant difference in moderate pain between the two groups. There was a significant difference between the two groups in terms of 3 days or more hospitalization. There were no significant difference related to the rate of complications such as ptosis, Horner syndrome, increased duration of surgery and recurrence rate of hyperhidrosis 3 months after surgery. Some mild to moderate side effects disappeared spontaneously at 6-month follow-up.Conclusion: The results showed that uniportal and multiportal endoscopic thoracoscopic sympathectomy (EST) are very effective, safe and minimally invasive methods for the treatment of palmar and axillary hyperhidrosis. Compared to the multiportal approach, uniportal EST causes less postoperative pain and less surgical duration.
目的:掌腋多汗症是由控制汗腺的交感神经系统过度刺激引起的。本研究比较了单门静脉和多门静脉胸内窥镜胸交感神经切除术(ETS)治疗严重手掌和腋窝多汗症的临床效果。方法:回顾性分析41例确诊为重度掌腋原发性多汗症的患者。这些患者在2015年至2020年期间在我们的胸外科诊所接受了多门ETS。其中单门24例(58.5%),多门17例(41.5%)。比较两组患者住院时间、初始并发症及3个月后复发率。描述性统计用于评价分层和连续变量。结果:两组患者在中度疼痛方面无显著差异。两组住院3天及以上的差异有统计学意义。两组在上睑下垂、霍纳综合征、手术时间延长、术后3个月多汗症复发率等并发症发生率方面差异无统计学意义。一些轻中度的副作用在6个月的随访中自行消失。结论:单门及多门胸腔镜交感神经切除术是治疗掌腋多汗症有效、安全、微创的方法。与多门静脉入路相比,单门静脉EST术后疼痛少,手术时间短。
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引用次数: 0
yaşlılarda kalça kırığı; genel bir bakış
Pub Date : 2022-08-18 DOI: 10.30565/medalanya.1161785
Ahmet Aslan
hip fracture in elderly; an overwiev hip fracture in elderly; an overwiev hip fracture in elderly; an overwiev
老年髋部骨折;老年人完全性髋部骨折;老年人完全性髋部骨折;一个overwiev
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引用次数: 0
Sosyal ağ çeşitliliği ve sosyal desteğin sağlık çalışanlarının gelişimine etkisi
Pub Date : 2022-07-29 DOI: 10.30565/medalanya.1073643
Ozge Kilic, Merve YALÇINAY -İNAN, Esra Bilir, Ozge Pasi̇n, Kemal Kuşçu
Objectives: The well-being of healthcare workers is a critical indicator in the provision of high-quality care. Although researchers have stressed the importance of social interactions and social support, scarce data exist about their effects on healthcare workers’ well-being. In this study, we aim to advance the research on the relationships between social network diversity (SND), social support and thriving. Methods: In a cross-sectional design, an anonymous online link was shared among healthcare workers in a university hospital. The survey included questions on demographics, medical diseases, as well as items from the SND index, the multidimensional perceived social support scale, and the brief and comprehensive inventories of thriving scales. Results: A total of 103 individuals participated in the study (mean age ± standard deviation = 33±7.2; male/female = 33/70). Men and women did not differ in SND, perceived social support, or thriving scores. Healthcare workers older than 38 years exhibited higher scores in belonging (p=0.032), skills (p=0.006), self-worth (p=0.048), meaning and purpose (p
目标:保健工作者的福祉是提供高质量护理的关键指标。尽管研究人员强调了社会互动和社会支持的重要性,但关于它们对医护人员福祉的影响的数据很少。本研究旨在进一步探讨社会网络多样性、社会支持与成长之间的关系。方法:在横断面设计中,在大学医院的医护人员之间共享匿名在线链接。调查的问题包括人口统计、医疗疾病,以及SND指数、多维感知社会支持量表和繁荣量表的简短和全面清单中的项目。结果:共103人参与研究(平均年龄±标准差= 33±7.2;男性/女性= 33/70)。男性和女性在SND、感知到的社会支持或繁荣得分方面没有差异。年龄大于38岁的医护人员在归属感(p=0.032)、技能(p=0.006)、自我价值感(p=0.048)、意义和目的(p=0.048)方面得分较高
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引用次数: 0
期刊
Acta Medica Alanya
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