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Comparison of PET with PET/CT in detecting peritoneal carcinomatosis: a meta-analysis. PET与PET/CT检测腹膜癌的比较:一项荟萃分析。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0418-8
Jinkui Li, Ruifeng Yan, Junqiang Lei, Changqin Jiang

Purpose: The study aims to perform a meta-analysis to compare the diagnostic value of FDG PET with PET/CT in detecting peritoneal carcinomatosis (PC) to identify the potentially most useful diagnostic modality.

Methods: A computer-aided search was performed in the Cochrane Library, PubMed, EMBASE, Web of Science, the China Biological Medicine Database, VIP, China National Knowledge Infrastructure database, and Wanfang databases for articles concerning diagnosis of peritoneal metastases with PET or PET/CT. QUADAS was used to evaluate the included articles' quality.

Results: On a per-patient basis, the pooled sensitivity of PET/CT (84%) was significantly higher than that of PET (60%), and the pooled specificity of PET (98%) was markedly higher than that for PET/CT (94%). On a per-lesion basis, the pooled sensitivity and specificity of PET/CT were 87 and 95%, respectively. Only 1 PET study on a per-lesion basis, its sensitivity is 65.8 and specificity is 94.1%.

Conclusions: PET and PET/CT are powerful imaging techniques for detection and characterization of PC. PET/CT can be used as a screening tool and it may be acceptable to use PET as a diagnosis tool.

目的:本研究旨在进行荟萃分析,比较FDG PET与PET/CT在检测腹膜癌(PC)中的诊断价值,以确定潜在最有用的诊断方式。方法:计算机辅助检索Cochrane图书馆、PubMed、EMBASE、Web of Science、中国生物医学数据库、VIP、中国国家知识基础设施数据库和万方数据库中与PET或PET/CT诊断腹膜转移相关的文章。采用QUADAS评价纳入文献的质量。结果:在单个患者的基础上,PET/CT的合并敏感性(84%)显著高于PET (60%), PET的合并特异性(98%)显著高于PET/CT(94%)。在每个病灶的基础上,PET/CT的敏感性和特异性分别为87%和95%。仅对单个病灶进行1次PET检查,其敏感性为65.8,特异性为94.1%。结论:PET和PET/CT是检测和表征PC的有力成像技术。PET/CT可以作为筛查工具,也可以作为诊断工具。
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引用次数: 26
The initial experience of the upper abdominal CT angiography using low-concentration contrast medium on dual energy spectral CT. 双能谱CT低浓度造影剂对上腹部血管造影的初步体会。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0462-4
Lei Xin, Xiaotang Yang, Ning Huang, Xiaosong Du, Jianxin Zhang, Yanyan Wang, Lina Hou, Jinfang Gao

Objective: To investigate the feasibility of using Spectral CT imaging with low contrast medium in abdominal CT angiography (CTA).

Subjects and methods: 70 consecutive patients (40 men, 42.6 ± 20.4 years; 30 women, 46.7 ± 18.8 years) with suspected abdominal focal lesions were referred to CTA exam. They were randomly assigned into two groups. Group A: 35 patients underwent conventional CT scan of Tube voltage 120 kVp, automatic current modulation with a Noise Index of 12, ASIR 30%, and injected with Iohexol (350 mgI/ml). Group B: 35 patients underwent Spectral CT Imaging, with Tube current of 600 mA, injected with Iodixanol (270 mgI/ml). The optimal mono-energy keV was achieved using the optimal contrast noise ratio in abdominal aorta at the renal artery level relative to the erector spine muscle. Both groups were injected with an injection rate of 3.5 ml/s, and a contrast volume of 1.5 ml/kg body weight. The Hounsfield units (HU) and noise of the bilateral renal arteries and muscle of both groups, as well as the optimal monochromatic image set of Group B were measured. Two radiologists assessed all images with a 5-points scale. CTDIvol and DLP were recorded. Data were analyzed using student t test.

Results: The total iodine intake of Group B was 28% lower than that of Group A. The CNR of abdomen artery, celiac trunk, superior mesenteric artery, and renal artery in spectral group (at the best mono-energy of 53.0 keV) were higher than those in conventional CTA group (p < 0.001). The subjective image quality score of spectral CTA group was also rated higher than conventional CTA group (p < 0.001). CTDIvol, DLP, and effective dose of spectral group were all lower than conventional group, but there were no significant differences (p > 0.05).

Conclusion: With 28% contrast medium reduction and reduced radiation dose, CT angiography using spectral imaging and lower concentration contrast agent provided better image quality than conventional CTA.

目的:探讨低衬成像在腹部CT血管造影(CTA)中的可行性。对象与方法:连续70例患者(男性40例,42.6±20.4岁;30例(46.7±18.8岁)疑似腹部局灶性病变的妇女行CTA检查。他们被随机分为两组。A组:35例患者行常规CT扫描,管电压120 kVp,电流自动调制,噪声指数12,ASIR 30%,注射碘己醇(350 mgI/ml)。B组:35例患者行光谱CT成像,管电流600 mA,注射碘沙醇(270 mgI/ml)。利用腹主动脉肾动脉水平相对于竖脊肌的最佳对比噪声比获得最佳单能量keV。两组注射速度均为3.5 ml/s,造影剂体积为1.5 ml/kg体重。测量两组双侧肾动脉和肌肉的Hounsfield单位(HU)和噪声,以及B组最优单色图像集。两名放射科医生以5分制评估所有图像。记录CTDIvol和DLP。数据分析采用学生t检验。结果:B组总碘摄入量比a组低28%,光谱组腹动脉、腹腔干、肠系膜上动脉、肾动脉CNR(单能量最高为53.0 keV)高于常规CTA组(p < 0.05)。结论:在减少造影剂28%、降低辐射剂量的情况下,采用光谱成像和低浓度造影剂的CT血管造影比常规CTA成像质量更好。
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引用次数: 31
Suburothelial and extrinsic lesions of the urinary bladder: radiologic and pathologic features with emphasis on MR imaging. 膀胱上皮下病变和外源性病变:放射学和病理特征,重点是磁共振成像。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0467-z
Andrew D Chung, Nicola Schieda, Trevor A Flood, Ilias Cagiannos, Ania Z Kielar, Matthew D F McInnes, Evan S Siegelman

Objective: The purpose of this article is to present a contemporary review of the imaging appearance of diseases which affect the deeper layers of the urinary bladder, including both suburothelial and extrinsic pathologies, using radiologic-pathologic correlation.

Conclusion: Compared to the more common urothelial lesions, at cystoscopy, suburothelial and extrinsic diseases of the urinary bladder wall often have a non-specific appearance or may be occult. Cross-sectional imaging, in particular MRI, plays an integral role in diagnosis. Mesenchymal tumors have distinct imaging features on MRI. Leiomyomas are characteristically low signal intensity on T2-weighted (T2W) imaging and progressively enhance. Lipomas and lipomatous hypertrophy are diagnosed by the presence of macroscopic fat. Neurofibromas, hemangiomas, and paragangliomas are hyperintense on T2W sequences and hypervascular. Reactive lesions occur in the setting of chronic inflammation and include: nephrogenic adenoma, cystitis cystica, and cystitis glandularis. Imaging findings are commonly non-specific; however, a mass with internal cystic spaces in association with pelvic lipomatosis is suggestive of cystitis glandularis. Urachal anomalies may be complicated by infection or malignancy. Urachal mucinous adenocarcinoma has a poor prognosis and may present as a T2-hyperintense suburothelial/extrinsic mass centered in the bladder dome. Other diseases may extrinsically involve the urinary bladder by hematogenous and peritoneal spread, including infection, endometriosis, and malignancy. A familiarity with suburothelial and extrinsic pathologies of the urinary bladder is critical for the radiologist, who may be the first to suggest these diagnoses.

目的:本文的目的是介绍影响膀胱深层疾病的影像学表现,包括尿路上皮下和外在病理,利用影像学-病理相关性。结论:与更常见的尿路上皮病变相比,膀胱镜检查时,尿路上皮下病变和膀胱壁外源性病变往往具有非特异性或隐匿性。横断成像,特别是MRI,在诊断中起着不可或缺的作用。间充质瘤在MRI上具有明显的影像学特征。平滑肌瘤在t2加权(T2W)成像上表现为低信号强度,并逐渐增强。脂肪瘤和脂肪瘤性肥大是通过肉眼可见的脂肪来诊断的。神经纤维瘤、血管瘤和副神经节瘤在T2W序列上呈高信号和高血管。反应性病变发生在慢性炎症的背景下,包括:肾源性腺瘤、囊性膀胱炎和腺性膀胱炎。影像学表现通常是非特异性的;然而,与盆腔脂肪瘤病相关的内部囊性间隙肿块提示腺性膀胱炎。尿管异常可并发感染或恶性肿瘤。尿管粘液腺癌预后较差,可表现为以膀胱穹丘为中心的t2高水平上皮下/外源性肿块。其他疾病可通过血液和腹膜扩散外源性累及膀胱,包括感染、子宫内膜异位症和恶性肿瘤。熟悉膀胱上皮下和外在病理对放射科医生来说是至关重要的,他们可能是第一个提出这些诊断的人。
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引用次数: 18
MRI: first-line imaging modality for pregnant patients with suspected appendicitis. MRI:怀疑阑尾炎的孕妇的一线成像方式。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0540-7
Joseph Konrad, David Grand, Ana Lourenco

Purpose: The purpose of our study was to evaluate the sensitivity, specificity, and accuracy of ultrasound (US) as compared to magnetic resonance imaging (MRI) in pregnant patients with suspected appendicitis for visualization of the appendix, accuracy at diagnosing acute appendicitis, the ability of each modality to identify alternate diagnoses of pain and whether gestational age (GA) has an association with appendix identification rates.

Methods: We retrospectively reviewed the records of 140 pregnant patients with suspected appendicitis to determine the efficacy of US and MRI to identify the appendix, diagnose or exclude acute appendicitis, identify alternative etiologies for clinical presentation, and the affect of GA on identification of the appendix. Imaging results were correlated with surgical pathology in patients who underwent surgery. The electronic medical record was used to assess clinical outcomes in patients who did not undergo surgery.

Results: The appendix was visualized in 7% (8/117) of US exams and in 80% (91/114) of MRI exams. Alternate etiologies of pathology were determined in 3% (3/117) of US exams and 12% (14/114) of MRI exams. The sensitivity and specificity of MRI for acute appendicitis were both 100% and 98%, respectively, as compared to 18% and 99%, respectively, with US. GA did not affect MRI or ultrasound visualization rates of the appendix.

Conclusion: Given the low likelihood of visualization of the appendix at US, the excellent accuracy of MRI and the ability of MRI to identify alternate diagnoses, we suggest that at certain institutions MRI may be considered a first-line imaging modality for pregnant patients of any GA with suspected appendicitis.

目的:本研究的目的是评估超声(US)与磁共振成像(MRI)在疑似阑尾炎的妊娠患者阑尾显像的敏感性、特异性和准确性,诊断急性阑尾炎的准确性,每种方式识别替代疼痛诊断的能力,以及胎龄(GA)是否与阑尾识别率相关。方法:回顾性分析140例疑似阑尾炎的妊娠患者的临床资料,探讨超声和MRI对阑尾的鉴别、急性阑尾炎的诊断或排除、临床表现的替代病因以及超声对阑尾鉴别的影响。影像学结果与手术患者的手术病理相关。电子病历用于评估未接受手术的患者的临床结果。结果:阑尾显影率为7% (8/117),MRI显影率为80%(91/114)。在3%(3/117)的US检查和12%(14/114)的MRI检查中发现了不同的病理病因。MRI对急性阑尾炎的敏感性和特异性分别为100%和98%,而US的敏感性和特异性分别为18%和99%。GA不影响阑尾的MRI或超声显像率。结论:考虑到超声显示阑尾的可能性较低,MRI的准确性高,以及MRI识别替代诊断的能力,我们建议在某些机构,对于任何怀疑阑尾炎的妊娠GA患者,MRI可能被视为一线成像方式。
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引用次数: 51
Use of a web-based image reporting and tracking system for assessing abdominal imaging examination quality issues in a single practice. 使用基于网络的图像报告和跟踪系统评估腹部影像学检查质量问题。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0502-0
Andrew B Rosenkrantz, Evan Johnson, Joseph J Sanger

This article presents our local experience in the implementation of a real-time web-based system for reporting and tracking quality issues relating to abdominal imaging examinations. This system allows radiologists to electronically submit examination quality issues during clinical readouts. The submitted information is e-mailed to a designate for the given modality for further follow-up; the designate may subsequently enter text describing their response or action taken, which is e-mailed back to the radiologist. Review of 558 entries over a 6-year period demonstrated documentation of a broad range of examination quality issues, including specific issues relating to protocol deviation, post-processing errors, positioning errors, artifacts, and IT concerns. The most common issues varied among US, CT, MRI, radiography, and fluoroscopy. In addition, the most common issues resulting in a patient recall for repeat imaging (generally related to protocol deviation in MRI and US) were identified. In addition to submitting quality problems, radiologists also commonly used the tool to provide recognition of a well-performed examination. An electronic log of actions taken in response to radiologists' submissions indicated that both positive and negative feedback were commonly communicated to the performing technologist. Information generated using the tool can be used to guide subsequent quality improvement initiatives within a practice, including continued protocol standardization as well as education of technologists in the optimization of abdominal imaging examinations.

本文介绍了我们在实施实时基于网络的系统以报告和跟踪与腹部成像检查有关的质量问题方面的本地经验。该系统允许放射科医生在临床读数期间以电子方式提交检查质量问题。提交的信息通过电子邮件发送给给定方式的指定人员,以便进一步跟进;候选者随后可以输入描述他们的反应或采取的行动的文本,这些文本将通过电子邮件发送回放射科医生。在6年期间对558个条目的审查证明了广泛的审查质量问题的文档,包括与协议偏差、后处理错误、定位错误、工件和IT问题相关的特定问题。最常见的问题在美国,CT, MRI, x线摄影和透视中有所不同。此外,确定了导致患者回忆重复成像的最常见问题(通常与MRI和US的方案偏差有关)。除了提交质量问题外,放射科医生还通常使用该工具来提供对执行良好的检查的认可。对放射科医生提交的意见所采取的行动的电子日志表明,积极和消极的反馈通常都传达给了表演技师。使用该工具生成的信息可用于指导实践中后续的质量改进举措,包括持续的方案标准化以及腹部成像检查优化技术人员的教育。
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引用次数: 1
Variable color Doppler sonographic appearances of retained products of conception: radiologic-pathologic correlation. 妊娠保留产物的可变彩色多普勒超声表现:影像学-病理相关性。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0424-x
Aya Kamaya, Priya M Krishnarao, Ann K Folkins, R Brooke Jeffrey, Terry S Desser, Katherine E Maturen

Object of study: Retained products of conception (RPOC) displays variable vascularity, ranging from avascular to markedly vascular on color Doppler sonography. We hypothesize that variability in sonographic vascularity may be due to histopathologic variation in the placental tissue.

Materials, methods, and procedures: After institutional review board approval, sonographic images and pathologic specimens were retrospectively reviewed in 26 patients with pathologically proven RPOC. Ultrasound (US) images were scored 0-3 for the degree of vascularity by two radiologists blinded to the diagnosis. Corresponding pathologic specimens were evaluated for vascularization of chorionic villi, degree of inflammation, morphology of maternal arteries, chorionic villous preservation, and percentage of clot, membranes, chorionic villi, and decidua/myometrium. Statistical analysis, including multiple linear regression, was performed.

Results: RPOC with histologically avascular chorionic villi or those with markedly reduced vascularization had significantly lower US vascularity scores (p = 0.030) than those with chorionic villi showing normal or decreased vascularization. Sonographically avascular RPOC had a significantly lower percentage villi (p = 0.028) and higher percentage of decidua (p = 0.004) than specimens where US showed any Doppler vascularity. Histologic vascularity of villi (p = 0.049) and non-observation of maternal arteries (p = 0.001) were significant predictors of US vascularity scores in multivariate linear regression analysis, while inflammation of villi (p = 0.053) was a marginally significant predictor.

Significance of the conclusions: Histologic vascularity of villi appears to contribute to the observed variation in sonographic vascularity. This finding may underlie known differences in clinical outcomes between sonographic vascularity groups.

研究对象:彩色多普勒超声显示妊娠产物(RPOC)血管变化,从无血管到明显血管不等。我们假设超声血管的变异性可能是由于胎盘组织的组织病理学变异。材料、方法和程序:经机构审查委员会批准,回顾性分析26例经病理证实的RPOC患者的超声图像和病理标本。超声(US)图像评分0-3的程度的血管由两名放射科医生盲诊断。对相应的病理标本进行绒毛膜绒毛血管化、炎症程度、母体动脉形态、绒毛膜绒毛保存、血块、膜、绒毛膜绒毛和蜕膜/肌层百分比的评估。采用多元线性回归进行统计分析。结果:组织学上无血管性绒毛膜绒毛或血管化明显减少的RPOC的US血管化评分明显低于血管化正常或减少的绒毛膜绒毛患者(p = 0.030)。超声无血管RPOC的绒毛百分比明显低于超声多普勒血管显示的标本(p = 0.028),蜕膜百分比明显高于超声多普勒血管显示的标本(p = 0.004)。在多元线性回归分析中,绒毛组织学血管通畅(p = 0.049)和未观察到母体动脉(p = 0.001)是US血管通畅评分的显著预测因子,而绒毛炎症(p = 0.053)是一个边际显著的预测因子。结论的意义:绒毛的组织学血管性似乎有助于超声检查血管性的变化。这一发现可能是超声血管组之间临床结果已知差异的基础。
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引用次数: 5
The "pear-shaped" bladder. “梨形”膀胱。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0470-4
William Jeffrey Triffo, Raymond B Dyer
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引用次数: 0
Case report: MR imaging features of disseminated uterine leiomyosarcoma presenting after hysterectomy with morcellation. 病例报告:子宫切除术后播散性子宫平滑肌肉瘤的MR影像特征。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0486-9
Tadi Ciszak, Pardeep K Mittal, Patrick Sullivan, Kenneth Cardona, Krisztina Z Hanley, Namita Khanna, Courtney Coursey Moreno

A 53-year-old woman underwent elective hysterectomy for symptomatic anemia secondary to abnormal uterine bleeding. She presented 15 months later with complaints of abdominal fullness. Abdominopelvic magnetic resonance imaging demonstrated multiple confluent enhancing solid masses centered in the pelvis and extending cranially to the level of the umbilicus. Additional separate nodules also were visible along the peritoneum. Biopsy demonstrated leiomyosarcoma. Additional clinical information was obtained, which revealed that the patient's prior hysterectomy was performed with morcellation. In November 2014, the United States Food and Drug Administration issued a warning discouraging the use of morcellation during hysterectomy and myomectomy because of the risk of seeding unsuspected malignancy. Radiologists should be aware of this potential complication of morcellation and its imaging appearance so that the correct diagnosis can be suggested in the imaging report.

一名53岁妇女,因子宫异常出血继发的症状性贫血而行选择性子宫切除术。15个月后,她主诉腹部充盈。腹部骨盆磁共振成像显示以骨盆为中心的多个融合增强实性肿块,并向颅骨延伸至脐水平。沿腹膜也可见其他单独的结节。活检显示为平滑肌肉瘤。获得了额外的临床信息,显示患者先前的子宫切除术是分块术。2014年11月,美国食品和药物管理局(fda)发布了一项警告,不鼓励在子宫切除术和子宫肌瘤切除术中使用分块术,因为有可能产生未经怀疑的恶性肿瘤。放射科医生应该意识到这种潜在的并发症及其影像学表现,以便在影像学报告中提出正确的诊断建议。
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引用次数: 5
Spectrum of abdominal imaging findings in histiocytic disorders. 组织细胞疾病的腹部影像学表现谱。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0449-1
Natally de Souza Maciel Rocha Horvat, Clovis Rego Coelho, Larissa Cardoso Roza, Rodrigo Canellas de Souza, Yves Bohrer Costa, Ebe Christie de Oliveira, Manoel de Souza Rocha, Ronaldo Hueb Baroni

Objectives: The present article provides an overview of the spectrum of abdominal findings of histiocytic disorders that may be observed in multimodality imaging illustrated by clinical cases from our Imaging Center.

Methods: We will review abdominal findings of Langerhans cell histiocytosis, Rosai-Dorfman disease, Erdheim-Chester disease, and hemophagocytic syndrome illustrated by clinical cases from our imaging department with histologic correlation.

Results: Abdominal involvement of histiocytic disorders is rare and may occur in the liver, biliary tract, kidney, retroperitoneum, kidney, gastrointestinal tract, and lymph nodes.

Conclusion: Histiocytic disorders encompass a group of rare diseases with a wide range of manifestations in which the abdominal involvement is quite infrequent. The role of the radiologist is to report the major imaging findings and the differential diagnosis; however, the imaging features are unspecific and biopsy usually is necessary to establish the definitive diagnosis.

目的:本文概述了我们影像中心的临床病例在多模态成像中可能观察到的组织细胞疾病的腹部表现。方法:我们将回顾Langerhans细胞组织细胞增多症、roshai - dorfman病、Erdheim-Chester病和噬血细胞综合征的腹部表现,并结合影像科的临床病例进行组织学分析。结果:组织细胞疾病的腹部累及是罕见的,可能发生在肝脏、胆道、肾脏、腹膜后、肾脏、胃肠道和淋巴结。结论:组织细胞疾病是一组罕见的疾病,表现广泛,累及腹部是相当罕见的。放射科医生的作用是报告主要影像学表现和鉴别诊断;然而,影像学特征不明确,活检通常是建立明确诊断所必需的。
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引用次数: 8
The horseshoe kidney. 马蹄肾。
Pub Date : 2015-10-01 DOI: 10.1007/s00261-015-0454-4
Michelle D Sakala, Raymond B Dyer
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引用次数: 3
期刊
Abdominal Imaging
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