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[Anterior sternoclavicular dislocation, description of surgical technique]. [胸锁关节前脱位,手术技巧描述]。
Pub Date : 2022-01-01
G Fraind-Maya, G A Pons-Carrera

Sternoclavicular joint dislocation is an uncommon injury and is usually consequential to high-energy trauma. These can be classified as anterior or retro-sternal (posterior) dislocation. Sometimes they can be accompanied by injury to large vessels due to their anatomical proximity mainly retrosternal. Conceptually closed reduction is indicated as the first line of treatment in acute injuries and open reduction tends to be for failing the previous one. We present a case of anterior clavicular sternal dislocation, with recurrence after closed reduction under anesthesia and surgically operated with reconstruction and allograft use with favorable evolution six years after its surgical procedure.

胸锁关节脱位是一种不常见的损伤,通常由高能量创伤引起。可分为前脱位和胸骨后(后)脱位。由于胸骨后脱位在解剖学上主要靠近大血管,因此有时可能伴有大血管损伤。从概念上讲,闭合复位术是急性损伤的第一线治疗方法,而开放复位术往往用于前者失败的情况。我们介绍了一例锁骨胸骨前脱位病例,该病例在麻醉下闭合复位后复发,经手术重建并使用同种异体材料,手术后六年病情发展良好。
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引用次数: 0
[Treatment of severe spinal deformity with 3D printing models]. 【用3D打印模型治疗严重脊柱畸形】。
Pub Date : 2022-01-01
R G Evia-Cabral, E H Hermida-Ochoa, D Benavides-Rodríguez, J L Cuevas-Andrade, T B Uribe-Cortés, J C Hermida-Ochoa

Introduction: Scoliosis is a complex deformity that affects all three planes of the axis of the spine. The association between neuromuscular pathology and vertebral alignment was initially described in 1960. Neuromuscular pathology is progressive and results in postural abnormalities. Surgical goals in patients with neuromuscular deformity include anatomical correction for sedation and ambulation, as well as functional improvement. The gold standard of treatment is by posterior approach with transpedicular screws. The "hands-free" technique saves surgical time, decreases radiation by reducing the use of fluoroscopy. The advent of 3D printing technology allows precise study of the anatomical area and detail of the deformity in its three planes. This model can be sterilized for transoperative guidance. A 13-year-old female patient who develops thoracolumbar neuromuscular scoliosis secondary to spastic cerebral palsy (CP), with previous instrumentation T11-L3 of which he develops severe proximal curve. After the segmentation of the three-dimensional model, pedicle violation greater than 2 mm towards bilateral medullary canal was detected in the pedicles of L1 and L2 of previous instrumentation, pedicle dysplasia and the morphological characteristics of the pedicles were observed. Three-dimensional planning and the use of surgical guides represent a tool for surgical planning, especially in severe cases and with pedicle dysplasia. It helps as a surgical guide for the placement of hands-free transpedicular screws with possible reduction of radiation and anesthetic time.

简介:脊柱侧凸是一种复杂的畸形,影响脊柱轴的所有三个平面。神经肌肉病理和椎体排列之间的联系最初是在1960年描述的。神经肌肉病理是进行性的,并导致姿势异常。神经肌肉畸形患者的手术目标包括解剖矫正镇静和活动,以及功能改善。治疗的金标准是经椎弓根螺钉后路入路。这种“免提”技术节省了手术时间,通过减少透视检查的使用减少了辐射。3D打印技术的出现允许在其三个平面上精确研究畸形的解剖区域和细节。该模型可以消毒,以指导手术。一名13岁女性患者,继发于痉挛性脑瘫(CP)的胸腰椎神经肌肉侧凸,既往有T11-L3内固定,并出现严重的近端弯曲。三维模型分割后,既往内固定L1、L2椎弓根向双侧髓管方向侵犯大于2mm,观察椎弓根发育不良及形态学特征。三维规划和手术指南的使用是手术规划的一种工具,特别是在严重病例和椎弓根发育不良的情况下。它有助于作为手术指导放置免手椎弓根螺钉,可能减少辐射和麻醉时间。
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引用次数: 0
[3D Printing and Orthopedics of Mexico]. [墨西哥的 3D 打印和矫形学]。
Pub Date : 2022-01-01
M I Encalada-Díaz

No Abstract available.

无摘要。
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引用次数: 0
[Lateral osteotomy of the calcaneus in the treatment of Müller-Weiss disease]. 【跟骨外侧截骨术治疗<s:1> ller- weiss病】。
Pub Date : 2022-01-01
V Ponz-Lueza, J E Galeote-Rodríguez, J P García-Paños, F J Carrillo-Piñero, J García-García, F Marco-Martínez

Introduction: The deforming condition of the navicular bone known as Müller-Weiss disease (MWD) is a rare disease. Patients present with chronic pain in the talonavicular joint and a paradoxical flat foot with a varo hindfoot.

Objective: To analyze the clinical results of a lateral osteotomy of calcaneus applied to patients with MWD.

Material and methods: Retrospective observational study carried out in two hospitals. The series consists of nine cases in eight patients, all of them with symptomatic Müller-Weiss disease, treated by lateral osteotomy of the calcaneus between 2012 and 2017, obtaining an average follow-up of 4 years (2-6). The mean age was 62 years (50-75). In all patients, Costa-Bartani angles (CB), Kite angle and Calcaneal Inclination (CI) were measured. In addition, the Manchester Oxford Scale (MO) to measure the post-surgical satisfaction of patients.

Results: All patients report having improved their pain by obtaining a postoperative score on the mean Manchester Oxford scale of 32.54 points (15.62-53.75). In 66% of patients the CB angle improves, the Kite angle in 89% and the CI in 33%.

Conclusion: The improvement in the pain of the patients in our series is not accompanied by radiological changes in the same proportion, it is a simple and uncomplicated technique in our follow-up.

简介:舟骨的变形状况被称为勒-韦斯病(MWD)是一种罕见的疾病。患者表现为距舟关节慢性疼痛和后足内翻的矛盾性平足。目的:分析跟骨外侧截骨术治疗MWD的临床效果。材料与方法:在两家医院进行回顾性观察研究。该系列包括8例9例患者,均有症状性 ller- weiss病,于2012 - 2017年间行跟骨外侧截骨术治疗,平均随访4年(2-6)。平均年龄62岁(50-75岁)。所有患者均测量Costa-Bartani角(CB)、Kite角和跟骨倾斜度(CI)。此外,采用曼彻斯特牛津量表(MO)来衡量患者的术后满意度。结果:所有患者术后的平均曼彻斯特牛津评分为32.54分(15.62-53.75),疼痛得到改善。66%的患者CB角改善,89%的患者Kite角改善,33%的患者CI改善。结论:本系列患者疼痛的改善并没有同等比例的影像学改变,在我们的随访中是一种简单易行的技术。
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引用次数: 0
[Direct medical cost of late rehabilitation in workers with conservatively managed proximal humerus fracture]. 保守治疗肱骨近端骨折工人后期康复的直接医疗费用
Pub Date : 2022-01-01
B I Navarrete-Peñaloza, H Hernández-Amaro

Introduction: Eighty percent of the Proximal humerus fractures are not displaced or minimally displaced and stable. The international treatment recommendation is conservative. Immobilization of the limb carries risk of stiffness, pain and decreased function. Currently being used rehabilitation programs with early mobilization of the injured shoulder within the first week post-fracture, with evidence of early functional and labor recovery and with no risk for displacement of fragments. However, in our country, these patients start rehabilitation late, which leads to a delay in the recovery of functionality and delay in returning to work, translating into increased costs. At the moment there is no national benchmark for the cost of this late-onset rehabilitation.

Material and methods: From a non-probabilistic sample for convenience, were analyzed records of 52 patients, treated in the period from January to December 2019. Inclusion criteria were workers diagnosed with a proximal humeral fracture, conservative management; exclusion criteria were peripheral nerve injury, aggregate fracture or surgically treated.

Results: The mean direct medical cost was $19,090.69 Mexican pesos, directly proportional to the days of stay in the unit and disability.

Conclusion: Late rehabilitation leads to more days of disability than recommended by the based guidelinesin the workload, therefore, higher cost.

80%的肱骨近端骨折不移位或轻度移位且稳定。国际上的治疗建议是保守的。固定肢体有僵硬、疼痛和功能下降的风险。目前使用的康复方案是在骨折后的第一周内早期活动受伤的肩膀,有证据表明早期功能和劳动恢复,没有碎片移位的风险。然而,在我国,这些患者开始康复较晚,导致功能恢复和重返工作岗位的延迟,转化为成本增加。目前,对于这种迟发性康复的费用,还没有全国性的基准。材料和方法:为方便起见,从非概率样本中分析2019年1月至12月期间治疗的52例患者的记录。入选标准为确诊肱骨近端骨折的工人,保守治疗;排除标准为周围神经损伤、骨性骨折或手术治疗。结果:平均直接医疗费用为19,090.69墨西哥比索,与住院天数和残疾成正比。结论:在工作量上,延迟康复导致的残疾天数比基础指南推荐的要多,因此成本更高。
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引用次数: 0
[Validation of the modified IMPROVE scale in patients undergoing primary total hip arthroplasty]. [改良改良改良量表在初次全髋关节置换术患者中的验证]。
Pub Date : 2022-01-01
E A Ríos-Zavala, B Araiza-Nava, A M Morales-López, J M Jiménez-Capetillo, R Esquivel-Gómez, G E Reyes-Meza

Introduction: Major orthopedic surgery such as total hip arthroplasty (THA) is associated with an increased risk of postoperative complications. Candidates for THA are often older adults, with comorbidities that increase the risk of major bleeding, the IMPROVE scale has independent actors on the risk of bleeding according to the characteristics of the patients at hospital admission. It foresees the possibility of hemorrhage and the need for blood transfusion, being support in decision-making in the planning of a safe THA with the provision of the necessary resources.

Objective: To evaluate the sensitivity, validity and reliability of the modified IMPROVE scale in patients undergoing primary total hip arthroplasty.

Material and methods: Study of processes with a sample of 131 patients undergoing primary THA, in the period from January 01, 2018 to July 01, 2018.

Results: The scale presents good reliability, as for the performance of the scale, a good sensitivity was obtained, classifying 96.9% of the patients correctly; which is suitable for the type of scale.

Conclusions: The modified IMPROVE scale is a discretely adequate and useful tool for the prognosis of bleeding risk in patients who undergo THA, compared with other assessment scales developed in other geographical areas. It is recommended to continue with the study of risk factors for major bleeding in this specific population.

主要的骨科手术,如全髋关节置换术(THA)与术后并发症的风险增加有关。THA的候选者通常是老年人,有增加大出血风险的合并症,根据住院患者的特点,改进量表对出血风险有独立的影响因素。它预见出血的可能性和输血的需要,在提供必要资源的情况下,为规划安全的人工流产手术的决策提供支持。目的:评价改良改良改良量表在初次全髋关节置换术中的敏感性、效度和信度。材料与方法:对2018年1月1日至2018年7月1日131例原发性THA患者的过程进行研究。结果:量表具有较好的信度,量表的灵敏度较高,对患者的正确率为96.9%;这是适合的规模类型。结论:与其他地区开发的其他评估量表相比,改进的改进量表是评估THA患者出血风险预后的适当和有用的工具。建议继续研究这一特定人群大出血的危险因素。
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引用次数: 0
[Applications of tranexamic acid in Orthopaedics and Traumatology]. [氨甲环酸在骨科和创伤学中的应用]
Pub Date : 2021-11-01
R Berebichez-Fridman, F G Castillo-Vázquez, E Berebichez-Fastlicht

Introduction: Tranexamic acid is an antifibrinolytic drug which has been used in many disciplines of Medicine, as well as in Orthopaedics and Traumatology, with the objective of diminishing and preventing blood loss and the necessity of allogenic blood transfusion. This study has the objective to demonstrate the uses, indications and contraindications of tranexamic acid in the different subspecialties of Orthopaedics and Traumatology.

Material and methods: A through search was performed looking at the most recent evidence regarding the use of tranexamic acid in the different subspecialties of Orthopaedics and Traumatology, as well as its indications, contraindications and adverse effects.

Results: Tranexamic acid has a great amount of applications in Orthopaedics and Traumatology, especially in primary and revision knee and hip arthroplasties, spine surgery and trauma. It has been observed that tranexamic acid is effective in diminishing perioperative bleeding, less necessity of blood transfusion, among other benefits. Tranexamic acid is a safe drug, which does not increase the risk of developing thrombotic events in healthy patients. There are a number of administration routes of tranexamic acid as well as many dosage regimens, all being efficient. Therefore, no standardization regarding the best administration route and most effective dose has been established.

Conclusions: Tranexamic acid is a safe and effective drug for diminishing perioperative bleeding and to avoid the necessity of blood transfusion, with many applications in Orthopaedics and Traumatology.

简介:氨甲环酸是一种抗纤溶药物,已被用于许多医学学科,以及骨科和创伤学,目的是减少和预防失血和输血的必要性。本研究的目的是展示氨甲环酸在骨科和创伤学不同亚专科的使用、适应症和禁忌症。材料和方法:通过搜索,查看有关氨甲环酸在骨科和创伤学不同亚专科使用的最新证据,以及其适应症、禁忌症和不良反应。结果:氨甲环酸在骨科和创伤学中有广泛的应用,尤其是在膝关节置换术、脊柱外科和创伤手术中。据观察,氨甲环酸在减少围手术期出血、减少输血必要性等方面是有效的。氨甲环酸是一种安全的药物,不会增加健康患者发生血栓事件的风险。氨甲环酸有多种给药途径和多种给药方案,都是有效的。因此,最佳给药途径和最有效剂量尚未建立标准化。结论:氨甲环酸是一种安全有效的减少围手术期出血和避免输血的药物,在骨科和创伤学中有广泛的应用。
{"title":"[Applications of tranexamic acid in Orthopaedics and Traumatology].","authors":"R Berebichez-Fridman,&nbsp;F G Castillo-Vázquez,&nbsp;E Berebichez-Fastlicht","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Tranexamic acid is an antifibrinolytic drug which has been used in many disciplines of Medicine, as well as in Orthopaedics and Traumatology, with the objective of diminishing and preventing blood loss and the necessity of allogenic blood transfusion. This study has the objective to demonstrate the uses, indications and contraindications of tranexamic acid in the different subspecialties of Orthopaedics and Traumatology.</p><p><strong>Material and methods: </strong>A through search was performed looking at the most recent evidence regarding the use of tranexamic acid in the different subspecialties of Orthopaedics and Traumatology, as well as its indications, contraindications and adverse effects.</p><p><strong>Results: </strong>Tranexamic acid has a great amount of applications in Orthopaedics and Traumatology, especially in primary and revision knee and hip arthroplasties, spine surgery and trauma. It has been observed that tranexamic acid is effective in diminishing perioperative bleeding, less necessity of blood transfusion, among other benefits. Tranexamic acid is a safe drug, which does not increase the risk of developing thrombotic events in healthy patients. There are a number of administration routes of tranexamic acid as well as many dosage regimens, all being efficient. Therefore, no standardization regarding the best administration route and most effective dose has been established.</p><p><strong>Conclusions: </strong>Tranexamic acid is a safe and effective drug for diminishing perioperative bleeding and to avoid the necessity of blood transfusion, with many applications in Orthopaedics and Traumatology.</p>","PeriodicalId":7081,"journal":{"name":"Acta ortopedica mexicana","volume":"35 6","pages":"539-546"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40564566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diagnosis of SCIWORA associated with Brown Séquard syndrome in an adolescent]. [青少年与布朗ssamquard综合征相关的SCIWORA的诊断]。
Pub Date : 2021-11-01
D A García-Cabra, D Jerez-Fidencio

SCIWORA (Spinal Cord Injury without Radiologic Abnormality) is a rare condition that mainly affects pediatric patients; We present the case of a teenage male patient diagnosed with SCIWORA/Brown Séquard Syndrome. In admission, he has multiple bruises on his neck and right hemibody and immediately he refers paraesthesia in all four limbs and spastic hemiparesis with right predominance, as well as inability to stand up and urinary continence. Treatment based on NASCIS III study is initiated and after the imaging tests, a diagnosis has already been made. We present the most current definitions of SCIWORA and the recommendations to make its diagnosis, as well as its relationship and coexistence with spinal syndromes.

无放射学异常脊髓损伤(SCIWORA)是一种罕见的疾病,主要影响儿科患者;我们报告一例青少年男性患者被诊断为SCIWORA/Brown ssamquard综合征。入院时,患者颈部和右半身有多处瘀伤,立即表示四肢感觉异常,右侧占优势的痉挛性偏瘫,以及无法站立和尿失禁。根据NASCIS III研究开始治疗,在影像学检查后,已经做出诊断。我们提出SCIWORA的最新定义和诊断建议,以及它与脊柱综合征的关系和共存。
{"title":"[Diagnosis of SCIWORA associated with Brown Séquard syndrome in an adolescent].","authors":"D A García-Cabra,&nbsp;D Jerez-Fidencio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>SCIWORA (Spinal Cord Injury without Radiologic Abnormality) is a rare condition that mainly affects pediatric patients; We present the case of a teenage male patient diagnosed with SCIWORA/Brown Séquard Syndrome. In admission, he has multiple bruises on his neck and right hemibody and immediately he refers paraesthesia in all four limbs and spastic hemiparesis with right predominance, as well as inability to stand up and urinary continence. Treatment based on NASCIS III study is initiated and after the imaging tests, a diagnosis has already been made. We present the most current definitions of SCIWORA and the recommendations to make its diagnosis, as well as its relationship and coexistence with spinal syndromes.</p>","PeriodicalId":7081,"journal":{"name":"Acta ortopedica mexicana","volume":"35 6","pages":"557-559"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40566523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment results of a modified Eden-Hybinette technique for anterior shoulder instability. 改良的Eden-Hybinette技术治疗前肩不稳的结果。
Pub Date : 2021-11-01
A A Cortes-De la Fuente, G Valencia-Martínez, O Martínez-Montiel

Introduction: Glenohumeral instability occurs in active-age patients with high recurrence rates in previously described treatments. The objective of the study was to analyze the functional and radiographic results of the patients that underwent a modified Eden-Hybinette technique.

Material and methods: From January 2017 to December 2019, 14 patients with post-traumatic anterior glenohumeral instability with glenoid bone loss higher or equal to 15% with or without Hill-Sachs lesion were included, qe used the modified Eden-Hybinette technique and outcomes were evaluated with WOSI and ROWE scales pre and post-procedure at 6, 12, and 24 months follow-up, a CT scan was performed at 6 weeks to evaluate the integration of the graft.

Results: Five women (35%) and nine men (65%) with a mean age of 39.1 (± 14) years were included. Ten involved the right shoulder (71.4%) and four the left one (28.5%). The results of WOSI and ROWE scales were statistically significant (p 0.05) in postsurgical evaluations as in all periods analyzed in contrast to a pre-surgical standing point; components of the WOSI test were also viewed separately (Sports, Lifestyle, Emotion, and Physical Symptoms) to assess if any of those separately could've altered or significantly influenced the total score obtained, but we found statistical significance (p 0.05) in all parameters. There was no recurrence or complications until the last follow-up.

Conclusions: The modified Eden-Hybinette technique offers good short-term functional results. It is a safe technique. Further studies are necessary to determine the effectiveness and possible long-term results and complications.

肱骨关节不稳定发生在活动年龄患者中,在先前描述的治疗中具有高复发率。本研究的目的是分析接受改良的Eden-Hybinette技术的患者的功能和影像学结果。材料和方法:2017年1月至2019年12月,纳入14例外伤性肱骨前不稳伴或不伴Hill-Sachs病变的肩关节骨丢失≥15%的患者,采用改良的Eden-Hybinette技术,并在随访6、12和24个月时采用WOSI和ROWE量表评估术前和术后结果,6周时进行CT扫描以评估移植物的整合。结果:女性5例(35%),男性9例(65%),平均年龄39.1(±14)岁。右肩10例(71.4%),左肩4例(28.5%)。与术前站立点相比,WOSI和ROWE量表在术后评估中的结果具有统计学意义(p 0.05);我们还分别考察了WOSI测试的组成部分(运动、生活方式、情绪和身体症状),以评估这些组成部分是否会改变或显著影响获得的总分,但我们发现所有参数都具有统计学意义(p 0.05)。最后一次随访前均无复发及并发症。结论:改良的Eden-Hybinette技术具有良好的短期功能效果。这是一种安全的技术。进一步的研究是必要的,以确定有效性和可能的长期结果和并发症。
{"title":"Treatment results of a modified Eden-Hybinette technique for anterior shoulder instability.","authors":"A A Cortes-De la Fuente,&nbsp;G Valencia-Martínez,&nbsp;O Martínez-Montiel","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Glenohumeral instability occurs in active-age patients with high recurrence rates in previously described treatments. The objective of the study was to analyze the functional and radiographic results of the patients that underwent a modified Eden-Hybinette technique.</p><p><strong>Material and methods: </strong>From January 2017 to December 2019, 14 patients with post-traumatic anterior glenohumeral instability with glenoid bone loss higher or equal to 15% with or without Hill-Sachs lesion were included, qe used the modified Eden-Hybinette technique and outcomes were evaluated with WOSI and ROWE scales pre and post-procedure at 6, 12, and 24 months follow-up, a CT scan was performed at 6 weeks to evaluate the integration of the graft.</p><p><strong>Results: </strong>Five women (35%) and nine men (65%) with a mean age of 39.1 (± 14) years were included. Ten involved the right shoulder (71.4%) and four the left one (28.5%). The results of WOSI and ROWE scales were statistically significant (p 0.05) in postsurgical evaluations as in all periods analyzed in contrast to a pre-surgical standing point; components of the WOSI test were also viewed separately (Sports, Lifestyle, Emotion, and Physical Symptoms) to assess if any of those separately could've altered or significantly influenced the total score obtained, but we found statistical significance (p 0.05) in all parameters. There was no recurrence or complications until the last follow-up.</p><p><strong>Conclusions: </strong>The modified Eden-Hybinette technique offers good short-term functional results. It is a safe technique. Further studies are necessary to determine the effectiveness and possible long-term results and complications.</p>","PeriodicalId":7081,"journal":{"name":"Acta ortopedica mexicana","volume":"35 6","pages":"534-538"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40564565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of combined administration of erythropoietin and iron in comparison to iron therapy alone in orthopaedic surgery: systematic review and metanalysis. 在骨科手术中,与单用铁治疗相比,促红细胞生成素和铁联合给药的疗效和安全性:系统评价和荟萃分析。
Pub Date : 2021-11-01
M Kaur, K Khatri, A Kankaria, T Dhir, H Arora

Introduction: Iron deficiency anaemia in orthopaedic surgery is common and there is increased risk of blood transfusion and associated adverse reactions. The management involves administration of iron (oral or intravenous) and erythropoietin stimulating agents.

Material and methods: We searched for PubMed, Embase, Google Scholar and Cochrane database to identify the studies from inception to April 2021. Randomized controlled trials with adult patients undergoing orthopedic surgery were included. The metanalysis compared patients who were administered combination of erythropoietin stimulating agents and iron in one group and iron alone. The primary outcome was the rate of blood transfusion and the secondary outcome studied were postoperative hemoglobin concentration, after treatment hemoglobin levels, and complications like mortality, stroke, myocardial infarction, deep vein thrombosis, pulmonary embolism and renal dysfunction.

Results: Eleven studies were included. The combination of ESA and iron decreased number of patients who required blood transfusion in comparison to patients treated with iron therapy alone (RR, 0.73; 95% CI, 0.59 to 0.91, I.

Conclusion: 2 = 65%; p = 0.005). In subgroup analysis with oral and intravenous iron, the difference was not statistically significant (p = 0.24). Administration of erythropoietin either in high ( 80,000 IU) or low dose ( 80,000 IU) resulted in lower blood transfusion rates (p = 0.0007) with no significant difference between groups. The risk of mortality, myocardial infarction, stroke, deep vein thrombosis or pulmonary embolism did not significantly increase. Combined administration of ESA and iron versus iron only reduces the number of red blood cell transfusions in the postoperative period in orthopedic procedures with minimal risk of complications.

缺铁性贫血在骨科手术中很常见,输血和相关不良反应的风险增加。治疗包括口服或静脉注射铁和促红细胞生成素。材料和方法:我们检索了PubMed、Embase、Google Scholar和Cochrane数据库,以确定从开始到2021年4月的研究。纳入了接受骨科手术的成年患者的随机对照试验。荟萃分析比较了一组联合使用促红细胞生成素和铁的患者和单独使用铁的患者。主要转归为输血率,次要转归为术后血红蛋白浓度、治疗后血红蛋白水平、死亡率、卒中、心肌梗死、深静脉血栓形成、肺栓塞、肾功能不全等并发症。结果:纳入11项研究。与单独接受铁治疗的患者相比,ESA和铁联合治疗减少了需要输血的患者人数(RR, 0.73;95% CI, 0.59 ~ 0.91, 1 .结论:2 = 65%;P = 0.005)。在口服和静脉注射铁的亚组分析中,差异无统计学意义(p = 0.24)。高剂量(80000 IU)或低剂量(80000 IU)促红细胞生成素组输血率较低(p = 0.0007),组间差异无统计学意义。死亡、心肌梗死、中风、深静脉血栓形成或肺栓塞的风险没有明显增加。ESA和铁与铁的联合使用只减少骨科手术术后红细胞输注的数量,并发症的风险最小。
{"title":"Efficacy and safety of combined administration of erythropoietin and iron in comparison to iron therapy alone in orthopaedic surgery: systematic review and metanalysis.","authors":"M Kaur,&nbsp;K Khatri,&nbsp;A Kankaria,&nbsp;T Dhir,&nbsp;H Arora","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Iron deficiency anaemia in orthopaedic surgery is common and there is increased risk of blood transfusion and associated adverse reactions. The management involves administration of iron (oral or intravenous) and erythropoietin stimulating agents.</p><p><strong>Material and methods: </strong>We searched for PubMed, Embase, Google Scholar and Cochrane database to identify the studies from inception to April 2021. Randomized controlled trials with adult patients undergoing orthopedic surgery were included. The metanalysis compared patients who were administered combination of erythropoietin stimulating agents and iron in one group and iron alone. The primary outcome was the rate of blood transfusion and the secondary outcome studied were postoperative hemoglobin concentration, after treatment hemoglobin levels, and complications like mortality, stroke, myocardial infarction, deep vein thrombosis, pulmonary embolism and renal dysfunction.</p><p><strong>Results: </strong>Eleven studies were included. The combination of ESA and iron decreased number of patients who required blood transfusion in comparison to patients treated with iron therapy alone (RR, 0.73; 95% CI, 0.59 to 0.91, I.</p><p><strong>Conclusion: </strong><ref id=\"2\">2</ref> = 65%; p = 0.005). In subgroup analysis with oral and intravenous iron, the difference was not statistically significant (p = 0.24). Administration of erythropoietin either in high ( 80,000 IU) or low dose ( 80,000 IU) resulted in lower blood transfusion rates (p = 0.0007) with no significant difference between groups. The risk of mortality, myocardial infarction, stroke, deep vein thrombosis or pulmonary embolism did not significantly increase. Combined administration of ESA and iron versus iron only reduces the number of red blood cell transfusions in the postoperative period in orthopedic procedures with minimal risk of complications.</p>","PeriodicalId":7081,"journal":{"name":"Acta ortopedica mexicana","volume":"35 6","pages":"547-556"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40564568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Acta ortopedica mexicana
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