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Characteristics of fingertip injuries and proposal of a treatment algorithm from a hand surgery referral center in Mexico City. 墨西哥城某手外科转诊中心指尖损伤特征及治疗算法的提出。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021113
E Telich-Tarriba, I Santos-Gallegos, A Cardenas-Mejia, C Arroyo-Berezowsky

Background: Fingertips are the most commonly injured anatomical structures in the upper extremity. The aim of this work is to present our experience in the management of fingertip injuries.

Methods: All patients with fingertip injuries managed by Plastic and Reconstructive Surgery Division of Hospital General “Dr Manuel Gea Gonzalez” in Mexico from July 2010 to June 2015 were included; their demographic characteristics were described, as well as patterns of injury and management.

Results: A total of 1,265 patients were included in the study, 75% were males. The mean age of presentation was 20.5 ± 16.46 years; the age group most commonly affected was younger than 15 years (46.7%). Right and left-sided injuries were almost equally prevalent (51 vs. 49%). The most commonly injured fingers were the third (27.2%), and second (25.8%). Eighty-seven percent of the patients presented with single-digit injuries. Fingertip amputations were the most common type of injury with 620 cases (49%), followed by simple fingertip lacerations (574 cases, 45%), and nail bed injuries in 71 cases (5.6%). Surgical management was necessary in 95.8% of the cases.

Conclusions: Fingertip injuries remain the most common reason for consultation in hand emergencies. A structured approach for their treatment is necessary to obtain the best clinical outcomes.

背景:指尖是上肢最常见的解剖结构损伤。这项工作的目的是提出我们的经验,在管理指尖损伤。方法:所有指尖损伤患者均由总医院整形与重建外科“Manuel Gea gonzalez医生”包括2010年7月至2015年6月在墨西哥的病例;描述了他们的人口统计学特征,以及伤害和管理模式。结果:共纳入1265例患者,其中75%为男性。平均发病年龄20.5±16.46岁;最常受影响的年龄组为15岁以下(46.7%)。右侧和左侧损伤几乎同样普遍(51%对49%)。最常见的手指损伤是第三指(27.2%)和第二指(25.8%)。87%的患者表现为个位数损伤。最常见的损伤类型是指截断620例(49%),其次是单纯性指裂伤574例(45%),甲床伤71例(5.6%)。95.8%的病例需要手术治疗。结论:指尖损伤仍是手部急诊问诊最常见的原因。为了获得最佳的临床结果,有必要采用结构化的治疗方法。
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引用次数: 1
Bone invasion by oral squamous cell carcinoma. 口腔鳞状细胞癌侵袭骨。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021139
David Král, Richard Pink, Lenka Šašková, Jaroslav Michálek, Peter Tvrdý

Background: With regards to the anatomical relationships in the mouth, oral squamous cell carcinoma can invade the maxilla or the mandible. According to the TNM system, tumours that invade through cortical bone are classified as T4a, stage IVA. Bone invasion by oral squamous cell carcinoma most often occurs in tumours close to the bone or in larger and more advanced tumours. It is considered an adverse prognostic factor and it is often a diagnostic and therapeutic problem. Destruction of the bone tissue is mediated by activated osteoclasts rather than directly by carcinoma. Tumor necrosis factors - receptor activator of NF-kB (RANK), receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) - play an important role in osteoclastogenesis. According to histological point of view, there are three patterns of bone invasion - erosive, mixed and infiltrative. The most commonly used imaging techniques when evaluating bone invasion by oral squamous cell carcinoma include CT and MRI.

Purpose: This review is focused on the cellular and molecular mechanisms, histological patterns and detection methods of bone invasion caused by oral squamous cell carcinoma.

背景:口腔鳞状细胞癌在口腔内的解剖关系,可侵犯上颌骨或下颌骨。根据TNM系统,通过骨皮质侵入的肿瘤被分类为T4a, IVA期。口腔鳞状细胞癌对骨骼的侵袭最常发生在靠近骨骼的肿瘤或更大、更晚期的肿瘤中。它被认为是一个不利的预后因素,它往往是一个诊断和治疗问题。骨组织的破坏是由活化的破骨细胞介导的,而不是由癌直接介导的。肿瘤坏死因子- NF-kB受体激活因子(RANK)、NF-kB配体受体激活因子(RANKL)和骨保护素(OPG)在破骨细胞发生中发挥重要作用。从组织学角度看,骨浸润可分为侵蚀型、混合型和浸润型三种。在评估口腔鳞状细胞癌对骨的侵袭时,最常用的成像技术包括CT和MRI。目的:综述口腔鳞状细胞癌致骨侵犯的细胞分子机制、组织学特征及检测方法。
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引用次数: 2
Surgical treatment and management of cutaneous squamous cell carcinoma in patients with dystrophic epidermolysis bullosa - a case report. 营养不良大疱性表皮松解症并发皮肤鳞状细胞癌的手术治疗及处理1例。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021196
P Rotschein, J Vokurková, H Bučková

Epidermolysis bullosa (EB) is a rare inherited disease which is characterized by blisters on the skin and mucous membranes. Some forms of EB are associated with a risk of squamous cell carcinoma (SCC) development, which, unlike in the general population, is formed at a young age. SCC is the most common cause of death in patients with a dystrophic form. It is necessary to examine chronic and non-healing wounds for an increased risk of SCC. The basic treatment consists of surgical excision of the tumor site with a wide margin into healthy tissue. The surgical wound can be healed by secondary intention to prevent further trauma of the patient. The radicality of the excision is influenced by the location of the tumor. On the body, it is considerably limited by the surrounding tissue; on the limb, it is necessary to consider its amputation. In case of dissemination of the disease, it is important to approach patients individually and discuss other treatment options, including palliative care, within the national EB Center. The therapy is focused on pain treatment, remedial surgical dressings and psychological support with an emphasis on maintaining the quality of life.

大疱性表皮松解症(EB)是一种罕见的遗传性疾病,其特征是皮肤和粘膜上出现水泡。某些形式的EB与鳞状细胞癌(SCC)发展的风险相关,与一般人群不同,鳞状细胞癌是在年轻时形成的。SCC是营养不良型患者最常见的死亡原因。有必要检查慢性和未愈合的伤口是否增加了SCC的风险。基本的治疗包括手术切除肿瘤部位与广泛的边缘到健康组织。手术创面可通过二次创面愈合,防止患者进一步外伤。切除的根治性受肿瘤位置的影响。在身体上,它受到周围组织的很大限制;在肢体上,有必要考虑它的截肢。在疾病传播的情况下,重要的是与患者单独接触,并在国家EB中心讨论其他治疗方案,包括姑息治疗。治疗的重点是疼痛治疗,手术敷料和心理支持,重点是维持生活质量。
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引用次数: 0
Combined fungal and bacterial infection in deep burns of the lower limb - a case report. 下肢深度烧伤并发真菌和细菌感染1例。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021201
I Tresnerová, M Fiamoli, B Lipový, J Bartošková

Fungal infections are one of the most common diseases. Superficial mycoses affect the skin and visible mucous membranes. Deep mycoses include organ and systemic mycoses. The incidence of these diseases is increasing due to the use of broad-spectrum antibiotics, corticosteroids and cytostatics. Mycoses (yeasts and filamentous fungi) occur more often in patients with burns than in other patients; especially in patients with large and deep extent burns. In this case report, we are presenting a case of a 62-year-old patient hospitalized at the Department of Burns and Plastic Surgery, University Hospital Brno, with extensive deep burns (2nd-4th degree) covering 35% total body surface area (TBSA), predominantly in both lower limbs. During hospitalization, the patient was diagnosed with a combined bacterial and fungal infection for which targeted therapy was indicated.

真菌感染是最常见的疾病之一。浅表真菌病影响皮肤和可见粘膜。深部真菌病包括器官真菌病和全身真菌病。由于使用广谱抗生素、皮质类固醇和细胞抑制剂,这些疾病的发病率正在增加。真菌病(酵母菌和丝状真菌)在烧伤患者中比在其他患者中更常见;尤其适用于大面积、深度烧伤患者。在本病例报告中,我们报告了一位62岁的布尔诺大学医院烧伤和整形外科住院的患者,其广泛的深度烧伤(2 -4度)覆盖了35%的体表面积(TBSA),主要发生在双下肢。在住院期间,患者被诊断为细菌和真菌联合感染,需要进行靶向治疗。
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引用次数: 0
Cyanide poisoning in patients with inhalation injury - the phantom menace. 吸入性损伤患者的氰化物中毒——幽灵的威胁。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021185
F Raška, B Lipový, M Hladík, J Holoubek

Inhalation injury is a serious complication in patients with burns that dramatically increases their morbidity and mortality. These patients are always suspected of having inhalation injury with potential intoxication. We usually encounter carbon monoxide intoxication, but it is necessary to think about the possibility of poisoning by other combustion products. Cyanide intoxications are less common, but their diagnosis and treatment are more complicated. The diagnosis can only be based on the history, clinical findings, and indirect laboratory signs. Direct determination of plasma cyanide levels is not generally adopted in routine clinical practice. Nowadays, several specific antidotes with different mechanisms of action are available. There are no clear guidelines on the antidote of choice, as the evidence base is limited by a lack of randomised controlled trials in humans. In two mini case reports, we present our experience with the diagnosis and therapy of patients with suspected cyanide poisoning.

吸入性损伤是烧伤患者的严重并发症,可显著增加其发病率和死亡率。这些病人常被怀疑有吸入性损伤和潜在的中毒。我们通常会遇到一氧化碳中毒,但要考虑到其他燃烧产物中毒的可能性。氰化物中毒不太常见,但其诊断和治疗更为复杂。诊断只能基于病史、临床表现和间接的实验室体征。在常规临床实践中,一般不采用直接测定血浆氰化物水平。目前已有几种具有不同作用机制的特异解毒剂。由于缺乏人体随机对照试验,证据基础有限,因此没有明确的解毒剂选择指南。在两个小病例报告中,我们介绍了我们对疑似氰化物中毒患者的诊断和治疗经验。
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引用次数: 0
Cooperation of the maxillofacial and plastic surgeon in reconstructive surgical procedures in gunshot injury - a case report. 颌面外科与整形外科在枪伤重建手术中的合作一例报告。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp2021190
D Hvizdoš, I Homola, D Statelová, M Janíčková, I Malachovský, K Mikušková

Lower and middle face defects resulting from gunshot wounds often cause severe functional and cosmetic deformities. The purpose of this case report is to refer to our experiences in the treatment of facial gunshot trauma associated with attempted suicide that resulted in a complex facial injury. The goal of the treatment of complex facial injuries is a proper reconstruction of the hard and soft tissue defects and sufficient rehabilitation of the relevant functions, such as speech, nutrition and appearance. A close cooperation of the maxillofacial and plastic surgeon is essential to achieve a satisfactory outcome.

由于枪伤造成的面部中下部缺损通常会导致严重的功能和美容畸形。本病例报告的目的是参考我们在面部枪伤相关的企图自杀导致复杂的面部损伤的治疗经验。复杂面部损伤的治疗目标是硬软组织缺损的适当重建和相关功能的充分恢复,如语言、营养和外观。颌面外科医生和整形外科医生的密切合作是取得满意结果的必要条件。
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引用次数: 1
Thirty-five years of the Department of Plastic Surgery and Burns Treatment at the University Hospital in Hradec Králové. 在赫拉德克大学医院整形外科和烧伤治疗科工作了35年Králové。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp202178
Leo Klein

Background: The Department of Plastic Surgery and Burns Treatment was established as a part of the newly created 2nd Department of Surgery of Charles University, Medical Faculty and the University Hospital in Hradec Králové in 1985. Through modest beginnings, activities of the Department expanded up to full coverage of specialized care in plastic surgery within the region with almost one million inhabitants.

Aim: In this article, the most important events of several historical phases related to almost four decades are described. The aspects of medical personnel, technological and space equipment are especially emphasized. The Department has always been working on the principles of interdisciplinary co-operation within the department itself and other departments within the hospital as well. Over the past 35 years, the Department of Plastic Surgery and Burns Treatment has been firmly entrenched in the spectrum of specialized activities of the University Hospital in Hradec Králové.

背景:1985年,查尔斯大学医学院和赫拉德克大学医院成立了整形外科和烧伤治疗科,作为新成立的第二外科的一部分。通过适度的开始,该部的活动扩大到在几乎有100万居民的区域内全面提供整形外科的专门护理。目的:在这篇文章中,描述了近四十年来几个历史阶段的最重要事件。特别强调医疗人员、技术和空间设备方面的问题。该科一直奉行跨学科合作的原则,并与本科及医院其他科室合作。在过去的35年里,整形外科和烧伤治疗科在赫拉德克大学医院Králové的专业活动中占有一席之地。
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引用次数: 0
Long-term donor-site morbidity after thumb reconstruction with twisted-toe technique. 扭转趾技术重建拇指后长期供区发病率。
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.48095/ccachp202146
Tomáš Kempný, Olga Košková, Karel Urbášek, Martin Zvonař, Kateřina Kolářová, Břetislav Lipový, Martin Knoz, Jakub Holoubek

Background: Traumatic thumb loss is a serious injury affecting patient´s ability to work and participate in activities of daily life. The main goal for a plastic surgeon is to restore hand grip, often by microsurgical methods. However, patients should be informed of all effects associated with tissue harvesting. The aim of the study was to assess the impact on donor foot and gait cycle in patients who have undergone thumb reconstruction using twisted-toe technique modified by Kempný.

Material and methods: Twelve patients participated in the study: all suffered a thumb loss between the years 2003 and 2011 and the twisted-toe technique for thumb reconstruction was utilized. The changes in foot pressure distribution and lower extremity joint loading were evaluated.

Results: The differences in total maximal plantar pressure, pressure time integral, contact area, and maximum force between the affected and non-affected foot were statistically significant (P 0.1). No significant differences of temporal gait parameters between the affected and non-affected extremity were observed; however, statistically significant differences in kinetics parameters, frontal ankle and knee moments were detected.

Conclusion: Donor limb functionality and anatomical disability were assessed using pedobarography systems and 3D-gait analysis. The recorded differences in plantar pressure distribution (increased pressure in I., IV. and V. metatarsal areas) and overload of the medial compartment of the knee joint were the most significant findings. Therefore, wearing individually adapted shoe insoles as prevention of osteoarthrosis might be beneficial for patients after thumb reconstruction by a twisted-toe technique.

背景:外伤性拇指丧失是一种严重影响患者工作能力和日常生活能力的损伤。整形外科医生的主要目标是恢复手部握力,通常采用显微外科手术方法。然而,患者应该被告知与组织采集相关的所有影响。该研究的目的是评估使用Kempný改良的扭转脚趾技术进行拇指重建的患者对供体足和步态周期的影响。材料与方法:12例患者参与研究,均为2003 - 2011年间拇指缺失,采用扭转趾技术重建拇指。评估足部压力分布和下肢关节负荷的变化。结果:患足与非患足在足底总最大压力、压力时间积分、接触面积、最大作用力方面差异均有统计学意义(p0.1)。受影响肢体和未受影响肢体的时间步态参数无显著差异;然而,在动力学参数、踝关节和膝关节前侧力矩方面存在统计学上的显著差异。结论:使用足镜系统和3d步态分析评估供体肢体功能和解剖残疾。记录的足底压力分布差异(I、iv、v跖区压力增加)和膝关节内侧腔室负荷过重是最显著的发现。因此,穿着单独适应的鞋垫来预防骨关节病可能对通过扭转脚趾技术重建拇指的患者有益。
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引用次数: 0
OPTIMAL INJECTION DEPTH FOR COLLAGENASE CLOSTRIDIUM HISTOLYTICUM DETERMINED BY ULTRASONOGRAPHY IN THE TREATMENT OF DUPUYTREN´S DISEASE. 超声确定溶组织梭菌胶原酶最佳注射深度治疗双胎病。
Q4 Medicine Pub Date : 2020-01-01
I Nagura, T Kanatani, Y Harada, A Inui, Y Mifune, R Kuroda, S Lucchina

Introduction: A non-surgical procedure for the treatment of Dupuytrens disease is a palmar injection of Collagenase Clostridium Histolyticum to the recommended depth of “around 2-3 mm”. However, there is little supporting evidence from the literature to substantiate this. The aim of this study was to evaluate the “optimal depth” for injection of Collagenase Clostridium Histolyticum by ultrasonography for the treatment of Dupuytrens disease.

Material and methods: A total of 43 patients were enrolled in this study. We marked the collagenase injection point on the skin above the cord before injection. We then measured the distance from the surface of the skin to the middle of the cord by ultrasonography long axis imaging and defined this as the “optimal depth”.

Results: The average depth from the skin to the centre of the cord was 2.4 mm. The average distance from the surface of the skin to the proximal surface of the cord was 1.0 mm and the average thickness of the cord was 2.7 mm.

Conclusion: By precise measurement of individual cases utilising ultrasonography we were able to confirm that the recommendations for injection depth as provided by the supplier of Collagenase Clostridium Histolyticum (2-3 mm) were in agreement with our findings. However no objective guide was supplied as with regards to interindividual variability between patients and we suggest that the use of preliminary ultrasonography will likely provide improved outcomes.

简介:治疗Dupuytrens病的一种非手术方法是掌部注射胶原酶溶组织梭菌至推荐深度约2-3 mm。然而,文献中几乎没有支持这一观点的证据。本研究的目的是评估最佳深度”超声观察注射溶组织梭菌胶原酶治疗多发性硬化症的疗效。材料与方法:共纳入43例患者。注射前我们在脊髓上方的皮肤上标记胶原酶注射点。然后,我们通过超声长轴成像测量皮肤表面到脐带中部的距离,并将其定义为最佳深度。结果:皮肤至脊髓中心的平均深度为2.4 mm。从皮肤表面到脊髓近端表面的平均距离为1.0 mm,脊髓的平均厚度为2.7 mm。结论:通过超声对个别病例的精确测量,我们能够确认胶原酶溶组织梭菌供应商提供的注射深度(2-3 mm)与我们的发现一致。然而,关于患者之间的个体差异,没有提供客观的指导,我们建议使用初步超声检查可能会改善结果。
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引用次数: 0
CURRENT OPTIONS IN PHARMACOLOGICAL INTERVENTIONS FOR MICROVASCULAR ANASTOMOSIS PATENCY: REVIEW. 目前微血管吻合通畅的药物干预方案:综述。
Q4 Medicine Pub Date : 2020-01-01
Š Pohanka, J Šimek

The key point for microvascular reconstruction is to preserve patency of flap vessels. Despite great improvement in reconstruction success rates in the last 30 years, ischemic complications are still an undesirable event. The authors assessed recent as well as older literature and compared progression in perioperative pharmacology interventions in antithrombotic prevention.

微血管重建的关键是保持皮瓣血管的通畅。尽管近30年来重建成功率有了很大的提高,但缺血性并发症仍然是一个不希望发生的事件。作者评估了最近和较早的文献,并比较了围手术期药物干预在抗血栓预防方面的进展。
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引用次数: 0
期刊
Acta chirurgiae plasticae
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