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Treatment options for infratemporal fossa tumors - case reports. 颞下窝肿瘤的治疗选择-病例报告。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp202568
S Kalmanová, V Čalkovský, P Hanzel, B Kolarovszki, R Richterová, K Adamicová, M Janíčková

Infratemporal fossa (ITF) tumors represent a group of tumors with complicated approach, due to specific anatomy of the space. The incidence is rare, but they always represent a challenge for choosing a treatment for each patient. We would like to present a few cases of ITF tumors treated in cooperation with our department to provide multiple views on this topic. In the presented cases, we used the open transmandibular approach, the endoscopic approach and the conservative approach in terms of patient observation.

颞下窝(ITF)肿瘤由于其特殊的解剖结构,是一组入路复杂的肿瘤。虽然发病率很低,但对于每位患者来说,选择合适的治疗方案总是一个挑战。在此,我们将介绍与我科合作治疗的几例ITF肿瘤,为大家提供关于这个话题的多种观点。在本病例中,我们采用了开放的经下颌入路、内窥镜入路和保守入路来观察患者。
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引用次数: 0
Editorial. 社论。
Q4 Medicine Pub Date : 2025-01-01
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引用次数: 0
A systematic review of the use of corticosteroid injections with and without local anaesthetic for trigger finger. 使用皮质类固醇注射与不局部麻醉扳机指的系统回顾。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp2025203
G J Hourston, K R Quinn, J Chan, A Mckee

Background: Trigger finger causes pain, catching, and locking of the finger, with corticosteroid injection being the first-line treatment. Injections with local anaesthetic may reduce immediate pain, but it has been suggested that added volume worsens pain. This systematic review aimed to evaluate studies investigating pain following corticosteroid injection for trigger finger, with or without local anaesthetic. Evaluation of the topic: We performed a prospectively registered systematic review (PROSPERO ID: CRD42024502361) following PRISMA guidelines. We searched PubMed, Cochrane Library, and Embase database for randomised trials or prospective cohort studies investigating pain following injection with corticosteroid with or without local anaesthetic. Patient demographic data, injection details and outcomes including visual analogue scale (VAS) pain scores were collected and summarised. Two articles including 98 patients (135 injections) were included. One article compared steroid injection with local anaesthetic and adrenaline to steroid injection with placebo (0.9% saline), and found that omitting local anaesthetic had a lower immediate VAS pain score (2.0 vs. 3.5; P < 0.01) however all injections contained the same volume. The second study measured VAS pain scores at multiple time points, and a recollection score for patients injected with either corticosteroid alone (1mL), corticosteroid and 1% xylocaine (2 mL), or corticosteroid and 0.9% saline (2 mL). VAS pain scores were similar in the steroid alone and steroid and local anaesthetic group at 1 minute post-injection and highest in the steroid and saline group. The local anaesthetic group had the lowest pain score 10 minutes post-injection. Meta-analysis of outcomes in these heterogeneously reported studies was not possible.

Conclusion: Corticosteroid injection for trigger finger varies considerably and outcomes are reported inconsistently. The evidence suggests that the addition of local anaesthetic may increase immediate pain due to volume effect or lowered pH but reduce early post-injection pain. Further well-designed randomised studies are needed to guide treatment decisions.

背景:扳机指引起疼痛、抓握和手指锁定,皮质类固醇注射是一线治疗方法。局部麻醉注射可能会减轻即时疼痛,但有人认为,增加剂量会加重疼痛。本系统综述旨在评价针对扳机指注射皮质类固醇后疼痛的研究,有或没有局部麻醉。主题评价:我们按照PRISMA指南进行了前瞻性注册系统评价(PROSPERO ID: CRD42024502361)。我们检索了PubMed、Cochrane图书馆和Embase数据库,寻找随机试验或前瞻性队列研究,以调查注射皮质类固醇伴或不伴局部麻醉后的疼痛。收集并总结患者人口统计数据、注射细节和结果,包括视觉模拟评分(VAS)疼痛评分。纳入两篇文章,共98例患者(135次注射)。一篇文章比较了局部麻醉和肾上腺素的类固醇注射与安慰剂(0.9%生理盐水)的类固醇注射,发现不局部麻醉的即时VAS疼痛评分较低(2.0比3.5;P < 0.01),但所有注射的体积相同。第二项研究测量了多个时间点的VAS疼痛评分,以及单独注射皮质类固醇(1mL)、皮质类固醇和1%木卡因(2ml)或皮质类固醇和0.9%生理盐水(2ml)的患者的回忆评分。注射后1分钟,单独使用类固醇组和类固醇加局麻组的VAS疼痛评分相似,类固醇加生理盐水组疼痛评分最高。局部麻醉组在注射后10分钟疼痛评分最低。不可能对这些异质性报告的研究结果进行荟萃分析。结论:皮质类固醇注射治疗扳机指差异很大,结果报告不一致。有证据表明,局部麻醉剂的加入可能会由于体积效应或降低pH值而增加即时疼痛,但会减轻早期注射后疼痛。需要进一步精心设计的随机研究来指导治疗决策。
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引用次数: 0
Editorial. 社论。
Q4 Medicine Pub Date : 2025-01-01
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引用次数: 0
Risk factors for cleft lip and palate in the Czech population - a double center study. 捷克人口中唇腭裂的危险因素——双中心研究。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp202592
W Urbanová-, M Večeřová, J Vokurková, L Streit, J Vašáková-, A Leger, O Košková

Background: Orofacial clefts (OFC) are common congenital anomalies with complex genetic and environmental etiologies. Although multiple risk factors have been suggested, their role in cleft type and severity remains unclear.

Objective: This study aimed to assess the relationship between environmental and maternal health factors (body mass index - BMI, parental age, infection, stress, prenatal vitamin supplementation) and the occurrence and severity of cleft types in the Czech population, as well as the effectiveness of prenatal diagnosis by ultrasound.

Methods: A total of 96 parents of children with nonsyndromic OFC born between 2017 and 2024 in the Czech Republic were surveyed using a custom online questionnaire (RoRis). The data were analyzed using Fisher's exact test (a = 0.05).

Results: The distribution of cleft types in this Czech sample was consistent with international data. Prenatal diagnosis by ultrasound was established in 55% of cases. The highest detection rates were observed for bilateral cleft lip and palate, with 100% of cases diagnosed prenatally, and for unilateral cleft lip and palate, with a 93% detection rate. In contrast, cleft palate only (CPO) was the most frequently missed, with 88% of cases undetected. No significant associations were found neither between the cleft type nor the severity of clefts and parental age, maternal BMI, medication use, infection with fever, or stress during pregnancy. Most mothers had a normal BMI (51%), and 85% reported prenatal supplement use. COVID-19 infection during pregnancy was reported in 13 cases, but no clear link with cleft severity was found.

Conclusion: While several exogenous factors were studied, no significant associations neither with cleft type nor severity were found. The study highlights the limitations of prenatal screening diagnosis by ultrasound, particularly for CPO, and supports the need for further research into modifiable risk factors.

背景:口面裂(OFC)是一种常见的先天性异常,具有复杂的遗传和环境病因。尽管多种危险因素已被提出,但它们在唇裂类型和严重程度中的作用仍不清楚。目的:本研究旨在评估捷克人群中环境和孕产妇健康因素(体重指数- BMI、父母年龄、感染、压力、产前维生素补充)与唇裂类型发生和严重程度的关系,以及产前超声诊断的有效性。方法:采用定制在线问卷(RoRis)对捷克共和国2017年至2024年出生的96名非综合征性OFC儿童的父母进行调查。采用Fisher精确检验对数据进行分析(a = 0.05)。结果:捷克样本的唇裂类型分布与国际数据一致。产前超声诊断成功率为55%。双侧唇腭裂的检出率最高,产前诊断率为100%,单侧唇腭裂的检出率为93%。相比之下,单纯腭裂(CPO)是最常见的漏诊,88%的病例未被发现。没有发现唇裂类型和严重程度与父母年龄、母亲体重指数、药物使用、感染发烧或怀孕期间的压力有显著关联。大多数母亲的身体质量指数正常(51%),85%的母亲报告产前服用了补充剂。据报道,怀孕期间感染COVID-19的病例有13例,但未发现与唇裂严重程度有明确联系。结论:虽然研究了几种外源性因素,但没有发现与唇裂类型和严重程度有显著相关性。该研究强调了超声产前筛查诊断的局限性,特别是对CPO,并支持对可改变的危险因素进行进一步研究的必要性。
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引用次数: 0
Brachymetacarpia - our experience with internal device for distraction osteogenesis in adolescent patients. 掌心短促:青少年患者牵张成骨内装置的应用经验。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp2025150
O Brychcí, A Schmoranzová

Background: Brachymetacarpia is a rare deformity characterized by shortening of one or more metacarpals, most commonly the fourth. This study aimed to evaluate the outcomes of surgical treatment for brachymetacarpia using an internal mini distractor and to compare its advantages over external fixators and other surgical techniques.

Materials and methods: We retrospectively analyzed 9 patients treated between 2011 and 2021 using gradual distraction osteogenesis with an internal mini distractor. Evaluated parameters included pre- and postoperative metacarpal lengths, deviation from ideal length, complications, treatment duration, and patient satisfaction.

Results: The mean lengthening was 1.2 cm (range 0.7-1.5 cm), with minimal deviation from the ideal metacarpal length (+0.3 cm on average). The average distraction period was 68 days. Minor complications occurred in 3 patients, including synovitis and delayed consolidation, all managed successfully. Functional outcomes and patient satisfaction were uniformly excellent.

Conclusion: The internal distraction system provides a reliable, safe, and patient-friendly method for metacarpal lengthening. Compared to external fixators, it offers superior stability, reduced the risk of infection, and improved aesthetic and functional outcomes in selected cases.

背景:掌骨短缩是一种罕见的畸形,其特征是一个或多个掌骨缩短,最常见的是第四掌骨。本研究旨在评估使用内微型牵张器治疗掌骨短距离的手术效果,并比较其相对于外固定架和其他手术技术的优势。材料和方法:我们回顾性分析了2011年至2021年间使用内微型牵张器渐进牵张成骨的9例患者。评估参数包括术前和术后掌骨长度、与理想长度的偏差、并发症、治疗持续时间和患者满意度。结果:平均延长1.2 cm(范围0.7-1.5 cm),与理想掌骨长度(平均+0.3 cm)偏差最小。平均分心时间为68天。3例患者出现滑膜炎、延迟实变等轻微并发症,均成功处理。功能结果和患者满意度均非常好。结论:内牵开系统是一种可靠、安全、对患者友好的掌骨延长方法。与外固定架相比,它提供了更好的稳定性,降低了感染的风险,并改善了某些病例的美观和功能结果。
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引用次数: 0
Elevation of vitamin B12 levels attributed to biopolymer implants - a case report. 生物聚合物植入物导致维生素B12水平升高-一例报告。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp202564
J A Avila Rueda, A Hurtado-Ortiz, M Licht-Ardila, G Camelo-Pardo, A Mendoza-Monsalve, E F Manrique-Hernández

A 62-year-old female patient with no relevant medical history presented with elevated vitamin B12 levels, which were incidentally detected during a routine examination. Comprehensive evaluations excluded oncohematological disorders, liver diseases, pulmonary conditions, viral infections, autoimmune disorders, and cardiovascular causes, as well as paradoxical increases in vitamin B12 levels. It was hypothesized that the elevated vitamin B12 levels were related to a chronic inflammatory process, potentially exacerbated by the presence of biopolymers. Given the improvement in symptoms and the risks associated with implant removal, it was decided to proceed with semi-annual clinical monitoring, with surgical intervention considered only if clinical abnormalities or significant changes in imaging were observed.

62岁女性患者,无相关病史,在常规检查中偶然发现维生素B12水平升高。综合评估排除了血液肿瘤疾病、肝脏疾病、肺部疾病、病毒感染、自身免疫性疾病和心血管疾病,以及维生素B12水平的矛盾增加。据推测,维生素B12水平的升高与慢性炎症过程有关,可能因生物聚合物的存在而加剧。鉴于症状的改善和植入物移除相关的风险,我们决定进行半年一次的临床监测,只有在观察到临床异常或影像学发生重大变化时才考虑手术干预。
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引用次数: 0
Possibilities of intranasal reconstruction in complex nasal defects. 复杂鼻缺损鼻内重建的可能性。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp202527
Z Dvořák, M Kubát, A Berkeš, R Pink, T Kubek, J Menoušek

Background: Complex nasal defects most often arise due to oncological resection or severe trauma. Traditional methods of two-stage nose reconstruction using a forehead flap with a skin graft have often resulted in collapse and deformity of the nose with a very compromised outcome over time. These techniques were gradually replaced by new procedures consistently reconstructing the intranasal lining, most often with flaps from the nasal septum. These methods reconstruct the cartilaginous and bony support of the nose as well, while the skin cover of the nose is, nowadays, in large defects, reconstructed in three stages. Evaluation of the topic: The options for intranasal lining reconstruction are as follows: a composite graft, a turnover flap covered with a local flap, advancement of the residual lining (bipedicle vestibular mucosa flap), a folded forehead flap, a prelaminated forehead flap, the use of another local flap (a forehead, nasolabial, facial artery myomucosal flap), a hinged turnover flap, a septal mucoperichondrial hinged flap, a composite septal chondromucosal pivot flap, a turbinate flap and microvascular free flaps (a radial forearm flap, a helix free flap, a kite flap, a dorsalis pedis free flap, a temporoparietal free flap, a postauricular free flap). Thanks to the abundant vascular supply of the face, the risk of ischemia and infection is mitigated, allowing most complex nasal defects to be reconstructed by using local flaps to restore all layers of the nose. Local tissues retain ideal quality, coloration, and texture, are reliable, and usually result in esthetically acceptable morbidity of the donor area. If the inner lining defect is extensive, it must be reconstructed by free microvascular tissue transfer. If other than intranasal flaps are used in the reconstruction of the internal lining, it is preferable to postpone the reconstruction of the supporting framework until the second stage while thinning the flaps used; otherwise, there is a high risk of obturation of the nasal airways.

Conclusion: The results of modern reconstruction dramatically improved after the introduction of three-stage nasal reconstruction and emphasizing the reconstruction of all layers of the nose. Therefore, a quality inner lining is the basis for the construction of the new nose.

背景:复杂的鼻缺损多因肿瘤切除或严重外伤引起。传统的两阶段鼻子重建方法使用前额皮瓣和皮肤移植物,经常导致鼻子塌陷和畸形,随着时间的推移,结果非常不利。这些技术逐渐被持续重建鼻内内膜的新手术所取代,最常使用鼻中隔皮瓣。这些方法也重建了鼻子的软骨和骨支撑,而现在鼻子的皮肤覆盖在较大的缺陷中,分为三个阶段重建。主题评价:鼻内衬里重建的选择如下:复合移植物,局部皮瓣覆盖的翻转皮瓣,残余衬里推进(双蒂前庭粘膜皮瓣),折叠前额皮瓣,预层压前额皮瓣,使用另一个局部皮瓣(前额,鼻唇,面动脉肌粘膜皮瓣),铰链翻转皮瓣,中隔粘骨膜铰链皮瓣,复合中隔软骨粘膜枢轴皮瓣,鼻甲皮瓣和微血管自由皮瓣(桡骨前臂皮瓣,螺旋自由皮瓣,kite皮瓣),足背游离皮瓣,颞顶骨游离皮瓣,耳后游离皮瓣)。由于面部丰富的血管供应,减少了缺血和感染的风险,允许使用局部皮瓣修复鼻子的所有层来重建大多数复杂的鼻缺损。局部组织保持理想的质量,颜色和质地,是可靠的,通常导致美观可接受的供体区发病率。如果内层缺损广泛,则必须通过游离微血管组织移植重建。如果使用鼻内瓣以外的皮瓣重建内层,最好将支撑框架的重建推迟到第二阶段,同时稀释所使用的皮瓣;否则,鼻道堵塞的风险很高。结论:引入三段式鼻部重建术,强调鼻部各层重建术后,现代鼻部重建术的效果显著提高。因此,一个高质量的内衬是构建新鼻子的基础。
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引用次数: 0
Mini-invasive temporalis muscle tendon transfer and lengthening temporalis myoplasty for facial reanimation - a retrospective outcome analysis. 微创颞肌肌腱转移和延长颞肌成形术治疗面部再生-回顾性结果分析。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp202582
J Macek, N Dubovská, K C Bayezid, L Streit
<p><strong>Background: </strong>Long-standing facial nerve paralysis leads to profound functional, aesthetic, social, and psychological impairments, significantly reducing patients' quality of life (QOL). Lengthening temporalis myoplasty and mini-invasive temporalis muscle tendon transfer are considered standard treatment options for dynamic facial reanimation in patients with flaccid facial paralysis, particularly in patients for whom more extensive free functional muscle transfers may not be suitable. The aim of this study was to retrospectively evaluate these two temporalis muscle-based reanimation techniques in an institutional patient cohort, as there is a lack of comparative studies addressing their outcomes.</p><p><strong>Methods: </strong>Between 2015 and 2021, 23 patients with long-standing (>18 months) flaccid facial palsy underwent dynamic reanimation surgery using either lengthening temporalis myoplasty (N = 8) or mini-invasive temporalis muscle tendon transfer (N = 15). Patient selection favoured local transfers in older or comorbid patients or when cross--facial nerve grafts were contraindicated. Many patients also underwent adjunctive static procedures, such as nasal ala suspension (N = 7) and/or lagophthalmos correction (N = 17). Postoperative physiotherapy employed the Mirror-effect protocol to improve muscle control and smiling ability. Outcomes were assessed pre-and postoperatively using clinician-reported House-Brackmann (HB) and eFACE scores, as well as the patient-reported Facial Palsy Disability Questionnaire (FPDQ). Statistical analysis was conducted using the Wilcoxon paired test and Fisher's exact test (significance P < 0.05).</p><p><strong>Results: </strong>The mean patient age was 54.4 years (SD = 16.1), with 15 females and 8 males. The average follow-up to stable surgical results was 10.6 months (SD = 7.8). For the mini-invasive temporalis muscle tendon transfer group (N = 15), mean improvements were observed as follows: 1.6 HB points (SD = 0.6), 34.1% eFACE static (SD = 14.1), 28.1% eFACE dynamic (SD = 19.0), and 34.2% FPDQ overall score (SD = 11.3), with total of 3 revisions performed. For the temporalis myoplasty group (N = 8), mean improvements were 1.6 HB points (SD = 0.7), 27.4% eFACE static (SD = 18.6), 33.3% eFACE dynamic (SD = 17.2), and 26.2% FPDQ overall (SD = 15.7), with one revision surgery performed. No statistically significant difference in outcome was found between the two surgical techniques.</p><p><strong>Conclusions: </strong>Both surgical techniques for facial reanimation evaluated in this study - the lengthening temporalis myoplasty and the minimally invasive temporalis tendon transfer -demonstrated significant improvements in clinician-graded facial function and QOL outcomes. Although the minimally invasive technique required a less extensive surgical field in the temporal area, it required additional graft harvesting and was associated with a slightly increased risk of revision surgery. A
背景:长期面神经麻痹会导致严重的功能、审美、社交和心理障碍,显著降低患者的生活质量。延长颞肌成形术和微创颞肌肌腱移植被认为是弛缓性面瘫患者动态面部再生的标准治疗选择,特别是对于那些可能不适合进行更广泛的自由功能肌肉移植的患者。由于缺乏针对其结果的比较研究,本研究的目的是在一个机构患者队列中回顾性评估这两种基于颞肌的再生技术。方法:2015年至2021年,23例长期(18个月)的弛缓性面瘫患者采用延长颞肌成形术(N = 8)或微创颞肌肌腱转移(N = 15)进行动态再生手术。老年人或合并症患者或交叉面神经移植禁忌时,患者选择偏向局部移植。许多患者还接受了辅助静态手术,如鼻翼悬吊术(N = 7)和/或眼球lagophthalmo矫正术(N = 17)。术后物理治疗采用镜像效应方案,改善肌肉控制和微笑能力。使用临床报告的House-Brackmann (HB)和eFACE评分以及患者报告的面瘫残疾问卷(FPDQ)评估术前和术后的结果。统计学分析采用Wilcoxon配对检验和Fisher确切检验(P < 0.05)。结果:患者平均年龄54.4岁(SD = 16.1),其中女性15例,男性8例。平均随访时间为10.6个月(SD = 7.8)。对于微创颞肌肌腱转移组(N = 15),平均改善如下:1.6 HB分(SD = 0.6), 34.1%的eFACE静态(SD = 14.1), 28.1%的eFACE动态(SD = 19.0), 34.2%的FPDQ总分(SD = 11.3),共进行了3次修改。对于颞肌成形术组(N = 8),平均改善1.6 HB点(SD = 0.7),静态eFACE 27.4% (SD = 18.6),动态eFACE 33.3% (SD = 17.2),总体FPDQ 26.2% (SD = 15.7),进行了一次翻修手术。两种手术方式的预后无统计学差异。结论:本研究评估的两种面部再生手术技术-延长颞肌成形术和微创颞肌肌腱转移-在临床分级的面部功能和生活质量结果方面都有显着改善。虽然微创技术需要的颞区手术范围较小,但它需要额外的移植物收获,并且与翻修手术的风险略有增加有关。本研究的一个局限性是每组患者数量相对较少,强调需要前瞻性和/或多中心研究来验证和确认我们的发现。
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引用次数: 0
Experience with pediatric and adult cases of ambiguous genitalia reconstructed with a single stage feminizing genitoplasty procedure. 用单阶段女性化生殖器成形术重建儿童和成人生殖器模糊病例的经验。
Q4 Medicine Pub Date : 2025-01-01 DOI: 10.48095/ccachp20256
N Paul, S Adhikari

Background: The surgical procedure of feminizing genitoplasty aims at restoration of normal anatomy and function in various cases of disorders of sexual development with ambiguous genitalia.

Material and methods: Between April 2021 and May 2023, 23 patients underwent a single stage feminizing genitoplasty procedure at the department of plastic and reconstructive surgery. All the patients underwent clitoroplasty with partial glans preservation, omega flap vaginoplasty and labioplasty. Cases with only clitoroplasty were excluded from the study. Of these 23 patients, 17 had congenital adrenal hyperplasia and the rest 6 had varying degrees of androgen insensitivity syndrome. The age of the patients ranged from 4 to 23 years and all were raised as females. The mean operating time was around 120 to 150 minutes and average hospitalization period was 7 to 8 days. At follow-up evaluation, no major complications were observed. In all cases the vaginal introitus was located in the physiological position and was of varying size and elastic.

Conclusion: This procedure of single stage feminizing genitoplasty enables reconstruction with good cosmetic and functional results not only in children but also in adults presenting with ambiguous genitalia.

背景:女性化生殖器成形术的目的是恢复正常解剖和功能的各种情况下的性发育障碍与模糊的生殖器。材料和方法:在2021年4月至2023年5月期间,23名患者在整形和重建外科接受了单阶段女性化生殖器成形术。所有患者均行保留部分龟头的阴蒂成形术、阴道瓣成形术和阴唇成形术。仅阴蒂成形术的病例被排除在研究之外。23例患者中,17例有先天性肾上腺增生,6例有不同程度的雄激素不敏感综合征。患者年龄4 ~ 23岁,均为女性。平均手术时间120 ~ 150分钟,平均住院时间7 ~ 8天。在随访评估中,未观察到重大并发症。在所有病例中,阴道开口位于生理位置,大小和弹性各不相同。结论:单期女性化生殖器成形术不仅对儿童,而且对出现生殖器模糊的成人,都能获得良好的美容和功能效果。
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引用次数: 0
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Acta chirurgiae plasticae
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