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Predicting posthospitalization falls in Brazilian older adults: External validation of the Carpenter instrument. 巴西老年人住院后跌倒的预测:Carpenter工具的外部验证。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-07 DOI: 10.1111/acem.14888
Pedro K Curiati, Marcela Dos S Arruda, Christopher R Carpenter, Christian V Morinaga, Hugo M A Melo, Thiago J Avelino-Silva, Marlon R Aliberti

Objectives: This study sought to explore and externally validate the Carpenter instrument's efficacy in predicting postdischarge fall risk among older adults admitted to the emergency department (ED) for reasons other than falls or related injuries.

Methods: A prospective cohort study was conducted on 779 patients aged ≥ 65 years from a tertiary hospital in São Paulo, Brazil, who were monitored for up to 6 months post-ED hospitalization. The Carpenter instrument, which evaluates the four risk factors nonhealing foot sores, self-reported depression, inability to self-clip toenails, and prior falls, was utilized to assess fall risk. Follow-up by telephone occurred at 30, 90, and 180 days to identify falls and mortality. Fine-Gray models estimated the predictive power of Carpenter instrument for future falls, considering death as a competing event and sociodemographic factors, frail status, and clinical measures as confounders.

Results: Among 779 patients, 68 (9%) experienced a fall within 180 days post-ED admission, and 88 (11%) died. The majority were male (54%), with a mean age of 79 years. Upon utilizing the Carpenter score, those with a higher fall risk (≥2 points) displayed more comorbidities, greater frailty, and increased clinical severity at baseline. Regression analyses showed that every additional point on the Carpenter score increased the hazard of falls by 73%. Two primary contributors to its predictive potential were identified: a history of falls in the preceding year and an inability to self-clip toenails. However, the instrument's discriminative accuracy was suboptimal, with an area under the curve of 0.62.

Conclusions: While the Carpenter instrument associated with a higher 6-month postadmission fall risk among older adults post-ED visit, its accuracy for individual patient decision making was limited. Given the significant impact of falls on health outcomes and health care costs, refining risk assessment tools remains essential. Future research should focus on enhancing these assessments and devising targeted proactive strategies.

研究目的:本研究旨在探索并从外部验证 Carpenter 工具在预测因跌倒或相关伤害以外的原因而入住急诊科(ED)的老年人出院后跌倒风险方面的有效性:对巴西圣保罗一家三甲医院的 779 名年龄≥ 65 岁的患者进行了前瞻性队列研究,这些患者在急诊科住院后接受了长达 6 个月的监测。Carpenter 工具用于评估跌倒风险,该工具评估了足部溃疡不愈合、自我报告的抑郁、无法自行夹脚趾甲和之前跌倒这四个风险因素。在 30 天、90 天和 180 天进行电话随访,以确定跌倒和死亡率。Fine-Gray 模型估算了 Carpenter 工具对未来跌倒的预测能力,将死亡作为竞争事件,将社会人口因素、虚弱状态和临床指标作为混杂因素:在 779 名患者中,有 68 人(9%)在入院后 180 天内跌倒,88 人(11%)死亡。大多数患者为男性(54%),平均年龄为 79 岁。根据卡朋特评分,跌倒风险较高(≥2 分)的患者在基线时有更多的合并症、更虚弱、临床严重程度更高。回归分析表明,卡彭特评分每增加一分,跌倒风险就会增加 73%。卡彭特评分的预测潜力主要取决于两个因素:前一年的跌倒史和无法自行夹脚趾甲。然而,该工具的判别准确性并不理想,曲线下面积为 0.62:虽然 Carpenter 工具与老年人在急诊就诊后 6 个月内跌倒风险较高有关,但其对患者个人决策的准确性有限。鉴于跌倒对健康结果和医疗成本的重大影响,完善风险评估工具仍然至关重要。未来的研究应侧重于加强这些评估并制定有针对性的前瞻性策略。
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引用次数: 0
Emergency department usage of sugammadex in a large regional health system. 一个大型地区医疗系统急诊科使用舒降之定的情况。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-01-23 DOI: 10.1111/acem.14856
Paul S Jansson, Marc P T Pimentel, Raghu R Seethala
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引用次数: 0
The association of prehospital systemic corticosteroids with emergency department and in-hospital outcomes for patients with asthma exacerbations. 入院前全身使用皮质类固醇与哮喘加重患者在急诊科和住院期间的治疗效果之间的关系。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-08 DOI: 10.1111/acem.14890
Sriram Ramgopal, Vishal V Naik, Sho Komukai, Sylvia Owusu-Ansah, Remle P Crowe, Masashi Okubo, Christian Martin-Gill

Background: Timely administration of systemic corticosteroids is a cornerstone of asthma exacerbation treatment, yet little is known regarding potential benefits of prehospital administration by emergency medical services (EMS) clinicians. We examined factors associated with prehospital corticosteroid administration with hospitalization and hospital length of stay (LOS).

Methods: We performed a retrospective study of EMS encounters for patients 2-50 years of age with suspected asthma exacerbation from a national data set. We evaluated factors associated with systemic corticosteroid administration using generalized estimating equations. We performed propensity matching based on service level, age, encounter duration, vital signs, and treatments to evaluate the association of prehospital corticosteroid administration with hospitalization and LOS using weighted logistic regression. We evaluated the association of prehospital corticosteroid administration with admission using Bayesian models.

Results: Of 15,834 encounters, 4731 (29.9%) received prehospital systemic corticosteroids. Administration of corticosteroids was associated with older age; sex; urbanicity; advanced life support provider; vital sign instability; increasing doses of albuterol; and provision of ipratropium bromide, magnesium, epinephrine, and supplementary oxygen. Within the matched sample, prehospital corticosteroids were not associated with hospitalization (odds ratio [OR] 0.86, 95% confidence interval [CI] 0.73-1.01) or LOS (multiplier 0.76, 95% CI 0.56-1.05). Administration of corticosteroids was associated with lower odds of admission and shorter LOS in longer EMS encounters (>34 min), lower admission odds in patients with documented wheezing, and shorter LOS among patients treated with albuterol. In a Bayesian model with noninformative priors, the OR for admission among encounters given corticosteroids was 0.86 (95% credible interval 0.77-0.96).

Conclusions: Prehospital systemic corticosteroid administration was not associated with hospitalization or LOS in the overall cohort of asthma patients treated by EMS, though they had a lower probability of admission within Bayesian models. Improved outcomes were noted among subgroups of longer EMS encounters, documented wheezing, and receipt of albuterol.

背景:及时使用全身性皮质类固醇是治疗哮喘加重的基石,但人们对急救医疗服务(EMS)临床医生院前使用皮质类固醇的潜在益处知之甚少。我们研究了院前使用皮质类固醇与住院和住院时间(LOS)的相关因素:我们对全国数据集中 2-50 岁疑似哮喘加重患者的急救服务接诊情况进行了回顾性研究。我们使用广义估计方程评估了与全身使用皮质类固醇相关的因素。我们根据服务水平、年龄、就诊时间、生命体征和治疗方法进行倾向匹配,使用加权逻辑回归评估院前使用皮质类固醇与住院和 LOS 的关系。我们使用贝叶斯模型评估了院前使用皮质类固醇与入院的关系:在 15834 次就诊中,4731 人(29.9%)接受了院前全身皮质类固醇治疗。皮质类固醇的使用与年龄、性别、城市化程度、高级生命支持提供者、生命体征不稳定、阿布特罗剂量增加、异丙托溴铵、镁、肾上腺素和辅助供氧有关。在匹配样本中,院前皮质类固醇与住院(几率比 [OR] 0.86,95% 置信区间 [CI] 0.73-1.01)或 LOS(乘数 0.76,95% 置信区间 0.56-1.05)无关。在急救时间较长(>34 分钟)的患者中,使用皮质类固醇与较低的入院几率和较短的 LOS 相关,在有喘息记录的患者中,使用皮质类固醇与较低的入院几率相关,而在使用阿布特罗治疗的患者中,使用皮质类固醇与较短的 LOS 相关。在非信息先验的贝叶斯模型中,使用皮质类固醇治疗的患者入院几率为 0.86(95% 可信区间为 0.77-0.96):结论:在接受急救医疗服务的哮喘患者总体队列中,院前全身使用皮质类固醇与住院或住院时间无关,尽管在贝叶斯模型中他们入院的概率较低。在急救时间较长、有喘息记录和接受过盐酸克仑特罗治疗的亚组中,治疗效果有所改善。
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引用次数: 0
Prospective evaluation of single-dose aminoglycosides for treatment of complicated cystitis in the emergency department. 对急诊科单剂量氨基糖苷类药物治疗复杂性膀胱炎的前瞻性评估。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-06-18 DOI: 10.1111/acem.14924
Jianwei Pan, Menglu Zhu, Zhujin Song
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引用次数: 0
Malignant spinal cord compression: Atypical presentation, false localizing signs, time course, and implications for the emergency physician. 恶性脊髓压迫症:非典型表现、假性定位体征、时间过程以及对急诊科医生的影响。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-09 DOI: 10.1111/acem.14855
Anastasios Georgiou, Adam Farmer, Loukas Georgiou, Brian Walker
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引用次数: 0
Patient perceptions of behavioral flags in the emergency department: A qualitative analysis. 患者对急诊科行为标志的看法:定性分析。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-21 DOI: 10.1111/acem.14887
Rachel E Gonzales, Emily F Seeburger, Ari B Friedman, Anish K Agarwal

Background: To combat increasing levels of violence in the emergency department (ED), hospitals have implemented several safety measures, including behavioral flags. These electronic health record (EHR)-based notifications alert future clinicians of past incidents of potentially threatening patient behavior, but observed racial disparities in their placement may unintentionally introduce bias in patient care. Little is known about how patients perceive these flags and the disparities that have been found in their placement.

Objective: This study aims to investigate patient perceptions and perceived benefits and harms associated with the use of behavioral flags.

Methods: Twenty-five semistructured qualitative interviews were conducted with a convenience sample of patients in the ED of a large, urban, academic medical center who did not have a behavioral flag in their EHR. Interviews lasted 10-20 min and were recorded then transcribed. Thematic analysis of deidentified transcripts took place in NVivo 20 software (QSR International) using a general inductive approach.

Results: Participant perceptions of behavioral flags varied, with both positive and negative opinions being shared. Five key themes, each with subthemes, were identified: (1) benefits of behavioral flags, (2) concerns and potential harms of flags, (3) transparency with patients, (4) equity, and (5) ideas for improvement.

Conclusions: Patient perspectives on the use of behavioral flags in the ED vary. While many saw flags as a helpful tool to mitigate violence, concerns around negative impacts on care, transparency, and equity were also shared. Insights from this stakeholder perspective may allow for health systems to make flags more effective without compromising equity or patient ideals.

背景:为应对急诊科(ED)中日益严重的暴力事件,医院实施了多项安全措施,其中包括行为标记。这些基于电子健康记录(EHR)的通知会提醒未来的临床医生注意过去发生的具有潜在威胁性的患者行为事件,但观察到的标记位置的种族差异可能会无意中在患者护理中引入偏见。关于患者如何看待这些标记以及在标记位置上发现的差异,人们知之甚少:本研究旨在调查患者对使用行为标记的看法以及与之相关的利益和危害:对一家大型城市学术医疗中心急诊室的患者进行了 25 次半结构化定性访谈,这些患者的电子病历中没有行为标志。访谈持续了 10-20 分钟,并进行了录音和转录。采用一般归纳法,在 NVivo 20 软件(QSR International)中对去标识的记录誊本进行了主题分析:结果:参与者对行为旗的看法各不相同,既有积极的看法,也有消极的看法。我们确定了五个关键主题,每个主题都有副主题:(1) 行为标记的益处,(2) 标记的顾虑和潜在危害,(3) 对患者的透明度,(4) 公平性,以及 (5) 改进意见:患者对在急诊室使用行为标记的看法各不相同。虽然许多人认为行为标记是减少暴力的有用工具,但也有人担心会对护理、透明度和公平性产生负面影响。从这些利益相关者的角度出发,医疗系统可以在不损害公平性或患者理想的前提下,使标记更加有效。
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引用次数: 0
A death with a plan. 有计划的死亡
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-22 DOI: 10.1111/acem.14876
Zhaohui Su
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引用次数: 0
Gender and emergency physicians' experiences of leading decision making about restraint use: A qualitative study. 性别与急诊医生在领导使用限制措施的决策过程中的经历:定性研究。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-09 DOI: 10.1111/acem.14851
Anita Chary, Beatrice Torres, Elise Brickhouse, Datonye Charles, Ynhi Thomas, Michelle Suh
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引用次数: 0
Epidemiology of brief resolved unexplained events and impact of clinical practice guidelines in general and pediatric emergency departments. 简短解决不明原因事件的流行病学以及临床实践指南对普通科室和儿科急诊室的影响。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-01 DOI: 10.1111/acem.14881
Nassr Nama, Amy M DeLaroche, Mark I Neuman, Manoj K Mittal, Bruce E Herman, Daniela Hochreiter, Ron L Kaplan, Allayne Stephans, Joel S Tieder

Objectives: The aim of this study was to describe the incidence of brief resolved unexplained events (BRUEs) and compare the impact of a national clinical practice guideline (CPG) on admission and diagnostic testing practices between general and pediatric emergency departments (EDs).

Methods: Using the Nationwide Emergency Department Sample for 2012-2019, we conducted a cross-sectional study of children <1 year of age with an International Classification of Diseases diagnostic code for BRUE. Population incidence rate was estimated using Centers for Disease Control and Prevention birth data. ED incidence rate was estimated for all ED encounters. We used interrupted time series to evaluate the associated impact of the CPG publication on the outcomes of ED disposition (discharge, admission, and transfer) and electrocardiogram (ECG) use.

Results: Of 133,972 encounters for BRUE, 80.0% occurred in general EDs. BRUE population incidence was 4.28 per 1000 live births and the annual incidence remained stable (p = 0.19). BRUE ED incidence was 5.06 per 1000 infant ED encounters (p = 0.14). The impact of the BRUE CPG on admission rates was limited to pediatric EDs (level shift -23.3%, p = 0.002). Transfers from general EDs did not change with the CPG (level shift 2.2%, p = 0.17). After the CPG was published, ECGs increased by 13.7% in pediatric EDs (p = 0.005) but did not change in general EDs (level shift -0.2%, p = 0.82).

Conclusions: BRUEs remain a common pediatric problem at a population level and in EDs. Although a disproportionate number of infants present to general EDs, there is differential uptake of the CPG recommendations between pediatric and general EDs. These findings may support quality improvement opportunities aimed at improving care for these infants and decreasing unnecessary hospital admissions or transfers.

研究目的本研究旨在描述短暂缓解的不明原因事件(BRUE)的发生率,并比较国家临床实践指南(CPG)对普通急诊科和儿科急诊科入院和诊断检测做法的影响:方法: 我们利用 2012-2019 年全国急诊科样本,对儿童进行了一项横断面研究:在 133,972 例 BRUE 患者中,80.0% 在普通急诊科就诊。BRUE人群发病率为每千名活产婴儿4.28例,年发病率保持稳定(p = 0.19)。每 1000 例婴儿中,BRUE 急诊室发病率为 5.06 例(p = 0.14)。BRUE CPG 对入院率的影响仅限于儿科急诊室(水平变化-23.3%,p = 0.002)。从普通急诊室转来的病人并没有因为 CPG 而发生变化(水平移动 2.2%,p = 0.17)。CPG发布后,儿科急诊室的心电图检查增加了13.7%(p = 0.005),但普通急诊室的心电图检查没有变化(水平移动-0.2%,p = 0.82):结论:在人口层面和急诊室,BRUEs 仍是儿科常见问题。尽管到普通急诊室就诊的婴儿人数不成比例,但儿科急诊室和普通急诊室对 CPG 建议的接受程度不同。这些发现可能有助于提高质量,改善对这些婴儿的护理,减少不必要的入院或转院。
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引用次数: 0
Using natural language processing in emergency medicine health service research: A systematic review and meta-analysis. 在急诊医学健康服务研究中使用自然语言处理:系统回顾和荟萃分析。
IF 3.4 3区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-05-16 DOI: 10.1111/acem.14937
Hao Wang, Naomi Alanis, Laura Haygood, Thomas K Swoboda, Nathan Hoot, Daniel Phillips, Heidi Knowles, Sara Ann Stinson, Prachi Mehta, Usha Sambamoorthi

Objectives: Natural language processing (NLP) represents one of the adjunct technologies within artificial intelligence and machine learning, creating structure out of unstructured data. This study aims to assess the performance of employing NLP to identify and categorize unstructured data within the emergency medicine (EM) setting.

Methods: We systematically searched publications related to EM research and NLP across databases including MEDLINE, Embase, Scopus, CENTRAL, and ProQuest Dissertations & Theses Global. Independent reviewers screened, reviewed, and evaluated article quality and bias. NLP usage was categorized into syndromic surveillance, radiologic interpretation, and identification of specific diseases/events/syndromes, with respective sensitivity analysis reported. Performance metrics for NLP usage were calculated and the overall area under the summary of receiver operating characteristic curve (SROC) was determined.

Results: A total of 27 studies underwent meta-analysis. Findings indicated an overall mean sensitivity (recall) of 82%-87%, specificity of 95%, with the area under the SROC at 0.96 (95% CI 0.94-0.98). Optimal performance using NLP was observed in radiologic interpretation, demonstrating an overall mean sensitivity of 93% and specificity of 96%.

Conclusions: Our analysis revealed a generally favorable performance accuracy in using NLP within EM research, particularly in the realm of radiologic interpretation. Consequently, we advocate for the adoption of NLP-based research to augment EM health care management.

目的:自然语言处理(NLP)是人工智能和机器学习的辅助技术之一,可从非结构化数据中创建结构。本研究旨在评估在急诊医学(EM)环境中使用 NLP 识别和分类非结构化数据的性能:我们在MEDLINE、Embase、Scopus、CENTRAL和ProQuest Dissertations & Theses Global等数据库中系统地搜索了与急诊医学研究和NLP相关的出版物。独立审稿人对文章质量和偏差进行了筛选、审查和评估。NLP 的使用分为综合征监测、放射学解释和特定疾病/事件/综合征的识别,并报告了各自的敏感性分析。计算了NLP使用的性能指标,并确定了接收者操作特征曲线汇总(SROC)下的总体面积:共有 27 项研究进行了荟萃分析。研究结果表明,总体平均灵敏度(召回率)为 82%-87%,特异性为 95%,SROC 下面积为 0.96 (95% CI 0.94-0.98)。在放射学判读中,NLP的表现最佳,总体平均灵敏度为93%,特异性为96%:我们的分析表明,在电磁学研究中使用 NLP 的准确性普遍较高,尤其是在放射学判读领域。因此,我们提倡采用基于 NLP 的研究来加强电磁医疗管理。
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引用次数: 0
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Academic Emergency Medicine
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