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Washington and Alaska statewide fetal alcohol spectrum disorder diagnostic clinical networks: Comparison of three decades of 4-Digit Code diagnostic outcomes and prenatal alcohol exposure histories. 华盛顿州和阿拉斯加州胎儿酒精谱系障碍诊断临床网络:三十年来 4 位数代码诊断结果与产前酒精接触史的比较。
Pub Date : 2023-01-01 Epub Date: 2023-12-29
Susan J Astley Hemingway, Michael Baldwin, Pierce-Bulger Marilyn

Background: Fetal alcohol spectrum disorder (FASD) screening, diagnosis, intervention, research and prevention hinges on establishment of interdisciplinary FASD diagnostic clinics using an evidence-based method of diagnosis. In 1993 Washington State opened the first interdisciplinary FASD diagnostic clinic sponsored by the CDC as a FASD primary prevention study. Clinic data was used to develop the evidence-based FASD 4-Digit Diagnostic Code, paving the way for the clinic's expansion into a statewide network of FASD diagnostic clinics (Washington Fetal Alcohol Syndrome Diagnostic & Prevention Network), now in its 30th year. Alaska adopted this Washington model in 1999. Both states have also participated in the CDC Pregnancy Risk Assessment Monitoring System and Behavioral Risk Factor Surveillance System since the 1990s. Study objectives were to describe the two statewide FASD diagnostic networks; graphically compare the 4-Digit-Code FASD diagnoses and prenatal alcohol exposure (PAE) over 2-3 decades and illustrate how network data helped guide FASD public health policies and track successful prevention efforts.

Methods: Retrospective descriptive study.

Results: FASD diagnostic outcomes were similar across 2,532 Washington and 2,469 Alaskan patients. PAE in each State followed similar annual trajectories from 1991-2020. Both States documented significant decreases in FAS and PAE in the 1990s. Clinic data helped guide public health policies.

Conclusions: Both States demonstrated the feasibility and value of establishing statewide interdisciplinary FASD diagnostic clinical networks using the FASD 4-Digit-Code. Legislative support, centralized data collection, and use of a single, evidence-based FASD diagnostic system have been key to the long-term, ongoing success of these two diagnostic networks.

背景:胎儿酒精中毒谱系障碍(FASD)的筛查、诊断、干预、研究和预防取决于采用循证诊断方法建立跨学科的 FASD 诊断诊所。1993 年,华盛顿州开设了第一家由疾病预防控制中心赞助的跨学科 FASD 诊断诊所,作为 FASD 初级预防研究。诊所的数据被用于制定以证据为基础的 FASD 4 位诊断代码,为诊所扩展为全州范围的 FASD 诊断诊所网络(华盛顿州胎儿酒精综合症诊断和预防网络)铺平了道路,如今该网络已走过了 30 个年头。阿拉斯加州于 1999 年采用了华盛顿州的这一模式。自 20 世纪 90 年代以来,这两个州都参与了美国疾病预防控制中心的妊娠风险评估监测系统和行为风险因素监测系统。研究目的是描述这两个全州范围的 FASD 诊断网络;以图表的形式比较二三十年来的 4 位数代码 FASD 诊断和产前酒精暴露 (PAE),并说明网络数据如何帮助指导 FASD 公共卫生政策和跟踪成功的预防工作:方法:回顾性描述研究:结果:2532 名华盛顿州和 2469 名阿拉斯加州患者的 FASD 诊断结果相似。从 1991 年到 2020 年,每个州的 PAE 都遵循相似的年度轨迹。这两个州都记录了 20 世纪 90 年代 FAS 和 PAE 的显著下降。诊所数据有助于指导公共卫生政策:这两个州都证明了利用 FASD 4 位数代码建立全州跨学科 FASD 诊断临床网络的可行性和价值。立法支持、集中数据收集以及使用单一的、以证据为基础的 FASD 诊断系统是这两个诊断网络取得长期、持续成功的关键。
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引用次数: 0
Neonatal Restraint Condition: The Executives and Current Ideas 新生儿约束条件:执行者和当前观点
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.16
H. Akinbi
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引用次数: 0
Psychosocial Well-Being during the COVID-19 Pandemic COVID-19大流行期间的社会心理健康
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.19
H. Akinbi
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引用次数: 0
Advances in Pediatric Research Overview 儿科研究进展综述
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.8
G. Ross
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引用次数: 0
Hereditary Syndromes Associated with Intellectual Disability 与智力残疾相关的遗传综合征
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.15
H. Akinbi
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引用次数: 0
Oxygen Therapy in Preterm Infants: Recommendations for Practice 早产儿氧疗:实践建议
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.18
H. Akinbi
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引用次数: 0
Streamlining Nutrition of Preterm and Term Infants 精简早产儿和足月儿的营养
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.17
H. Akinbi
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引用次数: 0
Challenges, Risk and Approaches of SARS-CoV-2 and COVID-19 in Children SARS-CoV-2和COVID-19在儿童中的挑战、风险和对策
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.56
S. Bittmann, G. Ross
Advances in Pediatric Research publish original research articles with a potential impact on the fields of neonatology, pediatrics, and adolescent medicine. The editors seek forward-looking, cutting-edge original research, case studies, and systematic reviews. We will also publish invited editorials, expert viewpoints and counterpoints. Advances in Pediatric Research are primarily a clinical research journal; yet translational, genetic and compelling basic science research articles are welcome.
《儿科研究进展》发表的原创研究文章对新生儿科、儿科和青少年医学领域具有潜在影响。编辑们寻求前瞻性的、前沿的原创研究、案例研究和系统评论。我们还将发表特邀社论、专家观点和对应物。《儿科研究进展》主要是一本临床研究杂志;然而,翻译、遗传和引人注目的基础科学研究文章是受欢迎的。
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引用次数: 0
Preventive treatment adherence and challenges in its effectiveimplementation among HIV exposed children in the public hospitals inIlubabor zone: Retrospective follow-up study ilubabor地区公立医院HIV暴露儿童预防治疗依从性及其有效实施的挑战:回顾性随访研究
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.36
Dessalegn Nigatu
Introduction: Despite World health organization universal recommendation of Preventive Therapy, only 56% of pediatrics on ART receiving this intervention. The aim of this study was to determine the magnitude of Preventive Therapy and challenges in its effective implementation among HIV exposed children in Ilu Ababor zone public hospitals. Materials: A facility based retrospective cohort study was used among 300 children’s’ reviewing records by standard structured questionnaires and interviewing their primary caregivers. Data were cleared and entered into Epi-info version 3.1 and exported into SPSS version 24 for further analysis and a binary logistic regression was used to investigate factors associated with uptake of Preventive Therapy. Variables with p-value <0.2 in bivariable analysis were entered into the multivariable analysis. Odds ratio with 95% confidence interval was estimated to show the strength of association and the p-value <0.05 was used to declare as statistical significance in the multivariable analysis. Results: Out of 300 (293) records were reviewed with a response rate of 97.6%. Almost all of the respondents were female 279 (93%) also about half (48%) of the respondents were orthodox in religion and a few (3.4%) of them have had primary education. More than half the exposed infants’ age was b/n 13-18 months. Moreover, about 65.5% of guardians were well awared about preventive treatment. The strongest independent predictors of poor adherence to Preventive Therapy are not able to read [OR=0.153 (0.027-0.863) P< 0.330], long procedure in getting the drug (OR=9.913[2.825, 34.731], p=<0.000), Shortage of drug availability [OR=9.91 (2.829-34.73), P< 0.000], missed dose greater than three doses [OR=2.69 (1.17-6.26), p=<0.022], Persistent diarrhoea [OR=4.324 (1.067-17.530), p=0.040] were associated with Preventive Therapy among HIV exposed children. Conclusion: Preventive Therapy in study area was found to be relatively high and long procedure, shortage of preventive drug and persistent diarrhea were found to be significant predictors of Preventive Therapy, Hence, to avert this, accessing drugs, treating persistent diarrhea and decreasing waiting time were plays unfold role to increases uptake of Preventive Therapy.
尽管世界卫生组织普遍推荐预防性治疗,但只有56%的接受抗逆转录病毒治疗的儿科接受这种干预。本研究的目的是确定预防性治疗的规模及其在伊卢阿伯特地区公立医院艾滋病毒暴露儿童中有效实施的挑战。资料:采用标准的结构化问卷和对主要照顾者的访谈,对300名儿童进行回顾性队列研究。清除数据并输入Epi-info 3.1版本,导出到SPSS 24版本进行进一步分析,并使用二元逻辑回归来调查与预防性治疗摄取相关的因素。将双变量分析中p值<0.2的变量纳入多变量分析。以95%置信区间的比值比表示关联强度,以p值<0.05表示多变量分析具有统计学显著性。结果:共查阅病历300份(293份),回复率为97.6%。几乎所有的受访者都是女性,279人(93%),约一半(48%)的受访者信仰正统宗教,其中少数(3.4%)接受过小学教育。超过一半的暴露婴儿的年龄在13-18个月之间。此外,约65.5%的监护人了解预防治疗。预防治疗依从性差的最强独立预测因子是无法阅读[OR=0.153 (0.027-0.863) P< 0.330]、获得药物的程序长(OR=9.913[2.825, 34.731], P =<0.000]、药物供应短缺[OR=9.91 (2.829-34.73), P< 0.000]、错过剂量大于3剂[OR=2.69 (1.17-6.26), P =<0.022]、持续性腹泻[OR=4.324 (1.067-17.530), P =0.040]与HIV暴露儿童预防治疗相关。结论:研究区预防治疗费用较高且疗程较长,预防药物短缺和持续性腹泻是预防治疗的重要预测因素,为避免这种情况,获取药物、治疗持续性腹泻和减少等待时间对提高预防治疗的接受度起着重要作用。
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引用次数: 0
Low Birth Weight and Its Associated Factors among Neonates Born in the Public Health Institutions of Nekemte Town, East Wallaga Zone, West Oromia, Ethiopia 埃塞俄比亚西奥罗米亚东瓦拉加区Nekemte镇公共卫生机构出生的新生儿低出生体重及其相关因素
Pub Date : 2021-01-01 DOI: 10.35248/2385-4529.21.8.39
Tariku Gidada
Background: Birth weight is an important indicator to judge the survival chances of the new-born. Many of the new-born die during their first year of life because of low birth weight as they become the victims of protein energy malnutrition and infection. Low birth weight has intergeneration effect in Ethiopia. However, no other study has been conducted on status of birth weight in the study area. Hence, the need to conduct this study was to provide current information about the birth weight and associated factors among neonates born in public health institutions in Nekemte town, East Wollega zone, Oromia, west Ethiopia. Objective: To assess neonatal birth weight and its associated factors among births at public health institutions providing delivery service in Nekemte town. Method: A community based cross-sectional study was conducted among 340 mothers who gave birth in Nekemte town in the public health institutions from September 10/2014 to December 10/2014. Simple random sampling was used to identify study unit. Data were collected using a pretested and structured questionnaire by a face-to-face interview technique and the neonate was weighted recorded. Logistic regression analyses method was used to check associations and control confounding. Result: 62(18.2%) neonates born with low birth weight. Hypertension [AOR =1.64;95% ,CI=(1.543, 2.39)], gestational age less than 37 weeks[AOR =12.08, 95% CI=(1.020 , 2.354)], family size [AOR= 5.719, 95%,CI= (1.660,3.703)], birth spacing duration [AOR=4.1828,95% CI=(1.086, 3.389)], HIV/AIDS [(AOR= 4.072,95%CI=1.842, 2.005], source of drinking water[AOR 2.485;95%, CI=1.053, 5.865)], were some of the major risk factors revealed to affect birth weight. Conclusion: The prevalence of low birth weight was high in the study area. The finding of this study revealed that: birth spacing, HIV/AIDS, source of drinking water, family size, and hypertension during pregnancy were significantly associated with birth weight. Thus, since the low birth weight has intergenerational effect, an organized effort should be made at all levels to improve the birth weight of neonates.Keywords: Pingchan granule; Motor function; Non-motor function; Sleep; Autonomic function; Psychological disorders; Quality of life.
背景:出生体重是判断新生儿存活率的重要指标。许多新生儿在出生后一年内死亡,因为他们成为蛋白质能量营养不良和感染的受害者,出生体重过低。在埃塞俄比亚,低出生体重具有代际效应。然而,在研究地区还没有其他关于出生体重状况的研究。因此,开展这项研究的必要性是提供有关在埃塞俄比亚西部奥罗米亚州东沃勒加区Nekemte镇公共卫生机构出生的新生儿出生体重和相关因素的最新信息。目的:了解Nekemte镇提供接生服务的公共卫生机构新生儿出生体重及其相关因素。方法:对2014年9月10日至2014年12月10日在Nekemte镇公共卫生机构分娩的340名产妇进行基于社区的横断面研究。采用简单随机抽样确定研究单位。数据收集采用预先测试和结构化问卷,面对面访谈技术和新生儿加权记录。采用Logistic回归分析方法检查相关性和控制混杂。结果:低出生体重儿62例(18.2%)。高血压[AOR= 1.64;95%,CI=(1.543, 2.39)]、胎龄小于37周[AOR= 12.08, 95%CI=(1.020, 2.354)]、家庭规模[AOR= 5.719, 95%CI=(1.660,3.703)]、生育间隔时间[AOR=4.1828,95% CI=(1.086, 3.389)]、HIV/AIDS [AOR= 4.072,95%CI=1.842, 2.005]、饮用水来源[AOR= 2.485,95%CI= 1.053, 5.865)]是影响出生体重的主要危险因素。结论:研究区低出生体质量发生率较高。研究结果表明:生育间隔、艾滋病、饮用水来源、家庭规模和孕期高血压与出生体重显著相关。因此,由于低出生体重具有代际效应,应在各级有组织地努力改善新生儿的出生体重。关键词:平禅颗粒;运动机能;非功能;睡眠;自主功能;心理障碍;生活质量。
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Advances in pediatric research
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