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Predictive Value of the CHA2DS2-VASc Score on Exercise Capacity in Patients with Cardiovascular Disease. CHA2DS2-VASc评分对心血管疾病患者运动能力的预测价值
0 REHABILITATION Pub Date : 2025-10-31 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251381134
Eijiro Yagi, Koichiro Matsumura, Shohei Hakozaki, Yuki Uchigashima, Jun Shiroyama, Mitsuki Hase, Tomoya Nanba, Masafumi Ueno, Gaku Nakazawa

Background: Cardiac rehabilitation (CR) improves exercise capacity and is strongly recommended in clinical guidelines. However, no established scoring system exists to predict improvements in exercise capacity following CR.

Objective: This study aimed to assess whether the CHA2DS2-VASc score could serve as a predictive scoring system for improvements in exercise capacity after CR.

Methods: Of the 99 patients with cardiovascular disease who participated in the hospital-based CR, those who were ineligible were excluded. The remaining patients were stratified into 2 groups based on the median CHA2DS2-VASc score. Changes in peak oxygen uptake (peak VO2) and clinical parameters from baseline to follow-up were compared between the groups.

Results: A total of 46 patients (median age, 74 years; 72% male) were stratified according to the median CHA2DS2-VASc score of 4. Patients in the high-score group (CHA2DS2-VASc score ⩾ 4) were older, more likely to be female, and had elevated B-type natriuretic peptide levels compared with those in the low-score group (CHA2DS2-VASc score <4). The prevalence of comorbidities was similar between the groups. The low-score group showed a significantly greater improvement in peak VO2 from baseline to follow-up compared with that of the high-score group (2.8 [1.3-4.7] vs 0.4 [-1.0 to 2.4] mL/kg/min, P < 0.01). Spearman's rank correlation analysis showed a significant negative correlation between CHA2DS2-VASc scores and the change in peak VO2 between baseline and follow-up (r = -0.37, P = .01). A CHA2DS2-VASc score <4 was independently associated with an increase in peak VO2 (β = 0.50, 95% confidence interval 0.23-2.14, P = .01) in the multivariate analysis using multiple linear regression.

Conclusions: The CHA2DS2-VASc score may be a useful tool for predicting potential improvements in exercise capacity after CR.

背景:心脏康复(CR)可以提高运动能力,在临床指南中被强烈推荐。目的:本研究旨在评估CHA2DS2-VASc评分是否可以作为CR后运动能力改善的预测评分系统。方法:在99例参加医院CR的心血管疾病患者中,排除不符合条件的患者。其余患者根据CHA2DS2-VASc中位评分分为2组。比较各组从基线到随访期间的峰值摄氧量(峰值VO2)和临床参数的变化。结果:共有46例患者(中位年龄74岁,72%男性)按照CHA2DS2-VASc中位评分4分进行分层。高分组(CHA2DS2-VASc评分大于或等于4)的患者年龄较大,更有可能是女性,并且与低分组的患者相比,b型利钠肽水平升高(与高分组相比,从基线到随访的CHA2DS2-VASc评分为2)(2.8 [1.3-4.7]vs 0.4[-1.0至2.4]mL/kg/min, P 2DS2-VASc评分和基线和随访之间峰值VO2的变化(r = -0.37, P = 0.01)。A CHA2DS2-VASc评分2 (β = 0.50, 95%置信区间0.23-2.14,P =。01)在多变量分析中采用多元线性回归。结论:CHA2DS2-VASc评分可能是预测CR后运动能力潜在改善的有用工具。
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引用次数: 0
Impact of Physical Growth and Development on Paediatric Lower-Limb Prosthetic Provision: Prosthetist Perspectives and Clinical Casefile Analysis From Cambodia. 身体生长发育对儿科下肢假肢提供的影响:柬埔寨假肢专家的观点和临床病例分析。
0 REHABILITATION Pub Date : 2025-10-27 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251384354
Claudia Ghidini, Caitlin E Edgar, Carson Harte, Sisary Kheng, Anthony M J Bull

Introduction: Growth affects prosthetic provision in children, leading to socket fit issues and prosthetic length discrepancy. Despite increasing numbers of paediatric amputations, no studies have systematically analysed clinical casefiles or interviewed prosthetists to identify growth-related challenges and mitigation strategies, particularly in low-resource environments where polypropylene (PP) technology is used. This study addresses this gap by interviewing prosthetists and analysing clinical casefiles.

Methods: This study combined qualitative interviews with Cambodian prosthetists and analysis of 62 clinical casefiles. Casefile analysis documented growth-related issues, adjustment methods, and time between interventions. Thematic analysis was applied to interviews.

Results: Five themes were identified, highlighting that: sockets and their use can account for growth through careful oversizing and using liners/socks; handcrafted adjustments that rely on thermoplastic technology can also accommodate for growth; lack of adjustment increases waste and clinical attendance; poor socket fit causes pain and residual limb problems; and growth issues result in universal problems of socket fit issues and prosthetic length discrepancy.

Discussion: This study is the first to interview paediatric prosthetists to assess growth-related challenges, identify mitigation strategies, and combine these qualitative findings with hard clinical evidence. PP prosthetic systems offer cost-effectiveness and increased adjustability compared to modular components and carbon fibre sockets. However, this adjustability is still limited, leading to waste of resources and increased clinical time. Finally, longer-than-recommended replacement timelines are concerning, and more research is necessary to understand these longer delays. Addressing these limitations is crucial, particularly in low-resource environments, to improve accessibility and prevent secondary impairments.

导言:生长影响儿童假体的提供,导致牙槽吻合问题和假体长度差异。尽管儿科截肢数量不断增加,但没有研究系统地分析临床病例档案或采访假肢专家,以确定与生长相关的挑战和缓解策略,特别是在使用聚丙烯(PP)技术的资源匮乏环境中。本研究通过采访义肢专家和分析临床病例档案来解决这一差距。方法:本研究结合对柬埔寨义肢医师的定性访谈和对62例临床病例的分析。病例分析记录了与生长有关的问题、调整方法和干预之间的时间。专题分析应用于访谈。结果:确定了五个主题,突出表明:插座及其使用可以通过谨慎的超大尺寸和使用衬垫/袜子来解释增长;依靠热塑性塑料技术的手工调整也可以适应增长;缺乏调整会增加浪费和就诊人数;不合适的窝位会导致疼痛和残肢问题;生长问题导致了普遍存在的问题比如关节窝吻合问题和假体长度不一致。讨论:本研究首次采访了儿科义肢专家,以评估与生长相关的挑战,确定缓解策略,并将这些定性发现与确凿的临床证据结合起来。与模块化组件和碳纤维插座相比,PP假肢系统具有成本效益和更高的可调节性。然而,这种可调节性仍然有限,导致资源的浪费和临床时间的增加。最后,超过建议的更换时间表令人担忧,需要更多的研究来了解这些较长的延迟。解决这些限制对于改善可及性和预防继发性损伤至关重要,特别是在资源匮乏的环境中。
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引用次数: 0
Community Support for Caregivers of Children With Sickle Cell Disease: A 3-Year Process Evaluation. 镰状细胞病儿童护理人员的社区支持:3年过程评价
0 REHABILITATION Pub Date : 2025-10-23 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251387234
Sophia C Larson, Hunter G Moore, Rosemary Britts, Alison S Towerman, Ashley J Housten, Madison Griffith, Kaylin A Antonoff, Kelly M Harris, Allison A King, Catherine R Hoyt

Background: Sickle cell disease (SCD), the most common monogenetic childhood disorder, imposes a significant psychosocial and financial burden on caregivers of affected children. Despite the availability of community-based support programs, few are tailored to the specific identified needs of caregivers managing SCD. This study presents a comprehensive program evaluation of a community-partnered caregiver retreat hosted by the St. Louis Sickle Cell Association (SCA).

Methods: Researchers collaborated with the SCA to evaluate their annual weekend-long retreat. Year 1 employed a cross-sectional design using the General Self-Efficacy Scale. Year 2 implemented a pre-post design using the Family Empowerment Scale. In Year 3, a mixed-methods design included the Social Support Survey Instrument, 2 focus groups, and 6 interviews. Data were analyzed using descriptive and inferential statistics and thematic analysis.

Results: Findings revealed no significant group-level empowerment changes in Year 2, though individual improvements were noted. In Year 3, caregivers reported strong emotional and social support but low tangible support. Thematic analysis identified 5 themes: SCD awareness gaps, caregiving burden, psychological toll, support variability, and caregiver-identified solutions. Caregivers emphasized a need for peer connection, mental health support, practical advocacy training, and expanded access to retreat programming.

Discussion: This program evaluation demonstrates the meaningful support provided by community-based caregiver retreats while highlighting areas for enhancement. The findings underscore the value of systematic evaluation in identifying program strengths and opportunities for improvement to better serve caregiver needs.

Conclusion: Community-based partnerships can enhance support for caregivers of children with SCD. This evaluation identifies essential program components and demonstrates how systematic assessment can inform program development to better address unmet caregiver needs and advance health equity.

背景:镰状细胞病(SCD)是最常见的单基因儿童疾病,给患病儿童的照料者带来了重大的社会心理和经济负担。尽管有基于社区的支持项目,但很少有针对护理人员管理SCD的特定需求的。本研究提出了由圣路易斯镰状细胞协会(SCA)主办的社区合作护理人员静修的综合项目评估。方法:研究人员与SCA合作评估他们每年的周末长撤退。第一年采用一般自我效能量表的横断面设计。二年级采用家庭赋权量表实施岗前设计。在三年级,采用混合方法设计,包括社会支持调查工具、2个焦点小组和6个访谈。数据分析采用描述性和推断性统计和专题分析。结果:调查结果显示,在第2年,虽然个人的进步被注意到,但没有显著的群体层面的授权变化。在第三年级,护理人员报告了强烈的情感和社会支持,但缺乏有形支持。专题分析确定了5个主题:可持续发展意识差距、照护负担、心理损失、支持可变性和照护者确定的解决方案。护理人员强调需要同伴联系、心理健康支持、实际宣传培训和扩大获得静修计划的机会。讨论:该项目评估展示了社区护理人员静修所提供的有意义的支持,同时突出了需要改进的领域。研究结果强调了系统评估在确定项目优势和改进机会以更好地满足护理人员需求方面的价值。结论:基于社区的合作伙伴关系可以增强对SCD儿童照料者的支持。该评估确定了规划的基本组成部分,并展示了系统评估如何为规划制定提供信息,以更好地解决未满足的护理人员需求并促进卫生公平。
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引用次数: 0
Behaviour Change Considerations to Promote Physical Activity Participation among Individuals with Quiescent Inflammatory Bowel Disease: Barriers and Facilitators. 行为改变考虑促进静止性炎症性肠病患者参与体育活动:障碍和促进因素
0 REHABILITATION Pub Date : 2025-10-20 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251382074
Banke Oketola, Sandra Webber, Harminder Singh, Maia Kredentser, Kristin Reynolds, Gayle Restall

Background: Most individuals with inflammatory bowel diseases (IBD) do not engage in optimum levels of physical activity (PA). This study aimed to identify important factors to consider when promoting PA participation among individuals with quiescent or mildly active IBD.

Methods: In this qualitative description study, we purposively enrolled 15 Manitobans with quiescent IBD. Data was collected via semi-structured interviews conducted on Zoom. Using the Capability, Opportunity, Motivation, and Behaviour (COM-B) model, we elicited factors that influence PA behaviour. We performed thematic analysis of transcribed interviews using NVivo.

Results: Participants' (N = 15) ages ranged between 20 and 37 years, majority were female (n = 8), and most had a diagnosis of ulcerative colitis (UC) (n = 10). None was a current smoker. Thematic analysis identified persistent symptoms, PA engagement prior to IBD diagnosis, PA routine, coping strategies and determination as themes that influenced 'capability' for PA participation. Social support, type of employment, bathroom access, and finances influenced 'opportunity'. Awareness of the benefits of PA on IBD, relevant knowledge, social support, and personal goals promoted 'motivation' for PA participation. Sex differences were noted in participants' perspectives related to safety concerns and the social context of workout spaces.

Conclusion: Using the COM-B model, we elicited barriers (including IBD-related persistent symptoms, lack of knowledge of PA) and facilitators (social support, coping strategies, ability to track PA progress) that influence PA behaviour among adults with quiescent IBD. These factors are important considerations when promoting PA participation among individuals with IBD.

背景:大多数炎症性肠病(IBD)患者不从事最佳水平的身体活动(PA)。本研究旨在确定在促进静止或轻度活动性IBD患者参与PA时需要考虑的重要因素。方法:在这项定性描述研究中,我们有目的地招募了15名患有静止性IBD的马尼托巴人。数据是通过在Zoom上进行的半结构化访谈收集的。利用能力、机会、动机和行为(COM-B)模型,我们得出了影响个人助理行为的因素。我们使用NVivo对转录的访谈进行了专题分析。结果:参与者(N = 15)年龄在20至37岁之间,大多数为女性(N = 8),大多数诊断为溃疡性结肠炎(UC) (N = 10)。没有人现在吸烟。主题分析确定了持续症状、IBD诊断前的PA参与、PA常规、应对策略和决心是影响PA参与“能力”的主题。社会支持、就业类型、卫生间使用和经济状况影响“机会”。认识到PA对IBD的益处、相关知识、社会支持和个人目标促进了PA参与的“动机”。参与者对安全问题和健身场所的社会背景的看法也存在性别差异。结论:使用COM-B模型,我们得出了影响静止性IBD成人患者PA行为的障碍(包括IBD相关的持续症状、缺乏对PA的知识)和促进因素(社会支持、应对策略、跟踪PA进展的能力)。在促进IBD患者参与PA时,这些因素是重要的考虑因素。
{"title":"Behaviour Change Considerations to Promote Physical Activity Participation among Individuals with Quiescent Inflammatory Bowel Disease: Barriers and Facilitators.","authors":"Banke Oketola, Sandra Webber, Harminder Singh, Maia Kredentser, Kristin Reynolds, Gayle Restall","doi":"10.1177/27536351251382074","DOIUrl":"10.1177/27536351251382074","url":null,"abstract":"<p><strong>Background: </strong>Most individuals with inflammatory bowel diseases (IBD) do not engage in optimum levels of physical activity (PA). This study aimed to identify important factors to consider when promoting PA participation among individuals with quiescent or mildly active IBD.</p><p><strong>Methods: </strong>In this qualitative description study, we purposively enrolled 15 Manitobans with quiescent IBD. Data was collected via semi-structured interviews conducted on Zoom. Using the Capability, Opportunity, Motivation, and Behaviour (COM-B) model, we elicited factors that influence PA behaviour. We performed thematic analysis of transcribed interviews using NVivo.</p><p><strong>Results: </strong>Participants' (N = 15) ages ranged between 20 and 37 years, majority were female (n = 8), and most had a diagnosis of ulcerative colitis (UC) (n = 10). None was a current smoker. Thematic analysis identified persistent symptoms, PA engagement prior to IBD diagnosis, PA routine, coping strategies and determination as themes that influenced 'capability' for PA participation. Social support, type of employment, bathroom access, and finances influenced 'opportunity'. Awareness of the benefits of PA on IBD, relevant knowledge, social support, and personal goals promoted 'motivation' for PA participation. Sex differences were noted in participants' perspectives related to safety concerns and the social context of workout spaces.</p><p><strong>Conclusion: </strong>Using the COM-B model, we elicited barriers (including IBD-related persistent symptoms, lack of knowledge of PA) and facilitators (social support, coping strategies, ability to track PA progress) that influence PA behaviour among adults with quiescent IBD. These factors are important considerations when promoting PA participation among individuals with IBD.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"14 ","pages":"27536351251382074"},"PeriodicalIF":0.0,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12550254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Telemedicine Challenges in Latin-America: Outcomes from Telerehabilitation Services During the COVID-19 Pandemic in Cali, Colombia-A Retrospective Cohort Study. 拉丁美洲的远程医疗挑战:哥伦比亚卡利市2019冠状病毒病大流行期间远程康复服务的结果——一项回顾性队列研究
0 REHABILITATION Pub Date : 2025-10-01 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251375637
Sara Gabriela Pacichana-Quinayaz, Lina María Rodríguez Vélez, Daniel Sánchez Cano, Olga Marina Hernández Orobio, María Ana Tovar Sánchez, Gloria Isabel Toro Córdoba, Francisco Javier Bonilla-Escobar

Purpose: The COVID-19 pandemic disrupted in-person healthcare and accelerated the adoption of telemedicine, for which most low- and middle-income countries were unprepared. This study describes the population, service delivery, and therapeutic outcomes of telerehabilitation in Cali, Colombia, during the pandemic, and identifies factors influencing its feasibility to guide future implementation in similar low-resource settings.

Methods: We conducted a retrospective cohort study using medical records from 2 rehabilitation centers in Cali, Colombia, including patients who received synchronous telerehabilitation between January 2020 and December 2021. Data on demographics, diagnoses (grouped as mental health, neurological, chronic, post-traumatic, or unspecified), and outcomes (recovery, dropout, continued care) were collected using a structured form and analyzed with descriptive statistics and non-parametric tests (Wilcoxon, Kruskal-Wallis, chi-square, or Fisher's exact), with significance set at p < .05.

Results: We analyzed 1572 patients receiving telerehabilitation. Most were women (65.4%), aged 36 to 64 (46.5%), with trauma sequelae (32.8%) and mental health conditions (26.3%) as common diagnoses. Main services were physiatry (32%), psychosocial therapy (29%), and physiotherapy (27%). Most sessions were by phone (67.5%) and completed successfully (90%). Recovery was reported in 6.4% of cases; 13.3% completed treatment, 72.3% required ongoing care, and 3% dropped out. Completion was more common in older patients (p < .05).

Conclusions: The COVID-19 pandemic underscored telerehabilitation's vital role in Latin America, revealing access gaps and the need for further research to address socioeconomic, educational, and digital barriers affecting vulnerable populations. The patterns of telerehabilitation utilization varied notably by age, sex, and diagnosis, highlighting the necessity of strengthening and adapting these services to improve health outcomes and ensure equitable access. Gaps remain in areas of telerehabilitation such as, mental health, cardiovascular diseases and ophthalmology, underscoring the need for broader implementation and integration across specialties.

目的:2019冠状病毒病大流行扰乱了面对面的医疗保健,加速了远程医疗的采用,而大多数低收入和中等收入国家对此毫无准备。本研究描述了大流行期间哥伦比亚卡利远程康复的人口、服务提供和治疗结果,并确定了影响其可行性的因素,以指导今后在类似的低资源环境中实施远程康复。方法:我们使用哥伦比亚卡利2个康复中心的医疗记录进行了一项回顾性队列研究,包括2020年1月至2021年12月期间接受同步远程康复的患者。统计数据、诊断(分为精神健康、神经系统、慢性、创伤后或未明确)和结果(康复、辍学、继续治疗)采用结构化形式收集,并使用描述性统计和非参数检验(Wilcoxon、Kruskal-Wallis、卡方或Fisher精确)进行分析,显著性设置为p。大多数是女性(65.4%),年龄在36至64岁之间(46.5%),常见的诊断是创伤后遗症(32.8%)和精神健康状况(26.3%)。主要服务项目为物理治疗(32%)、社会心理治疗(29%)和物理治疗(27%)。大多数会议是通过电话(67.5%)和成功完成(90%)。6.4%的病例报告康复;13.3%完成了治疗,72.3%需要持续治疗,3%退出治疗。结论:2019冠状病毒病大流行凸显了远程康复在拉丁美洲的重要作用,揭示了获取差距,需要进一步研究,以解决影响弱势群体的社会经济、教育和数字障碍。远程康复利用的模式因年龄、性别和诊断而明显不同,突出表明有必要加强和调整这些服务,以改善健康结果并确保公平获得。在心理健康、心血管疾病和眼科等远程康复领域仍然存在差距,这突出表明需要更广泛地实施和跨专业整合。
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引用次数: 0
Injury Risk Factors of the Tennis Serve: A Systematic Review and Meta-Analysis. 网球发球损伤的危险因素:系统回顾与meta分析。
0 REHABILITATION Pub Date : 2025-10-01 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251374616
John Bradley, Ben L Langdown, David Bowmaker, Stewart Kerr

Background: A key stroke in tennis is the serve. It is the most strenuous stroke in the game and has the greatest potential for injury. The serve has been broken down into a number of key stages to allow analysis of the movements involved.

Objective: The aim of this study was to conduct a systematic review of all injuries related to the stages of the tennis serve and to assess their relative impact on the risk of injury using a meta-analysis.

Methods: A systematic search was conducted across 8 electronic databases, supplemented with searches of grey literature. Eligible studies presented data from injured (injury group) and uninjured (control group) tennis players in a form that allowed further analysis of each risk factor for comparison. All results were presented as effect sizes (Cohen's d) to allow comparison of each risk factor and to identify the most important risk factors associated with injury. Overall study quality was assessed using an adapted Downs and Blacks checklist.

Results: A total of 29 studies were included in the meta-analysis, identifying 130 risk factors. 36 risk factors had an effect size suggesting a large or significant association with injury in tennis players (d ⩾ 0.8 or ⩽-0.8). These were divided into general risk factors and those associated with the preparation, acceleration and follow-through phases of the tennis serve. Seven of the risk factors were from 3 or more studies allowing meta-analysis, 3 were from 2 studies and 26 were from a single study. Downs and Black checklist scores ranged from fair to good for the studies included in this review. There was no evidence of publication bias.

Conclusion: Meta-analysis identified dominant shoulder rotation strength, internal rotation range of movement, weekly tennis volume, age, body mass and height as risk factors for injury in the tennis serve.

背景:网球的一个关键击球是发球。这是比赛中最剧烈的一击,受伤的可能性也最大。发球被分解成几个关键的阶段,以便分析所涉及的动作。目的:本研究的目的是对所有与网球发球阶段相关的损伤进行系统回顾,并使用荟萃分析来评估它们对损伤风险的相对影响。方法:系统检索8个电子数据库,并辅以灰色文献检索。符合条件的研究将受伤(受伤组)和未受伤(对照组)网球运动员的数据以一种形式呈现,允许进一步分析每个风险因素进行比较。所有结果均以效应量(Cohen’s d)表示,以便对每个风险因素进行比较,并确定与损伤相关的最重要风险因素。总体研究质量采用唐斯和布莱克检查表进行评估。结果:荟萃分析共纳入29项研究,确定130个危险因素。36个风险因素的效应大小表明与网球运动员的损伤有很大或显著的关联(d大于或小于0.8或小于-0.8)。这些风险因素被分为一般风险因素和与网球发球的准备、加速和后续阶段相关的风险因素。7个风险因素来自3个或更多的研究,允许荟萃分析,3个来自2个研究,26个来自单一研究。Downs和Black检查表得分在本综述中纳入的研究中从一般到良好不等。没有证据表明存在发表偏倚。结论:荟萃分析发现优势肩旋力量、内旋运动范围、每周网球量、年龄、体重和身高是网球发球损伤的危险因素。
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引用次数: 0
Cryoneurolysis: A Novel Treatment for Management of Spasticity. Presentation of a Case Series. 冷冻神经溶解:一种治疗痉挛的新方法。案例系列报告。
0 REHABILITATION Pub Date : 2025-07-15 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251340216
Anton Pick, Rachel Dye, Melanie K Fleming

Background: Spasticity is a motor phenomenon occurring in disorders of the central nervous system that impacts on active and passive function, and quality of life. Pharmacological, physical and surgical management options are available, each of which have limitations. Cryoneurolysis is a technique developed for the treatment of pain which involves the controlled freezing and thawing of peripheral nerves. Recent case reports and series have suggested it may offer a novel treatment approach for pain associated with spasticity.

Objectives: To report on the evaluation of cryoneurolysis in the first cohort of patients treated in a UK spasticity clinic.

Methods: Eight patients with a variety of neurological conditions (aged 25-75 years) underwent cryoneurolysis. Each had been receiving regular botulinum toxin injections and had ongoing treatment goals. All patients first underwent diagnostic nerve blocks with local anaesthetic to determine their appropriateness for the treatment. Cryoneurolysis was then performed with ultrasound and nerve stimulator guidance. Assessments included goal attainment, Modified Ashworth Scale (MAS), ArmA, LegA and the patient reported impact of spasticity scale (PRISM), alongside patient satisfaction and side effect questionnaires. Assessments were at baseline and at regular intervals over 9 to 12 months.

Results: All patients attained at least one of their goals, with sustained effect for more than 6 months. MAS demonstrated mixed or modest improvements. Functional outcome measures (ArmA/LegA) showed several meaningful improvements, particularly in passive function. There was an indication of an improvement in PRISM across domains, which plateaued at 6 months. Post-procedure pain was the most common side effect but subsided in all affected patients by 3 months. Patient satisfaction was positive.

Conclusions: Our findings contribute to a growing base of case reports and series suggesting that cryoneurolysis could be a potentially useful treatment modality for spasticity. Future controlled studies should aim to evaluate cost-effectiveness and compare with existing treatments.

背景:痉挛是中枢神经系统疾病中发生的一种运动现象,影响主动、被动功能和生活质量。药理学,物理和外科治疗的选择是可用的,每一个都有局限性。冷冻神经溶解是一种治疗疼痛的技术,它涉及到周围神经的控制冻结和解冻。最近的病例报告和系列研究表明,它可能为痉挛相关疼痛提供一种新的治疗方法。目的:报道在英国痉挛诊所治疗的第一批患者中对冷冻神经溶解的评价。方法:8例不同神经系统疾病患者(年龄25-75岁)行冷冻神经松解术。每个人都接受了定期的肉毒杆菌注射,并有持续的治疗目标。所有患者首先接受诊断性神经阻滞和局部麻醉,以确定其治疗的适宜性。然后在超声和神经刺激器引导下进行冷冻神经溶解。评估包括目标实现、改良Ashworth量表(MAS)、ArmA、LegA和患者报告的痉挛影响量表(PRISM),以及患者满意度和副作用问卷。评估是在基线上进行的,并在9至12个月内定期进行。结果:所有患者均达到至少一个目标,且持续疗效超过6个月。MAS表现出混合或适度的改善。功能结果测量(ArmA/LegA)显示了一些有意义的改善,特别是在被动功能方面。有迹象表明,PRISM在各个领域都有所改善,在6个月时达到稳定水平。术后疼痛是最常见的副作用,但所有受影响的患者在3个月后消退。患者满意度为正。结论:我们的研究结果为越来越多的病例报告和系列报道提供了依据,表明冷冻神经溶解可能是治疗痉挛的一种潜在有效的治疗方式。未来的对照研究应旨在评估成本效益,并与现有治疗方法进行比较。
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引用次数: 0
Synergistic integration of epidural spinal cord stimulation with robotic therapy and neurorehabilitation to facilitate functional recovery in chronic sensorimotor complete spinal cord injury: A case series. 硬膜外脊髓刺激与机器人治疗和神经康复的协同整合促进慢性感觉运动完全性脊髓损伤的功能恢复:一个病例系列。
0 REHABILITATION Pub Date : 2025-06-24 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251343738
Seng Kwee Wee, Zhi Yan Ng Valerie, Min Wee Phua, Wen Li Lui, Fatimah Misbaah, Rui Xin Justin Ker, Wai Hoe Ng, Kai Rui Wan

Objective: To present the rehabilitation considerations in prehabilitation and the rehabilitation phase post spinal cord stimulator implantation; and to evaluate the efficacy of synergistic combination of epidural spinal cord stimulation (SCS) with motor imagery, trunk rehabilitation, robotic and overground gait training in improving mobility in persons with sensorimotor complete spinal cord injury (SCI).

Design: A non-controlled before-after clinical trial.

Methods: Epidural spinal cord stimulators were implanted into 3 participants with complete thoracic SCI (Thoracic 4, Thoracic 2 and Thoracic 10 respectively). They underwent 1 month of prehabilitation, followed by 7 months of daily rehabilitation post-implantation, consisting of SCS, motor imagery, trunk rehabilitation, robotic therapy and overground gait training. Pre-post assessments include the American Spinal Injury Association Impairment Scale (AIS) examination, Spinal Cord Independence Measure version III (Mobility subscale) (SCIM-III), Walking Index for Spinal Cord Injury II (WISCI-II), Trunk Assessment Scale for Spinal Cord Injury (TASS), Five Times Sit-to-Stand (5×STS) and 2-minute Walk Test (2mWT).

Results: Post rehabilitation, there were improvements in WISCI-II, TASS, 5×STS and 2mWT in all 3 participants; and no change in AIS sensory scores. Only participants 2 and 3 exhibited slight improvement in SCIM-III. The WISCI-II of all participants improved, ranging from 3 levels to 9 levels, which was considered a clinically meaningful change. Furthermore, the change in TASS exceeded the minimal clinically important difference (MCID) of 4 points for two participants. The change in 5×STS exceeded the MCID of 2.27 seconds for all participants. These significant improvements translated into the participants' ability to perform sit-to-stand independently and ambulate with a rollator frame under supervision of a carer.

Conclusion: This clinical trial demonstrated proof-of-concept and promising findings that support our rehabilitation protocol in improving functional mobility of people with sensorimotor complete SCI, which may be replicated in future studies.*The study protocol was registered with Clinical-trials.gov (NCT05644171; Registered 13 November 2022. https://clinicaltrials.gov/ct2/show/NCT05644171).

目的:探讨脊髓刺激器植入前及康复阶段的康复注意事项;评估硬膜外脊髓刺激(SCS)联合运动想象、躯干康复、机器人和地面步态训练对改善感觉-运动完全性脊髓损伤(SCI)患者活动能力的效果。设计:非对照的前后对照临床试验。方法:将硬膜外脊髓刺激器植入3例完全性胸椎脊髓损伤患者(分别为胸椎4、胸椎2和胸椎10)。他们接受了1个月的预康复,随后进行了7个月的植入后日常康复,包括SCS、运动想象、躯干康复、机器人治疗和地上步态训练。前后评估包括美国脊髓损伤协会损伤量表(AIS)检查、脊髓独立性量表III版(活动子量表)(SCIM-III)、脊髓损伤步行指数II (WISCI-II)、脊髓损伤躯干评估量表(TASS)、五次坐立(5×STS)和2分钟步行测试(2mWT)。结果:康复后3例患者WISCI-II、TASS、5×STS、2mWT均有改善;AIS感官评分没有变化。只有受试者2和3在sim - iii中表现出轻微的改善。所有参与者的WISCI-II均有改善,从3级到9级不等,这被认为是有临床意义的改变。此外,两名参与者的TASS变化超过了最小临床重要差异(MCID) 4分。5×STS的变化超过了所有参与者2.27秒的MCID。这些显著的改善转化为参与者在护理人员的监督下进行独立坐立和使用滚轴框架行走的能力。结论:该临床试验证明了概念验证和有希望的发现,支持我们的康复方案改善感觉运动完全性脊髓损伤患者的功能活动能力,这可能在未来的研究中得到复制。*该研究方案已在Clinical-trials.gov注册(NCT05644171;注册于2022年11月13日。https://clinicaltrials.gov/ct2/show/NCT05644171)。
{"title":"Synergistic integration of epidural spinal cord stimulation with robotic therapy and neurorehabilitation to facilitate functional recovery in chronic sensorimotor complete spinal cord injury: A case series.","authors":"Seng Kwee Wee, Zhi Yan Ng Valerie, Min Wee Phua, Wen Li Lui, Fatimah Misbaah, Rui Xin Justin Ker, Wai Hoe Ng, Kai Rui Wan","doi":"10.1177/27536351251343738","DOIUrl":"10.1177/27536351251343738","url":null,"abstract":"<p><strong>Objective: </strong>To present the rehabilitation considerations in prehabilitation and the rehabilitation phase post spinal cord stimulator implantation; and to evaluate the efficacy of synergistic combination of epidural spinal cord stimulation (SCS) with motor imagery, trunk rehabilitation, robotic and overground gait training in improving mobility in persons with sensorimotor complete spinal cord injury (SCI).</p><p><strong>Design: </strong>A non-controlled before-after clinical trial.</p><p><strong>Methods: </strong>Epidural spinal cord stimulators were implanted into 3 participants with complete thoracic SCI (Thoracic 4, Thoracic 2 and Thoracic 10 respectively). They underwent 1 month of prehabilitation, followed by 7 months of daily rehabilitation post-implantation, consisting of SCS, motor imagery, trunk rehabilitation, robotic therapy and overground gait training. Pre-post assessments include the American Spinal Injury Association Impairment Scale (AIS) examination, Spinal Cord Independence Measure version III (Mobility subscale) (SCIM-III), Walking Index for Spinal Cord Injury II (WISCI-II), Trunk Assessment Scale for Spinal Cord Injury (TASS), Five Times Sit-to-Stand (5×STS) and 2-minute Walk Test (2mWT).</p><p><strong>Results: </strong>Post rehabilitation, there were improvements in WISCI-II, TASS, 5×STS and 2mWT in all 3 participants; and no change in AIS sensory scores. Only participants 2 and 3 exhibited slight improvement in SCIM-III. The WISCI-II of all participants improved, ranging from 3 levels to 9 levels, which was considered a clinically meaningful change. Furthermore, the change in TASS exceeded the minimal clinically important difference (MCID) of 4 points for two participants. The change in 5×STS exceeded the MCID of 2.27 seconds for all participants. These significant improvements translated into the participants' ability to perform sit-to-stand independently and ambulate with a rollator frame under supervision of a carer.</p><p><strong>Conclusion: </strong>This clinical trial demonstrated proof-of-concept and promising findings that support our rehabilitation protocol in improving functional mobility of people with sensorimotor complete SCI, which may be replicated in future studies.*The study protocol was registered with Clinical-trials.gov (NCT05644171; Registered 13 November 2022. https://clinicaltrials.gov/ct2/show/NCT05644171).</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"14 ","pages":"27536351251343738"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meta-Analysis of Goal Setting and Physical Treatment Categorisation for Focal Spasticity Following Stroke or Other Acquired Brain Injury. 卒中或其他获得性脑损伤后局灶性痉挛目标设定和物理治疗分类的meta分析。
0 REHABILITATION Pub Date : 2025-06-19 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251343520
Stephen Ashford, Jorge Jacinto, Klemens Fheodoroff, Lynne Turner-Stokes

Background: Setting goals and planning treatment to attain those goals is often integral to rehabilitation practice, particularly when managing spasticity following stroke or other brain injury. Optimal treatment planning and provision using an algorithm based on mapping goals and treatments, may improve outcome.

Methods: We analysed goal setting and treatment interventions through secondary analysis of goals and related treatments from (a) the Leg Activity measure study, (b) Ankle Contracture data set and (c) the Upper Limb International Spasticity-III study. Total 1207 participants. Goal categories were defined and identified based on a previously published framework: Pain, Involuntary Movement, Contracture Prevention, Active Function (self-performance of tasks), passive function (secondary performance of tasks or personal care). Treatment intervention was then identified per goal category.

Results: Arm spasticity goal categorisation: Pain 302 (22%), Involuntary Movement 166 (12%), Contracture Prevention 208 (15%), Active Function 174 (13%), passive function 501 (37%). Primary interventions identified per category: Pain (Positioning the limb, serial casting), Involuntary Movement (Position the limb, Splinting), Contracture Prevention (Positioning the limb, serial casting, Shoulder support and slings, Splinting), Active Function (Positioning the limb, serial casting, shoulder supports and splinting), passive function (Positioning the limb, serial casting, shoulder supports and splinting). Leg spasticity goal categorisation: Pain 117 (15%), Involuntary Movement 10 (1%), Contracture Prevention 139 (17%), Active Function 356 (44%), passive function 181 (22%). Primary interventions identified per category: Pain (Passive stretch, positioning), Involuntary Movement (Splinting), Contracture Prevention (Positioning, Orthotics, Task Practice), Active Function (Task Practice, Orthotics), passive function (Orthotics, Positioning).

Conclusions: Commonalities in goal categorisation were found in arm and leg. In these cohorts' task-practice interventions to improve active function (walking and transferring) were reported for leg but were not frequently reported for arm rehabilitation. It is suggested that improved treatment planning may result in greater and faster treatment goal attainment and better outcomes.

背景:设定目标和计划治疗以实现这些目标通常是康复实践中不可或缺的一部分,特别是在处理中风或其他脑损伤后的痉挛时。使用基于绘制目标和治疗方法的算法进行最佳治疗计划和提供,可以改善结果。方法:我们通过对(a)腿部活动测量研究、(b)踝关节挛缩数据集和(c)上肢国际痉挛- iii研究的目标和相关治疗进行二次分析,分析目标设定和治疗干预措施。共1207名参与者。目标类别是根据先前发布的框架定义和确定的:疼痛,不自主运动,挛缩预防,主动功能(任务的自我表现),被动功能(任务或个人护理的次要表现)。然后根据目标类别确定治疗干预措施。结果:手臂痉挛目标分类:疼痛302例(22%),不自主运动166例(12%),挛缩预防208例(15%),主动功能174例(13%),被动功能501例(37%)。按类别确定的主要干预措施:疼痛(肢体定位,连续铸造),不自主运动(肢体定位,连续铸造),挛缩预防(肢体定位,连续铸造,肩部支撑和吊带,夹板),主动功能(肢体定位,连续铸造,肩部支撑和夹板),被动功能(肢体定位,连续铸造,肩部支撑和夹板)。腿部痉挛目标分类:疼痛117例(15%),不自主运动10例(1%),挛缩预防139例(17%),主动功能356例(44%),被动功能181例(22%)。每个类别确定的主要干预措施:疼痛(被动拉伸,定位),不自主运动(夹板),挛缩预防(定位,矫形,任务练习),主动功能(任务练习,矫形),被动功能(矫形,定位)。结论:手臂和腿部在目标分类上存在共性。在这些队列中,改善活动功能(行走和移动)的任务练习干预在腿部有报道,但在手臂康复方面很少有报道。建议改进治疗计划可使治疗目标更快更快地实现,并获得更好的治疗效果。
{"title":"Meta-Analysis of Goal Setting and Physical Treatment Categorisation for Focal Spasticity Following Stroke or Other Acquired Brain Injury.","authors":"Stephen Ashford, Jorge Jacinto, Klemens Fheodoroff, Lynne Turner-Stokes","doi":"10.1177/27536351251343520","DOIUrl":"10.1177/27536351251343520","url":null,"abstract":"<p><strong>Background: </strong>Setting goals and planning treatment to attain those goals is often integral to rehabilitation practice, particularly when managing spasticity following stroke or other brain injury. Optimal treatment planning and provision using an algorithm based on mapping goals and treatments, may improve outcome.</p><p><strong>Methods: </strong>We analysed goal setting and treatment interventions through secondary analysis of goals and related treatments from (a) the Leg Activity measure study, (b) Ankle Contracture data set and (c) the Upper Limb International Spasticity-III study. Total 1207 participants. Goal categories were defined and identified based on a previously published framework: Pain, Involuntary Movement, Contracture Prevention, Active Function (self-performance of tasks), passive function (secondary performance of tasks or personal care). Treatment intervention was then identified per goal category.</p><p><strong>Results: </strong><i>Arm spasticity goal categorisation</i>: Pain 302 (22%), Involuntary Movement 166 (12%), Contracture Prevention 208 (15%), Active Function 174 (13%), passive function 501 (37%). <i>Primary interventions identified per category</i>: Pain (Positioning the limb, serial casting), Involuntary Movement (Position the limb, Splinting), Contracture Prevention (Positioning the limb, serial casting, Shoulder support and slings, Splinting), Active Function (Positioning the limb, serial casting, shoulder supports and splinting), passive function (Positioning the limb, serial casting, shoulder supports and splinting). <i>Leg spasticity goal categorisation</i>: Pain 117 (15%), Involuntary Movement 10 (1%), Contracture Prevention 139 (17%), Active Function 356 (44%), passive function 181 (22%). <i>Primary interventions identified per category</i>: Pain (Passive stretch, positioning), Involuntary Movement (Splinting), Contracture Prevention (Positioning, Orthotics, Task Practice), Active Function (Task Practice, Orthotics), passive function (Orthotics, Positioning).</p><p><strong>Conclusions: </strong>Commonalities in goal categorisation were found in arm and leg. In these cohorts' task-practice interventions to improve active function (walking and transferring) were reported for leg but were not frequently reported for arm rehabilitation. It is suggested that improved treatment planning may result in greater and faster treatment goal attainment and better outcomes.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"14 ","pages":"27536351251343520"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric Validation of the Arabic Version of the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES) in Libya. 利比亚阿拉伯版美国肩关节外科医生标准化肩关节评估表(ASES)的心理测量学验证。
0 REHABILITATION Pub Date : 2025-06-13 eCollection Date: 2025-01-01 DOI: 10.1177/27536351251348750
Alhadi M Jahan, Aymen M Elgoneti

Objective: This study aimed to adapt and validate the Arabic version of the American Shoulder and Elbow Surgeons (ASES) Standardized Shoulder Assessment Form for assessing shoulder disabilities in the Libyan-Arab population.

Methods: A cross-sectional study design was employed, involving 108 participants with shoulder conditions from rehabilitation centers in Misrata, Libya. The ASES form underwent translation and cultural adaptation following established guidelines, including forward translation, synthesis, back-translation, expert review, and pilot testing. Psychometric validation included assessments of reliability, convergent and discriminant validity, and agreement using Cronbach's α, Intraclass Correlation Coefficient (ICC), and Bland-Altman analysis.

Results: The Arabic ASES form demonstrated excellent internal consistency (Cronbach's α = .90) and high test-retest reliability (ICC = 0.95). Convergent validity was confirmed by significant correlations with the DASH (r = -.867, P < .001), ADL (r = .522, P < .001), VAS (r = -.480, P < .001), and SF-MPQ (r = -.554, P < .001). Discriminant validity was supported by weak, non-significant correlations with unrelated constructs such as self-efficacy, sleep quality, and stress. Bland-Altman analysis indicated minimal systematic bias between repeated measurements.

Conclusion: The Arabic ASES form is a reliable, valid, and culturally appropriate tool for evaluating shoulder disabilities in Arabic-speaking populations, particularly in Libya. Its cross-cultural validation supports broader applicability across diverse Arabic-speaking contexts, enhancing clinical and research utility.

目的:本研究旨在调整和验证阿拉伯版本的美国肩关节外科医生(ASES)标准肩关节评估表,以评估利比亚-阿拉伯人群的肩关节残疾。方法:采用横断面研究设计,纳入108名来自利比亚米苏拉塔康复中心的肩部疾病患者。根据既定的指导方针,包括正向翻译、综合、反向翻译、专家审查和试点测试,对as表格进行了翻译和文化适应。心理测量验证包括信度、收敛效度和判别效度评估,并使用Cronbach's α、类内相关系数(ICC)和Bland-Altman分析进行一致性评估。结果:阿拉伯文as表具有良好的内部一致性(Cronbach’s α = 0.90)和较高的重测信度(ICC = 0.95)。通过与DASH的显著相关(r = -)证实了收敛效度。867, P r =。522 P r = -。480 P r = -。554, P结论:阿拉伯语as表是评估阿拉伯语人群肩部残疾的可靠、有效和文化上合适的工具,特别是在利比亚。其跨文化验证支持在不同阿拉伯语环境中更广泛的适用性,增强临床和研究效用。
{"title":"Psychometric Validation of the Arabic Version of the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES) in Libya.","authors":"Alhadi M Jahan, Aymen M Elgoneti","doi":"10.1177/27536351251348750","DOIUrl":"10.1177/27536351251348750","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to adapt and validate the Arabic version of the American Shoulder and Elbow Surgeons (ASES) Standardized Shoulder Assessment Form for assessing shoulder disabilities in the Libyan-Arab population.</p><p><strong>Methods: </strong>A cross-sectional study design was employed, involving 108 participants with shoulder conditions from rehabilitation centers in Misrata, Libya. The ASES form underwent translation and cultural adaptation following established guidelines, including forward translation, synthesis, back-translation, expert review, and pilot testing. Psychometric validation included assessments of reliability, convergent and discriminant validity, and agreement using Cronbach's α, Intraclass Correlation Coefficient (ICC), and Bland-Altman analysis.</p><p><strong>Results: </strong>The Arabic ASES form demonstrated excellent internal consistency (Cronbach's α = .90) and high test-retest reliability (ICC = 0.95). Convergent validity was confirmed by significant correlations with the DASH (<i>r</i> = -.867, <i>P</i> < .001), ADL (<i>r</i> = .522, <i>P</i> < .001), VAS (<i>r</i> = -.480, <i>P</i> < .001), and SF-MPQ (<i>r</i> = -.554, <i>P</i> < .001). Discriminant validity was supported by weak, non-significant correlations with unrelated constructs such as self-efficacy, sleep quality, and stress. Bland-Altman analysis indicated minimal systematic bias between repeated measurements.</p><p><strong>Conclusion: </strong>The Arabic ASES form is a reliable, valid, and culturally appropriate tool for evaluating shoulder disabilities in Arabic-speaking populations, particularly in Libya. Its cross-cultural validation supports broader applicability across diverse Arabic-speaking contexts, enhancing clinical and research utility.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"14 ","pages":"27536351251348750"},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Advances in rehabilitation science and practice
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