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Sculpting the Midface and Lower Face: A Novel Biostimulatory Technique Using Hyperdilute Calcium Hydroxylapatite. 塑造中脸和下脸:一种使用超稀钙羟基磷灰石的新型生物刺激技术。
IF 1.9 Pub Date : 2025-08-25 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf104
Kalpna Kay Durairaj, Monalea Yambao, Jacob Linnemann-Heath, Arshiya Dhiman

Background: Facial aging is a multifactorial process characterized by soft tissue atrophy, skeletal remodeling, and degradation of dermal extracellular matrix components such as collagen and elastin. Injectable biostimulators have gained popularity in recent years for their efficacy in reinforcing the structural foundation of the face by stimulating the body's natural regenerative processes.

Objectives: The authors of this study aimed to assess their multidepth injection technique with hyperdilute calcium hydroxylapatite (CaHA-CMC; Radiesse, Merz Aesthetics, Raleigh, NC) for multilayered collagen biostimulation to address laxity, jowling, and skin aging-related changes.

Methods: The authors of this study reviewed the charts of 22 patients who underwent 2 treatment sessions with hyperdilute CaHA-CMC (1:3 ratio) using the author's technique for targeted rejuvenation of the mid and lower face. At each visit, assessments included the Global Aesthetic Improvement Scale (GAIS), patient satisfaction, and rankings of aging parameters of the face measured by 5-point photonumeric scales. Volumetric changes were objectively measured with 3-dimensional (3D) imaging analysis via QuantifiCare's 3D Track software.

Results: Quantitative analysis at Day 150 revealed a significant improvement in cheek volume (P = .0012) and significant reductions in jowl volume, nasolabial fold depth, and marionette line depth (P < .0001, P < .0001, P = .0019, respectively). GAIS evaluations from the treating physician, a blinded evaluator, and patients demonstrated progressive improvement peaking at Day 150.

Conclusions: The results of this study support the safety and efficacy of the author's novel technique with hyperdilute CaHA for lower and midface rejuvenation, further enhancing the utility of biostimulators in aesthetic medicine.

Level of evidence: 4 (Therapeutic).

背景:面部衰老是一个多因素过程,其特征是软组织萎缩、骨骼重塑和真皮细胞外基质成分(如胶原蛋白和弹性蛋白)的降解。近年来,可注射生物刺激剂因其通过刺激人体自然再生过程来增强面部结构基础的功效而受到欢迎。目的:本研究的作者旨在评估他们使用超稀羟基磷灰石钙(CaHA-CMC; Radiesse, Merz Aesthetics, Raleigh, NC)进行多层胶原生物刺激的多深度注射技术,以解决松弛,下巴和皮肤衰老相关的变化。方法:本研究回顾了22例使用超稀释CaHA-CMC(1:3比例)治疗2次的患者的图表,这些患者使用作者的技术进行了中、下面部的靶向年轻化。在每次访问中,评估包括全球审美改善量表(GAIS),患者满意度和面部衰老参数排名,由5点光子数字量表测量。通过QuantifiCare的3D Track软件进行三维成像分析,客观测量体积变化。结果:第150天的定量分析显示,脸颊体积显著改善(P = 0.0012),脸颊体积、鼻唇沟深度和木偶线深度显著减少(P < 0.0001, P < 0.0001, P = 0.0019)。由治疗医师、盲法评估者和患者进行的GAIS评估显示,在第150天达到了进行性改善的峰值。结论:本研究的结果支持了作者利用超稀释CaHA进行面部中下部年轻化的新技术的安全性和有效性,进一步增强了生物刺激剂在美容医学中的应用。证据等级:4(治疗性)。
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引用次数: 0
Technical Aspects of Addressing Lower Buttock Ptosis and Contouring: The Thong Lift Technique. 解决下臀部下垂和轮廓的技术方面:丁字裤提升技术。
IF 1.9 Pub Date : 2025-08-08 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf100
Kishan S Shah, Cameron J Sabet, Paul E Chasan

Background: Recent advancements in buttock aesthetics have largely focused on fat transfer, implants, and belt line lifts, all of which overlook the specific needs of the lower pole of the buttock, especially the inferomedial region. These areas are characterized by ptosis, exaggerated infragluteal creasing, and an L-shaped/boxy appearance, requiring targeted intervention.

Objectives: The authors of this study aim to investigate the utilization of an infragluteal thigh lift, termed the thong lift (TL), to correct isolated lower buttock ptosis and L-shaped/boxy buttock deformity.

Methods: A retrospective chart review and patient survey was conducted for consecutive patients who underwent the TL procedure at a single surgical center between January 2017 and April 2024. Clinical data collected included patient demographics, indications, surgical history, and postoperative outcomes. Patients were also administered a standardized satisfaction survey following the procedure to rate outcomes.

Results: In total, 26 consecutive female patients (mean age: 48.5 years, range, 27-69 years) underwent the TL procedure during the study period. The average follow-up was 48.7 months. Patient satisfaction was high, with contour and scar quality rated as "good" to "excellent," on average. All patients (100%) reported improved aesthetic appearance and satisfaction with their outcomes. Only minor complications were recorded (15.4%), all of which were resolved.

Conclusions: Based on the results of this study, the TL is a promising technique that can be utilized to correct lower buttock ptosis and contour irregularities overlooked by traditional techniques, offering a targeted solution with minimal complications and high patient satisfaction.

Level of evidence 4 therapeutic:

背景:最近臀部美学的进展主要集中在脂肪移植,植入和皮带线提升,所有这些都忽略了臀部下极,特别是内侧区域的特定需求。这些区域的特征是上睑下垂,骨折过度皱褶,l形/方形外观,需要有针对性的干预。目的:本研究的作者旨在探讨使用不骨折的大腿提升,称为丁字裤提升(TL),纠正孤立的下臀部下垂和l型/方形臀部畸形。方法:对2017年1月至2024年4月在同一手术中心连续接受TL手术的患者进行回顾性图表回顾和患者调查。收集的临床资料包括患者人口统计学、适应症、手术史和术后结果。在手术后,患者还接受了一项标准化的满意度调查,以评估结果。结果:在研究期间,共有26例连续女性患者(平均年龄48.5岁,范围27-69岁)接受了TL手术。平均随访48.7个月。患者满意度很高,轮廓和疤痕质量平均被评为“好”到“优秀”。所有患者(100%)报告美学外观改善和对结果的满意度。仅发生轻微并发症(15.4%),均得到解决。结论:基于本研究的结果,TL是一种很有前途的技术,可以用于纠正传统技术忽略的下臀下垂和轮廓不规则,提供了一个有针对性的解决方案,并发症最少,患者满意度高。证据等级4:治疗性:
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引用次数: 0
Severe Complications Due to Biopolymers in a Patient With Autoimmune Disease: A Case Report and Review of the Literature. 自身免疫性疾病患者因生物聚合物引起的严重并发症:1例报告和文献复习
IF 1.9 Pub Date : 2025-08-04 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf099
Andrés Hormaza-Jaramillo, Daniela Peñaloza Gonzalez, Sara Alejandra Benavides-Ibarra, Natalia Calvache Hernandez, Liliana Eugenia Muñoz Garcia, Alejandra Hidalgo Cardona, Jackeline Murrillo-Mera

Biopolymers are frequently used for aesthetic or reconstructive purposes, often without adequate consideration of the potential long-term health complications they may cause. The use of these substances has been associated with autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA syndrome); however, the existing literature is limited, and there is currently no clear consensus regarding its management. This case report aims to describe a case of severe biopolymer-induced inflammatory disease in a patient with a diagnosis of rheumatoid arthritis, highlighting both the diagnostic and therapeutic approaches. This case report examines a 58-year-old female patient with a history of biopolymer application to the gluteal and facial region 20 years before and a diagnosis of rheumatoid arthritis for the past 2 years. She presented with severe inflammatory skin lesions with worsening arthralgia. An MRI scan revealed exogenous material with signs of severe inflammation of the surrounding tissues, and a biopsy was consistent with foreign body granulomas with a "Swiss cheese" morphology. The patient was hospitalized and received multidisciplinary management, achieving an excellent clinical response. This case highlights the importance of a comprehensive evaluation and a multidisciplinary approach in patients with autoimmune disease and previous exposure to biopolymers. The coexistence of autoimmune diseases can aggravate the inflammatory response, suggesting the need for additional studies exploring this interaction and its prognostic impact. Level of Evidence: 5 (Risk).

生物聚合物经常用于美学或重建目的,通常没有充分考虑它们可能引起的潜在的长期健康并发症。这些物质的使用与佐剂诱导的自身免疫/自身炎症综合征(ASIA综合征)有关;然而,现有文献有限,目前对其管理尚无明确的共识。本病例报告旨在描述一个诊断为类风湿关节炎的患者中严重的生物聚合物诱导炎症性疾病的病例,强调诊断和治疗方法。本病例报告检查了一名58岁女性患者,20年前曾在臀部和面部区域应用生物聚合物,过去2年诊断为类风湿关节炎。她表现为严重的炎症性皮肤病变,伴有关节痛的恶化。MRI扫描显示外源性物质伴周围组织严重炎症征象,活检符合“瑞士奶酪”形态的异物肉芽肿。患者住院并接受多学科治疗,取得了良好的临床疗效。本病例强调了对自身免疫性疾病和既往接触过生物聚合物的患者进行综合评估和多学科方法的重要性。自身免疫性疾病的共存可加重炎症反应,提示需要进一步研究这种相互作用及其预后影响。证据等级:5(风险)。
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引用次数: 0
Content Analysis of Instagram Stories of Top Plastic Surgeons. 顶级整形医生Instagram故事的内容分析。
IF 1.9 Pub Date : 2025-07-31 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf051
Olivia C MacIntyre, Colton Boudreau, Alison Wong

Instagram stories (Meta, Menlo Park, CA) are posted at higher volumes and incite increased engagement for accounts. This is because of Instagram's algorithm, which typically only shows static posts to 10% of an account's followers. Given the importance of social media in cosmetic surgery practices, a detailed analysis of trends is useful in guiding plastic surgeon marketing regimes. The aim of the authors of this study is to provide a detailed analysis of Instagram story content posted by top 100 most-followed plastic surgeons in the world. One hundred plastic surgery Instagram accounts in the world were identified by their total number of followers and using the keywords "plastic," "cosmetic," "aesthetic," and "surgeon." Accounts of each surgeon were monitored daily over 1 week, with story content categorically logged. Broad categories included personal, educational, surgical, and engagement, which were further divided into subcategories. Qualitative and quantitative measures were used to assess demographics and trends. The average number of followers by the top accounts was 437,917 ± 36,216. The majority of accounts were located in North America (64%). The average number of stories posted each week was 28.2 ± 3.7, with the highest number posted on Friday (5.01) and the lowest on Saturday (2.67). The most common content of stories posted was related to surgical procedures (57.6%), contributing 1577 total stories. In this descriptive study, the authors provide insight into the nature of Instagram story content posted by top-followed plastic surgeons in the world, providing guidance to new and existing plastic surgeons in their social media practices. Level of Evidence: 5 (Therapeutic).

Instagram故事(Meta, Menlo Park, CA)的发布量更高,并激发了账户的参与度。这是因为Instagram的算法,它通常只向账户10%的关注者显示静态帖子。鉴于社交媒体在整容手术中的重要性,对趋势的详细分析有助于指导整形外科医生的营销制度。本研究作者的目的是对世界上最受关注的前100名整形外科医生发布的Instagram故事内容进行详细分析。世界上100个整形手术Instagram账户根据他们的粉丝总数和关键词“整形”、“美容”、“美学”和“外科医生”进行了识别。在一周的时间里,每天监测每位外科医生的账户,并分类记录故事内容。广泛的分类包括个人、教育、外科和订婚,并进一步细分为子类别。采用了定性和定量措施来评估人口统计和趋势。排名前几位的平均粉丝数为437917±36216。大多数客户位于北美(64%)。每周平均发布的故事数为28.2±3.7篇,周五最多(5.01篇),周六最少(2.67篇)。与手术相关的故事内容最多(57.6%),共1577篇。在这项描述性研究中,作者深入了解了世界上最受关注的整形外科医生发布的Instagram故事内容的性质,为新的和现有的整形外科医生在社交媒体上的实践提供指导。证据等级:5(治疗性)。
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引用次数: 0
Surgical Emphysema Post Liposuction Overseas: A Case Report. 国外吸脂术后肺气肿1例报告。
IF 1.9 Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf085
Hannah Cook, Samim Ghorbanian, Marios Erotocritou, Lucy Coull, Yildirim Oezdogan

Liposuction is the most common surgical procedure performed globally. It is generally associated with low rates of major complications. Cosmetic surgery tourism has seen a steep incline in popularity and is often favorable to patients because of lower costs. However, it can be associated with higher complication rates and poorer follow-up. In this case report, the authors describe a case of severe symptomatic subcutaneous emphysema following air travel post liposuction. A 49-year-old male presented to the emergency department in the United Kingdom with pain, bruising, and swelling post liposuction to the chest, abdomen, and flanks. At Day 5 postoperatively, the patient embarked on a 5-hour plane journey, during which they experienced a significant increase in pain and swelling. On examination, there was audible crepitus at the upper abdomen and chest. A computerized tomography scan revealed extensive subcutaneous emphysema with associated skin thickening, subcutaneous fat stranding, and fluid. In this case, subcutaneous emphysema is likely a direct result of surgical technique. This case is unique in the severity of the symptoms described and the presumed role of air travel in their exacerbation. It is important that patients are adequately counseled on risks that may arise because of flying in the close postoperative period. Another issue highlighted is the increasing number of presentations to UK public hospitals following cosmetic tourism. Subcutaneous emphysema is a recognized but rare complication of liposuction. Patients should be adequately informed of adverse events that can arise following cosmetic surgery and subsequent travel. Level of Evidence: 4 (Therapeutic).

吸脂是全球最常见的外科手术。它通常与低发生率的主要并发症有关。整容旅游的受欢迎程度急剧上升,由于费用较低,通常对患者有利。然而,它可能与较高的并发症发生率和较差的随访有关。在这个病例报告中,作者描述了一个病例严重症状皮下肺气肿后,航空旅行后吸脂。一名49岁男性在英国因胸部、腹部和腹部吸脂后疼痛、瘀伤和肿胀而就诊于急诊室。术后第5天,患者乘坐了5个小时的飞机,在此期间,他们经历了明显的疼痛和肿胀。经检查,上腹部及胸部有可闻的捻音。计算机断层扫描显示广泛的皮下肺气肿伴皮肤增厚、皮下脂肪堆积和积液。在这种情况下,皮下肺气肿可能是手术技术的直接结果。该病例在所描述的症状的严重程度和空中旅行在其恶化中的假定作用方面是独一无二的。重要的是,患者应充分了解术后飞行可能产生的风险。另一个突出的问题是,随着美容旅游的到来,英国公立医院的美容讲座越来越多。皮下肺气肿是吸脂术中一种公认但罕见的并发症。患者应充分了解在整容手术和随后的旅行后可能出现的不良事件。证据等级:4(治疗性)。
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引用次数: 0
Drainless Lower Body Lift With Large-Volume Liposuction and Adjunctive Procedures: A Single-Surgeon Retrospective Review of 137 Consecutive Patients and Outcomes. 无排水下体提升与大容量吸脂和辅助手术:对137例连续患者和结果的单一外科医生回顾性回顾。
IF 1.9 Pub Date : 2025-07-26 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf095
Samer W Cabbabe

Background: Lower body lift (LBL) is a powerful 360° contouring procedure, most commonly performed after massive weight loss.

Objectives: In this study, the author reviews outcomes of a large series of drainless LBL procedures performed by a single surgeon combined with high-volume liposuction and adjunctive body procedures. The surgeon's technique is described.

Methods: A retrospective review was conducted on 137 consecutive patients who underwent drainless LBL between 2023 and 2025 by a single surgeon. Data collected included demographics, adjunctive procedures, liposuction volumes, fat grafting, hemoglobin levels, estimated blood loss (EBL), complications, and reoperations. All patients received preoperative optimization, including iron supplementation, and a multimodal perioperative protocol was employed. No drains were used for the procedures.

Results: The mean age was 44.5 years, and the mean BMI was 26.8 kg/m2. Average liposuction volume was 2518 cc, with 1976 cc of pure fat removed. Mean fat transfer volumes were 1075 cc (buttocks) and 628 cc (breasts). Average EBL was 572 cc. Adjunctive procedures included Brazilian butt lift (99.3%), 360 liposuction (96.4%), fleur-de-lis tummy tuck (41.6%), mastopexy (29.2%), and others. The complication rate was 6.6%, with 0.7% requiring reoperation. Complications included hematoma (n = 1), deep vein thrombosis (n = 1), transfusions (n = 2), and delayed healing (n = 5). No seromas or revisions were reported.

Conclusions: Drainless LBL with progressive tension sutures, scarpal flap preservation, and limited undermining is a safe and effective approach and can be combined with high-volume liposuction and multiple adjunctive procedures. This technique resulted in lower complication and revision rates compared with previously published series.

Level of evidence 4 therapeutic:

背景:下体提升(LBL)是一种强大的360°轮廓手术,最常在大量减肥后进行。目的:在本研究中,作者回顾了由一名外科医生联合大容量吸脂和辅助体手术进行的一系列无引流LBL手术的结果。描述了外科医生的技术。方法:回顾性分析在2023年至2025年间由同一外科医生连续行无引流LBL的137例患者。收集的数据包括人口统计学、辅助手术、吸脂量、脂肪移植、血红蛋白水平、估计失血量(EBL)、并发症和再手术。所有患者均接受术前优化,包括补铁,并采用多模式围手术期方案。手术过程中没有使用排水管。结果:平均年龄44.5岁,平均BMI为26.8 kg/m2。平均吸脂量为2518 cc,纯脂肪去除量为1976 cc。平均脂肪转移量为1075毫升(臀部)和628毫升(乳房)。平均EBL为572 cc。辅助手术包括巴西提臀术(99.3%)、360度吸脂术(96.4%)、鸢尾花腹部除皱术(41.6%)、乳房固定术(29.2%)等。并发症发生率为6.6%,再次手术率为0.7%。并发症包括血肿(n = 1)、深静脉血栓(n = 1)、输血(n = 2)和延迟愈合(n = 5)。无血清肿或修复报告。结论:无引流LBL加渐进式张力缝合、保留皮瓣、有限破坏是一种安全有效的方法,可联合大容量吸脂及多种辅助手术。与先前发表的系列相比,该技术的并发症和翻修率较低。证据等级4:治疗性:
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引用次数: 0
Inferior Pole Adipose Dermal Flap for Breast Reconstruction: A Novel Oncoplastic Technique for Breast-Conserving Surgery. 下极脂肪真皮皮瓣用于乳房重建:一种新的保乳手术肿瘤整形技术。
IF 1.9 Pub Date : 2025-07-23 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf096
Francesco Klinger, Riccardo Di Giuli, Alessandra Veronesi, Barbara Catania, Stefano Vaccari, Valeria Bandi, Marco Klinger, Valeriano Vinci

Background: Breast cancer is a prevalent malignancy among women, and advancements in treatment have shifted focus to enhancing both survival and quality of life. Oncoplastic surgery integrates oncological safety with aesthetic considerations.

Objectives: The authors of this study aim to evaluate the efficacy of the inferior pole adipose dermal (IPAD) flap for lower pole reconstruction in breast-conserving surgery (BCS).

Methods: A retrospective cohort study was conducted involving patients who underwent BCS with IPAD flap reconstruction. Inclusion criteria comprised female patients over 18 years with at least 12 months of follow-up. Data collected included demographics, clinical history, surgical details, complications, and patient satisfaction, assessed using the Visual Analog Scale (VAS).

Results: The study included 12 patients with a mean age of 52.7 years and a mean BMI of 28. Four patients (33.3%) required integration of a perforator flap for additional volume. No major complications, such as infections or flap necrosis, were observed. Minor complications included lower pole retraction (16.6%) and inferior dehiscence (8.3%). Patient satisfaction was high (VAS 7.5), and aesthetic outcomes were rated positively by surgeons (7.2). Adjuvant radiotherapy did not adversely affect flap viability.

Conclusions: The IPAD flap may be a viable and effective technique for lower pole reconstruction in BCS. This technique is particularly beneficial for patients with adequate breast volume. The authors of this study underscore the importance of personalized surgical planning and a multidisciplinary approach to optimizing breast cancer treatment.

Level of evidence 4 therapeutic:

背景:乳腺癌是女性中普遍存在的恶性肿瘤,治疗的进步已经将重点转移到提高生存率和生活质量上。肿瘤整形手术将肿瘤安全性与美学考虑相结合。目的:探讨下极脂肪真皮(IPAD)瓣在保乳手术(BCS)下极重建中的应用效果。方法:对行BCS伴IPAD皮瓣重建的患者进行回顾性队列研究。纳入标准包括18岁以上的女性患者,随访至少12个月。收集的数据包括人口统计学、临床病史、手术细节、并发症和患者满意度,使用视觉模拟量表(VAS)进行评估。结果:研究纳入12例患者,平均年龄52.7岁,平均BMI为28。4例患者(33.3%)需要整合穿支皮瓣以增加体积。无重大并发症,如感染或皮瓣坏死。轻微并发症包括下极回缩(16.6%)和下裂孔(8.3%)。患者满意度高(VAS 7.5),外科医生对美学结果的评价为积极(7.2)。辅助放疗对皮瓣存活无不良影响。结论:IPAD皮瓣是一种可行、有效的BCS下极重建技术。这项技术对乳房容量充足的患者尤其有益。这项研究的作者强调了个性化手术计划和多学科方法优化乳腺癌治疗的重要性。证据等级4:治疗性:
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引用次数: 0
A Systematic Review of Adipose-Derived Cell Therapies on Skin Quality. 脂肪源性细胞治疗对皮肤质量的系统评价。
IF 1.9 Pub Date : 2025-07-18 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf098
Jeewon Chon, Shea E Randall, Taylor A Schumann, Antoinette T Nguyen, Anmar Abu-Romman, Bradley A Melnick, Rahim Laiwalla, Rena A Li, Robert D Galiano

Skin aging leads to changes such as dyschromia, rhytids, dermal atrophy, and reduced elasticity. Adipose-derived cell therapies (ADCTs), including stromal vascular fraction (SVF), adipose-derived stem cells (ADSCs), and adipose-derived mesenchymal stem cells (AD-MSCs), have gained attention for their regenerative potential. In this systematic review, the authors aim to evaluate the effectiveness of ADCT in improving skin quality such as elasticity, texture, pigmentation, and rhytid reduction. This systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, with a comprehensive search conducted across PubMed (National Library of Medicine, Bethesda, MD), Embase (Elsevier, Amsterdam, the Netherlands), and Scopus (Elsevier). The authors of eligible studies must have assessed skin quality outcomes, such as rhytids, dyschromia, texture, and elasticity. Data on study design, treatment protocols, and outcomes were extracted. Risk of bias was assessed using the Cochrane RoB 2 tool (Cochrane, London, United Kingdom). Meta-analyses were conducted where appropriate. Seventeen studies met inclusion criteria. Rhytid severity decreased with SVF and ADSC-conditioned medium, particularly in periorbital and nasolabial regions. However, the authors of a meta-analysis of 2 studies showed nonsignificant reduction in rhytids (P = .12, I 2 = 81%), and melanin index results were inconsistent. Combination therapies (eg, SVF with laser or platelet-rich plasma) outperformed SVF alone. Heterogeneity in follow-up duration, treatment protocols, and assessment tools limited direct comparisons. ADCTs show promise as a minimally invasive approach to enhance skin quality. However, variability across studies limits definitive conclusions. Standardized protocols, objective assessment tools, and long-term follow-up are needed to validate them as a reliable skin rejuvenation therapy. Future research should focus on objective assessment tools and larger sample sizes to establish ADCT as a viable skin rejuvenation therapy. Level of Evidence: 3 (Therapeutic).

皮肤老化导致的变化,如色素沉着,心律失常,皮肤萎缩,并降低弹性。脂肪源性细胞疗法(adct),包括基质血管组分(SVF)、脂肪源性干细胞(ADSCs)和脂肪源性间充质干细胞(AD-MSCs),因其再生潜力而受到关注。在这篇系统综述中,作者旨在评估ADCT在改善皮肤质量方面的有效性,如弹性、质地、色素沉着和减少纹。本系统评价遵循系统评价和荟萃分析指南的首选报告项目进行,并在PubMed(美国国家医学图书馆,Bethesda, MD)、Embase(荷兰爱思唯尔,阿姆斯特丹)和Scopus(爱思唯尔)中进行了全面搜索。符合条件的研究的作者必须评估皮肤质量结果,如心律失常、色差、质地和弹性。提取有关研究设计、治疗方案和结果的数据。使用Cochrane RoB 2工具(Cochrane,伦敦,英国)评估偏倚风险。适当时进行meta分析。17项研究符合纳入标准。在SVF和adsc条件培养基中,特别是在眶周和鼻唇区,节律严重程度降低。然而,对2项研究进行荟萃分析的作者显示,心律节律无显著降低(P = 0.12, I 2 = 81%),黑色素指数结果不一致。联合治疗(例如,SVF与激光或富血小板血浆)优于单独SVF。随访时间、治疗方案和评估工具的异质性限制了直接比较。adct有望作为一种微创方法来改善皮肤质量。然而,研究之间的差异限制了明确的结论。需要标准化的方案、客观的评估工具和长期的随访来验证它们是一种可靠的皮肤年轻化疗法。未来的研究应侧重于客观的评估工具和更大的样本量,以确定ADCT作为可行的皮肤年轻化治疗。证据等级:3(治疗性)。
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引用次数: 0
Exosomes in Plastic Surgery: An Expert Video Roundtable Discussion. 外泌体在整形外科:专家视频圆桌讨论。
IF 1.9 Pub Date : 2025-07-12 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf093
Steven Cohen, Brannon Claytor, Diane Duncan
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引用次数: 0
A Novel Nonsurgical Smooth Thread Technique to Correct Gummy Smiles. 一种新型的非手术光滑线技术矫正软性微笑。
IF 1.9 Pub Date : 2025-07-12 eCollection Date: 2025-01-01 DOI: 10.1093/asjof/ojaf094
Fabiola Inés Carrasco Avilés, Maurizio Cavallini, Barbara Claysset, Vicenta María Llorca Pérez, Mauro Raichi

Background: "Gummy smile" describes the aesthetically unappealing display of gums that extends more than 2 to 3 mm when individuals smile. The multifactorial etiology of the gummy smile leads to various surgical and nonsurgical treatment strategies, including orthodontic therapies, lip fillers, and primarily botulinum toxin as a nonsurgical treatment.

Objectives: In this paper, the authors present the preliminary report of a novel, minimally invasive, and non-neurotoxic treatment option for gummy smiles based on the insertion of smooth-surfaced resorbable polydioxanone threads along the vectors of the lip elevator muscles, offering long-lasting satisfactory aesthetic outcomes.

Methods: The proposed subcutaneous thread insertion technique utilizes 23 G, 38 mm cannulas with 14 smooth threads per cannula. Twenty-two female patients with subjectively distressing gummy smiles have been treated so far. The correction of gummy smiles is rapid and has been documented for up to 18 months, with the most protracted case lasting 20 months. The first cannula is positioned 1.5 cm from the labial commissure and 0.5 cm above it, following the vector of the orbicularis oris muscle from the modiolus to the upper white lip. The second cannula targets the levator labii superioris muscle vector, entering from the modiolus, and the third cannula follows the zygomaticus major and zygomaticus minor muscle vectors. The insertion points are the same for the first, second, and third cannula. The fourth cannula is inserted 2 cm from the insertion point of the first, second, and third cannulas toward the premasseteric area and the internal corner of the eye, crossing the third thread in a crossed pattern. Only the 2 threads along the levator labii superioris and orbicularis oris vectors were inserted in 1 of the 22 treated patients, who displayed no molar teeth exposure while smiling.

Results: No novel excessive gingival display has occurred in the 22 ambulatory patients treated so far for 9 to 12 months. In the patients treated so far, the mean distances between the diagnostic reference points decreased by 0.85 and 1.25 mm after 2 and 6 weeks, respectively, with negligible pain during the procedure and high satisfaction among all patients.

Conclusions: The proposed smooth thread technique could be a technically convenient and minimally invasive option for addressing disturbing gummy smile problems.

Level of evidence 4 therapeutic:

背景:“Gummy smile”指的是当人们微笑时,牙龈延伸超过2到3毫米,这在美学上并不吸引人。牙龈微笑的多因素病因导致了各种手术和非手术治疗策略,包括正畸治疗,嘴唇填充物,主要是肉毒杆菌毒素作为非手术治疗。目的:在本文中,作者提出了一种新颖的、微创的、无神经毒性的治疗方法,该方法基于沿唇提肌矢量插入表面光滑的可吸收聚二恶酮线,提供持久满意的美学效果。方法:采用23g, 38mm套管,每套管14根光滑螺纹。到目前为止,已经治疗了22名主观痛苦的女性患者。矫正笑容的速度很快,有记录的时间长达18个月,最长的案例持续了20个月。第一个套管位于离唇连口1.5厘米,在唇连口上方0.5厘米处,沿着口轮匝肌的矢量从唇动肌到上白唇。第二条套管以提上唇肌为目标,从颧大肌进入,第三条套管沿颧大肌和颧小肌进入。第一、第二和第三根插管的插入点是相同的。将第四根套管从第一、第二、第三根套管的插入点向咬肌前区和眼内角方向插入2cm处,以交叉方式穿过第三根线。22例患者中有1例微笑时无磨牙外露,仅沿上唇提肌和口轮匝肌载体插入2根线。结果:22例门诊患者治疗9 ~ 12个月未出现新的过度牙龈显示。到目前为止,在接受治疗的患者中,诊断参考点之间的平均距离在2周和6周后分别减少了0.85和1.25 mm,手术过程中疼痛可以忽略,所有患者的满意度都很高。结论:所提出的光滑线技术是一种技术上方便、微创的解决令人不安的粘笑问题的选择。证据等级4:治疗性:
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引用次数: 0
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Aesthetic surgery journal. Open forum
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