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Uptake of Pneumococcal Vaccines Among U.S. Adults After 2022 Update to Recommendations 2022年后美国成人肺炎球菌疫苗接种建议更新
Pub Date : 2025-06-25 DOI: 10.1016/j.focus.2025.100384
Ahuva Averin MPP , Jeffrey Vietri PhD , Adriano Arguedas Mohs MD , Sarah J. Willis PhD, MPH , Alexander Lonshteyn PhD , Derek Weycker PhD

Introduction

Updated recommendations for adult pneumococcal vaccination in the U.S. (publication date: January 27, 2022) incorporated 2 new vaccines (15- and 20-valent pneumococcal conjugate vaccines), removed 13-valent pneumococcal conjugate vaccine, and called for pneumococcal conjugate vaccine use among immunocompetent adults aged 19–64 years with certain medical conditions. This study assessed uptake of recommendations and disparities in uptake across subgroups of adults.

Methods

A retrospective cohort design and data from Optum’s deidentified Clinformatics Data Mart Database were employed. Study population comprised all adults aged ≥65 years and adults aged 19–64 years with ≥1 chronic (at-risk) or immunocompromising (high-risk) condition. Vaccine uptake (including 23-valent pneumococcal polysaccharide vaccine) was estimated using the Kaplan–Meier method.

Results

During 21-month follow-up period, 13.2% of adults (n=6.8 million) received pneumococcal vaccine, mostly 20-valent pneumococcal conjugate vaccine (9.6%). By age/risk conditions, 20-valent pneumococcal conjugate vaccine uptake was highest among adults aged 65–66 years (23.8%) and at-risk/high-risk adults aged 60–64 years (12.1%) and lowest among at-risk/high-risk adults aged 19–49 years (4.7%). By immunization history, 20-valent pneumococcal conjugate vaccine uptake was highest among adults with a history of 23-valent pneumococcal polysaccharide vaccine uptake only (15.1%) or 13-valent pneumococcal conjugate vaccine uptake only (10.6%) and lowest among those without prior pneumococcal vaccination (8.7%) or with a history of 13-valent pneumococcal conjugate vaccine + 23-valent pneumococcal polysaccharide vaccine uptake (7.9%).

Conclusions

Fewer than ∼1 in 7 U.S. adults received 20-valent pneumococcal conjugate vaccine in the first 21 months after the updated recommendations. Uptake was lower among at-risk/high-risk adults aged <60 years, adults aged ≥75 years, and adults without prior pneumococcal vaccination. Routine evaluation of vaccination status by providers and additional strategies to increase uptake of recommend vaccines are warranted.
美国更新了成人肺炎球菌疫苗接种建议(发布日期:2022年1月27日),纳入了两种新疫苗(15价和20价肺炎球菌结合疫苗),取消了13价肺炎球菌结合疫苗,并呼吁在19-64岁具有某些医疗条件的免疫能力成年人中使用肺炎球菌结合疫苗。本研究评估了成人亚组对建议的接受情况和接受情况的差异。方法采用回顾性队列设计,数据来自Optum的鉴别临床数据集市数据库。研究人群包括所有年龄≥65岁的成年人和年龄在19-64岁之间且有≥1种慢性(高危)或免疫功能低下(高危)疾病的成年人。使用Kaplan-Meier法估计疫苗摄取(包括23价肺炎球菌多糖疫苗)。结果在21个月的随访期间,有13.2%的成人(n= 680万)接种了肺炎球菌疫苗,其中以20价肺炎球菌结合疫苗为主(9.6%)。按年龄/危险条件划分,20价肺炎球菌结合疫苗的接种率在65-66岁的成年人中最高(23.8%),在60-64岁的危险/高危成年人中最高(12.1%),在19-49岁的危险/高危成年人中最低(4.7%)。根据免疫史,仅接种23价肺炎球菌多糖疫苗(15.1%)或仅接种13价肺炎球菌结合疫苗(10.6%)的成年人对20价肺炎球菌结合疫苗的接种率最高,未接种过肺炎球菌疫苗(8.7%)或接种过13价肺炎球菌结合疫苗+ 23价肺炎球菌多糖疫苗(7.9%)的成年人对20价肺炎球菌结合疫苗的接种率最低。结论:在更新建议后的前21个月内,不到1 / 7的美国成年人接种了20价肺炎球菌结合疫苗。在60岁、≥75岁和未接种肺炎球菌疫苗的高危成人中,吸收率较低。有必要对提供者的疫苗接种状况进行常规评估,并采取额外的战略来增加推荐疫苗的接受。
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引用次数: 0
A Multi-Institutional Evaluation of Billing for Tobacco-Cessation Services: Opportunities to Improve Quality and Enhance Revenue Capture 戒烟服务收费的多机构评估:提高质量和增加收入的机会
Pub Date : 2025-06-20 DOI: 10.1016/j.focus.2025.100379
Edward Anselm MD , Derek J. Baughman MD , Marcus Rauhut MS , Taylor Martin DO, MPH , Ishan Mahajan , Allison B. McCoy PhD
A recent paper identified significant gaps in billing for tobacco-cessation services for a multihospital health system. Underbilling can reflect poor billing practices, low rates of tobacco-cessation counseling, or a combination of both. The study design was applied to 2 academic medical centers. Deidentified data from the electronic medical records systems were used to identify adult tobacco users and their insurance coverage for patients who had visits to primary care clinics. The proportion of office visits where cessation services were billed was calculated. An economic evaluation of the missed counseling opportunities was based on insurance type and a fee-for-service-payment model. Billing of cessation services is consistently below 2% across the medical centers studied, suggesting substantial opportunities to improve quality and increase revenue. The prevalence of tobacco use in the patient populations studied was significantly lower than reported for that state by the Centers for Disease Control and Prevention.
最近的一篇论文指出,多医院卫生系统在戒烟服务收费方面存在重大差距。低收费可能反映了不良的收费做法,戒烟咨询率低,或两者兼而有之。本研究设计应用于2个学术医学中心。来自电子医疗记录系统的未识别数据用于识别到初级保健诊所就诊的成年烟草使用者及其保险范围。计算了戒烟服务收费的办公室就诊比例。对错过的咨询机会的经济评估是基于保险类型和按服务付费模式。在研究的医疗中心中,戒烟服务的收费一直低于2%,这表明有很大的机会提高质量和增加收入。在被研究的患者人群中,烟草使用的流行率明显低于疾病控制和预防中心对该州的报告。
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引用次数: 0
Duration of Breastfeeding in Infancy and Levels of Central Adiposity and Systemic Inflammation in Early Middle Adulthood 婴儿期母乳喂养时间与中年早期中枢性肥胖和全身性炎症水平的关系
Pub Date : 2025-06-10 DOI: 10.1016/j.focus.2025.100375
Thomas W. McDade PhD , Jessica A. Polos PhD , Kiarri N. Kershaw PhD , Taylor W. Hargrove PhD , Stephanie M. Koning PhD

Introduction

Overweight, obesity, and systemic inflammation contribute to chronic degenerative diseases that are major public health burdens associated with aging. This longitudinal cohort study investigates whether the duration of breastfeeding in infancy predicts waist circumference and chronic systemic inflammation in early middle adulthood.

Methods

Survey-weighted regression models were implemented with data from the National Longitudinal Study of Adolescent to Adult Health, a nationally representative sample of adults (aged 33–44 years) with information on breastfeeding history as well as measures of waist circumference, C-reactive protein, and interleukin 6. Analyses focused on 3,417 and 3,570 participants with C-reactive protein and interleukin 6 measurements, respectively. Fixed-effects regression models were also used to analyze between-sibling differences in breastfeeding duration, waist circumference, and C-reactive protein/interleukin 6. C-reactive protein and interleukin 6 were quantified in serum with highly sensitive particle-enhanced nephelometric and electrochemiluminescent immunoassays, respectively.

Results

Longer duration of breastfeeding was associated with significantly lower waist circumference and lower C-reactive protein. Results were similar for interleukin 6 but statistically weaker. For individuals who were breastfed for 6–12 months and those not at all, marginal mean waist circumference was 94.8 cm (95% CI=92.5, 97.1) and 101.7 cm (95% CI=100.2, 103.2), respectively. Marginal mean C-reactive protein was 1.59 mg/L (95% CI=1.38, 1.84) versus 2.10 mg/L (95% CI=1.97, 2.24). Waist circumference mediated 57.3%–93.8% of the associations between breastfeeding duration and C-reactive protein, depending on duration category. Breastfeeding duration was negatively associated with waist circumference and inflammation in sibling comparisons, but estimates were imprecise and not statistically significant.

Conclusions

The convergence of obesogenic environments and low uptake of breastfeeding for cohorts born after the historical nadir of breastfeeding in the U.S. may contribute to epidemics of overweight/obesity and chronic inflammation that presage risk for chronic degenerative diseases of aging.
超重、肥胖和全身性炎症可导致慢性退行性疾病,这些疾病是与衰老相关的主要公共卫生负担。这项纵向队列研究调查了婴儿期母乳喂养的持续时间是否可以预测中年早期的腰围和慢性全身性炎症。方法采用调查加权回归模型,数据来自全国青少年到成人健康纵向研究,这是一个具有全国代表性的成年人样本(33-44岁),包括母乳喂养史、腰围、c反应蛋白和白细胞介素6的测量数据。分析集中在分别测量c反应蛋白和白细胞介素6的3,417和3,570名参与者身上。固定效应回归模型还用于分析兄弟姐妹之间母乳喂养时间、腰围和c反应蛋白/白细胞介素6的差异。采用高灵敏度粒子增强浊度法和电化学发光免疫法分别定量血清中的c反应蛋白和白细胞介素6。结果母乳喂养时间越长,腰围越小,c反应蛋白含量越低。白细胞介素6的结果相似,但在统计学上较弱。对于母乳喂养6-12个月和完全不母乳喂养的个体,边际平均腰围分别为94.8 cm (95% CI=92.5, 97.1)和101.7 cm (95% CI=100.2, 103.2)。边际平均c反应蛋白分别为1.59 mg/L (95% CI=1.38, 1.84)和2.10 mg/L (95% CI=1.97, 2.24)。腰围介导了母乳喂养持续时间和c反应蛋白之间57.3%-93.8%的关联,具体取决于持续时间类别。在兄弟姐妹比较中,母乳喂养时间与腰围和炎症呈负相关,但估计不准确,没有统计学意义。结论:在美国母乳喂养历史最低点之后出生的人群中,肥胖环境的趋同和母乳喂养的低吸收可能导致超重/肥胖和慢性炎症的流行,这预示着慢性退行性衰老疾病的风险。
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引用次数: 0
Examining Associations Between Smoking Patterns and Employment Status Among a Nationally Representative Sample of U.S. Adults 在美国成年人的全国代表性样本中研究吸烟模式与就业状况之间的关系
Pub Date : 2025-06-10 DOI: 10.1016/j.focus.2025.100376
Mirsada Serdarevic PhD , Aro N. Choi MS , David Gimeno Ruiz de Porras LPsy, MS, PhD , Tracey E. Barnett PhD

Introduction

Smoking is a leading preventable cause of death, with higher prevalence in certain occupations. Given the evolved work environment after COVID-19 and shifting tobacco use patterns, this study examines recent data to assess the associations between smoking status, employment status, and industry.

Methods

The authors analyzed data from the 2023 National Health Interview Survey. Participants were aged ≥18 years, and their employment status was classified as employed or unemployed on the basis of the prior week’s work; smoking status was classified as current, former, or never. The prevalence of employment and smoking was calculated. Weighted multinomial logistic regression was used to assess the associations between smoking status, employment status, and industry.

Results

Among the 26,442 adults (50.8% male, 63.6% non-Hispanic Whites, mean age of 49.3 years, 69.7% employed), 11.0% were current smokers, 23.4% were former smokers, and 65.6% were never smokers. Current smoking was highest in wholesale trade (20.5%), information (16.9%), and mining (15.9%) industries. After adjustment, unemployed individuals, particularly those unable to work owing to health reasons, had 93% higher odds of being current smokers (AOR=1.93; 95% CI=1.64, 2.28) and 35% higher odds of being former smokers (AOR=1.35; 95% CI=1.16, 1.58) than those who were employed.

Conclusions

This study highlights the current relationship between employment status, industry, and smoking behaviors in the U.S. Current smoking rates were highest in specific industries, underscoring the need for targeted interventions in these occupational settings. Tailored smoking cessation programs for high-risk industries and unemployed individuals, particularly those unable to work owing to health issues, are crucial. Public health policies should address the unique needs of both employed and unemployed populations to reduce smoking-related health disparities.
吸烟是可预防的主要死亡原因,在某些职业中患病率较高。鉴于2019冠状病毒病后工作环境的演变和烟草使用模式的转变,本研究审查了最近的数据,以评估吸烟状况、就业状况和行业之间的关系。方法分析2023年全国健康访谈调查数据。参与者年龄≥18岁,就业状态根据前一周的工作情况分为有工作和失业;吸烟状况分为现在吸烟、曾经吸烟和从不吸烟。计算了就业和吸烟的流行率。使用加权多项逻辑回归来评估吸烟状况、就业状况和行业之间的关系。结果26,442名成人(男性50.8%,非西班牙裔白人63.6%,平均年龄49.3岁,69.7%有工作)中,11.0%为吸烟者,23.4%为戒烟者,65.6%为从不吸烟者。目前吸烟人数最多的行业是批发贸易(20.5%)、信息(16.9%)和采矿业(15.9%)。调整后,失业人员,特别是那些因健康原因无法工作的人,成为当前吸烟者的几率高出93% (AOR=1.93;95% CI=1.64, 2.28),前吸烟者的几率高出35% (AOR=1.35;95% CI=1.16, 1.58)。结论:本研究强调了当前美国就业状况、行业和吸烟行为之间的关系。目前,特定行业的吸烟率最高,强调了对这些职业环境进行针对性干预的必要性。为高风险行业和失业者量身定制的戒烟计划至关重要,尤其是那些因健康问题无法工作的人。公共卫生政策应解决就业人口和失业人口的独特需求,以减少与吸烟有关的健康差距。
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引用次数: 0
Prediabetes Awareness Barriers and Enablers: National Health and Nutrition Examination Survey 2011–2020 糖尿病前期认知障碍与促进因素:2011-2020年全国健康与营养调查
Pub Date : 2025-06-06 DOI: 10.1016/j.focus.2025.100378
Li Wang PhD , Xingran Weng DrPH , Jennifer L. Kraschnewski MD, MPH , Ariana R. Pichardo-Lowden MD, MEd, MS

Introduction

Prediabetes is prevalent and commonly progresses to diabetes when unaddressed. Prediabetes progression is preventable, yet prediabetes unawareness jeopardizes timely intervention. This study examines barriers and enablers of prediabetes awareness, and describes its influence on diet and physical activity.

Methods

We used the United States National Health and Nutrition Examination Survey 2011-2020 data to identify participants with prediabetes. Weighted logistic regression identified factors associated with prediabetes awareness. Weighted logistic and linear regression tested the effects of prediabetes awareness on lifestyle choices such as sugar, carbohydrate and calorie consumption, and physical activity.

Results

Of the 2,749 adult participants identified as having prediabetes, 84% were unaware of their condition. Having had a glucose testing in the previous three years before participating in the survey was the strongest independent contributor of prediabetes awareness (AOR: 3.97, 95% CI: 2.76-5.71, P<0.0001). Prediabetes awareness was associated with weight loss intent (AOR: 1.63, 95% CI: 1.13-2.33, p<0.01), but not with healthy lifestyle choices. Healthcare professionals’ advice was associated with increased exercise (AOR: 1.75, 95% CI: 1.31-2.33, p<0.01), however, not with a change in diet.

Conclusions

Most participants were unaware of their prediabetes condition, regardless of social determinants of health and demographic factors. This suggests the need to promote prediabetes awareness across populations. Proactively evaluating and discussing results may help narrow the unawareness chasm. Lifestyle choices not being associated with prediabetes awareness suggests that mere awareness and medical advice are not enough for patients to embrace healthy behaviors.
前驱糖尿病很普遍,如果不加以治疗,通常会发展为糖尿病。糖尿病前期的进展是可以预防的,但对糖尿病前期的不了解会危及及时干预。本研究探讨了糖尿病前期意识的障碍和促进因素,并描述了其对饮食和身体活动的影响。方法:我们使用2011-2020年美国国家健康与营养调查数据来识别患有前驱糖尿病的参与者。加权逻辑回归确定了与糖尿病前期意识相关的因素。加权逻辑和线性回归测试了糖尿病前期意识对生活方式选择的影响,如糖、碳水化合物和卡路里的消耗,以及身体活动。结果在2749名被确定患有前驱糖尿病的成年参与者中,84%的人不知道自己的病情。在参加调查前的前三年进行过葡萄糖检测是糖尿病前期意识的最大独立贡献者(AOR: 3.97, 95% CI: 2.76-5.71, P<0.0001)。糖尿病前期意识与减肥意图相关(AOR: 1.63, 95% CI: 1.13-2.33, p<0.01),但与健康的生活方式选择无关。医疗保健专业人员的建议与增加锻炼相关(AOR: 1.75, 95% CI: 1.31-2.33, p<0.01),但与饮食改变无关。结论:大多数参与者不知道自己的前驱糖尿病状况,不考虑健康的社会决定因素和人口因素。这表明需要在人群中提高对糖尿病前期的认识。主动评估和讨论结果可能有助于缩小无意识的鸿沟。生活方式的选择与糖尿病前期意识无关,这表明仅仅意识和医疗建议不足以让患者接受健康的行为。
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引用次数: 0
Editorial Board and Journal Information 编辑委员会和期刊信息
Pub Date : 2025-06-01 DOI: 10.1016/S2773-0654(25)00057-4
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引用次数: 0
Do Communities Implementing the Communities That HEAL Intervention Have Significantly Lower Rates of High-Risk Opioid Prescribing and Dispensing? 实施HEAL干预的社区是否显著降低了高风险阿片类药物的处方和配发率?
Pub Date : 2025-05-26 DOI: 10.1016/j.focus.2025.100371
Frances R. Levin MD , Douglas R. Oyler PharmD , Denise C. Babineau PhD , Jennifer Villani PhD , Redonna K. Chandler PhD , Patricia R. Freeman PhD , Daniel P. Alford MD, MPH , Naleef Fareed PhD , Nicole Mack MS , Trang Q. Nguyen MD, DrPh , Daniel M. Walker PhD , Joella Adams PhD , Trevor J. Baker MS , Donna Beers MSN, RN-BC , Shoshana N. Benjamin MPH , Jennifer Bhuiyan PharmD , Derek Blevins MD , James L. David MS , Netrali Dalvi MPH , Lauren D’Costa BS , Nabila El-Bassel PhD
<div><h3>Introduction</h3><div>Prescription opioids can contribute to risk for opioid use disorder and overdoses. Improving prescription opioid safety is a critical component in reducing opioid risks. This report aims to determine whether communities randomized to the Communities That HEAL (CTH) intervention have significantly different rates of prescription opioid safety measures.</div></div><div><h3>Study Design</h3><div>A multisite, 2-arm, community-level, cluster randomized, unblinded, wait-list controlled comparison trial designed to assess the effectiveness of the CTH intervention in reducing opioid-related overdose deaths among community residents 18 years of age or older (adults).</div></div><div><h3>Setting/Participants</h3><div>Sixty-seven (67) communities in Kentucky, Massachusetts, New York, and Ohio. “Participants” were communities in this study. Intervention: The Communities That Heal intervention consists of multiple dimensions: a coalition-driven community engagement process to select and support implementation of Evidence Based Practices; the Opioid-overdose Reduction Continuum of Care Approach, a compendium of Evidence Based Practices and technical assistance resources organized under overdose education and naloxone distribution, medication for Opioid Use Disorder, and prescription[DB1] opioid safety menus; and communication campaigns intended to reduce Opioid Use Disorder stigma and raise awareness and demand for naloxone and medication for Opioid Use Disorder [DB1] I pulled the intervention language from the body of the manuscript. Journal guidelines aske for no abbreviations in Abstract...so that is why everything is spelled out.</div></div><div><h3>Main Outcome(s) and Measure(s)</h3><div>The main outcome was the number of adults with new incident high-risk opioid prescribing episodes after at least a 45-day washout. Other outcomes included the number of opioid-naïve adults with new opioid prescriptions limited to a 7-day supply, number of adults who received opioid prescriptions from multiple prescribers or pharmacies, and number of locations providing drug take-back services. Outcomes were assessed from July 2021-June 2022.</div></div><div><h3>Results</h3><div>There was no statistically significant difference in the adjusted rates for new incident high-risk opioid prescribing per 100,000 adults during the comparison period between intervention (1094.48 (95% CI: [1063.15, 1126.74])) and wait-list control communities (1121.90 (95% CI: [1079.62, 1165.84])). The adjusted relative rate comparing intervention to wait-list control communities was 0.98 (95% CI: [0.93, 1.02]; p-value=0.296). Similarly, there were no statistically significant differences between intervention and wait-list control communities for the other outcomes.</div></div><div><h3>Conclusions and Relevance</h3><div>Although no statistically significant differences were found in prescription opioid safety measures between study arms, improvement in these measures
处方阿片类药物可增加阿片类药物使用障碍和过量的风险。改善处方阿片类药物的安全性是减少阿片类药物风险的关键组成部分。本报告旨在确定随机分配到社区康复(CTH)干预的社区是否具有显着不同的处方阿片类药物安全措施率。研究设计:一项多地点、2组、社区水平、聚类随机、非盲、等候名单对照比较试验,旨在评估CTH干预在减少18岁及以上社区居民(成人)阿片类药物相关过量死亡方面的有效性。背景/参与者肯塔基州、马萨诸塞州、纽约州和俄亥俄州的67个社区。“参与者”是本研究中的社区。干预:“治愈社区”干预包括多个方面:联盟驱动的社区参与过程,以选择和支持实施循证实践;阿片类药物过量减少连续护理方法,根据过量教育和纳洛酮分发,阿片类药物使用障碍药物和处方[DB1]阿片类药物安全菜单组织的循证实践和技术援助资源纲要;以及旨在减少阿片类药物使用障碍耻辱感和提高对纳洛酮和阿片类药物使用障碍药物的认识和需求的交流活动[DB1]我从手稿正文中删除了干预语言。期刊指南要求在摘要中不使用缩写。这就是为什么每件事都要说清楚。主要结局和测量方法主要结局是在至少45天的洗脱期后出现新发高危阿片类药物处方发作的成年人数量。其他结果包括opioid-naïve成年人的新阿片类药物处方限于7天供应,从多个处方者或药房获得阿片类药物处方的成年人数量,以及提供药物回收服务的地点数量。结果评估时间为2021年7月至2022年6月。结果干预组(1094.48 (95% CI:[1063.15, 1126.74])与等候名单对照组(1121.90 (95% CI:[1079.62, 1165.84])在比较期间每10万成人新发高危阿片类药物处方调整率差异无统计学意义。干预组与等候名单对照组的调整相对率为0.98 (95% CI: [0.93, 1.02]; p值=0.296)。同样,在其他结果方面,干预组与等候名单控制组之间也没有统计学上的显著差异。结论和相关性虽然在两个研究组之间的处方阿片类药物安全措施没有发现统计学上的显著差异,但在两个研究组的比较期间,这些措施的改善表明,可能存在试验之外的事件,例如已出版的经修订的疾病控制和预防中心开具阿片类药物的临床实践指南,这可能影响了研究结果。
{"title":"Do Communities Implementing the Communities That HEAL Intervention Have Significantly Lower Rates of High-Risk Opioid Prescribing and Dispensing?","authors":"Frances R. Levin MD ,&nbsp;Douglas R. Oyler PharmD ,&nbsp;Denise C. Babineau PhD ,&nbsp;Jennifer Villani PhD ,&nbsp;Redonna K. Chandler PhD ,&nbsp;Patricia R. Freeman PhD ,&nbsp;Daniel P. Alford MD, MPH ,&nbsp;Naleef Fareed PhD ,&nbsp;Nicole Mack MS ,&nbsp;Trang Q. Nguyen MD, DrPh ,&nbsp;Daniel M. Walker PhD ,&nbsp;Joella Adams PhD ,&nbsp;Trevor J. Baker MS ,&nbsp;Donna Beers MSN, RN-BC ,&nbsp;Shoshana N. Benjamin MPH ,&nbsp;Jennifer Bhuiyan PharmD ,&nbsp;Derek Blevins MD ,&nbsp;James L. David MS ,&nbsp;Netrali Dalvi MPH ,&nbsp;Lauren D’Costa BS ,&nbsp;Nabila El-Bassel PhD","doi":"10.1016/j.focus.2025.100371","DOIUrl":"10.1016/j.focus.2025.100371","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Prescription opioids can contribute to risk for opioid use disorder and overdoses. Improving prescription opioid safety is a critical component in reducing opioid risks. This report aims to determine whether communities randomized to the Communities That HEAL (CTH) intervention have significantly different rates of prescription opioid safety measures.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Study Design&lt;/h3&gt;&lt;div&gt;A multisite, 2-arm, community-level, cluster randomized, unblinded, wait-list controlled comparison trial designed to assess the effectiveness of the CTH intervention in reducing opioid-related overdose deaths among community residents 18 years of age or older (adults).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Setting/Participants&lt;/h3&gt;&lt;div&gt;Sixty-seven (67) communities in Kentucky, Massachusetts, New York, and Ohio. “Participants” were communities in this study. Intervention: The Communities That Heal intervention consists of multiple dimensions: a coalition-driven community engagement process to select and support implementation of Evidence Based Practices; the Opioid-overdose Reduction Continuum of Care Approach, a compendium of Evidence Based Practices and technical assistance resources organized under overdose education and naloxone distribution, medication for Opioid Use Disorder, and prescription[DB1] opioid safety menus; and communication campaigns intended to reduce Opioid Use Disorder stigma and raise awareness and demand for naloxone and medication for Opioid Use Disorder [DB1] I pulled the intervention language from the body of the manuscript. Journal guidelines aske for no abbreviations in Abstract...so that is why everything is spelled out.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Main Outcome(s) and Measure(s)&lt;/h3&gt;&lt;div&gt;The main outcome was the number of adults with new incident high-risk opioid prescribing episodes after at least a 45-day washout. Other outcomes included the number of opioid-naïve adults with new opioid prescriptions limited to a 7-day supply, number of adults who received opioid prescriptions from multiple prescribers or pharmacies, and number of locations providing drug take-back services. Outcomes were assessed from July 2021-June 2022.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;There was no statistically significant difference in the adjusted rates for new incident high-risk opioid prescribing per 100,000 adults during the comparison period between intervention (1094.48 (95% CI: [1063.15, 1126.74])) and wait-list control communities (1121.90 (95% CI: [1079.62, 1165.84])). The adjusted relative rate comparing intervention to wait-list control communities was 0.98 (95% CI: [0.93, 1.02]; p-value=0.296). Similarly, there were no statistically significant differences between intervention and wait-list control communities for the other outcomes.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions and Relevance&lt;/h3&gt;&lt;div&gt;Although no statistically significant differences were found in prescription opioid safety measures between study arms, improvement in these measures ","PeriodicalId":72142,"journal":{"name":"AJPM focus","volume":"4 6","pages":"Article 100371"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145050064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Correlates of Firearm Screening and Counseling in Primary Care in Southeast Michigan 密歇根州东南部初级保健中枪支筛查和咨询的患病率及其相关因素
Pub Date : 2025-05-23 DOI: 10.1016/j.focus.2025.100370
Joseph B. Ladines-Lim MD, PhD , Magdalena Hecht MD , Caleb Arthur MD , Autumn Pu MD , Melissa Ross MD , Kayla Secrest MD , Aaron Sifuentes MD , Justin Litzner BS , Jennifer Stojan MD, MHPE , Michelle Degli Esposti PhD , Jennifer Meddings MD, MSc

Introduction

The American College of Physicians recommends firearm screening and safety counseling for high-risk patients, although frequency of practice is unclear. The authors evaluated the prevalence and correlates of firearm screening and counseling during health maintenance exams.

Methods

The authors performed a cross-sectional analysis of all health maintenance exams for patients aged ≥18 years at an academic center in Southeast Michigan from September 2021 to February 2022. Primary outcomes included documentation of attempted firearm screening and counseling after positive screens. Multinomial logistic regression models estimated the associations between primary outcomes and patient and clinician characteristics using multilevel modeling to account for interclinic variability.

Results

In 27,686 health maintenance exams across 17 clinic sites, attempted screening was documented in 99.8% of visits, principally through routine questionnaires, with positive, negative, or no responses in 15.2%, 48.0%, and 36.8%, respectively. One outlier clinic site documented attempted screening in only 0.9% of health maintenance exams and was excluded. Counseling occurred in 1.1% of positive screens; clinic sites accounted for 36.3% of variability. Counseling was less likely for females (AOR=0.65; 95% CI=0.51, 0.82), patients aged ≥65 years (AOR=0.31; 95% CI=0.21, 0.47), and Asian patients (AOR=0.31; 95% CI=0.16, 0.61) and more likely for internal medicine–pediatrics/family medicine clinicians than internal medicine clinicians (AOR=4.42; 95% CI=1.99, 9.82).

Conclusions

Clinicians documented attempted firearm screening in nearly all health maintenance exams but seldom counseling, which varied across sites and was linked to patient sociodemographic characteristics and clinician specialty as opposed to high-risk clinical features such as psychiatric disorder. Findings suggest that training and quality improvement efforts are needed to ensure appropriate risk-based counseling.
美国医师学会建议对高危患者进行枪支筛查和安全咨询,尽管实践的频率尚不清楚。作者评估了健康维护检查期间枪支筛查和咨询的流行程度及其相关性。方法作者对2021年9月至2022年2月在密歇根州东南部某学术中心进行的≥18岁患者的所有健康维持检查进行了横断面分析。主要结果包括试图进行枪支筛查的记录和筛查阳性后的咨询。多项逻辑回归模型估计了主要结果与患者和临床医生特征之间的关联,使用多水平建模来解释诊所间的可变性。结果在17个诊所进行的27686项健康维护检查中,99.8%的人试图进行筛查,主要是通过常规问卷,其中15.2%的人回答阳性,48.0%的人回答阴性,36.8%的人没有回答。一个异常的诊所仅记录了0.9%的健康维护检查的筛查尝试,并被排除在外。筛查阳性的人中有1.1%进行了咨询;临床地点占变异的36.3%。女性(AOR=0.65; 95% CI=0.51, 0.82)、年龄≥65岁的患者(AOR=0.31; 95% CI=0.21, 0.47)和亚洲患者(AOR=0.31; 95% CI=0.16, 0.61)进行咨询的可能性较小,内科-儿科/家庭医学临床医生比内科临床医生更有可能进行咨询(AOR=4.42; 95% CI=1.99, 9.82)。结论:临床医生在几乎所有的健康维护检查中都记录了试图进行枪支筛查,但很少进行咨询,这在不同的地点有所不同,与患者的社会人口学特征和临床医生的专业有关,而不是与精神疾病等高风险临床特征有关。研究结果表明,需要培训和质量改进工作,以确保适当的基于风险的咨询。
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引用次数: 0
Nutritional Educational Intervention in Users With Psychiatric Disorders Living in Supported Housing: A Pilot Study 营养教育干预生活在支援住房的精神障碍使用者:一项试点研究
Pub Date : 2025-05-16 DOI: 10.1016/j.focus.2025.100368
Giulia Picardo MD , Clara Donnoli RN, MSN , Maria Rosaria Barbera MSc , Marina Agostini MSc , Giuseppe Ducci MD , Giuseppe Liotta PhD

Introduction

The pilot data analysis assessed the weight and eating habits of users in Supported Housing (SH) across six Rome districts, verifying the feasibility of a nutritional education intervention.

Methods

The study team conducted a quantitative, quasi-experimental study. The cohort consisted of 92 users living in 57 houses, categorized by age, sex, and diagnosis. The intervention carried out between October 2021 and January 2022 consisted of 2 phases, an educational session on the food pyramid and national dietary guidelines for staff assisting users and an education intervention to promote healthier lifestyle choices to the users.

Results

Results reported an average BMI of 28 kg/m2 (SD = ±5.74) categorizing users as belonging in average to the overweight BMI class. Adherence to the Mediterranean diet based on the Del Balzo and Savastano1 questionnaire was overall scarce (90.1%). The educational intervention positively impacted 90.3% of users who demonstrated an increase in consumption of fruit and vegetables and a decrease in consumption of fried food and soft drinks. A weight decrease was experienced by 43.4% (13/30) of the cohort. Average weight loss, in the group who lost weight, was 7.6kg (SD = ±6.93).

Conclusions

The study suggests the feasibility and potential impact of public health initiatives addressing obesity in the population with psychiatric disorders.
试点数据分析评估了罗马六个地区支持住房(SH)用户的体重和饮食习惯,验证了营养教育干预的可行性。方法课题组进行定量、准实验研究。该队列包括居住在57所房屋中的92名用户,按年龄、性别和诊断进行分类。在2021年10月至2022年1月期间进行的干预包括两个阶段:为协助用户的工作人员举办的关于食物金字塔和国家饮食指南的教育会议,以及向用户推广更健康的生活方式选择的教育干预。结果报告的平均BMI为28 kg/m2 (SD =±5.74),将使用者归类为平均超重BMI类别。根据Del Balzo和Savastano1问卷调查,坚持地中海饮食的人总体上很少(90.1%)。教育干预对90.3%的用户产生了积极影响,他们表现出水果和蔬菜的消费量增加,油炸食品和软饮料的消费量减少。43.4%(13/30)的队列患者体重减轻。减肥组平均体重减轻7.6kg (SD =±6.93)。结论本研究提示了在精神疾病人群中采取公共卫生措施解决肥胖问题的可行性和潜在影响。
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引用次数: 0
Pediatric Produce Prescription Program Grounded in Community Connection Improves Fruit Intake in Hawaiʻi 基于社区联系的儿科农产品处方计划改善了夏威夷的水果摄入量
Pub Date : 2025-05-09 DOI: 10.1016/j.focus.2025.100365
Monica K. Esquivel PhD, RDN , Cherese Shelton BS , Alicia Higa BS , Hyeong Jun Ahn PhD , May Okhiro MD, MS

Introduction

In Hawai‘i, 50% of Native Hawaiian and Pacific Islander children live in a household experiencing food insecurity. Individuals from food insecure households experience increased risk for chronic health conditions that may be alleviated with healthy food. Wellness for Native Hawaiian and Pacific Islander populations can be achieved through the Pilinahā framework, comprising connection to self; community; past, present, and future; and land. The Keiki (child) Produce Prescription Program was designed to address the Pilinahā framework through a 6-month intervention that provided pediatric participants with vouchers totaling $50 per month to exchange for local, fresh fruits and vegetables from the farmers market along with nutrition education kits.

Methods

The community-designed intervention connected pediatric patients from a large federally qualified health center with the community farmers’ market. Eligibility consisted of children aged 2–17 years who screened positive for a nutrition-related chronic disease or food insecurity. Baseline survey and 6-month data collected included sociodemographic data, household food security, and fruit and vegetable consumption. Monthly voucher redemption was tracked.

Results

One hundred and twenty-one participants enrolled, 90 participants redeemed vouchers for 6 months, and 75 (62%) completed 6-month survey data. Participants redeemed $210 (70%) in vouchers on average. Children’s fruit consumption increased by 1.0 cups per day (p=0.014), whereas parent fruit consumption increased by 1.2 cups per day (p=0.0001). No changes to household food security or total fruit and vegetable consumption were observed.

Conclusions

The Keiki Produce Prescription Program improved fruit intake among households with children. High levels of program participation and completion reinforce the importance of community-engaged approaches to program development. Rigorous testing through RCTs and increasing engagement with nutrition education are recommended for future studies.
在夏威夷,50%的夏威夷原住民和太平洋岛民儿童生活在粮食不安全的家庭中。来自粮食不安全家庭的个人患慢性疾病的风险增加,而这些疾病可以通过健康食品得到缓解。夏威夷原住民和太平洋岛民的健康可以通过pilinahha框架实现,包括与自我的联系;社区;过去、现在和未来;和土地。Keiki(儿童)农产品处方项目旨在通过为期6个月的干预来解决pilinahha框架问题,该项目每月向儿童参与者提供总额为50美元的代金券,用于从农贸市场购买当地新鲜水果和蔬菜以及营养教育工具包。方法采用社区设计的干预措施,将来自大型联邦合格医疗中心的儿科患者与社区农贸市场联系起来。资格包括2-17岁的儿童,他们在营养相关慢性疾病或粮食不安全筛查中呈阳性。基线调查和收集的6个月数据包括社会人口统计数据、家庭粮食安全以及水果和蔬菜消费。跟踪每月代金券的兑换情况。结果121名参与者入组,90名参与者兑换了6个月的代金券,75名参与者(62%)完成了6个月的调查数据。参与者平均兑换了210美元(70%)的代金券。儿童每天的水果消费量增加了1.0杯(p=0.014),而父母每天的水果消费量增加了1.2杯(p=0.0001)。没有观察到家庭食品安全或水果和蔬菜消费总量的变化。结论Keiki农产品处方项目改善了有孩子家庭的水果摄入量。高水平的项目参与和完成强化了社区参与项目发展的重要性。建议在未来的研究中通过随机对照试验进行严格的测试,并加强营养教育。
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引用次数: 0
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