{"title":"Geographical access to breast reconstruction: does location matter?","authors":"C. Kaoutzanis, Alec McCranie","doi":"10.21037/abs-22-61","DOIUrl":"https://doi.org/10.21037/abs-22-61","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48285898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Partial breast irradiation (PBI) has been increasingly accepted as a suitable component of breast conservation in the management of patients with early stage breast cancer, however the majority of existing studies have focused on the use of adjuvant or intra-operative techniques. Several early stage studies have more recently shown that PBI can be safely used in the pre-operative setting. Early data show similar local control without evidence of increased toxicity or worsening cosmesis, as compared to postoperative PBI or standard whole breast irradiation. While long term data are still maturing, pre-operative accelerated PBI (PAPBI) offers a number of possible clinical advantages including reducing the treatment field and increasing the number of patients eligible for PBI, identifying biomarkers of response to radiation, and improving the rates of breast conservation and treatment compliance. This review discusses key concepts and controversies surrounding PBI as it has increasingly been adopted in the US, Canada, and Europe, and introduces the concepts and early studies of PAPBI. In addition, we summarize ongoing clinical trials investigating PAPBI, review clinical benefits and challenges associated with PAPBI versus postoperative PBI, and discuss ongoing limitations as well as next generation technologies important to the implementation of PAPBI in the management of patients with early-stage localized breast cancer.
{"title":"Pre-operative partial breast irradiation: revolutionizing radiation treatment for women with early stage breast cancer.","authors":"Yun R Li, Parul N Barry","doi":"10.21037/abs-20-133","DOIUrl":"https://doi.org/10.21037/abs-20-133","url":null,"abstract":"<p><p>Partial breast irradiation (PBI) has been increasingly accepted as a suitable component of breast conservation in the management of patients with early stage breast cancer, however the majority of existing studies have focused on the use of adjuvant or intra-operative techniques. Several early stage studies have more recently shown that PBI can be safely used in the pre-operative setting. Early data show similar local control without evidence of increased toxicity or worsening cosmesis, as compared to postoperative PBI or standard whole breast irradiation. While long term data are still maturing, pre-operative accelerated PBI (PAPBI) offers a number of possible clinical advantages including reducing the treatment field and increasing the number of patients eligible for PBI, identifying biomarkers of response to radiation, and improving the rates of breast conservation and treatment compliance. This review discusses key concepts and controversies surrounding PBI as it has increasingly been adopted in the US, Canada, and Europe, and introduces the concepts and early studies of PAPBI. In addition, we summarize ongoing clinical trials investigating PAPBI, review clinical benefits and challenges associated with PAPBI versus postoperative PBI, and discuss ongoing limitations as well as next generation technologies important to the implementation of PAPBI in the management of patients with early-stage localized breast cancer.</p>","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":"6 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/17/fe/nihms-1861162.PMC9837822.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10534471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast conserving surgery revisited: a narrative review","authors":"U. Jain, A. Kothari, S. Joshi, Y. Masannat","doi":"10.21037/abs-21-98","DOIUrl":"https://doi.org/10.21037/abs-21-98","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46431876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rancati, C. Angrigiani, J. Dorr, M. Cortiñas, A. Rancati, Juan Acquaviva, Marcelo Bou
{"title":"Immediate nipple areolar complex reconstruction over latissimus dorsi skin paddle flap in bilateral periareolar mastectomy & reconstruction","authors":"A. Rancati, C. Angrigiani, J. Dorr, M. Cortiñas, A. Rancati, Juan Acquaviva, Marcelo Bou","doi":"10.21037/abs-21-144","DOIUrl":"https://doi.org/10.21037/abs-21-144","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48065277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel pathophysiology of gestational gigantomastia in the setting of COVID-19 infection","authors":"Ann-Kristin Friedrich","doi":"10.21037/abs-22-17","DOIUrl":"https://doi.org/10.21037/abs-22-17","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49622488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Max L. Silverstein, Robert D. Nesbit, M. Collins, T. Willson
{"title":"The impact of geographical access challenges on outcomes of postmastectomy breast reconstruction","authors":"Max L. Silverstein, Robert D. Nesbit, M. Collins, T. Willson","doi":"10.21037/abs-22-32","DOIUrl":"https://doi.org/10.21037/abs-22-32","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48375584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Breast cancer incidence has been steadily increasing manly in high income countries as is life expectancy. The majority of newly diagnosed breast cancer cases will occur in post-menopausal women with an increasing in the older age group. As in younger women oncoplastic surgery and post mastectomy breast reconstruction should also be viable options, when needed, in older women. However, this is not the case in most centres and chronological age alone seems to be a barrier to these surgical alternatives. We evaluated the most relevant and recently published literature on the topic to analyse the available evidence in favour and against the use of oncoplastic breast surgery and post mastectomy breast reconstruction in this age group. Older women are not significantly represented in randomized clinical trials. There is minimal published evidence on oncoplastic breast surgery. Regarding post mastectomy breast reconstruction, although there are more publications, most studies are retrospective, present an evident selection bias and are very heterogeneous. Regarding oncoplastic surgery and post mastectomy breast reconstruction, there is no evidence that, compared to younger age groups, higher rates of complications should lead to the denial of these choices to older women, especially in the absence of associated comorbidities. Patient reported outcomes are not sufficiently explored in older women but, based on the limited available evidence, older women report higher rates of satisfaction when compared to younger women regarding oncoplastic surgery and post mastectomy breast reconstruction. Decisions in older women proposed for breast surgery and in need of oncoplastic breast surgery or post mastectomy breast reconstruction should always integrate, patients preference, a geriatric assessment and a life expectancy estimation. In case of unfavourable geriatric assessment and low estimation of life expectancy, a higher complication rate should be anticipated. It is not likely that randomized controlled trials will happen in this age group not only due to ethical concerns (as oncoplastic surgery and post mastectomy reconstruction are already standard of care in other age groups) but also to the difficulties in obtaining meaningful numbers. However, well designed prospective cohorts can be a valuable alternative to the scarce available retrospective evidence.
{"title":"Oncoplastic surgery and breast reconstruction in the elderly: an unsolved conundrum","authors":"C. Mavioso, C. Pereira, M. Cardoso","doi":"10.21037/abs-21-137","DOIUrl":"https://doi.org/10.21037/abs-21-137","url":null,"abstract":": Breast cancer incidence has been steadily increasing manly in high income countries as is life expectancy. The majority of newly diagnosed breast cancer cases will occur in post-menopausal women with an increasing in the older age group. As in younger women oncoplastic surgery and post mastectomy breast reconstruction should also be viable options, when needed, in older women. However, this is not the case in most centres and chronological age alone seems to be a barrier to these surgical alternatives. We evaluated the most relevant and recently published literature on the topic to analyse the available evidence in favour and against the use of oncoplastic breast surgery and post mastectomy breast reconstruction in this age group. Older women are not significantly represented in randomized clinical trials. There is minimal published evidence on oncoplastic breast surgery. Regarding post mastectomy breast reconstruction, although there are more publications, most studies are retrospective, present an evident selection bias and are very heterogeneous. Regarding oncoplastic surgery and post mastectomy breast reconstruction, there is no evidence that, compared to younger age groups, higher rates of complications should lead to the denial of these choices to older women, especially in the absence of associated comorbidities. Patient reported outcomes are not sufficiently explored in older women but, based on the limited available evidence, older women report higher rates of satisfaction when compared to younger women regarding oncoplastic surgery and post mastectomy breast reconstruction. Decisions in older women proposed for breast surgery and in need of oncoplastic breast surgery or post mastectomy breast reconstruction should always integrate, patients preference, a geriatric assessment and a life expectancy estimation. In case of unfavourable geriatric assessment and low estimation of life expectancy, a higher complication rate should be anticipated. It is not likely that randomized controlled trials will happen in this age group not only due to ethical concerns (as oncoplastic surgery and post mastectomy reconstruction are already standard of care in other age groups) but also to the difficulties in obtaining meaningful numbers. However, well designed prospective cohorts can be a valuable alternative to the scarce available retrospective evidence.","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43088975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Ozcan, Kanwal Merchant, J. Goldberg, Zachariah Burns, S. Sahoo, Lindsay Compton, Jody C Hayes, B. Dogan
{"title":"Can imaging findings predict the outcome of idiopathic granulomatous mastitis?","authors":"B. Ozcan, Kanwal Merchant, J. Goldberg, Zachariah Burns, S. Sahoo, Lindsay Compton, Jody C Hayes, B. Dogan","doi":"10.21037/abs-22-23","DOIUrl":"https://doi.org/10.21037/abs-22-23","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined localization technique with radio-guided occult lesion localization and Magseed for breast-conserving surgery for non-palpable multifocal breast cancer: a case report","authors":"Ray Ka‐wai Hung, Ho wai Ip, Violet Yee Kei Tsoi","doi":"10.21037/abs-22-20","DOIUrl":"https://doi.org/10.21037/abs-22-20","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43413876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in molecular medicine for breast cancer practice: a narrative review","authors":"R. Velaga, M. Toi","doi":"10.21037/abs-21-64","DOIUrl":"https://doi.org/10.21037/abs-21-64","url":null,"abstract":"","PeriodicalId":72212,"journal":{"name":"Annals of breast surgery : an open access journal to bridge breast surgeons across the world","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42588684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号