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[Diuretic resistance and heart failure: between congestion and kidney injury]. [利尿剂耐药性与心力衰竭:充血与肾损伤之间]。
Pub Date : 2023-09-30 eCollection Date: 2023-07-01 DOI: 10.47487/apcyccv.v1i3.72
Paola Morejón Barragán

Nowadays, heart Failure (HF) is one of the main contributors of cardiovascular morbidity and mortality, this faces us with great challenges. The heart-kidney interaction receives particular attention due to the development of the so-called cardiorenal syndrome (CRS) and the diuretic resistance, latter is a predictor of adverse events in acute HF and is independent of the glomerular filtration rate. Development of diuretic resistance is secondary to multiple causes, so a comprehensive evaluation of all of them is required. In recent years, congestion has become relevant within the pathophysiological mechanism of CRS, as it mutually generates and perpetuates damage in these two organs. Given the importance of congestion, diuretics remain the cornerstone of treatment, although their use is largely empirical due to the limited evidence available. The evidence-based treatment paradigm is elusive in this scenario, so one question remains unanswered: Do the interventions to treat or to prevent the diuretic resistance modify the prognosis in acute HF?

如今,心力衰竭(HF)是心血管疾病发病率和死亡率的主要诱因之一,这给我们带来了巨大的挑战。由于所谓的心肾综合征(CRS)和利尿剂抵抗的发生,心脏与肾脏的相互作用受到特别关注,后者是急性心力衰竭不良事件的预测因素,与肾小球滤过率无关。利尿剂抵抗的发生继发于多种原因,因此需要对所有原因进行综合评估。近年来,充血已成为 CRS 病理生理机制中的一个重要因素,因为它在这两个器官中相互产生并延续损害。鉴于充血的重要性,利尿剂仍然是治疗的基石,尽管由于证据有限,利尿剂的使用在很大程度上是经验性的。在这种情况下,循证治疗模式难以捉摸,因此有一个问题仍然没有答案:治疗或预防利尿剂耐药的干预措施是否会改变急性心房颤动的预后?
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引用次数: 0
[Spatial analysis of hypertension in Peruvian adults, 2022]. [秘鲁成年人高血压的空间分析,2022年]。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.296
Akram Hernández-Vásquez, Brenda Noemí Carrillo Morote, Victoria Del Carmen Azurin Gonzales, Efraín Y Turpo Cayo, Diego Azañedo

Objectives: To perform a spatial analysis of arterial hypertension in the Peruvian adult population to identify geographic patterns with a higher concentration of cases.

Materials and methods: A spatial analysis was conducted using data from the Demographic and Family Health Survey (ENDES) 2022. A sample of 29,422 adults was included, and the global Moran's index and Getis-Ord Gi* analysis were used to evaluate spatial autocorrelation and cluster concentration.

Results: The age-standardized prevalence of arterial hypertension was 19.2%. Clusters with a high concentration of arterial hypertension were observed in departments along the Peruvian coast such as Tumbes, Piura, Lambayeque, La Libertad, Ancash, and Lima, as well as in the northern regions of the Highlands. Clusters were also found in the regions of Loreto and Madre de Dios in the Peruvian jungle.

Conclusions: This study revealed geographic patterns of arterial hypertension in Peru, with a higher concentration of cases along the Peruvian coast and in certain regions of the Highlands and Jungle. These findings highlight the need to develop strategies for the prevention and control of the disease, especially in the areas identified as high-prevalence clusters.

目的:对秘鲁成年人群的动脉高压进行空间分析,以确定病例更集中的地理模式。材料和方法:使用2022年人口和家庭健康调查(ENDES)的数据进行空间分析。纳入29422名成年人的样本,使用全球莫兰指数和Getis Ord-Gi*分析来评估空间自相关和聚类浓度。结果:动脉高压的年龄标准化患病率为19.2%。在秘鲁海岸的图姆斯、皮乌拉、兰巴耶克、拉利伯塔德、安卡什和利马等省以及高地的北部地区,观察到动脉高压高浓度的集群。在秘鲁丛林中的洛雷托和马德雷德迪奥斯地区也发现了集群。结论:这项研究揭示了秘鲁动脉高压的地理模式,秘鲁海岸以及高地和丛林的某些地区的病例更为集中。这些发现突出表明,需要制定预防和控制该疾病的战略,特别是在被确定为高流行率集群的地区。
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引用次数: 0
Cardiac magnetic resonance as a risk re-stratification tool in apical hypertrophic cardiomyopathy. 心脏磁共振作为心尖肥厚型心肌病的风险再分层工具。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.289
Ana María Larriva, Sandra Rosales Uvera, Zuilma Vásquez, Beatriz Fernández, Diego Xavier Chango Azanza

Apical hypertrophic cardiomyopathy (ApHCM) can result in the formation of a left ventricular apical aneurysm and progressive myocardial fibrosis, which is associated with a worse prognosis. We present the case of a 76-year-old man previously diagnosed with ApHCM seven years ago, who has been under clinical follow-up. Serial cardiac magnetic resonance (CMR) imaging was performed in 2013 and 2020 due to suspected apical aneurysm formation based on echocardiographic evaluation. The 2020 CMR imaging revealed an increase in myocardial fibrosis observed through late-gadolinium enhancement images and, for the first time, a small apical aneurysm that was not clearly visualized on two-dimensional echocardiography. The time course leading to the development of an ApHCM aneurysm is not well-defined and may impact the clinical course.

心尖肥厚型心肌病(ApHCM)可导致左心室心尖动脉瘤的形成和进行性心肌纤维化,这与较差的预后有关。我们报告了一名76岁的男性病例,他在七年前被诊断为ApHCM,目前正在接受临床随访。根据超声心动图评估,由于怀疑心尖动脉瘤形成,于2013年和2020年进行了连续心脏磁共振(CMR)成像。2020年CMR成像显示,通过晚期钆增强图像观察到的心肌纤维化增加,并首次在二维超声心动图上显示出一个未清晰显示的小心尖动脉瘤。导致ApHCM动脉瘤发展的时间进程尚不明确,可能会影响临床进程。
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引用次数: 0
[Analysis of cardiac surgeries and operative mortality at the National Cardiovascular Institute during 2022]. 【2022年美国国家心血管研究所心脏手术和手术死亡率分析】。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.287
Gerber Polo-Gutierrez, Harod Anders Silva-Tejada, Franklin Willy Martinez-Ninanqui, Victor Robles-Velarde, Josías Ríos-Ortega

Objective: To describe cardiac surgeries, their approaches, and determine operative mortality according to the type of surgery and the main complications recorded within 30 days postoperatively, performed at the National Cardiovascular Institute of Peru.

Materials and methods: A descriptive study was conducted on all patients over 18 years of age who underwent cardiovascular surgery at the National Cardiovascular Institute "Carlos Alberto Peschiera Carrillo".

Results: During the year 2022, a total of 503 cardiac surgeries were performed. Of the patients undergoing surgery, 63.6% (320) were males. Isolated valvular surgery, primarily aortic or mitral valve replacement, was the most frequent surgical procedure, with 136 surgeries (27.0%). This was followed by myocardial revascularization surgery with 110 procedures (21.9%). Throughout the year, there were 23 deaths, resulting in an overall mortality rate of 4.5%. The mortality rate for elective surgeries was 2.8%, while for emergency surgeries, it was 14.3%. The most common complication was paroxysmal atrial fibrillation (14.0%), followed by surgical site infection with 52 cases (10.3%).

Conclusions: Valvular surgery, whether isolated or combined with other procedures, was the most frequently performed. The obtained mortality rate is considered acceptable for a reference center.

目的:描述心脏手术及其方法,并根据手术类型和术后30天内记录的主要并发症确定手术死亡率,材料和方法:对在国家心血管研究所“Carlos Alberto Peschiera Carrillo”接受心血管手术的所有18岁以上患者进行了描述性研究。结果:2022年,共进行了503次心脏手术。在接受手术的患者中,63.6%(320)为男性。孤立性瓣膜手术,主要是主动脉瓣或二尖瓣置换术,是最常见的手术,共有136例(27.0%)。其次是心肌血运重建手术,共110例(21.9%)。全年共有23例死亡,总死亡率为4.5%。选择性手术的死亡率为2.8%,急诊手术发生率为14.3%,最常见的并发症为阵发性心房颤动(14.0%),其次为手术部位感染52例(10.3%)。所获得的死亡率被认为是参考中心可以接受的。
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引用次数: 0
[Atypical presentation of ruptured aneurysmal right sinus of Valsalva with severe aortic insufficiency]. [瓦尔萨尔瓦动脉瘤性右窦破裂伴严重主动脉瓣关闭不全的非典型表现]。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i1.284.
Miguel Ángel Serrano-Sánchez, Alfredo Sotomayor-Estrada, W Samir Cubas

Aneurysm of the Sinus of Valsalva (ASV) is a rare abnormality and affects less than 0.1% of the general population. We describe the case of a 37-year-old woman with a clinical picture characterized by dyspnea, palpitations, and syncope of 6 years of evolution. The echocardiographic study revealed a right ASV with a sub pulmonary interventricular perforation of 8mm and producing a regurgitant jet into the right ventricle, causing dilatation of the right ventricular outflow tract, pulmonary artery, and severe aortic insufficiency Carpentier DI. The patient underwent successful repair of the defect and interventricular perforation, and valve replacement was not necessary. Timely echocardiographic diagnosis and early surgery are the main predictors that make the difference between an excellent outcome and certain death.

瓦尔萨尔瓦窦瘤(ASV)是一种罕见的异常,影响不到0.1%的普通人群。我们描述了一例37岁的女性,其临床表现为呼吸困难、心悸和晕厥,经过6年的演变。超声心动图研究显示,右ASV的肺下室间穿孔为8mm,并向右心室产生反流,导致右心室流出道、肺动脉扩张和严重主动脉瓣关闭不全Carpentier DI。患者成功修复了缺损和室间穿孔,无需更换瓣膜。及时的超声心动图诊断和早期手术是区分良好结果和一定死亡的主要预测因素。
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引用次数: 0
Presentación atípica de rotura de seno de Valsalva derecho aneurismático con insuficiencia aortica severa 动脉瘤性右Valsalva窦破裂伴严重主动脉功能不全的非典型表现
Pub Date : 2023-06-30 DOI: 10.47487/apcyccv.v4i2.284
Archivos Peruanos de Cardiología, Cirugía Cardiovascular, E. R. Martins, Lima Perú. a Médico residente. b Médico asistente., Miguel Ángel Serrano-Sánchez, Alfredo L Sotomayor-Estrada, Samir Cubas
RESUMEN El aneurisma del seno de Valsalva (ASV) es una anormalidad poco frecuente que afecta a menos del 0,1% de la población en general. Se describe el caso de una mujer de 37 años con un cuadro clínico de 6 años de evolución caracterizado por disnea, palpitaciones y síncope. El estudio ecocardiográfico evidenció ASV derecho con una perforación interventricular subpulmonar de 8 mm que producía un jet de regurgitación hacia el ventrículo derecho que ocasionaba la dilatación del tracto de salida de ventrículo derecho, la arteria pulmonar e insuficiencia aórtica severa Carpentier ID. El paciente se sometió a una reparación exitosa del defecto y de la perforación interventricular, sin necesidad de reemplazo valvular. El diagnóstico ecocardiográfico oportuno y una cirugía precoz, son los principales predictores que suponen la diferencia entre una evolución excelente y una muerte segura.
本文的目的是分析在西班牙和葡萄牙进行的一项研究的结果,该研究的目的是分析在西班牙和葡萄牙进行的一项研究的结果,该研究的目的是分析在西班牙进行的一项研究的结果。本研究的目的是评估一种新的治疗方法,该方法基于一种新的治疗方法,在这种方法中,患者的呼吸困难、心律失常和晕厥是最常见的症状。超声心动图显示右ASV有8毫米的肺下心室穿刺,产生反流流到右心室,导致右心室出口通道扩张,肺动脉和严重的Carpentier ID主动脉功能不全。患者成功修复了缺损和心室穿刺,不需要瓣膜置换。及时的超声心动图诊断和早期手术是预后良好和安全死亡之间的主要预测因素。
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引用次数: 0
[Clinical characteristics and care times in a chest pain unit of the emergency department of an argentine center]. [阿根廷中心急诊科胸痛病房的临床特征和护理时间]。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.293
María Florencia Grande Ratti, Ignacio Martín Bluro, Fiorella Castillo, María Elena Zapiola, Ana Soledad Pedretti, Bernardo Martínez

Objectives: . To report the frequency of precordial pain, describe clinical characteristics, and care times.

Methods: . Retrospective descriptive study that included consultations in the Chest Pain Unit in 2021 in the emergency department of a private hospital in Argentina.

Results: There were 1469 admissions for chest pain, yielding a frequency of 1.09% (95%CI 1.04-1.15). They were 52% men, mean age 62 years (SD ±15); 48% had hypertension and 32% dyslipidemia. The median time to initial ECG was 4.3 min (ICR 2.5-7.5); and 26 min (ICR 14-46) to medical evaluation. A total of 206 (14%) were hospitalized with a median of 3 days, 76% were admitted to a closed unit, 9% required non-invasive ventilation/mechanical ventilaction and in-hospital mortality was 2.9%. Those hospitalized presented shorter delay time to medical attention (p<0.01), and greater performance of complementary studies (p<0.01), with no differences in time to ECG (p=0.22).

Conclusions: Care times were within the stipulated standards, being an important indicator of quality. Nursing was crucial, taking care of the correct triage, ECG on admission, and guaranteeing care until medical evaluation.

目标:。报告心前区疼痛的频率,描述临床特征和护理时间。方法:。回顾性描述性研究,包括2021年在阿根廷一家私立医院急诊科胸痛科的会诊。结果:1469例因胸痛入院,发生率为1.09%(95%CI 1.04-1.15),其中52%为男性,平均年龄62岁(SD±15);48%患有高血压,32%患有血脂异常。初始心电图的中位时间为4.3分钟(ICR 2.5-7.5);26分钟(ICR 14-46)进行医学评估。共有206人(14%)住院,中位数为3天,76%的人入住封闭式病房,9%的患者需要无创通气/机械通气,住院死亡率为2.9%。住院患者延迟就医的时间较短(P结论:护理时间在规定的标准范围内,是质量的一个重要指标。护理至关重要,要注意正确的分诊、入院时的心电图,并保证护理直到医疗评估。
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引用次数: 0
[Case report: ablation of atrial fibrillation in patient with an interatrial septal oclussion device]. [病例报告:应用房间隔闭锁装置消融心房颤动患者]。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.288
Renee Montesinos-Segura, Diego Davila-Flores, Fernando Quevedo-Candela, Mario Cabrera-Saldaña, Pío Zelaya-Castro, Richard Soto-Becerra

Interatrial septal occlusion devices hinder the transseptal approach for atrial fibrillation ablation, making it necessary to have imaging methods that safely guide transseptal puncture, such as intracardiac echocardiography (ICE). We describe the case of a 49-year-old patient with symptomatic paroxysmal atrial fibrillation, refractory to antiarrhythmic drugs, wearing an interatrial septal occlusion device, with a previous unsuccessful ablation attempt. Atrial fibrillation ablation was performed using the Carto V7 3D mapping system, the transseptal puncture was guided by ICE, and the procedure was successful. This case report highlights the importance of multimodality imaging to achieve successful and effective transseptal puncture for atrial fibrillation ablation in patients with interatrial septal occlusion devices.

房间隔封堵装置阻碍了心房颤动消融的经中隔入路,因此有必要采用安全指导经中隔穿刺的成像方法,如心内超声心动图(ICE)。我们描述了一例49岁的有症状的阵发性心房颤动患者,该患者对抗心律失常药物难治,佩戴房间隔封堵装置,之前曾尝试消融失败。使用Carto V7 3D标测系统进行心房颤动消融,在ICE的指导下进行房间隔穿刺,手术成功。本病例报告强调了多模态成像对使用房间隔封堵装置的患者成功有效的房间隔穿刺心房颤动消融的重要性。
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引用次数: 0
[Left atrium remodeling after catheter ablation of atrial fibrillation]. 【心房颤动导管消融术后左心房重构】。
Pub Date : 2023-06-30 eCollection Date: 2023-04-01 DOI: 10.47487/apcyccv.v4i2.280
Diego Xavier Chango Azanza, Cristina Tenorio, Xavier Picón, Jorge Coello, Jessica Robles, Javier Pinos
RESUMEN La fibrilación auricular (FA) es la arritmia cardiaca más frecuente. Su asociación con la aparición de eventos embólicos cardiovasculares y de insuficiencia cardiaca es elevada. Los cambios estructurales y funcionales son parte fundamental del proceso fisiopatológico, dando origen a una miopatía auricular izquierda y a disfunción ventricular izquierda progresiva que modifica el pronóstico de los pacientes. Se presenta el caso de un paciente de 75 años de edad con presencia de FA paroxística sintomática en adecuada clase funcional que es derivado para ablación de venas pulmonares posterior a fracaso de la terapia antiarrítmica. El ecocardiograma inicial mostró una función sistólica biventricular conservada, ligera disfunción diastólica y una aurícula izquierda (AI) con volúmenes normales. Sin embargo, se observó deterioro funcional con un strain en fase reservorio disminuido. Se realizó aislamiento de las venas pulmonares en forma exitosa sin la evidencia de nuevos eventos arrítmicos, además de una mejoría del strain de reservorio de la AI, del strain longitudinal global del ventrículo izquierdo (VI) y del índice de trabajo miocárdico a los tres meses de seguimiento. El paciente ha permanecido asintomático y se encuentra bajo seguimiento clínico. El strain de AI y VI como nuevas técnicas avanzadas de la ecocardiografía son herramientas útiles en la valoración del remodelado reverso de la miopatía auricular y del daño estructural del VI.
心房颤动(AF)是最常见的心律失常。它与心血管栓塞事件和心力衰竭有很高的相关性。结构和功能变化是病理生理过程的基本组成部分,导致左心房肌病和进行性左心室功能障碍,从而改变患者的预后。我们报告了一例75岁的有症状的阵发性房颤患者,该患者在抗心律失常治疗失败后被转诊进行肺静脉消融术。最初的超声心动图显示双心室收缩功能保持,轻度舒张功能障碍,左心房(LA)容积正常。然而,随着储层相应变的降低,观察到功能性左心房损伤。在没有新的心律失常事件证据的情况下,成功地进行了肺静脉隔离,此外,在三个月的随访中,左心室储层应变、左心室(LV)整体纵向应变和心肌功指数有所改善。该患者仍无症状,正在接受临床随访。左心房和左心室应变作为新的先进超声心动图技术,可用于评估心房肌病的反向重构和左心室结构评估。
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引用次数: 0
[Quality of life in patients with idiopathic ventricular arrhythmias treated at the Instituto Nacional Cardiovascular - INCOR]. [在国家心血管研究所(INCOR)接受治疗的特发性室性心律失常患者的生活质量]。
Pub Date : 2023-03-31 eCollection Date: 2023-01-01 DOI: 10.47487/apcyccv.v4i1.279
Richard Soto-Becerra, Ofelia Aráoz-Tarco, Mario Cabrera-Saldaña, Carolina Guevara-Caicedo, Pio Zelaya-Castro, Ricardo Zegarra-Carhuaz

Objective: To describe the quality of life in patients with idiopathic ventricular arrhythmias treated at the Instituto Nacional Cardiovascular INCOR in Lima -Peru.

Materials and methods: . Analytical and cross-sectional study of patients with idiopathic ventricular arrhythmias treated by 3D ablation or antiarrhythmic therapy between July 2017 and December 2019 to whom the SF-36 health questionnaire was applied to assess quality of life related to health.

Results: Fifty-two patients with idiopathic ventricular arrhythmias were included (34 underwent 3D ablation, and 18 underwent antiarrhythmic therapy only). The percentage of recurrence (14.7% vs. 50%, p=0.01) and adverse effects (0% vs. 22.2%, p=0.011) were lower in the 3D ablation group compared to the antiarrhythmic group. The mean standardized scores obtained from the Spanish version of the Health Survey SF-36v2, applied to the 3D ablation and antiarrhythmic groups were 85.1 vs 68.4 (p<0.001), respectively. Were found statistically significant differences in 6 of the eight components that evaluate health-related quality of life: physical function (96.0 vs. 76.0, p<0.001), physical role (93.4 vs. 61.1, p<0.001), general health (74.5 vs. 47.4, p<0.001), vitality (69.9 vs 54.7, p=0.008), emotional role (92.2 vs. 77.8, p=0.006) and mental health (73.8 vs. 60, p<0.001).

Conclusions: Patients with idiopathic ventricular arrhythmias who underwent 3D ablation have a higher mean standardized score for health-related quality of life.

目的描述在秘鲁利马国立心血管研究所(INCOR)接受治疗的特发性室性心律失常患者的生活质量。对2017年7月至2019年12月期间接受三维消融或抗心律失常治疗的特发性室性心律失常患者进行分析和横断面研究,并对其应用SF-36健康问卷评估与健康相关的生活质量:共纳入52例特发性室性心律失常患者(34例接受了三维消融术,18例仅接受了抗心律失常治疗)。与抗心律失常组相比,三维消融组的复发率(14.7% 对 50%,P=0.01)和不良反应率(0% 对 22.2%,P=0.011)更低。三维消融组和抗心律失常组的西班牙版健康调查SF-36v2的平均标准化得分分别为85.1分和68.4分(P结论:接受三维消融术的特发性室性心律失常患者的健康相关生活质量平均标准化得分更高。
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引用次数: 0
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Archivos Peruanos de cardiologia y cirugia cardiovascular
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