Brain & spine最新文献

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Comparison of different implant surface roughnesses and live cell response for spinal devices 不同植入物表面粗糙度与脊柱装置活细胞反应的比较

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102979

B. Cheng , A. Trivedi , J. Acosta , K. Holmberg , R. Sauber , D. Altman

引用次数: 0

Best Abstract: Less Is More: Fewer Residents Clipping More Aneurysms In The United Kingdom 最佳摘要：少即是多：在英国，更少的住院医师剪除更多的动脉瘤

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103339

Abdur Raafay Iqbal , Federica Pace , Suhaib Abualsaud , Federica Pace , Olamide Akosile , Damian Holliman , Nitin Mukerji

引用次数: 0

Age-stratified treatment variations in intracranial surgical interventions for traumatic brain injury in Europe: a prospective observational study within CENTER-TBI 欧洲脑外伤颅内手术干预的年龄分层治疗差异：CENTER-TBI 的前瞻性观察研究

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103360

Rick Vreeburg , Ranjit Singh , Jeroen van Dijck , Hugo den Boogert , John Yue , Alfonso Lagares , Alexander Younsi , Godard de Ruiter , Inge van Erp , Andrew Maas , Wilco Peul , Thomas van Essen

引用次数: 0

Trigeminal nerve electrical activity in patients with trigeminal neuralgia 三叉神经痛患者的三叉神经电活动

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103364

Eugene Lekchnov , Jamil Rzaev , Konstantin Slavin

引用次数: 0

Increased intracranial pressure in diffuse axonal injury TBI patients - A single-center retrospective study 2007-2022 弥漫性轴索损伤创伤性脑损伤患者颅内压增高 - 2007-2022 年单中心回顾性研究

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103358

Iftakher Hossain , Gustaf Westerberg , Parmenion Tsitsopoulos , Niklas Marklund

引用次数: 0

Perspectives on Professionalism in the new millennium; A tale of two continents 新千年专业精神的视角；两个大陆的故事

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103430

Katrin Rabiei , Mario Ganau , Nicolas Sampron , Selcuk Peker , Marieke Broekman , Michael Fehlings

引用次数: 0

Spinal schwannoma classification based on the presumed origin with preoperative MR images 根据术前磁共振图像的推测来源进行脊神经分裂瘤分类

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.103410

Chun Kee Chung , Tae-Shin Kim , Woon Tak Yuh , Junhoe Kim , Junghoon Han , Chang-Hyun Lee , Chi Heon Kim , Hyun Ah Kim

引用次数: 0

Term and definition of a deformity after a spine trauma: Results of an international Delphi study 脊柱创伤后畸形的术语和定义：国际德尔菲研究的结果

Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102749

E.E.A. De Gendt , S.P.J. Muijs , L.M. Benneker , F.C. Oner

Introduction

Deformity of the spinal column after trauma could lead to pain, impaired function, and may sometimes necessitate extensive and high-risk surgery. This ‘condition’ has multiple terms and definitions that are used in research and clinics. A specific term and definition of this condition however is still lacking. A uniform and internationally accepted term and definition are necessary to compare cases and treatments in the future.

Research question

Reach consensus on the term and definition of this deformity after spine trauma using a Delphi approach.

Material and methods

An ‘all-rounds invitation’ Delphi process was used in this study among a group of international experts. The first round consisted of an online survey using input from preparatory studies, a typical clinical case and ICD-11 codes. The second round showed the results in-person and discussion was encouraged. Participants voted for rejection of certain terms. In the third round the final vote took place. When >80 % of the votes was for or against a term the term was rejected or accepted.

Results

Response rate was high (≥84 %). The 3 Delphi rounds were completed. Unanimous voting led to the acceptance of the term and abbreviation as PSD. Deformity in any plane, pain, impaired function, and neurological deficit, were deemed important to include in the definition of PSD.

Discussion and conclusion

Unanimous consensus was reached on ‘Posttraumatic spinal deformity: Condition where a trauma to the spine results in a deformity in any plane and results in pain and an impaired function with or without a neurological deficit.’

导言：外伤后脊柱畸形会导致疼痛、功能受损，有时可能需要进行广泛而高风险的手术。这种 "病症 "在研究和临床上有多种术语和定义。然而，目前仍缺乏关于这种病症的专门术语和定义。研究问题采用德尔菲法就脊柱创伤后畸形的术语和定义达成共识。材料和方法在这项研究中，一组国际专家采用了 "全方位邀请 "德尔菲法。第一轮由在线调查组成，调查内容包括前期研究、典型临床病例和 ICD-11 编码。第二轮是当面展示结果并鼓励讨论。与会者投票决定是否否决某些术语。第三轮进行了最终投票。当支持或反对某个术语的票数达到 80% 时，该术语即被否决或接受。完成了 3 轮德尔菲讨论。投票结果一致同意术语和缩写为 PSD。任何平面的畸形、疼痛、功能受损和神经功能缺损都被认为是 PSD 定义中的重要内容：脊柱创伤后畸形：脊柱创伤导致任何平面的畸形，并导致疼痛和功能受损，伴有或不伴有神经功能缺损"。

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引用次数: 0

Comparing image normalization techniques in an end-to-end model for automated modic changes classification from MRI images 比较端到端模型中的图像归一化技术，实现磁共振成像模态变化自动分类

Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2023.102738

Andrea Cina , Daniel Haschtmann , Dimitrios Damopoulos , Nicolas Gerber , Markus Loibl , Tamas Fekete , Frank Kleinstück , Fabio Galbusera

Introduction

Modic Changes (MCs) are MRI alterations in spine vertebrae's signal intensity. This study introduces an end-to-end model to automatically detect and classify MCs in lumbar MRIs. The model's two-step process involves locating intervertebral regions and then categorizing MC types (MC0, MC1, MC2) using paired T1-and T2-weighted images. This approach offers a promising solution for efficient and standardized MC assessment.

Research question

The aim is to investigate how different MRI normalization techniques affect MCs classification and how the model can be used in a clinical setting.

Material and methods

A combination of Faster R–CNN and a 3D Convolutional Neural Network (CNN) is employed. The model first identifies intervertebral regions and then classifies MC types (MC0, MC1, MC2) using paired T1-and T2-weighted lumbar MRIs. Two datasets are used for model development and evaluation.

Results

The detection model achieves high accuracy in identifying intervertebral areas, with Intersection over Union (IoU) values above 0.7, indicating strong localization alignment. Confidence scores above 0.9 demonstrate the model's accurate levels identification. In the classification task, standardization proves the best performances for MC type assessment, achieving mean sensitivities of 0.83 for MC0, 0.85 for MC1, and 0.78 for MC2, along with balanced accuracy of 0.80 and F1 score of 0.88.

Discussion and conclusion

The study's end-to-end model shows promise in automating MC assessment, contributing to standardized diagnostics and treatment planning. Limitations include dataset size, class imbalance, and lack of external validation. Future research should focus on external validation, refining model generalization, and improving clinical applicability.

导言Modic Changes（MCs）是脊柱椎体信号强度的 MRI 改变。本研究介绍了一种端到端模型，用于自动检测和分类腰椎磁共振成像中的 MCs。该模型的两个步骤包括定位椎间区域，然后使用成对的 T1 和 T2 加权图像对 MC 类型（MC0、MC1、MC2）进行分类。这种方法为高效、标准化的 MC 评估提供了一种很有前景的解决方案。研究问题旨在研究不同的 MRI 归一化技术对 MC 分类的影响，以及该模型在临床环境中的应用。该模型首先识别椎间区域，然后使用成对的 T1 和 T2 加权腰椎 MRI 图像对 MC 类型（MC0、MC1、MC2）进行分类。结果该检测模型在识别椎间区域方面达到了很高的准确度，其 "交集大于联合"（Intersection over Union，IoU）值高于 0.7，表明定位对齐度很高。置信度得分超过 0.9，表明该模型能够准确识别椎间区。在分类任务中，标准化证明了 MC 类型评估的最佳性能，MC0 的平均灵敏度为 0.83，MC1 为 0.85，MC2 为 0.78，平衡准确度为 0.80，F1 得分为 0.88。不足之处包括数据集的大小、类别不平衡以及缺乏外部验证。未来的研究应侧重于外部验证、完善模型的通用性和提高临床适用性。

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引用次数: 0

Dural reconstruction with or without a bone graft of paranasal and anterior skullbase malignancies: Retrospective single-center analysis of 11 cases and review of literature 鼻旁和前颅底恶性肿瘤硬脑膜重建与否的骨移植：对11个病例的单中心回顾性分析和文献综述

Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2023.102740

Björn Sommer , Ina Konietzko , Maximilian Niklas Bonk , Tina Schaller , Bruno Märkl , Klaus Henning Kahl , Georg Stüben , Johannes Zenk , Ehab Shiban

Introduction

The reconstruction of frontobasal defects following oncologic resections of paranasal and anterior skull base (ASB) malignancies remains challenging. Ineffective reconstruction could lead to cerebrospinal fluid leak, meningitis, and tension pneumocephalus.

Research question

Aim of this investigation was to analyse postoperative complication rates with or without bone graft for anterior skull base reconstruction.

Material and methods

In this retrospective study, we included patients following resection of paranasal and/or anterior skull base malignancies between October 2013 and December 2022. Complications were analysed with regards to the type of skull base reconstruction.

Results

Eleven patients were identified (2 female, 9 male, age (median, SD) 64 ± 14.1 years (range 38–81). There were nine cases of paranasal sinus and nasal cavity carcinomas and two cases of olfactory neuroblastomas. Overall survival was 22.5 ± 28 months (range: 5–78), progression free survival was 17.0 ± 20.3 months (range: 11–78). Bone skull base reconstruction using a split graft was performed in three cases. Postoperative complications requiring surgical intervention were seen in 33% (one tension pneumocephalus) of cases in the bone reconstruction group and 50% (three patients with cerebrospinal fluid leak, one infection) in the non-bone reconstruction group.

Discussion and conclusion

The structural reinforcement of structural bone chip grafting might provide additional support of the ASB and prevent CSF leakage or encephalocele. Especially in large (>10 cm²) bone defects of advanced sinonasal malignancies extending into the middle cranial fossa, the full armamentarium of reconstruction possibilities should be considered.

导言鼻旁和前颅底（ASB）恶性肿瘤切除术后的前颅底缺损重建仍具有挑战性。材料和方法在这项回顾性研究中，我们纳入了 2013 年 10 月至 2022 年 12 月间接受副鼻腔和/或前颅底恶性肿瘤切除术的患者。结果共发现 7 名患者（2 名女性，9 名男性，年龄（中位数，标码）64 ± 14.1 岁（38-81 岁）。其中9例为鼻旁窦和鼻腔癌，2例为嗅觉神经母细胞瘤。总生存期为（22.5±28）个月（范围：5-78），无进展生存期为（17.0±20.3）个月（范围：11-78）。三例患者使用劈裂移植进行了骨颅底重建。术后需要手术干预的并发症在骨重建组中占 33%（1 例张力性气胸），在非骨重建组中占 50%（3 例脑脊液漏患者，1 例感染）。特别是对于延伸至中颅窝的晚期鼻窦鼻腔恶性肿瘤的大面积（10 平方厘米）骨缺损，应全面考虑重建的可能性。

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引用次数: 0

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