Brain & spine最新文献

英文中文

Minimally invasive posterior cervical foraminotomy versus anterior cervical fusion and arthroplasty: Systematic review and updated meta-analysis 微创颈椎后路椎板切除术与颈椎前路融合术和关节成形术的比较：系统回顾和最新荟萃分析

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102852

Hanmo Fang, Min Cui, Kangcheng Zhao, Yukun Zhang, Xianlin Zeng, Cao Yang, Lin Xie

Introduction

This study is a systematic review and meta-analysis that investigates the efficacy of different surgical methods for treating cervical disc herniation or cervical foraminal stenosis.

Research question

The research aimed to compare the efficacy of Minimally Invasive Posterior Cervical Foraminotomy (MI-PCF) with anterior approaches, namely Anterior Cervical Discectomy and Fusion (ACDF) and Cervical Disc Arthroplasty (CDA).

Material and methods

The study included a comprehensive review of eight articles that compared ACDF and MI-PCF, and four articles that compared CDA to MI-PCF.

Results

The results indicated no significant difference in surgical duration, hospital stay, complication rates, and reoperation rates between MI-PCF and ACDF. However, when comparing CDA with MI-PCF, it was found that CDA had a higher complication rate, while MI-PCF had a higher reoperation rate.

Discussion and conclusion

Despite these findings, the study recommends MI-PCF as the preferred surgical method for cervical radiculopathy, owing to the advancements in minimally invasive techniques. However, these findings are preliminary, and further research with longer follow-up periods and larger sample sizes is necessary to confirm these findings and to further explore the potential advantages and disadvantages of these surgical methods.

引言本研究是一项系统综述和荟萃分析，探讨了不同手术方法治疗颈椎间盘突出症或颈椎椎管狭窄症的疗效。研究问题本研究旨在比较微创颈椎后路椎板切除术（MI-PCF）与前路方法（即颈椎前路椎间盘切除融合术（ACDF）和颈椎间盘关节成形术（CDA））的疗效。结果表明，MI-PCF 和 ACDF 在手术时间、住院时间、并发症发生率和再次手术率方面没有显著差异。讨论与结论尽管有这些发现，但由于微创技术的进步，该研究仍建议将 MI-PCF 作为治疗颈椎病的首选手术方法。然而，这些研究结果还只是初步的，有必要进行随访时间更长、样本量更大的进一步研究，以证实这些研究结果，并进一步探讨这些手术方法的潜在优缺点。

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引用次数: 0

Decency in Neurosurgery 神经外科的体面

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2023.102744

Minaam Farooq, Hira Saleem, Amr Badary, Bipin Chaurasia

引用次数: 0

Paediatric cerebellar glioblastoma - long-term survival following surgery and adjuvant chemoradiotherapy: A case report and literature review 小儿小脑胶质母细胞瘤--手术和辅助化放疗后的长期生存：病例报告和文献综述

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102819

Matthew I. Sanders , Daniel Gatt , Victoria Lee , Stephen B. Wharton , Veejay Bagga

Introduction

Paediatric cerebellar glioblastoma is an exceptionally rare clinical entity, with very few cases described in the literature. In the majority of reported cases, prognosis is extremely poor, despite surgical and oncological management. The paucity of data results in lack of consensus as to the optimal management of these patients, with the objective of prolonging survival.

Research question

Do patient or tumour characteristics suggest more favourable rates of progression-free survival in paediatric cerebellar glioblastoma?

Material and methods

Tumour histopathology plus retrospective molecular analysis of archived samples, as well treatment strategy and patient characteristics of a six-year-old child with cerebellar glioblastoma and prolonged progression-free survival were assessed. Characteristics in the published literature that inferred prolonged survival were identified and compared.

Results

Paediatric cerebellar glioblastoma is extremely rare, with only a handful of cases reported over several decades, during which time diagnostic and therapeutic techniques have evolved markedly. Consequently, the scarcity of data with sufficient granularity means that limited conclusions can be drawn. Specific clinical and histopathological factors (i.e. female sex, young age, EGFR negativity and surgical resection plus adjuvant chemoradiotherapy) may indicate a more favourable progression-free survival.

Discussion and conclusion

Rates of progression-free survival in this rare condition are generally poor, however, several patient and tumour characteristics may infer more favourable prognosis. As increasingly refined means of diagnosis and characterisation are developed, particularly as a result of advances in molecular analyses, more adjuvant treatment options are likely to come on stream in future.

导言小脑胶质母细胞瘤是一种异常罕见的临床实体肿瘤，文献中描述的病例极少。在大多数报道的病例中，尽管进行了手术和肿瘤治疗，但预后极差。材料和方法对一名患有小脑胶质母细胞瘤并延长了无进展生存期的六岁儿童的肿瘤组织病理学、存档样本的回顾性分子分析、治疗策略和患者特征进行了评估。结果小脑胶质母细胞瘤极为罕见，几十年来仅有少数病例报道，在此期间诊断和治疗技术有了显著发展。因此，由于缺乏足够精细的数据，只能得出有限的结论。特定的临床和组织病理学因素（即女性、年轻、表皮生长因子受体阴性和手术切除加辅助化放疗）可能预示着更有利的无进展生存。随着诊断和特征描述手段的日益完善，特别是分子分析技术的进步，未来可能会出现更多的辅助治疗方案。

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引用次数: 0

Assessing the efficacy of large language models in spinal health information dissemination 评估大语言模型在脊柱健康信息传播中的功效

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102815

Aaron Lawson McLean, Christian Senft

引用次数: 0

Limitless potential within limited resources: The realm of liquid biopsy for brain tumors in low-middle-income countries 有限资源中的无限潜力：中低收入国家脑肿瘤的液体活检领域

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102817

Hafiz Sohail Ahmad, Shahryar Zafer, Haseeb Mehmood Qadri, Asif Bashir

引用次数: 0

Radioresistance in brain tumors: Strategies for improved radiotherapy outcomes 脑肿瘤的放射抗药性：改善放疗效果的策略

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102912

引用次数: 0

Brain-spine interface for movement restoration after spinal cord injury 用于脊髓损伤后运动恢复的脑脊接口

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102926

引用次数: 0

Accuracy and Safety Assessment of Subaxial Cervical Pedicle Screw Instrumentation: A Systematic Review 颈椎椎弓根螺钉植入术的准确性和安全性评估：系统回顾

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102875

引用次数: 0

Sagittal Balance analysis in young patients presenting symptomatic Lumbosacral Transitional Vertebrae, a case series 对出现症状性腰骶部过渡椎体的年轻患者进行矢状体平衡分析，病例系列

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102889

引用次数: 0

Evaluating intervertebral disc biomechanics with radiological imaging 利用放射成像评估椎间盘生物力学

IF 1.9 Q3 CLINICAL NEUROLOGY

Brain & spine

Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102884

引用次数: 0

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