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Efficacy of Respiratory Muscle Training in the Immediate Postoperative Period of Cardiac Surgery: A Systematic Review and Meta-Analysis. 心脏手术术后即刻进行呼吸肌训练的效果:系统回顾与元分析》。
Pub Date : 2024-02-05 DOI: 10.21470/1678-9741-2022-0165
Tarcísio Nema de Aquino, João Paulo Prado, Ernesto Crisafulli, Enrico Maria Clini, Giovane Galdino

Introduction: This study aimed to evaluate the efficacy of respiratory muscle training during the immediate postoperative period of cardiac surgery on respiratory muscle strength, pulmonary function, functional capacity, and length of hospital stay.

Methods: This is a systematic review and meta-analysis. A comprehensive search on PubMed®, Excerpta Medica Database (or Embase), Cumulative Index of Nursing and Allied Health Literature (or CINAHL), Latin American and Caribbean Health Sciences Literature (or LILACS), Scientific Electronic Library Online (or SciELO), Physiotherapy Evidence Database (or PEDro), and Cochrane Central Register of Controlled Trials databases was performed. A combination of free-text words and indexed terms referring to cardiac surgery, coronary artery bypass grafting, respiratory muscle training, and clinical trials was used. A total of 792 studies were identified; after careful selection, six studies were evaluated.

Results: The studies found significant improvement after inspiratory muscle training (IMT) (n = 165, 95% confidence interval [CI] 9.68, 21.99) and expiratory muscle training (EMT) (n = 135, 95% CI 8.59, 27.07) of maximal inspiratory pressure and maximal expiratory pressure, respectively. Also, IMT increased significantly (95% CI 19.59, 349.82, n = 85) the tidal volume. However, no differences were found in the peak expiratory flow, functional capacity, and length of hospital stay after EMT and IMT.

Conclusion: IMT and EMT demonstrated efficacy in improving respiratory muscle strength during the immediate postoperative period of cardiac surgery. There was no evidence indicating the efficacy of IMT for pulmonary function and length of hospital stay and the efficacy of EMT for functional capacity.

导言本研究旨在评估心脏手术术后立即进行呼吸肌训练对呼吸肌力量、肺功能、功能能力和住院时间的影响:这是一项系统综述和荟萃分析。在 PubMed®、Excerpta Medica Database(或 Embase)、Cumulative Index of Nursing and Allied Health Literature(或 CINAHL)、Latin American and Caribbean Health Sciences Literature(或 LILACS)、Scientific Electronic Library Online(或 SciELO)、Physiotherapy Evidence Database(或 PEDro)和 Cochrane Central Register of Controlled Trials 等数据库中进行了全面检索。研究中使用了有关心脏手术、冠状动脉旁路移植术、呼吸肌训练和临床试验的自由文本词和索引词。共确定了 792 项研究;经过仔细筛选,对 6 项研究进行了评估:研究发现,经过吸气肌训练(IMT)(n = 165,95% 置信区间 [CI]9.68,21.99)和呼气肌训练(EMT)(n = 135,95% 置信区间 [CI]8.59,27.07)后,最大吸气压和最大呼气压分别有明显改善。此外,IMT 还能明显增加潮气量(95% CI 19.59,349.82,n = 85)。然而,EMT 和 IMT 治疗后的呼气流量峰值、功能能力和住院时间均无差异:结论:IMT 和 EMT 有助于改善心脏手术术后初期的呼吸肌力量。没有证据表明 IMT 对肺功能和住院时间有疗效,而 EMT 对功能能力有疗效。
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引用次数: 0
Comparison of Early and Mid-Term Outcomes After Classic and Modified Morrow Septal Myectomy in Patients with Hypertrophic Obstructive Cardiomyopathy. 肥厚型梗阻性心肌病患者接受经典和改良莫洛隔膜瓣切除术后的早期和中期疗效比较
Pub Date : 2024-02-05 DOI: 10.21470/1678-9741-2023-0205
Mustafa Karaarslan, Osman Fehmi Beyazal, Mehmed Yanartaş

Introduction: The aim of our study is to compare the early and mid-term outcomes of patients with hypertrophic obstructive cardiomyopathy who underwent classic and modified Morrow septal myectomy.

Methods: Between 2014 and 2019, 48 patients (24 males; mean age 49.27±16.41 years) who underwent septal myectomy were evaluated. The patients were divided into two groups - those who underwent classic septal myectomy (n=28) and those who underwent modified septal myectomy (n=20).

Results: Mitral valve intervention was higher in the classic Morrow group than in the modified Morrow group, but there was no significant difference (P=0.42). Mortality was found to be lower in the modified Morrow group than in the classic Morrow group (P=0.01). In both groups, the mean immediate postoperative gradient was significantly higher than the mean of the 3rd and 12th postoperative months. The preoperative and postoperative gradient difference of the modified Morrow group was significantly higher than of the classic Morrow group (P<0.001).

Conclusion: Classic Morrow and modified Morrow procedures are effective methods for reducing left ventricular outflow tract obstruction. The modified Morrow procedure was found to be superior to the classic Morrow procedure in terms of reducing the incidence of mitral valve intervention with the reduction of the left ventricular outflow tract gradient.

导言我们的研究旨在比较肥厚型梗阻性心肌病患者接受经典和改良莫罗室间隔肌瘤切除术的早期和中期疗效:在 2014 年至 2019 年期间,对 48 例接受房间隔 myectomy 切除术的患者(男性 24 例;平均年龄 49.27±16.41 岁)进行了评估。患者被分为两组--接受经典房间隔肌瘤切除术的患者(28人)和接受改良房间隔肌瘤切除术的患者(20人):结果:经典莫罗组的二尖瓣介入率高于改良莫罗组,但无显著差异(P=0.42)。改良莫罗组的死亡率低于经典莫罗组(P=0.01)。在两组中,术后即刻梯度的平均值明显高于术后第3个月和第12个月的平均值。改良 Morrow 术组的术前和术后梯度差明显高于经典 Morrow 术组(P=0.01):经典莫罗术和改良莫罗术是减少左心室流出道梗阻的有效方法。在减少二尖瓣介入治疗的发生率和降低左室流出道坡度方面,改良莫罗术优于经典莫罗术。
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引用次数: 0
Our 10-Year Experience with Atrial Myxomas: Is Concurrent Valve Intervention Really Warranted? 我们治疗心房肌瘤的 10 年经验:是否真的需要同时进行瓣膜介入治疗?
Pub Date : 2024-02-05 DOI: 10.21470/1678-9741-2023-0040
Ketika Potey, Narender Jhajhria, Manish Mallik, Rahul Bhushan, Palash Aiyer, Vijay Grover

Introduction: Primary cardiac myxomas are rare tumors. Concurrent valvular lesion is a common finding on evaluation which is thought to be due to annular dilatation secondary to tumor movement across the valve, functional obstruction across the valve, and severe pulmonary hypertension secondary to chronic obstruction. A common belief among surgeons is that excision of myxoma leads to abatement of symptoms, and further valve intervention may not be warranted.

Methods: A 10-year retrospective descriptive study was designed to analyze patients who underwent excision of cardiac myxoma at our center. Data was analyzed regarding presenting features, echocardiographic findings of myxoma and valve morphology, intraoperative assessment, and postoperative outcome with/without valve repair/replacement in all patients.

Results: A total of 22 patients underwent surgery for myxoma. Six patients underwent successful mitral valve repair with ring annuloplasty, two had moderate mitral regurgitation, three had severe mitral regurgitation, and one patient had no mitral regurgitation on preoperative assessment, but moderate mitral regurgitation was found intraoperatively. Four of these patients had no residual mitral regurgitation in follow-up period while two had mild residual mitral regurgitation. One patient had severe mitral stenosis of concurrent rheumatic etiology and successfully underwent mitral valve replacement.

Conclusion: Cardiac myxomas are rare benign tumors commonly associated with mitral valve insufficiency. Mitral valve should be assessed intraoperatively after excision of mass as preoperative assessment might often be insufficient. Concomitant mitral valve intervention might be needed with a case-specific tailored approach, and mitral valve repair with ring annuloplasty offers best surgical outcome in such cases.

导言原发性心脏肌瘤是一种罕见肿瘤。并发瓣膜病变是评估时的常见发现,其原因可能是肿瘤穿过瓣膜移动导致瓣环扩张、瓣膜功能性梗阻以及慢性梗阻导致的严重肺动脉高压。外科医生普遍认为,切除肌瘤可减轻症状,因此可能不需要对瓣膜进行进一步干预:方法:我们设计了一项为期 10 年的回顾性描述性研究,对在本中心接受心脏肌瘤切除术的患者进行分析。研究分析了所有患者的发病特征、肌瘤和瓣膜形态的超声心动图检查结果、术中评估以及术后瓣膜修复/置换的结果:共有22名患者接受了肌瘤手术。结果:共有22名患者接受了肌瘤手术,其中6名患者通过环形瓣环成形术成功完成了二尖瓣修复术,2名患者二尖瓣中度反流,3名患者二尖瓣重度反流,1名患者术前评估无二尖瓣反流,但术中发现二尖瓣中度反流。其中四名患者在随访期间没有二尖瓣返流残留,两名患者有轻度二尖瓣返流残留。一名患者因并发风湿病因导致二尖瓣严重狭窄,成功接受了二尖瓣置换术:结论:心脏肌瘤是一种罕见的良性肿瘤,通常与二尖瓣功能不全有关。由于术前评估往往不够充分,因此在切除肿块后应在术中对二尖瓣进行评估。在此类病例中,二尖瓣环成形术修复二尖瓣可获得最佳手术效果。
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引用次数: 0
The Rational Contrast Between Del Nido Solution and the Approaches on Minimally Invasive Extracorporeal Technologies. 德尔尼多解决方案与体外微创技术方法的合理对比。
Pub Date : 2024-02-05 DOI: 10.21470/1678-9741-2023-0194
Ignazio Condello
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引用次数: 0
Is Deep Hypothermic Cardiac Arrest Mandatory in Aortic Arch Surgeries? 主动脉弓手术是否必须进行深低温心脏停搏?
Pub Date : 2024-02-05 DOI: 10.21470/1678-9741-2020-0465
Jignesh Kothari, Ishan Gohil, Kinneresh Baria

Cannulation strategies in aortic arch surgeries are a matter of immense discussion. Majority of time deep hypothermic circulatory arrest (DHCA) is the way out, but it does come with its set of demerits. Here we demonstrate a case with aortic arch dissection dealt with dual cannulation strategy in axillary and femoral artery without need for DHCA and ensuring complete neuroprotection of brain and spinal cord without hinderance of time factor. Inception of new ideas like this may decrease the need for DHCA and hence its drawbacks, thus decreasing the morbidity and mortality associated.

主动脉弓手术中的插管策略引起了广泛讨论。大多数情况下,深低温循环骤停(DHCA)是一条出路,但它也有其缺点。在这里,我们展示了一个主动脉弓夹层的病例,该病例采用腋动脉和股动脉双插管策略,无需深低温停循环(DHCA),就能确保大脑和脊髓得到完全的神经保护,且不受时间因素的影响。这种新思路的出现可能会减少对 DHCA 的需求,从而减少其弊端,进而降低相关的发病率和死亡率。
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引用次数: 0
Pioneer of Cardiothoracic Surgery - Luiz Tavares da Silva. 心胸外科的先驱-路易斯·塔瓦雷斯·达席尔瓦。
Pub Date : 2023-11-09 DOI: 10.21470/1678-9741-2023-0046
Ricardo de Carvalho Lima, Leonardo Pontual Lima, Mozart Augusto Soares de Escobar, José Ricardo Lagreca de Sales Cabral, José Aécio Fernandes Vieira, Guilherme Tavares da Silva Maia

Luis Tavares revolutionized cardiac surgery, always bringing the most modern instruments and equipment from his travels to England - surgical forceps, scissors, scalpels, etc. He always insisted that he was not just a thoracic surgeon, for his work extended over a wide field and created three important cardiac surgery centers which promoted a great development of cardiology. He carried out the first open heart surgery (atrial septal defect) employing extracorporeal circulation and closure of a ventricular septal defect with deep surface hypothermia of north and northeast Brazil. He promoted an intense scientific exchange program between Recife and England, resulting in significant advances in medicine, and participated directly in the creation of HEMOPE), leading to radical changes and improvements in blood therapy in the whole country. The PROCAPE, inaugurated in 2006, was the result of the cardiac center created by him in early 1970 at Hospital Oswaldo Cruz and can be considered the second largest public-university cardiology center in Brazil. He is thus widely regarded as an outstanding name in medicine in the 20th century and one of the fathers of modern cardiac surgery in Brazil.

路易斯·塔瓦雷斯(Luis Tavares)彻底改变了心脏外科,他总是从英国旅行中带来最现代化的仪器和设备——手术钳、剪刀、手术刀等。他一直坚称自己不仅仅是一名胸外科医生,因为他的工作涉及广泛的领域,并创建了三个重要的心脏外科中心,促进了心脏病学的巨大发展。他在巴西北部和东北部进行了第一次心脏直视手术(房间隔缺损),采用体外循环和深部表面低温封闭房间隔缺损。他推动了累西腓和英格兰之间的一项激烈的科学交流计划,从而在医学上取得了重大进展,并直接参与了HEOPE的创建,从而在整个国家的血液治疗方面带来了根本性的变化和改进。PROCAPE于2006年成立,是他于1970年初在奥斯瓦尔多·克鲁兹医院创建的心脏中心的成果,可以被认为是巴西第二大公立大学心脏病中心。因此,他被广泛认为是20世纪医学界的杰出人物,也是巴西现代心脏外科之父之一。
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引用次数: 0
Application of Cut-and-Sew Technique in Thoracoscopic Minimally Invasive Mitral Valve Surgery and Concomitant Maze Procedure. 切开缝合技术在胸腔镜微创二尖瓣手术中的应用。
Pub Date : 2023-11-09 DOI: 10.21470/1678-9741-2022-0456
Erlei Han, Zhifang Liu, Bing Zhou, Shuwei Wang, Zhibin Hu, Yong Cui

Introduction: Atrial fibrillation is one of the common complications of mitral valve disease. Currently, in the absence of freezing equipment, it's still impossible to fully conduct a minimally invasive Cox-maze IV procedure to treat atrial fibrillation.

Methods: We analyzed the clinical data of 28 patients who underwent thoracoscopic minimally invasive mitral valve full maze surgery in our hospital from October 2021 to September 2022; 13 patients were male and 15 were female, three suffered from paroxysmal atrial fibrillation, and 25 suffered from permanent atrial fibrillation; average age was 61.88±8.30 years, and mean preoperative left atrial diameter was 47.12±8.34 mm. Isolation of left atrial posterior wall (box lesion) was completed in all patients by cut-and-sew technique and bipolar clamp ablation.

Results: For these subjects, the median cardiopulmonary bypass time was 169 (109.75-202.75) minutes, aortic cross-clamping time was 106 (77.75-125.50) minutes, and ventilator assistance time was 6.5 (0-10) hours. Among them, eight subjects had the endotracheal tubes removed immediately after surgical operation. Three subjects were in the blanking period; two subjects still had atrial fibrillation at three months after operation, one of whom resumed sinus rhythm after electrical cardioversion therapy; and all the remaining 23 subjects had sinus rhythm.

Conclusion: The minimally invasive cut-and-sew technique for electrical isolation of left pulmonary veins can improve sinus conversion rate of patients suffering from both mitral valve disease and atrial fibrillation. In selected subjects, it is safe and has good results in the short-term postoperative period.

引言:心房颤动是二尖瓣疾病的常见并发症之一。目前,在没有冷冻设备的情况下,仍然不可能完全进行微创Cox迷宫IV手术来治疗心房颤动。方法:分析2021年10月至2022年9月在我院行胸腔镜微创二尖瓣全迷宫手术的28例患者的临床资料;13例为男性,15例为女性,3例为阵发性心房颤动,25例为永久性心房颤动;平均年龄61.88±8.30岁,术前左心房平均直径47.12±8.34mm。所有患者均采用切开缝合技术和双极夹刀消融完成左心房后壁(箱形病变)的隔离。结果:这些受试者的中位体外循环时间为169(109.75-202.75)分钟,主动脉阻断时间为106(77.75-125.50)分钟,呼吸机辅助时间为6.5(0-10)小时。其中,8名受试者在手术后立即取出气管插管。三名受试者处于空白期;两名受试者在术后三个月仍有心房颤动,其中一人在电复律治疗后恢复窦性心律;其余23例均为窦性心律。结论:微创左肺静脉切开缝合电隔离技术可提高二尖瓣疾病和心房颤动患者的窦性转换率。在选定的受试者中,它是安全的,并且在短期术后期间具有良好的效果。
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引用次数: 0
Performance Evaluation of Geometrically Different Pediatric Arterial Cannulae in a Pediatric Cardiopulmonary Bypass Model. 不同几何形状的儿童动脉插管在儿童体外循环模型中的性能评估。
Pub Date : 2023-11-09 DOI: 10.21470/1678-9741-2023-0110
Gabriela B de O Carvalho, Luiz Fernando Caneo, Gregory Matte, Caio Henrique de A Cruz, Everton Neri da Silva, Luciana P Carletto, Ana Vitória C X de Castro, Betina G Madueño Silva, Valéria C Policarpo, Idágene A Cestari, Fabio B Jatene, Marcelo Biscegli Jatene

Objective: To define a reference chart comparing pressure drop vs. flow generated by a set of arterial cannulae currently utilized in cardiopulmonary bypass conditions in pediatric surgery.

Methods: Cannulae from two manufacturers were selected considering their design and outer and inner diameters. Cannula performance was evaluated in terms of pressure drop vs. flow during simulated cardiopulmonary bypass conditions. The experimental circuits consisted of a Jostra HL-20 roller pump, a Quadrox-i pediatric oxygenator (Maquet Cardiopulmonary AG, Rastatt, Germany), and a custom pediatric tubing set. The circuit was primed with lactated Ringer's solution only (first condition) and with human packed red blood cells added (second condition) to achieve a hematocrit of 30%. Cannula sizes 8 to 16 Fr were inserted into the cardiopulmonary bypass circuit with a "Y" connector. The flow was adjusted in 100 ml/min increments within typical flow ranges for each cannula. Pre-cannula and post-cannula pressures were measured to calculate the pressure drop.

Results: Utilizing a pressure drop limit of 100 mmHg, our results suggest a recommended flow limit of 500, 900, 1400, 2600, and 3100 mL/min for Braile arterial cannulae sizes 8, 10, 12, 14, and 16 Fr, respectively. For Medtronic DLP arterial cannulae sizes 8, 10, 12, 14, and 16 Fr, the recommended flow limit is 600, 1100, 1700, 2700, and 3300 mL/min, respectively.

Conclusion: This study reinforces discrepancies in pressure drop between cannulae of the same diameter supplied by different manufacturers and the importance of independent translational research to evaluate components' performance.

目的:定义一个参考图,比较目前在儿科手术体外循环条件下使用的一套动脉插管产生的压降与流量。方法:选择两个制造商的套管,考虑其设计以及外径和内径。根据模拟体外循环条件下的压降与流量来评估插管性能。实验回路由Jostra HL-20滚轴泵、Quadrox-i儿童氧合器(Maquet Cardiopulous AG,Rastatt,Germany)和定制的儿童导管组组成。仅用乳酸林格溶液(第一种条件)和添加人填充红细胞(第二种条件)对回路进行预处理,以实现30%的红细胞压积。使用“Y”连接器将尺寸为8-16Fr的套管插入体外循环回路。在每个套管的典型流量范围内以100毫升/分钟的增量调节流量。测量插管前和插管后的压力以计算压降。结果:使用100 mmHg的压降限值,我们的结果表明,对于大小为8、10、12、14和16Fr的Braile动脉插管,建议的流量限值分别为500、900、1400、2600和3100 mL/min。对于尺寸为8、10、12、14和16Fr的美敦力DLP动脉插管,建议的流量限制分别为600、1100、1700、2700和3300 mL/min。结论:本研究强调了不同制造商提供的相同直径套管之间压降的差异,以及独立转化研究对评估组件性能的重要性。
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引用次数: 0
Acute Aortic Dissection Type A in Younger Patients (< 60 Years Old) - Does Full Arch Replacement Provide Benefits Compared to Limited Approach? 年轻患者(<60岁)的急性A型主动脉夹层-与有限入路相比,全足弓置换术有好处吗?
Pub Date : 2023-11-09 DOI: 10.21470/1678-9741-2022-0434
Ruslan Natanov, Malakh Lal Shrestha, Andreas Martens, Erik Beckmann, Heike Krueger, Morsi Arar, Linda Rudolph, Stefan Ruemke, Reza Poyanmehr, Wilhelm Korte, Tobias Schilling, Axel Haverich, Tim Kaufeld

Introduction: Acute aortic dissection Stanford type A (AADA) is a surgical emergency associated with high morbidity and mortality. Although surgical management has improved, the optimal therapy is a matter of debate. Different surgical strategies have been proposed for patients under 60 years old. This paper evaluates the postoperative outcome and the need for secondary aortic operation after a limited surgical approach (proximal arch replacement) vs. extended arch repair.

Methods: Between January 2000 and January 2018, 530 patients received surgical treatment for AADA at our hospital; 182 were under 60 years old and were enrolled in this study - Group A (n=68), limited arch repair (proximal arch replacement), and group B (n=114), extended arch repair (> proximal arch replacement).

Results: More pericardial tamponade (P=0.005) and preoperative mechanical resuscitation (P=0.014) were seen in Group A. More need for renal replacement therapy (P=0.047) was seen in the full arch group. Mechanical ventilation time (P=0.022) and intensive care unit stay (P<0.001) were shorter in the limited repair group. Thirty-day mortality was comparable (P=0.117). New onset of postoperative stroke was comparable (Group A four patients [5.9%] vs. Group B 15 patients [13.2%]; P=0.120). Long-term follow-up did not differ significantly for secondary aortic surgery.

Conclusion: Even though young patients received only limited arch repair, the outcome was comparable. Full-arch replacement was not beneficial in the long-time follow-up. A limited approach is justified in the cohort of young AADA patients. Exemptions, like known Marfan syndrome and the presence of an intimal tear in the arch, should be considered.

简介:斯坦福A型急性主动脉夹层(AADA)是一种与高发病率和死亡率相关的外科急诊。尽管手术管理有所改善,但最佳治疗方法仍存在争议。针对60岁以下的患者提出了不同的手术策略。本文评估了有限手术入路(近端足弓置换术)与扩大足弓修复术后的术后结果和二次主动脉手术的必要性。方法:2000年1月至2018年1月,530例患者在我院接受AADA手术治疗;182名60岁以下的患者被纳入本研究——A组(n=68),有限足弓修复(近端足弓置换术),B组(n=114),扩大足弓修复术(>近端足趾置换术)。结果:A组心包填塞(P=0.005)和术前机械复苏(P=0.014)较多。全足弓组更需要肾脏替代治疗(P=0.047)。机械通气时间(P=0.022)和重症监护室住院时间(P结论:尽管年轻患者只接受了有限的足弓修复,但结果是可比的。全足弓置换术在长期随访中没有益处。在年轻AADA患者队列中,有限的方法是合理的。应考虑豁免,如已知的Marfan综合征和足弓内膜撕裂。
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引用次数: 0
Treatment For Infected Frozen Elephant Trunk Prosthesis Caused by Propionibacterium acnes: A Surgical Challenge. 痤疮丙酸杆菌致冷冻象鼻假体感染的治疗:外科挑战。
Pub Date : 2023-11-09 DOI: 10.21470/1678-9741-2023-0186
Laura Varela Barca, Laura Esteban-Lucia, Marta Tomás-Mallebrera, Ana Pello-Lázaro, Gonzalo Aldámiz-Echevarría

In this article, we present the case of a 47-year-old man who underwent Bentall-Bono procedure and frozen elephant trunk prosthesis implantation due to severe aortic regurgitation and aortic dilatation with a second-time endovascular stent-graft repair in descending aorta. Over eight years, a subacute graft infection by Propionibacterium acnes was developed, culminating in cardiogenic shock secondary to severe aortic regurgitation due to a complete aortic root dehiscence because of multiple aortic pseudoaneurysms. The patient underwent emergency surgery in which the replacement of the graft by a biological valve tube was performed accompanied by a complete debranching of the three supra-aortic vessels.

在这篇文章中,我们介绍了一名47岁的男子的病例,他因严重的主动脉反流和主动脉扩张而接受了Bentall-Bono手术和冷冻象鼻假体植入,并在降主动脉进行了第二次血管内支架移植物修复。在八年多的时间里,出现了痤疮丙酸杆菌的亚急性移植物感染,最终导致心源性休克,继发于多个主动脉假性动脉瘤导致的主动脉根部完全裂开导致的严重主动脉反流。患者接受了紧急手术,用生物瓣膜管替换移植物,同时彻底清除三条主动脉上血管的分支。
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引用次数: 0
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Brazilian journal of cardiovascular surgery
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