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Multidisciplinary management of a gastric metastasis of uveal melanoma presenting 12 years after enucleation. 葡萄膜黑素瘤胃转移的多学科治疗,摘除后12年。
S Sofos, J S Azagra, L Arru, F Ries, P Leider, J Weber, M Goergen
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引用次数: 0
Music and elderly. 音乐和老年人。
J C Leners

Since more than 3 decades now, music with seniors (or younger persons), either as an educational or recreational activity, but also as a therapeutically approach has progressed. Even nowadays, in the medical field, more and more studies prove its efficiency as complementary therapy with no known side-effects. The areas where music therapy has a positive outcome, reach from pulmonary disorders to a lot of neurological chronic diseases, including aphasia, dementia or Parkinson. And at the end of life, music therapy has found a remarkable place for expressing or supporting strong emotional feelings. Evidence-based results on physiological and hormonal changes will also be reviewed.

30多年来,老年人(或年轻人)的音乐,无论是作为一种教育或娱乐活动,还是作为一种治疗方法,都取得了进展。即使在今天,在医学领域,越来越多的研究证明了它作为一种补充疗法的有效性,而且没有已知的副作用。音乐疗法有积极效果的领域,从肺部疾病到许多神经慢性疾病,包括失语症、痴呆症或帕金森症。在生命的尽头,音乐疗法已经找到了表达或支持强烈情感的绝佳场所。还将回顾生理和激素变化的循证结果。
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引用次数: 0
[Giant melanoma of the scalp: Case report]. [头皮巨大黑色素瘤:病例报告]。
N Calteux, G Berchem, N Schmid, J Nebendahl, G Fischer

We present a case of giant melanoma of the scalp observed in our department. It is a rare but very aggressive pathology which is generally treated by radical surgery. We emphasize early diagnosis because a large extension of the tumor can lead to the need of a very extensive surgical resection. Prognosis is very severe despite adjuvant medical treatments.

我们报告一例在我科观察到的巨大的头皮黑色素瘤。这是一种罕见但具有侵袭性的病理,通常通过根治性手术治疗。我们强调早期诊断,因为肿瘤的大面积扩展可能导致需要非常广泛的手术切除。尽管进行了辅助治疗,但预后非常严重。
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引用次数: 0
[Prion diseases]. 朊病毒疾病。
Pub Date : 2012-06-08 DOI: 10.1542/9781581107357-part03-prion
F. Jacob
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引用次数: 0
DTI of the visual pathway in cerebral lesions. 脑病变中视觉通路的DTI。
A Hana, A Husch, A Hana, H Boecher-Schwarz, F Hertel

Diffusion tensor imaging (DTI) can be used to localise the visual pathway (VP). In the service of the neurosurgery we have been working since the beginning of this year to develop a protocol which is suitable for the every day clinical routine to show the tracts of the white matter. Many lesions of the brain concern the white matter. Up to date it is still difficult to portray the visual pathway. Many centers all around the world are actually trying to localize the visual pathway, yet it is still used for the research. The application of the DTI-data for surgical interventions remains still a rarity. We believe that using this technique it would reduce the intraoperative risk and improve the postoperative outcome. From the beginning of this year we have been able to localize the visual pathway in 14 patients with different illnesses and we performed also postoperative controls. Using this new technique we were able to minimize the intraoperative risk in our patients.

弥散张量成像(Diffusion tensor imaging, DTI)可用于视觉通路的定位。在神经外科的服务中,我们从今年年初开始就在研究一种适合于日常临床常规的方案来显示白质束。大脑的许多损伤都与白质有关。到目前为止,仍然很难描绘视觉通路。世界各地的许多研究中心实际上都在尝试定位视觉通路,但它仍然被用于研究。dti数据在外科干预中的应用仍然很少见。我们相信使用这种技术可以降低术中风险,改善术后预后。从今年年初开始,我们已经能够定位14名不同疾病患者的视觉通路,我们也进行了术后控制。使用这项新技术,我们能够将患者的术中风险降到最低。
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引用次数: 0
Impact of initial intervention on long-term neurological recovey after cardiac arrest: data from the Luxembourg "North Pole" cohort. 初步干预对心脏骤停后长期神经系统恢复的影响:来自卢森堡“北极”队列的数据。
P Stammet, D Collas, C Werer, L Muenster, C Clarens, D Wagner

Background: Prognosis after cardiac arrest is variable and difficult to predict. Early prognostic markers would facilitate the care of these patients.

Aims: Therefore, we evaluated the impact of initial interventions after resuscitation on neurological outcome at 6 months.

Material and methods: We conducted a retrospective analysis of the patient charts from consecutive cardiac arrest patients admitted to our intensive care unit and treated with induced hypothermia.

Results: Over a 3-year period, 90 patients were included in our study. Sixty-four percent of the patients had bystander cardio-pulmonary resuscitation. An automated external defibrillator (AED) was used in 19% of the patients and the mean time to first defibrillation was 11 +/- 8.9 minutes. Patients being resuscitated and defibrillated by bystanders did better than those who had CPR only and far better than those patients in whom no rescue measures where attempted at all (73% vs. 56% vs. 32% for good neurological outcome, respectively, p= 0.03). Witnessed cardiac arrest was more frequent in patients with a good outcome than in those who collapsed without a witness (91% vs 75%, p = 0.03). In 76% of the patients with good outcome, CPR was performed whereas only 52% benefited from these measures in the bad outcome group (p = 0.01). Although the use of an AED was not significantly different between good and bad outcome groups (26% vs. 11%, p = 0.06), time to first defibrillation was significantly lower in patients with good outcome (8.7 +/- 6.3 vs. 13.3 +/- 11.3 minutes, p = 0.05). In the 17 patients in whom an AED was used, 12 (71%) recovered without major sequelae whereas in the 73 cases where no AED was used, only 34 (47%) had a good outcome (p = 0.06). At 6 months follow-up, 46 (51%) survivors had a good outcome (cerebral performance category 1-2), 5 (6%) survived with severe neurological sequelae or stayed in coma and 39 (43%) died.

Conclusions: Our local data confirm that early interventions have a major impact on survival of cardiac arrest patients. Efforts should concentrate on delivering rapid and high quality CPR as well as early defibrillation by AED's to every patient in cardiac arrest. Besides large scale Basic life support training, the introduction of dispatcher assisted CPR and the implementation and use of public AED's could considerably help to improve outcome in these patients.

背景:心脏骤停后的预后是多变且难以预测的。早期预后指标将有助于这些患者的护理。目的:因此,我们评估复苏后初始干预对6个月时神经预后的影响。材料和方法:我们对入住重症监护室并采用诱导性低温治疗的连续心脏骤停患者的病历进行了回顾性分析。结果:在3年的时间里,我们的研究纳入了90例患者。64%的患者进行了旁观者心肺复苏。19%的患者使用自动体外除颤器(AED),首次除颤平均时间为11 +/- 8.9分钟。由旁观者进行复苏和除颤的患者比仅进行心肺复苏术的患者表现更好,远好于根本没有尝试任何抢救措施的患者(良好神经预后分别为73% vs 56% vs 32%, p= 0.03)。结果良好的患者比无目击者的患者心脏骤停更频繁(91% vs 75%, p = 0.03)。在76%的预后良好的患者中,实施了心肺复苏术,而在预后不良组中,只有52%的患者从这些措施中受益(p = 0.01)。虽然AED的使用在好结果组和坏结果组之间没有显著差异(26% vs. 11%, p = 0.06),但好结果组患者首次除颤时间明显更短(8.7 +/- 6.3 vs. 13.3 +/- 11.3分钟,p = 0.05)。在17例使用AED的患者中,12例(71%)无严重后遗症,而在73例未使用AED的患者中,只有34例(47%)预后良好(p = 0.06)。在6个月的随访中,46例(51%)幸存者预后良好(脑功能分类1-2),5例(6%)存活并伴有严重的神经系统后遗症或保持昏迷,39例(43%)死亡。结论:我们的本地数据证实,早期干预对心脏骤停患者的生存有重要影响。努力应该集中在提供快速和高质量的心肺复苏术,以及通过AED对每一个心脏骤停患者进行早期除颤。除了大规模的基础生命支持培训外,引入调度员辅助心肺复苏术以及实施和使用公共AED可以显著改善这些患者的预后。
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引用次数: 0
[The Luxembourg Society for Sports Medicine (SLM) after 60 years]. [60年后的卢森堡运动医学协会]。
Charles Delagardelle

This review will mainly focus the last 10 years of the society's history because several important changes occurred during this relatively short period. The most important was the creation of the first clinical sports medicine department in Luxembourg in 2004. This modern new infrastructure was made possible by the recruitment of 2 highly competent sports physicians, the excellent collaboration of the governing board of the Centre Hospitalier de Luxembourg (CHL) and the support of the sports minister. In 2008 the new department received the label "Medical Olympic Centre of Luxembourg". One year later a Research Lab of Sports Medicine (CRP-Santé) completed the new concept. Thus within 4 years the structure of Luxembourgish sports medicine was completely rearranged and includes today orthopaedic surgery and traumatology, functional rehabilitation, sports cardiology, exercise physiology, physiotherapy and specific sports medicine research. An important new challenge of the SLMS will be to integrate the external sports physicians into this new infrastructure. Another ongoing mission of the SLMS will be the education and training of new young sports medicine specialists. Here the new department could play an outstanding role and the SLMS is in close negotiations with the University of Luxembourg, in charge of academic education in Luxembourg. A recruitment of new young sports physicians is necessary to perpetuate the routine sports medicine exams in the 15 regional centres in Luxembourg, where such an exam is mandatory in order to get an official sports licence. Since 2010 an ECG exam has been added for all new licence candidates, according to the recent recommendations of the scientific societies. New young sports physicians will also be needed to assure the medical attendance of the different national teams of Luxembourg. Until 1985 these activities were confined only to the Olympic teams every 4 years, but since the implementation of the Games of the Small European Countries in 1985, where rather big teams represent Luxembourg every two years, this mission has become more important. The history of the SLMS reflects the development both of sports and sports medicine during the last 60 years. At the beginning of the 21.century sports medicine is well settled in the Grand-duchy of Luxembourg.

这篇综述将主要集中在过去10年的社会历史,因为在这段相对较短的时间内发生了一些重要的变化。最重要的是2004年在卢森堡建立了第一个临床运动医学部门。这一现代化的新基础设施是通过招募两名非常称职的体育医生、卢森堡医院中心(CHL)管理委员会的出色合作和体育部长的支持实现的。2008年,新部门获得了"卢森堡奥林匹克医疗中心"的称号。一年后,运动医学研究实验室(crp - sant)完成了这个新概念。因此,在4年内,卢森堡运动医学的结构被完全重新安排,包括今天的矫形外科和创伤学,功能康复,运动心脏病学,运动生理学,物理疗法和特定的运动医学研究。SLMS的一个重要的新挑战将是将外部运动医生整合到这个新的基础设施中。SLMS的另一项正在进行的任务是教育和培训新的年轻运动医学专家。在这方面,新的部门可以发挥突出的作用,SLMS正在与负责卢森堡学术教育的卢森堡大学进行密切谈判。必须征聘新的年轻运动医生,以便在卢森堡的15个区域中心持续进行常规运动医学考试,在卢森堡,要获得正式的运动执照,必须进行这种考试。根据科学协会最近的建议,自2010年以来,所有新的执照候选人都增加了心电图检查。还需要新的年轻体育医生,以确保卢森堡不同国家队的医疗服务。直到1985年,这些活动仅限于每四年一次的奥运会代表队,但自从1985年开始举办欧洲小国运动会以来,卢森堡每两年有相当大的代表队参加,这一使命变得更加重要。SLMS的历史反映了运动和运动医学在过去60年的发展。在21的开始。世纪运动医学在卢森堡大公国扎根。
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引用次数: 0
[Can one authorize oocyte donation in the Grand Duchy of Luxembourg?]. 【在卢森堡大公国可以授权捐赠卵子吗?】
J Arendt

In the case of early ovary extinction, the only way to have a child is either adoption or egg/embryo reception by donation. To day, egg donation is prohibited in Luxembourg by ministerial decision in 2003. Germ cell donation is part of artificial reproductive therapy. Oocyte donation, in particular, needs to be done by IVF treatment, which makes it more complicated then sperm donation What makes it more difficult is the fact that there are no oocyte bank yet. Today, prohibition encourages procreative tourism what only wealthy people can afford. Although donation programs are well established many questions arise about egg donation such as refunds, divulging information, women's age limit, health insurance participation.

在卵巢早期消失的情况下,要孩子的唯一方法要么是收养,要么是捐赠卵子/胚胎。时至今日,根据2003年的部长决定,卵子捐赠在卢森堡是被禁止的。生殖细胞捐献是人工生殖治疗的一部分。特别是卵子捐赠,需要通过体外受精治疗,这使得它比精子捐赠更复杂,更困难的是目前还没有卵子库。如今,禁令鼓励了只有富人才能负担得起的生育旅游。尽管捐赠计划已经建立起来,但关于卵子捐赠仍存在许多问题,如退款、信息泄露、女性年龄限制、健康保险参与等。
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引用次数: 0
[The dependence level of the elderly person influences the risk of infection]. [老年人的依赖程度影响感染风险]。
B Wiedenkeller, F Modert, I Karleskind

Objective: Assess the impact of the reduction or loss of autonomy of the elderly in the nosocomial infection risk.

Method: Using Karnosfsky scale (KPS). This study involved 163 patients aged 65 and over hospitalized for medical reasons.

Data collection: KPS index, body mass index, Index Norton, bladder's drainage system at the entrance and during hospitalization, colonization of resistant bacteria (BMR) at entry and during hospitalization, antibiotic use at entry and during hospitalization, infection at entry and during hospitalization.

Results: There is a statistically significant relationship between the degree of autonomy and the index of risk of pressure ulcers (Norton), between the degree of autonomy and the use of bladder's drainage system, between the degree of autonomy and risk acquisition of BMR, between the degree of autonomy and the nosocomial infection risk.

Conclusion: The level of dependence increases the risk of infection nosocomial: loss of autonomy is a risk factor for infection. The evaluation of the degree o autonomy of elderly patients at entry and at regular intervals is essential in ou view a policy of reducing nosocomial infections.

目的:评价老年人自主性降低或丧失对医院感染风险的影响。方法:采用Karnosfsky量表(KPS)。这项研究涉及163名65岁及以上因医疗原因住院的患者。数据收集:KPS指数、体重指数、诺顿指数、入院时和住院期间膀胱引流系统、入院时和住院期间耐药菌(BMR)定植、入院时和住院期间抗生素使用、入院时和住院期间感染。结果:自主程度与压疮风险指数(Norton)、自主程度与膀胱引流系统使用、自主程度与BMR风险获得、自主程度与医院感染风险之间均有统计学意义。结论:依赖程度增加了医院感染的风险,丧失自主能力是感染的危险因素。在我们看来,在减少医院感染的政策中,在入院时和定期评估老年患者的自主程度是必不可少的。
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引用次数: 0
Transpatellar access for intramedullary stabilisation of the tibia. 经髌入路用于胫骨髓内稳定。
T Gerich, F Backes, D Pape, R Seil

Postoperative deformities of the knee and sequaelae after intraarticular surgery can interfere with a standard parapetallar approach for intramedullary stabilisation of the tibia. Even the suprapatellar approach can be rendered impossible. For these rare indications we describe the patella osteotomy and transpatellar approach.

膝关节术后畸形和关节内手术后的后遗症可能会影响胫骨髓内稳定的标准股骨旁入路。甚至髌上入路也不可能。对于这些罕见的适应症,我们描述髌骨截骨和经髌入路。
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引用次数: 0
期刊
Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg
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