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Surgical site infection prevention initiative - patient attitude and compliance. 手术部位感染预防的主动性-患者态度和依从性。
Nicholas Ramos, Faith Skeete, Janet P Haas, Lorraine Hutzler, James Slover, Michael Phillips, Joseph Bosco

Background: Although the effect of Staphylococcus aureus (SA) decolonization on surgical site infection (SSI) rates has been studied, patient tolerance and acceptance of these regimens has not been assessed. Surgical patients at our hospital's Pre-Admission Testing Clinic (PAT) receive SA reduction protocols instructing the preoperative use of chlorhexidine gluconate (CHG) soap and intranasal mupirocin ointment (MO). Certain insurers do not cover MO costs resulting in out of pocket (OOP) expenses for some patients.

Objective: This study assessed patient attitudes and compliance with our hospital's SA decolonization regimen.

Methods: One-hundred-forty-six patients received surveys. Descriptive statistics were used for analysis.

Results: Of respondents fitting inclusion criteria, 81% followed the MO protocol (MO users) while 89% followed the CHG protocol (CHG users). Fifty-four percent of MO users reported OOP expenses and 13% reported a hard or very hard financial burden. Ninety-three percent of CHG users reported the protocol was easy or very easy to follow.

Conclusion: Eighty-one percent of patients receiving the SA protocol were fully compliant despite cost or difficulty obtaining MO. Given these barriers and some difficulty with CHG application, we hypothesize compliance may be improved if MO is provided to patients without OOP expenses and if the CHG application method is simplified.

背景:虽然已经研究了金黄色葡萄球菌(SA)去菌落对手术部位感染(SSI)率的影响,但尚未评估患者对这些方案的耐受性和接受度。我院入院前检查门诊(PAT)的外科患者接受SA降低方案,指导术前使用葡萄糖酸氯己定(CHG)肥皂和鼻内莫匹罗星软膏(MO)。某些保险公司不承担MO费用,导致一些患者的自费(OOP)费用。目的:本研究评估患者对我院SA去殖民化方案的态度和依从性。方法:对146例患者进行问卷调查。采用描述性统计进行分析。结果:符合纳入标准的受访者中,81%的人遵循MO方案(MO用户),89%的人遵循CHG方案(CHG用户)。54%的MO用户报告了OOP费用,13%的用户报告了严重或非常严重的财务负担。百分之九十三的CHG用户报告说,该方案很容易或非常容易遵循。结论:81%接受SA方案的患者完全依从,尽管成本或难以获得MO。考虑到这些障碍和CHG应用的一些困难,我们假设如果向患者提供MO而不需要OOP费用,并简化CHG应用方法,可能会提高依从性。
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引用次数: 0
The diagnosis and management of spontaneous and post-arthroscopy osteonecrosis of the knee. 膝关节自发性骨坏死和关节镜后骨坏死的诊断和治疗。
Eric J Strauss, Richard Kang, Charles Bush-Joseph, Bernard R Bach

Spontaneous osteonecrosis of the knee (SPONK) and osteo necrosis in the postoperative knee (ONPK) are two clinical entities that have the potential to cause significant morbidity in affected patients. In addition to the knowledge of the patient population at risk and the classic presentation and imaging characteristics of SPONK and ONPK, the treating orthopaedic surgeon needs to maintain a high index of suspicion for these disorders since early diagnosis and treatment may allow for an improved clinical outcome. The following review presents the current knowledge regarding these two pathological processes of the knee.

自发性膝关节骨坏死(SPONK)和术后膝关节骨坏死(ONPK)是两种有可能导致患者显著发病率的临床实体。除了了解高危患者人群以及SPONK和ONPK的典型表现和影像学特征外,治疗骨科医生还需要对这些疾病保持高度的怀疑,因为早期诊断和治疗可能会改善临床结果。下面的综述介绍了目前关于这两种膝关节病理过程的知识。
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引用次数: 0
Anterior shoulder instability - a history of arthroscopic treatment. 前肩不稳-关节镜治疗史。
E Jeffrey Pope, James P Ward, Andrew S Rokito

The glenohumeral joint is the most commonly dislocated joint in the body. The prevalence of this condition and the instability that may result from it has been a focus of diagnosis and treatment since the original description of the Bankart lesion in 1923. Now, with the introduction of MRI, lesions causing anterior shoulder instability can be diagnosed more accurately. This has led to improved understanding of the pathoanatomy that must be addressed and corrected during surgical repair. Initial attempts at arthroscopic treatment, including staple repair, transosseus suture repair, rivets, and thermal capsulorraphy were fraught with complications and unacceptably high recurrence rates. The development of arthroscopic suture anchors have revolutionized the treatment of anterior shoulder instability, such that arthroscopic management is now the standard of care. In the hands of experienced surgeons, outcomes for arthroscopic treatment of shoulder instability now approaches the success of open treatment.

盂肱关节是人体最常见的脱位关节。自1923年Bankart病变的最初描述以来,这种疾病的患病率和可能导致的不稳定性一直是诊断和治疗的焦点。现在,随着MRI的引入,引起前肩不稳的病变可以更准确地诊断出来。这导致了对手术修复中必须解决和纠正的病理解剖的更好理解。关节镜治疗的最初尝试,包括钉钉修复、经骨缝合修复、铆钉和热荚膜术,都充满了并发症和令人难以接受的高复发率。关节镜缝合锚的发展已经彻底改变了前肩不稳的治疗,因此关节镜治疗现在是标准的护理。在经验丰富的外科医生手中,关节镜治疗肩部不稳定的结果现在接近开放治疗的成功。
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引用次数: 0
Sliding of two lag screw designs in a highly comminuted fracture model. 高度粉碎性断裂模型中两个拉力螺杆的滑动设计。
Frederick J Kummer, Ran Schwarzkopf, Richelle C Takemoto, Kenneth A Egol

A fracture construct, representing a worst-case model of a comminuted intertrochanteric fracture, was created in order to compare the fixation stability of two different cephalomedullary nails: one where the lag screw can telescope within itself to achieve displacement of the head-neck fragment, and the other where the solid lag screw slides only. After nail fixation, the models were loaded and then cycled, and positions of the head-neck fragment and lag screw were determined. Both nails similarly acted to limit motion of the head-neck fragment by the sliding of their lag screws, causing impingement of the fragment against the nail. Fragment movement was achieved with significantly less force with the telescoping lag screws, which also showed no final lateral projection from the nail. This was in contrast to the solid lag screws that demonstrated lateral projection in all cases.

为了比较两种不同的头髓钉的固定稳定性,我们创建了一种骨折结构,代表了粉碎性转子间骨折的最坏情况模型:一种是拉力螺钉可以在其内部伸缩以实现头颈碎片的移位,而另一种是固体拉力螺钉只能滑动。钉固定后,对模型进行加载循环,确定头颈碎片和拉力螺钉的位置。两枚钉子都通过滑动螺钉来限制头颈碎片的运动,导致碎片撞击钉子。使用伸缩式拉力螺钉,碎片的移动可以用更小的力实现,也没有显示出最终的侧向突出。这与在所有病例中显示外侧突出的实螺钉形成对比。
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引用次数: 0
The first 100 fully porous-coated femoral components in hip resurfacing. 髋关节表面置换术中的前100个全多孔涂层股骨假体。
Thomas P Gross, Fei Liu

Unlabelled: Uncemented fixation of implants to bone is a proven technology in traditional hip arthroplasty surgery. However, cement fixation is currently the standard method for the femoral component in hip resurfacing. The purpose of this study was to evaluate the performance of uncemented fixation of the femoral component in the first 100 fully porous-coated metal-on-metal hip resurfacing arthroplasties at a minimum follow-up of 2 years.

Materials and methods: From March to October 2007, 100 consecutive uncemented metal-on-metal hip resurfacing arthroplasties in 95 patients (74 males and 21 females) were implanted by the same surgeon, using bone ingrowth technology for both femoral and acetabular components. The posterior minimally invasive approach was utilized in all cases. The primary diagnosis was osteoarthritis in 72% of cases, but other diagnoses were not excluded for the purposes of this study. The mean femoral component size was 51 ± 4 millimeters, and patients were not excluded for small component size.

Results: The mean follow-up was 2.9 ± 0.2 years. The mean pre-operative Harris hip score was 57 ± 13 and improved to 96 ± 6 at the final follow-up visit. The mean UCLA activity score was 8 ± 2. There were two failures (2%): one femoral neck fracture at 2 months and one femoral component loosening at 12 months postoperatively.

Conclusion: The study demonstrated that fully porous-coated femoral resurfacing components have equivalent results to those reported for cemented femoral components at short-term follow-up. This suggests that the femoral head can reliably achieve bone ingrowth into a fully porous-coated femoral component. This encourages us to continue utilizing this bone ingrowth technique as an alternative to cement in this young and active patient group. Long-term follow-up will be needed.

无标记:在传统的髋关节置换术中,无骨水泥固定植入物是一项成熟的技术。然而,水泥固定是目前髋关节置换术中股骨假体的标准方法。本研究的目的是评估前100例全多孔涂层金属对金属髋关节置换术中非骨水泥固定股骨假体的性能,随访时间至少为2年。材料和方法:2007年3月至10月,同一位外科医生对95例患者(男性74例,女性21例)进行了100例非骨水泥金属对金属髋关节置换术,股骨和髋臼假体均采用骨长入技术。所有病例均采用后路微创入路。72%的病例最初诊断为骨关节炎,但本研究并未排除其他诊断。股骨假体的平均尺寸为51±4毫米,假体较小的患者不被排除在外。结果:平均随访2.9±0.2年。术前Harris髋关节平均评分为57±13分,最终随访时提高至96±6分。平均UCLA活动评分为8±2分。2例失败(2%):1例术后2个月股骨颈骨折,1例术后12个月股骨假体松动。结论:该研究表明,在短期随访中,全多孔涂层股骨表面置换假体与骨水泥股骨假体具有相同的结果。这表明股骨头可以可靠地实现骨长入到一个完全多孔涂层的股骨组件中。这鼓励我们在年轻活跃的患者群体中继续使用骨长入技术作为骨水泥的替代方法。需要长期随访。
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引用次数: 0
Early outcomes of sequentially cross-linked thin polyethylene liners with large diameter femoral heads in total hip arthroplasty. 大直径股骨头序贯交联聚乙烯衬垫在全髋关节置换术中的早期疗效。
Siraj A Sayeed, Michael A Mont, Christopher R Costa, Aaron J Johnson, Qais Naziri, Peter M Bonutti, Ronald E Delanois

Unlabelled: Two important issues affecting the outcome of total hip arthroplasty have been dislocation and wear, despite excellent clinical results. Larger femoral heads have had success in decreasing dislocation rates; however, there are concerns regarding the subsequent use of thinner polyethylene liners, and their effects on wear rates. Historically, high stresses on thin polyethylene bearings have caused concerns, including rim cracking and catastrophic implant failure with polyethylene thicknesses less than 5 millimeters. Recently, sequentially cross-linked and annealed polyethylene has been shown to reduce the wear rate significantly, compared to conventional ultra-high-molecular-weight polyethylene (UHMWPE) in vitro. The purpose of this study was to analyze the clinical and radiographic outcomes in a cohort of patients treated with sequentially cross-linked and annealed polyethylene bearings with a nominal thickness of 3.8 millimeters. Outcomes were compared to a similar cohort of patients who were treated with total hip arthroplasty during the same time period and utilizing the same polyethylene thickness of 5.8 millimeters or greater.

Materials and methods: We identified 50 patients (53 hips) who had a minimum 2-year clinical and radiographic follow-up after a standard total hip arthroplasty, performed with a thin, sequentially cross-linked and annealed polyethylene bearing surface. There were 15 males and 35 females, with a a mean age of 60 years (range, 16 to 93 years) and a mean body mass index of 28.6 kg/m² (range, 17.2 to 47.5 kg/m²). Overall survivorship was compared to a cohort of 50 patients (53 hips) treated with total hip arthroplasty during the same time period, utilizing the same polyethylene of 5.8 millimeters or greater thickness. Radiographic analysis of polyethylene wear was performed on a subset of 26 hips, using a previously validated two-dimensional computer-aided technique. Volumetric wear was calculated and subsequent annual volumetric and linear wear rates were derived for each patient in the study cohort. Additionally, radiographic analysis was performed to assess for any progressive radio-lucencies or malalignment.

Results: The overall survivorship of the study cohort was 100%, compared to a 96% survivorship in the comparison group (two failures due to infection). The mean Harris hip scores in the thin polyethylene cohort improved from 43 points (range, 10 to 67 points) pre-operatively to 91 points (range, 69 to 100 points) postoperatively. Upon radiographic review, no malalignment, radiolucencies, or polyethylene fracture was noted in the study cohort. The mean volumetric wear rate was 0.4122 mm³/year (range, 0.2311 to 0.7310 mm³/year), and the mean linear wear rate was 0.0004 mm/year (range, 0.0002 to 0.0007 mm/year) for the thin polyethylene group. The mean volumetric wear was 0.8839 mm³ (range, 0.4621 to 1.5839 mm³) for this cohort. Excellent cl

未标记:影响全髋关节置换术结果的两个重要问题是脱位和磨损,尽管临床结果很好。较大的股骨头成功地降低了脱位率;然而,人们担心随后使用更薄的聚乙烯衬垫,以及它们对磨损率的影响。从历史上看,聚乙烯薄轴承的高应力引起了人们的关注,包括边缘开裂和聚乙烯厚度小于5毫米的灾难性植入物失效。最近,与传统的超高分子量聚乙烯(UHMWPE)相比,连续交联和退火聚乙烯在体外试验中显著降低了磨损率。本研究的目的是分析一组连续使用交联和退火聚乙烯轴承治疗的患者的临床和影像学结果,其标称厚度为3.8毫米。结果与在同一时间段内接受全髋关节置换术的患者进行了比较,这些患者使用相同的聚乙烯厚度为5.8毫米或更大。材料和方法:我们确定了50例患者(53髋),他们在标准全髋关节置换术后进行了至少2年的临床和影像学随访,采用薄的、顺序交联的、退火的聚乙烯轴承表面。男性15例,女性35例,平均年龄60岁(16 ~ 93岁),平均体重指数28.6 kg/m²(17.2 ~ 47.5 kg/m²)。总生存率与同一时间段内接受全髋关节置换术的50例患者(53髋)的队列进行比较,使用相同的5.8毫米或更厚的聚乙烯。使用先前验证的二维计算机辅助技术,对26个髋关节进行了聚乙烯磨损的放射学分析。计算体积磨损,并得出研究队列中每个患者的年体积磨损率和线性磨损率。此外,进行放射学分析以评估任何进行性放射透光或对准不良。结果:研究队列的总生存率为100%,而对照组的生存率为96%(两例因感染而失败)。薄聚乙烯队列的Harris髋关节平均评分从术前的43分(范围,10至67分)提高到术后的91分(范围,69至100分)。在x线检查中,在研究队列中没有发现对准不良、放射透光或聚乙烯骨折。薄聚乙烯组的平均体积磨损率为0.4122 mm³/年(范围为0.2311 ~ 0.7310 mm³/年),平均线性磨损率为0.0004 mm/年(范围为0.0002 ~ 0.0007 mm/年)。该队列的平均体积磨损为0.8839 mm³(范围为0.4621至1.5839 mm³)。在全髋关节置换术中使用薄的、顺序交联的、退火的聚乙烯轴承(标称厚度为3.8毫米)治疗的患者具有良好的临床和影像学结果。我们还没有看到薄聚乙烯衬垫在这种制造过程中出现任何故障,这与之前报道的薄聚乙烯衬垫的结果形成鲜明对比。在相似时期,磨损率低于其他轴承表面。
{"title":"Early outcomes of sequentially cross-linked thin polyethylene liners with large diameter femoral heads in total hip arthroplasty.","authors":"Siraj A Sayeed,&nbsp;Michael A Mont,&nbsp;Christopher R Costa,&nbsp;Aaron J Johnson,&nbsp;Qais Naziri,&nbsp;Peter M Bonutti,&nbsp;Ronald E Delanois","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>Two important issues affecting the outcome of total hip arthroplasty have been dislocation and wear, despite excellent clinical results. Larger femoral heads have had success in decreasing dislocation rates; however, there are concerns regarding the subsequent use of thinner polyethylene liners, and their effects on wear rates. Historically, high stresses on thin polyethylene bearings have caused concerns, including rim cracking and catastrophic implant failure with polyethylene thicknesses less than 5 millimeters. Recently, sequentially cross-linked and annealed polyethylene has been shown to reduce the wear rate significantly, compared to conventional ultra-high-molecular-weight polyethylene (UHMWPE) in vitro. The purpose of this study was to analyze the clinical and radiographic outcomes in a cohort of patients treated with sequentially cross-linked and annealed polyethylene bearings with a nominal thickness of 3.8 millimeters. Outcomes were compared to a similar cohort of patients who were treated with total hip arthroplasty during the same time period and utilizing the same polyethylene thickness of 5.8 millimeters or greater.</p><p><strong>Materials and methods: </strong>We identified 50 patients (53 hips) who had a minimum 2-year clinical and radiographic follow-up after a standard total hip arthroplasty, performed with a thin, sequentially cross-linked and annealed polyethylene bearing surface. There were 15 males and 35 females, with a a mean age of 60 years (range, 16 to 93 years) and a mean body mass index of 28.6 kg/m² (range, 17.2 to 47.5 kg/m²). Overall survivorship was compared to a cohort of 50 patients (53 hips) treated with total hip arthroplasty during the same time period, utilizing the same polyethylene of 5.8 millimeters or greater thickness. Radiographic analysis of polyethylene wear was performed on a subset of 26 hips, using a previously validated two-dimensional computer-aided technique. Volumetric wear was calculated and subsequent annual volumetric and linear wear rates were derived for each patient in the study cohort. Additionally, radiographic analysis was performed to assess for any progressive radio-lucencies or malalignment.</p><p><strong>Results: </strong>The overall survivorship of the study cohort was 100%, compared to a 96% survivorship in the comparison group (two failures due to infection). The mean Harris hip scores in the thin polyethylene cohort improved from 43 points (range, 10 to 67 points) pre-operatively to 91 points (range, 69 to 100 points) postoperatively. Upon radiographic review, no malalignment, radiolucencies, or polyethylene fracture was noted in the study cohort. The mean volumetric wear rate was 0.4122 mm³/year (range, 0.2311 to 0.7310 mm³/year), and the mean linear wear rate was 0.0004 mm/year (range, 0.0002 to 0.0007 mm/year) for the thin polyethylene group. The mean volumetric wear was 0.8839 mm³ (range, 0.4621 to 1.5839 mm³) for this cohort. Excellent cl","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30095266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chondrosarcoma of the femur with histology-imaging correlation of tumor growth--preliminary observations concerning periosteal new bone formation and soft tissue extension. 股骨软骨肉瘤与肿瘤生长的组织学影像学相关性——关于骨膜新骨形成和软组织延伸的初步观察。
German C Steiner, Mark E Schweitzer, Samuel Kenan, Ibrahim F Abdelwahab

Unlabelled: The objective of this study was, in chondrosarcoma (CHS) of the femur, to evaluate by radiologic-pathologic correlation, the degree of tumor growth, cortical destruction, periosteal reaction, and soft tissue extension present.

Materials and methods: Eight cases of histologically proven CHS of the femur were studied. All cases were resected, evaluated histologically with coronal slabs, and compared with radiographs and magnetic resonance imaging (MRI) scans. In two resected specimens, the tumors were studied in more detail; along with coronal slabs, axial sections of the remaining anterior and posterior halves of both tumors were taken, and the bone specimens were X-rayed and examined histologically.

Results: CHS initially involved the medullary cavity and subsequently destroyed the cortex; first, by endosteal scalloping and, second, by subsequent invasion and destruction of the cortex. During this process, there was periosteal new bone formation (PNBF), with increased cortical thickness, the degree of which often correlated with the degree of cortical destruction. In the areas of cortical thickening of three cases, a "grey line" was seen on MRI that separated the cortex from the periosteal new bone; the line, in reality,is a space between the two structures. The presence of this line suggests that the tumor does not extend beyond the cortex. PNBF occurred in all cases and varied in thickness. It frequently developed independent of direct periosteal tumor involvement. The periosteum of one case contained porotic bone with interposed marrow fat, which was easily misinterpreted as tumor extension on MRI. Expansion and remodeling of the femoral diaphysis in CHS, with widening of the medullary cavity, is usually due to extensive cortical destruction with PNBF. Soft tissue extension was present in five cases and apparently occurred by two different mechanisms: direct tumor destruction of the cortex and periosteum, with extension into the soft tissues; and subtle MRI occult tumor permeation through the periosteum. As far as we know, a first literature histologic description of the thickened CHS periosteum also was accomplished.

Conclusion: PNBF is a common imaging manifestation of CHS of the femur, which correlated with the degree of cortical destruction. A grey line between the cortex and periosteum is an MRI finding described in this study and may facilitate the evaluation of periosteal thickening and tumor invasion in CHS. PNBF often occurs in the absence of direct periosteal involvement. Periosteal imaging abnormalities suggestive of tumor infiltration should be interpreted with caution on MRI, and early soft tissue extension in CHS may be difficult to determine on MRI.

未标记:本研究的目的是,在股骨软骨肉瘤(CHS)中,通过影像学和病理学的相关性来评估肿瘤生长、皮质破坏、骨膜反应和软组织延伸的程度。材料与方法:对8例经组织学证实的股骨CHS进行了研究。所有病例均被切除,用冠状板进行组织学评估,并与x线片和磁共振成像(MRI)扫描进行比较。在两个切除的标本中,对肿瘤进行了更详细的研究;除冠状面片外,对两个肿瘤剩余的前后半部分进行轴向切片,并对骨标本进行x光和组织学检查。结果:CHS最初累及髓腔,随后破坏皮层;首先是内层扇贝作用,其次是随后对皮层的侵袭和破坏。在此过程中,有骨膜新骨形成(PNBF),皮质厚度增加,其程度往往与皮质破坏程度相关。在3例皮质增厚的区域,MRI上看到一条“灰线”,将皮质与骨膜新生骨分开;实际上,这条线是两个结构之间的空间。这条线的存在表明肿瘤没有扩展到皮层以外。所有病例均出现PNBF,且厚度不同。它经常独立于骨膜肿瘤的直接累及而发展。1例骨膜含骨质疏松伴骨髓脂肪浸润,MRI易误诊为肿瘤扩展。CHS的股骨干扩张和重塑,伴髓腔变宽,通常是由于PNBF广泛的皮质破坏所致。5例患者出现软组织扩张,明显有两种不同的机制:肿瘤直接破坏皮层和骨膜,并扩展到软组织;MRI表现为隐蔽性肿瘤穿透骨膜。据我们所知,第一个文献组织学描述增厚CHS骨膜也完成。结论:PNBF是股骨CHS的常见影像学表现,与皮质破坏程度相关。皮层和骨膜之间的灰线是本研究描述的MRI发现,可能有助于评估CHS骨膜增厚和肿瘤侵袭。PNBF通常发生在没有直接累及骨膜的情况下。提示肿瘤浸润的骨膜成像异常在MRI上应谨慎解释,CHS的早期软组织扩张可能难以在MRI上确定。
{"title":"Chondrosarcoma of the femur with histology-imaging correlation of tumor growth--preliminary observations concerning periosteal new bone formation and soft tissue extension.","authors":"German C Steiner,&nbsp;Mark E Schweitzer,&nbsp;Samuel Kenan,&nbsp;Ibrahim F Abdelwahab","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>The objective of this study was, in chondrosarcoma (CHS) of the femur, to evaluate by radiologic-pathologic correlation, the degree of tumor growth, cortical destruction, periosteal reaction, and soft tissue extension present.</p><p><strong>Materials and methods: </strong>Eight cases of histologically proven CHS of the femur were studied. All cases were resected, evaluated histologically with coronal slabs, and compared with radiographs and magnetic resonance imaging (MRI) scans. In two resected specimens, the tumors were studied in more detail; along with coronal slabs, axial sections of the remaining anterior and posterior halves of both tumors were taken, and the bone specimens were X-rayed and examined histologically.</p><p><strong>Results: </strong>CHS initially involved the medullary cavity and subsequently destroyed the cortex; first, by endosteal scalloping and, second, by subsequent invasion and destruction of the cortex. During this process, there was periosteal new bone formation (PNBF), with increased cortical thickness, the degree of which often correlated with the degree of cortical destruction. In the areas of cortical thickening of three cases, a \"grey line\" was seen on MRI that separated the cortex from the periosteal new bone; the line, in reality,is a space between the two structures. The presence of this line suggests that the tumor does not extend beyond the cortex. PNBF occurred in all cases and varied in thickness. It frequently developed independent of direct periosteal tumor involvement. The periosteum of one case contained porotic bone with interposed marrow fat, which was easily misinterpreted as tumor extension on MRI. Expansion and remodeling of the femoral diaphysis in CHS, with widening of the medullary cavity, is usually due to extensive cortical destruction with PNBF. Soft tissue extension was present in five cases and apparently occurred by two different mechanisms: direct tumor destruction of the cortex and periosteum, with extension into the soft tissues; and subtle MRI occult tumor permeation through the periosteum. As far as we know, a first literature histologic description of the thickened CHS periosteum also was accomplished.</p><p><strong>Conclusion: </strong>PNBF is a common imaging manifestation of CHS of the femur, which correlated with the degree of cortical destruction. A grey line between the cortex and periosteum is an MRI finding described in this study and may facilitate the evaluation of periosteal thickening and tumor invasion in CHS. PNBF often occurs in the absence of direct periosteal involvement. Periosteal imaging abnormalities suggestive of tumor infiltration should be interpreted with caution on MRI, and early soft tissue extension in CHS may be difficult to determine on MRI.</p>","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30238700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hip resurfacing versus metal-on-metal total hip arthroplasty - are metal ion levels different? 髋关节表面置换与金属对金属全髋关节置换术-金属离子水平是否不同?
Paul R T Kuzyk, Michael Sellan, Michael Olsen, Emil H Schemitsch

A systematic review and meta-analysis of trials comparing hip resurfacing to metal-on-metal total hip arthroplasty was conducted to determine if there is a difference in serum metal ion levels in patients receiving these implants. EMBASE and MEDLINE databases were searched from inception to December 2010 for all trials involving the use of these devices. Eligibility for inclusion in the review were studies with 1. comparative trials that were both retrospective and prospective; 2. inclusion of a treatment arm receiving hip resurfacing; 3. inclusion of a treatment arm receiving metal-on-metal total hip arthroplasty; and 4. analysis of chromium and cobalt ions, or either, in patient serum or whole blood at a minimum of 1 year after implantation. The literature search identified 87 potential studies, of which 10 met the inclusion criteria. Pooled mean differences were calculated for serum cobalt and chromium ion levels. Mean differences for serum cobalt and chromium metal ions were not significantly different between hip resurfacing and metal-on-metal total hip arthroplasty patients, although there was a tendency for lower serum cobalt ion levels in patients receiving hip resurfacing. Larger prospective randomized trials are required to better substantiate a difference in metal ion levels occurring between these implants.

一项比较髋关节表面置换与金属对金属全髋关节置换术的系统综述和荟萃分析进行了,以确定接受这些植入物的患者血清金属离子水平是否存在差异。从开始到2010年12月,检索EMBASE和MEDLINE数据库,查找涉及使用这些设备的所有试验。有资格纳入本综述的研究有1。回顾性和前瞻性的比较试验;2. 纳入接受髋关节表面置换的治疗臂;3.纳入接受金属对金属全髋关节置换术的治疗臂;和4。植入后至少1年患者血清或全血中铬和钴离子的分析。文献检索发现87项潜在研究,其中10项符合纳入标准。计算血清钴和铬离子水平的合并平均差异。髋关节置换术和金属对金属全髋关节置换术患者血清钴和铬金属离子的平均差异无显著性差异,尽管髋关节置换术患者血清钴离子水平有降低的趋势。需要更大的前瞻性随机试验来更好地证实这些植入物之间金属离子水平的差异。
{"title":"Hip resurfacing versus metal-on-metal total hip arthroplasty - are metal ion levels different?","authors":"Paul R T Kuzyk,&nbsp;Michael Sellan,&nbsp;Michael Olsen,&nbsp;Emil H Schemitsch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A systematic review and meta-analysis of trials comparing hip resurfacing to metal-on-metal total hip arthroplasty was conducted to determine if there is a difference in serum metal ion levels in patients receiving these implants. EMBASE and MEDLINE databases were searched from inception to December 2010 for all trials involving the use of these devices. Eligibility for inclusion in the review were studies with 1. comparative trials that were both retrospective and prospective; 2. inclusion of a treatment arm receiving hip resurfacing; 3. inclusion of a treatment arm receiving metal-on-metal total hip arthroplasty; and 4. analysis of chromium and cobalt ions, or either, in patient serum or whole blood at a minimum of 1 year after implantation. The literature search identified 87 potential studies, of which 10 met the inclusion criteria. Pooled mean differences were calculated for serum cobalt and chromium ion levels. Mean differences for serum cobalt and chromium metal ions were not significantly different between hip resurfacing and metal-on-metal total hip arthroplasty patients, although there was a tendency for lower serum cobalt ion levels in patients receiving hip resurfacing. Larger prospective randomized trials are required to better substantiate a difference in metal ion levels occurring between these implants.</p>","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30240237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution of technique and indications for the Bernese periacetabular osteotomy. 伯尔尼髋臼周围截骨术技术和适应症的发展。
Michael Leunig, Reinhold Ganz

Acetabular dysplasia is among the most frequent causes of secondary osteoarthritis (OA) of the hip. While hip arthrolasty is a valid option in elderly patients, young and active patients are likely to outlive their implants and therefore may require a different approach. During the last 20 years, the emphasis of these osteotomies shifted from the femoral to the acetabular side, with the Bernese periacetabular osteotomy being one of the most frequently and successfully used techniques today. The procedure combines a polygonal juxta-articular osteotomy using a modified Smith-Peterson approach. During refinement of the technique, the principle osteotomy steps remained unchanged, while the soft-tissue dissection has been modified, in that the abductors are not detached from the iliac wing. Due to a better appreciation of hip deformities, other indications for this technique have continuously evolved over time.

髋臼发育不良是髋关节继发性骨关节炎(OA)最常见的原因之一。虽然髋关节置换术对老年患者是一种有效的选择,但年轻和活跃的患者可能比他们的植入物更长寿,因此可能需要不同的方法。在过去的20年里,这些截骨术的重点从股骨侧转移到髋臼侧,其中伯尔尼髋臼周围截骨术是当今最常用和最成功的技术之一。该手术采用改良的Smith-Peterson入路行多边形关节旁截骨术。在技术的改进过程中,截骨的主要步骤保持不变,而软组织剥离已被修改,因为外展肌未与髂翼分离。由于对髋关节畸形有了更好的认识,这项技术的其他适应症也随着时间的推移而不断发展。
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引用次数: 0
Osteoporosis - new treatments and updates. 骨质疏松症-新的治疗方法和更新。
Stephen Honig
{"title":"Osteoporosis - new treatments and updates.","authors":"Stephen Honig","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30237892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Bulletin of the NYU hospital for joint diseases
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