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Hypertonic solutions versus balanced crystalloids in severely burned patients: A systematic review and meta-analysis 严重烧伤患者的高渗溶液与平衡晶体:一项系统回顾和荟萃分析
Q3 Medicine Pub Date : 2026-02-01 DOI: 10.1016/j.burnso.2026.100444
Romario Rivera-Sanabria , María-Paula Benavides , Paola-Fernanda Orbes

Objective

To compare the effectiveness of hypertonic solutions versus balanced crystalloids on mortality in severely burned patients.

Material and methods

A systematic review was performed, following the PRISMA guidelines and the recommendations of the Cochrane Collaboration. We searched Medline, EMBASE, CENTRAL, and LILACS for studies comparing hypertonic solutions (HTS) and balanced crystalloids (BCS) for resuscitation in burn patients. Outcomes included mortality, urine output, and total fluid volume infused at 24 h.

Results

The review and analysis included six studies. Meta-analysis showed a significant disadvantage in survival for HTS versus BCS (OR for survival 0.42, 95 % CI 0.25–0.70, I2: 0 %), equating to a higher mortality risk with HTS. This finding persisted even though HTS reduced fluid requirements in patients with major burns (>30 % TBSA).

Conclusion

This meta-analysis suggests that the use of hypertonic solutions for resuscitation of severely burned patients is associated with a significantly higher risk of mortality compared to balanced crystalloids. This strong signal advocates a cautious clinical approach, favoring balanced crystalloids for resuscitation. However, more methodologically robust studies are needed to establish causality.
目的比较高渗液与平衡晶体液对严重烧伤患者死亡率的影响。材料和方法按照PRISMA指南和Cochrane协作网的建议进行系统评价。我们检索了Medline、EMBASE、CENTRAL和LILACS,以比较高渗溶液(HTS)和平衡晶体(BCS)在烧伤患者复苏中的作用。结果包括死亡率、尿量和24小时输注总液体体积。结果回顾和分析包括6项研究。荟萃分析显示,与BCS相比,HTS在生存方面存在显著劣势(OR为0.42,95% CI 0.25-0.70, I2: 0%),相当于HTS的死亡风险更高。即使HTS降低了严重烧伤患者(30% TBSA)的液体需要量,这一发现仍然存在。结论:本荟萃分析表明,与平衡晶体液相比,使用高渗溶液对严重烧伤患者进行复苏与明显更高的死亡风险相关。这个强烈的信号提倡谨慎的临床方法,倾向于平衡晶体的复苏。然而,需要更多方法学上可靠的研究来确定因果关系。
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引用次数: 0
Workforce-optimized traction method for lower limb burn surgery: Intraoperative verification 下肢烧伤手术劳动力优化牵引方法:术中验证
Q3 Medicine Pub Date : 2026-01-01 DOI: 10.1016/j.burnso.2025.100433
Kangdi Li , Jia Jia , Wu Jun , Yujie Cui , Xinfeng Huang , Jiaqi Xu

Background

Maintaining lower limb positioning is essential during burn debridement and grafting. Traditional manual traction or mechanical supports are labor-intensive and lack flexibility. We designed a novel ceiling-mounted traction system to optimize manpower use and improve surgical field exposure.

Methods

A ceiling-mounted elliptical track with an adjustable hook system was developed, allowing real-time adjustment of traction height (0–70 cm) and angle (0°–90°). Twenty-two patients (40 procedures) with deep partial- or full-thickness lower limb burns were.
randomized to an experimental group using the new device (n = 20) or a control group with manual traction (n = 20). Surgeon fatigue and surgical field exposure were assessed using a 10-point Visual Analog Scale (VAS).

Results

Compared with the control group, the experimental group reported significantly lower fatigue scores in medial, lateral, and posterior regions (p < 0.001), with no difference in the anterior region. Surgical field exposure satisfaction was also significantly higher in the experimental group for medial, lateral, and posterior regions (p < 0.001), with no difference in the anterior region.

Conclusion

The adjustable ceiling-mounted traction system enables rapid intraoperative repositioning, reduces surgeon fatigue, and enhances surgical field exposure, particularly in posterior lower limb areas. This method offers a feasible solution for manpower optimization in burn surgery.
背景:在烧伤清创和移植过程中,保持下肢定位是必不可少的。传统的人工牵引或机械支撑是劳动密集型的,缺乏灵活性。我们设计了一种新颖的吊顶式牵引系统,以优化人力使用并改善手术野暴露。方法研制一种可调吊钩悬挂式椭圆履带,可实时调节牵引高度(0 ~ 70 cm)和牵引角度(0°~ 90°)。22例(40次手术)下肢深度部分或全层烧伤。随机分为使用新装置的实验组(n = 20)和手动牵引的对照组(n = 20)。外科医生疲劳和手术视野暴露采用10分视觉模拟量表(VAS)进行评估。结果与对照组相比,实验组在内侧、外侧和后部区域的疲劳评分显著降低(p < 0.001),而在前部区域无差异。实验组在内侧、外侧和后部区域的手术野暴露满意度也显著更高(p < 0.001),而在前部区域没有差异。结论可调节顶置牵引系统可实现术中快速复位,减少外科医生疲劳,增加手术视野暴露,尤其是下肢后区。该方法为烧伤手术人力优化提供了可行的解决方案。
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引用次数: 0
Validation of the revised Baux score to predict mortality and formulation of a new model for burns mortality in Southeast Asian patients 修订后的Baux评分预测死亡率的有效性和东南亚患者烧伤死亡率新模型的制定
Q3 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.burnso.2025.100441
Michelle Hui Chin NEO , Claire Marie SHRESTHA , Li Xin Hannah CHEANG , Hui Chai FONG

Background

The Revised Baux (rBaux) Score is used to predict mortality in burn patients but has reduced accuracy at extremes of age and does not account for comorbidities – factors relevant in an ageing population. This study assessed rBaux mortality thresholds for adult burn patients and formulates a burn mortality model for Southeast Asian patients that includes comorbidities.

Materials and methods

We conducted a retrospective analysis of 720 adult admissions to the Burns Unit at a Southeast Asian tertiary unit from January 2019 to December 2023. After excluding patients with Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome, data from 649 patients on demographics, Total Body Surface Area (TBSA), inhalation injury, and Charlson Comorbidity Index (CCI) were analysed to identify mortality predictors, forming the basis of a new model.

Results

Of the 649 patients, 22 (3.39 %) died. Mortality was associated with higher age (median 53 vs. 42 years, p = 0.025), larger TBSA (73.5 % vs. 4.5 %, p < 0.001), inhalation injury (77.3 % vs. 33.5 %, p < 0.001), and higher CCI (2.5 vs. 0, p < 0.015). Predictive mortality thresholds were identified using rBaux, at 100 %, 75 %, and 50 % with scores of 159, 139, and 128, respectively. Multivariate analysis confirmed age, TBSA (in increments of 10 %)and Chronic Heart Failure (CHF) as independent predictors. Hence producing a new model with the following predictors: age, TBSA (in increments of 10 %), inhalation injury and Chronic Heart Failure (CHF). This new model had a Hosmer-Lemeshow. p-value of 0.77 and ROC area of 0.97, indicating excellent fit.

Conclusions

This model improves burn mortality predictions for Southeast Asian adults by incorporating comorbidities like CHF. Although more complex than rBaux, it offers better patient management potential, meriting further regional validation.
修订后的Baux (rBaux)评分用于预测烧伤患者的死亡率,但在极端年龄时准确性降低,并且不能考虑合并症——与人口老龄化相关的因素。本研究评估了成人烧伤患者的rBaux死亡率阈值,并为东南亚患者制定了包括合并症在内的烧伤死亡率模型。材料和方法我们对2019年1月至2023年12月在东南亚一家三级医院烧伤科住院的720名成年人进行了回顾性分析。在排除中毒性表皮坏死松解和Stevens-Johnson综合征患者后,对649例患者的人口统计学数据、体表总面积(TBSA)、吸入性损伤和Charlson合并症指数(CCI)进行分析,以确定死亡率预测因素,形成新模型的基础。结果649例患者中,死亡22例(3.39%)。死亡率与较高的年龄(中位53比42岁,p = 0.025)、较大的TBSA(73.5%比4.5%,p < 0.001)、吸入性损伤(77.3%比33.5%,p < 0.001)和较高的CCI(2.5比0,p < 0.015)相关。使用rBaux确定预测死亡率阈值,分别为100%、75%和50%,评分分别为159、139和128。多变量分析证实,年龄、TBSA(以10%的增量)和慢性心力衰竭(CHF)是独立的预测因素。因此,建立了一个新的预测因子模型:年龄、TBSA(增量10%)、吸入性损伤和慢性心力衰竭(CHF)。这个新模型有一个霍斯默-莱梅索。p值为0.77,ROC面积为0.97,拟合良好。该模型通过纳入慢性心力衰竭等合并症,提高了东南亚成年人烧伤死亡率的预测。虽然比rBaux更复杂,但它提供了更好的患者管理潜力,值得进一步的区域验证。
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引用次数: 0
The unhoused burn patient: an unmet need for prevention, treatment, and recovery 无家可归的烧伤患者:未满足的预防、治疗和康复需求
Q3 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.burnso.2025.100440
Soman Sen , Jason Heard , Tina Palmieri , Kathleen Romanowski
Burn injuries among unhoused individuals are a growing public health concern, with unique challenges related to the environments in which unhoused people live and the limited access they have to preventive resources and healthcare. Experiencing homelessness is associated with higher rates of morbidity and mortality from burns due to environmental exposure, inadequate living conditions, and delayed medical intervention. This review will discuss the epidemiology, mechanisms of burn injury, outcomes after burn injury, the role of mental health, preventive strategies, and the social and economic issues that heighten the risk of burns in unhoused populations. The review will also delve into areas of advocacy and research to reduce the risk of burn injury and address areas of treatment and recovery for unhoused patients.
无家可归者的烧伤是一个日益严重的公共卫生问题,无家可归者的生活环境以及他们获得预防性资源和保健的机会有限,给他们带来了独特的挑战。由于环境暴露、生活条件不足和医疗干预延迟,无家可归与较高的烧伤发病率和死亡率有关。本文将讨论流行病学、烧伤机制、烧伤后的结果、心理健康的作用、预防策略以及增加无住房人群烧伤风险的社会和经济问题。该审查还将深入研究宣传和研究领域,以减少烧伤风险,并解决无家可归患者的治疗和康复问题。
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引用次数: 0
Assessment of patient handouts on burns created by burn surgeons compared to ChatGPT-4o 与chatgpt - 40相比,烧伤外科医生制作的烧伤患者讲义的评估
Q3 Medicine Pub Date : 2025-12-11 DOI: 10.1016/j.burnso.2025.100438
Huzaifah Khan , Mauz Asghar , Xi Ming Zhu , Shahriar Shahrokhi
Physicians often face time constraints that may impact the delivery of patient education. Large language models have illustrated promising results in patient education across various specialties. The present study’s aim was to investigate the quality and readability of ChatGPT- generated handouts on burns and compare these results to a published handout. We asked ChatGPT-4o to generate and regenerate patient handouts for seven topics regarding burns. These handouts, along with a patient handout with similar topics published by Hamilton Health Sciences, were assessed. The Quality of Generated Language Outputs for Patients (QGLOP) scale was used to assess handouts based on accuracy/comprehensiveness, bias, currency, and tone, where each domain was scored out of 4 for a total of 16. The Simple Measure of Gobbledygook (SMOG) score was calculated to assess handout readability. The threshold for statistical significance was set at p < 0.05. The mean QGLOP scores for the ChatGPT-4o generated handouts and the published handout did not significantly differ. The mean QGLOP scores between ChatGPT-4o and the published handout were not significantly different for accuracy, bias, currency, and tone. ChatGPT-4o had lower scores on the topic of skin care, but higher scores on coping with burns. The two groups did not significantly differ for any other topic. We found that ChatGPT could produce patient education handouts on burns with scores comparable to those of a patient handout published by a burn unit, suggesting that plastic surgeons would have a similar level of satisfaction for both groups.
医生经常面临时间限制,这可能会影响患者教育的交付。大型语言模型在不同专业的患者教育中显示出有希望的结果。本研究的目的是调查ChatGPT生成的烧伤讲义的质量和可读性,并将这些结果与已发表的讲义进行比较。我们要求chatgpt - 40生成和再生关于烧伤的七个主题的患者讲义。这些讲义,以及汉密尔顿健康科学出版的类似主题的患者讲义,都进行了评估。患者生成语言输出的质量(QGLOP)量表用于评估讲义的准确性/全面性,偏差,货币和语气,其中每个领域得分为4分,共16分。计算简单的官样文章(SMOG)分数来评估讲义的可读性。p <; 0.05为有统计学意义的阈值。chatgpt - 40生成的讲义和发布的讲义的平均QGLOP分数没有显著差异。chatgpt - 40和发表的讲义之间的平均QGLOP分数在准确性、偏差、货币和语气方面没有显着差异。chatgpt - 40在皮肤护理方面得分较低,但在应对烧伤方面得分较高。两组在其他话题上没有显著差异。我们发现ChatGPT可以制作烧伤患者教育讲义,其分数与烧伤部门发布的患者讲义相当,这表明整形外科医生对两组患者的满意度相似。
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引用次数: 0
Burn wound microbiology and antimicrobial resistance patterns in a tertiary care burn unit in Northeast India 烧伤创面微生物学和抗菌素耐药性模式在印度东北部三级护理烧伤单位
Q3 Medicine Pub Date : 2025-12-10 DOI: 10.1016/j.burnso.2025.100439
Parthapratim Dutta, Vehuto Puro, Thounaojam Jeffchand Luwang, Utpal Kumar Bordoloi

Background

Burn wounds are highly susceptible to microbial colonization, especially by multidrug-resistant organisms (MDROs), contributing significantly to morbidity in resource-limited settings. Understanding local microbial patterns is essential for guiding empirical antibiotic selection and infection control practices. This study investigated the temporal profile of bacterial colonization and antimicrobial resistance in burn wounds at a tertiary care center in Northeast India.

Methods

A prospective study of 100 burn patients was conducted over six months. Wound swabs were collected on admission (Day 0) and Day 7. Bacterial identification and antimicrobial susceptibility testing were performed using the VITEK®2 system, interpreted per CLSI guidelines. Clinical infection was defined based on standard signs correlated with culture results.

Results

Bacterial growth increased from 25% on Day 0 to 91% on Day 7. Early cultures showed predominance of Staphylococcus aureus, whereas Day 7 cultures revealed a shift toward Gram-negative organisms, mainly Pseudomonas aeruginosa (36%) and Acinetobacter baumannii (16%). More than 70% of Gram-negative isolates exhibited resistance to cephalosporins and fluoroquinolones. Clinical burn wound infection occurred in 23 patients (23%), most commonly due to MDR Pseudomonas. Carbapenem resistance was identified in a subset of Acinetobacter isolates.

Conclusion

Burn wound colonization in our center transitions rapidly toward MDR Gram-negative pathogens, reinforcing the need for updated local antibiograms, culture-guided therapy, and strengthened infection prevention strategies. Focused antimicrobial stewardship and improved wound care workflows are essential to reducing infection-related complications.
背景:烧伤创面极易受到微生物定植的影响,尤其是耐多药生物(mdro),这在资源有限的环境中是导致发病率的重要因素。了解当地微生物模式对于指导经验性抗生素选择和感染控制实践至关重要。本研究调查了印度东北部一家三级护理中心烧伤创面细菌定植和抗菌药物耐药性的时间概况。方法对100例烧伤患者进行为期6个月的前瞻性研究。入院时(第0天)和第7天收集伤口拭子。使用VITEK®2系统进行细菌鉴定和抗菌药敏试验,按照CLSI指南进行解释。根据与培养结果相关的标准体征来确定临床感染。结果细菌生长从第0天的25%增加到第7天的91%。早期培养显示金黄色葡萄球菌占优势,而第7天的培养显示革兰氏阴性菌的转变,主要是铜绿假单胞菌(36%)和鲍曼不动杆菌(16%)。超过70%的革兰氏阴性分离株对头孢菌素和氟喹诺酮类药物耐药。临床烧伤创面感染23例(23%),最常见的原因是耐多药假单胞菌。在分离的不动杆菌中发现了碳青霉烯类耐药。结论本中心烧伤创面定植迅速向耐多药革兰氏阴性病原菌过渡,需要更新局部抗生素谱,培养引导治疗,加强感染预防策略。重点抗菌药物管理和改进伤口护理工作流程对于减少感染相关并发症至关重要。
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引用次数: 0
Total burn mortalities in Brazil: 10 years study 巴西烧伤总死亡率:10年研究
Q3 Medicine Pub Date : 2025-12-06 DOI: 10.1016/j.burnso.2025.100437
Luiz Philipe Molina Vana , Derek Chaves Lopes , André Vinícius Martignago , Laura Pompermaier , Jose Adorno , Mauricio José Lopes Pereima , Fábio Ferreira Amorim , Edgar Merchán-Hamann , Sérgio Eduardo Soares Fernandes

Background

Brazil is a large country with a high incidence of burn injuries and socio-economic disparities among its states that affect access to burn care. However, Brazil does not have a national burn database, and most of the research on burns analyzes local burn units’ registries. This study aimed to assess burn-related pre- and in-hospital mortality in Brazil between 2010 and 2019 and to investigate its relationship with sociodemographic aspects.

Methods

We have performed a cross-sectional study using publicly available data. Two information systems were compared for data qualification, the Mortality Information System (SIM) and the Hospital Information System (SIH).

Results

Pre-hospital mortality depends on burn etiology, with a relative risk of an out-of-hospital death from electrical burns compared to thermal burns of 1.59 (95 % CI: 1.55–1.63). Among all burn deaths, 76.2 % occurred in males, with a statistical significance for all age groups (p < 0.001). Regions with the lowest demographic density in the country had areas with high mortality, with a difference of mean from 2.21 inhab/Km2 (median: 2.19) in municipalities with mortality ≥4/100,000inhab to 127 inhab/Km2 (median 27.8) in municipalities with mortality <4/100,000inhab (p < 0.001). The association between mortality and the socioeconomic variables studied was exactly the opposite between thermal and electrical causes. A mean difference of 0.61 (95 % CI: 0.55–0.68) in in-hospital mortality due to general burns per 100,000 inhabitants was observed between the SIM database (mean: 0.64/100,000 inhabitants) and the SIH database (mean: 0.03/100,000 inhabitants; p < 0.001).

Conclusions

Our findings demonstrate that studies related to burns must analyze thermal and electrical etiologies separately since they present different correlations with sociodemographic aspects. Also, SIH should not be used to estimate burn incidence or mortality, since it underreports data.
巴西是一个烧伤高发的大国,其各州之间的社会经济差异影响了获得烧伤护理的机会。然而,巴西没有一个全国性的烧伤数据库,大多数关于烧伤的研究分析了当地烧伤单位的登记情况。本研究旨在评估巴西2010年至2019年期间与烧伤相关的住院前和住院死亡率,并调查其与社会人口统计学方面的关系。方法我们使用公开数据进行了横断面研究。比较死亡率信息系统(SIM)和医院信息系统(SIH)两种信息系统的数据质量。院前死亡率取决于烧伤病因,与热烧伤相比,电烧伤的院外死亡相对风险为1.59 (95% CI: 1.55-1.63)。在所有烧伤死亡中,76.2%发生在男性中,所有年龄组的差异均有统计学意义(p < 0.001)。全国人口密度最低的地区也有死亡率高的地区,死亡率≥4/10万居民的城市死亡率为2.21居民/平方公里(中位数为2.19),而死亡率≥4/10万居民的城市死亡率为127居民/平方公里(中位数为27.8)(p < 0.001)。死亡率与所研究的社会经济变量之间的关系与热因素和电因素之间的关系完全相反。在SIM数据库(平均值:0.64/10万居民)和SIH数据库(平均值:0.03/10万居民;p < 0.001)之间,观察到每10万居民因全身烧伤住院死亡率的平均差异为0.61 (95% CI: 0.55-0.68)。结论我们的研究结果表明,与烧伤相关的研究必须分别分析热病因和电病因,因为它们与社会人口统计学方面存在不同的相关性。此外,SIH不应用于估计烧伤发生率或死亡率,因为它低估了数据。
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引用次数: 0
Evaluation of the quality of m-Health applications in burns using the mobile app rating scale (MARS): A systematic review 使用移动应用程序评级量表(MARS)评估烧伤移动健康应用程序的质量:一项系统综述
Q3 Medicine Pub Date : 2025-11-28 DOI: 10.1016/j.burnso.2025.100436
Shahla Faramarzi , Sara Hashemi , Laya Rahmani Pirouz , Kimia Ashrafpour , Azita Yazdani , Leila Erfannia

Background

As mobile phone users and smart phone penetration grow, the healthcare sector utilizes mobile apps to enhance health management, particularly in the case of burns.

Purpose

The purpose of this research is to evaluate the quality of m-Health apps available in the field of burns in Persian-English language for the Android operating system.

Methods

A systematic search for burn-related apps was conducted on three mobile app stores (Google Play, Cafe Bazaar, and Myket) from February 11 to February 21, 2024. The search utilized English terms like “burn”, “burns”, “thermal”, as well as Persian keywords equivalent in meaning to “burn”. The selected apps underwent independent evaluation using the Mobile App Rating Scale (MARS).

Results

A total of 4172 apps were found. Then, by removing the duplicate apps, and based on the inclusion and exclusion criteria and after a complete review of the content, six apps entered the final stage of quality evaluation. Among the reviewed apps, two types of apps were identified: calculators, information apps. Based on the MARS scale, the functionality domain received the highest mean score of 4.75, whereas the aesthetics, information, and engagement domains scored lower, with mean scores of 3.27, 3.18, and 3.16, respectively.

Conclusion

The study found that the studied apps generally exhibited good functionality quality, and in terms of engagement, aesthetics, and information, they possessed acceptable quality, potentially improving digital health services for burns.
随着移动电话用户和智能手机普及率的增长,医疗保健部门利用移动应用程序来加强健康管理,特别是在烧伤的情况下。目的本研究的目的是评估在烧伤领域可用的移动健康应用程序的质量,在波斯语-英语Android操作系统。方法于2024年2月11日至2月21日在b谷歌Play、Cafe Bazaar和Myket三个移动应用商店系统搜索烧伤相关应用。搜索使用了“燃烧”、“烧伤”、“热”等英语词汇,以及与“燃烧”意思相同的波斯语关键词。选定的应用程序使用移动应用评级量表(MARS)进行独立评估。结果共发现应用程序4172个。然后,通过删除重复的应用程序,并根据纳入和排除标准,在对内容进行完整审查后,六个应用程序进入了质量评估的最后阶段。在被审查的应用程序中,确定了两种类型的应用程序:计算器和信息应用程序。根据MARS量表,功能领域的平均得分最高,为4.75分,而美学、信息和参与领域的平均得分较低,分别为3.27、3.18和3.16分。研究发现,所研究的应用程序总体上表现出良好的功能质量,在用户粘性、美观性和信息方面,它们具有可接受的质量,有可能改善烧伤的数字健康服务。
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引用次数: 0
12 Years of ablative fractional CO2 laser Practice: Logistics, lessons and evolving model of care 12年烧蚀分数CO2激光实践:后勤,经验教训和不断发展的护理模式
Q3 Medicine Pub Date : 2025-11-23 DOI: 10.1016/j.burnso.2025.100435
Natalia Ziolkowski , Fiona M. Wood , Suzanne Rea , Inge Spronk , Dale W. Edgar , Helen Douglas

Introduction

Ablative fractional CO2 lasers (AFCO2L) have been shown to improve burn hypertrophic scars significantly. In this paper we describe the journey of setting up the laser service for burns patients, considerations in patient selection, treatment algorithms, and lessons learned.

Methods

This study is a retrospective cohort study including all patients who received AFCO2L at the Western Australian (WA) Statewide Adult Burn Unit since the start of the program in 2013–2024. Descriptive statistics present the number, timing and settings of AFCO2L events, as well as patient, injury, and treatment characteristics. Further, the profile of patients who underwent laser treatment was compared to those who did not, during the study period.

Results

Since the introduction of the AFCO2L, a total of 4005 laser sessions involving 837 burns patients has been completed in WA. The majority were performed as an outpatient (66 %), with the proportion and total numbers increasing with time to 2021. Compared to those not receiving laser for their scars, AFCO2L was more likely applied to younger (p < 0.0001), female (p < 0.0001) patients with higher %TBSA burns (p < 0.0001) involving multiple anatomic areas (p = 0.001), more often requiring surgery (p < 0.0001) and longer times to heal (p < 0.0001). In 2013, 100 % of all lasers were provided as an inpatient, under general anesthetic with an average age of scar > 5000 days. By 2023/4, only 18 % required an inpatient stay and the average age of scar was 111 days.

Conclusions

The SABU team evolved AFCO2L therapy into the model of care over time to achieve earlier, more equitable delivery of laser treatments to 80 % of patients as outpatients, supported by extensive multidisciplinary team involvement.
烧蚀分数CO2激光(AFCO2L)已被证明可以显著改善烧伤增生性疤痕。在本文中,我们描述了为烧伤患者建立激光服务的历程,患者选择的考虑因素,治疗算法和经验教训。方法:本研究是一项回顾性队列研究,包括自2013-2024年该项目开始以来在西澳大利亚州(WA)全州成人烧伤科接受AFCO2L治疗的所有患者。描述性统计显示AFCO2L事件的数量、时间和设置,以及患者、损伤和治疗特征。此外,在研究期间,接受激光治疗的患者与未接受激光治疗的患者进行了比较。结果自引进AFCO2L以来,西澳共完成4005次激光治疗,涉及837例烧伤患者。大多数是作为门诊进行的(66%),比例和总数随着时间的推移而增加,直到2021年。与那些没有接受激光治疗疤痕的患者相比,AFCO2L更可能应用于年轻(p < 0.0001),女性(p < 0.0001)患者,TBSA烧伤比例较高(p < 0.0001),涉及多个解剖区域(p = 0.001),更经常需要手术(p < 0.0001),愈合时间更长(p < 0.0001)。2013年,100%的激光都是作为住院患者提供的,在全身麻醉下,平均疤痕年龄为5000天。到2023/4年,只有18%的人需要住院治疗,疤痕的平均年龄为111天。随着时间的推移,SABU团队将AFCO2L治疗发展成为一种护理模式,在广泛的多学科团队参与的支持下,为80%的门诊患者提供更早、更公平的激光治疗。
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引用次数: 0
Life-threatening drug-induced type B lactic acidosis & serotonin syndrome occurring simultaneously in a major burn patient: a case report 严重烧伤患者同时发生危及生命的药物致B型乳酸酸中毒和血清素综合征1例报告
Q3 Medicine Pub Date : 2025-11-01 DOI: 10.1016/j.burnso.2025.100430
Radwan Safa, Simon Myers
We present a unique case of hyperthermia and lactic acidosis in a patient with massive burn injury occurring after the administration of Linezolid. These acute and rapidly progressive symptoms were attributed to separate; rare adverse effects associated with linezolid. Treatment focused on aggressive cooling measures, discontinuation of offending agents, and hemodynamic and respiratory support. Hyperthermia and lactic acidosis resolved quickly after initiation of therapy. Unfortunately, the patient never recovered normal mental status for the remainder of his prolonged ICU stay. He underwent surgical tracheostomy and remained bedbound with minimal movement or interactions and was discharged to a long term facility.
我们提出了一个独特的情况下,热疗和乳酸性酸中毒的病人大面积烧伤后发生的管理利奈唑胺。这些急性和迅速进展的症状归因于单独的;与利奈唑胺相关的罕见副作用。治疗的重点是积极的降温措施,停用不良药物,以及血液动力学和呼吸支持。热疗和乳酸性酸中毒在治疗开始后迅速消退。不幸的是,在他延长的ICU住院期间,患者从未恢复正常的精神状态。他接受了气管切开术手术,卧床不能活动或互动,并出院进入长期治疗机构。
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Burns open : an international open access journal for burn injuries
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