Burns open : an international open access journal for burn injuries最新文献_第5页

Early opioid use in acute severe burn injuries and long-term pain and quality of life 急性严重烧伤早期阿片类药物使用与长期疼痛和生活质量的关系

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-02-22 DOI: 10.1016/j.burnso.2025.100401

Tessa Garside , Lachlan Donaldson , Emily Fitzgerald , Bao Teng , Anthony Delaney

Introduction

Pain management in the intensive care unit (ICU) following severe burn injury, particularly the use of high dose opioid therapy, may contribute to the development of long-term pain and impact long term health-related quality of life. This study aims to describe the analgesic management and long-term self-rated health-related quality of life, including functional, psychological and pain outcomes, in patients admitted to ICU with a major burn injury.

Methods

This was a retrospective analysis of prospectively collected data. All patients who were admitted to a tertiary referral intensive care unit with burns ≥20 % of total body surface area (TBSA) and survived to hospital discharge were included. Data relating to the severity of injury and analgesia management were collected for each patient. Patients completed follow up with the EQ-5D-5L questionnaire at 6- and 12-months post burn injury.

Results

84 patients were included. Seventy eight percent of patients reported long term issues with pain at 12 month follow up. Seventy-four percent of patients reported issues at 12 months with usual activities and 78 % reported issues with anxiety and depression. The mean dose of opioids (oral morphine equivalent dosing) prescribed to patients who reported issues with pain was not significantly different to those who did not report issues with pain at long term follow up (5079 (SD 7006) mg vs 3599 (SD 3175) mg, p = 0.2).

Conclusions

Patients who suffer major burns requiring ICU admission have long term issues with pain/discomfort, mobility, usual activities, self-care, and anxiety and depression, that are greater than reported in the general burns population. The total dose of opioids given in the acute stage of injury do not seem to influence the prevalence of long-term pain/discomforts in burn patients.

重症监护病房（ICU）严重烧伤后的疼痛管理，特别是使用高剂量阿片类药物治疗，可能导致长期疼痛的发展，并影响长期与健康相关的生活质量。本研究旨在描述ICU重症烧伤患者的镇痛管理和长期自评健康相关生活质量，包括功能、心理和疼痛结局。方法回顾性分析前瞻性收集的资料。所有烧伤面积≥体表面积（TBSA） 20%并存活至出院的三级转诊重症监护病房患者均被纳入研究。收集每位患者的损伤严重程度和镇痛处理相关数据。患者在烧伤后6个月和12个月完成EQ-5D-5L问卷的随访。结果共纳入84例患者。在12个月的随访中，78%的患者报告了长期的疼痛问题。74%的患者在12个月时报告了正常活动的问题，78%的患者报告了焦虑和抑郁的问题。在长期随访中，报告疼痛问题的患者与没有报告疼痛问题的患者的平均阿片类药物剂量（口服吗啡当量剂量）没有显著差异(5079 （SD 7006) mg vs 3599 (SD 3175) mg, p = 0.2）。结论重症烧伤患者在疼痛/不适、活动能力、日常活动、自我护理、焦虑和抑郁等方面存在长期问题，这些问题比一般烧伤患者更严重。在损伤急性期给予阿片类药物的总剂量似乎不影响烧伤患者长期疼痛/不适的患病率。

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引用次数: 0

Utilization of Suprathel® in delayed surgical management of toxic epidermal necrolysis (TEN): A case report 应用Suprathel®延迟手术治疗中毒性表皮坏死松解症（TEN）： 1例报告

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-02-21 DOI: 10.1016/j.burnso.2025.100399

Isabella Lipkin , Michelle Hughes , W.B. Hughes

Given the lack of established practice guidelines for the management of cutaneous symptoms associated with toxic epidermal necrolysis, treatments range from various dressings to skin substitutes. The following report details a case of a 21-year-old male patient with this diagnosis who presented nine days after rash eruption from an outside hospital with no signs of healing. The patient was then successfully managed surgically eleven days after symptom onset with debridement of epidermal blisters and placement of Suprathel®. To our knowledge, this publication is the first to describe the potential of this synthetic skin substitute in promoting epidermal regeneration for delayed surgical management of toxic epidermal necrolysis.

由于缺乏与中毒性表皮坏死松解相关的皮肤症状管理的既定实践指南，治疗范围从各种敷料到皮肤替代品。以下报告详细介绍了一例21岁男性患者的诊断，他在医院外皮疹爆发9天后出现，没有愈合的迹象。在症状出现11天后，患者通过表皮水疱清创和放置Suprathel®成功地进行了手术治疗。据我们所知，该出版物首次描述了这种合成皮肤替代品在促进表皮再生方面的潜力，用于延迟手术治疗中毒性表皮坏死松解。

引用次数: 0

Pathophysiology and management of burn injury-induced pain 烧伤引起的疼痛的病理生理学和处理

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-02-19 DOI: 10.1016/j.burnso.2025.100396

Zerong You , Shubhika Jain , Shiqian Shen , Jianren Mao , J.A. Jeevendra Martyn

This review examines the pathophysiology and therapeutic management of burn injury-induced pain (BIP). Burn injury, occurring globally in about 11 million people, often induces the most intense pain, but its management remains suboptimal. The pain often persists even after complete wound healing and hospital discharge causing both long-term disability and neurological dysfunction. The fact that BIP persists well beyond the initial hospitalization is not well recognized and should be underscored as the pain involves even non-burned areas. The pathophysiology of the latter problem is poorly understood and needs further study. Opioids, the mainstay for moderate to severe pain relief after major burn injury, with time, have poor analgesic and serious side effects. Accurate assessment pain of BIP and its biology at different stages of treatment helps to provide effective treatments of the different etiological factors that cause BIP and their sequelae. Based on clinical and pre-clinical studies, we discuss the current knowledge on the underlying cellular and molecular mechanisms in the initiation and persistence of BIP during the acute phase and later phases of injury. Opioid receptor-mediated signaling changes per se and immune microglia responses in concert exaggerate nociceptive behavior. Both burn injury and opioids upregulate spinal NMDA receptor expression and microglia changes, which further exaggerate pain. BIP has inflammatory and neuropathic components. Pharmacological and non-pharmacological approaches currently available for management of BIP is discussed. Areas that need further study include the role of other central and peripheral factors in the exaggeration of pain well beyond wound healing. Novel non-opioid methods to rectify BIP is important to develop in view of the potential for opioid use disorder. The role of microbiome in chronic pain syndromes is an unexplored territory and its relevance to BIP needs further examination. Pruritus or itch, though very common and important in the pharmacotherapy of burns, the discussion of this topic is brief. Extensive review of this topic is beyond the scope of this review in view of the vast body of knowledge and varying and multiple treatment options.

本文综述了烧伤引起的疼痛（BIP）的病理生理学和治疗管理。全球约有1100万人发生烧伤，通常会引起最剧烈的疼痛，但其治疗方法仍不理想。这种疼痛甚至在伤口完全愈合出院后仍然存在，造成长期残疾和神经功能障碍。事实上，在最初的住院治疗之后，pip仍然存在，这一事实尚未得到很好的认识，应该强调，因为疼痛甚至涉及非烧伤区域。后一个问题的病理生理学知之甚少，需要进一步研究。阿片类药物是严重烧伤后缓解中重度疼痛的主要药物，但随着时间的推移，其镇痛性较差，副作用严重。准确评估不同治疗阶段的BIP疼痛及其生物学特性，有助于对引起BIP及其后遗症的不同病因提供有效的治疗。基于临床和临床前研究，我们讨论了当前关于急性期和后期损伤中启动和持续BIP的潜在细胞和分子机制的知识。阿片受体介导的信号改变本身和免疫小胶质细胞反应一致地夸大了伤害性行为。烧伤和阿片类药物均上调脊髓NMDA受体的表达和小胶质细胞的变化，从而进一步加重疼痛。BIP有炎症和神经性成分。讨论了目前可用于治疗BIP的药物和非药物方法。需要进一步研究的领域包括其他中枢和外周因素在伤口愈合之外的疼痛夸大中的作用。鉴于阿片类药物使用障碍的潜在可能性，开发新的非阿片类药物纠正BIP的方法非常重要。微生物组在慢性疼痛综合征中的作用是一个未开发的领域，其与BIP的相关性需要进一步研究。瘙痒或瘙痒，虽然在烧伤的药物治疗中非常常见和重要，但这个话题的讨论是简短的。鉴于大量的知识和多种多样的治疗方案，对这一主题的广泛审查超出了本审查的范围。

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引用次数: 0

The relationship between burn area and severity and length of stay in burn patients treated at the leading referral burn Centre in West Java, Indonesia 在印度尼西亚西爪哇主要转诊烧伤中心治疗的烧伤患者的烧伤面积与严重程度和住院时间之间的关系

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-02-19 DOI: 10.1016/j.burnso.2025.100397

Patricia Andini , Arif Tri Prasetyo , Lisa Y. Hasibuan , Hardisiswo Soedjana , Filla Reviyani Suryaningrat

Background

Burns are severe injuries that require intensive medical care and have a significant impact on patients’ healing and rehabilitation processes. The outcome of burn treatment is largely influenced by the length of hospital stay, which is primarily determined by the surface area and severity of the burns. This study aims to examine the relationship between the extent (≥20 % TBSA) and severity of burns with prolonged hospitalization (≥14 days) in burn patients at the Burn Unit of Dr. Hasan Sadikin General Hospital, Bandung, from January 2021 to December 2023.

Methods

This research is an observational analytical correlational study using a cross-sectional approach. The subjects were burn patients hospitalized in the Burn Unit of Dr. Hasan Sadikin General Hospital during the same period, with data collected from their medical records. Out of 195 cases, only 82 were deemed suitable for evaluation. Statistical analysis of the categorical data was performed using the Chi-square test.

Results

The results indicated a significant relationship between the extent of burns and the length of hospital stay in patients who showed improvement, with a p-value of 0.003 and an Odds Ratio (OR) of 6.111. A significant relationship was also found between the severity of burns and the length of stay, with a p-value of 0.025 and an OR of 3.667. However, no significant relationship was observed between the extent of burns and the length of stay in patients who did not survive.

Conclusion

This study reveals a significant relationship between the extent and severity of burns and the length of hospital stay in patients who showed improvement in the Burn Unit of Dr. Hasan Sadikin General Hospital from January 2021 to December 2023.

背景：烧伤是一种严重的损伤，需要密集的医疗护理，对患者的愈合和康复过程有重大影响。烧伤治疗的结果在很大程度上受住院时间的影响，住院时间主要取决于烧伤的面积和严重程度。本研究旨在研究2021年1月至2023年12月万隆哈桑·萨迪金综合医院烧伤科烧伤患者的烧伤程度（≥20% TBSA）与住院时间延长（≥14天）烧伤严重程度之间的关系。方法采用横断面方法进行观察性分析相关研究。研究对象是同一时期在哈桑·萨迪金综合医院烧伤科住院的烧伤患者，数据收集自他们的医疗记录。在195个案例中，只有82个被认为适合评估。分类资料的统计分析采用卡方检验。结果结果显示，好转患者的烧伤程度与住院时间有显著相关，p值为0.003，优势比（OR）为6.111。烧伤严重程度与住院时间之间也存在显著关系，p值为0.025，OR为3.667。然而，未观察到未存活患者的烧伤程度与住院时间之间的显著关系。结论：本研究揭示了2021年1月至2023年12月在哈桑·萨迪金综合医院烧伤科好转的患者的烧伤程度和严重程度与住院时间之间的显著关系。

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引用次数: 0

A novel approach to non-surgical management of deep second-degree perianal burn in an immobile patient using platelet-rich plasma: A case report 一种利用富血小板血浆非手术治疗固定患者深二度肛周烧伤的新方法：1例报告

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-02-11 DOI: 10.1016/j.burnso.2025.100395

Martynas Tamulevicius, Peter M. Vogt, Vincent Maerz

This case report presents a 24-year-old patient with severe mental and physical disabilities who sustained deep partial-thickness burns to the perianal and gluteal region. Conventional surgical interventions, such as skin grafting, were deemed unsuitable due to the high risk of infection and the patient’s non-compliance with specialized positioning. Instead, the innovative use of platelet-rich plasma (PRP) therapy was implemented, involving subdermal PRP injections and daily dressing changes. PRP, derived from the patient’s own blood, offers low immunogenicity and promotes wound healing by enhancing angiogenesis, modulating inflammation, and reducing oxidative stress. The patient showed significant wound healing and reepithelialization, avoiding the need for any surgery. This case highlights the efficacy of PRP in managing complex burn wounds and underscores the necessity for personalized treatment strategies, particularly for patients with significant comorbidities, where conventional methods may pose additional risks.

这个病例报告了一个24岁的病人严重的精神和身体残疾谁持续深部分厚度烧伤到肛周和臀区。传统的手术干预，如植皮，由于感染的高风险和患者不遵守专门的定位，被认为是不合适的。取而代之的是实施富血小板血浆（PRP）治疗的创新应用，包括皮下PRP注射和每日换药。PRP来源于患者自身血液，具有低免疫原性，通过促进血管生成、调节炎症和减少氧化应激来促进伤口愈合。患者表现出明显的伤口愈合和再上皮化，避免了任何手术的需要。该病例强调了PRP在处理复杂烧伤创面方面的疗效，并强调了个性化治疗策略的必要性，特别是对于有明显合并症的患者，传统方法可能会带来额外的风险。

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引用次数: 0

Successful recovery of 85% TBSA burns in a resource-limited Nigerian hospital without a burns ward or intensive care unit: A case report 尼日利亚一家资源有限的医院，在没有烧伤病房或重症监护病房的情况下，85% TBSA烧伤成功恢复：1例报告

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-01-28 DOI: 10.1016/j.burnso.2025.100394

Innih Asuekome Kadiri , Kolawole Olubunmi Ogundipe , Deborah Aanuoluwapo Oluwatuyi

Survival and death from major burns are important indicators of burn treatment quality. Most burn-related mortalities occur in low- and medium-income countries (LMICs), with Africa accounting for a significant portion. While advancements in burn management have resulted in improved survival rates in high-income countries (HICs), LMICs like Nigeria still face high mortality rates, with a lethal area (LA50) below 50% TBSA.

This case report presents the successful management of a patient with 85% TBSA burns at a resource-limited tertiary hospital in southwest Nigeria, which lacks a dedicated burns ward and an intensive care unit. It highlights the potential for favourable outcomes in resource-limited settings when the managing team is committed.

重大烧伤的生存和死亡是烧伤治疗质量的重要指标。大多数与烧伤有关的死亡发生在低收入和中等收入国家，其中非洲占很大一部分。虽然烧伤管理方面的进步提高了高收入国家（HICs）的存活率，但尼日利亚等中低收入国家仍然面临高死亡率，致死面积（LA50）低于TBSA的50%。本病例报告介绍了尼日利亚西南部一家资源有限的三级医院对一名85% TBSA烧伤患者的成功治疗，该医院缺乏专门的烧伤病房和重症监护病房。它强调了在资源有限的环境中，当管理团队做出承诺时，可能会产生有利的结果。

引用次数: 0

Third-degree nasal tip burn in a preterm infant treated with amniotic membrane (Case report) 羊膜治疗早产儿鼻尖三度烧伤1例（附1例报告）

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-01-28 DOI: 10.1016/j.burnso.2025.100393

Paula Andrea Pérez Franco , Sebastian Murcia Espino , María Paula Ruiz Díaz , Juan David Rodríguez Parra

Introduction

Non-fatal burns are a global health issue with a considerable impact on morbidity as well as aesthetic and functional sequelae. Facial burns in neonates are rare and often occur in hospital settings due to medical devices. Due to its regenerative potential, the amniotic membrane has been used as an alternative treatment for superficial and partial-thickness burns. This report documents the successful use of the amniotic membrane in treating a third-degree burn on the nasal tip of a preterm newborn.

Case presentation and results

A male newborn at 33 weeks of gestation was admitted to the neonatal care unit and presented with a third degree burn on the tip, right ala, and columella of the nose, secondary to the use of malfunction on the temperature modulator of a ventilation mask. Initially, the use of hydrogel and dressings with Fitostimoline applied on the injury helped to partially eliminate the necrotic tissue, and then an amniotic membrane was placed on the injury. The 8-month follow-up showed adequate epithelialization without nasal collapse and a satisfactory aesthetic outcome were observed, although there was a slight loss of nasal tip projection.

Discussion

This case report demonstrates the effectiveness of the amniotic membrane in the healing process of nasal burns in neonates by improving wound healing and contributing to fibrosis reduction, due to its richness in growth factors and cytokines. Its anti-inflammatory and bacteriostatic effects contribute to pain control and reduce microbial proliferation, optimizing aesthetic outcomes. In combination with other dressings, the amniotic membrane promotes neovascularization and epithelialization preventing significant deformities.

Conclusion

The amniotic membrane is an effective alternative for treating neonatal facial burns, minimizing tissue damage and preserving nasal anatomy. This case report results highlight the importance of a multidisciplinary approach in treating facial burns, integrating surgical techniques and advanced wound care technologies to achieve adequate functional and aesthetic outcomes. However, long-term follow-up will establish the need for additional procedures and the evolution of the nasal anatomy.

非致死性烧伤是一个全球性的健康问题，对发病率以及美学和功能后遗症有相当大的影响。新生儿面部烧伤是罕见的，往往发生在医院设置由于医疗设备。由于其再生潜力，羊膜已被用作治疗浅表和部分厚度烧伤的替代方法。本报告记录了羊膜在治疗早产儿鼻尖三度烧伤中的成功应用。病例介绍和结果1例妊娠33周的男婴被新生儿护理病房收治，其鼻尖、右翼和鼻小柱三度烧伤，继发于通气面罩温度调节器使用故障。最初，在伤口上使用水凝胶和非托斯莫林敷料有助于部分消除坏死组织，然后在伤口上放置羊膜。8个月的随访显示，尽管鼻尖有轻微的突出，但上皮化良好，无鼻塌陷，美观效果令人满意。本病例报告证明了羊膜在新生儿鼻烧伤愈合过程中的有效性，由于其丰富的生长因子和细胞因子，羊膜通过促进伤口愈合和促进纤维化减少。其抗炎和抑菌作用有助于疼痛控制和减少微生物增殖，优化美学效果。与其他敷料结合，羊膜促进新生血管和上皮化，防止显著畸形。结论羊膜是治疗新生儿面部烧伤的有效替代材料，可减少组织损伤并保留鼻解剖结构。本病例报告的结果强调了多学科方法治疗面部烧伤的重要性，将外科技术和先进的伤口护理技术结合起来，以达到足够的功能和美学效果。然而，长期随访将确定需要额外的手术和鼻解剖的发展。

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引用次数: 0

A novel non-invasive treatment in deep burned patients who do not have consent to surgery 一种新颖的非侵入性治疗深度烧伤患者谁不同意手术

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-01-03 DOI: 10.1016/j.burnso.2024.100392

Seyed Hassan Tavoosi , Ali Ahmadabadi , Omid Yazarlou , Hossain Safari , Mahdi Kouhi Noghondar , Elaheh Emadi , Daryoush Hamidi Alamdari

One of the common traumatic injuries is burns. In deep burns, the standard of care (SOC) is surgical excision and skin grafting, still, some patients do not have consent to do the surgical procedure because of operation fear, comorbidity disorder, or contraindications for anesthesia. This study applied a novel repairing gel, also called SUPRAZ, to treat patients with deep burns to achieve outcomes similar to those of SOC. This gel was made from approved biochemical components involved in wound healing mechanisms. Over 18 months, from 2022 to 2024, this controlled single-arm clinical trial including 22 patients aged 4–80 years with deep partial or/and full thickness burns covering 0.5–12 % of their total body surface area was conducted. Despite the emphasis on surgery, these patients did not consent to do surgery. Therefore, repairing gel was applied topically on the burn area. Repairing gel time to heal the area of burns was 24.9 ± 8.5 (mean ± SD; days). The pain subsided after 10–15 min of use. During the 3–12 months follow-up of the patients, there were no signs of hypertrophic scars and keloids. The repairing gel was safe and can be used for patients who do not consent to surgery. Multicenter clinical trials are needed to substantiate the efficacy of repairing gel and achieving comparable long-term results to SOC in deep-burned patients. Trial registration: IRCT20191228045924N6.

最常见的创伤之一是烧伤。对于深度烧伤，标准的治疗方法是手术切除和植皮，但仍有部分患者因手术恐惧、合并症或麻醉禁忌症而不同意手术。本研究应用一种新型修复凝胶SUPRAZ治疗深度烧伤患者，达到与SOC相似的效果。这种凝胶是由经批准的参与伤口愈合机制的生化成分制成的。从2022年到2024年，这项为期18个月的对照单臂临床试验包括22名年龄4-80岁的患者，他们的深度部分或/和全层烧伤覆盖了他们体表面积的0.5 - 12%。尽管强调手术，但这些患者不同意做手术。因此，将修复凝胶局部涂抹在烧伤部位。修复凝胶时间为24.9±8.5(平均±SD；天)。使用10-15 min后疼痛消退。在3-12个月的随访中，患者没有出现增生性疤痕和瘢痕疙瘩的迹象。该修复凝胶是安全的，可用于不同意手术的患者。需要多中心临床试验来证实修复凝胶的有效性，并在深度烧伤患者中获得与SOC相当的长期效果。试验注册：IRCT20191228045924N6。

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引用次数: 0

Burns injury characteristics and outcomes at lautoka hospital, fiji 斐济劳托卡医院烧伤的特点和结局

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-01-01 DOI: 10.1016/j.burnso.2024.100384

Rahul Krishna Reddy , Arun Murari , Akhtar Ali , Ronal Kumar , Livai Lutunaika , Abhay Choudhari , Swastika Devi , Famiza Kulsum

Background

Burns injury are a global public health problem and one of the leading causes of morbidity and mortality. However, there is no published literature available from Lautoka Hospital in Fiji that assessed the characteristics and outcomes of burn patients.

Objective

The aim of this study was to explore sociodemographic and clinical characteristics, medical care and outcomes of burn injury patient at Lautoka Hospital in order to gain deeper insights into burns related issues and improve burns care at the hospital.

Method

A retrospective cross-sectional study was conducted between January 1st 2020 and June 30th 2024 at Lautoka Hospital in Fiji. Data were analysed using SPSS version 25. The association between independent variables and outcomes was assessed using Chi-square test.

Results

Study population included 267 patients predominately male (57 %). Majority of the patients (59 %) were aged below 10 years. Most of the burns occurred at home (92 %). A significant proportion of patients (64 %) had burns affecting multiple regions with the lower extremities being the most commonly affected area. Partial thickness burns were observed in 87.5 % of patients. The majority of patients (55 %) had a total body surface area (TBSA) < 10 % affected by burns. Normal saline (39 %) and Paracetamol (93 %) were most commonly used intravenous fluid and analgesic respectively. Most patients (93.5 %) underwent daily hydrotherapy while 26 % required surgical interventions. The median length of hospitalisation was 7.4 days. Wound infection occurred in 25 % of patients and the mortality rate was 10 %.

Conclusion

This study provides deeper insights into burn related issues in order to reduce the incidence and morbidity of burn injury, and improve care. This study is single centred and conducted retrospectively thus limiting exploration of additional associations. A multicentred prospective study is recommended.

背景：烧伤是一个全球性的公共卫生问题，也是导致发病和死亡的主要原因之一。然而，斐济Lautoka医院没有发表的文献评估烧伤患者的特征和结果。目的探讨Lautoka医院烧伤患者的社会人口学特征、临床特点、医疗护理及转诊情况，以期深入了解烧伤相关问题，提高医院烧伤护理水平。方法回顾性横断面研究于2020年1月1日至2024年6月30日在斐济Lautoka医院进行。数据分析采用SPSS 25。自变量与结果的相关性采用卡方检验。结果研究人群包括267例患者，以男性为主（57%）。大多数患者（59%）年龄在10岁以下。大多数烧伤发生在家中（92%）。相当比例的患者（64%）烧伤影响多个区域，下肢是最常见的影响区域。87.5%的患者出现部分厚度烧伤。大多数患者（55%）有总体表面积（TBSA） <；10%受烧伤影响。生理盐水（39%）和扑热息痛（93%）分别是最常用的静脉输液和止痛药。大多数患者（93.5%）接受每日水疗，26%需要手术干预。中位住院时间为7.4天。伤口感染发生率为25%，死亡率为10%。结论本研究为进一步了解烧伤相关问题，降低烧伤的发生率和发病率，提高护理水平提供了依据。这项研究是单中心的，回顾性的，因此限制了对其他关联的探索。建议进行多中心前瞻性研究。

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引用次数: 0

A perspective on the current state of smartphone-based mobile applications for scar assessment 基于智能手机的疤痕评估移动应用的现状

Q3 Medicine

Burns open : an international open access journal for burn injuries

Pub Date : 2025-01-01 DOI: 10.1016/j.burnso.2024.100389

Peter Moortgat , Jill Meirte , Mieke Anthonissen , Koen Maertens , Thibau Demarbaix , Ulrike Van Daele

Scars can have a significant impact on the physical and psychosocial well-being, so the assessment of scars is crucial for accurate diagnosis, monitoring, and treatment. Traditionally, these assessments required specialized, bulky equipment that needed a wired connection to computers, making these assessment tools less accessible and efficient. The increasing omnipresence of smartphones, equipped with high-resolution cameras and advanced sensors, presents an opportunity to address this gap by developing smartphone-based assessment tools. By providing an overview of the state of smartphone-based scar evaluation tools, this paper will highlight areas for future research and development.

After a comprehensive review and synthesis of existing literature on smartphone-based tools for scar assessment, the authors identified 11 devices which met the inclusion- and exclusion-criteria. Among the 11 devices, four assessed skin color, two focused on hydration, one measured elasticity, two evaluated texture, three measured temperature, and one assessed thickness. Nine devices were tested on human skin, and only two on scarred skin. Seven tools were evaluated for both validity and reliability, while four were only tested for validity. Five devices required an add-on or clip-on, while six utilized the smartphone’s built-in features. All devices demonstrated moderate to high feasibility for use in various settings and required specialized software for analysis.

The development of smartphone-based tools for scar assessment represents a significant advancement, offering accessible and portable solutions for both patients and clinicians. While only two scar-specific smartphone tools currently exist, applications, such as skin hydration and color measurement show promise for future integration. These tools have proven effective in assessing general skin characteristics but require further investigation of validity and reliability in a specific scar population. Moving forward, standardized protocols and enhanced imaging technologies, such as raw image formats, will be crucial for improving reliability.

疤痕会对身体和心理健康产生重大影响，因此对疤痕的评估对于准确诊断、监测和治疗至关重要。传统上，这些评估需要专门的、笨重的设备，这些设备需要与计算机有线连接，这使得这些评估工具的可访问性和效率降低。配备高分辨率摄像头和先进传感器的智能手机日益普及，为开发基于智能手机的评估工具解决这一差距提供了机会。通过概述基于智能手机的疤痕评估工具的现状，本文将重点介绍未来研究和发展的领域。在对基于智能手机的疤痕评估工具的现有文献进行全面回顾和综合后，作者确定了11种符合纳入和排除标准的设备。在11个设备中，4个评估肤色，2个专注于水合作用，1个测量弹性，2个评估质地，3个测量温度，1个评估厚度。9个设备在人体皮肤上进行了测试，只有两个在疤痕皮肤上进行了测试。七个工具评估了效度和信度，而四个只测试了效度。其中5款设备需要安装附件或夹式设备，6款使用智能手机的内置功能。所有的设备都显示出在各种设置中使用的中等到高度的可行性，并需要专门的软件进行分析。基于智能手机的疤痕评估工具的发展代表了一个重大的进步，为患者和临床医生提供了方便和便携的解决方案。虽然目前只有两种针对疤痕的智能手机工具，但皮肤水合作用和颜色测量等应用程序显示出未来集成的前景。这些工具已被证明在评估一般皮肤特征方面是有效的，但需要进一步研究特定疤痕人群的有效性和可靠性。展望未来，标准化协议和增强的成像技术，如原始图像格式，将是提高可靠性的关键。

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引用次数: 0