A. Arce-Esquivel, Gloria Duke, Jody K. Takemoto, C. A. Rizer, J. Ballard
Diminished vascular function has been reported to be common in patients with diabetic peripheral neuropathy (DPN) and acts as a major contributor to cardiovascular disease as well as lower limb complications. DPN is a consequence of diabetes-mediated impairment blood flow which leads to microvascular disturbances, which is best characterized as neuropathic pain. Foot pain due to DPN is one of the factors affecting walking ability. Infrared light therapy has been shown to be effective in reducing pain and increasing local circulation in a variety of painful conditions including neuropathy. This study aimed to determine the effects of infrared light therapy treatment on vascular function (i.e., microcirculation) and pain relief among patients with DPN. Nine patients (age: 74 ± 8.68 years) participated in this study. Infrared light therapy treatment was applied 3 times per week for 30 minutes per day, across 5 weeks. The light therapy intervention was performed using the Anodyne Therapy System (ATS). Before and after infrared light therapy treatment, vascular function [Digital Thermal Monitoring (DTM) of vascular reactivity] and pain assessment [Brief Pain Inventory-short form (BPI-SF) and short-form McGill Pain Questionnaire (SF-MPQ)] were evaluated. After the 5-week treatment, the vascular reactivity index (i.e., microvascular function) increased significantly by 25% from baseline (1.76 ± 0.13 to 2.20 ± 0.15, p < .05). In addition, the BPI-SF and SF-MPQ showed that pain decreased following light therapy. Our preliminary findings indicated that infrared light therapy promoted positive effects on microvascular function and pain relief in patients with DPN.
{"title":"Effects of Light Therapy on Vascular Function in Patients with Diabetic Peripheral Neuropathy","authors":"A. Arce-Esquivel, Gloria Duke, Jody K. Takemoto, C. A. Rizer, J. Ballard","doi":"10.33425/2639-8486.1026","DOIUrl":"https://doi.org/10.33425/2639-8486.1026","url":null,"abstract":"Diminished vascular function has been reported to be common in patients with diabetic peripheral neuropathy (DPN) and acts as a major contributor to cardiovascular disease as well as lower limb complications. DPN is a consequence of diabetes-mediated impairment blood flow which leads to microvascular disturbances, which is best characterized as neuropathic pain. Foot pain due to DPN is one of the factors affecting walking ability. Infrared light therapy has been shown to be effective in reducing pain and increasing local circulation in a variety of painful conditions including neuropathy. This study aimed to determine the effects of infrared light therapy treatment on vascular function (i.e., microcirculation) and pain relief among patients with DPN. Nine patients (age: 74 ± 8.68 years) participated in this study. Infrared light therapy treatment was applied 3 times per week for 30 minutes per day, across 5 weeks. The light therapy intervention was performed using the Anodyne Therapy System (ATS). Before and after infrared light therapy treatment, vascular function [Digital Thermal Monitoring (DTM) of vascular reactivity] and pain assessment [Brief Pain Inventory-short form (BPI-SF) and short-form McGill Pain Questionnaire (SF-MPQ)] were evaluated. After the 5-week treatment, the vascular reactivity index (i.e., microvascular function) increased significantly by 25% from baseline (1.76 ± 0.13 to 2.20 ± 0.15, p < .05). In addition, the BPI-SF and SF-MPQ showed that pain decreased following light therapy. Our preliminary findings indicated that infrared light therapy promoted positive effects on microvascular function and pain relief in patients with DPN.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41373803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dikshya Joshi, R. Timala, S. Pradhan, Jyotindra Sharma, Bijoy G Rajbanshi, N. Gautam, Raamesh Koirala, Apurb Sharma
{"title":"Prevalence of Coronary Artery Disease in Rheumatic Patients Undergoing Valve Surgeries in Nepal","authors":"Dikshya Joshi, R. Timala, S. Pradhan, Jyotindra Sharma, Bijoy G Rajbanshi, N. Gautam, Raamesh Koirala, Apurb Sharma","doi":"10.33425/2639-8486.1024","DOIUrl":"https://doi.org/10.33425/2639-8486.1024","url":null,"abstract":"","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49291317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Ho, C. Y, S. I, C. S., Sidibe N, Fofana Ch, Sogodogo A, Dakouo R, T. A., T. D, T. M, Maiga Ak, Doumbia Ct, M. I, Sanogo Km
Aim: This study aims to compare cardiovascular diseases direct costs for patients with and those without medical insurance. Methods: It was a prospective study from Mai 02 to August 31 2016 in the cardiology department of the UH GT. All outpatients aged 15 years and older, who came to visit, accepted to participate in the study and were involved. Direct costs (transport, consultation, labor tests and medicaments) were recorded for each patient at each visit. Data were inserted in a MS Access 2010 database and exported in SPSS 20 for analysis, comparing 2 groups (patients with and without medical insurance). Chi-2 and Fisher tests if applicable were used for statistical tests. Results: All patients seen in the study time (922 patients of whom 62.9% were female and 35.7% between 60-74 years ) were included. A proportion of 30.5% had medical insurance (281/922). Patients with diabetes, dyslipidemia and obesity were found among patients with medical insurance with respectively 47.5, 62.4 and 49.2%. Most frequent cardiovascular diseases among patients with medical insurance were high blood pressure without and with complications, acute coronary syndrome with respectively 36.2, 34.7 and 29.2%. Direct costs for patients with medical insurance were 1.06 to 1.77 times higher. Labor tests generated the highest costs. Direct costs for all cardiovascular diseases were higher for patients without medical insurance, up to 4 times for venous thrombo-embolic disease. Total costs were higher for patients with medical insurance. Conclusions: Direct costs for pathologies were higher for patients without medical insurance. Palpitation was the only pathology with direct costs higher for patients with medical insurance. Total costs for patients were higher for patients with medical insurance.
{"title":"Direct Cost of Cardiovascular Diseases in Cardiology Department of University Hospital Gabriel Touré (Uh Gt): Comparative Study Between Patients With and Without Medical Insurance","authors":"B. Ho, C. Y, S. I, C. S., Sidibe N, Fofana Ch, Sogodogo A, Dakouo R, T. A., T. D, T. M, Maiga Ak, Doumbia Ct, M. I, Sanogo Km","doi":"10.33425/2639-8486.1023","DOIUrl":"https://doi.org/10.33425/2639-8486.1023","url":null,"abstract":"Aim: This study aims to compare cardiovascular diseases direct costs for patients with and those without medical insurance. Methods: It was a prospective study from Mai 02 to August 31 2016 in the cardiology department of the UH GT. All outpatients aged 15 years and older, who came to visit, accepted to participate in the study and were involved. Direct costs (transport, consultation, labor tests and medicaments) were recorded for each patient at each visit. Data were inserted in a MS Access 2010 database and exported in SPSS 20 for analysis, comparing 2 groups (patients with and without medical insurance). Chi-2 and Fisher tests if applicable were used for statistical tests. Results: All patients seen in the study time (922 patients of whom 62.9% were female and 35.7% between 60-74 years ) were included. A proportion of 30.5% had medical insurance (281/922). Patients with diabetes, dyslipidemia and obesity were found among patients with medical insurance with respectively 47.5, 62.4 and 49.2%. Most frequent cardiovascular diseases among patients with medical insurance were high blood pressure without and with complications, acute coronary syndrome with respectively 36.2, 34.7 and 29.2%. Direct costs for patients with medical insurance were 1.06 to 1.77 times higher. Labor tests generated the highest costs. Direct costs for all cardiovascular diseases were higher for patients without medical insurance, up to 4 times for venous thrombo-embolic disease. Total costs were higher for patients with medical insurance. Conclusions: Direct costs for pathologies were higher for patients without medical insurance. Palpitation was the only pathology with direct costs higher for patients with medical insurance. Total costs for patients were higher for patients with medical insurance.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":"774 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69746695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamza Mohamed QabiL, A. Ramzy, M. Abdelmoneum, Khedr Ahmed Abd Elfattah
Abstract Background: After an acute coronary syndrome(ACS), patients continue to be at risk of major adverse cardiovascular events (MACE) despite the standard treatment. The risk of MACE may be secondary to thrombin,
{"title":"Assessing the Efficacy of Novel Oral Anticoagulants after Acute Coronary Syndrome","authors":"Hamza Mohamed QabiL, A. Ramzy, M. Abdelmoneum, Khedr Ahmed Abd Elfattah","doi":"10.7243/2052-4358-6-2","DOIUrl":"https://doi.org/10.7243/2052-4358-6-2","url":null,"abstract":"Abstract \u0000Background: After an acute coronary syndrome(ACS), patients continue to be at risk of major adverse cardiovascular events (MACE) despite the standard treatment. The risk of MACE may be secondary to thrombin,","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43285352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Menta, B. Ho, S. Coulibaly, D. Bagayogo, I. Sangare, D. Traoré, C. Thiam, Diall Ib, Y. Camara, S. Sidibé, M. Diakité, M. Konaté, K. Sanogo
Aim: To study the prevalence of peripartum cardiomyopathy (PPCM) in the cardiology department of Gabriel Touré University Hospital Center in Bamako. Material and Methods: This was a retrospective study, conducted over a 5-year period, from January 2011 to December 2015 and included all women hospitalized for either congestive heart failure or left-sided heart failure in the cardiology department of CHU Gabriel Touré. Results: From January 2011 to December 2015, 1933 patients were hospitalized in the cardiology department of CHU Gabriel Touré. Among them, 1154 women with heart failure, including 132 cases of peripartum cardiomyopathy, a prevalence of 6.8% of hospitalizations and 11.4% of women hospitalized for heart failure. Conclusion: Peripartum heart failure is a particular impaired maintenance due to its target population (reproductive age and chilbearing women) and its context. Its support requires close collaboration between several specialists. Its prevention can be considered if the management of certain factors such as anemia and malnutrition is effective in this target population during antenatal consultations. Good coverage of family planning could be beneficial for the prevention and management of recurrence.
目的:了解巴马科Gabriel tour大学医院中心心内科围生期心肌病(PPCM)的患病率。材料和方法:这是一项回顾性研究，从2011年1月到2015年12月进行了5年的研究，包括在CHU Gabriel tour心内科因充血性心力衰竭或左侧心力衰竭住院的所有女性。结果:2011年1月至2015年12月，我院心内科住院患者1933例。其中心力衰竭妇女1154例，其中围产期心肌病132例，住院率为6.8%，因心力衰竭住院的妇女占11.4%。结论:围产期心力衰竭是一种特殊的维持性受损疾病，这与它的目标人群(育龄妇女和育龄妇女)及其环境有关。它的支持需要几位专家之间的密切合作。如果在产前检查期间对这一目标人群中贫血和营养不良等某些因素的管理有效，就可以考虑预防这种疾病。良好的计划生育覆盖率有助于预防和管理复发。
{"title":"The Peri-Partum Cardiomyopathy in the Cardiology Department of Chu Gabriel Touré of Bamako","authors":"I. Menta, B. Ho, S. Coulibaly, D. Bagayogo, I. Sangare, D. Traoré, C. Thiam, Diall Ib, Y. Camara, S. Sidibé, M. Diakité, M. Konaté, K. Sanogo","doi":"10.33425/2639-8486.1015","DOIUrl":"https://doi.org/10.33425/2639-8486.1015","url":null,"abstract":"Aim: To study the prevalence of peripartum cardiomyopathy (PPCM) in the cardiology department of Gabriel Touré University Hospital Center in Bamako. Material and Methods: This was a retrospective study, conducted over a 5-year period, from January 2011 to December 2015 and included all women hospitalized for either congestive heart failure or left-sided heart failure in the cardiology department of CHU Gabriel Touré. Results: From January 2011 to December 2015, 1933 patients were hospitalized in the cardiology department of CHU Gabriel Touré. Among them, 1154 women with heart failure, including 132 cases of peripartum cardiomyopathy, a prevalence of 6.8% of hospitalizations and 11.4% of women hospitalized for heart failure. Conclusion: Peripartum heart failure is a particular impaired maintenance due to its target population (reproductive age and chilbearing women) and its context. Its support requires close collaboration between several specialists. Its prevention can be considered if the management of certain factors such as anemia and malnutrition is effective in this target population during antenatal consultations. Good coverage of family planning could be beneficial for the prevention and management of recurrence.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43064513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Coulibaly, S Diatema, O. Lawani, Hauhouot Attoungbre Ml
Background: Prior studies have shown a treatment gap in oral anticoagulant (OAC) use among patients with atrial fibrillation. It has been also shown that the lack of correct anticoagulation leads to greater risks of thromboembolic complications Methods: Using data collected beetween 2016 and 2017 we analysed the outcome of NVAF patients according to the nature and the quality of the antithrombotic treatment preccribed on an outpatients basis. Results: The mea nage of patients was 61.8 years with a male predominance of 52.7%. Dilated cardiomyopathies were the most prevalente underlying cardiopathies. The thromboembolic ris was high with a mean CHA2DS2VASC Score of 3. The hemorragic risk was low according to the HASBLED mean score of 0.8. Among 186 outpatients identified in our registry 135 received oral anticoagulant mainly VKA (132/135:97.8%), 28 received aspirin while 23 received no antithrombotic treatment. The one-year analysis revealed that patients well anticoagulated (TTR ≥65%) had the less mortality prevalence while those with TTR<65%, treated with aspirin or receving no antithrombotic treatment presented the highest mortality rate (p=0.018). Conclusion: Our work confirms the suboptimal use of oral anticoagualnt therapy in the management of NVAF and the necessity of a good oral anticoagulation therapy in the management of NVAF even in black patients thought to have lesser risk of thromboembolic complications.
{"title":"The One-Year Outcome of Patients with Non-valvular Atrial Fibrillation According to the Nature and Quality of the Antithrombotic Treatment Administered on an Outpatient Basis","authors":"I. Coulibaly, S Diatema, O. Lawani, Hauhouot Attoungbre Ml","doi":"10.33425/2639-8486.1021","DOIUrl":"https://doi.org/10.33425/2639-8486.1021","url":null,"abstract":"Background: Prior studies have shown a treatment gap in oral anticoagulant (OAC) use among patients with atrial fibrillation. It has been also shown that the lack of correct anticoagulation leads to greater risks of thromboembolic complications Methods: Using data collected beetween 2016 and 2017 we analysed the outcome of NVAF patients according to the nature and the quality of the antithrombotic treatment preccribed on an outpatients basis. Results: The mea nage of patients was 61.8 years with a male predominance of 52.7%. Dilated cardiomyopathies were the most prevalente underlying cardiopathies. The thromboembolic ris was high with a mean CHA2DS2VASC Score of 3. The hemorragic risk was low according to the HASBLED mean score of 0.8. Among 186 outpatients identified in our registry 135 received oral anticoagulant mainly VKA (132/135:97.8%), 28 received aspirin while 23 received no antithrombotic treatment. The one-year analysis revealed that patients well anticoagulated (TTR ≥65%) had the less mortality prevalence while those with TTR<65%, treated with aspirin or receving no antithrombotic treatment presented the highest mortality rate (p=0.018). Conclusion: Our work confirms the suboptimal use of oral anticoagualnt therapy in the management of NVAF and the necessity of a good oral anticoagulation therapy in the management of NVAF even in black patients thought to have lesser risk of thromboembolic complications.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43982643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Patted, S. Porwal, Sameer Ambar, Nikhil Basavanagowda, R. Bhise, M. Prasad, Vishwanath Hesarur, Vaibhav Patil
Introduction: Cancer is a major public health and economical concern. Chemotherapy induced LV Dysfunction hinders the applicability of these agents. Anthracycline chemotherapy plays a major role in many cancer treatments, especially breast cancer. Cardiotoxicity is a major concern in this group as it can have early onset or late onset, clinically apparent or subclinical. Echocardiography is the non-invasive technique of choice in the imaging of patients before, during and after undergoing chemotherapy. Speckle tracking echocardiography gives an objective and qualitative assessment of LV function. This study was done to assess the risk factors associated with chemotherapy induced LV Dysfunction along with the feasibility of 2D speckle tracking strain imaging. Methods: 54 consecutive patients above the age of 18 years diagnosed to have breast cancer from November 2015 to October 2016 were included in this study. The patients were further divided into LV Dysfunction group and Non LV Dysfunction group at the end of the follow up. The baseline clinical, echocardiographic parameters and follow up parameters were compared in the 2 groups. Results: Anthracycline induced LV Dysfunction was found in 14.8% of the study population. Advanced age, low BMI, Diabetes, advanced cancer stage, number of chemotherapy cycles were all found to be associated with increased risk of developing chemotherapy induced LV dysfunction. 2D strain imaging was helpful in early detection of LV Dysfunction in 25% of the LV Dysfunction group. Among the patients who had LV Dysfunction at the end of the chemotherapy regimen, 75% had persistent LV Dysfunction during follow-up where as 25% recovered their LV Function. Conclusion: Chemotherapy induced LV Dysfunction remains a major public health concern and it is not uncommon. The development of LV Dysfunction in this group of patients should be carefully monitored by 2D strain imaging as it can help in detection of early onset of LV Dysfunction.
{"title":"Use of 2D Strain Imaging for Detecting Left Ventricular Dysfunction in Patients Receiving Pre and Post Chemotherapy with Anthracyclines","authors":"S. Patted, S. Porwal, Sameer Ambar, Nikhil Basavanagowda, R. Bhise, M. Prasad, Vishwanath Hesarur, Vaibhav Patil","doi":"10.33425/2639-8486.1016","DOIUrl":"https://doi.org/10.33425/2639-8486.1016","url":null,"abstract":"Introduction: Cancer is a major public health and economical concern. Chemotherapy induced LV Dysfunction hinders the applicability of these agents. Anthracycline chemotherapy plays a major role in many cancer treatments, especially breast cancer. Cardiotoxicity is a major concern in this group as it can have early onset or late onset, clinically apparent or subclinical. Echocardiography is the non-invasive technique of choice in the imaging of patients before, during and after undergoing chemotherapy. Speckle tracking echocardiography gives an objective and qualitative assessment of LV function. This study was done to assess the risk factors associated with chemotherapy induced LV Dysfunction along with the feasibility of 2D speckle tracking strain imaging. Methods: 54 consecutive patients above the age of 18 years diagnosed to have breast cancer from November 2015 to October 2016 were included in this study. The patients were further divided into LV Dysfunction group and Non LV Dysfunction group at the end of the follow up. The baseline clinical, echocardiographic parameters and follow up parameters were compared in the 2 groups. Results: Anthracycline induced LV Dysfunction was found in 14.8% of the study population. Advanced age, low BMI, Diabetes, advanced cancer stage, number of chemotherapy cycles were all found to be associated with increased risk of developing chemotherapy induced LV dysfunction. 2D strain imaging was helpful in early detection of LV Dysfunction in 25% of the LV Dysfunction group. Among the patients who had LV Dysfunction at the end of the chemotherapy regimen, 75% had persistent LV Dysfunction during follow-up where as 25% recovered their LV Function. Conclusion: Chemotherapy induced LV Dysfunction remains a major public health concern and it is not uncommon. The development of LV Dysfunction in this group of patients should be carefully monitored by 2D strain imaging as it can help in detection of early onset of LV Dysfunction.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45954972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Inflammation characterizes atherothrombosis and the presence of inflammation at the site of the atherosclerotic lesion has a role in plaque formation and acute rupture. Previous studies demonstrated that elevated peripheral blood platelet count and a low peripheral blood lymphocyte count are associated with major adverse cardiovascular outcomes. Therefor we supposed that; platelet-lymphocyte ratio (PLR) may have a prognostic value in patients with NSTSEMI. Patents and Methods: 90 patients with NSTEMI were included in our study. Then Complete history was taken, General and local examination were done, Blood sample was taken for laboratory tests with especial interest to PLR, ECG, and bedside screening ECHO were done on admission. Lastly, Coronary angiography; SYNTAX (SX) score, TIMI flow and myocardial blush grade (MBG) were estimated. Results: After classified our study population (90 patients) into three groups: Group 1 (N = 55): EF ˃ 50%. Group 2 (N = 16): EF 40-50%. Group 3 (N = 19): EF ˂ 40%. There was highly statistically significant difference between three groups regarding platelets, lymphocytes and PLR (P<0.001). PLR >149.05 had statistically highly significant positive correlation with SX score and troponin (p<0.001), on the other hand PLR had statistically highly significant negative correlation with EF and MBG (p<0.001) and had statistically significant negative correlation with TIMI flow (p<0.05). Conclusion: PLR >149.05 was associated with LV systolic dysfunction with sensitivity and specificity 100% and 84.5%, respectively.
{"title":"The Prognostic Value of Platelet–lymphocyte Ratio (PLR) in Patients with Non ST Segment Elevation Myocardial Infarction (NSTEMI)","authors":"A. Shawky, H. Radwan","doi":"10.33425/2639-8486.1019","DOIUrl":"https://doi.org/10.33425/2639-8486.1019","url":null,"abstract":"Background: Inflammation characterizes atherothrombosis and the presence of inflammation at the site of the atherosclerotic lesion has a role in plaque formation and acute rupture. Previous studies demonstrated that elevated peripheral blood platelet count and a low peripheral blood lymphocyte count are associated with major adverse cardiovascular outcomes. Therefor we supposed that; platelet-lymphocyte ratio (PLR) may have a prognostic value in patients with NSTSEMI. Patents and Methods: 90 patients with NSTEMI were included in our study. Then Complete history was taken, General and local examination were done, Blood sample was taken for laboratory tests with especial interest to PLR, ECG, and bedside screening ECHO were done on admission. Lastly, Coronary angiography; SYNTAX (SX) score, TIMI flow and myocardial blush grade (MBG) were estimated. Results: After classified our study population (90 patients) into three groups: Group 1 (N = 55): EF ˃ 50%. Group 2 (N = 16): EF 40-50%. Group 3 (N = 19): EF ˂ 40%. There was highly statistically significant difference between three groups regarding platelets, lymphocytes and PLR (P<0.001). PLR >149.05 had statistically highly significant positive correlation with SX score and troponin (p<0.001), on the other hand PLR had statistically highly significant negative correlation with EF and MBG (p<0.001) and had statistically significant negative correlation with TIMI flow (p<0.05). Conclusion: PLR >149.05 was associated with LV systolic dysfunction with sensitivity and specificity 100% and 84.5%, respectively.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69746658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Implantable cardioverter defibrillators (ICDs) reduce the risk of sudden death in eligible patients. However, it is thought that there is a relationship between the ICD shocks and increased morbidity and mortality. In this study, we examined the relationship between ICD shocks and the CHA2DS2-VASc scoring, which has gained frequent use in predicting cardiac events recently. Material and Methods: Retrospective baseline characteristics and three-year follow-ups of patients with ICDs with appropriate indication were studied. Patients were divided into two groups: patients who have received ICD shock(s) and patients who have not received any ICD shock. These groups were compared for baseline characteristics and CHA2DS2-VASc scores. Results: CHA2DS2-VASc scores of heart failure (HF) patients in our study population were significantly higher than those who did not receive any shock within three years following the ICD implantation. The rate of appropriate or inappropriate ICD shocks was %16 in the HF patients implanted with ICD for primary prevention while it was %66 in patients implanted with ICD for secondary prevention. The incidence of atrial fibrillation was 68% in 37 patients who received inappropriate shock while it was 7% in those who did not receive inappropriate shock (those who received appropriate shocks or did not receive any shock) (p<0.001). Conclusion: In conclusion, this study demonstrated a relation between the CHA2DS2-VASc score and appropriate and inappropriate ICD shocks. The CHA2DS2-VASc score is a simple tool that may predict ICD shocks.
{"title":"Benefit of CHA2 DS2 -VASc Score in Predicting Implantable Cardioverter Defibrillator Shocks","authors":"S. Gunay, S. Seyis, Özge Kurmuş","doi":"10.33425/2639-8486.1020","DOIUrl":"https://doi.org/10.33425/2639-8486.1020","url":null,"abstract":"Introduction: Implantable cardioverter defibrillators (ICDs) reduce the risk of sudden death in eligible patients. However, it is thought that there is a relationship between the ICD shocks and increased morbidity and mortality. In this study, we examined the relationship between ICD shocks and the CHA2DS2-VASc scoring, which has gained frequent use in predicting cardiac events recently. Material and Methods: Retrospective baseline characteristics and three-year follow-ups of patients with ICDs with appropriate indication were studied. Patients were divided into two groups: patients who have received ICD shock(s) and patients who have not received any ICD shock. These groups were compared for baseline characteristics and CHA2DS2-VASc scores. Results: CHA2DS2-VASc scores of heart failure (HF) patients in our study population were significantly higher than those who did not receive any shock within three years following the ICD implantation. The rate of appropriate or inappropriate ICD shocks was %16 in the HF patients implanted with ICD for primary prevention while it was %66 in patients implanted with ICD for secondary prevention. The incidence of atrial fibrillation was 68% in 37 patients who received inappropriate shock while it was 7% in those who did not receive inappropriate shock (those who received appropriate shocks or did not receive any shock) (p<0.001). Conclusion: In conclusion, this study demonstrated a relation between the CHA2DS2-VASc score and appropriate and inappropriate ICD shocks. The CHA2DS2-VASc score is a simple tool that may predict ICD shocks.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45725818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Ho, S. I, C. Y, Sidibe N, C. S., T. D, C. Joseph, Dakouo R, Traoré A, Samaké S, Sogodogo A, S. S, Sidibé Lamine, M. I, Diall Ib, Sanogo Km
Aim: Estimate Cardiovascular Risk for Patients in the Outpatient Unit in UH GT using the WHO cholesterol free chart. Methods: A cross-sectional, descriptive and analytic study was performed from May 02 to September 02, 2016 in the UH GT outpatient unit. Involved patients were older 15 years and gave consent to participate in the study. All patients were interviewed, underwent physical examination and labor assessment. Cardiovascular risk was evaluated using the WHO chart, without cholesterol availability, with blood glucose, sex, smoking, age, systolic blood pressure (SBP). Data were recorded in an ACCESS 2010 database, processed in MS Excel 2010 and analyzed using SPSS software version 20. Results: 922 patients (62.9% female and 69.5% without health insurance) were seen. Risk factors in the sample were dominated by hypertension, diabetes, and physical inactivity. Patients with a risk <10% accounted for 83.4%. Sex and age range were significantly different from the level of risk. The most common pathologies did not differ statistically significantly from the estimated risk (p = 0.998). Conclusion: Since cholesterol dosing is not always available, a cardiovascular risk assessment using a method without cholesterol is a good alternative. Studies are needed to define the profile of patients in whom it is necessary to assess cholesterol level for the cardiovascular risk assessment.
{"title":"Cardiovascular Risk (CV) Assessment according to the WHO Cholesterol Free Chart in the Cardiology Department of University Hospital Gabriel Touré","authors":"B. Ho, S. I, C. Y, Sidibe N, C. S., T. D, C. Joseph, Dakouo R, Traoré A, Samaké S, Sogodogo A, S. S, Sidibé Lamine, M. I, Diall Ib, Sanogo Km","doi":"10.33425/2639-8486.1018","DOIUrl":"https://doi.org/10.33425/2639-8486.1018","url":null,"abstract":"Aim: Estimate Cardiovascular Risk for Patients in the Outpatient Unit in UH GT using the WHO cholesterol free chart. Methods: A cross-sectional, descriptive and analytic study was performed from May 02 to September 02, 2016 in the UH GT outpatient unit. Involved patients were older 15 years and gave consent to participate in the study. All patients were interviewed, underwent physical examination and labor assessment. Cardiovascular risk was evaluated using the WHO chart, without cholesterol availability, with blood glucose, sex, smoking, age, systolic blood pressure (SBP). Data were recorded in an ACCESS 2010 database, processed in MS Excel 2010 and analyzed using SPSS software version 20. Results: 922 patients (62.9% female and 69.5% without health insurance) were seen. Risk factors in the sample were dominated by hypertension, diabetes, and physical inactivity. Patients with a risk <10% accounted for 83.4%. Sex and age range were significantly different from the level of risk. The most common pathologies did not differ statistically significantly from the estimated risk (p = 0.998). Conclusion: Since cholesterol dosing is not always available, a cardiovascular risk assessment using a method without cholesterol is a good alternative. Studies are needed to define the profile of patients in whom it is necessary to assess cholesterol level for the cardiovascular risk assessment.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49570313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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