Cardiopulmonary physical therapy journal最新文献

Purpose: Despite the dramatic improvement in pulmonary function after lung transplantation, lung transplant recipients often have reduced physical function. The purpose of this study was to investigate the associations between physical function and a wide range of patient-level factors among lung transplant recipients to allow researchers and healthcare providers to identify and better understand contributors to poor physical function.

Methods: A cross-sectional study of lung transplant recipients enrolled in Lung Transplant Go (LTGO), a randomized, controlled trial evaluating the efficacy of a telerehabilitation behavioral exercise intervention on physical function. Data were collected at the time of study enrollment for physical function using 30-second sit-to-stand test (STS-30), and patient-level factors: discharge destination, time since transplant, hospital length of stay, participation in exercise program outside the study, comorbidities, psychological distress, and symptoms. Regression analysis was performed to identify the association between physical function and patient-level factors.

Results: A total of 72 lung transplant recipients with a mean age of 56 (13), 58% male, and 88% white, completed the STS-30. The bivariate analysis identified factors associated with STS-30, which are age, marital status, time since transplant, Questionnaire for Lung Transplant Patients' activity intolerance subscale, and psychological distress. Factors significantly predicted STS-30 using the regression analysis were age, time since transplant, and psychological distress (p< 0.05).

Conclusion: Age, time since lung transplantation, and psychological distress significantly predicted poor physical function. Interventions to prevent poor physical function post-lung transplantation should consider these factors. Research is needed to better understand patient-level factors on other physical function measures.

Background and purpose: Among individuals with diagnosed heart failure (HF), the impact of physical activity on systemic inflammation and risk of hospital admissions remains unclear. This study examines the associations between physical activity and 1) systemic inflammation measured through C-reactive protein (CRP) levels and 2) frequency of hospital admissions in those with HF.

Methods: We utilized data from the National Health and Nutrition Evaluation Survey in this observational cross-sectional study to include 377 community-dwelling adults with HF. Demographic, clinical, and functional variables were extracted from the data and included in the regression models as covariates during analysis. Associations between activity and hospital admissions were examined using Poisson regression. Multivariable logistic regression analysis was used for association between CRP and physical activity.

Results: We found a direct linear relationship between CRP levels and hospital admissions with higher levels of CRP significantly associated with greater number oof hospital admissions in HF (IRR = 1.18, p < 0.001). Similarly, participating in vigorous activity was significantly associated with decreased expected rate of hospital admissions (IRR = 0.38, p = 0.013 (C.I. = 0.18-0.80) and with a significant decrease in the CRP levels (B = -0.44, p = 0.018 (C.I. = -0.80 - -0.83).

Discussion: To our knowledge, this is the first study using population-level data to examine the association between physical activity level, systemic inflammation, and hospitalizations in individuals with HF.

Conclusions: The findings of this study demonstrate that irrespective of sex, engagement in physical activity at higher intensity levels is strongly associated with favorable health outcomes in older adults with HF.