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[Metabolic bariatric surgery as bridging to transplantation-Concepts and results]. [代谢减肥手术作为移植的桥梁-概念和结果]。
Pub Date : 2025-12-01 Epub Date: 2025-10-20 DOI: 10.1007/s00104-025-02391-z
Undine Gabriele Lange, Arne Dietrich

Background: Due to the generally increasing number of obese patients with obesity-associated comorbidities (e.g. type 2 diabetes mellitus and nonalcoholic fatty liver disease/steatohepatitis), they are increasingly becoming transplantation candidates; however, this patient cohort is more frequently affected by intraoperative and postoperative complications and poorer transplant outcome.

Objective: This article provides an overview of the indications, choice of procedure and outcome of bariatric surgery prior to solid organ transplantation.

Material and methods: The current literature was evaluated and discussed.

Results: Postoperative complications occur more frequently in bariatric patients with (terminal) organ dysfunction than without but the mortality remains low. On the other hand, these patients can be successfully transplanted significantly more often due to weight loss, with a better transplant outcome. In a not insignificant proportion of patients, the operation even leads to an improvement in the underlying disease, so that there is no longer an indication for listing. In the case of liver cirrhosis, bariatric surgery should only be performed in the compensated stage (Child-Pugh A and early B, no higher stage of portal hypertension). Sleeve gastrectomy and Roux-en‑Y gastric bypass are to be preferred. Multidisciplinary care at a center is particularly important in this patient group.

Discussion: Bariatric surgery as a bridging procedure to transplantation appears to be safe but data and evidence are limited due to low overall patient numbers and pending prospective randomized trials.

背景:由于肥胖患者与肥胖相关的合并症(如2型糖尿病和非酒精性脂肪肝/脂肪性肝炎)的数量普遍增加,他们越来越多地成为移植候选者;然而,这组患者更容易受到术中和术后并发症的影响,移植预后较差。目的:本文综述了实体器官移植前减肥手术的适应症、手术方法的选择和结果。材料和方法:对现有文献进行评价和讨论。结果:伴有(终末)器官功能障碍的肥胖患者术后并发症发生率高于无器官功能障碍的肥胖患者,但死亡率较低。另一方面,这些患者由于体重减轻,移植成功率明显提高,移植效果也较好。在相当比例的患者中,手术甚至导致了潜在疾病的改善,以至于不再有上市的指征。在肝硬化的情况下,减肥手术只应在代偿期(Child-Pugh A和早期B,不应进行门静脉高压症的更高阶段)进行。套管胃切除术和Roux-en - Y胃旁路是首选。中心的多学科护理对这一患者群体尤为重要。讨论:减肥手术作为移植的桥接手术似乎是安全的,但由于患者总人数较少和有待前瞻性随机试验,数据和证据有限。
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引用次数: 0
[Entrustable professional activities-A paradigm shift in the surgical training from quantity to quality]. 可信赖的专业活动——外科培训从数量到质量的范式转变。
Pub Date : 2025-12-01 Epub Date: 2025-09-04 DOI: 10.1007/s00104-025-02370-4
Mohammed Ibrahim, Steffen Axt, Judith Dechantsreiter, Adrian P Marty, Alfio Milazzo, André L Mihaljevic, Philipp Kron

Background: Since the 2020 revision of the medical training regulations surgical training in Germany has been based on the acquisition of knowledge (cognitive and methodological competence) as well as experience and skills (practical competence). As in previous training catalogues, minimum numbers are defined for essential operations; however, these operation catalogues do not reflect the actual surgical competence of residents.

Objective: This paper highlights the current challenges faced by prospective surgeons. It presents a perspective on a core competency-oriented surgical training model using entrustable professional activities (EPAs) and provides suggestions for the implementation and digitalization of surgical education based on EPAs.

Material and methods: Overview in the sense of a narrative review.

Results: The EPAs are clearly defined clinical tasks in the medical practice that can be entrusted to residents, observed and evaluated. The purpose of EPAs is the structured and continuous assessment of individual competencies in medical training. They are specific, embedded in the surgical routine and can support supervisors in implementing competency-based training. The EPAs serve to assess and promote surgical skills. Through digitalization tools such as smartphone applications, these evaluations can be integrated into daily clinical practice.

Discussion: In the future, surgical education should evolve towards competency-based learning. The use of EPAs enables a more practice-oriented training approach: moving away from the quantitative focus of procedure catalogues toward a qualitative improvement of surgical training.

背景:自2020年修订医疗培训条例以来,德国的外科培训一直以获取知识(认知和方法能力)以及经验和技能(实践能力)为基础。同以前的培训目录一样,为基本业务规定了最低人数;然而,这些手术目录并不能反映住院医师的实际手术能力。目的:探讨未来外科医生面临的挑战。提出了基于可委托专业活动(EPAs)的以核心能力为导向的外科培训模式,并对基于EPAs的外科教育实施和数字化提出了建议。材料和方法:以叙事性回顾的方式进行概述。结果:EPAs是医疗实践中明确界定的临床任务,可以委托给住院医师进行观察和评估。环境评估的目的是对医疗培训中的个人能力进行结构化和持续的评估。它们是具体的,嵌入在手术程序中,可以支持主管实施基于能力的培训。EPAs的作用是评估和提高手术技能。通过智能手机应用等数字化工具,这些评估可以整合到日常临床实践中。讨论:未来外科教育应向能力学习方向发展。EPAs的使用使培训方法更加以实践为导向:从程序目录的定量重点转向外科培训的定性改进。
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引用次数: 0
[Paravertebral block versus epidural catheter for perioperative analgesia in minimally invasive esophageal resection, results of the PEPMEN trial]. [椎旁阻滞与硬膜外导管在微创食管切除术围手术期镇痛的对比,PEPMEN试验的结果]。
Pub Date : 2025-12-01 Epub Date: 2025-10-02 DOI: 10.1007/s00104-025-02394-w
L Schiffmann, C J Bruns
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引用次数: 0
Presentation of a new preemptive endoscopic treatment concept in duodenal interventions exemplified by an iatrogenic duodenal perforation after percutaneous transrenal nephrostomy. English version. 以经皮肾肾造口术后医源性十二指肠穿孔为例,介绍一种新的内镜治疗方法在十二指肠干预中的应用。英文版本。
Pub Date : 2025-12-01 Epub Date: 2025-05-20 DOI: 10.1007/s00104-025-02300-4
V Betz, A Goerdt, R Kiesow, J Müller, B Riefel, E Scharsack, U Zimmermann, M Reeh, G Loske
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引用次数: 0
[Non-Unions of the lower extremities]. [下肢不连]。
Pub Date : 2025-12-01 Epub Date: 2025-10-22 DOI: 10.1007/s00104-025-02365-1
Dannik Haas, Carolina Vogel, Tanja C Maisenbacher, Marie K Reumann, Tina Histing, Benedikt J Braun

Non-Union is still a frequent and severe complication in fracture treatment and represents a major challenge for orthopedic trauma surgery. Due to chronic pain and loss of mobility, pseudarthrosis can lead to a considerable impairment of the individual quality of life and the often long duration of treatment represents a high socioeconomic burden. The lower extremities are most frequently affected due to the high biomechanical stress. A multimodal concept combining diagnostics and treatment is necessary to adequately address this complex clinical condition.

骨不连仍然是骨折治疗中常见和严重的并发症,是骨科创伤手术的主要挑战。由于慢性疼痛和活动能力丧失,假关节可导致个人生活质量的相当大的损害,并且通常需要较长的治疗时间,这是一个很高的社会经济负担。由于高生物力学应力,下肢最常受到影响。多模式的概念结合诊断和治疗是必要的,以充分解决这一复杂的临床状况。
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引用次数: 0
[The role of adrenal-preserving surgery in the treatment of aldosterone-producing adenomas]. [肾上腺保留手术在醛固酮产生性腺瘤治疗中的作用]。
Pub Date : 2025-12-01 Epub Date: 2025-10-17 DOI: 10.1007/s00104-025-02395-9
Natia Kvirkvelia, Detlef K Bartsch
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引用次数: 0
[Plastic reconstructive interventions after metabolic bariatric surgery]. [代谢减肥手术后的整形重建干预]。
Pub Date : 2025-12-01 Epub Date: 2025-11-18 DOI: 10.1007/s00104-025-02407-8
Marcus Kiehlmann, Benjamin Ziegler, Christoph Hirche

Reconstructive and plastic surgery plays an important role in the treatment of patients after bariatric surgery. The reconstruction of body form and function with body contouring procedures leads to a significant increase in the quality of life after achieving weight stability and stabilization of potential side effects of the bariatric treatment. From a surgical perspective tightening of the extremities and trunk play an important role. Precise knowledge of the anatomical structures and perfusion patterns of the generated skin flaps as well as a careful patient selection for reduction of perioperative complications are very important. In addition to the surgical procedures the accompanying measures with respect to dietary changes and exercise therapy are important keystones in the complex treatment of bariatric and postbariatric treatment patients.

重建和整形手术在减肥手术后患者的治疗中起着重要作用。在实现体重稳定和减肥治疗的潜在副作用稳定后,通过身体轮廓手术重建身体形态和功能可显著提高生活质量。从外科角度来看,四肢和躯干的收紧起着重要的作用。准确了解所生成皮瓣的解剖结构和灌注模式,以及仔细选择患者以减少围手术期并发症是非常重要的。除了外科手术外,饮食改变和运动治疗的相关措施是减肥和减肥后治疗患者复杂治疗的重要基石。
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引用次数: 0
[Comparison of the short-term and long-term results after pancreatic resection]. 【胰腺切除术后近期与远期疗效比较】。
Pub Date : 2025-12-01 Epub Date: 2025-10-10 DOI: 10.1007/s00104-025-02396-8
Laura Schwenk, Michael Ardelt, Utz Settmacher
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引用次数: 0
[Surgical interventions after metabolic bariatric surgery]. [代谢减肥手术后的手术干预]。
Pub Date : 2025-12-01 Epub Date: 2025-11-25 DOI: 10.1007/s00104-025-02406-9
F Seyfried, J Lauerer, C-T Germer
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引用次数: 0
[Orthopedic interventions after metabolic and bariatric surgery]. [代谢和减肥手术后的骨科干预]。
Pub Date : 2025-12-01 Epub Date: 2025-10-15 DOI: 10.1007/s00104-025-02390-0
Felix Haussner, Thomas Caffard, Tobias Freitag, Heiko Reichel, Robert Zahn

Overweight and obesity are among the leading causes of degenerative musculoskeletal disorders. As a consequence, the proportion of obese patients undergoing knee or hip joint arthroplasty or spinal surgery has significantly increased. In these interventions obese patients are at a higher risk for perioperative complications, including thromboembolic events, wound healing disorders, periprosthetic infections, implant failure and the need for revision surgery. A body mass index (BMI) >40 kg/m2 is considered a contraindication for many elective orthopedic procedures. Bariatric surgery can lead to rapid and sustained weight loss; however, the metabolic changes induced by these procedures can affect the absorption and bioavailability of nutrients and medications. At the same time, the altered metabolic state following bariatric surgery is associated with an increased risk of perioperative complications during orthopedic interventions. Furthermore, the efficacy of medications, such as analgesics, antimicrobial agents and oral anticoagulants can be significantly altered by metabolic and bariatric procedures. This article provides an overview of the specific considerations for orthopedic procedures following metabolic and bariatric surgery.

超重和肥胖是退行性肌肉骨骼疾病的主要原因。因此,肥胖患者接受膝关节或髋关节置换术或脊柱手术的比例明显增加。在这些干预措施中,肥胖患者围手术期并发症的风险更高,包括血栓栓塞事件、伤口愈合障碍、假体周围感染、植入物失败和需要翻修手术。体重指数(BMI) bbb40 kg/m2被认为是许多选择性骨科手术的禁忌症。减肥手术可以导致快速和持续的体重下降;然而,这些过程引起的代谢变化会影响营养物质和药物的吸收和生物利用度。同时,减肥手术后代谢状态的改变与骨科干预期间围手术期并发症的风险增加有关。此外,镇痛药、抗菌剂和口服抗凝血剂等药物的疗效可因代谢和减肥手术而显著改变。本文概述了代谢和减肥手术后整形手术的具体注意事项。
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Chirurgie (Heidelberg, Germany)
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