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Advances in biochemical psychopharmacology最新文献

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Amino acid neurotransmitters. 氨基酸神经递质。
Advances in biochemical psychopharmacology
Pub Date : 2001-04-19 DOI: 10.1038/NPG.ELS.0000010
J. Henley
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引用次数: 0
Toward a temperament-based approach to depression: implications for neurobiologic research. 走向以气质为基础的抑郁症治疗方法:对神经生物学研究的启示。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
H S Akiskal
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引用次数: 0
Neuroactive steroid modulation of GABAA receptors. GABAA受体的神经活性类固醇调节。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
R W Olsen, D W Sapp

In summary, the discovery of neuroactive steroids has led to a new appreciation of endocrine-nervous system interactions. The modulation of GABAA receptors by steroid hormone metabolites has far-reaching physiological and pharmacological implications, including relevance to human psychiatric and neurological problems (Fig. 7): I. MECHANISM OF GENERAL ANESTHESIA (Alphaxalone) II. GABA TONE IN SOME REGIONS (e.g., caudate) III. ANTI-ANXIETY ACTIVITY: (Post-partum depression, premenstrual syndrome?) (New drugs?) IV. CHILDBIRTH V. ANTIEPILEPTIC ACTIVITY (New drugs?) VI. REGIONAL HETEROGENEITY (Receptor subtypes) VII. PARTIAL AGONISTS (Better clinical profile?) FIG. 7. Implications of GABAA receptor as a nongenomic CNS target of steroids.

总之，神经活性类固醇的发现导致了对内分泌-神经系统相互作用的新认识。类固醇激素代谢物对GABAA受体的调节具有深远的生理和药理学意义，包括与人类精神和神经问题相关(图7):1 .全麻(Alphaxalone)机制2。某些区域(如尾状核)的GABA音调抗焦虑活动:(产后抑郁、经前综合症?)(新药?)四、分娩五、抗癫痫活性(新药?)区域异质性(受体亚型)部分激动剂(更好的临床表现?)图7所示。GABAA受体作为类固醇非基因组中枢神经系统靶点的意义。
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引用次数: 0
Animal models of different anxiety states. 不同焦虑状态的动物模型。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
S E File
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引用次数: 0
The long term prophylaxis of affective disorders. 情感性疾病的长期预防。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
A Koukopoulos, D Reginaldi, G Minnai, G Serra, L Pani, F N Johnson
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引用次数: 0
Animal models of mania. 躁狂的动物模型。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
G L Gessa, L Pani, G Serra, W Fratta
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引用次数: 0
A search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability. 寻找一种新的抗惊厥和抗焦虑的苯二氮卓类药物，无副作用和耐受性。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
E Costa, J Auta, H Caruncho, A Guidotti, F Impagnatiello, C Pesold, D M Thompson
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引用次数: 0
Pharmacological treatment of depression and comorbid anxiety disorders. 抑郁症和共病焦虑症的药物治疗。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
G B Cassano, S Michelini
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引用次数: 0
Benzodiazepine receptor function in anxiety disorders. 苯二氮卓受体在焦虑症中的作用。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
A L Malizia, N J Coupland, D J Nutt
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引用次数: 0
Depression and mania. From neurobiology to treatment. Introduction. 抑郁和狂躁。从神经生物学到治疗。介绍。
Advances in biochemical psychopharmacology
Pub Date : 1995-01-01
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引用次数: 0
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