Current treatment options in infectious diseases最新文献

{"title":"The Present and Future State of Antimicrobial Stewardship and Rapid Diagnostic Testing: Can One Ideally Succeed Without the Other?","authors":"K. Zeitler, Navaneeth Narayanan","doi":"10.1007/s40506-019-00190-9","DOIUrl":"https://doi.org/10.1007/s40506-019-00190-9","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"177-187"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-00190-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48941030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Infection Control for Clostridioides (Formerly Clostridium) difficile Infection","authors":"Carlos E Figueroa Castro, L. Munoz-Price","doi":"10.1007/s40506-019-0179-y","DOIUrl":"https://doi.org/10.1007/s40506-019-0179-y","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"12-22"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0179-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43986564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Procalcitonin as a Diagnostic, Therapeutic, and Prognostic Tool: a Critical Review","authors":"Fabricio Rodrigues Torres de Carvalho, Roberto Rabello Filho, Lucas Bulgarelli, A. Serpa Neto, R. Deliberato","doi":"10.1007/s40506-019-0178-z","DOIUrl":"https://doi.org/10.1007/s40506-019-0178-z","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2019-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0178-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52813997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovations in Quality Improvement of Intravascular Catheter-Related Bloodstream Infections","authors":"Rajendra Karnatak, M. Rupp, Kelly A. Cawcutt","doi":"10.1007/s40506-019-0180-5","DOIUrl":"https://doi.org/10.1007/s40506-019-0180-5","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"23-41"},"PeriodicalIF":0.0,"publicationDate":"2019-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0180-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44976584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Tuberculosis in Brazil—Past, Present, and Future Challenges","authors":"D. Jarovsky","doi":"10.1007/s40506-019-0182-3","DOIUrl":"https://doi.org/10.1007/s40506-019-0182-3","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"58-72"},"PeriodicalIF":0.0,"publicationDate":"2019-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0182-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47767782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Antibiotic Resistance: on the Cusp of a Post-antibiotic World","authors":"Kameron Sprigg, C. Pietrangeli","doi":"10.1007/s40506-019-0181-4","DOIUrl":"https://doi.org/10.1007/s40506-019-0181-4","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"42-57"},"PeriodicalIF":0.0,"publicationDate":"2019-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0181-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44996363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physician barriers to implementation of hospital-based antimicrobial stewardship programs (ASPs): a global perspective","authors":"L. Kaljee, Tyler Prentiss, M. Zervos","doi":"10.1007/s40506-019-0183-2","DOIUrl":"https://doi.org/10.1007/s40506-019-0183-2","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 1","pages":"73-80"},"PeriodicalIF":0.0,"publicationDate":"2019-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-019-0183-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43850269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on Adverse Effects of HIV Integrase Inhibitors.","authors":"Agnieszka Kolakowska, Anaenza Freire Maresca, Intira Jeannie Collins, Johann Cailhol","doi":"10.1007/s40506-019-00203-7","DOIUrl":"10.1007/s40506-019-00203-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>The goal of this paper is to provide an up-to-date review of adverse events related to the class of integrase strand transfer inhibitors (INSTIs), which became the class of choice in few years. We sought answers specifically to issues pertaining to neuropsychiatric adverse events, as well as weight gain, which were the two most important categories of adverse events raised in recent studies based on real-life experience. The primary focus of this paper is on adults with a brief summary on pregnant women and children/adolescents.</p><p><strong>Recent findings: </strong>Dolutegravir (DTG) bears the heaviest burden of neuropsychiatric side effects. Weight gain was reported with all INSTIs, although there are methodological caveats in the analyses and the findings need to be interpreted with caution.Moreover, due to recent findings on neural tube defects in infants exposed to dolutegravir during their peri-conception period, its use is not recommended for women of childbearing age without proper birth control method, while raltegravir remains the only drug which may be prescribed without caution. Given the importance of cognitive and metabolic co-morbidities in people living with HIV in regard to their quality of life, future research needs to focus on long-term effects of INSTIs in relation to these adverse events. Pharmacogenetics seems to be a promising tool. Safety during pregnancy is also another important issue to further clarify.</p><p><strong>Summary: </strong>INSTIs are a generally well-tolerated class of antiretrovirals (ARV), and has a higher antiviral potency compared to other classes of ARV.Clinicians and patients need however to be aware of some red flags when starting with and monitoring patients on INSTIs.All INSTIs can lead to mild increases in creatinine levels, usually without clinical significance, but caution is needed in patients with low eGFR (<30ml/min), when using other nephrotoxic drugs, such as as tenofovir disoproxil.Neuro-psychiatric (NP) effects are to be monitored with INSTIs, especially with DTG (though reports are at times contradictory); clinicians might want to avoid DTG for patients with history of severe NP symptoms, until clarity is provided.Weight gain was reported with all INSTIs, especially with DTG, with possible differential effects according to sex and ethnicity (female and non-white patients being at increased risk). This is worrying since patients from African descent are at higher risk of cardio-vascular events and increased body mass index (BMI) can cause further increase metabolic risk. There is possibly an additional effect of tenofovir alafenamide (TAF) on weight increase.Discrepancies between clinical trials - with low rates of adverse events - and reports from real-life settings might be due partly to under-representation of some groups of patients in clinical trials, and/or the short duration of follow-up, since some adverse effects may only occur after prolo","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"11 4","pages":"372-387"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38767623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Challenges in Antibiotic Stewardship in Low- and Middle-Income Countries","authors":"A. Galindo-Fraga, M. Villanueva-Reza, E. Ochoa-Hein","doi":"10.1007/s40506-018-0175-7","DOIUrl":"https://doi.org/10.1007/s40506-018-0175-7","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"10 1","pages":"421-429"},"PeriodicalIF":0.0,"publicationDate":"2018-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-018-0175-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48920299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Botryomycosis and Staphylococcus aureus: Diagnosis, Management, and a Systemic Literature Review","authors":"Pamela Bailey, Jillian E. Raybould, Sangeeta Sastry, G. Bearman","doi":"10.1007/s40506-018-0176-6","DOIUrl":"https://doi.org/10.1007/s40506-018-0176-6","url":null,"abstract":"","PeriodicalId":72759,"journal":{"name":"Current treatment options in infectious diseases","volume":"10 1","pages":"347-361"},"PeriodicalIF":0.0,"publicationDate":"2018-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40506-018-0176-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44202741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}