Pub Date : 2026-01-12DOI: 10.1007/s00101-025-01632-4
Michael Niedermair, Maria Rabl, Christiane Lentes, Bernhard Zelle, Eva Neuhierl, Bernhard Furtner, Lennar Riesinger, Uwe Wintergerst, Florian Neuhierl
{"title":"[Postdural puncture headache in a 9-year-old female patient: treatment options and trajectory].","authors":"Michael Niedermair, Maria Rabl, Christiane Lentes, Bernhard Zelle, Eva Neuhierl, Bernhard Furtner, Lennar Riesinger, Uwe Wintergerst, Florian Neuhierl","doi":"10.1007/s00101-025-01632-4","DOIUrl":"https://doi.org/10.1007/s00101-025-01632-4","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1007/s00101-025-01638-y
Martin Schuster
{"title":"Desflurane, sustainability and the diversity of the anesthesiological armamentarium.","authors":"Martin Schuster","doi":"10.1007/s00101-025-01638-y","DOIUrl":"https://doi.org/10.1007/s00101-025-01638-y","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00101-025-01634-2
Thorsten Walter, Mareike Schimmel, Stefan Siegert, Lars Behrens
{"title":"[A 4-year-old girl with traumatic carotid artery dissection and subsequent infarction of the middle cerebral artery].","authors":"Thorsten Walter, Mareike Schimmel, Stefan Siegert, Lars Behrens","doi":"10.1007/s00101-025-01634-2","DOIUrl":"https://doi.org/10.1007/s00101-025-01634-2","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00101-025-01633-3
M Vijayasimha
{"title":"Operationalizing the 2025 S3 sepsis update in the ICU: three immediate auditable practice levers for safer, faster care.","authors":"M Vijayasimha","doi":"10.1007/s00101-025-01633-3","DOIUrl":"https://doi.org/10.1007/s00101-025-01633-3","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00101-025-01628-0
Josefin Grabert, Ehrenfried Schindler
Even experienced anesthesiologists can be challenged when establishing a central venous catheter in children. In addition to the classical indications, a difficult peripheral vein access represents a relevant indication for a central venous catheter to avoid repeated traumatic puncture attempts. The size of the catheter utilized depends on the body weight and the vein diameter to prevent thrombotic complications. Irrespective of the chosen vein, the puncture should be performed under direct sonographic visualization of the needle tip and subsequently the wire. The internal jugular vein is the vessel of choice for the site of puncture due to its accessibility for sonography, ease of catheter placement and management as well as valuable hemodynamic information. To avoid exposure to ionizing radiation, the catheter tip positioning should be verified using sonography (transthoracic echocardiography, TTE) or intracavitary electrocardiography (ECG). The indications and dwell time should be critically assessed for all catheter placements to avoid complications such as catheter-associated bloodstream infections and thrombosis.
{"title":"[Placement of central venous catheters in pediatric anesthesia : Indications, techniques and complications].","authors":"Josefin Grabert, Ehrenfried Schindler","doi":"10.1007/s00101-025-01628-0","DOIUrl":"https://doi.org/10.1007/s00101-025-01628-0","url":null,"abstract":"<p><p>Even experienced anesthesiologists can be challenged when establishing a central venous catheter in children. In addition to the classical indications, a difficult peripheral vein access represents a relevant indication for a central venous catheter to avoid repeated traumatic puncture attempts. The size of the catheter utilized depends on the body weight and the vein diameter to prevent thrombotic complications. Irrespective of the chosen vein, the puncture should be performed under direct sonographic visualization of the needle tip and subsequently the wire. The internal jugular vein is the vessel of choice for the site of puncture due to its accessibility for sonography, ease of catheter placement and management as well as valuable hemodynamic information. To avoid exposure to ionizing radiation, the catheter tip positioning should be verified using sonography (transthoracic echocardiography, TTE) or intracavitary electrocardiography (ECG). The indications and dwell time should be critically assessed for all catheter placements to avoid complications such as catheter-associated bloodstream infections and thrombosis.</p>","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1007/s00101-025-01639-x
Peter Kranke, Robert Kleinberg, Patrick Meybohm, Beverly K Philip, Laurentiu Marin, Kai Zacharowski
{"title":"Anesthetic diversity: a pillar of healthcare system resilience and a strategic imperative in an era of uncertainty.","authors":"Peter Kranke, Robert Kleinberg, Patrick Meybohm, Beverly K Philip, Laurentiu Marin, Kai Zacharowski","doi":"10.1007/s00101-025-01639-x","DOIUrl":"https://doi.org/10.1007/s00101-025-01639-x","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1007/s00101-025-01625-3
Peter Schnuelle, Benito Yard
{"title":"Antioxidative Spenderkonditionierung mit Dopamin zur Verbesserung der Transplantatfunktion nach Nierentransplantation.","authors":"Peter Schnuelle, Benito Yard","doi":"10.1007/s00101-025-01625-3","DOIUrl":"https://doi.org/10.1007/s00101-025-01625-3","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1007/s00101-025-01637-z
Martin Schuster
{"title":"[Desflurane, sustainability and the diversity of the anaesthesiological armamentarium].","authors":"Martin Schuster","doi":"10.1007/s00101-025-01637-z","DOIUrl":"https://doi.org/10.1007/s00101-025-01637-z","url":null,"abstract":"","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-18DOI: 10.1007/s00101-025-01618-2
Y Kropp, K Barthel, G Beck, M Thiel, C Tsagogiorgas, M Otto
<p><strong>Background: </strong>Aerosol therapy is widely used in tracheostomized patients, particularly during prolonged weaning, to improve mucociliary clearance and manage bronchoconstriction; however, there is a lack of standardized guidelines to optimize nebulization therapy in this patient population. Different nebulizer types and interfaces can affect the efficiency of drug deposition, thereby affecting the therapeutic efficacy. Understanding these differences is essential to improve aerosol delivery strategies in clinical practice.</p><p><strong>Objective: </strong>This in vitro study aimed to evaluate the drug deposition rates of different aerosol generators and interfaces to determine the most effective combination for spontaneously breathing tracheostomized patients. Specifically, we compared the performance of a jet nebulizer and a vibrating mesh nebulizer in combination with different delivery interfaces: a face mask, a tracheostomy mask and a T-piece connected directly to the tracheostomy tube.</p><p><strong>Material and methods: </strong>The study used an in vitro model simulating a spontaneously breathing tracheostomized patient. Drug deposition rates were measured using a jet nebulizer (Cirrus™ 2, Intersurgical Beatmungsgeräte GmbH, Sankt Augustin, Germany) and a vibrating mesh nebulizer (Aerogen® Solo, Aerogen Ltd., Galway, Ireland). The aerosol was delivered with the help of a face mask, a tracheal mask and a T-piece. The lung deposition rate was quantified gravimetrically by analyzing salbutamol deposition in a filter placed at the simulated airway.</p><p><strong>Results: </strong>The vibrating mesh nebulizer demonstrated the highest drug deposition rate (19.32 ± 4.29%) when used with a T-piece, significantly outperforming the jet nebulizer, which achieved its highest deposition rate (12.33 ± 1.38%) with a face mask (p = 0.008). The mesh nebulizer also achieved a higher deposition rate than the jet nebulizer when a tracheostomy mask was used (p = 0.023 with 1 l O<sub>2</sub>/min supplementary flow, p < 0.001 with 8 l O<sub>2</sub>/min).</p><p><strong>Conclusion: </strong>The results suggest that the use of a vibrating mesh nebulizer connected directly to the tracheostomy tube via a T-piece can improve aerosol delivery efficiency in spontaneously breathing tracheostomized patients. The T‑piece functions as a small reservoir when a vibrating mesh nebulizer is used without additional oxygen supply, improving the deposition efficiency. Conversely, jet nebulizers require a continuous oxygen/air flow for operation; this can result in significant drug loss when used with a T-piece due to the continuous release of aerosol through the distal T‑piece opening. These findings are consistent with previous studies highlighting the benefits of mesh nebulizers in mechanically ventilated patients but extend this knowledge to spontaneously breathing tracheostomized individuals. Further clinical research is required to validate these in vitro re
{"title":"[Aerosol therapy in spontaneously breathing tracheostomized patients: an in vitro study].","authors":"Y Kropp, K Barthel, G Beck, M Thiel, C Tsagogiorgas, M Otto","doi":"10.1007/s00101-025-01618-2","DOIUrl":"10.1007/s00101-025-01618-2","url":null,"abstract":"<p><strong>Background: </strong>Aerosol therapy is widely used in tracheostomized patients, particularly during prolonged weaning, to improve mucociliary clearance and manage bronchoconstriction; however, there is a lack of standardized guidelines to optimize nebulization therapy in this patient population. Different nebulizer types and interfaces can affect the efficiency of drug deposition, thereby affecting the therapeutic efficacy. Understanding these differences is essential to improve aerosol delivery strategies in clinical practice.</p><p><strong>Objective: </strong>This in vitro study aimed to evaluate the drug deposition rates of different aerosol generators and interfaces to determine the most effective combination for spontaneously breathing tracheostomized patients. Specifically, we compared the performance of a jet nebulizer and a vibrating mesh nebulizer in combination with different delivery interfaces: a face mask, a tracheostomy mask and a T-piece connected directly to the tracheostomy tube.</p><p><strong>Material and methods: </strong>The study used an in vitro model simulating a spontaneously breathing tracheostomized patient. Drug deposition rates were measured using a jet nebulizer (Cirrus™ 2, Intersurgical Beatmungsgeräte GmbH, Sankt Augustin, Germany) and a vibrating mesh nebulizer (Aerogen® Solo, Aerogen Ltd., Galway, Ireland). The aerosol was delivered with the help of a face mask, a tracheal mask and a T-piece. The lung deposition rate was quantified gravimetrically by analyzing salbutamol deposition in a filter placed at the simulated airway.</p><p><strong>Results: </strong>The vibrating mesh nebulizer demonstrated the highest drug deposition rate (19.32 ± 4.29%) when used with a T-piece, significantly outperforming the jet nebulizer, which achieved its highest deposition rate (12.33 ± 1.38%) with a face mask (p = 0.008). The mesh nebulizer also achieved a higher deposition rate than the jet nebulizer when a tracheostomy mask was used (p = 0.023 with 1 l O<sub>2</sub>/min supplementary flow, p < 0.001 with 8 l O<sub>2</sub>/min).</p><p><strong>Conclusion: </strong>The results suggest that the use of a vibrating mesh nebulizer connected directly to the tracheostomy tube via a T-piece can improve aerosol delivery efficiency in spontaneously breathing tracheostomized patients. The T‑piece functions as a small reservoir when a vibrating mesh nebulizer is used without additional oxygen supply, improving the deposition efficiency. Conversely, jet nebulizers require a continuous oxygen/air flow for operation; this can result in significant drug loss when used with a T-piece due to the continuous release of aerosol through the distal T‑piece opening. These findings are consistent with previous studies highlighting the benefits of mesh nebulizers in mechanically ventilated patients but extend this knowledge to spontaneously breathing tracheostomized individuals. Further clinical research is required to validate these in vitro re","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":"12-19"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12804279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and aim: Awake craniotomy and deep brain stimulation (DBS) procedures require the patient to be awake and adequate anesthesia conditions are typically achieved using a scalp block. These procedures inherently involve some degree of pain from local anesthetic injections during scalp block administration. We aimed to reduce the injection pain in scalp blocks using a vibration stimulus.
Methods: A total of 56 patients aged between 18 and 75 years undergoing awake craniotomy and DBS procedures were enrolled in the study. All patients received a loading dose of dexmedetomidine before scalp block administration. Local anesthetic injections were applied sequentially to the identically named nerves on the right and left sides of the head. A vibration device was used during injections on one side, while injections on the other side were performed without vibration. The numeric rating scale (NRS) score and hemodynamic measurements during each injection, including heart rate and mean arterial pressure were compared between vibration and nonvibration sides.
Results: The NRS scores were lower on the side where vibration was used during scalp block injections (P < 0.001). Additionally, there was a decrease in heart rate and mean arterial pressure on the side where vibration was used compared to the baseline value (P < 0.005).
Conclusion: The study showed that using topical vibration during a scalp block can decrease the pain of a local anesthetic injection and maintain hemodynamic stability.
{"title":"Effect of topical vibration on pain during scalp block injections in awake craniotomy and deep brain stimulation surgery : Analgesic effects of vibratory stimulation during scalp blocks.","authors":"Nur Yilmaz, Ceyda Ozhan Caparlar, Aylin Kilincarslan, Fatma Ozkan Sipahioglu, Derya Ozkan, Caner Unluer","doi":"10.1007/s00101-025-01604-8","DOIUrl":"10.1007/s00101-025-01604-8","url":null,"abstract":"<p><strong>Background and aim: </strong>Awake craniotomy and deep brain stimulation (DBS) procedures require the patient to be awake and adequate anesthesia conditions are typically achieved using a scalp block. These procedures inherently involve some degree of pain from local anesthetic injections during scalp block administration. We aimed to reduce the injection pain in scalp blocks using a vibration stimulus.</p><p><strong>Methods: </strong>A total of 56 patients aged between 18 and 75 years undergoing awake craniotomy and DBS procedures were enrolled in the study. All patients received a loading dose of dexmedetomidine before scalp block administration. Local anesthetic injections were applied sequentially to the identically named nerves on the right and left sides of the head. A vibration device was used during injections on one side, while injections on the other side were performed without vibration. The numeric rating scale (NRS) score and hemodynamic measurements during each injection, including heart rate and mean arterial pressure were compared between vibration and nonvibration sides.</p><p><strong>Results: </strong>The NRS scores were lower on the side where vibration was used during scalp block injections (P < 0.001). Additionally, there was a decrease in heart rate and mean arterial pressure on the side where vibration was used compared to the baseline value (P < 0.005).</p><p><strong>Conclusion: </strong>The study showed that using topical vibration during a scalp block can decrease the pain of a local anesthetic injection and maintain hemodynamic stability.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov (NCT06038825).</p>","PeriodicalId":72805,"journal":{"name":"Die Anaesthesiologie","volume":" ","pages":"20-27"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}