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[The updated S3 guidelines: sedation in gastrointestinal endoscopy : Innovations and relevant aspects for the routine].
Pub Date : 2025-02-01 Epub Date: 2025-02-13 DOI: 10.1007/s00101-025-01501-0
Peter H Tonner, Till Wehrmann, Andrea Riphaus

In 2023 the third revision of the S3 guidelines on sedation in gastrointestinal endoscopy was presented. As with the two previous versions of the guidelines, the relevant and current literature was reviewed and evaluated by a group of experts from various specialist societies under the guidance of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS). In addition to confirming some of the older recommendations, a number of recommendations were revised or newly added. A brief overview of the current version of the S3 guidelines is provided with a focus on relevant changes.

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引用次数: 0
[What holds the hospital together-A "fixation error" in terms of patient safety].
Pub Date : 2025-02-01 Epub Date: 2025-01-30 DOI: 10.1007/s00101-025-01504-x
Richard Schalk, Benedict Peters, Hermann Heinze, Jörn Puls, Valery Kitz

Background: Fixation plasters are nowadays an important part of clinical care and the product range is adapted to the needs of patient care. A multifaceted selection is available.

Aim of the study: To increase vigilance towards the supposedly low-threshold use of fixation plasters in patient care.

Material and method: This review is dedicated to the use of fixation plasters, mostly outside of their intended use on patients.

Results: There are countless examples of how fixation plasters are used outside of their intended purpose and patient safety is often neglected. This can lead to an occult latex contamination. Devices repaired with makeshift fixation plasters also put patients at risk. From a hygienic point of view, adhesive residues from fixation plasters promote surface contamination of various materials or work surfaces.

Discussion: The intended use of medical products is meaningful and prescribed by law. This serves to ensure patient and user safety. Further training is extremely important so that vigilant players in the healthcare sector can counteract sources of danger. This special attention can be trained in the "room of error", for example, and is one of the most important preventative measures to avoid errors occurring in the first place. Checking the use of fixation plasters in one's own working environment helps to minimize risks.

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引用次数: 0
Impending esophago-arterial fistula after battery ingestion-First preventive operation on a toddler worldwide. 电池摄入后即将发生的食管动脉瘘-全球首例幼儿预防性手术。
Pub Date : 2025-01-08 DOI: 10.1007/s00101-024-01487-1
Judith Lohmann, Tobias Klein, Martin Stenzel, Marko Aleksic, Paul Fuchs, Thomas Boemers, Jost Kaufmann
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引用次数: 0
[The time after - Late sequelae of intensive care treatment: successes and challenges]. [后时间-重症监护治疗的晚期后遗症:成功与挑战]。
Pub Date : 2025-01-01 Epub Date: 2025-01-17 DOI: 10.1007/s00101-024-01494-2
Konrad Schmidt
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引用次数: 0
Erratum zu: Intraoperative Hypotonie beim Kind – Messung und Therapie. 儿童术内低血压:测量与治疗。
Pub Date : 2025-01-01 DOI: 10.1007/s00101-024-01495-1
Sebastian Bratke, Sebastian Schmid, Vijyant Sabharwal, Bettina Jungwirth, Karin Becke-Jakob
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引用次数: 0
[Intensive care treatment of cardiac surgery patients: focus on hemodynamics]. 【心脏手术患者的重症监护治疗:以血流动力学为重点】。
Pub Date : 2025-01-01 DOI: 10.1007/s00101-024-01497-z
Heidi Görler

Hemodynamic treatment is a core task in the intensive medical care of cardiac surgery patients. The patient's underlying disease, the type of surgical procedure and the patient's individual characteristics play key roles in the selection of the treatment regimen. The basis of any targeted hemodynamic treatment is the differential diagnosis of the underlying pathological disorder. The established basic monitoring can be expanded if necessary. Postoperative circulatory dysfunction can occur as low cardiac output syndrome (LCOS) predominantly with left or right heart failure or as vasoplegic syndrome (VS). In addition to catecholamines in the narrow sense, various vasoactive and inotropic substances are available for treatment. Knowledge of the recommended target parameters and indication-appropriate monitoring are essential. This article summarizes the current guideline recommendations for the treatment of postoperative circulatory dysfunction.

血流动力学治疗是心脏外科病人重症监护的一项核心任务。患者的基础疾病、手术类型和患者的个体特征在治疗方案的选择中起着关键作用。任何靶向血流动力学治疗的基础是对潜在病理障碍的鉴别诊断。如有必要,可扩展已建立的基本监测。术后循环功能障碍可表现为低心输出量综合征(LCOS),主要伴有左或右心力衰竭或血管麻痹综合征(VS)。除了狭义的儿茶酚胺外,还有各种血管活性物质和肌力物质可用于治疗。了解推荐的目标参数和适合适应症的监测是必不可少的。本文总结了目前治疗术后循环功能障碍的指南建议。
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引用次数: 0
[Alfred Kirstein-A pioneer of direct laryngoscopy]. [Alfred kirstein -直接喉镜检查的先驱]。
Pub Date : 2025-01-01 Epub Date: 2024-12-12 DOI: 10.1007/s00101-024-01492-4
M Goerig

On 23 April 1895, the Berlin ENT medical specialist Alfred Kirstein performed the first direct examination of the larynx using a Casper esophagoscope equipped with electric lighting, which he called an "autoscope". The examination of the larynx, which had previously only been possible indirectly using mirror systems, was named by him "autoscopy". The development of the device enabled a more precise observation than before and laryngeal or tracheal foreign bodies could be removed better and more easily. The new instrumental development and examination technique he described met with rapid approval and great interest in specialist circles. Shortly afterwards the first publications on orotracheal intubation for anesthesia appeared in scientific journals, that should also be possible with the aid of Kirstein's autoscope. Although he never propagated this himself, it was also possible to perform these under visualization using a tongue depressor equipped with a light, which he had developed a short time later. Both developments are already very close to today's laryngoscopes. Kirstein's contribution in this respect has so far hardly been appreciated, especially in German-speaking countries.

1895 年 4 月 23 日,柏林耳鼻喉科医学专家阿尔弗雷德-基尔斯泰因(Alfred Kirstein)首次使用装有电灯的卡斯帕食道镜对喉部进行了直接检查,他称之为 "自动喉镜"。他将这种以前只能通过镜像系统间接检查喉部的方法命名为 "自动喉镜"。该设备的开发使观察比以前更加精确,喉部或气管异物也可以更好、更容易地取出。他所描述的新仪器开发和检查技术很快得到了专家们的认可和极大兴趣。此后不久,科学杂志上就出现了第一批关于气管插管麻醉的文章,而借助克尔斯廷的自动喉镜也可以实现这一点。虽然他本人从未推广过这一技术,但他在不久后研制出的带有照明装置的压舌板也可以在可视情况下进行插管。这两项技术的发展已经非常接近今天的喉镜。基尔斯泰因在这方面的贡献至今几乎没有得到重视,尤其是在德语国家。
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引用次数: 0
[Focus neurological intensive care medicine 2023/2024 : Summary of selected studies in intensive medical care]. [焦点神经重症医学2023/2024:重症监护研究综述]。
Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI: 10.1007/s00101-024-01490-6
Dominik Michalski, Christine Jungk, Christopher Beynon, Thorsten Brenner, Christian Nusshag, Christopher J Reuß, Mascha O Fiedler-Kalenka, Michael Bernhard, Andreas Hecker, Markus A Weigand, Maximilian Dietrich
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引用次数: 0
[Post-Intensive Care Syndrome: functional impairments of critical illness survivors]. [重症监护后综合症:危重病幸存者的功能障碍]。
Pub Date : 2025-01-01 Epub Date: 2024-12-16 DOI: 10.1007/s00101-024-01483-5
Nicolas Paul, Björn Weiss

With a decrease in mortality of critically ill patients in recent years, intensive care medicine research has shifted its focus on functional impairments of intensive care units (ICU) survivors. ICU survivorship is characterized by long-term impairments of cognition, mental health, and physical health. Since 2012, these impairments have been summarized with the umbrella term Post-Intensive Care Syndrome (PICS). Mental health impairments frequently entail new are aggravated symptoms of depression, anxiety, and posttraumatic stress disorder. Beyond impairments in the three PICS domains, critical illness survivors frequently suffer from chronic pain, dysphagia, and nutritional deficiencies. Furthermore, they have a higher risk for osteoporosis, bone fractures, and diabetes mellitus. Taken together, these sequelae reduce their health-related quality of life. Additionally, ICU survivors are challenged by social problems such as isolation, economic problems such as treatment costs and lost earnings, and return to previous employment. Yet, patients and caregivers have described post-ICU care as inadequate and fragmented. ICU follow-up clinics could improve post-ICU care, but there is insufficient evidence for their effectiveness. Thus far, large high-quality trials with multicomponent and interdisciplinary post-ICU interventions have mostly failed to improve patient outcomes. Hence, preventing PICS and minimizing risk factors by optimizing ICU care is crucial, e.g. by implementing the ABCDE bundle. Future studies need to identify effective components of post-ICU recovery interventions and determine which patient populations may benefit most from ICU recovery services.

近年来,随着重症患者死亡率的下降,重症监护医学研究的重点已转向重症监护病房(ICU)幸存者的功能障碍。ICU生存的特点是认知、心理健康和身体健康的长期损害。自2012年以来,这些损伤被概括为重症监护后综合征(PICS)。精神健康损害经常导致新的加重的抑郁、焦虑和创伤后应激障碍症状。除了三个PICS区域的损伤外,危重疾病幸存者经常遭受慢性疼痛、吞咽困难和营养缺乏。此外,他们患骨质疏松症、骨折和糖尿病的风险更高。总之,这些后遗症降低了他们与健康相关的生活质量。此外,重症监护病房幸存者还面临社会问题(如孤立)、经济问题(如治疗费用和收入损失)以及重返以前的工作岗位等挑战。然而,患者和护理人员描述后icu护理是不充分和分散的。ICU门诊随访可以改善ICU后护理,但其有效性证据不足。到目前为止,采用多成分和跨学科icu后干预措施的大型高质量试验大多未能改善患者的预后。因此,通过优化ICU护理来预防PICS和最小化风险因素至关重要,例如通过实施ABCDE bundle。未来的研究需要确定ICU后康复干预的有效组成部分,并确定哪些患者群体可能从ICU康复服务中获益最多。
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引用次数: 0
[Treatment quality with and without an electronic cognitive aid for emergencies in anaesthesia (eGENA) : The DANGER pilot study part 2 in randomized controlled in-situ emergency simulations]. [麻醉紧急情况下使用和不使用电子认知辅助设备的治疗质量(eGENA):随机对照现场紧急情况模拟中的DANGER试点研究第2部分]。
Pub Date : 2025-01-01 Epub Date: 2025-01-10 DOI: 10.1007/s00101-024-01493-3
Florian Rückert, Victoria Truxa, Philipp Dussmann, Thomas Schmidt, Timo Seyfried
<p><strong>Background: </strong>The electronic cognitive aid for emergencies in anesthesia (eGENA) is an app that offers digital support in anesthesiological emergency situations as a cognitive aid tool via checklists for memory and making decisions. The eGENA was published by the German Society of Anesthesiology and has been implemented in the emergency management of the anesthesiological team of the clinic in Potsdam, Germany.</p><p><strong>Objective: </strong>The primary endpoint was to observe the influence of eGENA on the anesthesiological emergency management on the subjective feeling of assurance as well as on quality of treatment and, therefore, patient safety.</p><p><strong>Material and methods: </strong>All employees in the anesthesia department (nursing staff and physicians) took part in the initial implementation of eGENA. The implementation phase covered crew resource management (CRM) principles and eGENA use as well as 10 case studies that were discussed with help from eGENA. Afterwards in a randomized controlled simulation study, realistic case studies were processed and evaluated. In this, 18 cases were handled by 9 groups with 4 persons in each group. Treatment during these simulations was assessed using a predetermined 20-point evaluation form and 10 resuscitation-related and 10 case-related points were awarded. Significance tests were carried out using the Wilcoxon-test (significance level p < 0.05) and two evaluations were completed by the attendees at the beginning and the end of the eGENA implementation process.</p><p><strong>Results: </strong>Scenarios 1 and 2 showed comparable overall scores (14.9 vs. 16.3 points out of 20, not significant). Higher case-associated scores (7.6 vs. 5.6 out of 10, p = 0.03) and higher total scores were achieved with the help of eGENA (16.9 vs. 14.3 out of 20, p = 0.02). Resuscitation-associated scores did not differ significantly (9.3 vs. 8.8 of 10, p = 0.1). During eGENA use for cases the execution of the algorithm-based resuscitation measures was not delayed or accelerated. With eGENA, however, differential diagnoses were discussed significantly more frequently and expanded treatment and diagnostic measures were implemented. During simulation cases eGENA was mainly used by physicians. The initially very positive responses of the evaluations toned down over time. Planned eGENA use for self-study was less frequent (p = 0.006) and there was less approval of the quality of treatment by eGENA than in the first survey (p = 0.002). The cooperation between doctors and nurses in emergency treatment showed an improvement (p < 0.001). The questions about self-assessed safety in emergency treatment on a scale from 0 to 10 showed higher values in all categories at the second survey (except only circulatory emergencies and 'other' emergencies). The respondents were more likely to be involved in emergency treatment at the second time of the survey (p = 0.03) after a median of 20 months.</p><p><strong>Disc
背景:eGENA (electronic cognitive aid for emergencies in anesthesia,简称eGENA)是一款在麻醉紧急情况下提供数字支持的应用程序,作为一种认知援助工具,通过清单来帮助患者记忆和决策。eGENA由德国麻醉学学会出版,并已在德国波茨坦诊所麻醉团队的急救管理中实施。目的:主要目的是观察eGENA对麻醉急救管理的影响,对主观安全感的影响,对治疗质量的影响,进而对患者安全的影响。材料和方法:麻醉科所有员工(护理人员和内科医生)都参与了eGENA的初步实施。实施阶段涵盖了机组资源管理(CRM)原则和eGENA的使用,以及在eGENA的帮助下讨论的10个案例研究。随后在随机对照模拟研究中,对现实案例研究进行了处理和评估。其中18宗个案由9组处理,每组4人。在这些模拟过程中,使用预定的20分评估表格对治疗进行评估,10分与复苏相关,10分与病例相关。使用wilcoxon检验进行显著性检验(显著性水平p )结果:方案1和方案2显示了可比较的总体得分(14.9分对16.3分,满分20分,无显著性)。在eGENA的帮助下,患者获得了更高的病例相关评分(7.6比5.6,p = 0.03)和更高的总分(16.9比14.3,p = 0.02)。复苏相关评分无显著差异(9.3比8.8,p = 0.1)。在病例使用eGENA期间,基于算法的复苏措施的执行没有延迟或加速。然而,对于eGENA,鉴别诊断的讨论明显更加频繁,并且实施了扩展的治疗和诊断措施。在模拟病例中,eGENA主要由医生使用。随着时间的推移,最初非常积极的评价反应逐渐减弱。计划eGENA用于自学的频率较低(p = 0.006),对eGENA治疗质量的认可程度低于第一次调查(p = 0.002)。医生和护士在急诊治疗中的合作有所改善(p )讨论:在观察期间,安全感和急诊参与显著增加。随着时间的推移,在日常生活中使用eGENA的最初需求已经减少;然而,这些结果与eGENA没有因果关系。使用eGENA不会改善复苏工作,但也不会延迟复苏工作。通过使用eGENA,可以取得更好的与病例相关的结果,并在复杂的紧急情况下更频繁地实施先进的诊断和治疗。这提高了治疗的质量。进一步的研究应以更多的案例进行,以证实所显示的效果。
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