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Anaphylactic shock with cardiac arrest triggered by tranexamic acid : A case report and review of the literature. 氨甲环酸诱发过敏性休克并心脏骤停:1例报告及文献复习。
Pub Date : 2025-01-01 Epub Date: 2024-12-10 DOI: 10.1007/s00101-024-01491-5
Andrina Neff, Anna Grünewald, Andrei Korbut, Johannes Erhardt, Daniel Yerly, Barbara Ballmer-Weber, Thomas Heidegger
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引用次数: 0
[Impending oesophago-arterial fistula after battery ingestion-the world's first preventive surgical intervention in a toddler]. [电池摄入后即将发生的食道动脉瘘-世界上第一次对幼儿进行预防性手术干预]。
Pub Date : 2025-01-01 Epub Date: 2025-01-08 DOI: 10.1007/s00101-024-01477-3
Judith Lohmann, Tobias Klein, Martin Stenzel, Marko Aleksic, Paul Fuchs, Thomas Boemers, Jost Kaufmann
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引用次数: 0
[Environmental sustainability in intensive care medicine]. [重症监护医学的环境可持续性]。
Pub Date : 2024-12-12 DOI: 10.1007/s00101-024-01485-3
Martin Schuster, Thomas Bein

Intensive care medicine is an area with a particularly high consumption of resources. This review presents important new findings relating to the environmental sustainability of intensive care medicine. For example, the drugs used in intensive care medicine can end up in the environment and cause relevant ecotoxicity. The consumption of material items is very high in intensive care medicine and the increasing replacement of reusable items by disposable items is a major problem. Simple measures can reduce the ecological footprint of materials and introduce the recycling of waste in intensive care units. The high energy consumption of air conditioning, lighting and medical technology varies between facilities but in most cases is substantial and can be significantly reduced through appropriate measures. Ideally, the consumption should be measured and analyzed in detail. In the future, support from artificial intelligence is conceivable in this aspect. Sustainability must be given a much higher priority in the training, continued and advanced education in intensive care medicine than it has been to date and in intensive care research sustainability aspects should be given equal consideration alongside economic aspects when it comes to assessing otherwise equivalent treatments. It is particularly important to avoid the misuse and overuse of intensive care. It brings no benefit to patients and hinders needs-based treatment that is oriented towards the patient's well-being. In addition, misuse and overuse increases costs and drives up the consumption of resources and thus the ecological footprint. Sustainability in the intensive care unit can only be achieved as a team. Various approaches are presented on how a networked Green Team can promote sustainability in the intensive care unit.

重症监护医学是一个资源消耗特别高的领域。本综述介绍了有关重症监护医学环境可持续性的重要新发现。例如,重症监护医学中使用的药物最终会进入环境并造成相关的生态毒性。重症监护医学对材料的消耗量非常大,而一次性物品越来越多地取代可重复使用物品也是一个主要问题。简单的措施就能减少材料的生态足迹,并在重症监护病房推行废物回收利用。空调、照明和医疗技术的高能耗因设施而异,但在大多数情况下都相当可观,可以通过适当的措施大幅降低。理想情况下,应详细测量和分析能耗。未来,人工智能在这方面的支持是可以想象的。在重症监护医学的培训、继续教育和进修中,必须比现在更加重视可持续性,在重症监护研究中,在评估其他同等治疗方法时,应将可持续性与经济性放在同等重要的位置。避免滥用和过度使用重症监护尤为重要。这不会给患者带来任何益处,反而会阻碍以患者福祉为导向的按需治疗。此外,滥用和过度使用还会增加成本,加剧资源消耗,进而增加生态足迹。重症监护室的可持续性只能通过团队来实现。本文介绍了网络化绿色团队如何促进重症监护病房可持续发展的各种方法。
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引用次数: 0
Exchange rates of second generation Microcuff® pediatric endotracheal tubes in children weighing more than 3 kg : A retrospective audit. 体重超过3 kg的儿童使用第二代Microcuff®小儿气管内管的比率:回顾性审计。
Pub Date : 2024-12-01 Epub Date: 2024-11-28 DOI: 10.1007/s00101-024-01486-2
Ilka Schmidt-Deubig, Michael Kemper, Pedro D Wendel-Garcia, Markus Weiss, Jörg Thomas, Christian Peter Both, Achim Schmitz

Background: Cuffed endotracheal tubes (cETT) pose the potential advantage of an infrequent need for reintubation in pediatric patients compared to uncuffed tubes. The aim of this study was to investigate tube exchange rates using second generation Microcuff® pediatric endotracheal tubes (PET) with an adapted sizing recommendation in a large single institution cohort of children and to identify potential variables associated with an elevated risk of tube exchange.

Methods: Patient data obtained from the electronic patient data management system of the Department of Anesthesia, University Children's Hospital Zurich, Switzerland, were retrospectively assessed for demographic and anthropometric information, size of the internal tube diameter used for positive pressure ventilation and divergence from the size recommendation chart.

Results: Data from 14,188 children younger than 16 years (median 5.3 years) and weighing at least 3 kg who underwent oral or nasal tracheal intubation using second generation Microcuff® PET between 2009 and 2015 were included. Of 13,219 oral tracheal intubations 12,049 (84.9%) were performed according to the manufacturer's size recommendation and 1170 with divergent endotracheal tubes. The odds ratio (OR) of oral reintubation was 0.13% (95% confidence interval 0.08-0.22%) for cases using the manufacture's size recommendation correctly and 22.74% (95% confidence interval 20.42-25.23%) for patients intubated with a not recommended tube (p < 0.0001).

Conclusion: These findings indicate that the second generation Microcuff® PETs can be reliably used with low tube exchange rates across the entire pediatric age range when the tube size is selected according to the manufacturer's size recommendation chart. Adherence to the manufacturer's tube size recommendation is urgently advised.

背景:与非套管气管插管相比,套管气管插管在儿科患者中具有较少需要再插管的潜在优势。本研究的目的是在一个大型的单一机构儿童队列中调查使用第二代Microcuff®儿童气管内管(PET)的换管率,并确定与换管风险升高相关的潜在变量。方法:回顾性分析从瑞士苏黎世大学儿童医院麻醉科电子患者资料管理系统获取的患者资料,包括人口统计学和人体测量学信息、用于正压通气的内管径大小以及与尺寸推荐表的差异。结果:数据来自14,188名年龄小于16岁(中位5.3岁),体重至少3 kg的儿童,他们在2009年至2015年期间使用第二代Microcuff®PET进行了口腔或鼻腔气管插管。在13219例口腔气管插管中,有12049例(84.9%)按照制造商推荐的尺寸进行插管,1170例采用气管导管发散。正确使用制造商推荐尺寸的患者口服再插管的优势比(OR)为0.13%(95%可信区间0.08-0.22%),而使用非推荐尺寸插管的患者的优势比(OR)为22.74%(95%可信区间20.42-25.23%)(p )。这些发现表明,第二代Microcuff®pet在整个儿科年龄范围内,当根据制造商的尺寸推荐表选择试管尺寸时,可以可靠地以低试管交换率使用。迫切建议遵守制造商的管尺寸建议。
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引用次数: 0
[Smart learning: 5 years (life)long]. 【智能学习:5年(终身)长】。
Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1007/s00101-024-01478-2
Jens C Kubitz
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引用次数: 0
[Publish in Die Anaesthesiologie : Open access through DEAL agreement, wide distribution through PubMed listing and tips for submission]. [发表在Die anaesiologie:通过DEAL协议开放获取,通过PubMed列表和提交提示广泛分发]。
Pub Date : 2024-12-01 DOI: 10.1007/s00101-024-01474-6
Ines Wolff, Rolf Rossaint, Bernhard Zwißler
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引用次数: 0
[The golden approach to trauma. Which blood products are needed for optimization of prehospital trauma care?] [治疗创伤的黄金方法。优化院前创伤护理需要哪些血液制品?]
Pub Date : 2024-12-01 Epub Date: 2024-11-18 DOI: 10.1007/s00101-024-01482-6
Maximilian Lothar Bamberg, Christian Grasshoff, Jessica Gerstner, Matthias Fabian Boos, Michael Bentele, Tim Viergutz, Johann Fontana, Peter Rosenberger, Robert Wunderlich

Background: The golden hour of trauma denotes the critical first hour after severe injury where timely medical response is crucial, although scientific support for this time frame is inconsistent. This study emphasizes optimizing trauma care by tailoring treatment to the specific injury rather than focusing solely on the speed of treatment. The aim is to document the need for improvement in prehospital trauma care, particularly by the use of blood and coagulation products.

Methods: After a pilot study, a purpose-designed online questionnaire targeted at German physicians and rescue service personnel was utilized to collect their views on general trauma care and specifically on the use of blood and coagulation products in prehospital settings. It also assessed the appropriateness of nine specific blood and coagulation products via a 5-point Likert scale. The percentages for each item were calculated for both physicians (n = 110) and rescue service personnel (n = 142) separately as well as an overall score to delineate patterns of agreement or disagreement.

Results: The study reached 9837 individuals, whereby 371 initially answered the questionnaire and 252 participants from Germany were finally included in the statistical analysis. The majority of both physicians (89.1%) and rescue service personnel (90.8%) agreed on the need to improve prehospital trauma care, particularly through the use of blood and coagulation products. Specifically, 60.9% of physicians and 83.8% of rescue personnel supported the prehospital administration of these products. Red blood cell concentrates and fibrinogen were notably endorsed, with 76.2% and 67.1% approval, respectively, for their potential to enhance survival in patients with significant blood loss; however, opinions varied on other blood products.

Conclusion: The data demonstrated a readiness to change the trauma approach and confirmed that effective options are available. The utilization of certain products is supported by existing research, underlining the need for their practical implementation in preclinical settings. Here, the emphasis shifts from the isolated time components to the quality of care delivered in an optimized time interval. Ideally, timely and high-quality care should complement each other, leveraging all available therapeutic resources. This could lead to the development of a golden approach to trauma to optimize outcomes in trauma care.

背景:创伤黄金一小时指的是严重受伤后的第一个小时,在这一关键时刻,及时的医疗响应至关重要,但科学界对这一时限的支持并不一致。本研究强调通过针对具体伤情的治疗来优化创伤护理,而不是仅仅关注治疗速度。目的是记录院前创伤救护中需要改进的地方,尤其是血液和凝血产品的使用:在试点研究之后,我们针对德国医生和救援服务人员设计了一份专门的在线调查问卷,以收集他们对一般创伤救护的看法,特别是对院前使用血液和凝血产品的看法。问卷还通过 5 点李克特量表评估了九种特定血液和凝血产品的适当性。对医生(n = 110)和救援服务人员(n = 142)分别计算了每个项目的百分比,并计算了总分,以确定同意或不同意的模式:这项研究的参与人数为 9837 人,其中 371 人初步回答了问卷,252 名来自德国的参与者最终被纳入统计分析。大多数医生(89.1%)和救援服务人员(90.8%)都认为有必要改善院前创伤护理,尤其是通过使用血液和凝血产品。具体来说,60.9% 的医生和 83.8% 的救援人员支持在院前使用这些产品。红细胞浓缩物和纤维蛋白原因可提高大量失血患者的存活率,分别得到76.2%和67.1%的认可;但对其他血液制品的意见不一:这些数据表明,人们愿意改变创伤治疗方法,并确认存在有效的选择。某些产品的使用得到了现有研究的支持,强调了在临床前环境中实际应用这些产品的必要性。在这里,重点从孤立的时间组成部分转移到在优化的时间间隔内提供的护理质量。理想情况下,及时治疗和高质量治疗应相辅相成,充分利用所有可用的治疗资源。这样就可以开发出一种治疗创伤的黄金方法,以优化创伤护理的效果。
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引用次数: 0
[Focus on sepsis and general intensive care medicine 2023-2024 : Summary of selected intensive medical care studies]. [2023-2024年脓毒症和普通重症监护医学聚焦:重症医学护理研究精选摘要]。
Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.1007/s00101-024-01456-8
C J Reuß, M Bernhard, C Beynon, M O Fiedler-Kalenka, A Hecker, C Jungk, C Nusshag, D Michalski, F C F Schmitt, T Brenner, M A Weigand, M Dietrich
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引用次数: 0
[Digital tools in residency and continuing medical education within the framework of a digital media concept]. [数字媒体概念框架下住院医师培训和继续医学教育中的数字工具]。
Pub Date : 2024-12-01 Epub Date: 2024-10-11 DOI: 10.1007/s00101-024-01466-6
Ulrike Schlüter, Ralf Sowa, Ingmar Finkenzeller, Thomas Mencke, Daniel A Reuter

There are currently many online resources for medical education during residency and beyond in anesthesiology, intensive care, pain, emergency and palliative medicine. From traditional textbooks and in-person events to learning platforms, apps, podcasts, simulation training and even virtual reality, there are many ways to supplement traditional residency curricula and continuing medical education. The coronavirus disease 2019 (COVID-19) pandemic has been instrumental in making medical education content more accessible and, among other things, accelerate the transfer of knowledge.To include all colleagues in the goal of life-long learning using these modern tools, we recommend the development of a digital media concept that is individually tailored to each department of anesthesiology. First, the goals of the department should be defined, e.g., can existing teaching materials be made more digitally accessible for asynchronous learning? Then, department resources should be compiled, e.g., what learning platforms are already being used and if and how social media should play a role? One or more persons should be named responsible and maintain the new concept. In this context, it is essential to develop quality criteria to properly assess the digital content.With the support of the department, conventional teaching methods can be combined with new digital possibilities in residency education and beyond. In this way, individual shift models, various levels of participation in live teaching events and different types of learners can be taken into account. These diverse digital tools can enrich the training and further education of every team member in an anesthesiology department and will accompany us well into the future.

目前,在麻醉学、重症监护、疼痛、急诊和姑息医学领域,有许多在线资源可用于住院实习期间及以后的医学教育。从传统的教科书和现场活动到学习平台、应用程序、播客、模拟训练甚至虚拟现实,有许多方法可以补充传统的住院医师课程和继续医学教育。2019 年冠状病毒病(COVID-19)大流行有助于使医学教育内容更易于获取,并加速知识的传播等。为了让所有同事都参与到利用这些现代工具进行终身学习的目标中来,我们建议制定一个数字媒体概念,为每个麻醉科量身定制。首先,应明确科室的目标,例如,现有的教学材料能否以更数字化的方式供异步学习使用?然后,应汇集科室资源,例如,已经在使用哪些学习平台,社交媒体是否应该发挥作用以及如何发挥作用?应指定一人或多人负责和维护这一新概念。在这种情况下,必须制定质量标准,以正确评估数字内容。在部门的支持下,可以将传统的教学方法与住院医师教育及其他方面的新数字可能性结合起来。通过这种方式,可以考虑到个人的转变模式、参与现场教学活动的不同程度以及不同类型的学习者。这些多样化的数字工具可以丰富麻醉科每个团队成员的培训和进修,并将伴随我们走向未来。
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引用次数: 0
[Cell salvage in obstetrics-Background and practical implementation]. [产科细胞抢救--背景和实际应用]。
Pub Date : 2024-12-01 DOI: 10.1007/s00101-024-01479-1
Mischa J Kotlyar, Vanessa Neef, Florian Rumpf, Patrick Meybohm, Kai Zacharowski, Peter Kranke

Postpartum hemorrhage (PPH) remains a leading cause of maternal mortality worldwide, with an increasing incidence in western countries over the past decades. During this period the numbers of PPH-related allogeneic red blood cell (RBC) transfusions have also significantly increased. Given the increasing scarcity and risks of allogeneic RBC transfusions, which are also associated with adverse maternal outcomes, optimized blood management strategies are urgently needed in obstetrics. In recent years, patient blood management (PBM) has been increasingly integrated into medical care, resulting in a significant improvement in patient outcomes. Cell salvage (CS) is one of the PBM blood-sparing techniques that enables the collection, processing and retransfusion of the patient's own blood during major bleeding events. Although recent evidence indicates that CS can significantly reduce the demand for allogeneic RBC transfusions and improve patient outcomes, the utilization in obstetrics in German hospitals remains low, with a usage rate of only 0.07% of births with peripartum hemorrhage. It must be assumed that concerns about patient-related complications, such as amniotic fluid embolism and maternal alloimmunization contribute to this hesitancy, alongside a lack of familiarity with the technique. This article provides an overview of the current evidence on the use and safety of CS in obstetrics. To facilitate a practical implementation, fundamental considerations and organizational precautions were prepared based on the experiences of the University Hospitals in Würzburg and Frankfurt and presented in the form of graphics and checklists for the perioperative use of CS during cesarean sections.

产后出血(PPH)仍然是全球孕产妇死亡的主要原因,过去几十年来,西方国家的发病率不断上升。在此期间,与 PPH 相关的异体红细胞(RBC)输血数量也显著增加。鉴于异体红细胞输血的稀缺性和风险日益增加,而且还与不良产妇结局相关,产科急需优化血液管理策略。近年来,患者血液管理(PBM)越来越多地融入医疗护理中,从而显著改善了患者的预后。细胞抢救(CS)是患者血液管理中的一项节血技术,可在大出血事件中收集、处理和再输患者自身的血液。尽管最近有证据表明,细胞挽救可以大大减少异体红细胞输血的需求并改善患者的预后,但在德国医院的产科中,细胞挽救的使用率仍然很低,仅占围产期出血新生儿的 0.07%。必须假设的是,对患者相关并发症的担忧(如羊水栓塞和母体同种异体免疫)以及对该技术的不熟悉是造成这种犹豫不决的原因。本文概述了产科中使用 CS 及其安全性的现有证据。为了便于实际操作,我们根据维尔茨堡和法兰克福大学医院的经验编写了基本注意事项和组织预防措施,并以图表和核对表的形式介绍了剖宫产手术围术期使用 CS 的情况。
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