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Evidence pyramid and artificial intelligence: a metamorphosis of clinical research 证据金字塔与人工智能:临床研究的蜕变
Pub Date : 2023-11-21 DOI: 10.1007/s44250-023-00050-w
Valentina Bellini, Enrico Ori, F. Coccolini, E. Bignami
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引用次数: 0
A systematic review of implementation reporting in opioid stewardship literature 阿片类药物管理文献中实施报告的系统综述
Pub Date : 2023-11-13 DOI: 10.1007/s44250-023-00054-6
Champika Pattullo, Benita Suckling, William Dace, Peter Donovan, Lisa Hall
Abstract Background The increased awareness of opioid-related harms has resulted in a proliferation of safety strategies and hospital-based quality improvement initiatives, often referred to as ‘opioid stewardship’ interventions. The effective translation of these interventions into more widespread practice relies on understanding and adapting important details of the implementation process. However, as with many healthcare quality improvement studies, the context, and details of the implementation are often absent from the published literature, limiting the scale and spread of practice. Aim To systematically review studies describing opioid stewardship interventions in acute hospital settings and assess the reporting of their implementation. Method A literature search of opioid stewardship interventions in MEDLINE/PubMed, EMBASE, Web of Science and the Cochrane Library from January 2000 to August 2020 was performed. We used Preferred Reporting Items for Systematic Reviews and Meta-analyses. Studies were screened initially for an evaluation of the intervention and subsequently for the inclusion of implementation reporting. The latter was coded using the four Normalisation Process Theory (NPT) domains. Results The database searches identified a total of 4031 publications, of which 372 underwent a full text review and 13 studies were included in the final analysis. The main reasons for exclusion during full-text review were insufficient details of the intervention (n = 90/354, 25%) or implementation (n = 215/354, 61%) to undergo an NPT analysis. When evaluating the potential for scale and spread of an intervention, all studies (n = 13) met the criteria for coherence, cognitive participation, and collective action, but only 3 reported on reflexive monitoring. Conclusion We identified only a small number of opioid stewardship studies that described the implementation processes of the reported interventions. This may be a barrier to effective translation of interventions into broader practice, limiting the potential for impact and benefit to patients and the wider community. Future studies of opioid stewardship interventions should consider using implementation science e.g., NPT across all aspects of knowledge translation and reporting.
背景:对阿片类药物相关危害的认识不断提高,导致了安全策略和医院质量改进举措的激增,通常被称为“阿片类药物管理”干预措施。将这些干预措施有效地转化为更广泛的实践依赖于理解和调整实施过程的重要细节。然而,与许多医疗保健质量改进研究一样,已发表的文献中往往缺少实施的背景和细节,限制了实践的规模和传播。目的系统回顾描述急性医院设置阿片类药物管理干预措施的研究,并评估其实施报告。方法检索2000年1月至2020年8月MEDLINE/PubMed、EMBASE、Web of Science和Cochrane Library中阿片类药物管理干预措施的文献。我们使用首选报告项目进行系统评价和荟萃分析。最初对研究进行筛选,以评估干预措施,随后纳入执行情况报告。后者使用四个规范化过程理论(NPT)域进行编码。结果数据库检索共发现4031篇出版物,其中372篇进行了全文审查,13篇研究被纳入最终分析。在全文审查中被排除的主要原因是干预措施的细节不足(n = 90/ 354,25%)或实施情况(n = 215/ 354,61%),无法进行NPT分析。在评估干预的规模和传播潜力时,所有研究(n = 13)都符合一致性、认知参与和集体行动的标准,但只有3项研究报告了反射性监测。结论:我们只发现了一小部分阿片类药物管理研究,这些研究描述了所报告的干预措施的实施过程。这可能是将干预措施有效转化为更广泛实践的障碍,限制了对患者和更广泛社区的影响和益处的潜力。阿片类药物管理干预措施的未来研究应考虑在知识转化和报告的所有方面使用实施科学,例如NPT。
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引用次数: 0
Meeting families in various social situations: reflections from healthcare staff working with an extended home-visiting program in Sweden 在不同的社会环境中与家庭会面:在瑞典从事延伸家访计划的医护人员的反思
Pub Date : 2023-11-10 DOI: 10.1007/s44250-023-00053-7
E. Mangrio, Maria Hjortsjö
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引用次数: 0
Addressing malaria incidence in Africa through health care expenditure and access to basic sanitation services 通过保健支出和获得基本卫生服务,解决非洲疟疾发病率问题
Pub Date : 2023-11-08 DOI: 10.1007/s44250-023-00052-8
Alfred Eboh, Aderonke Omotayo Adebayo
Abstract Background Malaria is a significant public health concern, particularly in sub-Saharan Africa. This study examined the impact of health care expenditure and access to basic sanitation services on malaria incidence in 28 selected African countries from 2000 to 2019. Methods The study was anchored on Health Production Function [HPF] model while General Panel Linear Model was adopted to examine the relationships between the variables. The retrospective research design was utilised. The statistical diagnostics tests were performed to check for multicollinearity, hereroskedasticity, normality and model specification using correlation matrix, Breusch Pagan/Cook Weisberg, Shapiro–Wilk and the Hausman specification. The hypotheses were tested at the 5% significance level and the analysis of the data was aided by the use of the STATA 13.0. Results Domestic Government General Health Expenditure [DGGHE] had a positive relationship with Malaria Incidence [MI], although it was not statistically significant [coefficient = 0.0454708, p -value = 0.604]. Out-Of-Pocket Health Expenditure [OOPHE] demonstrated a statistically significant positive association with MI [coefficient = 0.2839394, p -value = 0.009]. External Health Expenditure [EHE] showed a statistically significant negative relationship with MI [coefficient = − 0.1452344, p -value = 0.012]. Moreover, People using at least Basic Sanitation Services [PBSS] exhibited a statistically significant negative relationship with MI [coefficient = − 0.3854207, p -value = 0.000]. Conclusions The results suggested that while government health expenditure alone may not significantly impact malaria incidence, increased out-of-pocket expenditure and external health expenditure, as well as improved access to basic sanitation services, are associated with a higher likelihood of reducing malaria incidence in the selected African countries. Addressing malaria incidence in Africa requires a comprehensive approach that includes adequate government health care expenditure, reduction of out-of-pocket costs, increased external funding, and improved access to basic sanitation services. By implementing these recommendations, policymakers can make significant progress in reducing the burden of malaria and improving public health outcomes in affected African countries.
疟疾是一个重要的公共卫生问题,特别是在撒哈拉以南非洲地区。本研究调查了2000年至2019年选定的28个非洲国家的医疗保健支出和获得基本卫生服务对疟疾发病率的影响。方法采用健康生产函数(HPF)模型,采用一般面板线性模型检验各变量之间的关系。采用回顾性研究设计。采用相关矩阵、Breusch Pagan/Cook Weisberg、Shapiro-Wilk和Hausman规范进行统计诊断检验,以检查多重共线性、方差、正态性和模型规范。假设在5%显著性水平下进行检验,数据分析使用STATA 13.0辅助。结果国内政府一般卫生支出(DGGHE)与疟疾发病率(MI)呈正相关,但无统计学意义[系数= 0.0454708,p值= 0.604]。自费医疗支出(OOPHE)与心肌梗死呈显著正相关[系数= 0.2839394,p值= 0.009]。外部卫生支出(EHE)与心肌梗死呈显著负相关[系数= - 0.1452344,p值= 0.012]。此外,至少使用基本卫生服务(PBSS)的人口与MI呈统计学显著负相关[系数= - 0.3854207,p值= 0.000]。结果表明,虽然政府卫生支出本身可能不会显著影响疟疾发病率,但在选定的非洲国家,自费支出和外部卫生支出的增加以及基本卫生服务可及性的改善与降低疟疾发病率的可能性较高有关。解决非洲疟疾发病率问题需要采取综合办法,其中包括充足的政府保健支出、减少自付费用、增加外部资金和改善获得基本卫生服务的机会。通过实施这些建议,决策者可以在受影响非洲国家减轻疟疾负担和改善公共卫生成果方面取得重大进展。
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引用次数: 0
Know, comply, and live: the implications of protocols for COVID-19 management in sub-Saharan Africa 了解、遵守和生存:撒哈拉以南非洲地区COVID-19管理方案的影响
Pub Date : 2023-11-06 DOI: 10.1007/s44250-023-00042-w
Anthony Amoah
Abstract The aim of this study is to examine the factors influencing compliance with COVID-19 preventive management strategies in sub-Saharan Africa (SSA). To address the lack of national data associated with this study, a comprehensive cross-sectional panel dataset by GeoPoll, encompassing 12 SSA countries, is used. The study employs a novel index and a cross-sectional pooled logit econometric regression with predicted margins to identify the determinants of behavioural responses to COVID-19 management strategies. The findings reveal that demographic factors, institutional measures, and country-specific characteristics significantly impact compliance with COVID-19 management strategies in SSA. Additionally, a gender analysis of disaggregated COVID-19 pandemic management protocols revealed that females exhibit different compliance behaviours compared to males, specifically in relation to public transport, hygiene practices, handwashing, and social distancing. However, no significant gender differences are observed in behaviours such as avoiding public places and working from home. Surprisingly, the composite index, which measures overall compliance with all protocols, does not demonstrate any gender differences. Based on the findings, policies aimed at enhancing compliance should consider demographic, institutional, and country-specific factors while also accounting for gender differences in specific compliance behaviours.
摘要本研究旨在探讨撒哈拉以南非洲地区(SSA) COVID-19预防管理策略依从性的影响因素。为了解决缺乏与本研究相关的国家数据的问题,使用了GeoPoll的一个全面的横截面面板数据集,包括12个SSA国家。该研究采用了一种新的指数和具有预测边际的横截面混合logit计量经济回归,以确定对COVID-19管理策略的行为反应的决定因素。研究结果表明,人口因素、制度措施和国家具体特征显著影响SSA国家遵守COVID-19管理战略的情况。此外,对COVID-19大流行分类管理方案的性别分析显示,与男性相比,女性表现出不同的合规行为,特别是在公共交通、卫生习惯、洗手和保持社交距离方面。然而,在避免公共场所和在家工作等行为上,没有观察到明显的性别差异。令人惊讶的是,衡量所有协议总体遵守情况的综合指数并没有显示出任何性别差异。根据调查结果,旨在加强遵守的政策应考虑到人口、体制和国家具体因素,同时也考虑到具体遵守行为中的性别差异。
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引用次数: 0
Case history factors and audiological screening outcomes in HEU and HIV unexposed neonates at a district level hospital in Gauteng, South Africa 南非豪登省一家区级医院中HEU和HIV未暴露新生儿的病例史因素和听力学筛查结果
Pub Date : 2023-11-02 DOI: 10.1007/s44250-023-00049-3
Katijah Khoza-Shangase, Julia Nesbitt
Abstract While progress has been made in reducing vertical Mother to Child Transmission (MTCT) of HIV, limited research exists on the health needs of HIV-exposed uninfected (HEU) neonates, particularly in the field of audiology. This lack of research and evidence could impact early detection and intervention efforts. This study aimed to establish relationships and compare outcomes between case history factors and audiological screening results in HEU and HIV-unexposed neonates at a district-level hospital in Gauteng, South Africa. A non-experimental quantitative, descriptive, cross-sectional, comparative research design was employed. Data was collected with a sample size of 212 participants (100 HEU, 112 HIV-unexposed neonates) recruited using quota sampling. The hearing screening process involved case history assessment, medical file review, otoscopy, tympanometry testing, Distortion Product Evoked Otoacoustic Emissions (DPOAE), and Automated Auditory Brainstem Response (AABR) measurements. Descriptive and inferential statistics, including measures of central tendency and parametric tests, were used for data analysis. The findings indicated that 43% of HEU neonates exhibited refer findings on DPOAE, and 43% on AABR, compared to 26% and 25% respectively in the HIV-unexposed neonatal group. Therefore, a statistically significant relationship was established when comparing audiological results between the HEU and HIV-unexposed groups. Case history factors such as mode of delivery, birth weight, and Apgar scores were not associated with hearing loss in either group. However, in the HEU group, a higher proportion of participants referred on the overall screening in the maternal Retroviral Disease (RVD) stage IV group, although statistical significance was not established. This study fills an evidence gap regarding HEU neonates and highlights the need to include this vulnerable population in policy and clinical guidelines related to early hearing detection, intervention, and preventive audiology initiatives.
虽然在减少艾滋病毒母婴垂直传播(MTCT)方面取得了进展,但关于艾滋病毒暴露未感染(HEU)新生儿健康需求的研究有限,特别是在听力学领域。缺乏研究和证据可能会影响早期发现和干预工作。本研究旨在建立病例史因素与南非豪登省一家区级医院HEU和hiv未暴露新生儿听力学筛查结果之间的关系并比较其结果。采用非实验定量、描述性、横断面比较研究设计。数据收集的样本量为212名参与者(100名HEU, 112名未接触艾滋病毒的新生儿),采用配额抽样方法招募。听力筛查过程包括病史评估、医疗档案回顾、耳镜检查、鼓室测量、畸变产物诱发耳声发射(DPOAE)和自动听觉脑干反应(AABR)测量。数据分析采用描述性和推断性统计,包括集中趋势测量和参数检验。研究结果表明,43%的HEU新生儿在DPOAE和AABR方面表现出参考结果,而未暴露hiv的新生儿组分别为26%和25%。因此,当比较HEU和hiv未暴露组之间的听力学结果时,建立了统计学上显著的关系。两组的病史因素如分娩方式、出生体重和Apgar评分与听力损失无关。然而,在HEU组中,在母体逆转录病毒疾病(RVD) IV期组中接受总体筛查的参与者比例更高,尽管没有统计学意义。这项研究填补了关于新生儿高强度听力障碍的证据空白,并强调了将这一弱势群体纳入与早期听力检测、干预和预防性听力学倡议相关的政策和临床指南的必要性。
{"title":"Case history factors and audiological screening outcomes in HEU and HIV unexposed neonates at a district level hospital in Gauteng, South Africa","authors":"Katijah Khoza-Shangase, Julia Nesbitt","doi":"10.1007/s44250-023-00049-3","DOIUrl":"https://doi.org/10.1007/s44250-023-00049-3","url":null,"abstract":"Abstract While progress has been made in reducing vertical Mother to Child Transmission (MTCT) of HIV, limited research exists on the health needs of HIV-exposed uninfected (HEU) neonates, particularly in the field of audiology. This lack of research and evidence could impact early detection and intervention efforts. This study aimed to establish relationships and compare outcomes between case history factors and audiological screening results in HEU and HIV-unexposed neonates at a district-level hospital in Gauteng, South Africa. A non-experimental quantitative, descriptive, cross-sectional, comparative research design was employed. Data was collected with a sample size of 212 participants (100 HEU, 112 HIV-unexposed neonates) recruited using quota sampling. The hearing screening process involved case history assessment, medical file review, otoscopy, tympanometry testing, Distortion Product Evoked Otoacoustic Emissions (DPOAE), and Automated Auditory Brainstem Response (AABR) measurements. Descriptive and inferential statistics, including measures of central tendency and parametric tests, were used for data analysis. The findings indicated that 43% of HEU neonates exhibited refer findings on DPOAE, and 43% on AABR, compared to 26% and 25% respectively in the HIV-unexposed neonatal group. Therefore, a statistically significant relationship was established when comparing audiological results between the HEU and HIV-unexposed groups. Case history factors such as mode of delivery, birth weight, and Apgar scores were not associated with hearing loss in either group. However, in the HEU group, a higher proportion of participants referred on the overall screening in the maternal Retroviral Disease (RVD) stage IV group, although statistical significance was not established. This study fills an evidence gap regarding HEU neonates and highlights the need to include this vulnerable population in policy and clinical guidelines related to early hearing detection, intervention, and preventive audiology initiatives.","PeriodicalId":72826,"journal":{"name":"Discover health systems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating Years of Life Lost due to COVID-19 over the first two years of the pandemic in Cyprus: comparisons across areas, age, and sex 估计塞浦路斯疫情暴发头两年因COVID-19造成的生命损失年数:跨地区、年龄和性别的比较
Pub Date : 2023-11-02 DOI: 10.1007/s44250-023-00051-9
Periklis Charalampous, Juanita A. Haagsma, Sarah Cuschieri, Brecht Devleesschauwer, Sara M. Pires, Suzanne Polinder, Grant M. A. Wyper, Amalia Hatziyianni, Elena Pallari
Abstract Knowledge about the extent of the COVID-19 mortality burden is important to inform policy-making decisions. To gain greater insights into the population health impact of COVID-19 mortality, Years of Life Lost (YLL) can be estimated. We aimed to determine YLL linked to COVID-19 over the first two years (March 2020–March 2022) of the pandemic in Cyprus, by areas, and by age and sex. COVID-19 YLL was estimated by multiplying COVID-19 mortality counts by age-conditional life expectancy from the 2019 Global Burden of Disease life table. COVID-19 accounted for 16,704 YLL over the first two years of the pandemic—approximately 18.5 years lost per individual who died due to COVID-19 and 1881 YLL per 100,000 population. YLL per 100,000 was higher among males compared to females (2485 versus 1303 per 100,000) and higher among older than younger individuals. COVID-19 deaths and YLL per 100,000 were higher in high population-dense areas of Cyprus, such as Limassol. Continued evaluations of COVID-19 YLL are needed to inform on the proportionate population impact of COVID-19, over time and across areas of Cyprus.
了解COVID-19死亡率负担的程度对于为决策提供信息非常重要。为了更深入地了解COVID-19死亡率对人口健康的影响,可以估算生命损失年数。我们的目标是确定在塞浦路斯大流行的头两年(2020年3月至2022年3月),按地区、年龄和性别确定与COVID-19相关的YLL。COVID-19 - YLL是通过将2019年全球疾病负担生命表中的COVID-19死亡率乘以年龄条件下的预期寿命来估算的。在大流行的头两年,COVID-19造成了16,704 YLL的死亡,相当于每名因COVID-19死亡的人损失了大约18.5年的生命,每10万人损失了1881 YLL。每10万人中男性的YLL高于女性(每10万人中有2485人比1303人),老年人高于年轻人。在塞浦路斯利马索尔等人口密集地区,COVID-19死亡人数和每10万人中新增的新冠肺炎死亡率更高。需要继续对COVID-19 - YLL进行评估,以便了解COVID-19在塞浦路斯不同时间和不同地区对人口的影响。
{"title":"Estimating Years of Life Lost due to COVID-19 over the first two years of the pandemic in Cyprus: comparisons across areas, age, and sex","authors":"Periklis Charalampous, Juanita A. Haagsma, Sarah Cuschieri, Brecht Devleesschauwer, Sara M. Pires, Suzanne Polinder, Grant M. A. Wyper, Amalia Hatziyianni, Elena Pallari","doi":"10.1007/s44250-023-00051-9","DOIUrl":"https://doi.org/10.1007/s44250-023-00051-9","url":null,"abstract":"Abstract Knowledge about the extent of the COVID-19 mortality burden is important to inform policy-making decisions. To gain greater insights into the population health impact of COVID-19 mortality, Years of Life Lost (YLL) can be estimated. We aimed to determine YLL linked to COVID-19 over the first two years (March 2020–March 2022) of the pandemic in Cyprus, by areas, and by age and sex. COVID-19 YLL was estimated by multiplying COVID-19 mortality counts by age-conditional life expectancy from the 2019 Global Burden of Disease life table. COVID-19 accounted for 16,704 YLL over the first two years of the pandemic—approximately 18.5 years lost per individual who died due to COVID-19 and 1881 YLL per 100,000 population. YLL per 100,000 was higher among males compared to females (2485 versus 1303 per 100,000) and higher among older than younger individuals. COVID-19 deaths and YLL per 100,000 were higher in high population-dense areas of Cyprus, such as Limassol. Continued evaluations of COVID-19 YLL are needed to inform on the proportionate population impact of COVID-19, over time and across areas of Cyprus.","PeriodicalId":72826,"journal":{"name":"Discover health systems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome domains and measurement instruments of patient-relevant improvement of structure and processes as a new set of outcomes for evaluating and approving digital health applications: systematic review 与患者相关的结构和流程改进的结果域和测量工具作为评估和批准数字健康应用的一组新结果:系统审查
Pub Date : 2023-10-31 DOI: 10.1007/s44250-023-00046-6
Madlen Scheibe, Andreas Knapp, Lorenz Harst, Jochen Schmitt
Abstract Background In October 2020, digital health applications (DiGAs) became part of standard care in Germany. For approval, DiGA manufacturers must demonstrate medical benefit or patient-relevant improvement of structure and processes (PISP). PISP refers to an innovative outcome core area in terms of proof of benefits and reimbursement decisions. These are subdivided into 9 outcome domains, including for example health literacy, facilitating access to care, and coping with illness-related difficulties in everyday life. Their implementation aims at empowering patients, encouraging shared decision-making, and increasing patient-centeredness in healthcare delivery. Given the novelty of PISP, no standardized set of outcomes and outcome measurement instruments currently exists to operationalize the domains. Learning from previous evaluation studies can help operationalize and standardize PISPs for evaluation studies of digital health applications. Therefore, we investigated the outcomes and outcome measurement instruments, used in controlled trials to assess DiGA-compliant applications, published before the Digital Health Applications Ordinance of April 2020. Methods We conducted a systematic review of studies published between 01/2015 and 04/2020, via MEDLINE and Embase, complemented by forward/backward searches. Controlled trials assessing interventions adhering to the definition of DiGA were eligible, if they applied a validated outcome measurement instrument, and if results were presented in German or English. Title-abstract screening, full-text screening, data extraction and narrative synthesis were conducted independently by two researchers. Results Out of 2,671 references identified, 6 studies collecting a total of 48 outcomes were included. 14 outcomes (29.2%) addressed PISP by using 13 different measurement instruments. The outcomes corresponded to 5 of 9 PISP outcome domains with health literacy being the most common (7/14, 50.0%). Conclusions This review provides an overview of the characteristics of PISPs used in previous evaluation studies of DiGA-compliant applications. It shows which outcomes and validated outcome measurement instruments can be used to measure PISP and where knowledge is still lacking. These results serve as a starting point for operationalizing and standardizing PISPs and help to increase the outcome measurement quality of PISPs.
2020年10月,数字健康应用(DiGAs)成为德国标准医疗的一部分。为了获得批准,DiGA制造商必须证明医疗效益或与患者相关的结构和流程改进(PISP)。PISP是指在福利证明和报销决定方面的创新成果核心领域。这些目标被细分为9个成果领域,例如包括卫生知识普及、促进获得保健以及应对日常生活中与疾病有关的困难。它们的实施旨在赋予患者权力,鼓励共同决策,并在医疗保健服务中增加以患者为中心。鉴于PISP的新颖性,目前还没有标准化的结果集和结果测量工具来操作这些领域。从以往的评估研究中学习,有助于实施数字健康应用评估研究的pisp并使其标准化。因此,我们调查了在对照试验中使用的结果和结果测量工具,以评估在2020年4月《数字健康应用条例》之前发布的符合diga的应用。方法通过MEDLINE和Embase对2015年1月至2020年4月间发表的研究进行系统综述,并辅以向前/向后检索。根据DiGA定义评估干预措施的对照试验是合格的,如果它们应用了有效的结果测量工具,并且结果以德语或英语呈现。题目摘要筛选、全文筛选、数据提取和叙事综合由两位研究者独立完成。结果在2671篇文献中,纳入了6项研究,共收集了48个结果。14个结果(29.2%)通过使用13种不同的测量仪器来解决PISP问题。结果与9个PISP结果域中的5个相对应,其中健康素养最为常见(7/14,50.0%)。本综述综述了在DiGA-compliant应用的先前评估研究中使用的pisp的特点。它显示了可以使用哪些结果和经过验证的结果测量工具来测量PISP,以及仍然缺乏知识的地方。这些结果可作为pisp实施和标准化的起点,并有助于提高pisp的结果测量质量。
{"title":"Outcome domains and measurement instruments of patient-relevant improvement of structure and processes as a new set of outcomes for evaluating and approving digital health applications: systematic review","authors":"Madlen Scheibe, Andreas Knapp, Lorenz Harst, Jochen Schmitt","doi":"10.1007/s44250-023-00046-6","DOIUrl":"https://doi.org/10.1007/s44250-023-00046-6","url":null,"abstract":"Abstract Background In October 2020, digital health applications (DiGAs) became part of standard care in Germany. For approval, DiGA manufacturers must demonstrate medical benefit or patient-relevant improvement of structure and processes (PISP). PISP refers to an innovative outcome core area in terms of proof of benefits and reimbursement decisions. These are subdivided into 9 outcome domains, including for example health literacy, facilitating access to care, and coping with illness-related difficulties in everyday life. Their implementation aims at empowering patients, encouraging shared decision-making, and increasing patient-centeredness in healthcare delivery. Given the novelty of PISP, no standardized set of outcomes and outcome measurement instruments currently exists to operationalize the domains. Learning from previous evaluation studies can help operationalize and standardize PISPs for evaluation studies of digital health applications. Therefore, we investigated the outcomes and outcome measurement instruments, used in controlled trials to assess DiGA-compliant applications, published before the Digital Health Applications Ordinance of April 2020. Methods We conducted a systematic review of studies published between 01/2015 and 04/2020, via MEDLINE and Embase, complemented by forward/backward searches. Controlled trials assessing interventions adhering to the definition of DiGA were eligible, if they applied a validated outcome measurement instrument, and if results were presented in German or English. Title-abstract screening, full-text screening, data extraction and narrative synthesis were conducted independently by two researchers. Results Out of 2,671 references identified, 6 studies collecting a total of 48 outcomes were included. 14 outcomes (29.2%) addressed PISP by using 13 different measurement instruments. The outcomes corresponded to 5 of 9 PISP outcome domains with health literacy being the most common (7/14, 50.0%). Conclusions This review provides an overview of the characteristics of PISPs used in previous evaluation studies of DiGA-compliant applications. It shows which outcomes and validated outcome measurement instruments can be used to measure PISP and where knowledge is still lacking. These results serve as a starting point for operationalizing and standardizing PISPs and help to increase the outcome measurement quality of PISPs.","PeriodicalId":72826,"journal":{"name":"Discover health systems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving community health volunteers’ knowledge on cervical cancer using dialogue-based training in rural Kisumu County 在基苏木县农村开展以对话为基础的培训,提高社区卫生志愿者对宫颈癌的认识
Pub Date : 2023-10-30 DOI: 10.1007/s44250-023-00047-5
Edwin Onyango Ochomo, David Masinde, Collins Ouma
Abstract Background The global burden of cervical cancer continue to rise with the low- and middle-income countries bearing the greatest burden. East Africa recorded about 54560 cases and 36497 deaths attributed to cervical cancer in 2020 with 5236 cases and 3211 deaths being reported annually. This high burden can be attributed to low screening rates and late diagnosis, which lead to undesirable outcomes. Kenya still has low screening rates with only 16.4% of the eligible women screened against the WHO target of 70% by 2030. Kisumu has a lower screening rate of about 5.7% according to KHIS 2019 data. This low screening rate is due to lack of proper community health education. We evaluated the effectiveness of dialogue-based training in improving community health volunteers’ (CHV) knowledge on cervical cancer in Nyando. Methods The study adopted a pre-and-post, longitudinal study design. The CHVs knowledge was assessed before and after the training. We calculated the proportion net change in the number of CHVs with improved knowledge after the intervention. Statistical significance was assessed at p ≤ 0.05. Results The pre-test mean score was 30.1%, this improved to 53.4% at post-test following the dialogue-based training of the CHVs. The knowledge on the various aspects: risk factors ( p < 0.0001), signs and symptoms ( p < 0.0001) and screening ( p < 0.0001) significantly improved at the post-test following the dialogue-based training. The overall score also significantly improved (p < 0.0001) following the training among the CHVs. Occupation ( p < 0.0001) was found to be significantly associated with knowledge on cervical cancer. Conclusion The CHVs’ knowledge was inadequate but significantly improved following the dialogue-based training.
全球宫颈癌负担持续上升,中低收入国家负担最重。2020年,东非录得约54560例宫颈癌病例和36497例死亡,每年报告5236例病例和3211例死亡。这种高负担可归因于低筛查率和晚期诊断,从而导致不良后果。肯尼亚的筛查率仍然很低,只有16.4%的合格妇女接受了筛查,而世卫组织的目标是到2030年达到70%。根据KHIS 2019年的数据,基苏木的筛查率较低,约为5.7%。这种低筛查率是由于缺乏适当的社区卫生教育。我们评估了以对话为基础的培训在提高尼扬多社区卫生志愿者(CHV)对宫颈癌知识方面的有效性。方法采用前后、纵向研究设计。在培训前后对chv知识进行评估。我们计算了干预后知识水平提高的chv人数的净变化比例。p≤0.05,差异有统计学意义。结果测试前平均得分为30.1%,在基于对话的chv培训后提高到53.4%。各方面的知识:风险因素(p <0.0001),体征和症状(p <0.0001)和筛选(p <0.0001)在基于对话的训练之后的后测试中显著提高。总体得分也显著提高(p <0.0001)。职业(p <0.0001)与对子宫颈癌的了解程度显著相关。结论在对话培训后,chv的知识水平有了明显提高。
{"title":"Improving community health volunteers’ knowledge on cervical cancer using dialogue-based training in rural Kisumu County","authors":"Edwin Onyango Ochomo, David Masinde, Collins Ouma","doi":"10.1007/s44250-023-00047-5","DOIUrl":"https://doi.org/10.1007/s44250-023-00047-5","url":null,"abstract":"Abstract Background The global burden of cervical cancer continue to rise with the low- and middle-income countries bearing the greatest burden. East Africa recorded about 54560 cases and 36497 deaths attributed to cervical cancer in 2020 with 5236 cases and 3211 deaths being reported annually. This high burden can be attributed to low screening rates and late diagnosis, which lead to undesirable outcomes. Kenya still has low screening rates with only 16.4% of the eligible women screened against the WHO target of 70% by 2030. Kisumu has a lower screening rate of about 5.7% according to KHIS 2019 data. This low screening rate is due to lack of proper community health education. We evaluated the effectiveness of dialogue-based training in improving community health volunteers’ (CHV) knowledge on cervical cancer in Nyando. Methods The study adopted a pre-and-post, longitudinal study design. The CHVs knowledge was assessed before and after the training. We calculated the proportion net change in the number of CHVs with improved knowledge after the intervention. Statistical significance was assessed at p ≤ 0.05. Results The pre-test mean score was 30.1%, this improved to 53.4% at post-test following the dialogue-based training of the CHVs. The knowledge on the various aspects: risk factors ( p < 0.0001), signs and symptoms ( p < 0.0001) and screening ( p < 0.0001) significantly improved at the post-test following the dialogue-based training. The overall score also significantly improved (p < 0.0001) following the training among the CHVs. Occupation ( p < 0.0001) was found to be significantly associated with knowledge on cervical cancer. Conclusion The CHVs’ knowledge was inadequate but significantly improved following the dialogue-based training.","PeriodicalId":72826,"journal":{"name":"Discover health systems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136023155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost efficiency of primary health care facilities in Ghana: stochastic frontier analysis 加纳初级卫生保健设施的成本效率:随机前沿分析
Pub Date : 2023-10-19 DOI: 10.1007/s44250-023-00044-8
Kwadwo Arhin, Eric Fosu Oteng-Abayie, Jacob Novignon
Abstract Primary health care (PHC) is a universally accepted key strategy to achieve universal health coverage (UHC) and Sustainable Development Goal 3 (SDG 3) due to its potential to produce a range of economic benefits through improved health outcomes, health quality, and health system efficiency. However, little evidence exists about the cost efficiency of primary health care facilities (PHCFs) in Sub-Saharan Africa. This study evaluates the cost efficiency of two main types of PHCFs in Ghana that are at the forefront of delivering PHC services to a greater proportion of the population: Community Health Centers (HCs) and Community-Based Health Planning Services (CHPS) compounds. The dataset we used for this study included 39 HCs and 55 CHPS facilities. Furthermore, it examines the factors that influence the cost efficiency of these facilities. The study applies the stochastic frontier analysis (SFA) technique to panel data. The estimated cost efficiency for HCs and CHPS is 61.6% and 85.8%, respectively. The study further revealed that facility size, medical staff density, and facility age are the main factors that explain the differences in the cost efficiency of PHCFs in Ghana. The study's policy recommendation is that the Ghana Health Service should consider utilizing modern technology such as telehealth and telemedicine to enhance access to PHC services for people living in hard-to-reach and densely populated communities. This strategic approach can significantly contribute to improving the cost-efficiency of PHCFs.
初级卫生保健(PHC)是一项被普遍接受的实现全民健康覆盖(UHC)和可持续发展目标3 (SDG 3)的关键战略,因为它有可能通过改善健康结果、卫生质量和卫生系统效率产生一系列经济效益。然而,关于撒哈拉以南非洲初级卫生保健设施(PHCFs)的成本效益的证据很少。本研究评估了加纳两种主要类型的初级保健中心的成本效益,这两种主要类型的初级保健中心在向更大比例的人口提供初级保健服务方面处于领先地位:社区卫生中心(HCs)和社区卫生计划服务中心(CHPS)。本研究使用的数据集包括39个hc和55个CHPS设施。此外,它还研究了影响这些设施成本效率的因素。本研究将随机前沿分析(SFA)技术应用于面板数据。卫生保健中心和CHPS的估计成本效率分别为61.6%和85.8%。该研究进一步表明,设施规模、医务人员密度和设施年龄是解释加纳初级保健中心成本效率差异的主要因素。该研究的政策建议是,加纳卫生服务局应考虑利用远程保健和远程医疗等现代技术,使生活在交通不便和人口稠密社区的人们更容易获得初级保健服务。这一战略方针可以大大有助于提高phcf的成本效益。
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引用次数: 0
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