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Analysis of moderate and severe traumatic brain injury associated with skull base fracture: a local tertiary center experience 与颅底骨折相关的中度和重度创伤性脑损伤分析:地方三级中心的经验
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-16 DOI: 10.1186/s41984-024-00325-1
Mahmoud Saad, Ali A. Mowafy, Ahmed M. Naser, Abdelaziz Abdalhamid Ismail, Ahmed Zaher, Samer Serag, Ibrahim Serag, Mostafa Shahein
Traumatic brain injury (TBI) is a major medical and social concern in developing countries. TBI-related morbidity and mortality statistics in Egypt are lacking and do not reflect the actual magnitude of the problem. To overview the incidence of moderate and severe head trauma in a heavily populated developing country and document the outcome of moderate and severe TBI associated with skull base fracture (SBF). Data of patients admitted to our center with moderate and severe TBI associated with skull base fracture (SBF) were reviewed in the period between January 2019 and March 2023. The most common type of trauma was road traffic accidents in 54.2% of the patients; 91.2% had Single SBF (middle cranial fossa fracture was predominant 58.5%). 25.5% had an initial GCS of ≤ 8. Periorbital ecchymosis was the most common presenting sign in 36.3%. The most frequent complication (37.3%) was pneumocephalus. The presence of skull base fracture inversely affected the Glasgow outcome scale extended GOSE (P = 0.001, r = 0.674). Higher initial GCS scores were positively correlated with good GOSE (GOSE) (P = 0.001, r =− 0.222). RTA represents a significant cause for moderate and severe TBI in young male population. SBF is associated with poor outcome in moderate and severe TBI. Higher initial GCS score was positively correlated with good GOSE. It is important to have an overview of different types of TBI in Egypt.
创伤性脑损伤(TBI)是发展中国家的一个主要医疗和社会问题。埃及缺乏与创伤性脑损伤相关的发病率和死亡率统计数据,无法反映问题的实际严重程度。本研究旨在概述一个人口众多的发展中国家中度和重度头部创伤的发病率,并记录与颅底骨折(SBF)相关的中度和重度创伤性脑损伤的结果。我们回顾了本中心在2019年1月至2023年3月期间收治的伴有颅底骨折(SBF)的中度和重度创伤性脑损伤患者的数据。54.2%的患者最常见的创伤类型为道路交通事故;91.2%的患者为单发SBF(中颅窝骨折占58.5%)。25.5%的患者初始GCS≤8。眶周瘀斑是最常见的症状,占 36.3%。最常见的并发症(37.3%)是气胸。颅底骨折的存在对格拉斯哥结果量表扩展 GOSE 有反向影响(P = 0.001,r = 0.674)。较高的初始 GCS 评分与良好 GOSE 呈正相关(P = 0.001,r =- 0.222)。在年轻男性人群中,RTA 是导致中度和重度创伤性脑损伤的一个重要原因。SBF与中度和重度创伤性脑损伤的不良预后有关。较高的初始 GCS 评分与良好的 GOSE 呈正相关。对埃及不同类型的创伤性脑损伤进行概述非常重要。
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引用次数: 0
Multidisciplinary team approach in management of anterior spinal dysraphism with unusual presentation: case series and surgical approach 多学科团队治疗表现异常的脊柱前路发育不良:病例系列和手术方法
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-16 DOI: 10.1186/s41984-024-00324-2
Abdelhakeem A. Essa, Doaa Wadie Maximous Dawoud, Mohamed Anwar, Hussein Elkhayat, Ismail Taha
To report our experience with three cases of anterior lumbosacral meningocele with our multidisciplinary team plan and perioperative management and surgical approach for each case. Anterior meningocele is a rare congenital form of spinal dysraphism that involves protrusion of the theca anteriorly into the retroperitoneal and presacral space through an anterior defect. Three cases with anterior meningocele at different spinal levels (lumbar and sacral) were operated at Neurosurgery Department at Assiut University hospital from June to November 2020 with multidisciplinary management plans that were tailored separately for each case. Anterior meningocele is a rare form of spinal dysraphism and a challenging congenital anomaly that requires proper diagnosis and selection of surgical approach. Our case series outlines the importance of multidisciplinary team approach for tailoring perioperative management and surgical approach with intraoperative important steps.
报告我们对三例腰骶部前路脑膜囊肿病例的经验,以及我们多学科团队对每例病例的计划、围手术期管理和手术方法。前路脑膜囊是一种罕见的先天性脊柱发育不良,是指椎弓根通过前方缺损向腹膜后和骶前间隙前方突出。2020 年 6 月至 11 月,阿苏特大学医院神经外科为三例不同脊柱水平(腰椎和骶椎)的前脑膜囊患者实施了手术,并为每个病例分别制定了多学科管理计划。前脑膜囊是一种罕见的脊柱发育不良,也是一种具有挑战性的先天性异常,需要正确诊断和选择手术方法。我们的系列病例概述了多学科团队方法对定制围手术期管理和手术方法以及术中重要步骤的重要性。
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引用次数: 0
Conventional and old endovascular techniques for vertebral aneurysms still work in the era of flow diversion 在血流分流时代,治疗椎体动脉瘤的传统和老式血管内技术依然有效
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-13 DOI: 10.1186/s41984-024-00317-1
Gaurav Chauhan, Vivek Singh, Surya Nandan Prasad, Rajendra V. Phadke, Zafar Neyaz
Endovascular management for vertebral artery dissecting aneurysms (VADA) is quite intricate which thereby necessitate different strategies per case. Our current study described various optimal strategies available for endovascular management of VADA other than flow diverter (FD). 14 Patients presented with acute SAH and 4 patients with symptoms of mass effect. VADA were classified in 3 groups, viz contralateral vertebral artery is dominant group A (n = 5), co-dominant group B (n = 8) or group C hypoplastic (n = 5). Group A and B (n = 13) was further subdivided into three subtypes depending on location of aneurysm with respect to posterior inferior cerebellar artery (PICA), aneurysm proximal to the PICA, type I (n = 5); involving the PICA, type II (n = 1); and distal to the pica, type III (n = 4). Treatment strategy varied with type whether deconstructive or reconstructive methods using stents and coils in different fashion. Preprocedural angiographic work up delineating the anatomical location of the aneurysm, contralateral vertebral artery dominancy and nearby perforator status along with location of PICA is imperative in selecting the safest and optimal endovascular therapy option.
椎动脉夹层动脉瘤(VADA)的血管内治疗非常复杂,因此需要针对不同病例采取不同的治疗策略。我们目前的研究描述了除血流分流器(FD)外,血管内治疗 VADA 的各种最佳策略。14 名患者表现为急性 SAH,4 名患者有肿块症状。VADA分为3组,即对侧椎动脉占优势的A组(5人)、共占优势的B组(8人)或C组发育不良的C组(5人)。根据动脉瘤与小脑后下动脉(PICA)的位置,A 组和 B 组(n = 13)又分为三个亚型:动脉瘤位于小脑后下动脉近端,I 型(n = 5);涉及小脑后下动脉,II 型(n = 1);位于小脑后下动脉远端,III 型(n = 4)。不同类型的患者采用的治疗策略也不尽相同,有的采用解构法,有的采用重建法,支架和线圈的使用方式也不尽相同。为了选择最安全、最佳的血管内治疗方案,必须在术前进行血管造影检查,确定动脉瘤的解剖位置、对侧椎动脉的优势、附近穿孔动脉的状态以及 PICA 的位置。
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引用次数: 0
Possible effects of lumbar stabilization surgery on sagittal alignment, disability and quality of life 腰椎稳定手术对矢状排列、残疾和生活质量的可能影响
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-12 DOI: 10.1186/s41984-024-00316-2
Kadirhan Doğan, Özgen Aydincak, Hüseyin Yiğit, Erdoğan Unur
In order to restore the individual's health in lumbar stabilization surgeries, it is aimed to bring the sagittal alignment closer to normal values, to eliminate the findings, and thus to increase the quality of life of the individual by reducing the disability level. The aim of this study is to measure the effects of lumbar region stabilization surgeries performed in our clinic on some angular values in the spine, disability and quality of life. Preoperative (preop) and postoperative (postop) radiographs of 30 individuals over the age of 40 who applied to our clinic with various lumbar region complaints and underwent lumbar stabilization surgery between the years 2020–2022 were taken. Lumbar lordosis, pelvic tilt, sacral slope and pelvic inclination angles were measured from the images obtained. The Visual Analog Scale was used to measure the pain of individuals, the Oswestry Disability Index to measure the disability level, and the Nottingham Health Profile questionnaire to measure the quality of life. Preop and postop data were analyzed with the SPSS 23.0 program and p < 0.05 was considered significant. The lumbar lordosis angles of individuals who underwent lumbar stabilization surgery approached normal values and the difference between preop–postop lumbar lordosis angle averages was significant (p < 0.05); It was observed that the harmony between the lumbar lordosis and pelvic inclination angles increased, the pain decreased and the difference between preop–postop pain values was significant (p < 0.05), disability levels decreased and quality of life increased. The decrease in the level of disability and the increase in the quality of life seen in individuals who underwent lumbar stabilization surgery were associated with the decrease in pain; The changes in angular values are considered to be clinically significant.
在腰椎稳定手术中,为了恢复患者的健康,目的是使矢状排列更接近正常值,消除发现的问题,从而通过降低残疾程度来提高患者的生活质量。本研究的目的是测量在本诊所进行的腰椎区域稳定手术对脊柱某些角度值、残疾和生活质量的影响。本研究采集了 2020-2022 年间因各种腰椎部位不适到本诊所就诊并接受腰椎稳定手术的 30 名 40 岁以上患者的术前(术前)和术后(术后)X 光片。根据获得的图像测量腰椎前凸、骨盆倾斜、骶骨斜度和骨盆倾斜角度。用视觉模拟量表测量患者的疼痛程度,用Oswestry残疾指数测量残疾程度,用诺丁汉健康档案问卷测量生活质量。术前和术后数据均使用 SPSS 23.0 程序进行分析,P < 0.05 为差异显著。接受腰椎稳定手术者的腰椎前凸角度接近正常值,术前与术后腰椎前凸角度平均值差异有学意义(P < 0.05);观察到腰椎前凸与骨盆倾斜角度的协调性增加,疼痛减轻,术前与术后疼痛值差异有学意义(P < 0.05),残疾程度减轻,生活质量提高。接受腰椎稳定手术的患者残疾程度的降低和生活质量的提高与疼痛的减轻有关;角度值的变化被认为具有临床意义。
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引用次数: 0
Role of intraoperative cranial ultrasonography in detection of residual brain lesions during surgery 术中头颅超声波检查在手术中检测残余脑损伤中的作用
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-12 DOI: 10.1186/s41984-024-00315-3
Mahmoud Ahmed Gomaa, Mohamed Ahmed Hussein, Mohamed Abdellatif Hussein, Ashraf Abdellatif Osman
The use of IOUS is increasingly common in recent neurosurgical practice. IOUS has become very valuable in neurosurgery. It plays a key role in the localization of space-occupying lesion location and decreasing operation time and hence improves both surgical efficiency and safety. Ultrasound is very useful in the determination of the lesion location, its most superficial portion, and in differentiation between solid tumors and cystic components. Intraoperative ultrasonography has a significant edge over the other intraoperative aids for image guidance in brain surgery, especially in terms of independence, cost, and adaptability to multiple different clinical scenarios. Ultrasound-based neuro-navigation is an easy-to-use, fast, and safe technique of real-time imaging for various neurosurgical procedures. We conclude that ultrasound-based neuro-navigation is an easy-to-use, fast, and safe technique of real-time imaging for various neurosurgical procedures.
在最近的神经外科实践中,IOUS 的使用越来越普遍。IOUS 在神经外科手术中已变得非常有价值。它在定位占据空间的病灶位置和缩短手术时间方面发挥了关键作用,从而提高了手术效率和安全性。超声波在确定病灶位置、最表浅部分以及区分实体瘤和囊性成分方面非常有用。与脑外科手术中的其他术中图像引导辅助工具相比,术中超声波成像技术具有明显的优势,尤其是在独立性、成本和对多种不同临床情况的适应性方面。基于超声波的神经导航是一种易于使用、快速、安全的实时成像技术,适用于各种神经外科手术。我们的结论是,基于超声波的神经导航是一种易于使用、快速、安全的实时成像技术,适用于各种神经外科手术。
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引用次数: 0
Indirect bypass surgery as a line of management of pediatric moyamoya disease 间接旁路手术是治疗小儿莫亚莫亚氏病的一种方法
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-10 DOI: 10.1186/s41984-024-00322-4
Mohamed Farouk, Ibrahim Mohamed El-Tantawy, Mohamed Ali Kassem, Ashraf Ezzeldein, Mostafa Mahmoud Nabeeh, Mohamed M. Elsherbini
Moyamoya disease (MMD) is a chronic, rare cerebrovascular disorder of unknown cause featured by extensive narrowing of the terminal internal carotid artery (ICA) and its main branches. As a compensatory mechanism, perforators dilate forming fragile collateral vessels that appear as an abnormal vascular network resembling ‘puff of smoke drifting in the air’ observed via angiography around stenotic area in the brain. The database of the current hospital was retrospectively studied. All patients with ischemic strokes owing to MMD treated with surgical revascularization between January 2015 and December 2022 were included. MMD was identified on catheter-based digital subtraction angiography (DSA) by the presence of stenosis at the terminal portions of both internal carotid arteries and the development of abnormal collateral “moyamoya vessels” around the base of the brain. Clinical, radiological and follow-up data were retrospectively analyzed. During the mentioned time window, nine patients were diagnosed with moyamoya disease among all pediatric patients with established diagnosis of ischemic stroke in our institute; six of them underwent surgery. Unilateral EDMS was performed in 5 cases (83.3%), while one patient (16.67%) underwent staged bilateral surgeries with no added neurological deficit. Indirect revascularization surgery for pediatric moyamoya-related stroke patients has high rates of reperfusion and promising outcomes.
莫亚莫亚病(MMD)是一种原因不明的慢性罕见脑血管疾病,其特征是颈内动脉(ICA)末端及其主要分支广泛狭窄。作为一种代偿机制,穿孔器扩张形成脆弱的侧支血管,通过脑血管造影术观察狭窄区域周围的异常血管网络,就像 "空中飘浮的烟雾"。我们对本医院的数据库进行了回顾性研究。所有在2015年1月至2022年12月期间接受手术血管重建治疗的因MMD导致的缺血性脑卒中患者均被纳入研究范围。通过导管数字减影血管造影术(DSA)确定MMD的条件是两侧颈内动脉末端存在狭窄,且脑底周围出现异常侧支 "moyamoya血管"。对临床、放射学和随访数据进行了回顾性分析。在上述时间段内,在我院所有确诊为缺血性脑卒中的儿童患者中,有9名患者被诊断为moyamoya病,其中6人接受了手术治疗。其中 5 例(83.3%)接受了单侧 EDMS 手术,1 例(16.67%)接受了双侧分期手术,但未增加神经功能缺损。小儿莫亚莫亚相关中风患者的间接血管再通手术再灌注率高,疗效良好。
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引用次数: 0
A comprehensive study of risk factors predicting hydrocephalus following decompressive craniectomy in traumatic brain injuries 预测脑外伤减压开颅术后脑积水风险因素的综合研究
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-05 DOI: 10.1186/s41984-024-00323-3
Vikrant Yadav, Anurag Sahu, Nityanand Pandey, Ravi Shankar Prasad, Manish Mishra, Ravi Shekhar Pradhan
Decompressive craniectomy [DC] is one of the leading armaments to lower refractory intracranial pressure. Post-DC hydrocephalus [PDCH] occurs in 11.9–36% of patients undergoing DCs for TBIs. Various theories have been given regarding pathophysiological mechanism of PDCH but remain dubious. Risk factors predicting PDCH still under research. Exact timeline regarding developmental process of PDCH remains undefined. This retrospective study was conducted on 422 patients who underwent DCs in our tertiary care trauma center over the period of one year. 60 patients out of 422 who developed PDCH were analyzed with respect to demographic variables and preoperative and postoperative risk factors. A total of 20 randomly selected patients, who underwent DCs but did not develop hydrocephalus, were selected and compared with patients who developed PDCH. Outcome analysis was done by dichotomizing the groups into independent and dependent groups. Among 422 patients undergoing DC, 14.21%[n = 60] developed PDCH. Younger [34.2 y vs 43.3 y, p = 0.0004] male age group was predominant in our study. Age [p = 0.021, multivariate analysis] and midline shift [p = 0.008, multivariate analysis] were significant preoperative predicting risk factors for PDCH. Interhemispheric hygroma [p = 0.031], brain bulge [ p = 0.008], and blood in postoperative scan [p = 0.029] were significant postoperative risk factors. Lower GCS score at admission [p = 0.0003], postoperative day 10 and at the time of establishment of PDCH were significantly predicted surgery to hydrocephalus time. Midline shift [p = 0.007] and thickness of interhemispheric hygroma [p = 0.021] were associated with poor outcome in patients with PDCH. Younger age group and presence of midline shift are significant preoperative predictors of PDCH. Blood in postoperative scan, interhemispheric hygroma and brain bulge in postoperative period are significant predictors for PDCH. Deterioration in GCS score in postoperative period following DC should be taken as high index of suspicion for developing PDCH.
减压开颅术(DC)是降低难治性颅内压的主要手段之一。因创伤性脑损伤而接受减压开颅术的患者中,有 11.9% 至 36% 会出现减压开颅术后脑积水 [PDCH]。关于 PDCH 的病理生理学机制有多种理论,但仍存在疑点。预测 PDCH 的风险因素仍在研究中。PDCH发展过程的确切时间表仍未确定。这项回顾性研究针对在我们的三级医疗创伤中心接受 DC 手术的 422 名患者,历时一年。研究分析了 422 例 PDCH 患者中的 60 例患者的人口统计学变量、术前和术后风险因素。此外,还随机抽取了 20 名接受 DC 但未出现脑积水的患者,并与出现 PDCH 的患者进行了比较。结果分析将两组患者分为独立组和依赖组。在 422 名接受 DC 的患者中,14.21%[n = 60]出现了 PDCH。在我们的研究中,年龄较小的男性[34.2 岁 vs 43.3 岁,p = 0.0004]占多数。年龄[p = 0.021,多变量分析]和中线移位[p = 0.008,多变量分析]是术前预测PDCH的重要风险因素。大脑半球间瘤体[p = 0.031]、脑膨出[p = 0.008]和术后扫描血迹[p = 0.029]是术后的重要危险因素。入院时[p = 0.0003]、术后第 10 天和建立 PDCH 时 GCS 评分较低,可显著预测手术至脑积水的时间。中线移位[p = 0.007]和大脑半球间瘤体厚度[p = 0.021]与 PDCH 患者的不良预后有关。年龄较小和中线移位是术前预测 PDCH 的重要因素。术后扫描中的血迹、大脑半球间血肿和脑膨出是预测 PDCH 的重要因素。DC 术后 GCS 评分的恶化应作为 PDCH 的高度怀疑指标。
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引用次数: 0
Antiepileptic medications in neurosurgical practice 神经外科实践中的抗癫痫药物
Q4 CLINICAL NEUROLOGY Pub Date : 2024-09-03 DOI: 10.1186/s41984-024-00318-0
Mohamed Fatah Allah Alsawy
One of the earliest medical disorders to be identified is epilepsy. Strange and diverse forms of therapy have been used throughout history. A cure has not been found despite the popularity of ointments, medications, magic, enemas, exorcism, spiritualism, surgical and physical, as well as behavioural therapies. There is a notable deficiency of current literature about the management of seizures and epilepsy in neurosurgical patients, despite the fact that neurosurgeons are enrolled in the prescription of antiepileptic drugs (AEDs) for the seizures especially in perioperative periods. Neurosurgeons scope of management of epilepsy usually involve patients with either traumatic brain injury, neoplasms, subarachnoid haemorrhages, and brain abscess and infection. Depending on when they began, post-craniotomy seizures are categorised into three categories: promptly (before 24 h), early (before 1 week), and late (after 1 week). One-third of seizures can occur within the first month after a craniotomy, usually within the first 3 days, even though the risk of seizures persists for several post-operative months. There are multiple generations of AEDs, and further research is required to settle a clear recommendation for each and every case of seizures especially for hard population like the neurosurgical patients.
癫痫是最早被发现的医学疾病之一。古往今来,人们一直在使用各种奇怪的治疗方法。尽管药膏、药物、魔术、灌肠、驱魔、灵修、手术和物理以及行为疗法广受欢迎,但仍未找到治愈的方法。尽管神经外科医生会开具抗癫痫药物(AEDs)治疗癫痫发作,尤其是在围手术期,但目前关于神经外科患者癫痫发作和癫痫管理的文献明显不足。神经外科医生的癫痫治疗范围通常包括脑外伤、肿瘤、蛛网膜下腔出血、脑脓肿和感染患者。根据发作开始的时间,开颅手术后癫痫发作可分为三类:及时(24 小时前)、早期(1 周前)和晚期(1 周后)。三分之一的癫痫发作可能发生在开颅手术后的头一个月内,通常是头三天内,尽管癫痫发作的风险会持续到术后几个月。目前有多代 AEDs,需要进一步研究才能为每一个癫痫发作病例(尤其是神经外科患者等高危人群)确定明确的建议。
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引用次数: 0
Surpass Evolve flow diverter in the treatment for complex wide neck ruptured internal carotid artery aneurysm: technical report of two cases with brief literature review Surpass Evolve 分流器在治疗复杂宽颈颈内动脉瘤破裂中的应用:两例病例的技术报告及简要文献综述
Q4 CLINICAL NEUROLOGY Pub Date : 2024-08-30 DOI: 10.1186/s41984-024-00320-6
Mohan Karki, Girish Rajpal
Treatment of complex wide neck internal carotid aneurysm is technically difficult with both surgical as well as endovascular therapy. In this study, we work with flow diverter device to construct vascular lumen which diverts the blood flow from aneurysm sac. We report on two patients with two complex wide neck ruptured aneurysms located in the internal carotid artery associated with two small aneurysms who presented with severe headache and vomiting. All aneurysms were treated with single Surpass Evolve flow diverter (SE-FD) placement. Post-procedural clinical and angiographic outcomes were evaluated This study shows that Surpass Evolve flow diverter is safe and validity for management of complex wide neck internal carotid artery aneurysm and able to terminate all blister aneurysms associated with the parent artery.
治疗复杂的颈内动脉瘤,无论是手术还是血管内治疗,在技术上都很困难。在这项研究中,我们使用血流分流装置来构建血管腔,从而分流动脉瘤囊的血流。我们报告了两名患者的病例,他们患有两个复杂的宽颈动脉瘤,分别位于颈内动脉和两个小动脉瘤,并伴有严重的头痛和呕吐。所有动脉瘤均采用单个 Surpass Evolve 分流器(SE-FD)置入术进行治疗。这项研究表明,Surpass Evolve分流器在治疗复杂的颈内动脉宽颈动脉瘤方面安全有效,并能终结与母动脉相关的所有水泡型动脉瘤。
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引用次数: 0
Predictive factors of facial nerve function after medium/large vestibular schwannoma surgery: relationships between time of surgery, dimensions and size of resection 中型/大型前庭裂孔瘤手术后面神经功能的预测因素:手术时间、尺寸和切除大小之间的关系
Q4 CLINICAL NEUROLOGY Pub Date : 2024-08-30 DOI: 10.1186/s41984-024-00319-z
Daniele Armocida, Alessandro Pesce, Silvia Ciarlo, Francesco Marzetti, Alessandro Frati, Antonio Santoro
Vestibular schwannomas (VS) are slowly growing tumor, deriving from the vestibular component of cranial nerve VIII. Primary treatment modalities include microsurgery, radiosurgery, a combination of microsurgery and radiosurgery, and conservative treatment. The management of VS is a matter of debate, particularly in case of small tumors (less than 2 cm in diameter size). We performed an institutional retrospective review of a consecutive series of 28 surgically treated patients suffering from VS, operated in our institution. Patients were assigned on the ground of the preoperative imaging in two groups: tumors with major diameter of extra-meatal portion measuring ≥ 3 cm (Group I, 16 patients) and tumors with major diameter < to 3 cm (Group II, 12 patients). The total amount of 18/28 patients were females; the average age was 60.1 years. The average duration of the preoperative symptoms was 25.2 months, while the average interval between the diagnosis and surgical treatment was 8.68 months. The average preoperative volume was, respectively, for Group I and II tumors of 14.35 cm3 and 3.73 cm3. Age was associated to the duration of the preoperative symptoms (r = − 364; p = 0.044), with the probability to develop a complication (p = 0.031) and preoperative low HB score (r = − 324; p = 0.040). The presence of hypoacusis as preoperative symptom was strongly associated to a lesser postoperative maximum diameter and smaller residual disease (p = 0.014). Group I had a significantly longer hospitalization period in respect to Group II (p = 0.001) that impacted negatively to postoperative performance status (r = 0.368, p = 0.042). We confirmed the strong association between age and size of the lesion and the clinical results, where larger lesions in older patients are more prone to complications than smaller in young patients. We found that the patients presenting hypoacusis at onset were associate to lesser preoperative FN impairment outlining a possible differential involvement of the CN related to the internal meatus. We also introduce the strong association of Koos grade with postoperative performance status, hospitalization and facial nerve functionality.
前庭分裂瘤(VS)是一种生长缓慢的肿瘤,来源于颅神经VIII的前庭部分。主要治疗方法包括显微外科手术、放射外科手术、显微外科手术和放射外科手术联合治疗以及保守治疗。VS 的治疗方法一直存在争议,尤其是对于小肿瘤(直径小于 2 厘米)。我们对在本院接受手术治疗的 28 例 VS 患者进行了回顾性研究。根据术前影像学检查结果,患者被分为两组:产道外部分肿瘤大直径≥3厘米(I组,16名患者)和大直径小于3厘米(II组,12名患者)。共有 18/28 名患者为女性,平均年龄为 60.1 岁。术前症状的平均持续时间为 25.2 个月,从确诊到手术治疗的平均间隔时间为 8.68 个月。I 组和 II 组肿瘤的术前平均体积分别为 14.35 立方厘米和 3.73 立方厘米。年龄与术前症状持续时间(r = - 364;p = 0.044)、并发症发生概率(p = 0.031)和术前低 HB 评分(r = - 324;p = 0.040)相关。术前出现听力减退症状与术后最大直径较小、残留病灶较小密切相关(p = 0.014)。第一组的住院时间明显长于第二组(p = 0.001),这对术后表现状况有负面影响(r = 0.368,p = 0.042)。我们证实了年龄和病灶大小与临床结果之间的密切联系,老年患者的病灶较大,比年轻患者的病灶较小,更容易出现并发症。我们发现,发病时出现听力减退的患者术前 FN 受损程度较轻,这说明与内肉眼相关的 CN 可能受到不同程度的影响。我们还介绍了 Koos 分级与术后表现状况、住院时间和面神经功能的密切关系。
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Egyptian journal of neurosurgery
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