Pub Date : 2024-04-16DOI: 10.1186/s41984-024-00279-4
Wael Abd Elrahman Ali Elmesallamy
The purpose of this study was to evaluate the ability of intraoperative ultrasound (IOUS) to differentiate the gross pathological features of brain mass lesions in comparison with preoperative imaging and confirmable histopathological results. A total of 365 patients were operated on for brain mass lesions removal from May 2017 to May 2022 under the guidance of intraoperative ultrasound with transducers 2.5–8 megahertz (MHZ). Ultrasound gross pathological findings were compared to the preoperative imaging and the confirmable histopathological results. Intraoperative ultrasound defined either internal or external gross pathological features of all brain mass lesions. The IOUS showed spontaneous enhancements of the brain abscess walls, which were equivalent to contrasted CT and MRI. Significantly large diameters were noted in the IOUS measurement of abscesses in comparison with CT and MRI (P = 0.001). The walls of the brain abscesses were significantly well defined in IOUS imaging in comparison with CT (P = 0.001) and equivalent to MRI. IOUS showed equivalent significance to CT and MRI in characterizing intra-parenchymal hematomas. Significantly large diameters were noted in the IOUS measurement of hematomas in comparison with CT and MRI (P = 0.001). IOUS showed significant definition of brain tumors in comparison with CT and MRI regarding tumor edge definition, tumor contours, necrosis, and cystic components (cystic definition, cystic multiplicity, cystic trabeculations, and cystic wall thickness) (P = 0.001). IOUS was equivalent to CT and MRI regarding intra-tumoral hematomas and brain edema. IOUS was equivalent to CT regarding calcification detection. The significant criteria for high-grade brain tumors versus low grade by IOUS were: P = 0.001 (necrosis, brain edema, rare calcifications, presence of cystic components, thick cystic walls, large diameter, hypo-echogenicity, and heterogeneity); P = 0.002 (cystic trabeculations); P = 0.005 (multiple cysts); and P = 0.03 (irregular contour). IOUS can characterize brain tumors and suspect specific and significant criteria for many types with great overlap. Intraoperative ultrasound has the ability to differentiate the gross pathological features of brain mass lesions in comparison with preoperative imaging and confirmable histopathological results.
{"title":"Gross pathology of brain mass lesions by intraoperative ultrasonography: a comparative study","authors":"Wael Abd Elrahman Ali Elmesallamy","doi":"10.1186/s41984-024-00279-4","DOIUrl":"https://doi.org/10.1186/s41984-024-00279-4","url":null,"abstract":"The purpose of this study was to evaluate the ability of intraoperative ultrasound (IOUS) to differentiate the gross pathological features of brain mass lesions in comparison with preoperative imaging and confirmable histopathological results. A total of 365 patients were operated on for brain mass lesions removal from May 2017 to May 2022 under the guidance of intraoperative ultrasound with transducers 2.5–8 megahertz (MHZ). Ultrasound gross pathological findings were compared to the preoperative imaging and the confirmable histopathological results. Intraoperative ultrasound defined either internal or external gross pathological features of all brain mass lesions. The IOUS showed spontaneous enhancements of the brain abscess walls, which were equivalent to contrasted CT and MRI. Significantly large diameters were noted in the IOUS measurement of abscesses in comparison with CT and MRI (P = 0.001). The walls of the brain abscesses were significantly well defined in IOUS imaging in comparison with CT (P = 0.001) and equivalent to MRI. IOUS showed equivalent significance to CT and MRI in characterizing intra-parenchymal hematomas. Significantly large diameters were noted in the IOUS measurement of hematomas in comparison with CT and MRI (P = 0.001). IOUS showed significant definition of brain tumors in comparison with CT and MRI regarding tumor edge definition, tumor contours, necrosis, and cystic components (cystic definition, cystic multiplicity, cystic trabeculations, and cystic wall thickness) (P = 0.001). IOUS was equivalent to CT and MRI regarding intra-tumoral hematomas and brain edema. IOUS was equivalent to CT regarding calcification detection. The significant criteria for high-grade brain tumors versus low grade by IOUS were: P = 0.001 (necrosis, brain edema, rare calcifications, presence of cystic components, thick cystic walls, large diameter, hypo-echogenicity, and heterogeneity); P = 0.002 (cystic trabeculations); P = 0.005 (multiple cysts); and P = 0.03 (irregular contour). IOUS can characterize brain tumors and suspect specific and significant criteria for many types with great overlap. Intraoperative ultrasound has the ability to differentiate the gross pathological features of brain mass lesions in comparison with preoperative imaging and confirmable histopathological results.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"305 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140615235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.1186/s41984-024-00291-8
Juan Sebastián Reyes Bello, Diego Fernando Castiblanco Varón, Jose Luis Rozo Saavedra, Claudia Marcela Restrepo Lugo, Juan Nicolas Perez Mendez, Luis Rafael Moscote Salazar
The clay-shoveler fracture, named after Australian clay shovelers from the 1930s, results from high-energy, repetitive pulling mechanisms and is commonly associated with shoveling or digging. This injury primarily affects the lower cervical and upper thoracic vertebrae, particularly the C7 and T1 vertebrae. The avulsion mechanism, caused by stress on the spinous processes, may lead to sudden, severe upper back pain, limiting the affected individual’s ability to work effectively. This report presents the case of a 27-year-old boiler operator who experienced persistent neck pain, which did not respond to conservative management. Imaging studies revealed a T1 spinous process fracture with associated soft tissue edema, diagnosed as a clay-shoveler fracture. Conventional treatment with a semirigid cervical collar, analgesia, and rest was administered, leading to a favorable outcome. The clay-shoveler fracture, though rare, should be considered in cases involving repetitive stress on the cervical and thoracic spine, especially in occupations that require heavy lifting. In most instances, conservative management proves effective in relieving pain and enabling recovery. Recognizing the clay-shoveler fracture is crucial for timely diagnosis and treatment. This case report underscores the occupational nature of the injury and its association with specific work activities. Further research and reporting of similar cases will contribute to a deeper understanding of this unusual fracture pattern, its risk factors, and optimal management strategies.
{"title":"The clay-shoveler’s fracture, a rare occupational injury in the modern era: a case report","authors":"Juan Sebastián Reyes Bello, Diego Fernando Castiblanco Varón, Jose Luis Rozo Saavedra, Claudia Marcela Restrepo Lugo, Juan Nicolas Perez Mendez, Luis Rafael Moscote Salazar","doi":"10.1186/s41984-024-00291-8","DOIUrl":"https://doi.org/10.1186/s41984-024-00291-8","url":null,"abstract":"The clay-shoveler fracture, named after Australian clay shovelers from the 1930s, results from high-energy, repetitive pulling mechanisms and is commonly associated with shoveling or digging. This injury primarily affects the lower cervical and upper thoracic vertebrae, particularly the C7 and T1 vertebrae. The avulsion mechanism, caused by stress on the spinous processes, may lead to sudden, severe upper back pain, limiting the affected individual’s ability to work effectively. This report presents the case of a 27-year-old boiler operator who experienced persistent neck pain, which did not respond to conservative management. Imaging studies revealed a T1 spinous process fracture with associated soft tissue edema, diagnosed as a clay-shoveler fracture. Conventional treatment with a semirigid cervical collar, analgesia, and rest was administered, leading to a favorable outcome. The clay-shoveler fracture, though rare, should be considered in cases involving repetitive stress on the cervical and thoracic spine, especially in occupations that require heavy lifting. In most instances, conservative management proves effective in relieving pain and enabling recovery. Recognizing the clay-shoveler fracture is crucial for timely diagnosis and treatment. This case report underscores the occupational nature of the injury and its association with specific work activities. Further research and reporting of similar cases will contribute to a deeper understanding of this unusual fracture pattern, its risk factors, and optimal management strategies.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endovascular treatment of the wide-necked aneurysm is still challenging. Temporary stent-assisted coiling (TSAC) was introduced to manage the ruptured wide-necked aneurysms to avoid the long-term use of dual antiplatelets as well as improving aneurysm filling with coils. Here, we reported a case of the coil entrapment into the stent device during TSAC for the treatment of a wide-necked large ruptured aneurysm. Patient presented with loss of consciousness following diffuse subarachnoid hemorrhage due to a wide-necked large aneurysm located in the left ICA bifurcation. During treatment of aneurysm with TSAC technique, the stent could not retrieve and re-sheath because of coil entrapment in the stent struts. Consequently, the stent was released by cutting the pushing wire at the puncture site. Entrapment of coils in the stent struts is a very rare technical complication of TSAC method. It is essential to be aware of this side effect and how to avoid.
{"title":"Coil entrapment in temporary stent-assisted coiling of wide-neck aneurysm: a case report","authors":"Farid Qoorchi Moheb Seraj, Feizollah Ebrahimnia, Sajjad Najafi, Mahla Esmaeilzadeh, Humain Baharvahdat","doi":"10.1186/s41984-024-00280-x","DOIUrl":"https://doi.org/10.1186/s41984-024-00280-x","url":null,"abstract":"Endovascular treatment of the wide-necked aneurysm is still challenging. Temporary stent-assisted coiling (TSAC) was introduced to manage the ruptured wide-necked aneurysms to avoid the long-term use of dual antiplatelets as well as improving aneurysm filling with coils. Here, we reported a case of the coil entrapment into the stent device during TSAC for the treatment of a wide-necked large ruptured aneurysm. Patient presented with loss of consciousness following diffuse subarachnoid hemorrhage due to a wide-necked large aneurysm located in the left ICA bifurcation. During treatment of aneurysm with TSAC technique, the stent could not retrieve and re-sheath because of coil entrapment in the stent struts. Consequently, the stent was released by cutting the pushing wire at the puncture site. Entrapment of coils in the stent struts is a very rare technical complication of TSAC method. It is essential to be aware of this side effect and how to avoid.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-12DOI: 10.1186/s41984-024-00292-7
Kevin Pierre, U. George McCann, Seyedeh Mehrsa Sadat Razavi, Anjali Patel, Amanda Acevedo, John Cerillo, Abheek Raviprasad, Joseph Zhou, Dean Rashdan, Brandon Lucke-Wold
This review assesses laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgical oncology, emphasizing their utility in delineating tumor margins. Technologies such as optical coherence tomography, photoacoustic imaging, and confocal microscopy are scrutinized for their capability to enhance intraoperative discernment of neoplastic versus healthy tissue. We discuss the technical advancements, limitations related to depth penetration and resolution, and innovative approaches to mitigate these challenges. Economic and regulatory considerations pertinent to the clinical adoption of these technologies are also examined. The review highlights current clinical trials and research initiatives aiming to validate and standardize these applications. It concludes by highlighting the importance of ongoing research, cross-disciplinary cooperation, and professional training to integrate laser-based diagnostics into neurosurgical practice, with the ultimate goal of optimizing patient outcomes in brain tumor resection.
{"title":"Advances in laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgery: current practices and future perspectives","authors":"Kevin Pierre, U. George McCann, Seyedeh Mehrsa Sadat Razavi, Anjali Patel, Amanda Acevedo, John Cerillo, Abheek Raviprasad, Joseph Zhou, Dean Rashdan, Brandon Lucke-Wold","doi":"10.1186/s41984-024-00292-7","DOIUrl":"https://doi.org/10.1186/s41984-024-00292-7","url":null,"abstract":"This review assesses laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgical oncology, emphasizing their utility in delineating tumor margins. Technologies such as optical coherence tomography, photoacoustic imaging, and confocal microscopy are scrutinized for their capability to enhance intraoperative discernment of neoplastic versus healthy tissue. We discuss the technical advancements, limitations related to depth penetration and resolution, and innovative approaches to mitigate these challenges. Economic and regulatory considerations pertinent to the clinical adoption of these technologies are also examined. The review highlights current clinical trials and research initiatives aiming to validate and standardize these applications. It concludes by highlighting the importance of ongoing research, cross-disciplinary cooperation, and professional training to integrate laser-based diagnostics into neurosurgical practice, with the ultimate goal of optimizing patient outcomes in brain tumor resection.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In patients with spinal cord compression behind the cervical vertebra who presented with myelopathy, one of the treatment modalities is anterior cervical corpectomy followed by insertion of graft or implant. Autogenous bone graft has been the choice of implant for corpectomy in the past, but due to donor site complications, it has been majorly replaced with other implants like titanium made expandable and non-expandable cages. Studies on titanium made implants for cervical compressive myelopathy have mostly focused on expandable cages with separate plates. Studies on hybrid cages and winged expandable titanium cages with (WETC) are lacking, especially in patients with poor Nurick grade. Here, we present clinical outcomes and side effects of WETC use following cervical corpectomy in 81 participants from a tertiary care center from Eastern India with 6 months of follow-up. We observed a considerable improvement in clinical outcomes which was measured using Nurick grade as mean scores changed from 4.06 ± 0.85 during the pre-operative stage to 2.85 ± 1.16 post-operation (P < 0.05). There was also a considerable improvement in the pain status as in the pre-operative stage there were three patients with mild pain, 53 with moderate and 25 with severe pain, but post-operation there were 53 patients with mild pain, only two with moderate pain and none with severe pain (P < 0.00001). In these participants, we observed that post-surgical Nurick grade was not associated with age, gender or time since first symptoms but was strongly associated with pre-surgical Nurick grade at P < 0.05. With WETC (in situ plate), we were able to obtain good outcomes with less serious complication in patients with poor Nurick grade. As size of implant is prefixed and can be expanded in WETC, it takes relatively less time to insert, thus leading to shorter operative time. With good endplate preparation and avoiding over expansion of cage, WETC avoids complications.
{"title":"Outcome associated with use of winged expandable titanium cage following cervical corpectomy: an institutional experience","authors":"Anand Prakash, Rohit Bharti, Ganesh Chauhan, Gautam Dutta, Chandra Bhushan Sahay","doi":"10.1186/s41984-024-00288-3","DOIUrl":"https://doi.org/10.1186/s41984-024-00288-3","url":null,"abstract":"In patients with spinal cord compression behind the cervical vertebra who presented with myelopathy, one of the treatment modalities is anterior cervical corpectomy followed by insertion of graft or implant. Autogenous bone graft has been the choice of implant for corpectomy in the past, but due to donor site complications, it has been majorly replaced with other implants like titanium made expandable and non-expandable cages. Studies on titanium made implants for cervical compressive myelopathy have mostly focused on expandable cages with separate plates. Studies on hybrid cages and winged expandable titanium cages with (WETC) are lacking, especially in patients with poor Nurick grade. Here, we present clinical outcomes and side effects of WETC use following cervical corpectomy in 81 participants from a tertiary care center from Eastern India with 6 months of follow-up. We observed a considerable improvement in clinical outcomes which was measured using Nurick grade as mean scores changed from 4.06 ± 0.85 during the pre-operative stage to 2.85 ± 1.16 post-operation (P < 0.05). There was also a considerable improvement in the pain status as in the pre-operative stage there were three patients with mild pain, 53 with moderate and 25 with severe pain, but post-operation there were 53 patients with mild pain, only two with moderate pain and none with severe pain (P < 0.00001). In these participants, we observed that post-surgical Nurick grade was not associated with age, gender or time since first symptoms but was strongly associated with pre-surgical Nurick grade at P < 0.05. With WETC (in situ plate), we were able to obtain good outcomes with less serious complication in patients with poor Nurick grade. As size of implant is prefixed and can be expanded in WETC, it takes relatively less time to insert, thus leading to shorter operative time. With good endplate preparation and avoiding over expansion of cage, WETC avoids complications.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.1186/s41984-024-00286-5
Muhammed Erkam Yuksek, Busra Gul, Mehmet Kenan, Mehmet Fatih Erdi, Seyfullah Yıldırım, Ahmet Onder Guney, Fatih Keskin
In arteriovenous malformations, endovascular embolization was first used in the 1960s to occlude feeding vessels. In recent years, the success of endovascular treatments has increased. Thus, the use of endovascular therapy in the treatment of arteriovenous malformation has become widespread. Recently, it is the primary treatment method or an adjunctive treatment to surgery. The development of intracranial abscess after endovascular treatment with a liquid embolizing agent has been reported very rarely in the literature. In this article, a case of intracerebral abscess that developed after endovascular treatment with a liquid embolizing agent was presented. A 24-year-old male patient was admitted to the hospital with the complaints of dizziness and syncope. Arteriovenous malformation was observed in radiological imaging. Endovascular treatment for the AVM was performed. He was admitted to the hospital with similar complaints 2 months after the treatment. An abscess was observed around the AVM in the patient's cranial imaging. Infected materials in the mall were surgically removed, and the abscess was drained. After antibiotic treatment, the patient was discharged with full recovery. Due to the recent popularity of endovascular treatment methods, the incidence of abscess formation after embolization may change in the near future. Further research should be done to prevent this serious complication.
{"title":"Occipital abscess developed after endovascular AVM treatment with liquid embolizing agent: case report","authors":"Muhammed Erkam Yuksek, Busra Gul, Mehmet Kenan, Mehmet Fatih Erdi, Seyfullah Yıldırım, Ahmet Onder Guney, Fatih Keskin","doi":"10.1186/s41984-024-00286-5","DOIUrl":"https://doi.org/10.1186/s41984-024-00286-5","url":null,"abstract":"In arteriovenous malformations, endovascular embolization was first used in the 1960s to occlude feeding vessels. In recent years, the success of endovascular treatments has increased. Thus, the use of endovascular therapy in the treatment of arteriovenous malformation has become widespread. Recently, it is the primary treatment method or an adjunctive treatment to surgery. The development of intracranial abscess after endovascular treatment with a liquid embolizing agent has been reported very rarely in the literature. In this article, a case of intracerebral abscess that developed after endovascular treatment with a liquid embolizing agent was presented. A 24-year-old male patient was admitted to the hospital with the complaints of dizziness and syncope. Arteriovenous malformation was observed in radiological imaging. Endovascular treatment for the AVM was performed. He was admitted to the hospital with similar complaints 2 months after the treatment. An abscess was observed around the AVM in the patient's cranial imaging. Infected materials in the mall were surgically removed, and the abscess was drained. After antibiotic treatment, the patient was discharged with full recovery. Due to the recent popularity of endovascular treatment methods, the incidence of abscess formation after embolization may change in the near future. Further research should be done to prevent this serious complication.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140563381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Primary central nervous system melanoma is an extremely rare entity and even rarer in children and adolescents as compared to adults. It is often difficult to consider a diagnosis of intracranial melanoma pre-operatively without any clinical evidence of neurocutaneous melanosis. Herein, a case of primary melanoma of the brain is reported in a 17-year-old female who presented with headache, vomiting, and focal neurological deficit in the form of left-sided facial palsy and limb weakness. A contrast-enhanced computed tomography of head was performed which revealed a heterogeneously hyperattenuating mass lesion at left gangliocapsular region showing peripheral enhancement with internal non-enhancing cystic component. The patient underwent left frontotemporal craniotomy. The diagnosis was made on histopathological examination, which showed an invasive tumor comprising of epithelioid to spindled cells arranged in sheets, nests, and singly scattered. The special stains and immunohistochemical markers proved very helpful in establishing the diagnosis. The case highlights the uncommon occurrence of primary intracranial melanoma in the pediatric age group, the perplexing histological features, and the rapid and fatal course.
{"title":"Primary intracranial malignant melanoma in an adolescent female: a case report","authors":"Vikarn Vishwajeet, Pallavi Saraf, Poonam Abhay Elhence, Sarbesh Tiwari, Jaskaran Singh Gosal, Deepak Kumar Jha","doi":"10.1186/s41984-024-00287-4","DOIUrl":"https://doi.org/10.1186/s41984-024-00287-4","url":null,"abstract":"Primary central nervous system melanoma is an extremely rare entity and even rarer in children and adolescents as compared to adults. It is often difficult to consider a diagnosis of intracranial melanoma pre-operatively without any clinical evidence of neurocutaneous melanosis. Herein, a case of primary melanoma of the brain is reported in a 17-year-old female who presented with headache, vomiting, and focal neurological deficit in the form of left-sided facial palsy and limb weakness. A contrast-enhanced computed tomography of head was performed which revealed a heterogeneously hyperattenuating mass lesion at left gangliocapsular region showing peripheral enhancement with internal non-enhancing cystic component. The patient underwent left frontotemporal craniotomy. The diagnosis was made on histopathological examination, which showed an invasive tumor comprising of epithelioid to spindled cells arranged in sheets, nests, and singly scattered. The special stains and immunohistochemical markers proved very helpful in establishing the diagnosis. The case highlights the uncommon occurrence of primary intracranial melanoma in the pediatric age group, the perplexing histological features, and the rapid and fatal course.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.1186/s41984-024-00283-8
Majid Rezvani, Mehdi Mahmoodkhani, Soheil Fallahpour, Payman Rahmani, Hamed Koohgard, Donya Sheibani Tehrani
A disorder causes congenital kyphosis in the last stages of ossification and cartilage formation during embryonic development. The main treatment for this disease is surgery with various methods. The present study was performed to evaluate the results of the posterior surgery. This study was a descriptive study comparing the results before and after surgery which was performed in 2022 on 14 patients with the congenital kyphosis referred to Al-Zahra Hospital in Isfahan. Initial assessments were performed, and the patient underwent surgery. The patients were re-evaluated immediately after surgery which were followed up and evaluated two years after surgery. Data were collected by a checklist and described and analyzed in SPSS software version 22. The mean age of the patients was 23.15 ± 13.24 years, 7 patients (50%) were male, and the mean duration of surgery was 405.85 ± 123.99 min. Seven patients (50%) were under 18 years old. No disease died and the highest T12 involvement was in 5 patients (35.8%). Sagittal Vertical Axis, Kyphosis Angle and Lumbar Lordosis decreased in two stages immediately after surgery and follow-up, which were statistically significant (P < 0.05). No associated neurologic abnormalities was found during a physical examination or magnetic resonance imaging. In three phases (before, immediately after surgery, and follow-up), the mean of the Sagittal Vertical Axis, and Lumbar Lordosis in adults (over 18 years) and children (under 18 years) was not substantially different (P > 0.05). The mean Kyphosis Angle were significantly different in adults, and children at follow-up stages (P < 0.05). Because one of the children had a device filler in the follow-up stage. PSO can be used as a safe and effective technique to treat and correct Sagittal Vertical Axis, Kyphosis angle, Lumbar lordosis.
{"title":"Pedicle subtraction osteotomy in patient with congenital kyphosis","authors":"Majid Rezvani, Mehdi Mahmoodkhani, Soheil Fallahpour, Payman Rahmani, Hamed Koohgard, Donya Sheibani Tehrani","doi":"10.1186/s41984-024-00283-8","DOIUrl":"https://doi.org/10.1186/s41984-024-00283-8","url":null,"abstract":"A disorder causes congenital kyphosis in the last stages of ossification and cartilage formation during embryonic development. The main treatment for this disease is surgery with various methods. The present study was performed to evaluate the results of the posterior surgery. This study was a descriptive study comparing the results before and after surgery which was performed in 2022 on 14 patients with the congenital kyphosis referred to Al-Zahra Hospital in Isfahan. Initial assessments were performed, and the patient underwent surgery. The patients were re-evaluated immediately after surgery which were followed up and evaluated two years after surgery. Data were collected by a checklist and described and analyzed in SPSS software version 22. The mean age of the patients was 23.15 ± 13.24 years, 7 patients (50%) were male, and the mean duration of surgery was 405.85 ± 123.99 min. Seven patients (50%) were under 18 years old. No disease died and the highest T12 involvement was in 5 patients (35.8%). Sagittal Vertical Axis, Kyphosis Angle and Lumbar Lordosis decreased in two stages immediately after surgery and follow-up, which were statistically significant (P < 0.05). No associated neurologic abnormalities was found during a physical examination or magnetic resonance imaging. In three phases (before, immediately after surgery, and follow-up), the mean of the Sagittal Vertical Axis, and Lumbar Lordosis in adults (over 18 years) and children (under 18 years) was not substantially different (P > 0.05). The mean Kyphosis Angle were significantly different in adults, and children at follow-up stages (P < 0.05). Because one of the children had a device filler in the follow-up stage. PSO can be used as a safe and effective technique to treat and correct Sagittal Vertical Axis, Kyphosis angle, Lumbar lordosis.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-02DOI: 10.1186/s41984-024-00278-5
Mahmoud Saad, Hanee Ali, Ali A. Mowafy, Mohamed Badran, Ahmed Naguib Taha, Mohamed Mohsen Amen
To detect demographic, clinical, and radiological predictors of patient outcomes and prognosis in spontaneous cerebellar hematoma patients that may guide accurate decision making. This retrospective study was conducted on 45 patients with spontaneous cerebellar hematoma who underwent surgical treatment. The patient data including demographics (age, gender), preoperative consciousness at the time of admission, medical comorbidities (HTN, DM), radiological findings (location, volume, and diameter of the cerebellar hematoma, hydrocephalus, compression of the fourth ventricle, effacement of the quadrigeminal cistern, intraventricular hematoma, tight posterior fossa, and brain stem compression), and treatment methods were collected and correlated with prognosis. Outcome assessment was done using the Glasgow Outcome Scale (GOS), classified into good outcome (favorable result; GOS > 4) and poor outcome (unfavorable result; GOS < 4). There was a statistically significant correlation (p = 0.030) between the time to surgery and GOS, with more favorable outcomes in patients who underwent early surgery compared to late surgery. Unfavorable outcomes were detected in patients with higher Taneda grade and Kirollos grade, and both were statistically significant (p = 0.001). The presence of hydrocephalus and/or brainstem compression had a statistically significant (p < 0.001) negative impact on outcomes. Patients with extensive IVH had an unfavorable outcome compared to other patients (p = 0.016). The mortality rate in our study was 28.9%. Surgical management of spontaneous cerebellar hematoma is challenging. Many factors influence the appropriate decision making and surgical outcome. Predictors of an unfavorable outcome include the level of consciousness at admission, delayed time to surgery, a higher grade of 4th ventricular effacement (Kirollos) and quadrigeminal cistern effacement (Taneda), extensive IVH, hydrocephalus, and brainstem compression (statistically significant). There was no statistical significance regarding gender, age, hematoma volume, or hematoma diameter in relation to an unfavorable outcome.
{"title":"Surgical management of spontaneous posterior fossa hematoma: predictors of the neurological outcome","authors":"Mahmoud Saad, Hanee Ali, Ali A. Mowafy, Mohamed Badran, Ahmed Naguib Taha, Mohamed Mohsen Amen","doi":"10.1186/s41984-024-00278-5","DOIUrl":"https://doi.org/10.1186/s41984-024-00278-5","url":null,"abstract":"To detect demographic, clinical, and radiological predictors of patient outcomes and prognosis in spontaneous cerebellar hematoma patients that may guide accurate decision making. This retrospective study was conducted on 45 patients with spontaneous cerebellar hematoma who underwent surgical treatment. The patient data including demographics (age, gender), preoperative consciousness at the time of admission, medical comorbidities (HTN, DM), radiological findings (location, volume, and diameter of the cerebellar hematoma, hydrocephalus, compression of the fourth ventricle, effacement of the quadrigeminal cistern, intraventricular hematoma, tight posterior fossa, and brain stem compression), and treatment methods were collected and correlated with prognosis. Outcome assessment was done using the Glasgow Outcome Scale (GOS), classified into good outcome (favorable result; GOS > 4) and poor outcome (unfavorable result; GOS < 4). There was a statistically significant correlation (p = 0.030) between the time to surgery and GOS, with more favorable outcomes in patients who underwent early surgery compared to late surgery. Unfavorable outcomes were detected in patients with higher Taneda grade and Kirollos grade, and both were statistically significant (p = 0.001). The presence of hydrocephalus and/or brainstem compression had a statistically significant (p < 0.001) negative impact on outcomes. Patients with extensive IVH had an unfavorable outcome compared to other patients (p = 0.016). The mortality rate in our study was 28.9%. Surgical management of spontaneous cerebellar hematoma is challenging. Many factors influence the appropriate decision making and surgical outcome. Predictors of an unfavorable outcome include the level of consciousness at admission, delayed time to surgery, a higher grade of 4th ventricular effacement (Kirollos) and quadrigeminal cistern effacement (Taneda), extensive IVH, hydrocephalus, and brainstem compression (statistically significant). There was no statistical significance regarding gender, age, hematoma volume, or hematoma diameter in relation to an unfavorable outcome.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140562946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-11DOI: 10.1186/s41984-024-00273-w
Mohsin Fayaz, Azhar Khalid, Abrar Ahad Wani, Sajad Hussain Arif
A ventriculoperitoneal (VP) shunt is a cerebral shunt that diverts excess cerebrospinal fluid (CSF).Obstruction in the normal outflow or decreased absorption of the fluid is the usual cause. Hydrocephalus is treated by cerebral shunts.In paediatric patients, untreated hydrocephalus can be lethal and leads to many adverse effects including increase irritabilities, chronic headaches, learning difficulties, visual disturbances, and, in more advanced cases, severe mental retardation. Malfunction of the shunt with excess CSF accumulated can increase the intracranial pressure resulting in cerebral oedema and ultimately herniation. To study and evaluate the mechanical causes of shunt failure and their surgical remedies and reduce the preventable morbidity, cost and mortality associated with shunt failure. We conducted a prospective observational study including 70 patients who developed pure mechanical shunt failure for the first time from 2017 to 2020 in the Department of Neurosurgery Sher-i-kashmir Institute of Medical Sciences. Patients with previous shunt surgeries which include VP shunting and shunt revision or failure and shunt infections were excluded. Identity of all the patients has been kept anonymus. Written informed consent was obtained from all patients or their guardians in case of minors. Shunt malfunction was in the form of catheter misplacement, kinking, displacement from the ventricle or peritoneal cavity, disconnection, migration,inadvertent suturing of the catheter, air in shunt bulb. We found kinking at the proximal end in 25 (35%) patients as the most common cause of shunt failure. It was mostly as a result of inadequate and less spacious tunnelling made for the reservoir. Inadvertant suturing of shunt while closing abdomen in 7 (10%), shunt disconnection in 6 (8.5%), air in shunt bulb in 2 (2.8%), wrong placement at ventricular end in 10 (14.2%), shunt migration into the brain parenchyma in 5 (7.1%), shunt migration through the anal canal in 1(1.4%), pseudomeningocele around catheter valve in 3 (4.2%), placement of lower end into the preperitoneal space in 4 (5.7%) patients. Shunt surgery is seemingly a straightforward operation for neurosurgeons. But considering the incidence of shunt failure and its associated morbidity and mortality, it should always be done with trepidation and extreme caution. Exclusive mechanical shunt malfunction is a major concern and leads to great deal of morbidity in the shunt operations. However, there are trivial remedies and technical nuances which needs to be followed during surgery to avoid these complications.
{"title":"Mechanical shunt failure in hydrocephalus: a common but remediable complication with technical nuances","authors":"Mohsin Fayaz, Azhar Khalid, Abrar Ahad Wani, Sajad Hussain Arif","doi":"10.1186/s41984-024-00273-w","DOIUrl":"https://doi.org/10.1186/s41984-024-00273-w","url":null,"abstract":"A ventriculoperitoneal (VP) shunt is a cerebral shunt that diverts excess cerebrospinal fluid (CSF).Obstruction in the normal outflow or decreased absorption of the fluid is the usual cause. Hydrocephalus is treated by cerebral shunts.In paediatric patients, untreated hydrocephalus can be lethal and leads to many adverse effects including increase irritabilities, chronic headaches, learning difficulties, visual disturbances, and, in more advanced cases, severe mental retardation. Malfunction of the shunt with excess CSF accumulated can increase the intracranial pressure resulting in cerebral oedema and ultimately herniation. To study and evaluate the mechanical causes of shunt failure and their surgical remedies and reduce the preventable morbidity, cost and mortality associated with shunt failure. We conducted a prospective observational study including 70 patients who developed pure mechanical shunt failure for the first time from 2017 to 2020 in the Department of Neurosurgery Sher-i-kashmir Institute of Medical Sciences. Patients with previous shunt surgeries which include VP shunting and shunt revision or failure and shunt infections were excluded. Identity of all the patients has been kept anonymus. Written informed consent was obtained from all patients or their guardians in case of minors. Shunt malfunction was in the form of catheter misplacement, kinking, displacement from the ventricle or peritoneal cavity, disconnection, migration,inadvertent suturing of the catheter, air in shunt bulb. We found kinking at the proximal end in 25 (35%) patients as the most common cause of shunt failure. It was mostly as a result of inadequate and less spacious tunnelling made for the reservoir. Inadvertant suturing of shunt while closing abdomen in 7 (10%), shunt disconnection in 6 (8.5%), air in shunt bulb in 2 (2.8%), wrong placement at ventricular end in 10 (14.2%), shunt migration into the brain parenchyma in 5 (7.1%), shunt migration through the anal canal in 1(1.4%), pseudomeningocele around catheter valve in 3 (4.2%), placement of lower end into the preperitoneal space in 4 (5.7%) patients. Shunt surgery is seemingly a straightforward operation for neurosurgeons. But considering the incidence of shunt failure and its associated morbidity and mortality, it should always be done with trepidation and extreme caution. Exclusive mechanical shunt malfunction is a major concern and leads to great deal of morbidity in the shunt operations. However, there are trivial remedies and technical nuances which needs to be followed during surgery to avoid these complications.","PeriodicalId":72881,"journal":{"name":"Egyptian journal of neurosurgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140099617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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