首页 > 最新文献

Advances in Dental Research最新文献

英文 中文
Managing Carious Lesions: Consensus Recommendations on Terminology. 管理龋齿病变:术语的一致建议。
Q1 Medicine Pub Date : 2016-05-01 DOI: 10.1177/0022034516639276
N P T Innes, J E Frencken, L Bjørndal, M Maltz, D J Manton, D Ricketts, K Van Landuyt, A Banerjee, G Campus, S Doméjean, M Fontana, S Leal, E Lo, V Machiulskiene, A Schulte, C Splieth, A Zandona, F Schwendicke

Variation in the terminology used to describe clinical management of carious lesions has contributed to a lack of clarity in the scientific literature and beyond. In this article, the International Caries Consensus Collaboration presents 1) issues around terminology, a scoping review of current words used in the literature for caries removal techniques, and 2) agreed terms and definitions, explaining how these were decided.Dental cariesis the name of the disease, and thecarious lesionis the consequence and manifestation of the disease-the signs or symptoms of the disease. The termdental caries managementshould be limited to situations involving control of the disease through preventive and noninvasive means at a patient level, whereascarious lesion managementcontrols the disease symptoms at the tooth level. While it is not possible to directly relate the visual appearance of carious lesions' clinical manifestations to the histopathology, we have based the terminology around the clinical consequences of disease (soft, leathery, firm, and hard dentine). Approaches to carious tissue removal are defined: 1)selective removal of carious tissue-includingselective removal to soft dentineandselective removal to firm dentine; 2)stepwise removal-including stage 1,selective removal to soft dentine, and stage 2,selective removal to firm dentine6 to 12 mo later; and 3)nonselective removal to hard dentine-formerly known ascomplete caries removal(technique no longer recommended). Adoption of these terms, around managing dental caries and its sequelae, will facilitate improved understanding and communication among researchers and within dental educators and the wider clinical dentistry community.

用于描述龋齿病变临床管理的术语的变化导致科学文献和其他文献缺乏清晰度。在这篇文章中,国际龋齿共识合作提出了1)关于术语的问题,对文献中用于龋齿清除技术的当前词汇进行了范围审查,以及2)商定的术语和定义,并解释了这些术语和定义是如何确定的。龋齿是疾病的名称,而龋齿是疾病的后果和表现,即疾病的体征或症状。终末龋病管理应限于通过预防和非侵入性手段在患者层面控制疾病的情况,而龋病管理则是在牙齿层面控制疾病症状。虽然不可能将龋齿病变的临床表现与组织病理学直接联系起来,但我们已经根据疾病的临床后果(软质、革质、坚固和坚硬的牙本质)建立了术语。龋齿组织去除的方法定义为:1)选择性去除龋齿组织-包括选择性去除软牙本质和选择性去除坚固牙本质;2)逐步去除-包括第1阶段,选择性去除软质牙质,第2阶段,6至12个月后选择性去除硬质牙质;3)非选择性去除硬牙本质——以前称为完全除龋(不再推荐)。采用这些术语,围绕管理龋齿及其后遗症,将有助于增进研究人员之间、牙科教育工作者和更广泛的临床牙科社区之间的理解和交流。
{"title":"Managing Carious Lesions: Consensus Recommendations on Terminology.","authors":"N P T Innes,&nbsp;J E Frencken,&nbsp;L Bjørndal,&nbsp;M Maltz,&nbsp;D J Manton,&nbsp;D Ricketts,&nbsp;K Van Landuyt,&nbsp;A Banerjee,&nbsp;G Campus,&nbsp;S Doméjean,&nbsp;M Fontana,&nbsp;S Leal,&nbsp;E Lo,&nbsp;V Machiulskiene,&nbsp;A Schulte,&nbsp;C Splieth,&nbsp;A Zandona,&nbsp;F Schwendicke","doi":"10.1177/0022034516639276","DOIUrl":"https://doi.org/10.1177/0022034516639276","url":null,"abstract":"<p><p>Variation in the terminology used to describe clinical management of carious lesions has contributed to a lack of clarity in the scientific literature and beyond. In this article, the International Caries Consensus Collaboration presents 1) issues around terminology, a scoping review of current words used in the literature for caries removal techniques, and 2) agreed terms and definitions, explaining how these were decided.Dental cariesis the name of the disease, and thecarious lesionis the consequence and manifestation of the disease-the signs or symptoms of the disease. The termdental caries managementshould be limited to situations involving control of the disease through preventive and noninvasive means at a patient level, whereascarious lesion managementcontrols the disease symptoms at the tooth level. While it is not possible to directly relate the visual appearance of carious lesions' clinical manifestations to the histopathology, we have based the terminology around the clinical consequences of disease (soft, leathery, firm, and hard dentine). Approaches to carious tissue removal are defined: 1)selective removal of carious tissue-includingselective removal to soft dentineandselective removal to firm dentine; 2)stepwise removal-including stage 1,selective removal to soft dentine, and stage 2,selective removal to firm dentine6 to 12 mo later; and 3)nonselective removal to hard dentine-formerly known ascomplete caries removal(technique no longer recommended). Adoption of these terms, around managing dental caries and its sequelae, will facilitate improved understanding and communication among researchers and within dental educators and the wider clinical dentistry community. </p>","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 2","pages":"49-57"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034516639276","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34321377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 236
Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal. 管理龋齿病变:龋齿组织切除的共识建议。
Q1 Medicine Pub Date : 2016-05-01 DOI: 10.1177/0022034516639271
F Schwendicke, J E Frencken, L Bjørndal, M Maltz, D J Manton, D Ricketts, K Van Landuyt, A Banerjee, G Campus, S Doméjean, M Fontana, S Leal, E Lo, V Machiulskiene, A Schulte, C Splieth, A F Zandona, N P T Innes

The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of demineralized dentine. Dentists should manage the disease dental caries and control activity of existing cavitated lesions to preserve hard tissues and retain teeth long-term. Entering the restorative cycle should be avoided as far as possible. Controlling the disease in cavitated carious lesions should be attempted using methods which are aimed at biofilm removal or control first. Only when cavitated carious lesions either are noncleansable or can no longer be sealed are restorative interventions indicated. When a restoration is indicated, the priorities are as follows: preserving healthy and remineralizable tissue, achieving a restorative seal, maintaining pulpal health, and maximizing restoration success. Carious tissue is removed purely to create conditions for long-lasting restorations. Bacterially contaminated or demineralized tissues close to the pulp do not need to be removed. In deeper lesions in teeth with sensible (vital) pulps, preserving pulpal health should be prioritized, while in shallow or moderately deep lesions, restoration longevity becomes more important. For teeth with shallow or moderately deep cavitated lesions, carious tissue removal is performed according toselective removal to firm dentine.In deep cavitated lesions in primary or permanent teeth,selective removal to soft dentineshould be performed, although in permanent teeth,stepwise removalis an option. The evidence and, therefore, these recommendations support less invasive carious lesion management, delaying entry to, and slowing down, the restorative cycle by preserving tooth tissue and retaining teeth long-term.

国际龋齿共识协作组织进行了一个共识过程,并在此提出了龋齿组织去除和管理空化龋齿病变的临床建议,包括基于脱矿牙本质的修复。牙医应控制龋病和控制现有的空化病灶的活动,以保存硬组织和长期保留牙齿。应尽量避免进入恢复性周期。控制空洞性龋齿病变的方法应首先以去除或控制生物膜为目标。只有当空化的龋齿病变无法清洗或不能再密封时,才需要进行恢复性干预。当需要修复时,优先考虑的是:保持健康和可再矿化的组织,实现修复密封,保持牙髓健康,最大限度地提高修复成功率。去除龋齿组织纯粹是为了创造持久修复的条件。靠近牙髓的被细菌污染或脱矿的组织不需要移除。在牙体损伤较深且牙髓敏感(重要)的情况下,应优先考虑保持牙髓健康,而在牙体损伤较浅或中深的情况下,修复寿命则更为重要。对于有浅或中深空化病变的牙齿,根据选择性去除以稳固牙本质进行龋齿组织去除。对于乳牙或恒牙的深部空化病变,应选择性去除软牙本质,而对于恒牙,可选择逐步去除。因此,证据和这些建议支持较少侵入性的龋齿损害管理,通过保护牙齿组织和长期保留牙齿来延迟进入和减缓修复周期。
{"title":"Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal.","authors":"F Schwendicke,&nbsp;J E Frencken,&nbsp;L Bjørndal,&nbsp;M Maltz,&nbsp;D J Manton,&nbsp;D Ricketts,&nbsp;K Van Landuyt,&nbsp;A Banerjee,&nbsp;G Campus,&nbsp;S Doméjean,&nbsp;M Fontana,&nbsp;S Leal,&nbsp;E Lo,&nbsp;V Machiulskiene,&nbsp;A Schulte,&nbsp;C Splieth,&nbsp;A F Zandona,&nbsp;N P T Innes","doi":"10.1177/0022034516639271","DOIUrl":"https://doi.org/10.1177/0022034516639271","url":null,"abstract":"<p><p>The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of demineralized dentine. Dentists should manage the disease dental caries and control activity of existing cavitated lesions to preserve hard tissues and retain teeth long-term. Entering the restorative cycle should be avoided as far as possible. Controlling the disease in cavitated carious lesions should be attempted using methods which are aimed at biofilm removal or control first. Only when cavitated carious lesions either are noncleansable or can no longer be sealed are restorative interventions indicated. When a restoration is indicated, the priorities are as follows: preserving healthy and remineralizable tissue, achieving a restorative seal, maintaining pulpal health, and maximizing restoration success. Carious tissue is removed purely to create conditions for long-lasting restorations. Bacterially contaminated or demineralized tissues close to the pulp do not need to be removed. In deeper lesions in teeth with sensible (vital) pulps, preserving pulpal health should be prioritized, while in shallow or moderately deep lesions, restoration longevity becomes more important. For teeth with shallow or moderately deep cavitated lesions, carious tissue removal is performed according toselective removal to firm dentine.In deep cavitated lesions in primary or permanent teeth,selective removal to soft dentineshould be performed, although in permanent teeth,stepwise removalis an option. The evidence and, therefore, these recommendations support less invasive carious lesion management, delaying entry to, and slowing down, the restorative cycle by preserving tooth tissue and retaining teeth long-term. </p>","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 2","pages":"58-67"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034516639271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34321378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 334
Implant Surface Design Regulates Mesenchymal Stem Cell Differentiation and Maturation 植入物表面设计调节间充质干细胞分化和成熟
Q1 Medicine Pub Date : 2016-03-01 DOI: 10.1177/0022034515624444
B. Boyan, A. Cheng, R. Olivares-Navarrete, Z. Schwartz
Changes in dental implant materials, structural design, and surface properties can all affect biological response. While bulk properties are important for mechanical stability of the implant, surface design ultimately contributes to osseointegration. This article reviews the surface parameters of dental implant materials that contribute to improved cell response and osseointegration. In particular, we focus on how surface design affects mesenchymal cell response and differentiation into the osteoblast lineage. Surface roughness has been largely studied at the microscale, but recent studies have highlighted the importance of hierarchical micron/submicron/nanosurface roughness, as well as surface roughness in combination with surface wettability. Integrins are transmembrane receptors that recognize changes in the surface and mediate downstream signaling pathways. Specifically, the noncanonical Wnt5a pathway has been implicated in osteoblastic differentiation of cells on titanium implant surfaces. However, much remains to be elucidated. Only recently have studies been conducted on the differences in biological response to implants based on sex, age, and clinical factors; these all point toward differences that advocate for patient-specific implant design. Finally, challenges in implant surface characterization must be addressed to optimize and compare data across studies. An understanding of both the science and the biology of the materials is crucial for developing novel dental implant materials and surface modifications for improved osseointegration.
牙种植体材料、结构设计和表面特性的变化都会影响生物反应。虽然体积特性对种植体的机械稳定性很重要,但表面设计最终有助于骨整合。本文综述了有助于改善细胞反应和骨整合的牙种植材料的表面参数。我们特别关注表面设计如何影响间充质细胞的反应和向成骨细胞谱系的分化。表面粗糙度主要在微观尺度上进行研究,但最近的研究强调了分层微米/亚微米/纳米表面粗糙度的重要性,以及表面粗糙度与表面润湿性的结合。整合素是一种跨膜受体,可识别表面变化并介导下游信号通路。具体来说,非典型的Wnt5a通路与钛种植体表面细胞的成骨细胞分化有关。然而,仍有许多问题有待阐明。直到最近才对基于性别、年龄和临床因素的植入物的生物反应差异进行了研究;这些都指向了主张针对患者的植入物设计的差异。最后,必须解决种植体表面表征方面的挑战,以优化和比较研究中的数据。对材料的科学和生物学的理解对于开发新型牙种植材料和改善骨整合的表面修饰至关重要。
{"title":"Implant Surface Design Regulates Mesenchymal Stem Cell Differentiation and Maturation","authors":"B. Boyan, A. Cheng, R. Olivares-Navarrete, Z. Schwartz","doi":"10.1177/0022034515624444","DOIUrl":"https://doi.org/10.1177/0022034515624444","url":null,"abstract":"Changes in dental implant materials, structural design, and surface properties can all affect biological response. While bulk properties are important for mechanical stability of the implant, surface design ultimately contributes to osseointegration. This article reviews the surface parameters of dental implant materials that contribute to improved cell response and osseointegration. In particular, we focus on how surface design affects mesenchymal cell response and differentiation into the osteoblast lineage. Surface roughness has been largely studied at the microscale, but recent studies have highlighted the importance of hierarchical micron/submicron/nanosurface roughness, as well as surface roughness in combination with surface wettability. Integrins are transmembrane receptors that recognize changes in the surface and mediate downstream signaling pathways. Specifically, the noncanonical Wnt5a pathway has been implicated in osteoblastic differentiation of cells on titanium implant surfaces. However, much remains to be elucidated. Only recently have studies been conducted on the differences in biological response to implants based on sex, age, and clinical factors; these all point toward differences that advocate for patient-specific implant design. Finally, challenges in implant surface characterization must be addressed to optimize and compare data across studies. An understanding of both the science and the biology of the materials is crucial for developing novel dental implant materials and surface modifications for improved osseointegration.","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"10 - 17"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515624444","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 57
Integrative Performance Analysis of a Novel Bone Level Tapered Implant 新型骨水平锥形种植体的综合性能分析
Q1 Medicine Pub Date : 2016-03-01 DOI: 10.1177/0022034515624443
M. Dard, S. Kuehne, M. Obrecht, M. Grandin, J. Helfenstein, B. Pippenger
Primary mechanical stability, as measured by maximum insertion torque and resonance frequency analysis, is generally considered to be positively associated with successful secondary stability and implant success. Primary implant stability can be affected by several factors, including the quality and quantity of available bone, the implant design, and the surgical procedure. The use of a tapered implant design, for instance, has been shown to result in good primary stability even in clinical scenarios where primary stability is otherwise difficult to achieve with traditional cylindrical implants—for example, in soft bone and for immediate placement in extraction sockets. In this study, bone-type specific drill procedures are presented for a novel Straumann bone level tapered implant that ensure maximum insertion torque values are kept within the range of 15 to 80 Ncm. The drill procedures are tested in vitro using polyurethane foam blocks of variable density, ex vivo on explanted porcine ribs (bone type 3), and finally in vivo on porcine mandibles (bone type 1). In each test site, adapted drill procedures are found to achieve a good primary stability. These results are further translated into a finite element analysis model capable of predicting primary stability of tapered implants. In conclusion, we have assessed the biomechanical behavior of a novel taper-walled implant in combination with a bone-type specific drill procedure in both synthetic and natural bone of various types, and we have developed an in silico model for predicting primary stability upon implantation.
通过最大插入扭矩和共振频率分析测量的初级机械稳定性通常被认为与成功的二级稳定性和植入成功呈正相关。初级种植体的稳定性可受到几个因素的影响,包括可用骨的质量和数量、种植体的设计和手术程序。例如,使用锥形种植体设计,即使在传统圆柱形种植体难以达到初级稳定性的临床情况下,也显示出良好的初级稳定性,例如,在软骨中或立即放置在拔牙槽中。在本研究中,介绍了一种新型Straumann骨水平锥形种植体的骨类型特定钻孔程序,可确保最大插入扭矩值保持在15至80 Ncm的范围内。在体外使用变密度聚氨酯泡沫块对钻孔程序进行了测试,在离体猪排骨(骨型3)上进行了测试,最后在猪下颚(骨型1)上进行了体内测试。在每个测试点,发现适应的钻孔程序获得了良好的初步稳定性。这些结果进一步转化为能够预测锥形种植体初级稳定性的有限元分析模型。总之,我们已经评估了一种新型锥形壁种植体与不同类型的合成骨和天然骨的骨类型特定钻孔程序相结合的生物力学行为,并且我们已经开发了一个预测种植后初级稳定性的计算机模型。
{"title":"Integrative Performance Analysis of a Novel Bone Level Tapered Implant","authors":"M. Dard, S. Kuehne, M. Obrecht, M. Grandin, J. Helfenstein, B. Pippenger","doi":"10.1177/0022034515624443","DOIUrl":"https://doi.org/10.1177/0022034515624443","url":null,"abstract":"Primary mechanical stability, as measured by maximum insertion torque and resonance frequency analysis, is generally considered to be positively associated with successful secondary stability and implant success. Primary implant stability can be affected by several factors, including the quality and quantity of available bone, the implant design, and the surgical procedure. The use of a tapered implant design, for instance, has been shown to result in good primary stability even in clinical scenarios where primary stability is otherwise difficult to achieve with traditional cylindrical implants—for example, in soft bone and for immediate placement in extraction sockets. In this study, bone-type specific drill procedures are presented for a novel Straumann bone level tapered implant that ensure maximum insertion torque values are kept within the range of 15 to 80 Ncm. The drill procedures are tested in vitro using polyurethane foam blocks of variable density, ex vivo on explanted porcine ribs (bone type 3), and finally in vivo on porcine mandibles (bone type 1). In each test site, adapted drill procedures are found to achieve a good primary stability. These results are further translated into a finite element analysis model capable of predicting primary stability of tapered implants. In conclusion, we have assessed the biomechanical behavior of a novel taper-walled implant in combination with a bone-type specific drill procedure in both synthetic and natural bone of various types, and we have developed an in silico model for predicting primary stability upon implantation.","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"28 - 33"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515624443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
A Critical Perspective on Mechanical Testing of Implants and Prostheses 种植体和假体力学测试的关键观点
Q1 Medicine Pub Date : 2016-03-01 DOI: 10.1177/0022034515624445
E. Bonfante, Paulo G. Coelho, Paulo G. Coelho
The degree of interplay among variables in dental implant treatment presents a challenge to randomized clinical trials attempting to answer questions in a timely, unbiased, and economically feasible fashion. Further adding complexity to the different scenarios is the varied implant designs and related bone response, area of implantation, implant bulk material, restoration, abutments and related screws, fixation mode (screwed, fixed, or a combination), and horizontal implant-abutment matching geometry. This article critically appraises the most common mechanical testing methods used to characterize the implant-prostheses complex. It attempts to provide insight into the process of construction of an informed database of clinically relevant questions regarding preclinical evaluation of implant biomechanics and failure mechanisms. The use of single load to failure, fatigue life, fatigue limit, and step-stress accelerated life testing is discussed with emphasis on their deliverables, weaknesses, and strengths. Fractographic analysis and challenges in the correlation between laboratory- and in-service-produced failures of dental ceramics, resin composites, and titanium are introduced. In addition, examples are presented of mechanical characterization studies used in our laboratory to assess some implant-supported rehabilitation variables.
牙科种植体治疗中变量之间的相互作用程度对随机临床试验提出了挑战,这些试验试图以及时、公正和经济可行的方式回答问题。不同的种植体设计和相关的骨反应、种植面积、种植体体积材料、修复、基台和相关螺钉、固定模式(螺钉、固定或组合)以及水平种植体-基台匹配几何形状进一步增加了不同情况的复杂性。本文批判性地评价了用于表征种植体-假体复合物的最常见的机械测试方法。它试图提供深入了解关于临床前评估种植体生物力学和失效机制的临床相关问题的知情数据库的构建过程。讨论了单载荷失效、疲劳寿命、疲劳极限和阶跃应力加速寿命试验的使用,重点讨论了它们的可交付成果、弱点和优势。本文介绍了牙科陶瓷、树脂复合材料和钛材料的断口分析和实验室生产和实际生产失效之间的相关性。此外,还介绍了我们实验室用于评估一些种植体支持康复变量的机械表征研究的实例。
{"title":"A Critical Perspective on Mechanical Testing of Implants and Prostheses","authors":"E. Bonfante, Paulo G. Coelho, Paulo G. Coelho","doi":"10.1177/0022034515624445","DOIUrl":"https://doi.org/10.1177/0022034515624445","url":null,"abstract":"The degree of interplay among variables in dental implant treatment presents a challenge to randomized clinical trials attempting to answer questions in a timely, unbiased, and economically feasible fashion. Further adding complexity to the different scenarios is the varied implant designs and related bone response, area of implantation, implant bulk material, restoration, abutments and related screws, fixation mode (screwed, fixed, or a combination), and horizontal implant-abutment matching geometry. This article critically appraises the most common mechanical testing methods used to characterize the implant-prostheses complex. It attempts to provide insight into the process of construction of an informed database of clinically relevant questions regarding preclinical evaluation of implant biomechanics and failure mechanisms. The use of single load to failure, fatigue life, fatigue limit, and step-stress accelerated life testing is discussed with emphasis on their deliverables, weaknesses, and strengths. Fractographic analysis and challenges in the correlation between laboratory- and in-service-produced failures of dental ceramics, resin composites, and titanium are introduced. In addition, examples are presented of mechanical characterization studies used in our laboratory to assess some implant-supported rehabilitation variables.","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"18 - 27"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515624445","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 86
Clinical Relevance of Integrated Developmental Research for Dental Implants 牙种植体综合发育研究的临床意义
Q1 Medicine Pub Date : 2016-03-01 DOI: 10.1177/0022034516630947
M. Dard
The topic “clinical relevance of integrated developmental research for dental implants” was initially addressed at a multidisciplinary symposium during the 93rd General Session & Exhibition of the International Association for Dental Research on March 11, 2015, in Boston, Massachusetts, USA. The objective of this meeting consisted in discussing the optimal workflow for the development of a dental implant from the initial bench design to in vivo implantation at the clinical level. As a study case, attendees decided to share views on and confer about a new tapered implant. This special issue of Advances in Dental Research reflects the multiple outcomes of the discussions that took place during the above symposium and the multiple exchanges and chats that followed. The opening publication consists in a narrative review. The authors of the first paper, relying on undisputed clinical experience, describe that the relationship that exists among implant surface, primary stability, thread configuration, body shape, and type of bony bed has to be considered to lessen treatment times by decreasing the healing period during which osseointegration is established (Wilson et al. 2016). From this discussion, the concept of initial stability, which incorporates all the aforementioned parameters (including primary stability), clearly emerges. Consequently the 2 subsequent papers by Boyan et al. (2016) and Bonfante and Coelho (2016) deepen, respectively, the significance of implant surface and mechanical properties on osseointegration and their long-term maintenance. Boyan et al. (2016) insist on how surface design affects mesenchymal cell response and differentiation into the osteoblast lineage, as recent studies have highlighted the importance of hierarchical micro-/nanosurface roughness, as well as surface roughness in combination with surface wettability. Cell surface receptors recognize topographic and biological changes in the surface and downstream signaling pathways accordingly (i.e., the noncanonical Wnt5a pathway, which has been implicated in osteoblastic differentiation on titanium implant surfaces). Moreover, recently conducted studies on the differences in biological responses to implants based on sex, age, and clinical factors advocate for patient-specific implant designs. Bonfante and Coelho (2016) identify the complexity of investigating varied implant designs, related bone response, area of implantation, implant bulk material, restoration, abutments and related screws, fixation mode (screwed, fixed, or a combination), and horizontal implant-abutment matching geometry. They are concerned by the number of and interplay among variables in dental implant treatment and outline that this presents a challenge to clinical trials attempting to answer questions in a timely, unbiased, and economically feasible fashion. Their manuscript critically appraises the most common mechanical testing methods used to characterize the implant-prosthesis complex. It atte
2015年3月11日,在美国马萨诸塞州波士顿举行的第93届国际牙科研究协会大会暨展览会上,多学科研讨会首次讨论了“牙科种植体综合发展研究的临床意义”这一主题。本次会议的目的是讨论牙科种植体从最初的工作台设计到临床水平的体内种植的最佳工作流程。作为一个研究案例,与会者决定就一种新的锥形种植体分享意见并进行讨论。这期《牙科研究进展》特刊反映了在上述研讨会期间进行的讨论以及随后的多次交流和聊天的多种结果。开篇是一篇叙述性评论。第一篇论文的作者根据无可争议的临床经验,描述了必须考虑种植体表面、初级稳定性、螺纹配置、身体形状和骨床类型之间的关系,通过缩短骨整合建立的愈合时间来减少治疗时间(Wilson等人,2016)。从这个讨论中,包含上述所有参数(包括初级稳定性)的初始稳定性概念清晰地出现了。因此,Boyan et al.(2016)和Bonfante and Coelho(2016)随后的两篇论文分别深化了种植体表面和力学性能对骨整合及其长期维护的重要性。Boyan等人(2016)坚持认为,表面设计如何影响间充质细胞的反应和向成骨细胞谱系的分化,因为最近的研究强调了层次微/纳米表面粗糙度的重要性,以及表面粗糙度与表面润湿性的结合。细胞表面受体相应识别表面和下游信号通路的地形和生物学变化(即非规范的Wnt5a通路,它与钛种植体表面的成骨细胞分化有关)。此外,最近开展的关于基于性别、年龄和临床因素的植入物生物学反应差异的研究提倡针对患者的植入物设计。Bonfante和Coelho(2016)指出了研究不同种植体设计、相关骨反应、种植面积、种植体体积材料、修复、基台和相关螺钉、固定模式(螺钉、固定或组合)以及水平种植体-基台匹配几何形状的复杂性。他们关注种植牙治疗中变量的数量和相互作用,并概述这对临床试验提出了挑战,试图以及时、公正和经济可行的方式回答问题。他们的手稿批判性地评估了最常用的机械测试方法,用于表征种植体-假体复合物。它试图提供深入了解关于临床前评估种植体生物力学和失效机制的临床相关问题的知情数据库的构建过程。对单载荷失效试验、疲劳寿命试验、疲劳极限试验和阶梯应力加速寿命试验等方法的应用进行了实际讨论,并着重分析了它们的优缺点。Dard等人(2016)发表的第四篇论文为应用于新型骨水平锥形植入物的综合性能分析概念进行了辩护。他们建议依次进行骨类型特定的钻孔程序,以确保通过最大插入扭矩和共振频率分析测量的最大插入扭矩值在15至80 N·cm范围内。锥形壁种植体的生物力学行为是通过结合不同类型的天然骨(猪肋骨和下颌骨)的骨类型特异性钻孔程序和使用可变密度聚氨酯泡沫块(骨类型1至4)的体外模型来评估的。该方法旨在预测种植后的初步稳定性。此外,作者表明,有限元分析支持针对给定种植体类型和骨质量合并优化钻孔程序的有效性。Stavropoulos和Cochran (Stavropoulos等人,2016)通过在临床前体内模型中评估,与标准方案相比,涉及种植体部位轻微准备不足的方案是否会对骨整合方面产生影响,并对种植体截骨的边缘方面进行记录和分析,从而提供了广泛的结论性贡献。一半的植入物立即被加载,其余的被淹没。标准钻井方案组630947 ADRXXX10记录的平均插入扭矩值明显较低。 中国口腔医学研究进展,牙种植体综合发展研究- 2016
{"title":"Clinical Relevance of Integrated Developmental Research for Dental Implants","authors":"M. Dard","doi":"10.1177/0022034516630947","DOIUrl":"https://doi.org/10.1177/0022034516630947","url":null,"abstract":"The topic “clinical relevance of integrated developmental research for dental implants” was initially addressed at a multidisciplinary symposium during the 93rd General Session & Exhibition of the International Association for Dental Research on March 11, 2015, in Boston, Massachusetts, USA. The objective of this meeting consisted in discussing the optimal workflow for the development of a dental implant from the initial bench design to in vivo implantation at the clinical level. As a study case, attendees decided to share views on and confer about a new tapered implant. This special issue of Advances in Dental Research reflects the multiple outcomes of the discussions that took place during the above symposium and the multiple exchanges and chats that followed. The opening publication consists in a narrative review. The authors of the first paper, relying on undisputed clinical experience, describe that the relationship that exists among implant surface, primary stability, thread configuration, body shape, and type of bony bed has to be considered to lessen treatment times by decreasing the healing period during which osseointegration is established (Wilson et al. 2016). From this discussion, the concept of initial stability, which incorporates all the aforementioned parameters (including primary stability), clearly emerges. Consequently the 2 subsequent papers by Boyan et al. (2016) and Bonfante and Coelho (2016) deepen, respectively, the significance of implant surface and mechanical properties on osseointegration and their long-term maintenance. Boyan et al. (2016) insist on how surface design affects mesenchymal cell response and differentiation into the osteoblast lineage, as recent studies have highlighted the importance of hierarchical micro-/nanosurface roughness, as well as surface roughness in combination with surface wettability. Cell surface receptors recognize topographic and biological changes in the surface and downstream signaling pathways accordingly (i.e., the noncanonical Wnt5a pathway, which has been implicated in osteoblastic differentiation on titanium implant surfaces). Moreover, recently conducted studies on the differences in biological responses to implants based on sex, age, and clinical factors advocate for patient-specific implant designs. Bonfante and Coelho (2016) identify the complexity of investigating varied implant designs, related bone response, area of implantation, implant bulk material, restoration, abutments and related screws, fixation mode (screwed, fixed, or a combination), and horizontal implant-abutment matching geometry. They are concerned by the number of and interplay among variables in dental implant treatment and outline that this presents a challenge to clinical trials attempting to answer questions in a timely, unbiased, and economically feasible fashion. Their manuscript critically appraises the most common mechanical testing methods used to characterize the implant-prosthesis complex. It atte","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"2 - 3"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034516630947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Osteotomy Preparation on Osseointegration of Immediately Loaded, Tapered Dental Implants 截骨准备对即刻加载锥形种植体骨整合的影响
Q1 Medicine Pub Date : 2016-03-01 DOI: 10.1177/0022034515624446
Andreas Stavropoulos, David L. Cochran, M. Obrecht, B. Pippenger, Michel Dard
The aim of the present preclinical in vivo study was to evaluate whether a modified “drill-only” protocol, involving slight underpreparation of the implant site, may have an effect on aspects of osseointegration of a novel bone-level tapered implant, compared with the “standard drilling” protocol involving taping and profiling of the marginal aspect of the implant socket. In each side of the edentulated and completely healed mandible of 11 minipigs, 2 tapered implants (8 mm long × 4.1 mm Ø, BLT; Institut Straumann AG, Basel, Switzerland) were installed either with the drill-only or the standard drilling protocol. Significantly lower average insertion torque values were recorded for the standard drilling protocol group (52 ± 29 Ncm) compared with the drill-only group (70 ± 27 Ncm) (t test, P ≤ 0.05); no significant difference was observed between the 2 groups regarding implant stability, by means of resonance frequency analysis (75 ± 8 vs. 75 ± 6, respectively). Half of the implants were immediately loaded and the rest were submerged, providing observation times of 8 or 4 wk, respectively. Non-decalcified histological and histomorphometric analysis of the implants with surrounding tissues showed no significant differences between the 2 drilling protocols regarding the distance from the implant platform to the first coronal bone-to-implant contact (f-BIC), the total bone-to-implant contact (BIC) as a percentage of the total implant perimeter, and the bone density in an area extending 1 mm laterally from the implant (BATA) within 2 rectangular regions of interest (ROIs) 4 mm in height, representing the coronal (parallel-walled) and apical (tapered) aspect of the implant (ROI 1 and ROI 2, respectively) in non-submerged implants. In general, marginal peri-implant bone levels were at or slightly apical to the implant platform, and large amounts of bone-to-implant contact were observed. In contrast, immediately loaded implants placed with the drill-only protocol showed statistically significantly lower BIC values (66% ± 13.7%) compared with those installed with the standard drilling protocol (74.8% ± 11.2%) (P = 0.018). In addition, although marginal bone levels were in most of the immediately loaded implants at or slightly apical to the implant platform, some of the implants installed with the drill-only protocol showed marginal bone loss and crater formation. Thus, in this model system, even slight underpreparation of the implant socket appeared to compromise osseointegration of immediately loaded bone-level tapered implants.
本临床前体内研究的目的是评估改良的“仅钻孔”方案(涉及种植体部位的轻微准备不足)是否可能对新型骨水平锥形种植体的骨整合方面产生影响,而“标准钻孔”方案涉及种植体窝的边缘方面的胶布和轮廓。11头小型猪无牙且完全愈合的下颌骨两侧各2个锥形种植体(8mm长× 4.1 mm Ø, BLT;Institut Straumann AG, Basel, Switzerland)安装了纯钻井或标准钻井方案。标准钻孔方案组的平均插入扭矩值(52±29 Ncm)显著低于单纯钻孔组(70±27 Ncm) (t检验,P≤0.05);通过共振频率分析,两组在种植体稳定性方面无显著差异(分别为75±8比75±6)。一半的种植体立即加载,其余的浸泡,分别提供8周或4周的观察时间。种植体与周围组织的非脱钙组织学和组织形态学分析显示,从种植体平台到第一个冠状骨与种植体接触(f-BIC)的距离、总骨与种植体接触(BIC)占种植体总周长的百分比,两种钻孔方案之间没有显著差异。以及2个4毫米高的矩形感兴趣区域(ROI)内从种植体向外侧延伸1mm的区域(BATA)内的骨密度,代表非浸没种植体的冠状面(平行壁)和根尖面(锥形)(分别为ROI 1和ROI 2)。一般来说,种植体周围的边缘骨水平位于种植体平台的顶端或略微顶端,并且观察到大量的骨与种植体接触。相比之下,采用钻孔方案立即加载的种植体的BIC值(66%±13.7%)明显低于采用标准钻孔方案安装的种植体(74.8%±11.2%)(P = 0.018)。此外,尽管大多数即刻加载的种植体的边缘骨水平位于种植体平台的顶端或略微顶端,但一些采用纯钻孔方案安装的种植体出现了边缘骨丢失和凹坑形成。因此,在该模型系统中,即使种植体窝准备不足,也会损害立即加载的骨水平锥形种植体的骨整合。
{"title":"Effect of Osteotomy Preparation on Osseointegration of Immediately Loaded, Tapered Dental Implants","authors":"Andreas Stavropoulos, David L. Cochran, M. Obrecht, B. Pippenger, Michel Dard","doi":"10.1177/0022034515624446","DOIUrl":"https://doi.org/10.1177/0022034515624446","url":null,"abstract":"The aim of the present preclinical in vivo study was to evaluate whether a modified “drill-only” protocol, involving slight underpreparation of the implant site, may have an effect on aspects of osseointegration of a novel bone-level tapered implant, compared with the “standard drilling” protocol involving taping and profiling of the marginal aspect of the implant socket. In each side of the edentulated and completely healed mandible of 11 minipigs, 2 tapered implants (8 mm long × 4.1 mm Ø, BLT; Institut Straumann AG, Basel, Switzerland) were installed either with the drill-only or the standard drilling protocol. Significantly lower average insertion torque values were recorded for the standard drilling protocol group (52 ± 29 Ncm) compared with the drill-only group (70 ± 27 Ncm) (t test, P ≤ 0.05); no significant difference was observed between the 2 groups regarding implant stability, by means of resonance frequency analysis (75 ± 8 vs. 75 ± 6, respectively). Half of the implants were immediately loaded and the rest were submerged, providing observation times of 8 or 4 wk, respectively. Non-decalcified histological and histomorphometric analysis of the implants with surrounding tissues showed no significant differences between the 2 drilling protocols regarding the distance from the implant platform to the first coronal bone-to-implant contact (f-BIC), the total bone-to-implant contact (BIC) as a percentage of the total implant perimeter, and the bone density in an area extending 1 mm laterally from the implant (BATA) within 2 rectangular regions of interest (ROIs) 4 mm in height, representing the coronal (parallel-walled) and apical (tapered) aspect of the implant (ROI 1 and ROI 2, respectively) in non-submerged implants. In general, marginal peri-implant bone levels were at or slightly apical to the implant platform, and large amounts of bone-to-implant contact were observed. In contrast, immediately loaded implants placed with the drill-only protocol showed statistically significantly lower BIC values (66% ± 13.7%) compared with those installed with the standard drilling protocol (74.8% ± 11.2%) (P = 0.018). In addition, although marginal bone levels were in most of the immediately loaded implants at or slightly apical to the implant platform, some of the implants installed with the drill-only protocol showed marginal bone loss and crater formation. Thus, in this model system, even slight underpreparation of the implant socket appeared to compromise osseointegration of immediately loaded bone-level tapered implants.","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"34 - 41"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515624446","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Tapered Implants in Dentistry 牙科中的锥形种植体
Q1 Medicine Pub Date : 2016-02-29 DOI: 10.1177/0022034516628868
T. G. Wilson, R. J. Miller, R. Trushkowsky, Michel Dard
The most common approach to lessen treatment times is by decreasing the healing period during which osseointegration is established. Implant design parameters such as implant surface, primary stability, thread configuration, body shape, and the type of bone have to be considered to obtain this objective. The relationship that exists between these components will define the initial stability of the implant. It is believed implant sites using a tapered design and surface modification can increase the primary stability in low-density bone. Furthermore, recent experimental preclinical work has shown the possibility of attaining primary stability of immediately loaded, tapered dental implants without compromising healing and rapid bone formation while minimizing the implant stability loss at compression sites. This may be of singular importance with immediate/early functional loading of single implants placed in poor-quality bone. The selection of an implant that will provide adequate stability in bone of poor quality is important. A tapered-screw implant design will provide adequate stability because it creates pressure on cortical bone in areas of reduced bone quality. Building on the success of traditional tapered implant therapy, newer tapered implant designs should aim to maximize the clinical outcome by implementing new technologies with adapted clinical workflows.
减少治疗时间的最常见方法是缩短骨融合建立的愈合时间。为了实现这一目标,必须考虑种植体设计参数,如种植体表面、初级稳定性、螺纹配置、体形和骨类型。这些成分之间存在的关系将决定植入物的初始稳定性。人们认为采用锥形设计和表面修饰的种植体可以增加低密度骨的初级稳定性。此外,最近的临床前实验工作表明,在不影响愈合和快速骨形成的情况下,可以获得立即加载的锥形牙种植体的初级稳定性,同时最大限度地减少种植体在压缩部位的稳定性损失。这对于将单个种植体放置在质量较差的骨内的即时/早期功能负荷来说可能是非常重要的。在质量差的骨中选择能够提供足够稳定性的植入物是很重要的。锥形螺钉种植体设计将提供足够的稳定性,因为它在骨质量降低的区域对皮质骨产生压力。在传统锥形种植体治疗成功的基础上,新的锥形种植体设计应该旨在通过实施适应临床工作流程的新技术来最大化临床结果。
{"title":"Tapered Implants in Dentistry","authors":"T. G. Wilson, R. J. Miller, R. Trushkowsky, Michel Dard","doi":"10.1177/0022034516628868","DOIUrl":"https://doi.org/10.1177/0022034516628868","url":null,"abstract":"The most common approach to lessen treatment times is by decreasing the healing period during which osseointegration is established. Implant design parameters such as implant surface, primary stability, thread configuration, body shape, and the type of bone have to be considered to obtain this objective. The relationship that exists between these components will define the initial stability of the implant. It is believed implant sites using a tapered design and surface modification can increase the primary stability in low-density bone. Furthermore, recent experimental preclinical work has shown the possibility of attaining primary stability of immediately loaded, tapered dental implants without compromising healing and rapid bone formation while minimizing the implant stability loss at compression sites. This may be of singular importance with immediate/early functional loading of single implants placed in poor-quality bone. The selection of an implant that will provide adequate stability in bone of poor quality is important. A tapered-screw implant design will provide adequate stability because it creates pressure on cortical bone in areas of reduced bone quality. Building on the success of traditional tapered implant therapy, newer tapered implant designs should aim to maximize the clinical outcome by implementing new technologies with adapted clinical workflows.","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"28 1","pages":"4 - 9"},"PeriodicalIF":0.0,"publicationDate":"2016-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034516628868","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64931472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Reducing Inequalities in Oral Health in the Africa and Middle East Region. 减少非洲和中东区域口腔健康方面的不平等现象。
Q1 Medicine Pub Date : 2015-07-01 DOI: 10.1177/0022034515575540
A Sheiham, D M Williams

Dentistry is facing many serious challenges and threats. Addressing them will require major changes in strategy. This work outlines the extent of dental disease in the Africa and Middle East Region (AMER) and suggests strategies to reduce inequalities in oral health. The main oral health challenges in the AMER relate to controlling the relentless increase in caries with age. A very conservative estimate of population caries levels suggests that a 5-fold increase in dental personnel would be required just to treat current levels of caries. Hence, we argue that current approaches to control caries in the AMER are both ineffective and unaffordable, and a new model to promote oral health is needed. Unless determinants of noncommunicable diseases are addressed and access to evidence-based minimal intervention dental care is improved, the burden of dental disease will persist. The new oral health promotion model calls for an integrated intersectoral common risk factor approach, namely, "oral health in all policies" (OHiAP). An OHiAP framework will initiate high-level policy initiatives and intersectoral partnerships. Oral health professionals have an important advocacy role in securing the fundamental changes in health strategy needed to control the growing, unjust, and unaffordable burden of oral disease.

牙科面临着许多严峻的挑战和威胁。解决这些问题需要在战略上做出重大改变。这项工作概述了非洲和中东地区(AMER)的牙病程度,并提出了减少口腔健康不平等的战略建议。在美国,主要的口腔健康挑战与控制随着年龄增长而不断增加的龋齿有关。对人口龋齿水平的一个非常保守的估计表明,仅仅治疗目前的龋齿水平就需要牙科人员增加5倍。因此,我们认为目前在美洲控制龋齿的方法既无效又负担不起,需要一种新的模式来促进口腔健康。除非解决非传染性疾病的决定因素,并改善以证据为基础的最低干预牙科保健的可及性,否则牙科疾病的负担将持续存在。新的口腔健康促进模式要求采取综合的跨部门共同风险因素办法,即“所有政策中的口腔健康”(OHiAP)。OHiAP框架将启动高级别政策倡议和部门间伙伴关系。口腔卫生专业人员在确保卫生战略发生根本性变化以控制日益增长的、不公正的和负担不起的口腔疾病负担方面发挥着重要的倡导作用。
{"title":"Reducing Inequalities in Oral Health in the Africa and Middle East Region.","authors":"A Sheiham,&nbsp;D M Williams","doi":"10.1177/0022034515575540","DOIUrl":"https://doi.org/10.1177/0022034515575540","url":null,"abstract":"<p><p>Dentistry is facing many serious challenges and threats. Addressing them will require major changes in strategy. This work outlines the extent of dental disease in the Africa and Middle East Region (AMER) and suggests strategies to reduce inequalities in oral health. The main oral health challenges in the AMER relate to controlling the relentless increase in caries with age. A very conservative estimate of population caries levels suggests that a 5-fold increase in dental personnel would be required just to treat current levels of caries. Hence, we argue that current approaches to control caries in the AMER are both ineffective and unaffordable, and a new model to promote oral health is needed. Unless determinants of noncommunicable diseases are addressed and access to evidence-based minimal intervention dental care is improved, the burden of dental disease will persist. The new oral health promotion model calls for an integrated intersectoral common risk factor approach, namely, \"oral health in all policies\" (OHiAP). An OHiAP framework will initiate high-level policy initiatives and intersectoral partnerships. Oral health professionals have an important advocacy role in securing the fundamental changes in health strategy needed to control the growing, unjust, and unaffordable burden of oral disease. </p>","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"27 1","pages":"4-9"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515575540","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33286946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Prevalence and Severity of Oral Diseases in the Africa and Middle East Region. 非洲和中东地区口腔疾病的流行和严重程度。
Q1 Medicine Pub Date : 2015-07-01 DOI: 10.1177/0022034515582062
A Abid, F Maatouk, L Berrezouga, C Azodo, O Uti, H El-Shamy, A Oginni

This review aims to determine the prevalence and severity of oral health diseases in the Africa and Middle East region (AMER). The profile of oral diseases is not homogeneous across the AMER. There are large disparities between groups. Reliable data are scarce. The prevalence and severity of oral diseases appear to be increasing in the African region, as does associated morbidity. There are substantial differences in inequalities in oral health. Dental caries prevalence is less severe in most African countries than in developed countries, but the high rate of untreated caries reflects the limited resources available and difficulties of access and affordability to essential oral health care services. The prevalence of gingival inflammation is very high in all age groups in several African countries. The prevalence of maxillofacial trauma has increased in many countries, with a wide variation of the incidence and high prevalence of traumatic dental injuries in primary and permanent teeth. Orofacial clefts are among the most common birth defects. Annual incidence of oral cancer is estimated as 25 cases per 100,000 people in Africa. Noma is a major public health problem for the Middle East and North African (MENA) region. Data about human immunodeficiency virus/AIDS are limited, particularly in the MENA region. According to the World Health Organization Regional Committee for Africa report, some fundamental key basic knowledge gaps need to be underlined. They include inequalities in oral health, low priority for oral health, lack of adequate funding, inadequate dental student training, obstacles to medical and dental research, and poor databases. There are very few effective public prevention and oral health promotion programs in the AMER. Universal health coverage is not achievable without scientific research on the effectiveness of health promotion interventions.

本综述旨在确定非洲和中东地区(AMER)口腔健康疾病的患病率和严重程度。口腔疾病的概况在整个美国并不均匀。群体之间存在着巨大的差异。可靠的数据很少。在非洲区域,口腔疾病的流行和严重程度似乎在增加,相关的发病率也在增加。在口腔健康方面的不平等有很大差异。与发达国家相比,大多数非洲国家的龋齿发病率较低,但未经治疗的龋齿率高反映了现有资源有限,以及难以获得和负担得起基本口腔保健服务。在一些非洲国家,牙龈炎症的患病率在所有年龄组中都非常高。颌面部创伤的发病率在许多国家都有所增加,其发病率变化很大,在乳牙和恒牙中创伤性牙损伤的发病率很高。唇腭裂是最常见的先天缺陷之一。据估计,非洲口腔癌的年发病率为每10万人25例。坏疽性口炎是中东和北非地区的一个主要公共卫生问题。关于人体免疫机能丧失病毒/艾滋病的数据有限,特别是在中东和北非区域。根据世界卫生组织非洲区域委员会的报告,需要强调一些关键的基本知识差距。这些问题包括口腔健康方面的不平等、对口腔健康的重视程度较低、缺乏足够的资金、牙科学生培训不足、医学和牙科研究存在障碍以及数据库不足。美国很少有有效的公共预防和口腔健康促进计划。没有对健康促进干预措施的有效性进行科学研究,就无法实现全民健康覆盖。
{"title":"Prevalence and Severity of Oral Diseases in the Africa and Middle East Region.","authors":"A Abid,&nbsp;F Maatouk,&nbsp;L Berrezouga,&nbsp;C Azodo,&nbsp;O Uti,&nbsp;H El-Shamy,&nbsp;A Oginni","doi":"10.1177/0022034515582062","DOIUrl":"https://doi.org/10.1177/0022034515582062","url":null,"abstract":"<p><p>This review aims to determine the prevalence and severity of oral health diseases in the Africa and Middle East region (AMER). The profile of oral diseases is not homogeneous across the AMER. There are large disparities between groups. Reliable data are scarce. The prevalence and severity of oral diseases appear to be increasing in the African region, as does associated morbidity. There are substantial differences in inequalities in oral health. Dental caries prevalence is less severe in most African countries than in developed countries, but the high rate of untreated caries reflects the limited resources available and difficulties of access and affordability to essential oral health care services. The prevalence of gingival inflammation is very high in all age groups in several African countries. The prevalence of maxillofacial trauma has increased in many countries, with a wide variation of the incidence and high prevalence of traumatic dental injuries in primary and permanent teeth. Orofacial clefts are among the most common birth defects. Annual incidence of oral cancer is estimated as 25 cases per 100,000 people in Africa. Noma is a major public health problem for the Middle East and North African (MENA) region. Data about human immunodeficiency virus/AIDS are limited, particularly in the MENA region. According to the World Health Organization Regional Committee for Africa report, some fundamental key basic knowledge gaps need to be underlined. They include inequalities in oral health, low priority for oral health, lack of adequate funding, inadequate dental student training, obstacles to medical and dental research, and poor databases. There are very few effective public prevention and oral health promotion programs in the AMER. Universal health coverage is not achievable without scientific research on the effectiveness of health promotion interventions. </p>","PeriodicalId":7300,"journal":{"name":"Advances in Dental Research","volume":"27 1","pages":"10-7"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0022034515582062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33286947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 55
期刊
Advances in Dental Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1