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Percentage of Weight Placed on Acute, Subacute, and Chronic Foot and Ankle Injuries in Weightbearing Radiographs. 负重x线片中急性、亚急性和慢性足踝关节损伤的重量百分比。
IF 2.1 Pub Date : 2026-02-10 DOI: 10.1177/19386400251411742
Natalie R Black, Jessica D Martella, Megna Panchbhavi, Jie Chen, Vinod K Panchbhavi

BackgroundWeightbearing radiography is an essential diagnostic tool in orthopedics, especially in the setting of foot and ankle pathology. However, there is a lack of studies examining the percentage of weight placed on a limb during weightbearing x-rays, potentially affecting the quality of the radiograph.MethodsOver a 3-month period, the percentage of weight placed through an injured extremity was recorded for 434 patients receiving weightbearing radiographs of the foot or ankle in a single clinic.ResultsFor the overwhelming majority of radiographs, patients placed less than half their weight on their injured extremity. Lateral radiographs had a lesser percentage of weightbearing compared with anteroposterior (P = .0096) and oblique (P = .0042) radiographs. Patients with acute injuries placed less weight on their extremity in lateral foot radiographs compared with those with acute injuries (P = .0023). A high variability of weight was placed through the extremity regardless of pathology.ConclusionThese results highlight the need for clinician awareness regarding the discrepancies in weightbearing radiography, the importance of technician and patient education on technique and importance of quality imaging, and the plethora of questions that still remain regarding what characteristics comprise a sufficient weightbearing radiograph.Levels of Evidence:Level III: Prognostic.

背景:负重x线摄影在骨科中是一种重要的诊断工具,尤其是在足部和踝关节病理方面。然而,在进行负重x光检查时,缺乏检查肢体重量百分比的研究,这可能会影响x光片的质量。方法在3个月的时间里,对在同一诊所接受足部或踝关节负重x线片检查的434例患者进行记录。结果对于绝大多数x线片,患者在受伤的肢体上放置的重量不到体重的一半。与正位片(P = 0.0096)和斜位片(P = 0.0042)相比,侧位片的负重百分比较小。与急性损伤患者相比,急性损伤患者在侧足x线片上对四肢的负重更轻(P = 0.0023)。无论病理如何,通过四肢放置高度可变性的体重。结论这些结果突出了临床医生对负重片差异的认识,技术人员和患者在技术和质量成像方面的教育的重要性,以及关于什么特征构成足够的负重片的大量问题仍然存在。证据等级:III级:预后。
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引用次数: 0
Influence of Implant Design on Clinical Outcomes, Complications, and Revisions Rate in Anterior Approach Total Ankle Arthroplasty A Systematic Review and Meta-Analysis. 前路全踝关节置换术中植入物设计对临床结果、并发症和修复率的影响:系统回顾和荟萃分析。
IF 2.1 Pub Date : 2026-02-10 DOI: 10.1177/19386400251414323
Giammarco Gardini, Silvio Caravelli, Edoardo Cassanelli, Tosca Cerasoli, Pietro Cimatti, Nicolandrea Del Piccolo, Giulio Maria Marcheggiani Muccioli, Massimiliano Mosca

BackgroundTotal ankle arthroplasty (TAA) is increasingly used as an alternative to arthrodesis for end-stage ankle arthritis. The extent to which implant bearing type and design evolution influence outcomes and survival remains debated.MethodsA systematic review and meta-analysis was conducted in accordance with PRISMA guidelines and registered on PROSPERO (CRD420251073944). PubMed, Embase, and Scopus were searched for English-language studies (2004-2025) reporting anterior-approach TAA with specified implant generation (I-IV) and bearing type (fixed [FB] vs mobile [MB]). Studies with a QualSyst score ≥ 75% were included. Primary outcomes were American Orthopaedic Foot & Ankle Society (AOFAS) score, visual analogue scale (VAS), range of motion (ROM), complications, and revisions.ResultsForty-two studies comprising 4,271 implants were analyzed (FB: 1,546; MB: 2,725). Functional improvements were mainly driven by implant generation rather than bearing type. ΔAOFAS increased from 33.7 ± 22.3 in Gen II to 44.5 ± 28.3 in Gen IV (P < .001). ΔVAS varied across generations (Gen II 5.8 ± 2.1; Gen III 4.6 ± 2.8; Gen IV 5.46 ± 1.60; all P < .001 vs baseline). MB implants showed lower pre- and postoperative AOFAS scores but comparable ΔAOFAS to FB designs (36.4 vs 37.5; P = .358). MB systems provided greater pain relief (ΔVAS 5.62 vs 4.60; P < .001) but had higher revision rates (12.0% vs 6.2%; P < .001). FB implants achieved superior postoperative ROM gains in plantarflexion (+6.0° vs -2.9°; P < .001) and dorsiflexion (+2.71° vs +0.75°; P < .001). Excluding Gen I, complication rates decreased from 32.6% in Gen II to 18.8% in Gen III and 10.3% in Gen IV (all P < .01); revision rates declined from 16.5% (Gen II) and 9.6% (Gen III) to 0.5% (Gen IV) (P < .01).ConclusionsImplant generation is the primary determinant of outcomes, complications, and survival in anterior-approach TAA. Bearing type played a secondary role: MB devices provided greater pain relief, whereas FB systems achieved superior ROM recovery and lower revision risk. Fourth-generation implants yielded the most reliable results. Further prospective studies with standardized functional and kinematic assessments are warranted.Level of Clinical Evidence:Level I-Systematic Review/Meta-Analysis.

背景:全踝关节置换术(TAA)越来越多地被用作终末期踝关节融合术的替代方法。种植体承载类型和设计演变对结果和生存的影响程度仍存在争议。方法按照PRISMA指南进行系统评价和荟萃分析,并在PROSPERO注册(CRD420251073944)。检索PubMed, Embase和Scopus的英语研究(2004-2025),报告前路TAA,指定种植体生成(I-IV)和轴承类型(固定[FB] vs移动[MB])。纳入QualSyst评分≥75%的研究。主要结果是美国骨科足踝协会(AOFAS)评分、视觉模拟量表(VAS)、活动范围(ROM)、并发症和修复。结果共分析了42项研究,包括4271个种植体(FB: 1546; MB: 2725)。功能的改善主要是由种植体代而不是轴承类型驱动的。ΔAOFAS从第2代的33.7±22.3增加到第4代的44.5±28.3 (P < 0.001)。ΔVAS的代际差异(II代5.8±2.1;III代4.6±2.8;IV代5.46±1.60;与基线相比,所有P < 0.001)。MB植入物的术前和术后AOFAS评分较低,但与FB设计相当ΔAOFAS (36.4 vs 37.5; P = .358)。MB系统提供了更大的疼痛缓解(ΔVAS 5.62 vs 4.60; P < 0.001),但有更高的修订率(12.0% vs 6.2%; P < 0.001)。FB植入物在跖屈(+6.0°vs -2.9°,P < 0.001)和背屈(+2.71°vs +0.75°,P < 0.001)方面获得了更好的术后ROM增益。排除第1代,并发症发生率从第2代的32.6%下降到第3代的18.8%和第4代的10.3%(均P < 0.01);修正率从16.5%(第二代)和9.6%(第三代)下降到0.5%(第四代)(P < 0.01)。结论植体的产生是前路TAA预后、并发症和生存的主要决定因素。轴承类型发挥了次要作用:MB设备提供了更大的疼痛缓解,而FB系统实现了更好的ROM恢复和更低的翻修风险。第四代植入物产生了最可靠的结果。进一步的前瞻性研究与标准化的功能和运动评估是必要的。临床证据水平:一级系统评价/荟萃分析。
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引用次数: 0
Early Definitive Fixation of Talus Fractures Is Safe: A Retrospective Review. 距骨骨折的早期确定性固定是安全的:回顾性综述
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2023-12-14 DOI: 10.1177/19386400231218333
Daniel T DeGenova, Klay B Miller, Alex S Paulini, Anthony J Melaragno, Trent Davis, Brett Hoffman, Benjamin C Taylor

BackgroundTalus fractures are often result of high energy mechanisms and can lead to devastating complications. Treatment is often operative; however, the appropriate timing of this has been debated. The purpose of this study is to determine the efficacy and safety of the early treatment of talus fractures.MethodsPatients aged 18 years or older who underwent definitive operative stabilization of their talus fracture at a single urban level 1 trauma center were retrospectively reviewed. Patients were split into 2 groups based on their time to definitive fixation: ≤ or >24 hours. Pertinent demographic, surgical, and follow-up data were collected and analyzed.ResultsA total of 108 fractures were treated with 65 in the ≤24 hours fixation group and 43 in the >24 hours fixation group. Fractures involving the talar neck were the most commonly treated fracture pattern followed by the body and the head. There was no difference between the 2 groups in length to full weight bearing, union, or time to union. Open fracture was found to be the only significant risk factor for nonunion in both groups. There was no significant difference in infection or arthrodesis rates between the 2 groups.ConclusionDefinitive treatment of talus fractures within 24 hours from presentation is both safe and effective with equal outcomes and without increased complications when compared with those injuries that undergo delayed or staged definitive fixation.Level of Evidence:Level III.

背景:距骨骨折通常是高能量机制的结果,可导致破坏性并发症。治疗通常采用手术,但手术的适当时机一直存在争议。本研究旨在确定早期治疗距骨骨折的有效性和安全性:方法:回顾性研究了在一个城市一级创伤中心接受明确手术稳定治疗的 18 岁或以上距骨骨折患者。根据患者的最终固定时间分为两组:≤或>24小时。收集并分析了相关的人口统计学、手术和随访数据:结果:共治疗了108例骨折,其中≤24小时固定组65例,>24小时固定组43例。涉及距骨颈的骨折是最常见的骨折类型,其次是距骨体和距骨头。两组患者在完全负重时间、骨折愈合时间和骨折愈合时间上没有差异。在两组患者中,开放性骨折是导致骨折不愈合的唯一重要风险因素。两组患者的感染率和关节置换率无明显差异:结论:与接受延迟或分期明确固定治疗的伤者相比,在距骨骨折发生后24小时内进行明确治疗既安全又有效,且疗效相同,不会增加并发症:证据等级:三级。
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引用次数: 0
Foot and Ankle Patient Education Materials and Artificial Intelligence Chatbots: A Comparative Analysis. 足踝患者教育材料与人工智能聊天机器人:比较分析。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-03-19 DOI: 10.1177/19386400241235834
Aarav S Parekh, Joseph A S McCahon, Amy Nghe, David I Pedowitz, Joseph N Daniel, Selene G Parekh

BackgroundThe purpose of this study was to perform a comparative analysis of foot and ankle patient education material generated by the AI chatbots, as they compare to the American Orthopaedic Foot and Ankle Society (AOFAS)-recommended patient education website, FootCareMD.org.MethodsChatGPT, Google Bard, and Bing AI were used to generate patient educational materials on 10 of the most common foot and ankle conditions. The content from these AI language model platforms was analyzed and compared with that in FootCareMD.org for accuracy of included information. Accuracy was determined for each of the 10 conditions on a basis of included information regarding background, symptoms, causes, diagnosis, treatments, surgical options, recovery procedures, and risks or preventions.ResultsWhen compared to the reference standard of the AOFAS website FootCareMD.org, the AI language model platforms consistently scored below 60% in accuracy rates in all categories of the articles analyzed. ChatGPT was found to contain an average of 46.2% of key content across all included conditions when compared to FootCareMD.org. Comparatively, Google Bard and Bing AI contained 36.5% and 28.0% of information included on FootCareMD.org, respectively (P < .005).ConclusionPatient education regarding common foot and ankle conditions generated by AI language models provides limited content accuracy across all 3 AI chatbot platforms.Level of Evidence:Level IV.

研究背景本研究的目的是对人工智能聊天机器人生成的足踝患者教育材料进行比较分析,并将其与美国骨科足踝协会(AOFAS)推荐的患者教育网站 FootCareMD.org 进行比较:方法:使用 ChatGPT、Google Bard 和 Bing AI 生成有关 10 种最常见足踝疾病的患者教育材料。对这些人工智能语言模型平台的内容进行了分析,并与 FootCareMD.org 中的内容进行了比较,以确定所含信息的准确性。根据所包含的背景、症状、病因、诊断、治疗、手术选择、恢复过程、风险或预防等方面的信息,分别确定了 10 种病症的准确性:与 AOFAS 网站 FootCareMD.org 的参考标准相比,人工智能语言模型平台在所分析文章的所有类别中的准确率始终低于 60%。与 FootCareMD.org 相比,ChatGPT 在所有包含的条件中平均包含 46.2% 的关键内容。相比之下,Google Bard 和 Bing AI 包含的信息分别为 FootCareMD.org 的 36.5% 和 28.0%(P < .005):人工智能语言模型生成的有关常见足踝疾病的患者教育在所有3个人工智能聊天机器人平台上都提供了有限的内容准确性:证据级别:IV级
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引用次数: 0
Treatment of External Fixator Pin Tract Deep Infections With an Antibiotic "Sparkler". 用抗生素 "火花塞 "治疗外固定器针道深度感染。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-03-07 DOI: 10.1177/19386400241235389
Lee M Hlad, Jacob N Rizkalla, Eric So, John E Herzenberg

Pin tract infections are virtually universal complications with the use of external fixation. While most are superficial and respond to oral antibiotics and local care, septic loosening may occur at the bone-pin interface, which may lead to instability of the fixator, catastrophic failure, fracture, and long-term osteomyelitis. Classification systems and prevention protocols have been developed to address this ubiquitous complication. Treatment of severe pin tract infections often requires debridement, parenteral antibiotics, and removal of the offending pin or the entire external fixator. In cases of osteomyelitic pin tracks, a sizable cavity is often present. We describe a simple technique for treatment of deep bone pin tract infection through the use of debridement, irrigation, and an antibiotic "sparkler," which is a specially prepared percutaneous implant of antibiotic laden bone cement.Levels of Evidence: Level 5.

针道感染几乎是使用外固定器的普遍并发症。虽然大多数感染都是浅表性的,只需口服抗生素和局部护理即可治愈,但骨针接口处可能会发生化脓性松动,从而导致固定器失稳、灾难性故障、骨折和长期骨髓炎。针对这种无处不在的并发症,已经制定了分类系统和预防方案。治疗严重的针道感染通常需要进行清创、肠外抗生素治疗以及移除有问题的针或整个外固定器。在骨髓性钉道感染的病例中,通常会出现较大的空腔。我们介绍了一种通过清创、冲洗和抗生素 "sparkler "治疗深层骨针道感染的简单技术,"sparkler "是一种特殊制备的经皮植入抗生素骨水泥:证据等级:5 级。
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引用次数: 0
Indications, Associated Procedures, and Results of Ankle Plafond-Plasty for Varus Ankle Osteoarthritis: A Systematic Review and Meta-Analysis. 踝关节板成形术治疗曲踝骨关节炎的适应症、相关程序和结果:系统回顾与元分析》。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-03-19 DOI: 10.1177/19386400241236321
Simone Ottavio Zielli, Antonio Mazzotti, Elena Artioli, Daniele Marcolli, Alberto Arceri, Simone Bonelli, Cesare Faldini

BackgroundsPlafond-plasty is a joint-preserving procedure to treat varus ankle osteoarthritis (OA) with asymmetrical joint involvement. The aim of this systematic review and meta-analysis was to evaluate indications, different surgical techniques, associated procedures, and results of plafond-plasty in varus ankle OA and to analyze the level of evidence (LOE) and quality of evidence (QOE) of the included studies.MethodsA systematic review of the literature was performed using MEDLINE, Embase, and Cochrane.ResultsFive studies evaluating 99 ankles were included. A non-rigid varus ankle deformity and an ankle OA Takakura stage 3b or less were the most recommended pre-operative indications. Meta-analysis showed a significant post-operative improvement in clinical and radiological parameters. Many associated surgical procedures have been reported, the most frequent being medial additional supramalleolar osteotomy and lateral ankle ligament reconstruction. The level of evidence and methodological quality assessment of the included studies showed an overall low quality.ConclusionPlafond-plasty seems to be a promising surgical option when managing varus ankle OA with asymmetrical joint involvement, extending the indications for joint sparing surgery. Additional associated procedures should be carefully evaluated case-by-case.Levels of Evidence:IV.

背景:板状成形术是一种保留关节的手术,用于治疗关节受累不对称的曲踝骨关节炎(OA)。本系统综述和荟萃分析旨在评估板状成形术在踝关节OA变曲中的适应症、不同手术技术、相关程序和结果,并分析纳入研究的证据级别(LOE)和证据质量(QOE):方法:使用 MEDLINE、Embase 和 Cochrane 对文献进行系统性回顾:结果:共纳入了 5 项研究,评估了 99 个踝关节。非刚性踝关节屈曲畸形和踝关节 OA 高仓分期 3b 或以下是最推荐的术前适应症。Meta 分析表明,术后临床和放射学参数均有显著改善。许多相关的外科手术都有报道,最常见的是内侧附加踝上截骨术和外侧踝关节韧带重建术。对纳入研究的证据水平和方法质量评估显示,总体质量较低:在治疗不对称关节受累的曲踝OA时,Plafond成形术似乎是一种很有前景的手术选择,它扩大了关节疏通手术的适应症。证据等级:IV:证据等级:IV。
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引用次数: 0
Lapidus Arthrodesis for Correction of Hallux Valgus Deformity: A Systematic Review and Meta-Analysis. 用于矫正拇指外翻畸形的 Lapidus 关节置换术:系统回顾与元分析》。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-03-14 DOI: 10.1177/19386400241233832
Maximilian Waehner, Kajetan Klos, Hans Polzer, Robbie Ray, Thomas Lorchan Lewis, Hazibullah Waizy

Background: The aim of this study was to evaluate and compare different fixation methods to achieve Tarsometatarsal joint I (TMT-1) arthrodesis in patients with hallux valgus regarding radiographic correction, complication profile, and clinical outcomes.

Methods: A systematic review and meta-analysis included primary literature results of evidence level 1 to 3 studies in German and English. Inclusion and exclusion criteria were established and applied, along with parameters suitable for comparison of data.

Results: 16 studies with a total of 1176 participants met the inclusion criteria for this analysis. Twelve evaluation criteria were compared among 3 fixation techniques; comprised of a screw-only, dorsomedial plating- and plantar plating cohort. There was no statistical difference in deformity correction (both intermetatarsal- and hallux valgus angle), or AOFAS score between the cohorts. The complication rate was 13% in the plantar-, 19.5% in the dorsomedial-, and 24.5% in the screw cohort. Nonunion was seen in 0.7% of participants in the plantar, 1.4% in the dorsomedial, and 5.3% in the screw group. The time until complete weightbearing correlated positively with the development of nonunion, with a coefficient of 0.376 (P = .009). Hardware removal was performed in 11.8% of patients in the dorsomedial cohort, 7.7% in the screw cohort, and 3.6% in the plantar cohort.

Conclusion: Based on the results of meta-analysis of heterogeneous studies, plantar plating facilitated early weightbearing and patient mobilization compared to the other fixation methods, while carrying the lowest nonunion, hardware removal, and general complication risk. However, owing to the relatively small number of patients in the plantar plating group, more work is necessary to elucidate the benefits of plantar plating for a first tarsometatarsal joint arthrodesis. Development of complications appears to be largely dependent on the fixation model, rather than patient mobilization alone.Level of Evidence: 3.

研究背景本研究旨在评估和比较不同的固定方法,以实现拇指外翻患者跖跗关节I型(TMT-1)关节固定术的放射学矫正、并发症情况和临床疗效:一项系统性回顾和荟萃分析纳入了德文和英文证据等级 1 至 3 级研究的主要文献结果。方法:系统性回顾和荟萃分析纳入了德文和英文证据等级为 1 至 3 的主要文献研究结果,制定并应用了纳入和排除标准,以及适合数据比较的参数:共有 16 项研究、1176 名参与者符合本次分析的纳入标准。对 3 种固定技术的 12 项评估标准进行了比较,包括纯螺钉固定、背内侧钢板固定和足底钢板固定。两组患者在畸形矫正(跖间角和拇指外翻角)或 AOFAS 评分方面没有统计学差异。并发症发生率为足底13%,背内侧19.5%,螺钉组24.5%。足底、背内侧和螺钉组分别有0.7%、1.4%和5.3%的参与者出现骨不连。完全负重前的时间与发生骨不连呈正相关,系数为 0.376 (P = .009)。背侧队列中有11.8%的患者、螺钉队列中有7.7%的患者、足底队列中有3.6%的患者进行了硬件移除:结论:根据不同研究的荟萃分析结果,与其他固定方法相比,足底钢板固定有利于患者早期负重和活动,同时非愈合、硬件移除和一般并发症风险最低。然而,由于足底固定组的患者人数相对较少,因此有必要开展更多的工作来阐明足底固定对第一跖跗关节关节置换术的益处。并发症的发生似乎在很大程度上取决于固定模式,而不仅仅是患者的活动能力:3.
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引用次数: 0
Charcot Neuroarthropathy Is Associated With Higher Rates of Phantom Limb After Lower Extremity Amputation. 夏科神经关节病与较高的下肢截肢后幻肢率有关。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-02-12 DOI: 10.1177/19386400241230597
Hannah H Nam, Brandon J Martinazzi, F Jeffrey Lorenz, Gregory J Kirchner, Vincenzo Bonaddio, Adeshina Adeyemo, Kempland C Walley, Michael C Aynardi

BackgroundThe incidence of phantom limb pain in patients with Charcot neuroarthropathy who undergo major amputation is not well described. The purpose of this study was to determine whether patients with Charcot neuroarthropathy and diabetes who underwent either a below-knee amputation (BKA) or above-knee amputation (AKA) had an increased rate of phantom limb pain compared with those with a diagnosis of diabetes alone.MethodsUsing international classification of disease (ICD) and common procedural terminology (CPT) codes, the TriNetX research database identified 10 239 patients who underwent BKA and 6122 who underwent AKA between 2012 and 2022. Diabetic patients with and without Charcot neuroarthropathy were compared in terms of demographics and relative risk of developing phantom limb pain after AKA or BKA.ResultsAge, sex, ethnicity, and race did not significantly differ between groups. Charcot neuroarthropathy was associated with significantly increased risk of phantom limb pain following both BKA (risk ratio [RR]: 1.2, 95% confidence interval [CI]: 1.1-1.3, P < .01) and AKA (RR: 1.6, 95% CI: 1.2-2.3, P < .0068).ConclusionOur results indicate that patients with a coexisting diagnosis of Charcot neuroarthropathy who require BKA or AKA may have an increased risk of developing phantom limb pain.Levels of Evidence: Level III.

背景:对于接受大截肢手术的夏科神经性关节病患者幻肢痛的发生率,目前还没有很好的描述。本研究旨在确定接受膝下截肢(BKA)或膝上截肢(AKA)的Charcot神经性关节病合并糖尿病患者的幻肢痛发生率是否高于仅诊断为糖尿病的患者:TriNetX研究数据库使用国际疾病分类(ICD)和通用程序术语(CPT)代码,确定了2012年至2022年期间接受BKA手术的10 239名患者和接受AKA手术的6122名患者。研究人员比较了患有和未患有夏科神经关节病的糖尿病患者的人口统计学特征以及接受 AKA 或 BKA 后出现幻肢痛的相对风险:两组患者的年龄、性别、民族和种族无明显差异。夏科神经关节病与 BKA(风险比 [RR]:1.2,95% 置信区间 [CI]:1.1-1.3,P < .01)和 AKA(RR:1.6,95% 置信区间 [CI]:1.2-2.3,P < .0068)后发生幻肢痛的风险显著增加有关:结论:我们的研究结果表明,合并诊断为Charcot神经性关节病并需要BKA或AKA的患者发生幻肢痛的风险可能会增加:III级。
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引用次数: 0
Advancements in Managing Wound Biofilm: A Systematic Review and Meta-analysis of Randomized Controlled Trials on Topical Modalities. 处理伤口生物膜的进展:关于局部疗法的随机对照试验的系统回顾和元分析》。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-01-28 DOI: 10.1177/19386400231225708
Adam Astrada, Rian Adi Pamungkas, Khoirul Rista Abidin

Despite numerous available agents claiming anti-biofilm properties on wounds, the substantiating evidence remains inconclusive. This study aimed to assess the immediate impact of topical wound treatments on wound biofilm and healing outcomes in acute and chronic ulcers. We comprehensively searched PubMed, ClinicalTrials.gov, and Google Scholar. In addition, eligible gray literature was incorporated. English-language randomized controlled trials (RCTs), observational, cohort, and case-control studies targeting biofilm prevention, inhibition, or elimination across diverse wound types were included. Primary outcomes included biofilm presence and elimination, supplemented by secondary outcomes encompassing reduced wound size, complete closure, and diminished infection indicators. Bacterial load reduction and biofilm presence were also assessed. Twenty-eight articles met the inclusion criteria. Various modalities were identified, including biofilm-visualization techniques, such as wound blotting and handheld autofluorescence imaging. Pooled analysis for the primary outcomes was infeasible due to limited eligible studies and data-reporting challenges. As for the secondary outcomes, the pooled analysis for complete surgical wound closure (2 RCTs, yielding n=284) and presence of surgical site infections/inflammation (2 RCTs, yielding n=284) showed no significant difference, with a log odds ratio (LOD) of 0.58 (95% confidence interval [CI]: -.33, 1.50) and LOD -0.95 (95% CI: -3.54, 1.64; τ2 = 2.32, Q = 2.71, P = .10), respectively. Our findings suggest insufficient evidence to support anti-biofilm claims of topical modalities. Clinicians' skill appears to play a pivotal role in biofilm elimination and wound healing enhancement, with potential optimization through visual-guided techniques, such as wound blotting and autofluorescence imaging. More rigorous clinical trials are warranted to ascertain the efficacy of these techniques.Level of Evidence: Therapeutic, 1A.

尽管市面上有许多药剂声称具有抗伤口生物膜的特性,但相关证据仍不确定。本研究旨在评估局部伤口治疗对伤口生物膜和急慢性溃疡愈合效果的直接影响。我们全面检索了 PubMed、ClinicalTrials.gov 和 Google Scholar。此外,我们还纳入了符合条件的灰色文献。我们纳入了针对不同类型伤口的生物膜预防、抑制或消除的英文随机对照试验 (RCT)、观察性研究、队列研究和病例对照研究。主要结果包括生物膜的存在和消除,次要结果包括伤口缩小、完全闭合和感染指标降低。此外,还对细菌量减少和生物膜存在情况进行了评估。有 28 篇文章符合纳入标准。确定了各种模式,包括生物膜可视化技术,如伤口印迹和手持式自动荧光成像。由于符合条件的研究有限以及数据报告方面的挑战,对主要结果进行汇总分析是不可行的。至于次要结果,对手术伤口完全闭合(2 项研究,样本数=284)和出现手术部位感染/炎症(2 项研究,样本数=284)的汇总分析显示没有显著差异,对数几率比 (LOD) 分别为 0.58(95% 置信区间 [CI]:-.33,1.50)和 LOD -0.95(95% CI:-3.54,1.64;τ2 = 2.32,Q = 2.71,P = .10)。我们的研究结果表明,没有足够的证据支持外用疗法抗生物膜的说法。临床医生的技术似乎在消除生物膜和促进伤口愈合方面起着关键作用,通过视觉引导技术(如伤口印迹和自动荧光成像)可对其进行优化。要确定这些技术的疗效,需要进行更严格的临床试验:治疗,1A。
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引用次数: 0
Parallax and Distortion in Fluoroscopy Units. 透视装置中的视差和失真。
IF 2.1 Pub Date : 2026-02-01 Epub Date: 2024-01-28 DOI: 10.1177/19386400231226028
Joseph R Brown, Zachary P Hill, Ross Groeschl, Robert W Mendicino, Brian Steginsky, Joshua Houser

BackgroundParallax is an imaging phenomenon where an object appears to be at different positions when viewed from different angles. Distortion can occur secondary to internal fluoroscopic, or external environmental, factors. Fluoroscopy is a vital tool to assist surgeons intraoperatively. However, parallax and distortion can lead to inaccuracy, potentially leading to incorrect surgical decisions. The purpose of this study was to investigate the prevalence of parallax/distortion in large fluoroscopy units at a level-1 trauma center.MethodsTwo types of C-arm models were evaluated, including (1) round image intensifiers, and (2) flat plate detectors (FPD). A square plexiglass grid with embedded wire at ½-in intervals was created, with a round metal washer secured centrally. The grid was placed 16 in from the image intensifier. A metal ball bearing (BB) was secured to the center of the x-ray tube. Fluoroscopic images were obtained until the BB and washer were "center-center." A straight blade served as a fiducial marker to ensure there was no off-axis angulation. Standard anterior-posterior and lateral views were obtained. External factors were considered, tested, and limited. Images were printed and the patterns of parallax/distortion were identified.ResultsAll 11/11 (100%) of fluoroscopy units had some degree of parallax and/or distortion. We noted 3 different patterns, including sigmoidal, converging, and diverging. The FPD units had less apparent distortion overall; however, two-thirds (66%) were off-axis in the x- and y-axes in relation to the fiducial marker.ConclusionAll fluoroscopy units had varying degrees and patterns of parallax/distortion. We noted less overall distortion in FPDs. However, some of these units may produce images that are off-axis. This research has important implications for improving the accuracy of intraoperative fluoroscopy. Musculoskeletal surgeons should understand the limitations of fluoroscopy and how to combat parallax distortion to improve surgical outcomes and reduce patient morbidity.Level of Evidence:Level V.

背景:视差是一种成像现象,即从不同角度观察时,物体看起来处于不同的位置。透视内部或外部环境因素都可能导致失真。透视是协助外科医生术中操作的重要工具。然而,视差和失真会导致误差,从而可能导致错误的手术决策。本研究旨在调查一级创伤中心大型透视设备中视差/失真的普遍程度:评估了两种型号的 C 臂,包括 (1) 圆形图像增强器和 (2) 平板探测器 (FPD)。我们制作了一个正方形有机玻璃网格,每隔 1/2英寸嵌入一根金属丝,中间固定一个圆形金属垫圈。网格距离图像增强器 16 英寸。金属球轴承 (BB) 固定在 X 射线管中心。拍摄透视图像,直到 BB 和垫圈 "居中"。直刀片作为靶标,确保没有偏离轴线的角度。获得标准的前后视图和侧视图。对外部因素进行了考虑、测试和限制。打印图像并确定视差/失真的模式:所有 11/11 台透视设备(100%)都存在一定程度的视差和/或扭曲。我们注意到 3 种不同的模式,包括乙型、收敛型和发散型。FPD透视设备总体上变形较少,但三分之二(66%)的X轴和Y轴与靶标偏离轴线:结论:所有透视设备都存在不同程度和模式的视差/失真。我们注意到FPD的总体失真较少。然而,其中一些设备可能会产生偏离轴线的图像。这项研究对提高术中透视的准确性具有重要意义。肌肉骨骼外科医生应了解透视的局限性以及如何消除视差失真,以提高手术效果并降低患者发病率:证据等级:V 级。
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引用次数: 0
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Foot & ankle specialist
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