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Exploring behavioral dynamics: an in-depth analysis of adult students with disabilities. 探索行为动力学:对成年残疾学生的深入分析。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1653140
Ravi P Pandey, Shahma Shirin, Tanya Sharma, Vivek Singh, Komal Bumra, Manshi Tanwar, Vidushi Dixit, Shantesh Kumar Singh, Indu Bala, Pradip Kumar Gupta, Mithilesh Kumar Tiwari, Purnima Awasthi, Manisha Rani, Kriti Singh, Vikash Kumar

Background and aim: This qualitative study delves into the behavioral nuances of disabled students concerning their interactions with siblings and schoolmates. The main objective of this study was to explore the behavioral dynamics of disabled students through the perspective of their siblings, parents and teachers by using systematic thematic analysis approach.

Method: The data was collected from Vilak Foundation in Malappuram, Kerala by conducting semi-structured interviews with five teachers and parents of 20 persons with disabilities affected by various disabilities like autism spectrum disorder, cerebral palsy, abnormal brain growth and down syndrome.

Results: Thematic analysis process was used to generate thematic map in three stages- initial, developed and final thematic. The six-step process of this technique helped in systematic extraction of 47 codes and formation of 09 broad themes. These are introversion, communication factor, aggression, attachment behavior, emotional awareness, morality, empathy, envy and inappropriate sexual behaviour.

Discussion: Extracted and translated verbatim have been described in-detail by the researcher in the discussion section of the study. The importance of attachment, avoidance, and emotional intelligence must be taken into account when developing strategies to support the emotional health and social competence of disabled adult students.

背景与目的:本研究旨在探讨残障学生与兄弟姐妹及同学互动的行为差异。本研究的主要目的是运用系统的主题分析法,从残障学生的兄弟姐妹、父母和老师的角度探讨残障学生的行为动态。方法:数据来自喀拉拉邦马拉普拉姆的Vilak基金会,对20名自闭症谱系障碍、脑瘫、脑发育异常和唐氏综合症等各类残疾儿童的5名教师和家长进行半结构化访谈。结果:采用专题分析流程,分专题初始、专题发展和专题最终三个阶段生成专题图。该技术的六步过程有助于系统地提取47个代码和09个广泛主题的形成。这些因素包括内向、沟通因素、攻击性、依恋行为、情感意识、道德、同理心、嫉妒和不适当的性行为。讨论:研究者在研究的讨论部分逐字摘录和翻译了详细的描述。在制定支持残疾成人学生情绪健康和社会能力的策略时,必须考虑到依恋、回避和情商的重要性。
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引用次数: 0
Case Report: Focused shockwave therapy (fESWT) in thumb carpometacarpal joint osteoarthritis: a single case study. 病例报告:聚焦冲击波疗法(fESWT)治疗拇指腕掌关节骨性关节炎:单个病例研究。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1716305
Timmy Gustafsson, Sofia Ryman Augustsson

Background: Several studies have demonstrated the efficacy of shock wave therapy in managing OA-related pain and improving joint function but evidence specific to thumb CMC joint OA remains limited. Therefore, the aim of this study was to evaluate the effectiveness of fESWT in reducing pain and improving function as well as to assess the safety and tolerability of this intervention, providing insight into its potential role as a non-invasive and long-term alternative for patients unresponsive to conventional therapies or seeking to avoid surgery.

Methods: A 64-year-old woman with radiographically confirmed bilateral CMC OA and persistent symptoms unresponsive to prior conservative treatments received three weekly fESWT sessions. Energy flux density was individually adjusted per session based on tolerance. Outcome measures included the QuickDASH questionnaire and grip strength testing, assessed at baseline, 2-, 8-, 26-, and 52-weeks post-intervention.

Results: Treatment was well tolerated with no adverse events. QuickDASH scores improved from 20.5 at baseline to 2.3 at 52 weeks, indicating an improvement in pain and functional disability. Grip strength increased by 29.5% in the right hand and 17.4% in the left hand over the same period. Subjectively, the patient reported pain relief, functional improvement, and sustained benefit at one-year follow-up.

Conclusions: This case demonstrates the potential of individualized fESWT as a safe and effective intervention for thumb CMC OA, with improvements in pain and function lasting up to 12 months. These findings support further investigation of fESWT in larger controlled studies and highlight the importance of individualized dosing strategies in clinical practice.

背景:一些研究已经证明冲击波治疗在治疗关节炎相关疼痛和改善关节功能方面的有效性,但针对拇指CMC关节关节炎的证据仍然有限。因此,本研究的目的是评估fESWT在减轻疼痛和改善功能方面的有效性,以及评估该干预措施的安全性和耐受性,从而深入了解其作为对常规治疗无反应或寻求避免手术的患者的非侵入性和长期替代方案的潜在作用。方法:一名64岁女性,影像学证实双侧CMC OA,持续症状对既往保守治疗无反应,每周接受3次fESWT治疗。能量通量密度根据容忍度在每次治疗中单独调整。结果测量包括QuickDASH问卷和握力测试,分别在干预后的基线、2周、8周、26周和52周进行评估。结果:治疗耐受性良好,无不良反应。QuickDASH评分从基线时的20.5分提高到52周时的2.3分,表明疼痛和功能障碍得到改善。在同一时期,右手握力增加29.5%,左手握力增加17.4%。主观上,患者在一年的随访中报告疼痛缓解,功能改善和持续获益。结论:该病例证明了个体化fESWT作为一种安全有效的拇指CMC OA干预措施的潜力,其疼痛和功能的改善持续长达12个月。这些发现支持了fESWT在更大规模对照研究中的进一步研究,并强调了个体化给药策略在临床实践中的重要性。
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引用次数: 0
Promoting agency and communication through powered mobility: a single-group, repeated measures intervention using the explorer mini in toddlers with motor disabilities. 通过动力移动促进代理和交流:使用explorer mini对运动障碍幼儿的单组重复测量干预。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1726259
Gijbels Liesbeth, K A Ingraham, N L Zaino, M E Hoffman, J C Mizrahi, A N Sinclair, B Y Woo, A Fragomeni, A N Meltzoff, K M Steele, H A Feldner, P K Kuhl

Background: Independent mobility in early life catalyzes development across motor, perceptual, cognitive, social, and linguistic domains. For young children with motor disabilities, however, opportunities to explore, interact, and learn from their surroundings are commonly restricted, which may limit developmental progress.

Objective: To examine the effects of a play-based powered mobility intervention, using the Permobil Explorer Mini, on developmental and communicative outcomes in toddlers with motor disabilities, using a single-group, repeated measures design.

Methods: Ten children with motor disabilities (ages 12-36 months) participated in a 12-session intervention in an enriched laboratory environment. The intervention consisted of repeated, play-based sessions using the Explorer Mini, an FDA-cleared powered mobility device. Developmental skills were evaluated pre- and post-intervention using standardized assessments, and language environments were systematically analyzed both in the laboratory and at home.

Results: At baseline, participants scored significantly below age-matched norms across all domains (gross and fine motor, receptive and expressive language, cognitive, adaptive behavior, and social-emotional). Following the intervention, children showed significant raw score gains in cognition, receptive language, fine motor, adaptive behavior, and social-emotional development. Scaled score improvements in cognition and receptive vocabulary indicated growth exceeding expected age-related progression. Analyses of the language environment revealed significant increases in children's expressive vocalizations. Specifically, more frequent joyful ("delight") vocalizations and fewer expressions of distress. Increases in delight vocalizations were further strongly correlated with receptive language gains.

Conclusion: These findings suggest that introducing powered mobility during the toddler period can foster agency, exploration, and communication, catalyzing developmental growth beyond motor function alone. By providing young children with the means to move independently, powered mobility may open new pathways for participation, learning, and connection, laying critical groundwork for more equitable developmental opportunities in early childhood.

背景:生命早期的独立活动促进了运动、知觉、认知、社会和语言领域的发展。然而,对于有运动障碍的幼儿来说,探索、互动和向周围环境学习的机会通常受到限制,这可能会限制他们的发展进步。目的:采用单组重复测量设计,研究使用Permobil Explorer Mini进行基于游戏的动力行动干预对运动障碍幼儿发展和交流结果的影响。方法:10名运动障碍儿童(12-36个月)在丰富的实验室环境中参与了12个阶段的干预。干预包括使用Explorer Mini (fda批准的动力移动设备)重复的、基于游戏的会话。使用标准化评估方法评估干预前后的发展技能,并在实验室和家中系统地分析语言环境。结果:在基线时,参与者在所有领域(粗大和精细运动,接受和表达语言,认知,适应行为和社会情感)的得分明显低于年龄匹配的标准。干预后,儿童在认知、接受性语言、精细运动、适应行为和社会情感发展方面表现出显著的原始得分提高。认知和接受性词汇的评分改善表明增长超出了预期的年龄相关进展。对语言环境的分析显示,儿童的表达能力显著提高。具体来说,就是更频繁地发出快乐的声音,而更少地表达痛苦。喜悦声音的增加与接受性语言的提高进一步密切相关。结论:这些研究结果表明,在幼儿时期引入动力活动可以培养代理、探索和交流能力,促进发育成长,而不仅仅是运动功能。通过为幼儿提供独立行动的手段,动力移动可能为参与、学习和联系开辟新的途径,为幼儿时期更公平的发展机会奠定重要基础。
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引用次数: 0
The effects of extracorporeal shockwave therapy on bone mineral density and microarchitecture in animal models of osteoporosis: a systematic review and meta-analysis. 体外冲击波治疗对骨质疏松动物模型骨密度和微结构的影响:系统综述和荟萃分析。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1731044
Xuelei Wen, Jiahao Xiangli, Qingzheng He, Zhanhai Yin

Objective: This systematic review and meta-analysis aimed to provide the first comprehensive, quantitative assessment of the efficacy of Extracorporeal Shockwave Therapy (ESWT) in improving bone mineral density (BMD) and key trabecular microarchitectural parameters (BV/TV, Tb.Sp, Tb.N, Tb.Th) in animal models of osteoporosis (OP).

Methods: We systematically searched six electronic databases for relevant animal randomized controlled trials (RCTs). Data extraction and quality assessment were performed on the seven studies that met the inclusion criteria. All statistical analyses were conducted using RevMan 5.4.

Results: The meta-analysis revealed that ESWT significantly improved all assessed parameters: (1) a significant increase in BMD [SMD = 2.12, 95% CI (1.50, 2.73), P < 0.00001] with low heterogeneity (I 2 = 0%); (2) a significant increase in bone volume fraction [BV/TV, SMD = 2.26, 95% CI (0.20, 4.32), P = 0.03] with high heterogeneity (I 2 = 76%); (3) a significant decrease in trabecular separation [Tb.Sp, SMD = -1.39, 95% CI (-2.64, -0.14), P = 0.03] with moderate heterogeneity (I 2 = 63%); (4) a significant increase in trabecular number [Tb.N, SMD = 3.51, 95% CI (1.93, 5.10), P < 0.0001] with moderate heterogeneity (I 2 = 62%); and (5) a significant increase in trabecular thickness [Tb.Th, MD = 0.09, 95% CI (0.04, 0.13), P = 0.0005] with low heterogeneity (I 2 = 20%). Although initial heterogeneity for BV/TV, Tb.Sp, and Tb.N was high, sensitivity analysis identified the sources, and their removal resulted in more stable effect estimates.

Conclusion: As the first quantitative synthesis in this field, this study provides preclinical evidence suggesting that ESWT is associated with improvements in bone density and optimizes bone microarchitecture. These findings establish a critical data foundation for ESWT as a potential non-invasive therapy for OP. However, it is important to note that the certainty of these findings is tempered by several factors, including the observed high heterogeneity for BV/TV, Tb.Sp, and Tb.N, the small total sample sizes across outcomes, and the potential for publication bias. The results are further constrained by exclusive reliance on animal models and a limited number of included studies. Future clinical research is required to validate these findings and further elucidate the underlying mechanisms.

目的:本系统综述和荟萃分析旨在首次全面定量评估体外冲击波治疗(ESWT)在改善骨密度(BMD)和关键小梁微结构参数(BV/TV, Tb)方面的疗效。Sp,结核病。N,结核病。骨质疏松动物模型(OP)。方法:系统检索6个电子数据库,检索相关动物随机对照试验(rct)。对符合纳入标准的7项研究进行数据提取和质量评价。所有统计分析均使用RevMan 5.4进行。结果:荟萃分析显示,ESWT显著改善了所有评估参数:(1)BMD显著增加[SMD = 2.12, 95% CI (1.50, 2.73), pi 2 = 0%];(2)骨体积分数显著增加[BV/TV, SMD = 2.26, 95% CI (0.20, 4.32), P = 0.03],异质性高(i2 = 76%);(3)小梁分离明显减少[Tb;Sp, SMD = -1.39, 95% CI (-2.64, -0.14), P = 0.03)和温和的异质性(我2 = 63%);(4)小梁数量显著增加[Tb]。N, SMD = 3.51, 95%可信区间(1.93,5.10),P I 2 = 62%);(5)小梁厚度显著增加[Tb。Th, MD = 0.09, 95% CI (0.04, 0.13), P = 0.0005],异质性较低(i2 = 20%)。尽管BV/TV的初始异质性,Tb。Sp和Tb。N高时,敏感性分析确定了源,它们的去除导致了更稳定的效应估计。结论:本研究首次在该领域进行了定量合成,提供了临床前证据,表明ESWT与改善骨密度和优化骨微结构有关。这些发现为ESWT作为一种潜在的非侵入性治疗op奠定了重要的数据基础。然而,需要注意的是,这些发现的确定性受到几个因素的影响,包括观察到的BV/TV、Tb的高度异质性。Sp和Tb。N,结果的总样本量较小,以及潜在的发表偏倚。由于完全依赖动物模型和纳入的研究数量有限,结果进一步受到限制。未来的临床研究需要验证这些发现,并进一步阐明潜在的机制。
{"title":"The effects of extracorporeal shockwave therapy on bone mineral density and microarchitecture in animal models of osteoporosis: a systematic review and meta-analysis.","authors":"Xuelei Wen, Jiahao Xiangli, Qingzheng He, Zhanhai Yin","doi":"10.3389/fresc.2025.1731044","DOIUrl":"10.3389/fresc.2025.1731044","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review and meta-analysis aimed to provide the first comprehensive, quantitative assessment of the efficacy of Extracorporeal Shockwave Therapy (ESWT) in improving bone mineral density (BMD) and key trabecular microarchitectural parameters (BV/TV, Tb.Sp, Tb.N, Tb.Th) in animal models of osteoporosis (OP).</p><p><strong>Methods: </strong>We systematically searched six electronic databases for relevant animal randomized controlled trials (RCTs). Data extraction and quality assessment were performed on the seven studies that met the inclusion criteria. All statistical analyses were conducted using RevMan 5.4.</p><p><strong>Results: </strong>The meta-analysis revealed that ESWT significantly improved all assessed parameters: (1) a significant increase in BMD [SMD = 2.12, 95% CI (1.50, 2.73), <i>P</i> < 0.00001] with low heterogeneity (<i>I</i> <sup>2</sup> = 0%); (2) a significant increase in bone volume fraction [BV/TV, SMD = 2.26, 95% CI (0.20, 4.32), <i>P</i> = 0.03] with high heterogeneity (<i>I</i> <sup>2</sup> = 76%); (3) a significant decrease in trabecular separation [Tb.Sp, SMD = -1.39, 95% CI (-2.64, -0.14), <i>P</i> = 0.03] with moderate heterogeneity (<i>I</i> <sup>2</sup> = 63%); (4) a significant increase in trabecular number [Tb.N, SMD = 3.51, 95% CI (1.93, 5.10), <i>P</i> < 0.0001] with moderate heterogeneity (<i>I</i> <sup>2</sup> = 62%); and (5) a significant increase in trabecular thickness [Tb.Th, MD = 0.09, 95% CI (0.04, 0.13), <i>P</i> = 0.0005] with low heterogeneity (<i>I</i> <sup>2</sup> = 20%). Although initial heterogeneity for BV/TV, Tb.Sp, and Tb.N was high, sensitivity analysis identified the sources, and their removal resulted in more stable effect estimates.</p><p><strong>Conclusion: </strong>As the first quantitative synthesis in this field, this study provides preclinical evidence suggesting that ESWT is associated with improvements in bone density and optimizes bone microarchitecture. These findings establish a critical data foundation for ESWT as a potential non-invasive therapy for OP. However, it is important to note that the certainty of these findings is tempered by several factors, including the observed high heterogeneity for BV/TV, Tb.Sp, and Tb.N, the small total sample sizes across outcomes, and the potential for publication bias. The results are further constrained by exclusive reliance on animal models and a limited number of included studies. Future clinical research is required to validate these findings and further elucidate the underlying mechanisms.</p>","PeriodicalId":73102,"journal":{"name":"Frontiers in rehabilitation sciences","volume":"6 ","pages":"1731044"},"PeriodicalIF":1.9,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12833336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radial extracorporeal shock wave therapy alters plantar pressure distribution in chronic plantar fasciitis: a biomechanical analysis. 桡骨体外冲击波治疗改变慢性足底筋膜炎患者的足底压力分布:生物力学分析。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-09 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1729608
He Shang, Tao Ma, Yuan Wei, Tianxiang Yang, Jinpeng Liang, Xueqi Liu, Jun Li, Yi Wang, Desheng Chen

Objective: This study aimed to investigate the impact of radial extracorporeal shockwave therapy (rESWT) on plantar pressure distribution in patients with chronic plantar fasciitis (PF). While prior research has established rESWT's clinical efficacy in pain relief, its specific biomechanical effects on plantar loading patterns remain less quantified. This study addresses that gap by providing objective pedobarographic evidence of rESWT-induced pressure redistribution.

Methods: A cohort of 42 patients with unilateral chronic PF was enrolled. Plantar pressure parameters-including total foot pressure, forefoot pressure, rearfoot pressure, peak pressure point, mean pressure, and contact area-were assessed using a plantar pressure measurement system before and after a standardized rESWT protocol. Evaluations compared the affected limb with the contralateral unaffected limb.

Results: Following rESWT, significant changes were observed: on the affected side, forefoot pressure increased (p = 0.001) and rearfoot pressure decreased (p = 0.001); on the unaffected side, forefoot pressure also increased (p = 0.002) and rearfoot pressure decreased (p = 0.003). Total foot pressure decreased on the affected side (p = 0.032) but increased on the unaffected side (p = 0.032). Contact area increased significantly only on the unaffected side (p < 0.001). No significant alterations were found in peak pressure point location or mean pressure (p > 0.05). Effect size analysis (Cohen's d > 0.5) confirmed clinically meaningful improvements in forefoot and rearfoot pressure shifts.

Conclusion: rESWT effectively ameliorates abnormal plantar pressure distribution in PF patients, promoting a forward shift in the pressure center and improving gait symmetry. These findings provide a biomechanical rationale for its clinical use. Future studies should incorporate patient-reported outcomes and longer follow-up to link these biomechanical changes to functional improvement.

目的:探讨桡骨体外冲击波治疗(rESWT)对慢性足底筋膜炎(PF)患者足底压力分布的影响。虽然先前的研究已经确定了rESWT在缓解疼痛方面的临床疗效,但其对足底负荷模式的特定生物力学效应仍然较少量化。本研究通过提供客观的reswt诱导的压力再分布的儿科证据来解决这一差距。方法:纳入42例单侧慢性PF患者。在标准化rESWT方案前后,使用足底压力测量系统评估足底压力参数,包括总足压力、前足压力、后足压力、峰值压力点、平均压力和接触面积。评估比较了患肢和对侧未患肢。结果:经rESWT治疗后,患侧前足压力升高(p = 0.001),后足压力降低(p = 0.001);未受影响侧,前足压力升高(p = 0.002),后足压力降低(p = 0.003)。患侧总足压降低(p = 0.032),未患侧总足压升高(p = 0.032)。接触面积仅在未受影响侧显著增加(p < 0.05)。效应大小分析(Cohen's d > 0.5)证实了前足和后足压力转移的临床意义改善。结论:rESWT能有效改善PF患者的异常足底压力分布,促进压力中心前移,改善步态对称性。这些发现为其临床应用提供了生物力学依据。未来的研究应纳入患者报告的结果和更长时间的随访,以将这些生物力学变化与功能改善联系起来。
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引用次数: 0
Measuring the influence of perceived organizational support, organizational hierarchy culture, strategic human resource management, and psychological empowerment on the return to work. 测量感知组织支持、组织层级文化、战略人力资源管理和心理授权对重返工作的影响。
IF 1.9 Q3 REHABILITATION Pub Date : 2026-01-02 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1679281
Nadra Tawfig, Suhad Farsi, Alaa Lary, Kholod Aggad

In this era of high competition and pandemic, the return to work is challenging because it requires organizations to balance operational demands with individualized support for employees recovering from psychological, physical, and/or personal setbacks. Additionally, managerial expectations, misalignment between workplace culture, and employee readiness can hinder effective reintegration, leading to reduced relapse or productivity. This study aimed to examine the influence of key organizational and psychological factors on employees' return-to-work. A stratified sampling approach was employed to collect data from 370 employees who had successfully returned to work after experiencing work-related injuries and diseases. Eight hypotheses were formulated and validated using structural equation modeling with SmartPLS. Findings from the present study reveal that perceived organizational support has an insignificant impact on the return to work; however, it has a significant impact on strategic human resource management and psychological empowerment. In addition, the present study confirmed a significant impact of organizational hierarchy culture on return-to-work and psychological empowerment. Thus, strategic human resource management had a significant impact on return-to-work rates and psychological empowerment. Finally, psychological empowerment had a significant impact on the return to work. The study highlights the importance of culturally aligned human resource strategies and psychological factors in fostering successful employee reintegration after work absence. These findings have practical implications for human resource professionals and policymakers aiming to design effective, inclusive, and sustainable return-to-work programs tailored to hierarchical organizational environments.

在这个高度竞争和大流行的时代,重返工作岗位是具有挑战性的,因为它要求组织平衡业务需求和个性化支持,以帮助员工从心理、身体和/或个人挫折中恢复过来。此外,管理层的期望、工作场所文化之间的不一致以及员工的准备程度都可能阻碍有效的重新融入,从而降低复发率或生产力。本研究旨在探讨关键组织因素和心理因素对员工重返工作的影响。采用分层抽样方法收集370名因工受伤和患病后成功重返工作岗位的雇员的数据。通过SmartPLS结构方程建模,提出并验证了8个假设。本研究发现,组织支持感对员工重返工作岗位的影响不显著;然而,它对战略人力资源管理和心理赋权有显著的影响。此外,本研究还证实了组织层级文化对重返工作和心理赋权的显著影响。因此,战略人力资源管理对重返工作岗位率和心理赋权有显著影响。最后,心理赋权对重返工作岗位有显著影响。该研究强调了文化上一致的人力资源战略和心理因素在促进员工在缺勤后成功重返社会方面的重要性。这些发现对人力资源专业人士和政策制定者具有实际意义,他们旨在为分层组织环境量身定制有效、包容和可持续的重返工作岗位计划。
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引用次数: 0
Multicomponent exercise interventions for cognitive function in patients with mild cognitive impairment: a summary of best evidence. 多组分运动干预对轻度认知障碍患者的认知功能:最佳证据总结。
IF 1.9 Q3 REHABILITATION Pub Date : 2025-12-19 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1696284
Zhitong Zhang, Jia Wang, Xinhua Qiao, Shan Fu, Liying Ma, Yanli Wang

Aim: This review systematically analyzes and synthesizes evidence on multicomponent training interventions aimed at improving cognitive function in older adults with mild cognitive impairment (MCI). The goal is to inform clinical practice with actionable insights.

Design: Best evidence summary.

Methods: This review adhered to the 6S model to identify evidence, searching data sources from their inception to April 30, 2025. The process involved systematic screening, quality appraisal, and data extraction for evidence synthesis.

Results: A total of 12 sources were included: one guideline, six systematic reviews, one expert consensus, three evidence summaries, and one meta-analysis. From these sources, 24 best-evidence statements were synthesized across six domains: (a) principles for developing multicomponent training prescriptions, (b) intervention effects, (c) exercise dosage and intensity, (d) safety monitoring and risk management, (e) outcome assessment methods, and (f) strategies for promoting implementation and adherence.

Conclusion: The evidence suggests that healthcare professionals should tailor multicomponent training interventions to the individual needs and clinical contexts of older adults with MCI to effectively slow cognitive decline.

Relevance to clinical practice: This synthesis provides an evidence-based framework for developing multicomponent training protocols for older adults with MCI, supporting targeted interventions that may mitigate cognitive deterioration.

Summary: This evidence synthesis integrates 12 high-quality sources, generating 24 best practice recommendations across six critical domains, including prescription design, exercise dosage, and safety management, offering guidance for personalized clinical application.

Systematic review registration: Identifier [ES20257822].

目的:本综述系统分析和综合了旨在改善轻度认知障碍(MCI)老年人认知功能的多组分训练干预的证据。目标是为临床实践提供可操作的见解。设计:最佳证据总结。方法:本综述采用6S模型识别证据,检索从成立到2025年4月30日的数据来源。这一过程包括系统筛选、质量评估和为证据合成而提取数据。结果:共纳入12个来源:1个指南、6个系统综述、1个专家共识、3个证据摘要和1个元分析。从这些来源中,我们综合了六个领域的24个最佳证据陈述:(a)制定多成分训练处方的原则,(b)干预效果,(c)运动剂量和强度,(d)安全监测和风险管理,(e)结果评估方法,以及(f)促进实施和坚持的策略。结论:有证据表明,医疗保健专业人员应根据老年轻度认知损伤患者的个体需求和临床情况量身定制多组分训练干预措施,以有效减缓认知能力下降。与临床实践的相关性:该综合研究提供了一个基于证据的框架,为老年轻度认知损伤患者制定多组分训练方案,支持有针对性的干预措施,可能减轻认知退化。摘要:本证据综合整合了12个高质量来源,在处方设计、运动剂量和安全管理等6个关键领域产生24项最佳实践建议,为个性化临床应用提供指导。系统评价注册:标识符[ES20257822]。
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引用次数: 0
Efficacy of botulinum toxin type A in myogenic temporomandibulardisorders: a single arm, prospective, pilot study. A型肉毒毒素治疗肌源性颞下颌疾病的疗效:单组前瞻性先导研究。
IF 1.9 Q3 REHABILITATION Pub Date : 2025-12-19 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1737706
Bruno Macedo de Sousa, Nansi López-Valverde, Carolina Ferreira, André Mariz de Almeida, Antonio López-Valverde, José A Blanco Rueda

Background: Myogenous temporomandibular disorders (TMDs) is commonly associated with myofascial pain and functional limitations. Botulinum toxin type A (BoNT-A) has shown potential in relieving chronic muscular pain.

Methods: In this single arm, prospective, pilot study, 25 patients diagnosed with myofascial TMDs received a single bilateral intramuscular injection of 50 units of BoNT-A. Assessments using the Visual Analog Scale (VAS), Chronic Pain Index (CPI), Jaw Functional Limitation Scale (JFLS-8), and Oral Health Impact Profile (OHIP-14) were performed at baseline, 6 weeks, and 12 weeks post-treatment.

Results: Significant reductions in pain (VAS: 6.84 ± 1.03 to 0.84 ± 0.94) and CPI (61.87 ± 8.12 to 9.86 ± 4.46) were observed. Functional improvement (JFLS-8: 5.82 ± 0.56 to 1.08 ± 0.51) and enhanced quality of life (OHIP-14: 24.56 ± 8.39 to 5.96 ± 2.79) were also significant. No adverse effects were reported.

Conclusions: BoNT-A showed promising results in reducing pain and improving function in patients with myofascial pain in Temporomandibular Disorders (M-TMDs). However, the single-arm design, small sample size, and short follow-up limit causal inference and external validity. These findings should be interpreted as preliminary.Clinical Trial Registration: Clinicaltrials.gov, identifier NCT05651256.

背景:肌源性颞下颌紊乱(TMDs)通常与肌筋膜疼痛和功能限制有关。A型肉毒毒素(BoNT-A)已显示出缓解慢性肌肉疼痛的潜力。方法:在这项单臂前瞻性先导研究中,25名被诊断为肌筋膜tmd的患者接受单次双侧肌内注射50单位BoNT-A。使用视觉模拟量表(VAS)、慢性疼痛指数(CPI)、颌骨功能限制量表(JFLS-8)和口腔健康影响量表(OHIP-14)在基线、治疗后6周和12周进行评估。结果:患者疼痛(VAS: 6.84±1.03 ~ 0.84±0.94)、CPI(61.87±8.12 ~ 9.86±4.46)明显减轻。功能改善(JFLS-8: 5.82±0.56至1.08±0.51)和生活质量提高(o嘻哈-14:24.56±8.39至5.96±2.79)也有显著性意义。无不良反应报告。结论:BoNT-A在颞下颌疾病(M-TMDs)肌筋膜疼痛患者的减轻疼痛和改善功能方面显示出良好的效果。然而,单臂设计、小样本量和短随访限制了因果推理和外部效度。这些发现应该被解释为初步的。临床试验注册:Clinicaltrials.gov,标识符NCT05651256。
{"title":"Efficacy of botulinum toxin type A in myogenic temporomandibulardisorders: a single arm, prospective, pilot study.","authors":"Bruno Macedo de Sousa, Nansi López-Valverde, Carolina Ferreira, André Mariz de Almeida, Antonio López-Valverde, José A Blanco Rueda","doi":"10.3389/fresc.2025.1737706","DOIUrl":"10.3389/fresc.2025.1737706","url":null,"abstract":"<p><strong>Background: </strong>Myogenous temporomandibular disorders (TMDs) is commonly associated with myofascial pain and functional limitations. Botulinum toxin type A (BoNT-A) has shown potential in relieving chronic muscular pain.</p><p><strong>Methods: </strong>In this single arm, prospective, pilot study, 25 patients diagnosed with myofascial TMDs received a single bilateral intramuscular injection of 50 units of BoNT-A. Assessments using the Visual Analog Scale (VAS), Chronic Pain Index (CPI), Jaw Functional Limitation Scale (JFLS-8), and Oral Health Impact Profile (OHIP-14) were performed at baseline, 6 weeks, and 12 weeks post-treatment.</p><p><strong>Results: </strong>Significant reductions in pain (VAS: 6.84 ± 1.03 to 0.84 ± 0.94) and CPI (61.87 ± 8.12 to 9.86 ± 4.46) were observed. Functional improvement (JFLS-8: 5.82 ± 0.56 to 1.08 ± 0.51) and enhanced quality of life (OHIP-14: 24.56 ± 8.39 to 5.96 ± 2.79) were also significant. No adverse effects were reported.</p><p><strong>Conclusions: </strong>BoNT-A showed promising results in reducing pain and improving function in patients with myofascial pain in Temporomandibular Disorders (M-TMDs). However, the single-arm design, small sample size, and short follow-up limit causal inference and external validity. These findings should be interpreted as preliminary.<b>Clinical Trial Registration</b>: Clinicaltrials.gov, identifier NCT05651256.</p>","PeriodicalId":73102,"journal":{"name":"Frontiers in rehabilitation sciences","volume":"6 ","pages":"1737706"},"PeriodicalIF":1.9,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a mobile app-based biofeedback breathing exercise program on handgrip strength, respiratory muscle activity, and pulmonary function in healthy adults. 基于移动应用程序的生物反馈呼吸运动程序对健康成人握力、呼吸肌活动和肺功能的影响
IF 1.9 Q3 REHABILITATION Pub Date : 2025-12-18 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1696503
Tae-Woo Kang, Seo-Yoon Park, Hee-Jin Jo

Introduction: This study investigated the effects of a mobile app-based biofeedback breathing exercise program on handgrip strength, respiratory muscle activity, and pulmonary function in healthy young adults.

Methods: Forty-eight participants were randomly assigned to an experimental group (n = 22), which performed app-based biofeedback breathing exercises, or a control group (n = 26), which performed traditional breathing exercises. Both groups completed three to four sessions per week for four weeks. Handgrip strength, respiratory muscle activity measured using surface electromyography, and pulmonary function assessed by spirometry were evaluated before and after the intervention.

Results: The experimental group showed a significant within-group improvement in handgrip strength (p < 0.05), although between-group differences were not significant. Significant reductions in external intercostal and rectus abdominis activity were observed in the experimental group (p < 0.05), whereas the control group demonstrated reduced external oblique activity (p < 0.05). Both groups improved in forced expiratory volume in one second (FEV₁) and in the FEV₁/forced vital capacity (FVC) ratio (p < 0.05), with a greater improvement in FEV₁/FVC observed in the experimental group.

Discussion: These findings suggest that mobile app-based biofeedback breathing exercises may enhance respiratory efficiency and optimize muscle activation patterns in healthy young adults, supporting their potential use as an accessible adjunct tool in pulmonary rehabilitation.

本研究调查了基于移动应用程序的生物反馈呼吸运动程序对健康年轻人握力、呼吸肌活动和肺功能的影响。方法:48名参与者被随机分为实验组(n = 22)和对照组(n = 26),实验组进行基于应用程序的生物反馈呼吸练习,对照组进行传统呼吸练习。两组人每周完成三到四次训练,持续四周。干预前后分别评估握力、表面肌电图测量的呼吸肌活动和肺活量测定法评估的肺功能。结果:实验组握力组内差异有统计学意义(p < 0.05),但组间差异无统计学意义。实验组外肋间肌和腹直肌活动明显减少(p < 0.05),而对照组外斜肌活动明显减少(p < 0.05)。两组1秒用力呼气量(FEV₁)和用力肺活量(FVC)比均有改善(p < 0.05),实验组FEV₁/FVC改善更大。讨论:这些发现表明,基于移动应用程序的生物反馈呼吸练习可以提高健康年轻人的呼吸效率,优化肌肉激活模式,支持其作为肺部康复辅助工具的潜在用途。
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引用次数: 0
Effectiveness of post-acute care for patients with cerebral vascular disease in Taiwan between 2014 and 2023: a narrative synthesis. 2014 - 2023年台湾脑血管病患者急性期后护理效果:叙事综合
IF 1.9 Q3 REHABILITATION Pub Date : 2025-12-16 eCollection Date: 2025-01-01 DOI: 10.3389/fresc.2025.1667253
Cheng-Che Wu, Chang-Cheng Wu, Kuan-Chia Lin

Objectives: To explore the overall effectiveness of the Post-Acute Care-Cerebrovascular Diseases (PAC-CVD) program in Taiwan, which was implemented in 2014.

Data sources: A systematic search of databases, namely PubMed and Google Scholar, was conducted. Eligible studies published between Jan 2014 and June 2023 were included.

Study selection: Studies included those that explored stroke care, involved post-acute care, were conducted in Taiwan, focused on an inpatient model of the PAC-CVD program, and had either a quantitative or qualitative design. In total, 23 articles were identified and included for narrative synthesis after complete examination.

Data extraction: Multiple observers independently extracted the research articles, with their objectives focused on topics such as patient outcomes, quality of care, the influence of referral systems, cost-effectiveness, or outcome prediction for the PAC-CVD program.

Data synthesis: The PAC groups showed significantly better performance in most functional outcome, quality of care, and cost-effectiveness indicators than the non-PAC groups. Patients with intra-hospital referrals or in partner hospitals had better outcomes. Younger age, ischemic stroke, and better baseline condition, especially in balance function, were strong predictive factors for stroke prognosis in the PAC program.

Conclusions: The PAC-CVD program, implemented in Taiwan through the establishment of an integrated healthcare system and a change in payment systems, not only enhanced functional recovery and quality of life of acute stroke patients but also improved the quality of health care. The program also offered a more efficient and effective care model for acute stroke patients by reducing medical expenditures. However, the PAC program has also increased the workload of clinical healthcare professionals. The successful PAC-CVD implementation indicates the possibility of a standard rehabilitative care model for acute stroke patients, with expansion to other diseases or conditions possible after adjustments to the payment structure and workload.

目的:探讨2014年实施的台湾地区急性期后护理-脑血管病(PAC-CVD)项目的整体效果。数据来源:系统检索PubMed和谷歌Scholar数据库。纳入了2014年1月至2023年6月间发表的符合条件的研究。研究选择:研究包括在台湾进行的探讨卒中护理,涉及急性期后护理的研究,重点是PAC-CVD计划的住院模型,并采用定量或定性设计。在全面审查后,共确定并纳入23篇文章进行叙述综合。数据提取:多个观察者独立提取研究文章,其目标集中在诸如PAC-CVD项目的患者结果、护理质量、转诊系统的影响、成本效益或结果预测等主题上。数据综合:PAC组在大多数功能结果、护理质量和成本效益指标上的表现明显优于非PAC组。院内转诊或合作医院的患者预后较好。在PAC项目中,较年轻的年龄、缺血性卒中和较好的基线状况,特别是平衡功能,是卒中预后的重要预测因素。结论:通过建立综合医疗体系和改变支付制度,在台湾实施PAC-CVD计划,不仅可以促进急性脑卒中患者的功能恢复和生活质量,而且可以提高医疗质量。该项目还通过减少医疗支出,为急性中风患者提供了一种更高效、更有效的护理模式。然而,PAC计划也增加了临床医疗保健专业人员的工作量。PAC-CVD的成功实施表明,急性脑卒中患者有可能建立标准的康复护理模式,在调整支付结构和工作量后,可能扩展到其他疾病或病症。
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引用次数: 0
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Frontiers in rehabilitation sciences
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