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Advancing Community-Based Participatory Research to Address Health Disparities in Hawai'i: Perspectives from Academic Researchers. 推进社区参与性研究以解决夏威夷的健康差异:来自学术研究人员的观点。
Katherine I Yang, Jane J Chung-Do, Loren Fujitani, Alyssa Foster, Shannon Mark, Yuito Okada, Zeyana Saad-Jube, Fadi Youkhana, Kathryn L Braun, Kevin Cassel, Susana Helm, Lana Sue Ka'opua, Peter J Mataira, Christy Nishita, Scott K Okamoto, Claire Townsend Ing, Kristine Qureshi, Karen Umemoto

Community-based participatory research (CBPR) continues to be recognized as an effective research approach in which academic researchers work in partnership with communities to address health disparities. Although the literature suggests benefits associated with CBPR, more needs to be done to advance CBPR to ultimately reduce health disparities. Hawai'i presents a research-rich opportunity for CBPR because of its ethnic diversity and geographic location, resulting in close-knit communities with unique experiences and concerns. This study aims to better understand the experiences of academic researchers who are conducting CBPR in Hawai'i and their perceptions of its benefits and challenges as well as recommendations to advance the field. Twelve academic researchers with Hawai'i-based CBPR experience were interviewed. Four major themes emerged from their responses: the importance of prioritizing relationship-building; reciprocal learning and other benefits of CBPR; navigating the tensions between CBPR and funding priorities; and building an academic setting that supports CBPR. Increasing awareness of CBPR and its benefits, as well as transforming the culture in all spaces where CBPR occurs may maximize its potential to ultimately promote health equity.

基于社区的参与性研究(CBPR)继续被认为是一种有效的研究方法,学术研究人员与社区合作,解决健康差异问题。虽然文献表明与CBPR相关的益处,但需要做更多的工作来推进CBPR,最终减少健康差距。夏威夷为CBPR提供了丰富的研究机会,因为它的种族多样性和地理位置,形成了具有独特经验和关注的紧密联系的社区。本研究旨在更好地了解在夏威夷进行CBPR的学术研究人员的经验,以及他们对其好处和挑战的看法,以及推进该领域的建议。采访了12位具有夏威夷CBPR经验的学术研究人员。他们的回答中出现了四个主要主题:优先考虑建立关系的重要性;互惠学习和CBPR的其他好处;应对CBPR与资金优先事项之间的紧张关系;建立一个支持CBPR的学术环境。提高对CBPR及其益处的认识,以及改变发生CBPR的所有空间的文化,可最大限度地发挥其潜力,最终促进卫生公平。
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引用次数: 0
Ill-defined Causes of Death in the Republic of Kiribati, 2005 to 2014. 2005年至2014年基里巴斯共和国不明确的死亡原因。
Maryanne Utiera, Kerri Viney, Karen Bissell, Sharon Biribo, Kantaake Corbett, Eretii Timeon, Burentau Teriboriki, Tebikau Tibwe

This was a retrospective descriptive study of deaths in the Republic of Kiribati from 2005 to 2014. We determined the proportion of all deaths that are ill-defined and described the characteristics of these ill-defined deaths. There were 5618 deaths between 2005 to 2014; of these 1049 (18.7%) were ill-defined. Of these, 576 (54.9%) were male. Those aged 65 years and above had the highest proportion of ill-defined deaths at 40% (n= 415), followed by children aged 0-15 years (29.6%, n=310). Further, 47.7% (n=500) of ill-defined deaths were reported by staff from health dispensaries. When the ill-defined deaths were further categorised according to their R code (with the R code being a group of ill-defined deaths, with sub-groups), 30.5% (n=320) had unknown cause of death, while 29.3% (n=307) had general symptoms and signs. Almost one fifth of deaths in Kiribati were ill-defined, indicating that the reporting on cause of death can be improved through Medical Certification on Causes of Death training and by other means. Improved cause of death reporting will allow the Ministry of Health and Medical Services to better allocate resources, plan health care service delivery and support the development of evidence based preventative and curative policies.

这是一项对基里巴斯共和国2005年至2014年死亡人数的回顾性描述性研究。我们确定了所有不明确死亡的比例,并描述了这些不明确死亡的特征。2005年至2014年间,有5618人死亡;其中1049例(18.7%)定义不清。其中男性576人(54.9%)。65岁及以上的人死亡不明确的比例最高,为40% (n= 415),其次是0-15岁的儿童(29.6%,n=310)。此外,47.7% (n=500)定义不明确的死亡是由诊所工作人员报告的。当根据其R代码(R代码为一组定义不清的死亡,再加上子组)进一步分类时,30.5% (n=320)的死亡原因不明,而29.3% (n=307)的死亡有一般症状和体征。基里巴斯近五分之一的死亡是不明确的,这表明可以通过死亡原因医学证明培训和其他方式改进死亡原因的报告。改进死因报告将使卫生和医疗服务部能够更好地分配资源,规划保健服务的提供,并支持制定基于证据的预防和治疗政策。
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引用次数: 0
Patient Perspectives in Comparing Hospitals for Childbirth: Insights from Hawai'i. 比较分娩医院的患者观点:来自夏威夷的见解。
Charmaine Milla, Mary Guo, Ann Chang, Nancy Chen, Jill Miyamura, Tetine Sentell

Childbirth is a national priority area for healthcare quality improvement. Patient perspectives are increasingly valued in healthcare, yet Asian American and Pacific Islander (AAPI) perspectives of healthcare quality are often understudied, particularly from individuals with limited English proficiency (LEP). Our study goal was to understand factors that consumers in Hawai'i, including AAPI and those with LEP, use to compare patient care in hospitals, especially for childbirth. A total of 400 women ages 18 years and older with a recent childbirth completed an in-person interview in English (n=291), Tagalog (n=42), Chinese (n=36), or Marshallese (n=31) on O'ahu, Hawai'i. Participants described if (yes/no), and how (open-ended), they believed hospitals in the state varied in providing patient care. Open-ended responses were coded by two independent raters using the framework approach. Respondents were 53.3% Asian, 30.8% Pacific Islander, 13.5% White, and 2.5% other race/ethnicity; 17.8% reported limited English proficiency. Overall, 66.8% of respondents affirmed that local hospitals varied in patient care; Marshallese, other Pacific Islanders, and non-English speakers were significantly less likely to say that Hawai'i hospitals varied in patient care. Among those who endorsed hospital variation, commonly reported themes about this variation were: (1) patient experience, (2) patient overall impression, (3) childbirth options (eg, waterbirths), (4) staff, (5) facilities (eg, "emergency capabilities"), (6) high-tech levels of care, and (7) the hospital's area of focus (eg, "women and children"). We provide insights into factors that diverse patients use to compare patient care in hospitals in Hawai'i to add value, relevance, and engagement to healthcare quality research and dissemination efforts.

生育是提高保健质量的国家优先领域。在医疗保健中,患者的观点越来越受到重视,但亚裔美国人和太平洋岛民(AAPI)对医疗保健质量的观点往往研究不足,尤其是英语水平有限(LEP)的个体。我们的研究目标是了解夏威夷消费者,包括AAPI和LEP患者,用来比较医院患者护理的因素,特别是分娩。在夏威夷的奥胡岛,共有400名年龄在18岁及以上、最近分娩的妇女用英语(291名)、他加禄语(42名)、中文(36名)或马绍尔语(31名)完成了面对面访谈。参与者描述了是否(是/否),以及他们认为该州的医院在提供病人护理方面存在差异(开放式)。开放式回答由两个独立的评分员使用框架方法进行编码。受访者中亚洲人占53.3%,太平洋岛民占30.8%,白人占13.5%,其他种族占2.5%;17.8%的人表示英语水平有限。总体而言,66.8%的受访者肯定当地医院在患者护理方面存在差异;马绍尔人、其他太平洋岛民和非英语人士认为夏威夷医院在病人护理方面存在差异的可能性要小得多。在那些支持医院变化的人中,通常报告的关于这种变化的主题是:(1)患者体验,(2)患者总体印象,(3)分娩选择(例如,水中分娩),(4)工作人员,(5)设施(例如,“应急能力”),(6)高科技护理水平,以及(7)医院的重点领域(例如,“妇女和儿童”)。我们提供了不同患者用于比较夏威夷医院患者护理的因素的见解,以增加医疗保健质量研究和传播工作的价值、相关性和参与度。
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引用次数: 0
Hawai'i Journal Watch: Highlights of recent research from the University of Hawai'i and the Hawai'i State Department of Health. 《夏威夷杂志观察》:夏威夷大学和夏威夷州卫生部最近的研究亮点。
Karen Rowan
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引用次数: 0
Insights in Public Health: Hana Pu No Ke Ola O Hana ("Working Together for the Health of Hana"): Our 14-year CBPR Journey. 公共卫生洞察:Hana Pu No Ke Ola O Hana(“为Hana的健康而努力”):我们14年的CBPR之旅。
May Vawer, Rick Rutiz, Viliami Tukuafu, Kirsten Whatley, Kauwila Hanchett, Lipoa Kahaleuahi, Lehualani Park, Mikala Minn, Beth Blackburn, Malia Young, Ann Muneno, Deborah A Taira, Tetine Sentell, Todd B Seto

There are substantial and persistent health disparities among Native Hawaiians that are best addressed through multilevel socio-ecological approaches, which are tailored to the needs of the community. Partnerships that link academic investigators with grass roots community members have the potential to profoundly reduce health disparities and improve health and wellness by increasing the capacity of community-based organizations to provide leadership in health advocacy, support community health promotion, and participate in health research. We describe a 14-year partnership to reduce Native Hawaiian health disparities between investigators from The Queen's Medical Center and University of Hawai'i John A. Burns School of Medicine (QMC-JABSOM) and community members in Hana, a geographically isolated, underserved, rural community with the second largest concentration of Native Hawaiians in the state. Our relationship started as an investigator-initiated, National Institutes of Health-sponsored study to explore familial cardiomyopathy, and transitioned to a community-based project that combined community cardiovascular health screening fairs with a qualitative research study to understand attitudes towards genetic research. Most recently, QMC-JABSOM has partnered closely with Ma Ka Hana Ka 'Ike, an award-winning construction skills training program for at-risk youth in Hana, to develop innovative, culturally based interventions to improve health and well-being among Native Hawaiians using principles of community-based participatory research.

夏威夷土著居民之间存在着巨大而持久的健康差距,最好通过针对社区需要的多层次社会生态方法加以解决。将学术调查人员与基层社区成员联系起来的伙伴关系有可能通过提高社区组织在卫生宣传、支持社区卫生促进和参与卫生研究方面发挥领导作用的能力,大大减少卫生差距并改善健康和保健。我们描述了一项为期14年的合作伙伴关系,旨在减少皇后医学中心和夏威夷大学约翰·a·伯恩斯医学院(QMC-JABSOM)的研究人员与哈纳社区成员之间的夏威夷原住民健康差距,哈纳是一个地理上孤立的、服务不足的农村社区,是该州夏威夷原住民的第二大集中地。我们的关系开始于一个研究者发起的,由美国国立卫生研究院赞助的探索家族性心肌病的研究,并转变为一个基于社区的项目,该项目将社区心血管健康筛查博览会与定性研究结合起来,以了解对基因研究的态度。最近,QMC-JABSOM与Ma Ka Hana Ka 'Ike密切合作,Ma Ka Hana Ka 'Ike是一个屡获殊荣的建筑技能培训项目,旨在为Hana的高危青年开发创新的、基于文化的干预措施,利用基于社区的参与性研究原则,改善夏威夷原住民的健康和福祉。
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引用次数: 0
Potential of Fucoidan From Brown Seaweeds (Sargassum sp.) as Innovation Therapy on Breast Cancer 褐藻褐藻聚糖作为乳腺癌创新疗法的潜力
Agung B S Satyarsa
Breast cancer is a non-communicable disease and a major health problem in the world. Based on the data from WHO in 2012, the incidence of breast cancer is reported as 1.67 million cases. One cause of the highest morbidity and mortality in breast cancer is chemoresistance. Various attempts were made to solve this problem. The purpose of this review is to describe the potential of fucoidan from brown seaweeds (Sargassum sp.) as innovation therapy on breast cancer. Fucoidan as proapoptotic agents affect many target cells (multi-targets) to induce apoptosis. Fucoidan has a potential for a new treatment of breast cancer because of its potent proapoptotic and anti-metastatic properties. However, no research has yet evaluated this in clinical trial. Hence,  further studies are needed to confirm the true potential of fucoidan from brown seaweeds as therapy for breast cancer.     Keywords: anti-proliferative agents, pro-apoptotic agents, fucoidan, breast cancer
乳腺癌是一种非传染性疾病,也是世界上的一个主要健康问题。根据世卫组织2012年的数据,乳腺癌的发病率报告为167万例。乳腺癌发病率和死亡率最高的一个原因是化疗耐药性。人们作了各种尝试来解决这个问题。本综述的目的是描述褐海藻褐藻聚糖作为乳腺癌创新疗法的潜力。岩藻糖聚糖作为促凋亡剂作用于多个靶细胞(多靶点)诱导细胞凋亡。岩藻糖聚糖因其有效的促细胞凋亡和抗转移特性而具有治疗乳腺癌的新潜力。然而,尚未有研究在临床试验中对其进行评估。因此,需要进一步的研究来证实褐海藻褐藻聚糖作为乳腺癌治疗的真正潜力。关键词:抗增殖药物,促凋亡药物,岩藻聚糖,乳腺癌
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引用次数: 5
Clinical Manifestation of Peripheral Artery Disease in Type 2 Diabetes Melitus with Ankle Branchial Index Measurement 踝支指数测定对2型糖尿病外周动脉病变的临床表现
Winny W Nasution, H. Heryaman, J. W. Martha, A. Ridwan
Diabetes mellitus (DM) is a metabolic disease that has a high prevalence in Asia, including Indonesia. One of the complications of DM is Peripheral Artery Disease (PAP). Ankle Brachial Index (ABI) measurement is a simple and non-invasive methods that can be used for PAP evaluation. This study aims to provide an overview of the clinical manifestations of PAP and the value of ABI as early detection of PAP in patients with type-2 DM. This research uses quantitative descriptive design studies. The research variables used to assess PAP were ABI values, age, sex, duration of diabetes mellitus, hypertension, and clinical manifestations of PAP such as pain, intermittent claudication, muscle atrophy, skin discoloration, sweating, wound healing impairment, and gangrene. This study involved 92 research subjects. From the study we found out that the normal ABI value and the ABI value of the PAP category in patients with type 2 diabetes were 91.3% and 7.6%. The ABI value of the PAP category in DM patients is more commonly found in women (6.5%), adult patients (5.4%), duration of DM up to 2 years (5.4%), and with hypertension (5.4%) . Pain and numbness are the most common clinical manifestations of PAP in DM patients.     Keywords: diabetes mellitus, ankle brachial index, peripheral artery disease.
糖尿病(DM)是一种代谢性疾病,在包括印度尼西亚在内的亚洲有很高的患病率。外周动脉病变(PAP)是糖尿病的并发症之一。踝肱指数(Ankle Brachial Index, ABI)测量是一种简单、无创的PAP评估方法。本研究旨在概述PAP的临床表现,以及ABI在2型糖尿病患者PAP早期检测中的价值。本研究采用定量描述性设计研究。用于评估PAP的研究变量为ABI值、年龄、性别、糖尿病病程、高血压以及PAP的临床表现,如疼痛、间歇性跛行、肌肉萎缩、皮肤变色、出汗、伤口愈合障碍和坏疽。这项研究涉及92名研究对象。通过研究我们发现,2型糖尿病患者PAP类别的正常ABI值和ABI值分别为91.3%和7.6%。糖尿病患者PAP类别的ABI值更常见于女性(6.5%)、成人(5.4%)、糖尿病持续2年以上(5.4%)和高血压(5.4%)。疼痛和麻木是DM患者PAP最常见的临床表现。关键词:糖尿病,踝肱指数,外周动脉疾病。
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引用次数: 1
Hypolipidemic Effects of Pea Protein Hydrolysates on Lipid Profile and Uric Acid in Cisplatin-Induced Nephropathy Rats 豌豆蛋白水解物对顺铂肾病大鼠血脂和尿酸的降血脂作用
Meilinah Hidayat, S. Prahastuti, A. A. Soemardji, Khomaini Hasan, G. Audrey, Janifer Gabriella, Petrisia Luvina, Cicilia Liempapas
The usage of Cisplatin (CP) can cause side effects such as toxicity and impaired kidneyfunction. Poor kidney function causes dyslipidemia and hyperuricemia. Researchers in Canadastate that pea protein hydrolysates can improve kidney function. The aim was to examine thehypolipidemic effect of 8 types of pea protein hydrolysate on lipid profiles and uric acid in CPinduced rats in purpose to find protein sources origin of Indonesia for kidney therapy. This is atrue experimental study using fifty female Wistar rats divided into 10 treatment groups.Weadministered 8 types of pea protein hydrolysate for 30 days. On day 7 all rats (except negativecontrol) were induced CP intraperitoneally. Study parameters was evaluated on days 12 and30. In general, all treatments showed good hypolipidemic effects, and differed significantly fromCP group (p <0.01). The group that showed lowest total cholesterol, LDL and triglycerideresults is yellow pea protein hydrolysate Neutrase; HDL: green peas protein hydrolysatebromelain, uric acid: protein hydrolysate of pea protein isolate bromelain. As conclusion,protein hydrolysates of pea has good hypolipidemic effects on Lipid profile and Uric Acid inCP-induced nephropathy Rats. Keywords: protein hydrolysates, green peas, neutrase, bromelain, lipid profiles
顺铂(CP)的使用可引起副作用,如毒性和肾功能受损。肾功能不佳导致血脂异常和高尿酸血症。加拿大的研究人员指出,豌豆蛋白水解物可以改善肾功能。目的是研究8种豌豆蛋白水解物对cp诱导大鼠血脂和尿酸的降血脂作用,以寻找印度尼西亚来源的蛋白质用于肾脏治疗。这是一项真实的实验研究,用50只雌性Wistar大鼠分为10个治疗组。我们连续30天服用8种豌豆蛋白水解物。第7天,除阴性对照组外,所有大鼠均腹腔诱导CP。在第12天和第30天评估研究参数。总体而言,各治疗组降血脂效果均较好,与mcp组比较差异有统计学意义(p <0.01)。总胆固醇、低密度脂蛋白和甘油三酯水平最低的组是黄豌豆蛋白水解物中和酶;HDL:青豆蛋白水解菠萝蛋白酶,尿酸:豌豆分离蛋白水解菠萝蛋白酶。由此可见,豌豆蛋白水解物对incp肾病大鼠的血脂和尿酸具有良好的降血脂作用。关键词:蛋白水解物,青豆,中和酶,菠萝蛋白酶,脂质谱
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引用次数: 0
Milk Consumption Correlates with Body Height in Children 牛奶摄入量与儿童身高相关
Evan Tirtasaputra, Grace Puspasari, T. Lucretia
Growth in children is very important because it affects a person's height as an adult.Qualified and adequate nutrition play a significant role in growth. Adequate milk consumptioncan affect bone growth which ultimately affects height and helps reduce the risk of bone loss.The purpose of this study was to determine the correlation between milk consumption andheight in children. This study is an analytic observational study, involving 126 subjects aged 6-9 years from an elementary school in Bandung. The sample was taken by whole samplingtechnique. Data collection was carried out using questionnaires and height measurements. Thedata was analyzed using the Gamma correlation test. The statistical results showed a significantrelationship between the frequency of milk consumption and height (p = 0.044) with a mediumcorrelation coefficient (r = 0.430) and a positive correlation direction which meant an increasein the frequency of milk consumption along with the increasing height in children aged 6-9years. We concluded that milk consumption correlates with body height in children.Keywords: milk consumption, body height, children, correlation
儿童的成长非常重要,因为它会影响一个人成年后的身高。合格和充足的营养在生长中起着重要作用。摄入足够的牛奶会影响骨骼生长,最终影响身高,并有助于降低骨质流失的风险。这项研究的目的是确定牛奶摄入量与儿童身高之间的关系。本研究为分析性观察性研究,选取万隆市某小学6-9岁的126名被试。样品采用全采样技术采集。数据收集采用问卷调查和身高测量。使用Gamma相关检验对数据进行分析。统计结果显示,6 ~ 9岁儿童的牛奶消费频率与身高呈显著相关(p = 0.044),呈中等相关(r = 0.430),呈正相关方向,即随着身高的增加,牛奶消费频率增加。我们的结论是,牛奶的摄入量与儿童的身高有关。关键词:牛奶消费量,身高,儿童,相关性
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引用次数: 1
Association between Fever during Admission and Outcome of Treatment in Tuberculous Meningitis Patients in Hasan Sadikin General Hospital Bandung 万隆哈桑萨迪金总医院结核性脑膜炎患者入院时发热与治疗结果的关系
Regita A Kuswanto, A. Rizal, R. Koesoemadinata
Tuberculous meningitis (TBM) is the most common type of meningitis with a highmortality rate (20-41%). There are limited data on factors associated with outcome oftreatment, especially in Indonesia. Fever is a common inflammatory process in meningitispatients. This study aims to investigate the association between fever during admission andoutcome of treatment in TBM patients treated in the In-patient Neurology Department at HasanSadikin Hospital Bandung. This is an observational retrospective cohort study conducted byusing medical records from 2017. The inclusion criteria of this study were all medical recordsof inpatients who were diagnosed as TBM and ?18 years old, while the exclusion criteria wereincomplete medical records. The variables in this study were age, gender, body temperature,classification of TBM, and Glasglow Outcome Scale (GOS). There were 125 medical recordswhich fulfilled the inclusion criteria. Kruskal- Wallis test showed that fever was notsignificantly associated with GOS (p=0.193). In conclusion, fever during admission was notassociated with GOS in TBM patients.Keywords: tuberculous meningitis, fever, Glasglow Outcome Scale, outcome
结核性脑膜炎(TBM)是最常见的脑膜炎类型,死亡率高(20-41%)。与治疗结果相关的因素数据有限,特别是在印度尼西亚。发烧是脑膜炎患者常见的炎症过程。本研究旨在探讨万隆市HasanSadikin医院神经内科收治的TBM患者入院时发热与治疗结果的关系。这是一项观察性回顾性队列研究,利用2017年的医疗记录进行。本研究的纳入标准为所有诊断为TBM且未满18岁的住院患者的病历,排除标准为不完整的病历。本研究的变量为年龄、性别、体温、TBM分类、Glasglow Outcome Scale (GOS)。有125份病历符合纳入标准。Kruskal- Wallis检验显示发热与GOS无显著相关性(p=0.193)。综上所述,TBM患者入院时发热与GOS无关。关键词:结核性脑膜炎,发热,Glasglow结局量表,结局
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引用次数: 0
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Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health
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