Katherine I Yang, Jane J Chung-Do, Loren Fujitani, Alyssa Foster, Shannon Mark, Yuito Okada, Zeyana Saad-Jube, Fadi Youkhana, Kathryn L Braun, Kevin Cassel, Susana Helm, Lana Sue Ka'opua, Peter J Mataira, Christy Nishita, Scott K Okamoto, Claire Townsend Ing, Kristine Qureshi, Karen Umemoto
Community-based participatory research (CBPR) continues to be recognized as an effective research approach in which academic researchers work in partnership with communities to address health disparities. Although the literature suggests benefits associated with CBPR, more needs to be done to advance CBPR to ultimately reduce health disparities. Hawai'i presents a research-rich opportunity for CBPR because of its ethnic diversity and geographic location, resulting in close-knit communities with unique experiences and concerns. This study aims to better understand the experiences of academic researchers who are conducting CBPR in Hawai'i and their perceptions of its benefits and challenges as well as recommendations to advance the field. Twelve academic researchers with Hawai'i-based CBPR experience were interviewed. Four major themes emerged from their responses: the importance of prioritizing relationship-building; reciprocal learning and other benefits of CBPR; navigating the tensions between CBPR and funding priorities; and building an academic setting that supports CBPR. Increasing awareness of CBPR and its benefits, as well as transforming the culture in all spaces where CBPR occurs may maximize its potential to ultimately promote health equity.
{"title":"Advancing Community-Based Participatory Research to Address Health Disparities in Hawai'i: Perspectives from Academic Researchers.","authors":"Katherine I Yang, Jane J Chung-Do, Loren Fujitani, Alyssa Foster, Shannon Mark, Yuito Okada, Zeyana Saad-Jube, Fadi Youkhana, Kathryn L Braun, Kevin Cassel, Susana Helm, Lana Sue Ka'opua, Peter J Mataira, Christy Nishita, Scott K Okamoto, Claire Townsend Ing, Kristine Qureshi, Karen Umemoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Community-based participatory research (CBPR) continues to be recognized as an effective research approach in which academic researchers work in partnership with communities to address health disparities. Although the literature suggests benefits associated with CBPR, more needs to be done to advance CBPR to ultimately reduce health disparities. Hawai'i presents a research-rich opportunity for CBPR because of its ethnic diversity and geographic location, resulting in close-knit communities with unique experiences and concerns. This study aims to better understand the experiences of academic researchers who are conducting CBPR in Hawai'i and their perceptions of its benefits and challenges as well as recommendations to advance the field. Twelve academic researchers with Hawai'i-based CBPR experience were interviewed. Four major themes emerged from their responses: the importance of prioritizing relationship-building; reciprocal learning and other benefits of CBPR; navigating the tensions between CBPR and funding priorities; and building an academic setting that supports CBPR. Increasing awareness of CBPR and its benefits, as well as transforming the culture in all spaces where CBPR occurs may maximize its potential to ultimately promote health equity.</p>","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"78 3","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401203/pdf/hjmph7803_0083.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37042355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This was a retrospective descriptive study of deaths in the Republic of Kiribati from 2005 to 2014. We determined the proportion of all deaths that are ill-defined and described the characteristics of these ill-defined deaths. There were 5618 deaths between 2005 to 2014; of these 1049 (18.7%) were ill-defined. Of these, 576 (54.9%) were male. Those aged 65 years and above had the highest proportion of ill-defined deaths at 40% (n= 415), followed by children aged 0-15 years (29.6%, n=310). Further, 47.7% (n=500) of ill-defined deaths were reported by staff from health dispensaries. When the ill-defined deaths were further categorised according to their R code (with the R code being a group of ill-defined deaths, with sub-groups), 30.5% (n=320) had unknown cause of death, while 29.3% (n=307) had general symptoms and signs. Almost one fifth of deaths in Kiribati were ill-defined, indicating that the reporting on cause of death can be improved through Medical Certification on Causes of Death training and by other means. Improved cause of death reporting will allow the Ministry of Health and Medical Services to better allocate resources, plan health care service delivery and support the development of evidence based preventative and curative policies.
{"title":"Ill-defined Causes of Death in the Republic of Kiribati, 2005 to 2014.","authors":"Maryanne Utiera, Kerri Viney, Karen Bissell, Sharon Biribo, Kantaake Corbett, Eretii Timeon, Burentau Teriboriki, Tebikau Tibwe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This was a retrospective descriptive study of deaths in the Republic of Kiribati from 2005 to 2014. We determined the proportion of all deaths that are ill-defined and described the characteristics of these ill-defined deaths. There were 5618 deaths between 2005 to 2014; of these 1049 (18.7%) were ill-defined. Of these, 576 (54.9%) were male. Those aged 65 years and above had the highest proportion of ill-defined deaths at 40% (n= 415), followed by children aged 0-15 years (29.6%, n=310). Further, 47.7% (n=500) of ill-defined deaths were reported by staff from health dispensaries. When the ill-defined deaths were further categorised according to their R code (with the R code being a group of ill-defined deaths, with sub-groups), 30.5% (n=320) had unknown cause of death, while 29.3% (n=307) had general symptoms and signs. Almost one fifth of deaths in Kiribati were ill-defined, indicating that the reporting on cause of death can be improved through Medical Certification on Causes of Death training and by other means. Improved cause of death reporting will allow the Ministry of Health and Medical Services to better allocate resources, plan health care service delivery and support the development of evidence based preventative and curative policies.</p>","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"78 3","pages":"103-107"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401198/pdf/hjmph7803_0103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37042357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charmaine Milla, Mary Guo, Ann Chang, Nancy Chen, Jill Miyamura, Tetine Sentell
Childbirth is a national priority area for healthcare quality improvement. Patient perspectives are increasingly valued in healthcare, yet Asian American and Pacific Islander (AAPI) perspectives of healthcare quality are often understudied, particularly from individuals with limited English proficiency (LEP). Our study goal was to understand factors that consumers in Hawai'i, including AAPI and those with LEP, use to compare patient care in hospitals, especially for childbirth. A total of 400 women ages 18 years and older with a recent childbirth completed an in-person interview in English (n=291), Tagalog (n=42), Chinese (n=36), or Marshallese (n=31) on O'ahu, Hawai'i. Participants described if (yes/no), and how (open-ended), they believed hospitals in the state varied in providing patient care. Open-ended responses were coded by two independent raters using the framework approach. Respondents were 53.3% Asian, 30.8% Pacific Islander, 13.5% White, and 2.5% other race/ethnicity; 17.8% reported limited English proficiency. Overall, 66.8% of respondents affirmed that local hospitals varied in patient care; Marshallese, other Pacific Islanders, and non-English speakers were significantly less likely to say that Hawai'i hospitals varied in patient care. Among those who endorsed hospital variation, commonly reported themes about this variation were: (1) patient experience, (2) patient overall impression, (3) childbirth options (eg, waterbirths), (4) staff, (5) facilities (eg, "emergency capabilities"), (6) high-tech levels of care, and (7) the hospital's area of focus (eg, "women and children"). We provide insights into factors that diverse patients use to compare patient care in hospitals in Hawai'i to add value, relevance, and engagement to healthcare quality research and dissemination efforts.
{"title":"Patient Perspectives in Comparing Hospitals for Childbirth: Insights from Hawai'i.","authors":"Charmaine Milla, Mary Guo, Ann Chang, Nancy Chen, Jill Miyamura, Tetine Sentell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Childbirth is a national priority area for healthcare quality improvement. Patient perspectives are increasingly valued in healthcare, yet Asian American and Pacific Islander (AAPI) perspectives of healthcare quality are often understudied, particularly from individuals with limited English proficiency (LEP). Our study goal was to understand factors that consumers in Hawai'i, including AAPI and those with LEP, use to compare patient care in hospitals, especially for childbirth. A total of 400 women ages 18 years and older with a recent childbirth completed an in-person interview in English (n=291), Tagalog (n=42), Chinese (n=36), or Marshallese (n=31) on O'ahu, Hawai'i. Participants described if (yes/no), and how (open-ended), they believed hospitals in the state varied in providing patient care. Open-ended responses were coded by two independent raters using the framework approach. Respondents were 53.3% Asian, 30.8% Pacific Islander, 13.5% White, and 2.5% other race/ethnicity; 17.8% reported limited English proficiency. Overall, 66.8% of respondents affirmed that local hospitals varied in patient care; Marshallese, other Pacific Islanders, and non-English speakers were significantly less likely to say that Hawai'i hospitals varied in patient care. Among those who endorsed hospital variation, commonly reported themes about this variation were: (1) patient experience, (2) patient overall impression, (3) childbirth options (eg, waterbirths), (4) staff, (5) facilities (eg, \"emergency capabilities\"), (6) high-tech levels of care, and (7) the hospital's area of focus (eg, \"women and children\"). We provide insights into factors that diverse patients use to compare patient care in hospitals in Hawai'i to add value, relevance, and engagement to healthcare quality research and dissemination efforts.</p>","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"78 3","pages":"89-97"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401201/pdf/hjmph7803_0089.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37042356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hawai'i Journal Watch: Highlights of recent research from the University of Hawai'i and the Hawai'i State Department of Health.","authors":"Karen Rowan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"78 3","pages":"115"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401202/pdf/hjmph7803_0115.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37041253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
May Vawer, Rick Rutiz, Viliami Tukuafu, Kirsten Whatley, Kauwila Hanchett, Lipoa Kahaleuahi, Lehualani Park, Mikala Minn, Beth Blackburn, Malia Young, Ann Muneno, Deborah A Taira, Tetine Sentell, Todd B Seto
There are substantial and persistent health disparities among Native Hawaiians that are best addressed through multilevel socio-ecological approaches, which are tailored to the needs of the community. Partnerships that link academic investigators with grass roots community members have the potential to profoundly reduce health disparities and improve health and wellness by increasing the capacity of community-based organizations to provide leadership in health advocacy, support community health promotion, and participate in health research. We describe a 14-year partnership to reduce Native Hawaiian health disparities between investigators from The Queen's Medical Center and University of Hawai'i John A. Burns School of Medicine (QMC-JABSOM) and community members in Hana, a geographically isolated, underserved, rural community with the second largest concentration of Native Hawaiians in the state. Our relationship started as an investigator-initiated, National Institutes of Health-sponsored study to explore familial cardiomyopathy, and transitioned to a community-based project that combined community cardiovascular health screening fairs with a qualitative research study to understand attitudes towards genetic research. Most recently, QMC-JABSOM has partnered closely with Ma Ka Hana Ka 'Ike, an award-winning construction skills training program for at-risk youth in Hana, to develop innovative, culturally based interventions to improve health and well-being among Native Hawaiians using principles of community-based participatory research.
夏威夷土著居民之间存在着巨大而持久的健康差距,最好通过针对社区需要的多层次社会生态方法加以解决。将学术调查人员与基层社区成员联系起来的伙伴关系有可能通过提高社区组织在卫生宣传、支持社区卫生促进和参与卫生研究方面发挥领导作用的能力,大大减少卫生差距并改善健康和保健。我们描述了一项为期14年的合作伙伴关系,旨在减少皇后医学中心和夏威夷大学约翰·a·伯恩斯医学院(QMC-JABSOM)的研究人员与哈纳社区成员之间的夏威夷原住民健康差距,哈纳是一个地理上孤立的、服务不足的农村社区,是该州夏威夷原住民的第二大集中地。我们的关系开始于一个研究者发起的,由美国国立卫生研究院赞助的探索家族性心肌病的研究,并转变为一个基于社区的项目,该项目将社区心血管健康筛查博览会与定性研究结合起来,以了解对基因研究的态度。最近,QMC-JABSOM与Ma Ka Hana Ka 'Ike密切合作,Ma Ka Hana Ka 'Ike是一个屡获殊荣的建筑技能培训项目,旨在为Hana的高危青年开发创新的、基于文化的干预措施,利用基于社区的参与性研究原则,改善夏威夷原住民的健康和福祉。
{"title":"Insights in Public Health: <i>Hana Pu No Ke Ola O Hana</i> (\"Working Together for the Health of Hana\"): Our 14-year CBPR Journey.","authors":"May Vawer, Rick Rutiz, Viliami Tukuafu, Kirsten Whatley, Kauwila Hanchett, Lipoa Kahaleuahi, Lehualani Park, Mikala Minn, Beth Blackburn, Malia Young, Ann Muneno, Deborah A Taira, Tetine Sentell, Todd B Seto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There are substantial and persistent health disparities among Native Hawaiians that are best addressed through multilevel socio-ecological approaches, which are tailored to the needs of the community. Partnerships that link academic investigators with grass roots community members have the potential to profoundly reduce health disparities and improve health and wellness by increasing the capacity of community-based organizations to provide leadership in health advocacy, support community health promotion, and participate in health research. We describe a 14-year partnership to reduce Native Hawaiian health disparities between investigators from The Queen's Medical Center and University of Hawai'i John A. Burns School of Medicine (QMC-JABSOM) and community members in Hana, a geographically isolated, underserved, rural community with the second largest concentration of Native Hawaiians in the state. Our relationship started as an investigator-initiated, National Institutes of Health-sponsored study to explore familial cardiomyopathy, and transitioned to a community-based project that combined community cardiovascular health screening fairs with a qualitative research study to understand attitudes towards genetic research. Most recently, QMC-JABSOM has partnered closely with Ma Ka Hana Ka 'Ike, an award-winning construction skills training program for at-risk youth in Hana, to develop innovative, culturally based interventions to improve health and well-being among Native Hawaiians using principles of community-based participatory research.</p>","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"78 3","pages":"111-114"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401196/pdf/hjmph7803_0111.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37041254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breast cancer is a non-communicable disease and a major health problem in the world. Based on the data from WHO in 2012, the incidence of breast cancer is reported as 1.67 million cases. One cause of the highest morbidity and mortality in breast cancer is chemoresistance. Various attempts were made to solve this problem. The purpose of this review is to describe the potential of fucoidan from brown seaweeds (Sargassum sp.) as innovation therapy on breast cancer. Fucoidan as proapoptotic agents affect many target cells (multi-targets) to induce apoptosis. Fucoidan has a potential for a new treatment of breast cancer because of its potent proapoptotic and anti-metastatic properties. However, no research has yet evaluated this in clinical trial. Hence, further studies are needed to confirm the true potential of fucoidan from brown seaweeds as therapy for breast cancer. Keywords: anti-proliferative agents, pro-apoptotic agents, fucoidan, breast cancer
{"title":"Potential of Fucoidan From Brown Seaweeds (Sargassum sp.) as Innovation Therapy on Breast Cancer","authors":"Agung B S Satyarsa","doi":"10.28932/JMH.V2I3.1235","DOIUrl":"https://doi.org/10.28932/JMH.V2I3.1235","url":null,"abstract":"Breast cancer is a non-communicable disease and a major health problem in the world. Based on the data from WHO in 2012, the incidence of breast cancer is reported as 1.67 million cases. One cause of the highest morbidity and mortality in breast cancer is chemoresistance. Various attempts were made to solve this problem. The purpose of this review is to describe the potential of fucoidan from brown seaweeds (Sargassum sp.) as innovation therapy on breast cancer. Fucoidan as proapoptotic agents affect many target cells (multi-targets) to induce apoptosis. Fucoidan has a potential for a new treatment of breast cancer because of its potent proapoptotic and anti-metastatic properties. However, no research has yet evaluated this in clinical trial. Hence, further studies are needed to confirm the true potential of fucoidan from brown seaweeds as therapy for breast cancer. \u0000 \u0000 \u0000Keywords: anti-proliferative agents, pro-apoptotic agents, fucoidan, breast cancer","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75409579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Winny W Nasution, H. Heryaman, J. W. Martha, A. Ridwan
Diabetes mellitus (DM) is a metabolic disease that has a high prevalence in Asia, including Indonesia. One of the complications of DM is Peripheral Artery Disease (PAP). Ankle Brachial Index (ABI) measurement is a simple and non-invasive methods that can be used for PAP evaluation. This study aims to provide an overview of the clinical manifestations of PAP and the value of ABI as early detection of PAP in patients with type-2 DM. This research uses quantitative descriptive design studies. The research variables used to assess PAP were ABI values, age, sex, duration of diabetes mellitus, hypertension, and clinical manifestations of PAP such as pain, intermittent claudication, muscle atrophy, skin discoloration, sweating, wound healing impairment, and gangrene. This study involved 92 research subjects. From the study we found out that the normal ABI value and the ABI value of the PAP category in patients with type 2 diabetes were 91.3% and 7.6%. The ABI value of the PAP category in DM patients is more commonly found in women (6.5%), adult patients (5.4%), duration of DM up to 2 years (5.4%), and with hypertension (5.4%) . Pain and numbness are the most common clinical manifestations of PAP in DM patients. Keywords: diabetes mellitus, ankle brachial index, peripheral artery disease.
{"title":"Clinical Manifestation of Peripheral Artery Disease in Type 2 Diabetes Melitus with Ankle Branchial Index Measurement","authors":"Winny W Nasution, H. Heryaman, J. W. Martha, A. Ridwan","doi":"10.28932/JMH.V2I3.1224","DOIUrl":"https://doi.org/10.28932/JMH.V2I3.1224","url":null,"abstract":"Diabetes mellitus (DM) is a metabolic disease that has a high prevalence in Asia, including Indonesia. One of the complications of DM is Peripheral Artery Disease (PAP). Ankle Brachial Index (ABI) measurement is a simple and non-invasive methods that can be used for PAP evaluation. This study aims to provide an overview of the clinical manifestations of PAP and the value of ABI as early detection of PAP in patients with type-2 DM. This research uses quantitative descriptive design studies. The research variables used to assess PAP were ABI values, age, sex, duration of diabetes mellitus, hypertension, and clinical manifestations of PAP such as pain, intermittent claudication, muscle atrophy, skin discoloration, sweating, wound healing impairment, and gangrene. This study involved 92 research subjects. From the study we found out that the normal ABI value and the ABI value of the PAP category in patients with type 2 diabetes were 91.3% and 7.6%. The ABI value of the PAP category in DM patients is more commonly found in women (6.5%), adult patients (5.4%), duration of DM up to 2 years (5.4%), and with hypertension (5.4%) . Pain and numbness are the most common clinical manifestations of PAP in DM patients. \u0000 \u0000 \u0000Keywords: diabetes mellitus, ankle brachial index, peripheral artery disease.","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86404167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meilinah Hidayat, S. Prahastuti, A. A. Soemardji, Khomaini Hasan, G. Audrey, Janifer Gabriella, Petrisia Luvina, Cicilia Liempapas
The usage of Cisplatin (CP) can cause side effects such as toxicity and impaired kidneyfunction. Poor kidney function causes dyslipidemia and hyperuricemia. Researchers in Canadastate that pea protein hydrolysates can improve kidney function. The aim was to examine thehypolipidemic effect of 8 types of pea protein hydrolysate on lipid profiles and uric acid in CPinduced rats in purpose to find protein sources origin of Indonesia for kidney therapy. This is atrue experimental study using fifty female Wistar rats divided into 10 treatment groups.Weadministered 8 types of pea protein hydrolysate for 30 days. On day 7 all rats (except negativecontrol) were induced CP intraperitoneally. Study parameters was evaluated on days 12 and30. In general, all treatments showed good hypolipidemic effects, and differed significantly fromCP group (p <0.01). The group that showed lowest total cholesterol, LDL and triglycerideresults is yellow pea protein hydrolysate Neutrase; HDL: green peas protein hydrolysatebromelain, uric acid: protein hydrolysate of pea protein isolate bromelain. As conclusion,protein hydrolysates of pea has good hypolipidemic effects on Lipid profile and Uric Acid inCP-induced nephropathy Rats. Keywords: protein hydrolysates, green peas, neutrase, bromelain, lipid profiles
{"title":"Hypolipidemic Effects of Pea Protein Hydrolysates on Lipid Profile and Uric Acid in Cisplatin-Induced Nephropathy Rats","authors":"Meilinah Hidayat, S. Prahastuti, A. A. Soemardji, Khomaini Hasan, G. Audrey, Janifer Gabriella, Petrisia Luvina, Cicilia Liempapas","doi":"10.28932/jmh.v2i3.1234","DOIUrl":"https://doi.org/10.28932/jmh.v2i3.1234","url":null,"abstract":"The usage of Cisplatin (CP) can cause side effects such as toxicity and impaired kidneyfunction. Poor kidney function causes dyslipidemia and hyperuricemia. Researchers in Canadastate that pea protein hydrolysates can improve kidney function. The aim was to examine thehypolipidemic effect of 8 types of pea protein hydrolysate on lipid profiles and uric acid in CPinduced rats in purpose to find protein sources origin of Indonesia for kidney therapy. This is atrue experimental study using fifty female Wistar rats divided into 10 treatment groups.Weadministered 8 types of pea protein hydrolysate for 30 days. On day 7 all rats (except negativecontrol) were induced CP intraperitoneally. Study parameters was evaluated on days 12 and30. In general, all treatments showed good hypolipidemic effects, and differed significantly fromCP group (p <0.01). The group that showed lowest total cholesterol, LDL and triglycerideresults is yellow pea protein hydrolysate Neutrase; HDL: green peas protein hydrolysatebromelain, uric acid: protein hydrolysate of pea protein isolate bromelain. As conclusion,protein hydrolysates of pea has good hypolipidemic effects on Lipid profile and Uric Acid inCP-induced nephropathy Rats. \u0000Keywords: protein hydrolysates, green peas, neutrase, bromelain, lipid profiles","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73253406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Growth in children is very important because it affects a person's height as an adult.Qualified and adequate nutrition play a significant role in growth. Adequate milk consumptioncan affect bone growth which ultimately affects height and helps reduce the risk of bone loss.The purpose of this study was to determine the correlation between milk consumption andheight in children. This study is an analytic observational study, involving 126 subjects aged 6-9 years from an elementary school in Bandung. The sample was taken by whole samplingtechnique. Data collection was carried out using questionnaires and height measurements. Thedata was analyzed using the Gamma correlation test. The statistical results showed a significantrelationship between the frequency of milk consumption and height (p = 0.044) with a mediumcorrelation coefficient (r = 0.430) and a positive correlation direction which meant an increasein the frequency of milk consumption along with the increasing height in children aged 6-9years. We concluded that milk consumption correlates with body height in children.Keywords: milk consumption, body height, children, correlation
{"title":"Milk Consumption Correlates with Body Height in Children","authors":"Evan Tirtasaputra, Grace Puspasari, T. Lucretia","doi":"10.28932/JMH.V2I3.1232","DOIUrl":"https://doi.org/10.28932/JMH.V2I3.1232","url":null,"abstract":"Growth in children is very important because it affects a person's height as an adult.Qualified and adequate nutrition play a significant role in growth. Adequate milk consumptioncan affect bone growth which ultimately affects height and helps reduce the risk of bone loss.The purpose of this study was to determine the correlation between milk consumption andheight in children. This study is an analytic observational study, involving 126 subjects aged 6-9 years from an elementary school in Bandung. The sample was taken by whole samplingtechnique. Data collection was carried out using questionnaires and height measurements. Thedata was analyzed using the Gamma correlation test. The statistical results showed a significantrelationship between the frequency of milk consumption and height (p = 0.044) with a mediumcorrelation coefficient (r = 0.430) and a positive correlation direction which meant an increasein the frequency of milk consumption along with the increasing height in children aged 6-9years. We concluded that milk consumption correlates with body height in children.Keywords: milk consumption, body height, children, correlation","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89752042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberculous meningitis (TBM) is the most common type of meningitis with a highmortality rate (20-41%). There are limited data on factors associated with outcome oftreatment, especially in Indonesia. Fever is a common inflammatory process in meningitispatients. This study aims to investigate the association between fever during admission andoutcome of treatment in TBM patients treated in the In-patient Neurology Department at HasanSadikin Hospital Bandung. This is an observational retrospective cohort study conducted byusing medical records from 2017. The inclusion criteria of this study were all medical recordsof inpatients who were diagnosed as TBM and ?18 years old, while the exclusion criteria wereincomplete medical records. The variables in this study were age, gender, body temperature,classification of TBM, and Glasglow Outcome Scale (GOS). There were 125 medical recordswhich fulfilled the inclusion criteria. Kruskal- Wallis test showed that fever was notsignificantly associated with GOS (p=0.193). In conclusion, fever during admission was notassociated with GOS in TBM patients.Keywords: tuberculous meningitis, fever, Glasglow Outcome Scale, outcome
{"title":"Association between Fever during Admission and Outcome of Treatment in Tuberculous Meningitis Patients in Hasan Sadikin General Hospital Bandung","authors":"Regita A Kuswanto, A. Rizal, R. Koesoemadinata","doi":"10.28932/JMH.V2I3.1233","DOIUrl":"https://doi.org/10.28932/JMH.V2I3.1233","url":null,"abstract":"Tuberculous meningitis (TBM) is the most common type of meningitis with a highmortality rate (20-41%). There are limited data on factors associated with outcome oftreatment, especially in Indonesia. Fever is a common inflammatory process in meningitispatients. This study aims to investigate the association between fever during admission andoutcome of treatment in TBM patients treated in the In-patient Neurology Department at HasanSadikin Hospital Bandung. This is an observational retrospective cohort study conducted byusing medical records from 2017. The inclusion criteria of this study were all medical recordsof inpatients who were diagnosed as TBM and ?18 years old, while the exclusion criteria wereincomplete medical records. The variables in this study were age, gender, body temperature,classification of TBM, and Glasglow Outcome Scale (GOS). There were 125 medical recordswhich fulfilled the inclusion criteria. Kruskal- Wallis test showed that fever was notsignificantly associated with GOS (p=0.193). In conclusion, fever during admission was notassociated with GOS in TBM patients.Keywords: tuberculous meningitis, fever, Glasglow Outcome Scale, outcome","PeriodicalId":73197,"journal":{"name":"Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75168807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}