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The Impact of a 4-Domain Wellness-Initiative Curriculum on Internal Medicine Resident Physicians. 4 领域健康倡议课程对内科住院医生的影响。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1779
Esha Vallabhaneni, Luigi Cubeddu, Ryan Petit, Fernando Poli, Premal Patel, Cynthia Rivera

Background: There is a trend toward fostering well-being, or the state of being happy and healthy, within the medical community. Historically, resident physicians have faced high rates of distress during training. A structured well-being curriculum in residency programs may shift residents' mindsets from survival and resilience to one centered on purpose, engagement, and joy.

Methods: An original well-being curriculum was administered to residents in person at a single institution every 5 weeks for approximately 10 well-being workshops, totaling around 20 hours of curriculum exposure during every academic year. The well-being curriculum was divided into 4 domains: cognitive distortions and problematic mindsets, mindfulness and meditation, creative outlets, and self-compassion.Residents exposed to at least 1 year of the well-being curriculum were asked to answer an anonymous survey. Four questions were asked for each of the 4 domains. The first and second questions asked how familiar they were with the topic before and after the workshops on a scale of 1-5 of familiarity. The third and fourth questions asked how much the knowledge acquired influenced their professional and personal life on a scale of 1-5 of influence.

Results: Before curriculum exposure, the average for moderate or higher levels of knowledge across all domains was 22.7%, which improved to 77.3% after curriculum completion. Overall, 58.6% of participants felt the knowledge of the domains was moderately or extremely influential in their professional lives and 83.6% in their personal lives. There were no significant differences between post-graduate year 2 and post-graduate year 3 residents for any domains examined before and after the wellness workshops.

Conclusion: A 4-domain well-being curriculum practiced in a group setting positively impacted participating residents in their personal and professional lives. Further studies need to be performed on a larger scale to assess if the curriculum fits the needs of the broader medical community.

背景:在医学界,培养幸福感(即快乐和健康的状态)已成为一种趋势。从历史上看,住院医师在培训期间面临的困扰率很高。在住院医师培训项目中开展有组织的幸福感课程,可将住院医师的心态从生存和应变能力转变为以目标、参与和快乐为中心:方法:在一个机构中,每 5 周为住院医师举办约 10 次幸福感讲习班,每学年总计约 20 个小时的课程。幸福感课程分为 4 个领域:认知扭曲和问题心态、正念和冥想、创造性出口和自我同情。针对 4 个领域分别提出了 4 个问题。第一个和第二个问题询问他们在参加工作坊之前和之后对该主题的熟悉程度,熟悉程度分为 1-5 级。第三和第四个问题是关于所学知识对其职业和个人生活的影响程度,以 1-5 分表示:结果:在学习课程之前,学员在所有领域的知识水平达到中等或中等以上的平均比例为 22.7%,而在完成课程之后,这一比例提高到了 77.3%。总体而言,58.6%的学员认为这些领域的知识对他们的职业生活有中等或极大的影响,83.6%的学员认为这些领域的知识对他们的个人生活有中等或极大的影响。毕业后第二年的住院医师和毕业后第三年的住院医师在健康工作坊前后的任何领域都没有明显差异:结论:在小组环境中实施的 4 个领域的健康课程对参与的住院医师的个人和职业生活产生了积极影响。需要进行更大规模的进一步研究,以评估该课程是否符合更广泛的医学界需求。
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引用次数: 0
Well-Being and Leadership Within the Emergency Department. 急诊科内的幸福感与领导力。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1781
Jacob T Berg, Thomas Matese, Dennis Anthony Cardriche, David Hotwagner

Description This article looks at well-being and the role of leadership from the perspective of emergency medicine. The importance of leadership within the emergency department (ED), emergency medicine writing at large, and the prevention of burnout and compassion fatigue cannot be overstated. This article looks at the need for more research and measured interventions within the ED. It also highlights some measures that could be taken to help improve well-being from a leadership perspective to improve patient safety and outcomes within the ED.

说明 本文从急诊医学的角度探讨了幸福感和领导力的作用。领导力在急诊科(ED)、急诊医学写作以及预防职业倦怠和同情疲劳方面的重要性怎么强调都不为过。本文探讨了在急诊科开展更多研究和采取更多干预措施的必要性。文章还强调了一些可采取的措施,这些措施有助于从领导力的角度提高急诊科的福利,从而改善急诊科的患者安全和治疗效果。
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引用次数: 0
What Motivates You? 你的动力是什么?
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1840
Mohamad S Saad

Description For over 100 years, we have tried to understand how human motivation works. Although various theories have been developed and different experiments have been conducted to explain motivational drive, we have realized that extrinsic motivation factors, such as rewards and punishment, and financial incentives are not the answers. More important and central to motivation is nourishing our innate human need to be autonomous, competent, and to relate to our organizational culture. All of us need to understand the story of motivation because, as dire as our need for high-quality motivation is, high-quality motivation remains an asymptote.

100 多年来,我们一直试图了解人类的动机是如何产生的。尽管人们提出了各种理论,并进行了不同的实验来解释动机驱动力,但我们已经意识到,奖惩和经济激励等外在激励因素并不是答案。更重要的是,激励的核心是滋养我们人类与生俱来的自主、胜任以及与组织文化相联系的需求。我们所有人都需要了解激励的故事,因为尽管我们迫切需要高质量的激励,但高质量的激励仍然是一个渐近线。
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引用次数: 0
A Multi-Wave Study of Factors Associated With Resident Engagement, Depression, Burnout, and Stay Intent. 关于住院医师参与度、抑郁、倦怠和住院意向相关因素的多波研究。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1837
Anne M Brafford, Brendon Ellis, Greg Guldner, Gabrielle Riazi, Xitao Liu, Jessica C Wells, Jason T Siegel

Background: Many studies have documented the epidemic of mental ill-being among resident physicians, but fewer have focused on mental well-being or on guiding intervention design to make progress toward positive change in residency programs to support resident thriving. Informed by the job demands-resources model (JD-R) and positive psychology, the current study examines 4 potential predictors of residents' ill-being (burnout, depression) and well-being (engagement, stay intent) that are malleable and thus capable of change through intervention: psychological capital (PsyCap), supervising physicians' autonomy-supportive leadership style (ASL), social support, and meaningful work.

Methods: Three waves of data were collected between November 2017 and September 2018 at a large hospital system in the United States. Due to participant response rates, we were unable to conduct a planned longitudinal analysis. Therefore, for each wave, Bayesian regression analyses were used to examine cross-sectional relationships between the 4 predictors and each outcome.

Results: Although findings varied across the study's 3 waves, the outcomes were largely as expected. With only 1 exception (depressive symptoms in Wave 2), meaningful work significantly predicted all outcome variables in the expected direction across all 3 waves. PsyCap significantly predicted burnout, depressive symptoms, and engagement in the expected direction across all 3 waves. ASL significantly predicted engagement in the expected direction across all 3 waves, as well as depressive symptoms and stay intent in 2 waves, and burnout in 1 wave. Social support significantly negatively predicted depressive symptoms in all 3 waves and burnout in 1 wave.

Conclusion: Applying the JD-R framework and a positive psychology lens can open new pathways for developing programming to support resident thriving. Meaningful work, PsyCap, ASL, and social support all significantly predicted 1 or more outcomes related to resident thriving (burnout, depression, engagement, stay intent) across all 3 waves. Thus, this study provides theoretical and practical implications for future intervention studies and designing current programming for resident thriving.

背景:许多研究都记录了住院医师精神疾病的流行情况,但很少有研究关注住院医师的精神健康或指导干预措施的设计,以促进住院医师培训项目的积极变革,支持住院医师的茁壮成长。在工作需求-资源模型(JD-R)和积极心理学的启发下,本研究探讨了住院医师不良情绪(职业倦怠、抑郁)和幸福感(参与度、住院意向)的四个潜在预测因素,这些因素具有可塑性,因此可以通过干预措施加以改变:心理资本(PsyCap)、指导医师的自主-支持型领导风格(ASL)、社会支持和有意义的工作:2017年11月至2018年9月期间,我们在美国一家大型医院系统收集了三波数据。由于参与者的回复率问题,我们无法按计划进行纵向分析。因此,在每一波数据中,我们都使用贝叶斯回归分析来检验 4 个预测因子与每个结果之间的横截面关系:尽管研究结果在 3 个波次中有所不同,但结果基本符合预期。只有一个例外(第 2 波中的抑郁症状),在所有 3 波中,有意义的工作都能以预期的方向显著预测所有结果变量。在所有 3 个波次中,PsyCap 对职业倦怠、抑郁症状和敬业度的预测都与预期方向一致。ASL 对所有 3 个波次的参与度都有明显的预期预测作用,对 2 个波次的抑郁症状和逗留意愿以及 1 个波次的职业倦怠也有明显的预期作用。社会支持对所有 3 个波次的抑郁症状和 1 个波次的职业倦怠有明显的负向预测作用:结论:应用 JD-R 框架和积极心理学视角可以为制定支持住院医师茁壮成长的计划开辟新的途径。在所有 3 个波次中,有意义的工作、PsyCap、ASL 和社会支持都能显著预测一种或多种与住院医师蓬勃发展相关的结果(职业倦怠、抑郁、参与度、住院意愿)。因此,本研究为未来的干预研究和设计当前的住院医师蓬勃发展计划提供了理论和实践意义。
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引用次数: 0
Creating and Supporting Well-Being in Graduate Medical Education. 在医学研究生教育中创造和支持幸福。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1984
Gregory Guldner

Description Graduate medical education strives to create the next generation of skillful and compassionate physicians for our nation. Yet, research shows a high degree of depression, anxiety, workplace burnout, lack of engagement, and general dissatisfaction with the work and learning environment for many of these dedicated individuals. We present this special issue related to creating and supporting well-being in the graduate medical education community.

描述 医学研究生教育致力于为我国培养技术精湛、富有同情心的下一代医生。然而,研究表明,这些兢兢业业的人中有很多人存在抑郁、焦虑、工作倦怠、缺乏参与感以及对工作和学习环境的普遍不满。我们特此推出本期特刊,探讨如何在医学研究生教育界创造和支持幸福感。
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引用次数: 0
Turmoil. 动荡。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1912
Derek Kent

Description I painted this picture after tearing up over the phone with her parents. "I think she's passing away," I had told them, "You'd better come up to the hospital." Inexperienced as a brand new physician, I felt like I was drowning in my responsibility over the care of my patients. Real people, with real lives, with real consequences to my decisions. It has gotten easier to feel okay while helping other humans pass away. And it sounds a little dramatic, but I've found ways to help myself cope without being stranded by the waves.

描述 我是在和她父母通完电话后泪流满面地画了这幅画。"我对他们说:"我想她快不行了,你们最好到医院来一趟。作为一名经验不足的新医生,我感觉自己被照顾病人的责任淹没了。真实的人,真实的生活,我的决定会带来真实的后果。在帮助其他人离开人世的时候,我越来越容易感觉自己没事了。这听起来有点夸张,但我已经找到了一些方法来帮助自己应对,而不至于被海浪搁浅。
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引用次数: 0
Burnout in Graduate Medical Education: Uncovering Resident Burnout Profiles Using Cluster Analysis. 医学研究生教育中的职业倦怠:利用聚类分析揭示住院医师倦怠特征。
Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1784
Nicholas A Yaghmour, Nastassia M Savage, Paul H Rockey, Sally A Santen, Kristen E DeCarlo, Grace Hickam, Joanne G Schwartzberg, DeWitt C Baldwin, Robert A Perera

Background: Burnout is common among residents and negatively impacts patient care and professional development. Residents vary in terms of their experience of burnout. Our objective was to employ cluster analysis, a statistical method of separating participants into discrete groups based on response patterns, to uncover resident burnout profiles using the exhaustion and engagement sub-scales of the Oldenburg Burnout Inventory (OLBI) in a cross-sectional, multispecialty survey of United States medical residents.

Methods: The 2017 ACGME resident survey provided residents with an optional, anonymous addendum containing 3 engagement and 3 exhaustion items from the OBLI, a 2-item depression screen (PHQ-2), general queries about health and satisfaction, and whether respondents would still choose medicine as a career. Gaussian finite mixture models were fit to exhaustion and disengagement scores, with the resultant clusters compared across PHQ-2 depression screen results. Other variables were used to demonstrate evidence for the validity and utility of this approach.

Results: From 14 088 responses, 4 clusters were identified as statistically and theoretically distinct: Highly Engaged (25.8% of respondents), Engaged (55.2%), Disengaged (9.4%), and Highly Exhausted (9.5%). Only 2% of Highly Engaged respondents screened positive for depression, compared with 8% of Engaged respondents, 29% of Disengaged respondents, and 53% of Highly Exhausted respondents. Similar patterns emerged for the general query about health, satisfaction, and whether respondents would choose medicine as a career again.

Conclusion: Clustering based on exhaustion and disengagement scores differentiated residents into 4 meaningful groups. Interventions that mitigate resident burnout should account for differences among clusters.

背景:职业倦怠在住院医师中很常见,会对患者护理和专业发展造成负面影响。住院医师对职业倦怠的体验各不相同。我们的目标是采用聚类分析(一种根据反应模式将参与者分为不同组别的统计方法),在对美国医学住院医师进行的一项横向、多专科调查中,使用奥登堡倦怠量表(OLBI)中的 "精疲力竭 "和 "投入 "两个分量表来揭示住院医师的倦怠特征:2017 年 ACGME 住院医师调查为住院医师提供了一个可选的匿名附录,其中包含奥登堡倦怠量表中的 3 个参与和 3 个枯竭项目、2 个抑郁筛查项目(PHQ-2)、有关健康和满意度的一般询问以及受访者是否仍将选择医学作为职业。高斯有限混合模型适用于疲惫和脱离得分,并将得出的聚类结果与 PHQ-2 抑郁症筛查结果进行比较。还使用了其他变量来证明这种方法的有效性和实用性:结果:从 14 088 份回复中,确定了 4 个在统计和理论上截然不同的群组:高度投入(占回复者的 25.8%)、投入(占回复者的 55.2%)、脱离(占回复者的 9.4%)和高度疲惫(占回复者的 9.5%)。只有 2% 的 "高度投入 "受访者的抑郁症筛查呈阳性,而 "投入 "受访者为 8%,"脱离 "受访者为 29%,"高度疲惫 "受访者为 53%。在有关健康、满意度以及受访者是否会再次选择医学作为职业的一般性询问中,也出现了类似的模式:结论:根据疲惫和脱离得分进行的分组将住院医师分为 4 个有意义的组别。减轻住院医师职业倦怠的干预措施应考虑到不同组别之间的差异。
{"title":"Burnout in Graduate Medical Education: Uncovering Resident Burnout Profiles Using Cluster Analysis.","authors":"Nicholas A Yaghmour, Nastassia M Savage, Paul H Rockey, Sally A Santen, Kristen E DeCarlo, Grace Hickam, Joanne G Schwartzberg, DeWitt C Baldwin, Robert A Perera","doi":"10.36518/2689-0216.1784","DOIUrl":"10.36518/2689-0216.1784","url":null,"abstract":"<p><strong>Background: </strong>Burnout is common among residents and negatively impacts patient care and professional development. Residents vary in terms of their experience of burnout. Our objective was to employ cluster analysis, a statistical method of separating participants into discrete groups based on response patterns, to uncover resident burnout profiles using the exhaustion and engagement sub-scales of the Oldenburg Burnout Inventory (OLBI) in a cross-sectional, multispecialty survey of United States medical residents.</p><p><strong>Methods: </strong>The 2017 ACGME resident survey provided residents with an optional, anonymous addendum containing 3 engagement and 3 exhaustion items from the OBLI, a 2-item depression screen (PHQ-2), general queries about health and satisfaction, and whether respondents would still choose medicine as a career. Gaussian finite mixture models were fit to exhaustion and disengagement scores, with the resultant clusters compared across PHQ-2 depression screen results. Other variables were used to demonstrate evidence for the validity and utility of this approach.</p><p><strong>Results: </strong>From 14 088 responses, 4 clusters were identified as statistically and theoretically distinct: Highly Engaged (25.8% of respondents), Engaged (55.2%), Disengaged (9.4%), and Highly Exhausted (9.5%). Only 2% of Highly Engaged respondents screened positive for depression, compared with 8% of Engaged respondents, 29% of Disengaged respondents, and 53% of Highly Exhausted respondents. Similar patterns emerged for the general query about health, satisfaction, and whether respondents would choose medicine as a career again.</p><p><strong>Conclusion: </strong>Clustering based on exhaustion and disengagement scores differentiated residents into 4 meaningful groups. Interventions that mitigate resident burnout should account for differences among clusters.</p>","PeriodicalId":73198,"journal":{"name":"HCA healthcare journal of medicine","volume":"5 3","pages":"237-250"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drivers of Being Unhoused and the Prevalence of Health Conditions among Unhoused Individuals in Asheville, NC. 北卡罗来纳州阿什维尔市无人居住的驱动因素和无人居住者健康状况的普遍性。
Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1594
Andrea K Yontz, Amber Beane, Tessa Frank, Amy Upham, Dustin V Patil, Dan Pizzo, Steve Buie, Jacqueline R Halladay

Background: During the COVID-19 pandemic, there was an increase in the number of unhoused individuals in Asheville, North Carolina resulting in more tent encampments.Understanding the physical, mental, and socially determined health characteristics associated with being unhoused can help guide stakeholders with policy development, healthcare program planning, and funding decisions to support unhoused individuals.

Methods: In this study, we used an observational cross-section methodology. Using a convenience sample approach, we interviewed 101 participants who were receiving services from 2 emergency hotel shelters, a day center, and a resource center. Data were analyzed using descriptive statistics, and open-ended responses were collected and grouped to provide context.

Results: Most participants were White (71%) and identified as male (76%). Over 60% reported having a high school education or advanced degree. Of the participants, 76% reported being unhoused for more than 6 months, and their last permanent housing was in Western North Carolina. Dental disease, chronic pain, and hypertension were common physical conditions. PTSD, depression, and anxiety were common mental health conditions. A lack of transportation was the most noted socially determined challenge. Marijuana, methamphetamine, and alcohol were the most often used substances, where methamphetamine was noted to be particularly problematic for the participants.

Conclusion: Understanding the physical, mental, and social issues of the complex unhoused population can assist policymakers, healthcare providers, and other stakeholders in addressing challenges and testing improvement strategies.

背景:在 COVID-19 大流行期间,北卡罗来纳州阿什维尔市无家可归者的人数增加,导致帐篷营地增多。了解与无家可归者相关的身体、精神和社会健康特征有助于指导利益相关者制定政策、规划医疗保健项目和决定资金来源,以支持无家可归者:在这项研究中,我们采用了观察性横截面方法。采用方便抽样的方法,我们采访了 101 名参与者,他们分别在两家紧急旅馆庇护所、一家日间中心和一家资源中心接受服务。我们使用描述性统计对数据进行了分析,并收集了开放式回答,将其分组以提供背景情况:大多数参与者为白人(71%),男性(76%)。超过 60% 的参与者表示拥有高中或高等学历。在参与者中,有 76% 的人表示无房居住的时间超过 6 个月,他们最后一次获得永久住房是在北卡罗来纳州西部。牙病、慢性疼痛和高血压是常见的身体状况。创伤后应激障碍、抑郁和焦虑是常见的心理健康问题。交通不便是他们面临的最大社会挑战。大麻、甲基苯丙胺和酒精是最常使用的物质,其中甲基苯丙胺对参与者的影响尤为严重:了解复杂的无住房人群的身体、精神和社会问题,有助于政策制定者、医疗服务提供者和其他利益相关者应对挑战并测试改进策略。
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引用次数: 0
Opioid-Related Emergency Department Visits Before and During COVID-19: Association with Community-Level Factors. COVID-19 之前和期间阿片类药物相关的急诊就诊情况:与社区因素的关系
Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1608
Timothy F Page, Weiwei Chen, François Sainfort, Julie A Jacko

Background: The purpose of the study was to investigate the relationship between community-level variables and emergency department (ED) visit rates before and during COVID-19. The focus was on opioid-related ED visits. Despite large declines in overall ED visits during COVID-19, opioid-related visits increased. While visits for avoidable conditions decreased, the opposite was true for opioid-related visits.

Methods: We combined data from Florida EDs with community-level variables from the 2020 American Community Survey. The outcome measures of the study were quarterly ZIP code tabulation-area-level ED visit rates for opioid-related ED visits as well as visit rates for all other causes. Associations with opioid-related visit rates were estimated before and during COVID-19.

Results: The associations between community-level variables and opioid-related visit rates did not match those found when analyzing overall ED visit rates. The increase in opioid-related visits during COVID-19 was not unique to or more prevalent in areas with a larger percentage of racial/ethnic minority populations. However, socioeconomic status was important, as areas with higher unemployment, lower income, lower home ownership, and higher uninsured had higher overall ED visit rates and opioid visit rates during the pandemic. In addition, the negative association with income increased during the pandemic.

Conclusion: These results suggest socioeconomic status should be the focus of prevention and treatment efforts to reduce opioid-related visits in future pandemics. Healthcare organizations can use these results to target their prevention and treatment efforts during future pandemics.

研究背景本研究旨在调查 COVID-19 之前和期间社区变量与急诊室就诊率之间的关系。研究重点是与阿片类药物相关的急诊就诊率。尽管在 COVID-19 期间,急诊室就诊总人数大幅下降,但与阿片类药物相关的就诊人数却有所增加。虽然可避免病症的就诊率有所下降,但与阿片类药物相关的就诊率却相反:我们将佛罗里达州急诊室的数据与 2020 年美国社区调查的社区变量相结合。研究结果的衡量标准是每季度的邮政编码表地区级急诊室阿片类药物相关就诊率以及所有其他原因的就诊率。在 COVID-19 之前和期间,对阿片类药物相关就诊率的相关性进行了估计:结果:社区层面变量与阿片类药物相关就诊率之间的关联与分析总体急诊室就诊率时发现的关联并不一致。在 COVID-19 期间,阿片类药物相关就诊率的增加并不是种族/少数民族人口比例较高的地区独有的现象,也不是这些地区更普遍的现象。然而,社会经济地位也很重要,因为失业率较高、收入较低、住房拥有率较低和无保险率较高的地区在大流行期间的总体急诊室就诊率和阿片类药物就诊率都较高。此外,在大流行期间,与收入的负相关增加:这些结果表明,在未来的大流行中,社会经济状况应成为预防和治疗工作的重点,以减少阿片类药物相关就诊率。医疗机构可以利用这些结果,在未来大流行期间有针对性地开展预防和治疗工作。
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引用次数: 0
Suspected Thiamine Deficiency Secondary to Chronic Gastrointestinal Illness: A Case Report. 继发于慢性胃肠道疾病的疑似硫胺素缺乏症:病例报告。
Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.36518/2689-0216.1649
Abigail L Meckley, Natalie LaGattuta, Elise Gonzalez, Chamonix Kinimaka, Jessica El-Bahri

Introduction: Thiamine deficiency, also known as beriberi, is a nutritional disorder caused by a lack of thiamine (vitamin B1) in the diet. It can occur in 2 forms: dry beriberi, which affects the nervous system, and wet beriberi, which affects the cardiovascular system. Gastrointestinal beriberi is a subtype that affects the digestive system and can lead to multisystem involvement. In the United States (US), thiamine deficiency often arises from chronic malnutrition secondary to alcoholism, known as Wernicke-Korsakoff Syndrome.

Case presentation: A 45-year-old female with no known past medical history or alcohol use disorder came to the emergency department with an altered mental status and with a history of intractable nausea and vomiting for several months prior to presentation. During intake, the medical team discovered she had bilateral lower extremity weakness and an anion gap metabolic acidosis. Her inpatient workup ruled out meningitis, encephalitis, peritonitis, diabetic ketoacidosis, and cerebrovascular accident. A thiamine deficiency was the most probable cause of her presentation, secondary to her protracted history of vomiting and poor oral medication intake. Refeeding syndrome complicated her hospitalization. After replenishing thiamine, the patient experienced significant improvement in mental status and lower extremity weakness. The healthcare team later discharged her with home physical therapy rehabilitation and nutritional counseling.

Conclusion: Thiamine deficiency is not common in the US. However, this case highlights the importance of including this deficiency in the differential when a patient arrives with a history of malnourishment secondary to a gastrointestinal illness with signs of altered mental status and neurological symptoms.

简介硫胺素缺乏症又称脚气病,是一种因饮食中缺乏硫胺素(维生素 B1)而引起的营养失调症。它可分为两种形式:影响神经系统的干性脚气病和影响心血管系统的湿性脚气病。胃肠型脚气病是影响消化系统的一种亚型,可导致多系统受累。在美国,硫胺素缺乏症通常是由酗酒导致的慢性营养不良引起的,被称为 Wernicke-Korsakoff 综合征:一名 45 岁的女性因精神状态改变来到急诊科就诊,她既无既往病史,也无酗酒史。入院时,医疗小组发现她双下肢无力,并伴有阴离子间隙性代谢性酸中毒。住院检查排除了脑膜炎、脑炎、腹膜炎、糖尿病酮症酸中毒和脑血管意外的可能性。由于她有长期呕吐史,而且口服药物摄入不足,因此最有可能的原因是缺乏硫胺素。反食综合征使她的住院治疗变得更加复杂。补充硫胺素后,患者的精神状态和下肢乏力明显好转。随后,医疗团队为她提供了家庭物理治疗康复和营养咨询,让她顺利出院:结论:硫胺素缺乏症在美国并不常见。结论:硫胺素缺乏症在美国并不常见,但本病例强调,当患者因胃肠道疾病继发营养不良,并伴有精神状态改变和神经系统症状时,将硫胺素缺乏症纳入鉴别诊断非常重要。
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引用次数: 0
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