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Immuno-oncology technology最新文献

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91P Identification of T cell receptors from tumour-infiltrating lymphocytes cross-reactive to multiple patient-derived metastatic melanoma cell lines using CRISPR-cas9 mediated TCR replacement 使用CRISPR-cas9介导的TCR替代鉴定肿瘤浸润淋巴细胞对多种患者源性转移性黑色素瘤细胞系交叉反应的T细胞受体
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101176
M.D.D. Crowther , M.C.W. Westergaard , L. Schuster , K.H. Johansen , S.A. Tvingsholm , S. Reker Hadrup , I.M. Svane , Ö. Met
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引用次数: 0
6P Natural IgM and dyslipidemia enhance the efficacy of tumor necrosis factor and interleukin-2 encoding oncolytic adenovirus in solid tumors 6P天然IgM和血脂异常可增强肿瘤坏死因子和编码溶瘤腺病毒的白介素-2在实体瘤中的作用
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101091
J.H.A. Clubb , S.A. Pakola , S. Joenväärä , T. Kudling , T. Tohmola , L. Haybout , V. Arias Illana , E. Jirovec , M. van der Heijden , D.C.A. Quixabeira , T.V. Alanko , K. Jalkanen , M.J. Chisamore , C. Kistler , S. Sorsa , V. Cervera-Carrascon , R. Renkonen , A. Hemminki
{"title":"6P Natural IgM and dyslipidemia enhance the efficacy of tumor necrosis factor and interleukin-2 encoding oncolytic adenovirus in solid tumors","authors":"J.H.A. Clubb , S.A. Pakola , S. Joenväärä , T. Kudling , T. Tohmola , L. Haybout , V. Arias Illana , E. Jirovec , M. van der Heijden , D.C.A. Quixabeira , T.V. Alanko , K. Jalkanen , M.J. Chisamore , C. Kistler , S. Sorsa , V. Cervera-Carrascon , R. Renkonen , A. Hemminki","doi":"10.1016/j.iotech.2025.101091","DOIUrl":"10.1016/j.iotech.2025.101091","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101091"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
76eTiP Prospective evaluation of HERV-K expression and antibody responses in ICI therapy: A biomarker study in NSCLC and HNSCC 在ICI治疗中HERV-K表达和抗体反应的前瞻性评估：一项NSCLC和HNSCC的生物标志物研究
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101159
M.D. Müller , J. Friborg , M. Pohl , P.J. Holst , T.B.B. Gaziel
{"title":"76eTiP Prospective evaluation of HERV-K expression and antibody responses in ICI therapy: A biomarker study in NSCLC and HNSCC","authors":"M.D. Müller , J. Friborg , M. Pohl , P.J. Holst , T.B.B. Gaziel","doi":"10.1016/j.iotech.2025.101159","DOIUrl":"10.1016/j.iotech.2025.101159","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101159"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
67eP A two-gene signature based on HOXA5 and CEACAM16 predicts survival in IDH-Mutant glioma 基于HOXA5和CEACAM16的双基因标记预测idh突变胶质瘤的生存
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101150
M.A. Al-Asadi , H. Khudhur , M.K. Hashki , M.B. Ghanameh , E. Noch
{"title":"67eP A two-gene signature based on HOXA5 and CEACAM16 predicts survival in IDH-Mutant glioma","authors":"M.A. Al-Asadi , H. Khudhur , M.K. Hashki , M.B. Ghanameh , E. Noch","doi":"10.1016/j.iotech.2025.101150","DOIUrl":"10.1016/j.iotech.2025.101150","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101150"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
35P Integrative transcriptomic profiling of tumor antigens and immune genes in ovarian cancer for rational ADC and CPI combinations 卵巢癌肿瘤抗原和免疫基因的35P整合转录组学分析用于合理的ADC和CPI组合
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101118
B.G. Diez, M. García Gómez, M. Amann Arévalo, I. Moreno, C. Gomez Raposo, P. Pérez Segura, J. Bartolomé Arcilla
{"title":"35P Integrative transcriptomic profiling of tumor antigens and immune genes in ovarian cancer for rational ADC and CPI combinations","authors":"B.G. Diez, M. García Gómez, M. Amann Arévalo, I. Moreno, C. Gomez Raposo, P. Pérez Segura, J. Bartolomé Arcilla","doi":"10.1016/j.iotech.2025.101118","DOIUrl":"10.1016/j.iotech.2025.101118","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101118"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
52P Sex-specific biomarkers for prediction of immune checkpoint inhibitor efficacy for advanced melanoma using routine blood tests 52P性别特异性生物标志物用于预测免疫检查点抑制剂对晚期黑色素瘤的疗效，使用常规血液检查
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101135
C. Liu , S. Wickström , H. Helgadottir , S. Egyhazi Brage
{"title":"52P Sex-specific biomarkers for prediction of immune checkpoint inhibitor efficacy for advanced melanoma using routine blood tests","authors":"C. Liu , S. Wickström , H. Helgadottir , S. Egyhazi Brage","doi":"10.1016/j.iotech.2025.101135","DOIUrl":"10.1016/j.iotech.2025.101135","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101135"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
61P Mapping immune evasion in breast cancer: Subtype-specific signatures that predict survival and ICI benefit 61P在乳腺癌中映射免疫逃避：预测生存和ICI获益的亚型特异性特征
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101144
O. Menyhart, B. Gyorffy
{"title":"61P Mapping immune evasion in breast cancer: Subtype-specific signatures that predict survival and ICI benefit","authors":"O. Menyhart, B. Gyorffy","doi":"10.1016/j.iotech.2025.101144","DOIUrl":"10.1016/j.iotech.2025.101144","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101144"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
12P Stromal CD73 expression in early-stage high-risk luminal B-like breast cancer: An exploratory analysis from the randomized Neo-CheckRay trial 12P基质CD73在早期高危腔内b样乳腺癌中的表达：来自Neo-CheckRay随机试验的探索性分析
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101097
Z. Denis , A. De Caluwe , E. Romano , J. Stagg , T. Yin , J. Dhont , F. Lifrange , M. Carausu , C. Sotiriou , L. Buisseret , X. Catteau
{"title":"12P Stromal CD73 expression in early-stage high-risk luminal B-like breast cancer: An exploratory analysis from the randomized Neo-CheckRay trial","authors":"Z. Denis , A. De Caluwe , E. Romano , J. Stagg , T. Yin , J. Dhont , F. Lifrange , M. Carausu , C. Sotiriou , L. Buisseret , X. Catteau","doi":"10.1016/j.iotech.2025.101097","DOIUrl":"10.1016/j.iotech.2025.101097","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101097"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
80P A phase I trial of optimized autologous tumor-infiltrating lymphocyte therapy without exogenous IL-2 in patients with advanced non-small cell lung cancer 无外源性IL-2的优化自体肿瘤浸润淋巴细胞治疗晚期非小细胞肺癌的I期临床试验
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101165
J. Li , X. Chen , J. Ma , Q. Xu , X. Guo , Y. Zhou , W. Li , W. Zhuang , H. Jin , J. Xu
{"title":"80P A phase I trial of optimized autologous tumor-infiltrating lymphocyte therapy without exogenous IL-2 in patients with advanced non-small cell lung cancer","authors":"J. Li , X. Chen , J. Ma , Q. Xu , X. Guo , Y. Zhou , W. Li , W. Zhuang , H. Jin , J. Xu","doi":"10.1016/j.iotech.2025.101165","DOIUrl":"10.1016/j.iotech.2025.101165","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101165"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
99P The impact of peripheral blood effector immune cell reconstitution and allograft T cell composition on survival in patients with myelofibrosis treated with allogeneic hematopoietic stem cell transplantation 外周血效应免疫细胞重构和同种异体移植物T细胞组成对同种异体造血干细胞移植治疗骨髓纤维化患者存活的影响
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101184
M.O. Holmström , L. Minculescu , K. Nørgaard , H.J. Hartling , B. Kornblit , I. Schjødt , M.H. Andersen , N.S. Andersen , H. Sengeløv , A. Hauge , S.L. Petersen , M.K. Andersen , L.S. Friis
{"title":"99P The impact of peripheral blood effector immune cell reconstitution and allograft T cell composition on survival in patients with myelofibrosis treated with allogeneic hematopoietic stem cell transplantation","authors":"M.O. Holmström , L. Minculescu , K. Nørgaard , H.J. Hartling , B. Kornblit , I. Schjødt , M.H. Andersen , N.S. Andersen , H. Sengeløv , A. Hauge , S.L. Petersen , M.K. Andersen , L.S. Friis","doi":"10.1016/j.iotech.2025.101184","DOIUrl":"10.1016/j.iotech.2025.101184","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101184"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145837260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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