Pub Date : 2025-03-01Epub Date: 2025-02-21DOI: 10.1007/s00108-025-01853-0
Michael Lichtenberg, Houman Jalaie
Chronic venous obstructions frequently lead to a substantial reduction in the quality of life of affected patients and as a result to a burden on the healthcare system. Endovascular recanalization and stent implantation of iliofemoral venous obstructions are successful minimally invasive approaches; however, there are still open questions with respect to patient selection, technical procedures and long-term results. This review article summarizes the current state of knowledge on the interventional treatment of postthrombotic syndrome (PTS), particularly on the development of endovascular procedures and stent implantation. Criteria for the patient selection, details of the procedure and the characteristics of special venous stents are discussed.
{"title":"[Endovascular treatment of chronic pelvic vein obstruction].","authors":"Michael Lichtenberg, Houman Jalaie","doi":"10.1007/s00108-025-01853-0","DOIUrl":"10.1007/s00108-025-01853-0","url":null,"abstract":"<p><p>Chronic venous obstructions frequently lead to a substantial reduction in the quality of life of affected patients and as a result to a burden on the healthcare system. Endovascular recanalization and stent implantation of iliofemoral venous obstructions are successful minimally invasive approaches; however, there are still open questions with respect to patient selection, technical procedures and long-term results. This review article summarizes the current state of knowledge on the interventional treatment of postthrombotic syndrome (PTS), particularly on the development of endovascular procedures and stent implantation. Criteria for the patient selection, details of the procedure and the characteristics of special venous stents are discussed.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"283-289"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2025-02-28DOI: 10.1007/s00108-025-01873-w
Ralf Langhoff
The treatment of patients with stenosis of the internal carotid artery (ICA) is based on established guidelines, which includes both surgical and endovascular treatment options; however, the most recent advances, including the emergence of new endovascular treatment methods and techniques, combined with more recent clinical results, throw a new light on the optimal selection and treatment of patients in the current practice. This article deals with the most recent advances in the field of stenting of the extracranial internal carotid artery.
{"title":"[Stenting of the extracranial internal carotid artery].","authors":"Ralf Langhoff","doi":"10.1007/s00108-025-01873-w","DOIUrl":"10.1007/s00108-025-01873-w","url":null,"abstract":"<p><p>The treatment of patients with stenosis of the internal carotid artery (ICA) is based on established guidelines, which includes both surgical and endovascular treatment options; however, the most recent advances, including the emergence of new endovascular treatment methods and techniques, combined with more recent clinical results, throw a new light on the optimal selection and treatment of patients in the current practice. This article deals with the most recent advances in the field of stenting of the extracranial internal carotid artery.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"274-282"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2024-10-01DOI: 10.1007/s00108-024-01801-4
Laura Distelmaier, Christian Gebhard, Antje Holzäpfel, Michael von Bergwelt-Baildon, Sebastian Theurich, Holger Cario, Karsten Spiekermann
The case of a 33-year-old male with recurrent icterus and hemolysis since childhood that was long mistaken for Gilbert disease is presented. Subsequently, the patient also developed splenomegaly and gallstones together with iron overload. Genetic testing revealed the diagnosis of hereditary xerocytosis, which is an erythrocyte membrane disorder causing recurrent hemolysis. Xerocytosis is often challenging to diagnose and the frequency of the condition might be underestimated as there are often no typical findings in the microscopic differential blood count, and Eosin-5-maleimide dye (EMA) test, which is used to diagnose other erythrocyte membrane disorders, is normal. In cases of splenomegaly, iron overload and recurrent hemolysis, or in the case of a clinical diagnosis of Gilbert disease together with one of the above-mentioned symptoms, further investigations and possibly also genetic testing should be considered.
{"title":"[Recurrent hemolysis and iron overload of unclear origin].","authors":"Laura Distelmaier, Christian Gebhard, Antje Holzäpfel, Michael von Bergwelt-Baildon, Sebastian Theurich, Holger Cario, Karsten Spiekermann","doi":"10.1007/s00108-024-01801-4","DOIUrl":"10.1007/s00108-024-01801-4","url":null,"abstract":"<p><p>The case of a 33-year-old male with recurrent icterus and hemolysis since childhood that was long mistaken for Gilbert disease is presented. Subsequently, the patient also developed splenomegaly and gallstones together with iron overload. Genetic testing revealed the diagnosis of hereditary xerocytosis, which is an erythrocyte membrane disorder causing recurrent hemolysis. Xerocytosis is often challenging to diagnose and the frequency of the condition might be underestimated as there are often no typical findings in the microscopic differential blood count, and Eosin-5-maleimide dye (EMA) test, which is used to diagnose other erythrocyte membrane disorders, is normal. In cases of splenomegaly, iron overload and recurrent hemolysis, or in the case of a clinical diagnosis of Gilbert disease together with one of the above-mentioned symptoms, further investigations and possibly also genetic testing should be considered.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"328-330"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-26DOI: 10.1007/s00108-025-01870-z
K R Herrlinger, E F Stange
{"title":"[Erratum to: New treatment targets for inflammatory bowel disease?]","authors":"K R Herrlinger, E F Stange","doi":"10.1007/s00108-025-01870-z","DOIUrl":"https://doi.org/10.1007/s00108-025-01870-z","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-19DOI: 10.1007/s00108-025-01863-y
Hatti Seidl, Lena Thormählen, Marie Pollak, Thula Walter-Rittel, Robert Hättasch, Gerhard Hindricks
A 69-year-old female patient with known recurrence of esophageal cancer presented with fever and elevated inflammatory markers. In the recent past, a suspicious mediastinal lymph node had been biopsied via bronchoscopy. Consequently, a lymph node abscess developed, leading to blood stream infection (pathogen: Streptococcus anginosus) via a fistula into the superior vena cava. Through a preexisting atrial septal defect, the infection also spread to the brain, causing multiple brain abscesses.
{"title":"[An abscess gone astray].","authors":"Hatti Seidl, Lena Thormählen, Marie Pollak, Thula Walter-Rittel, Robert Hättasch, Gerhard Hindricks","doi":"10.1007/s00108-025-01863-y","DOIUrl":"https://doi.org/10.1007/s00108-025-01863-y","url":null,"abstract":"<p><p>A 69-year-old female patient with known recurrence of esophageal cancer presented with fever and elevated inflammatory markers. In the recent past, a suspicious mediastinal lymph node had been biopsied via bronchoscopy. Consequently, a lymph node abscess developed, leading to blood stream infection (pathogen: Streptococcus anginosus) via a fistula into the superior vena cava. Through a preexisting atrial septal defect, the infection also spread to the brain, causing multiple brain abscesses.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1007/s00108-025-01852-1
Ulrich Matt, Sirka Nitschmann, Susanne Herold
{"title":"[Real world data show effectiveness of new respiratory syncytial virus (RSV) vaccines].","authors":"Ulrich Matt, Sirka Nitschmann, Susanne Herold","doi":"10.1007/s00108-025-01852-1","DOIUrl":"https://doi.org/10.1007/s00108-025-01852-1","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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