首页 > 最新文献

International journal of oral implantology (Berlin, Germany)最新文献

英文 中文
Prosthetics as a predisposing factor for peri-implantitis. 假体是种植体周围炎的诱发因素。
Jonathan Misch, Alberto Monje, Hom-Lay Wang
{"title":"Prosthetics as a predisposing factor for peri-implantitis.","authors":"Jonathan Misch, Alberto Monje, Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"15 3","pages":"203-204"},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33454734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term effects of titanium-base abutments on peri-implant health: A 5-year randomised controlled trial. 钛基基牙对种植体周围健康的长期影响:一项5年随机对照试验
Florian Rathe, Rüdiger Junker, Christian Heumann, Julia Blumenröhr, Thorsten Auschill, Nicole Arweiler, Markus Schlee

Purpose: Titanium bases are used frequently in daily practice for bonding to CAD/CAM abutments or crowns. Due to intimate contact between the adhesive gap of the titanium-base abutment and the peri-implant bone, the physical and chemical characteristics of the bonding material, or the gap itself, may affect peri-implant inflammatory reactions. The present study therefore aimed to examine the long-term effects of individualised abutments bonded to titanium bases on peri-implant health.

Materials and methods: A total of 24 patients, each with one test and one control abutment, participated in the present prospective, single-blind, randomised controlled clinical trial. The test abutments were CAD/CAM titanium abutments bonded to titanium bases. As the control abutments were individualised, one-piece CAD/CAM titanium abutments were used. Clinical and radiographic parameters were assessed at abutment insertion and then on a yearly basis over the following 5 years.

Results: No significant differences in marginal bone level were observed between the titanium-base and one-piece abutments at any of the follow-up time points; however, when intragroup marginal bone levels were compared to the baseline values, significant differences were found at several follow-up time points. Intergroup differences were only found to be significant for pocket depth at the 4- (P = 0.006) and 5-year follow-ups (P = 0.024), favouring titanium-base abutments.

Conclusions: Within the limitations of the present study, it appears that the peri-implant tissues of this specific patient cohort responded to titanium-base abutments in a rather similar manner to one-piece abutments over a 5-year period; however, no definitive conclusions can be drawn due to the low power of the present study.

用途:钛基托在日常实践中经常用于连接CAD/CAM基台或冠。钛基基基牙的粘接剂间隙与种植周骨紧密接触,粘接剂材料的物理化学特性或间隙本身都可能影响种植周骨的炎症反应。因此,本研究旨在检查与钛基结合的个体化基台对种植体周围健康的长期影响。材料与方法:本研究为前瞻性、单盲、随机对照临床试验,共24例患者,每例患者设1个试验组和1个对照基台。试验基台采用CAD/CAM钛基台与钛基台结合。由于对照基台是个体化的,因此使用了一体式CAD/CAM钛基台。在基台插入时评估临床和影像学参数,然后在接下来的5年中每年评估一次。结果:随访各时间点钛基基与一体式基牙的边缘骨水平无明显差异;然而,当将组内边缘骨水平与基线值进行比较时,在几个随访时间点发现显著差异。组间差异仅在4- (P = 0.006)和5年随访时(P = 0.024)发现袋深有显著性,有利于钛基基牙。结论:在本研究的限制下,在5年的时间里,这一特定患者群体的种植体周围组织对钛基基牙的反应与一件式基牙相当相似;然而,由于本研究的有效性较低,无法得出明确的结论。
{"title":"Long-term effects of titanium-base abutments on peri-implant health: A 5-year randomised controlled trial.","authors":"Florian Rathe,&nbsp;Rüdiger Junker,&nbsp;Christian Heumann,&nbsp;Julia Blumenröhr,&nbsp;Thorsten Auschill,&nbsp;Nicole Arweiler,&nbsp;Markus Schlee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>Titanium bases are used frequently in daily practice for bonding to CAD/CAM abutments or crowns. Due to intimate contact between the adhesive gap of the titanium-base abutment and the peri-implant bone, the physical and chemical characteristics of the bonding material, or the gap itself, may affect peri-implant inflammatory reactions. The present study therefore aimed to examine the long-term effects of individualised abutments bonded to titanium bases on peri-implant health.</p><p><strong>Materials and methods: </strong>A total of 24 patients, each with one test and one control abutment, participated in the present prospective, single-blind, randomised controlled clinical trial. The test abutments were CAD/CAM titanium abutments bonded to titanium bases. As the control abutments were individualised, one-piece CAD/CAM titanium abutments were used. Clinical and radiographic parameters were assessed at abutment insertion and then on a yearly basis over the following 5 years.</p><p><strong>Results: </strong>No significant differences in marginal bone level were observed between the titanium-base and one-piece abutments at any of the follow-up time points; however, when intragroup marginal bone levels were compared to the baseline values, significant differences were found at several follow-up time points. Intergroup differences were only found to be significant for pocket depth at the 4- (P = 0.006) and 5-year follow-ups (P = 0.024), favouring titanium-base abutments.</p><p><strong>Conclusions: </strong>Within the limitations of the present study, it appears that the peri-implant tissues of this specific patient cohort responded to titanium-base abutments in a rather similar manner to one-piece abutments over a 5-year period; however, no definitive conclusions can be drawn due to the low power of the present study.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"15 2","pages":"167-179"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10514341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significance of probing for monitoring peri-implant diseases. 探查对种植体周围疾病监测的意义。
Alberto Monje, Ettore Amerio, Roberto Farina, José Nart, Ausra Ramanauskaite, Stefan Renvert, Andrea Roccuzzo, Giovanni E Salvi, Frank Schwarz, Leonardo Trombelli, Hom-Lay Wang

Peri-implant diseases at implant sites represent the most considerable concern for many dental clinicians nowadays due to their detrimental effect on implant longevity. Preventive measures include patient education and motivation, supportive peri-implant therapy and routine assessment of the hard and soft tissues. Nevertheless, the reliability of clinical parameters to monitor peri-implant conditions is subject to debate. As such, the primary purpose of the present review was to gain further insight into the diagnostic accuracy of probing as a clinical tool to monitor dental implants and assist clinicians in preventing peri-implant diseases. Studies have recommended periodic probing to monitor the condition of the peri-implant tissues. Increased probing pocket depth, profuse bleeding on probing and suppuration at implants are clinical signs that have been associated with peri-implantitis; thus, if these clinical parameters are present, radiographic assessment is encouraged to make a definitive diagnosis considering potential inaccuracies related to local and/or systemic factors identified in the present review.

由于种植体周围疾病对种植体寿命的不利影响,目前许多牙科临床医生都非常关注种植体周围疾病。预防措施包括患者教育和激励,支持种植体周围治疗和硬软组织常规评估。然而,监测种植体周围情况的临床参数的可靠性仍存在争议。因此,本综述的主要目的是进一步了解探探作为监测种植体的临床工具的诊断准确性,并协助临床医生预防种植体周围疾病。研究建议定期探查以监测种植体周围组织的状况。探查袋深度增加、探查时大量出血和植入物处化脓是与植入物周围炎相关的临床症状;因此,如果存在这些临床参数,考虑到与本综述中确定的局部和/或全身因素相关的潜在不准确性,鼓励放射学评估做出明确的诊断。
{"title":"Significance of probing for monitoring peri-implant diseases.","authors":"Alberto Monje,&nbsp;Ettore Amerio,&nbsp;Roberto Farina,&nbsp;José Nart,&nbsp;Ausra Ramanauskaite,&nbsp;Stefan Renvert,&nbsp;Andrea Roccuzzo,&nbsp;Giovanni E Salvi,&nbsp;Frank Schwarz,&nbsp;Leonardo Trombelli,&nbsp;Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Peri-implant diseases at implant sites represent the most considerable concern for many dental clinicians nowadays due to their detrimental effect on implant longevity. Preventive measures include patient education and motivation, supportive peri-implant therapy and routine assessment of the hard and soft tissues. Nevertheless, the reliability of clinical parameters to monitor peri-implant conditions is subject to debate. As such, the primary purpose of the present review was to gain further insight into the diagnostic accuracy of probing as a clinical tool to monitor dental implants and assist clinicians in preventing peri-implant diseases. Studies have recommended periodic probing to monitor the condition of the peri-implant tissues. Increased probing pocket depth, profuse bleeding on probing and suppuration at implants are clinical signs that have been associated with peri-implantitis; thus, if these clinical parameters are present, radiographic assessment is encouraged to make a definitive diagnosis considering potential inaccuracies related to local and/or systemic factors identified in the present review.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"385-399"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39850056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of air-polishing devices without removal of implant-supported full-arch prostheses. 不移除种植体全弓假体的空气抛光装置的疗效。
Maria Menini, Francesca Delucchi, Francesco Bagnasco, Francesco Pera, Nicolò Di Tullio, Paolo Pesce

Purpose: Long-term success of titanium dental implants is influenced by various factors, including the maintenance of good oral hygiene. The present study aimed to evaluate cleaning effectiveness and patient satisfaction with glycine powder air polishing and traditional professional oral hygiene treatments when applied to implant-supported full-arch restorations without removal of the fixed prosthesis.

Materials and methods: A total of 85 patients with 357 implants supporting full-arch fixed restorations were included. After removal of the prosthesis (T0), the following parameters were recorded: Plaque Index, peri-implant spontaneous bleeding, probing depth and bleeding on probing. The prosthesis was then reinserted. The patients were divided into three groups, each of which received two hygiene therapies randomly administered in each hemiarch using a split-mouth design. The possible treatments were glycine powder air polishing and use of sponge floss vs sponge floss only in group 1; glycine powder air polishing vs use of an ultrasonic device with a polyetheretherketone fibre tip coating in group 2; and glycine powder air polishing vs use of carbon fibre curettes and sponge floss in group 3. After instrumentation, the prostheses were removed to assess the Plaque Index and peri-implant spontaneous bleeding. Questionnaires were used to record patients' levels of comfort and satisfaction in relation to the various treatments.

Results: Glycine powder air polishing resulted in a significantly higher reduction in plaque around implants compared to control treatments (sponge floss only, ultrasonic device with polyetheretherketone fibre tip coating, and manual scaling with carbon fibre curettes and use of sponge floss) (P = 0.020). Glycine powder air polishing followed by application of sponge floss provided the greatest reduction of plaque deposits on the prosthetic surfaces. On average, 80% of patients rated glycine powder air polishing highest with regard to satisfaction.

Conclusions: Glycine powder air polishing is a highly effective and comfortable treatment to maintain good oral hygiene in clinical practice, and could be used as an alternative to manual and mechanical instrumentation when dealing with implant-supported restorations.

目的:钛牙种植体的长期成功受多种因素的影响,包括保持良好的口腔卫生。本研究旨在评估甘氨酸粉末空气抛光和传统专业口腔卫生治疗在不拔除固定义齿的种植全弓修复中的清洁效果和患者满意度。材料和方法:共纳入85例患者,357颗种植体支持全弓固定修复。取出假体(T0)后,记录菌斑指数、种植体周围自发性出血、探入深度、探入时出血。然后重新植入假体。患者被分为三组,每组接受两种卫生疗法,随机在每个出血点使用开口设计。1组可能的处理方法为甘氨酸粉空气抛光和使用海绵牙线vs只使用海绵牙线;甘氨酸粉末空气抛光vs使用超声装置与聚醚醚酮纤维尖端涂层(组2);第三组甘氨酸粉末空气抛光与使用碳纤维刮管和海绵牙线。固定后,取出假体以评估斑块指数和种植体周围自发性出血。调查问卷用于记录患者对各种治疗方法的舒适度和满意度。结果:甘氨酸粉空气抛光导致种植体周围菌斑的减少明显高于对照处理(仅使用海绵牙线,超声装置与聚醚醚酮纤维尖端涂层,人工刮除碳纤维刮管和使用海绵牙线)(P = 0.020)。甘氨酸粉末空气抛光,然后应用海绵牙线提供了最大的减少斑块沉积在假体表面。平均而言,80%的患者对甘氨酸粉末空气抛光的满意度最高。结论:甘氨酸粉空气抛光在临床上是一种高效、舒适的口腔清洁方法,可作为人工和机械器械的替代方法用于种植体修复。
{"title":"Efficacy of air-polishing devices without removal of implant-supported full-arch prostheses.","authors":"Maria Menini,&nbsp;Francesca Delucchi,&nbsp;Francesco Bagnasco,&nbsp;Francesco Pera,&nbsp;Nicolò Di Tullio,&nbsp;Paolo Pesce","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>Long-term success of titanium dental implants is influenced by various factors, including the maintenance of good oral hygiene. The present study aimed to evaluate cleaning effectiveness and patient satisfaction with glycine powder air polishing and traditional professional oral hygiene treatments when applied to implant-supported full-arch restorations without removal of the fixed prosthesis.</p><p><strong>Materials and methods: </strong>A total of 85 patients with 357 implants supporting full-arch fixed restorations were included. After removal of the prosthesis (T0), the following parameters were recorded: Plaque Index, peri-implant spontaneous bleeding, probing depth and bleeding on probing. The prosthesis was then reinserted. The patients were divided into three groups, each of which received two hygiene therapies randomly administered in each hemiarch using a split-mouth design. The possible treatments were glycine powder air polishing and use of sponge floss vs sponge floss only in group 1; glycine powder air polishing vs use of an ultrasonic device with a polyetheretherketone fibre tip coating in group 2; and glycine powder air polishing vs use of carbon fibre curettes and sponge floss in group 3. After instrumentation, the prostheses were removed to assess the Plaque Index and peri-implant spontaneous bleeding. Questionnaires were used to record patients' levels of comfort and satisfaction in relation to the various treatments.</p><p><strong>Results: </strong>Glycine powder air polishing resulted in a significantly higher reduction in plaque around implants compared to control treatments (sponge floss only, ultrasonic device with polyetheretherketone fibre tip coating, and manual scaling with carbon fibre curettes and use of sponge floss) (P = 0.020). Glycine powder air polishing followed by application of sponge floss provided the greatest reduction of plaque deposits on the prosthetic surfaces. On average, 80% of patients rated glycine powder air polishing highest with regard to satisfaction.</p><p><strong>Conclusions: </strong>Glycine powder air polishing is a highly effective and comfortable treatment to maintain good oral hygiene in clinical practice, and could be used as an alternative to manual and mechanical instrumentation when dealing with implant-supported restorations.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"401-416"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39850057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis: A systematic review and meta-analysis based on animal model studies. 种植体表面特征对种植体周围炎的发生、进展和治疗结果的影响:基于动物模型研究的系统回顾和荟萃分析
Carlos Garaicoa-Pazmino, Guo-Hao Lin, Aaeshah Alkandery, Carlos Parra-Carrasquer, Fernando Suárez-López Del Amo

Purpose: To evaluate the impact of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis based exclusively on in vivo investigations.

Materials and methods: A literature search was conducted by two independent reviewers following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify animal studies comparing at least two different implant surfaces affected by experimental peri-implantitis, with distinct characteristics and with or without subsequent surgical treatment that aims to arrest disease progression. The parameters evaluated included both radiographic (e.g., marginal bone level) and clinical (e.g., probing depth, bleeding on probing) aspects to determine changes in disease progression and treatment outcomes.

Results: No statistically significant differences were found among the different implant surfaces during the initiation of peri-implantitis. On the other hand, the progression and treatment outcomes of peri-implantitis displayed statistically significant differences among the different implant systems, with turned surfaces reporting less bone loss during the progression period and greater bone gain after treatment.

Conclusions: Implant surface characteristics play a critical role in the progression and treatment outcomes of peri-implantitis. Turned implant surfaces demonstrated the least amount of bone loss after ligature removal and recorded the most favourable treatment outcomes.

目的:基于体内研究,评估种植体表面特征对种植体周围炎的发生、发展和治疗结果的影响。材料和方法:由两名独立审稿人根据系统评价和荟萃分析指南的首选报告项目进行文献检索,以确定比较至少两种不同种植体表面受实验性种植体周围炎影响的动物研究,这些研究具有不同的特征,并有或没有后续手术治疗以阻止疾病进展。评估的参数包括放射学(例如,边缘骨水平)和临床(例如,探探深度,探探时出血)方面,以确定疾病进展和治疗结果的变化。结果:种植体周围炎发生时不同种植体表面间差异无统计学意义。另一方面,种植体周围炎的进展和治疗结果在不同种植体系统之间有统计学上的差异,在进展期间翻转表面的骨质流失较少,治疗后骨质增加较多。结论:种植体表面特征对种植体周围炎的进展和治疗效果起着至关重要的作用。扭转种植体表面显示结扎去除后骨质流失最少,并记录了最有利的治疗结果。
{"title":"Influence of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis: A systematic review and meta-analysis based on animal model studies.","authors":"Carlos Garaicoa-Pazmino,&nbsp;Guo-Hao Lin,&nbsp;Aaeshah Alkandery,&nbsp;Carlos Parra-Carrasquer,&nbsp;Fernando Suárez-López Del Amo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis based exclusively on in vivo investigations.</p><p><strong>Materials and methods: </strong>A literature search was conducted by two independent reviewers following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify animal studies comparing at least two different implant surfaces affected by experimental peri-implantitis, with distinct characteristics and with or without subsequent surgical treatment that aims to arrest disease progression. The parameters evaluated included both radiographic (e.g., marginal bone level) and clinical (e.g., probing depth, bleeding on probing) aspects to determine changes in disease progression and treatment outcomes.</p><p><strong>Results: </strong>No statistically significant differences were found among the different implant surfaces during the initiation of peri-implantitis. On the other hand, the progression and treatment outcomes of peri-implantitis displayed statistically significant differences among the different implant systems, with turned surfaces reporting less bone loss during the progression period and greater bone gain after treatment.</p><p><strong>Conclusions: </strong>Implant surface characteristics play a critical role in the progression and treatment outcomes of peri-implantitis. Turned implant surfaces demonstrated the least amount of bone loss after ligature removal and recorded the most favourable treatment outcomes.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"367-382"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39836696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Horizontal bone augmentation of the edentulous area with simultaneous endodontic microsurgery of the adjacent tooth: A digitally-driven multidisciplinary case report with a 1-year follow-up. 无牙区水平骨增强术同时邻牙根管显微手术:一个数字驱动的多学科病例报告,随访1年。
Jing Wang, Yilin Luo, Xuelian Tan, Chenbing Wang, Vicha Huangphattarakul, Chen Hu, Dingming Hang, Yi Man

Purpose: To introduce a novel and efficient procedure to solve a multidisciplinary issue connected to implant-related surgery in areas near periapical lesions of adjacent teeth using single-stage combined surgery while exploring a new way to prevent retrograde peri-implantitis.

Materials and methods: A 31-year-old woman diagnosed with a Kennedy III dentition defect in the maxillary right central incisor and posttreatment apical periodontitis in the maxillary right lateral incisor was treated using a multidisciplinary procedure. First, the preoperative data were collected from intraoral, extraoral facial and CBCT scans. Then, the aesthetic appearance of the anterior teeth was planned digitally and implant insertion was simulated. Next, virtual bone augmentation was carried out with reference to the simulated implant position, and according to the virtual augmentation, the templates for bone shell harvesting (also used for apical osteotomy and root tip resection during endodontic microsurgery) and bone shell grafting of the edentulous area were designed and fabricated. The templates for combined surgery (endodontic microsurgery and horizontal bone augmentation) consisted of one basal template and multiple interchangeable attachments via a plugin design to make guided endodontic microsurgery and digitally guided bone augmentation more efficient. Combined surgery was then carried out using the templates for guidance. During surgery, the apical inflammation affecting the maxillary right lateral incisor was first removed and its preserved apical bony window was prepared as an autogenous bone shell for bone augmentation of the maxillary right central incisor site. Guided bone regeneration of the edentulous area and guided tissue regeneration were then performed for the adjacent tooth. Six months after the combined surgery, digital guided implant surgery was carried out for the edentulous area. The final prosthesis was delivered in accordance with the preoperative aesthetic design and achieved using an implant-supported restoration for the maxillary right central incisor, full crown restoration for the maxillary right lateral incisor, and ceramic veneers for the maxillary left central and lateral incisors for space closure.

Results: The horizontal bone augmentation in the edentulous area and endodontic microsurgery on the neighbouring tooth were performed successfully in a single-stage surgical procedure; thus, augmentation of the resorbed alveolar bone and removal of infection in the adjacent site were achieved simultaneously. At the 1-year follow-up after combined surgery, the healing of the natural maxillary right lateral incisor and the area having undergone bone augmentation showed promising results with no postoperative complications.

Conclusions: This novel digital workflow appears effective in addressing the problem of periapical lesions in retained teeth adj

目的:介绍一种新颖、高效的方法,解决邻近牙尖周病变附近种植体相关手术的多学科问题,同时探索预防种植体周围逆行性炎的新方法。材料和方法:一名31岁的女性,诊断为上颌右中切牙肯尼迪III型牙列缺损,上颌右侧切牙治疗后根尖牙周炎,采用多学科手术治疗。首先,术前数据收集自口腔内、口腔外面部和CBCT扫描。然后,数字化规划前牙的美观外观,模拟种植体的插入。然后,参照模拟种植体位置进行虚拟骨增强,根据虚拟骨增强设计制作无牙区骨壳收获(也可用于牙髓显微手术中根尖截骨和根尖截骨)和骨壳移植模板。结合手术模板(根管显微手术和水平骨增强)由一个基底模板和多个可互换的附着体组成,通过插件设计,提高了引导根管显微手术和数字引导骨增强的效率。然后在模板指导下进行联合手术。术中首先切除影响上颌右侧切牙的根尖炎症,并制备其保留的根尖骨窗作为自体骨壳,用于上颌右中切牙部位的骨增强。对无牙区进行引导骨再生,对邻牙进行引导组织再生。联合手术6个月后,对无牙区行数字引导种植手术。最终假体按照术前美学设计交付,并使用种植体支持修复上颌右中切牙,全冠修复上颌右侧切牙,陶瓷贴面修复上颌左中切牙和侧切牙的间隙。结果:无牙区水平骨增加术和邻牙根管显微手术均在一次手术中成功完成;因此,增加被吸收的牙槽骨,同时消除邻近部位的感染。联合手术后1年随访,上颌自然右侧切牙及隆骨区愈合情况良好,无术后并发症。结论:这种新颖的数字化工作流程有效地解决了无牙区附近保留牙的根尖周病变问题,这些问题需要一次手术进行水平骨增强,提供了一种有效的方法来解决使用牙髓学和种植学的问题,并防止逆行性种植周围炎。
{"title":"Horizontal bone augmentation of the edentulous area with simultaneous endodontic microsurgery of the adjacent tooth: A digitally-driven multidisciplinary case report with a 1-year follow-up.","authors":"Jing Wang,&nbsp;Yilin Luo,&nbsp;Xuelian Tan,&nbsp;Chenbing Wang,&nbsp;Vicha Huangphattarakul,&nbsp;Chen Hu,&nbsp;Dingming Hang,&nbsp;Yi Man","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To introduce a novel and efficient procedure to solve a multidisciplinary issue connected to implant-related surgery in areas near periapical lesions of adjacent teeth using single-stage combined surgery while exploring a new way to prevent retrograde peri-implantitis.</p><p><strong>Materials and methods: </strong>A 31-year-old woman diagnosed with a Kennedy III dentition defect in the maxillary right central incisor and posttreatment apical periodontitis in the maxillary right lateral incisor was treated using a multidisciplinary procedure. First, the preoperative data were collected from intraoral, extraoral facial and CBCT scans. Then, the aesthetic appearance of the anterior teeth was planned digitally and implant insertion was simulated. Next, virtual bone augmentation was carried out with reference to the simulated implant position, and according to the virtual augmentation, the templates for bone shell harvesting (also used for apical osteotomy and root tip resection during endodontic microsurgery) and bone shell grafting of the edentulous area were designed and fabricated. The templates for combined surgery (endodontic microsurgery and horizontal bone augmentation) consisted of one basal template and multiple interchangeable attachments via a plugin design to make guided endodontic microsurgery and digitally guided bone augmentation more efficient. Combined surgery was then carried out using the templates for guidance. During surgery, the apical inflammation affecting the maxillary right lateral incisor was first removed and its preserved apical bony window was prepared as an autogenous bone shell for bone augmentation of the maxillary right central incisor site. Guided bone regeneration of the edentulous area and guided tissue regeneration were then performed for the adjacent tooth. Six months after the combined surgery, digital guided implant surgery was carried out for the edentulous area. The final prosthesis was delivered in accordance with the preoperative aesthetic design and achieved using an implant-supported restoration for the maxillary right central incisor, full crown restoration for the maxillary right lateral incisor, and ceramic veneers for the maxillary left central and lateral incisors for space closure.</p><p><strong>Results: </strong>The horizontal bone augmentation in the edentulous area and endodontic microsurgery on the neighbouring tooth were performed successfully in a single-stage surgical procedure; thus, augmentation of the resorbed alveolar bone and removal of infection in the adjacent site were achieved simultaneously. At the 1-year follow-up after combined surgery, the healing of the natural maxillary right lateral incisor and the area having undergone bone augmentation showed promising results with no postoperative complications.</p><p><strong>Conclusions: </strong>This novel digital workflow appears effective in addressing the problem of periapical lesions in retained teeth adj","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"435-451"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39850060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Peri-implant disease: collaboration and consensus. 社论:种植体周围疾病:合作与共识。
Craig M Misch, Hom-Lay Wang
{"title":"Editorial: Peri-implant disease: collaboration and consensus.","authors":"Craig M Misch,&nbsp;Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"343-344"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39836693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 20-year split-mouth comparative study of two screw-shaped titanium implant systems. 两种螺旋形钛种植体系统20年裂口比较研究。
Reinhilde Jacobs, Yifei Gu, Marc Quirynen, Greet De Mars, Christel Dekeyser, Daniel van Steenberghe, Dirk Vrombaut, Sohaib Shujaat, Ignace Naert

Purpose: To prospectively assess marginal bone loss and implant survival with Astra Tech (Dentsply Sirona, Charlotte, NC, USA) (group A) and Brånemark (Nobel Biocare, Zurich, Switzerland) (group B) implants in a split-mouth study conducted over a 20-year follow-up period.

Materials and methods: A total of 95 implants (n = 50, group A and n = 45, group B) were randomly placed in the left or right side of the maxilla or mandible in 18 patients. Clinical and radiographic examinations were performed, and results were reported at 5, 10, 15 and 20 years after insertion of the prosthesis.

Results: Ten patients were followed up for 20 years (n = 26 implants, group A and n = 25 implants, group B). No implant loss or prosthetic failures were observed. After 20 years of follow-up, no significant differences in marginal bone loss were found between both implant groups (P = 0.25). The proportion of marginal bone loss ≥ 0.5 mm was not significantly different between implant types (P > 0.05), and no statistically significant relationships were found between marginal bone loss and time (P ≥ 0.05). More specifically, there was no significant difference in marginal bone level between year 20 and baseline in group A (P = 0.70), whereas a difference of 0.5 to 1.0 mm was found in group B (P = 0.15).

Conclusions: After 20 years of follow-up, marginal bone loss around screw-shaped titanium implants was clinically insignificant. Furthermore, no significant differences in survival and marginal bone loss were found between group A and B implants over the follow-up period.

目的:前瞻性评估Astra Tech (Dentsply Sirona, Charlotte, NC, USA) (A组)和br nemark (Nobel Biocare, Zurich, Switzerland) (B组)种植体在20年随访期的开口研究中的边缘骨丢失和种植体存活率。材料与方法:18例患者共95颗种植体(A组n = 50, B组n = 45),随机放置于上颌或下颌骨左侧或右侧。进行了临床和影像学检查,并报告了植入假体后5年、10年、15年和20年的结果。结果:10例患者随访20年(A组n = 26个种植体,B组n = 25个种植体),未见种植体丢失或假体失效。随访20年后,两种种植体组的边缘骨质流失无显著差异(P = 0.25)。≥0.5 mm的边缘骨质流失比例在种植体类型间差异无统计学意义(P > 0.05),边缘骨质流失与时间间关系无统计学意义(P≥0.05)。更具体地说,A组的边缘骨水平在20年与基线之间没有显著差异(P = 0.70),而B组的差异为0.5至1.0 mm (P = 0.15)。结论:经过20年的随访,临床上螺钉状钛种植体周围边缘骨丢失不明显。此外,在随访期间,A组和B组种植体的存活率和边缘骨质流失没有显着差异。
{"title":"A 20-year split-mouth comparative study of two screw-shaped titanium implant systems.","authors":"Reinhilde Jacobs,&nbsp;Yifei Gu,&nbsp;Marc Quirynen,&nbsp;Greet De Mars,&nbsp;Christel Dekeyser,&nbsp;Daniel van Steenberghe,&nbsp;Dirk Vrombaut,&nbsp;Sohaib Shujaat,&nbsp;Ignace Naert","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To prospectively assess marginal bone loss and implant survival with Astra Tech (Dentsply Sirona, Charlotte, NC, USA) (group A) and Brånemark (Nobel Biocare, Zurich, Switzerland) (group B) implants in a split-mouth study conducted over a 20-year follow-up period.</p><p><strong>Materials and methods: </strong>A total of 95 implants (n = 50, group A and n = 45, group B) were randomly placed in the left or right side of the maxilla or mandible in 18 patients. Clinical and radiographic examinations were performed, and results were reported at 5, 10, 15 and 20 years after insertion of the prosthesis.</p><p><strong>Results: </strong>Ten patients were followed up for 20 years (n = 26 implants, group A and n = 25 implants, group B). No implant loss or prosthetic failures were observed. After 20 years of follow-up, no significant differences in marginal bone loss were found between both implant groups (P = 0.25). The proportion of marginal bone loss ≥ 0.5 mm was not significantly different between implant types (P > 0.05), and no statistically significant relationships were found between marginal bone loss and time (P ≥ 0.05). More specifically, there was no significant difference in marginal bone level between year 20 and baseline in group A (P = 0.70), whereas a difference of 0.5 to 1.0 mm was found in group B (P = 0.15).</p><p><strong>Conclusions: </strong>After 20 years of follow-up, marginal bone loss around screw-shaped titanium implants was clinically insignificant. Furthermore, no significant differences in survival and marginal bone loss were found between group A and B implants over the follow-up period.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"421-430"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39850059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The coronally advanced flap technique revisited: Treatment of peri-implant soft tissue dehiscences. 冠状先进皮瓣技术:种植体周围软组织裂开的治疗。
Giovanni Zucchelli, Lorenzo Tavelli, Martina Stefanini, Shayan Barootchi, Hom-Lay Wang

The coronally advanced flap technique is one of the most commonly used approaches for treating gingival recession. Several modifications of the technique have been proposed over the years, making it a highly predictable treatment option for gingival recession; however, as dental implants are structurally and biologically different from natural teeth, a further modification of the conventional coronally advanced flap technique has been suggested to overcome the challenges posed by the treatment of peri-implant soft tissue dehiscences. The present article aims to describe the state of the art of the technique at implant sites presenting with peri-implant soft tissue dehiscences, and highlight the main differences between this and the coronally advanced flap approach in natural teeth. The timing of crown removal and abutment modification/replacement are discussed, along with the different methods for management of the flap and connective tissue graft that are recommended at implant sites. The outcomes of this approach compared to the conventional coronally advanced flap technique, and other approaches are also presented.

冠状推进瓣技术是治疗牙龈退缩最常用的方法之一。多年来,已经提出了对该技术的几种修改,使其成为牙龈衰退的高度可预测的治疗选择;然而,由于牙种植体在结构和生物学上与天然牙齿不同,人们建议进一步改进传统的冠状先进皮瓣技术,以克服种植体周围软组织开裂的治疗带来的挑战。本文旨在描述该技术在种植体周围软组织开裂的种植体部位的现状,并强调该方法与自然牙冠上先进皮瓣方法之间的主要区别。讨论了冠移除和基台改良/替换的时机,以及在种植部位推荐的皮瓣和结缔组织移植物的不同处理方法。该方法的结果与传统冠状先进皮瓣技术和其他方法进行了比较。
{"title":"The coronally advanced flap technique revisited: Treatment of peri-implant soft tissue dehiscences.","authors":"Giovanni Zucchelli,&nbsp;Lorenzo Tavelli,&nbsp;Martina Stefanini,&nbsp;Shayan Barootchi,&nbsp;Hom-Lay Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The coronally advanced flap technique is one of the most commonly used approaches for treating gingival recession. Several modifications of the technique have been proposed over the years, making it a highly predictable treatment option for gingival recession; however, as dental implants are structurally and biologically different from natural teeth, a further modification of the conventional coronally advanced flap technique has been suggested to overcome the challenges posed by the treatment of peri-implant soft tissue dehiscences. The present article aims to describe the state of the art of the technique at implant sites presenting with peri-implant soft tissue dehiscences, and highlight the main differences between this and the coronally advanced flap approach in natural teeth. The timing of crown removal and abutment modification/replacement are discussed, along with the different methods for management of the flap and connective tissue graft that are recommended at implant sites. The outcomes of this approach compared to the conventional coronally advanced flap technique, and other approaches are also presented.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 4","pages":"351-365"},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39836694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vestibular socket therapy with immediate implant placement for managing compromised fresh extraction sockets: A prospective single-arm clinical study. 前庭窝治疗与立即植入处理受损新鲜拔牙窝:一项前瞻性单臂临床研究。
Abdelsalam Elaskary, Moataz Meabed, Iman Abd-ElWahab Radi

Purpose: To assess hard and soft tissues regenerated around immediate implants placed in compromised fresh extraction sockets using vestibular socket therapy 2 years postoperatively.

Materials and methods: Twenty-seven compromised fresh extraction sockets were managed using vestibular socket therapy and immediate implant placement. After immediate implant placement, a cortical bone shield was stabilised through a vestibular incision. The socket defect was filled with particulate bone graft. Labial plate thickness and bone height were evaluated 1 and 2 years postoperatively using CBCT. The pink aesthetic score and probing depth were recorded after 6 months, 1 year and 2 years. A Friedman test was used to study changes in the reported outcomes over time, with the level of statistical significance set at P ≤ 0.05.

Results: All implants recorded a 100.0% survival rate. A statistically significant increase in bone height (0.93 mm, P = 0.004) and apical (0.12 mm, P = 0.026), midfacial (1.26 mm, P < 0.001) and crestal (0.86 mm, P < 0.001) bone thickness was observed after 2 years. The changes in pink aesthetic score and probing depth were not significant: the pink aesthetic score was 12.48 ± 1.45 and the mean PD was 2.37 ± 0.79 mm mesially, 2.11 ± 0.70 mm facially, 2.07 ± 1.04 mm distally and 1.00 ± 0.00 mm palatally after 2 years.

Conclusion: Combining immediate implant placement with vestibular socket therapy to manage compromised fresh extraction sockets offers promising radiographic, aesthetic and periodontal results while minimising the treatment time and number of surgical procedures required.

目的:评估在受损的新鲜拔牙槽内使用前庭槽治疗2年后立即种植体周围的硬软组织再生情况。材料和方法:27个受损的新鲜拔牙槽采用前庭槽治疗和立即种植。即刻植入后,通过前庭切口稳定皮质骨盾牌。骨窝缺损用颗粒骨移植物填充。术后1年和2年用CBCT评估唇板厚度和骨高度。术后6个月、1年、2年分别记录粉红色美学评分和探探深度。采用Friedman检验研究报告结果随时间的变化,P≤0.05为统计学显著性水平。结果:所有种植体成活率均为100.0%。2年后,骨高(0.93 mm, P = 0.004)、骨尖(0.12 mm, P = 0.026)、面中(1.26 mm, P < 0.001)、嵴(0.86 mm, P < 0.001)骨厚均有统计学意义的增加。2年后,粉色美学评分和探探深度的变化不显著:粉红色美学评分为12.48±1.45,平均PD为近端2.37±0.79 mm,面2.11±0.70 mm,远端2.07±1.04 mm,上颚1.00±0.00 mm。结论:结合前庭牙槽治疗治疗受损的新鲜拔牙槽提供了有希望的放射学,美学和牙周效果,同时最大限度地减少了治疗时间和所需的手术次数。
{"title":"Vestibular socket therapy with immediate implant placement for managing compromised fresh extraction sockets: A prospective single-arm clinical study.","authors":"Abdelsalam Elaskary,&nbsp;Moataz Meabed,&nbsp;Iman Abd-ElWahab Radi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To assess hard and soft tissues regenerated around immediate implants placed in compromised fresh extraction sockets using vestibular socket therapy 2 years postoperatively.</p><p><strong>Materials and methods: </strong>Twenty-seven compromised fresh extraction sockets were managed using vestibular socket therapy and immediate implant placement. After immediate implant placement, a cortical bone shield was stabilised through a vestibular incision. The socket defect was filled with particulate bone graft. Labial plate thickness and bone height were evaluated 1 and 2 years postoperatively using CBCT. The pink aesthetic score and probing depth were recorded after 6 months, 1 year and 2 years. A Friedman test was used to study changes in the reported outcomes over time, with the level of statistical significance set at P ≤ 0.05.</p><p><strong>Results: </strong>All implants recorded a 100.0% survival rate. A statistically significant increase in bone height (0.93 mm, P = 0.004) and apical (0.12 mm, P = 0.026), midfacial (1.26 mm, P < 0.001) and crestal (0.86 mm, P < 0.001) bone thickness was observed after 2 years. The changes in pink aesthetic score and probing depth were not significant: the pink aesthetic score was 12.48 ± 1.45 and the mean PD was 2.37 ± 0.79 mm mesially, 2.11 ± 0.70 mm facially, 2.07 ± 1.04 mm distally and 1.00 ± 0.00 mm palatally after 2 years.</p><p><strong>Conclusion: </strong>Combining immediate implant placement with vestibular socket therapy to manage compromised fresh extraction sockets offers promising radiographic, aesthetic and periodontal results while minimising the treatment time and number of surgical procedures required.</p>","PeriodicalId":73463,"journal":{"name":"International journal of oral implantology (Berlin, Germany)","volume":"14 3","pages":"307-320"},"PeriodicalIF":0.0,"publicationDate":"2021-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39328984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International journal of oral implantology (Berlin, Germany)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1