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Arterial Spin Labelling-Based Blood-Brain Barrier Assessment and Its Applications. 基于动脉自旋标记的血脑屏障评估及其应用
Investigative magnetic resonance imaging
Pub Date : 2022-12-01 Epub Date: 2022-12-31 DOI: 10.13104/imri.2022.26.4.229
Yiran Li, Alishba Sadiq, Ze Wang

The brain relies on the blood-brain barrier (BBB) for the selective absorption of nutrients and the exclusion of other big molecules from the circulating blood. Therefore, the integrity of BBB is critical to brain health, and assessing BBB condition is of great clinical importance. BBB is often examined using exogenous tracers that can travel across the BBB, but the tracers might cause severe side effects. To avoid the use of external tracers, researchers have used magnetically labeled arterial blood as the endogenous tracer to assess the water permeability of BBB as a surrogate index of BBB. This paper reviews the three major types of Arterial Spin Labelling (ASL) based BBB water permeability assessment techniques and their applications in brain diseases such as Alzheimer's Disease.

大脑依靠血脑屏障（BBB）选择性地吸收营养物质，并将其他大分子物质排除在循环血液之外。因此，血脑屏障的完整性对大脑健康至关重要，评估血脑屏障的状况也具有重要的临床意义。通常使用可穿越 BBB 的外源性示踪剂来检查 BBB，但示踪剂可能会导致严重的副作用。为了避免使用外源性示踪剂，研究人员使用磁标记动脉血作为内源性示踪剂来评估 BBB 的水渗透性，以此作为 BBB 的替代指标。本文综述了三种主要的基于动脉自旋标记（ASL）的 BBB 水渗透性评估技术及其在阿尔茨海默病等脑部疾病中的应用。
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引用次数: 0
Tuberculous Epididymo-Orchitis with Multifocal Extrapulmonary Tuberculosis: a Case Report 结核性附睾-睾丸炎合并多灶性肺外结核1例
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.1.71
JI-JIANG An, K. Kim
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引用次数: 0
Optimization of Scan Parameters for in vivo Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging 体内超极化碳-13磁共振成像扫描参数的优化
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.2.125
Nguyen-Trong Nguyen, Onila Rasanjala, I. Park
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引用次数: 0
Deep Learning Applications in Perfusion MRI: Recent Advances and Current Challenges 深度学习在灌注MRI中的应用:最新进展和当前挑战
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.4.246
K. Choi
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引用次数: 1
Comparison of 2D Thin Section Dixon, 3D Isotropic SPACE, and 2D T2-Weighted Sequences in Ankle MRI 二维Dixon薄片、三维各向同性SPACE和二维t2加权序列在踝关节MRI中的比较
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.4.284
Tae Ran Ahn, Y. Jeong, J. Jeon, So Hyun Park, Sheen-Woo Lee
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引用次数: 0
Clinical Significance and Characteristics of Newly Detected Lesions on Breast MRI During Neoadjuvant Chemotherapy 新辅助化疗期间乳腺MRI新发现病灶的临床意义及特点
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.4.303
Kyeyoung Lee, K. J. Nam, K. Choo, S. Nam, Hyun Yul Kim, Y. Jung, Jae-Joon Kim, J. Joo, J. Kim, Ji Won Lee, Jae-Yeon Hwang, Chankue Park
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引用次数: 0
Two Cases of Herlyn-Werner-Wunderlich Syndrome herlin - werner - wunderlich综合征2例
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.3.166
Yuri Kim, Y. Ku, Y. Won
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引用次数: 0
Cerebral Amyloid Angiopathy Presenting as Cerebral Infarction in a Young Man: A Case Report 脑淀粉样血管病表现为脑梗死1例
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.3.171
Yun-Jeong Choi, J. Choi, Hyun Seok Choi, J. Byun, Eun Jeong Lee
{"title":"Cerebral Amyloid Angiopathy Presenting as Cerebral Infarction in a Young Man: A Case Report","authors":"Yun-Jeong Choi, J. Choi, Hyun Seok Choi, J. Byun, Eun Jeong Lee","doi":"10.13104/imri.2022.26.3.171","DOIUrl":"https://doi.org/10.13104/imri.2022.26.3.171","url":null,"abstract":"","PeriodicalId":73505,"journal":{"name":"Investigative magnetic resonance imaging","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66638154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic Angiomyolipoma Presenting as a Hyperintense Lesion During the Hepatobiliary Phase of Gadoxetic Acid Enhanced-MRI: a Case Report 肝血管平滑肌脂肪瘤在肝胆道期表现为高强度病变:1例报告
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.1.60
B. Jeong, So Yeon Kim, H. Kang, J. Shin
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引用次数: 0
MRI Features for Prediction Malignant Intra-Mammary Lymph Nodes: Correlations with Mammography and Ultrasound 预测恶性乳腺内淋巴结的MRI特征:与乳房x线摄影和超声的相关性
Investigative magnetic resonance imaging
Pub Date : 2022-01-01 DOI: 10.13104/imri.2022.26.2.135
Meejung Kim, B. Kang, G. Park
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引用次数: 1
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