Pub Date : 2018-01-01DOI: 10.4172/2324-9110-c3-013
J. Sprent
{"title":"Strong immunogenicity of membrane nanovesicles from dendritic cells","authors":"J. Sprent","doi":"10.4172/2324-9110-c3-013","DOIUrl":"https://doi.org/10.4172/2324-9110-c3-013","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-C6-023
S. Suchkov
{"title":"Abzymes as unique biomarkers and targets to monitor and manage chronic disorders and to serve tools for bioengineering of the next-step generation","authors":"S. Suchkov","doi":"10.4172/2324-9110-C6-023","DOIUrl":"https://doi.org/10.4172/2324-9110-C6-023","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-c1-009
Kow Koon Kee
{"title":"Synthesis and biological evaluation of new purine-like heterocyclic molecules targeting apoptosis in cancer cell lines","authors":"Kow Koon Kee","doi":"10.4172/2324-9110-c1-009","DOIUrl":"https://doi.org/10.4172/2324-9110-c1-009","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-c5-019
S. Naya
{"title":"Plasmonic photocatalyst: Hot electron transfer type and hot hole-transfer type","authors":"S. Naya","doi":"10.4172/2324-9110-c5-019","DOIUrl":"https://doi.org/10.4172/2324-9110-c5-019","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-C6-024
Y. Rahim
{"title":"Ki67 in young patients with breast cancer","authors":"Y. Rahim","doi":"10.4172/2324-9110-C6-024","DOIUrl":"https://doi.org/10.4172/2324-9110-C6-024","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-c4-017
Mosa Alhamami
{"title":"Manganese-Enhanced Magnetic Resonance Imaging of Breast Cancer Cells","authors":"Mosa Alhamami","doi":"10.4172/2324-9110-c4-017","DOIUrl":"https://doi.org/10.4172/2324-9110-c4-017","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2324-9110-c6-022
E. Strom
{"title":"Proton accelerated partial breast irradiation (APBI) has an exceptional patient satisfaction profile","authors":"E. Strom","doi":"10.4172/2324-9110-c6-022","DOIUrl":"https://doi.org/10.4172/2324-9110-c6-022","url":null,"abstract":"","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70250462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-05DOI: 10.4172/2324-9110.1000200
Numan Fateh
Mantle cell lymphoma (MCL) is a mature B-cell non-Hodgkin lymphoma that is relatively uncommon. MCL is an aggressive lymphoma and at times can share many features with chronic lymphocytic leukemia (CLL). CLL is positive for CD5+ (in 80% of cases), CD20+ (95%) and CD23+ (85%). MCL is also positive for CD5+ (80%) and CD20+ (94%), but generally negative for CD23-. However, there are cases of CD23 positive MCL which can lead to misdiagnosis. Cyclin D1 is more specific than CD markers, but is positive in approximately 85-90% of cases. Thus for 15% of cases this test is also not reliable to diagnose MCL. For example, there are reports of Cyclin D2 and Cyclin D3 involvement instead of the more commonly known Cyclin D1. The same is true for t (11;14) studies by Fluorescence in situ hybridization (FISH) for MCL. Though it is a rare entity, there are known cases of t (11;14) negative MCL. In cases such as these, it may be difficult to correctly diagnose MCL. Therefore, it is important to have an understanding of the similarities and differences of these two diseases and to be aware of the less commonly used tests to help differentiate between MCL and CLL.
{"title":"Mantle Cell Lymphoma Misdiagnosed as Chronic Lymphocytic Leukemia: Optimization of Diagnostic Approach","authors":"Numan Fateh","doi":"10.4172/2324-9110.1000200","DOIUrl":"https://doi.org/10.4172/2324-9110.1000200","url":null,"abstract":"Mantle cell lymphoma (MCL) is a mature B-cell non-Hodgkin lymphoma that is relatively uncommon. MCL is an aggressive lymphoma and at times can share many features with chronic lymphocytic leukemia (CLL). CLL is positive for CD5+ (in 80% of cases), CD20+ (95%) and CD23+ (85%). MCL is also positive for CD5+ (80%) and CD20+ (94%), but generally negative for CD23-. However, there are cases of CD23 positive MCL which can lead to misdiagnosis. Cyclin D1 is more specific than CD markers, but is positive in approximately 85-90% of cases. Thus for 15% of cases this test is also not reliable to diagnose MCL. For example, there are reports of Cyclin D2 and Cyclin D3 involvement instead of the more commonly known Cyclin D1. The same is true for t (11;14) studies by Fluorescence in situ hybridization (FISH) for MCL. Though it is a rare entity, there are known cases of t (11;14) negative MCL. In cases such as these, it may be difficult to correctly diagnose MCL. Therefore, it is important to have an understanding of the similarities and differences of these two diseases and to be aware of the less commonly used tests to help differentiate between MCL and CLL.","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47255040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-22DOI: 10.4172/2324-9110.1000207
I. Karampinis, Laura Schwarzwaelder, M. Hoffmann, T. Gaiser, K. Nowak, P. Hohenberger, J. Jakob
Purpose: Hyperthermic isolated limb perfusion (ILP) is a highly effective treatment option for locally advanced soft tissue sarcoma and in-transit metastasized malignant melanoma of the extremities. The role of the hyperthermic isolated limb perfusion in the treatment of aggressive cutaneous b-cell lymphoma (PCLBCL-LT) is unknown. Methods: This is a case presentation of a 65 year old woman with a multifocal recurrence of a cutaneous b-cell lymphoma of leg type successfully treated by hyperthermic isolated limb perfusion with melphalan. Preoperative regimens included systemic chemotherapy and irradiation. Results: An isolated limb perfusion was performed (100 mg of melphalan, heating 38.5°, cannulation of the superficial femoral artery). One year after the operation a complete response of the disease could be observed. Conclusion: Regional treatment by hyperthermic isolated limb perfusion with melphalan does lead to local tumor control in relapsed cutaneous lymphoma of the extremities. Therefore, ILP should be considered as a possible alternative treatment in selected cases of chemotherapy resistant PCLBCL-LT.
{"title":"Successful Treatment of a Progressive Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Leg (PCLBCL-LT) with Hyperthermic Isolated Limb Perfusion","authors":"I. Karampinis, Laura Schwarzwaelder, M. Hoffmann, T. Gaiser, K. Nowak, P. Hohenberger, J. Jakob","doi":"10.4172/2324-9110.1000207","DOIUrl":"https://doi.org/10.4172/2324-9110.1000207","url":null,"abstract":"Purpose: Hyperthermic isolated limb perfusion (ILP) is a highly effective treatment option for locally advanced soft tissue sarcoma and in-transit metastasized malignant melanoma of the extremities. The role of the hyperthermic isolated limb perfusion in the treatment of aggressive cutaneous b-cell lymphoma (PCLBCL-LT) is unknown. \u0000Methods: This is a case presentation of a 65 year old woman with a multifocal recurrence of a cutaneous b-cell lymphoma of leg type successfully treated by hyperthermic isolated limb perfusion with melphalan. Preoperative regimens included systemic chemotherapy and irradiation. \u0000Results: An isolated limb perfusion was performed (100 mg of melphalan, heating 38.5°, cannulation of the superficial femoral artery). One year after the operation a complete response of the disease could be observed. \u0000Conclusion: Regional treatment by hyperthermic isolated limb perfusion with melphalan does lead to local tumor control in relapsed cutaneous lymphoma of the extremities. Therefore, ILP should be considered as a possible alternative treatment in selected cases of chemotherapy resistant PCLBCL-LT.","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42419191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：