首页 > 最新文献

Accident Analysis & Prevention最新文献

英文 中文
Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes 百里香、芹菜和盐霉素对妊娠巴尔基母羊抗氧化能力和产奶量相关神经递质的影响
Pub Date : 2021-05-31 DOI: 10.11648/J.AAP.20210601.14
S. Eid, O. Ahmed-Farid, H. M. El-Zaher, M. Shabaan
The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P 0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.
本实验旨在探讨百里香(T)、芹菜(C)和盐霉素对巴尔基母羊免疫反应和产奶量相关神经递质的影响。72只成熟母羊(2 ~ 3岁,体重40±1.5 Kg)随机分为5组。第一组为对照组;2组和3组分别给予20g/头/天的T和C。4组给予T 10g + C 10g /头/天,5组给予盐霉素1g/头/天。在妊娠第2、3个月和分娩当天采集的样本;在产后15、30和45天评估产奶量。T和/或C和盐霉素升高(p0.05)。妊娠后期,百里香和/或芹菜组5-HT、DA、NE和Trp升高(P<0.05)。而在DD组,盐霉素增加了神经递质(P<0.05),其他组的增加不显著。T组和/或C组产奶量在产后15、30和45 d显著高于对照组和盐霉素组(P<0.05)。综上所述,各处理对母羊妊娠期和DD期的繁殖性能、免疫应答以及产后产奶量均有显著影响。
{"title":"Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes","authors":"S. Eid, O. Ahmed-Farid, H. M. El-Zaher, M. Shabaan","doi":"10.11648/J.AAP.20210601.14","DOIUrl":"https://doi.org/10.11648/J.AAP.20210601.14","url":null,"abstract":"The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P 0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"256 1","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77535459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studying Resistance of Some Dairy Cattle Breeds to Heat Stress in Relation to Milk Yield 一些奶牛品种耐热性与产奶量的关系研究
Pub Date : 2021-05-14 DOI: 10.11648/J.AAP.20210601.13
A. Gad, S. Emara, S. Eid, H. El-Zaher
The objective for our work was to estimate the milk yield and blood biochemical constituents of and weight daily gain of calves recently born from imported cows under hot summer conditions in Egypt. Thirty late- pregnant cows, aged 22-24 months, chosen randomly were used in this study. Experiment was carried out during the period from third stage of pregnancy and continued to 8 weeks postpartum. Imported late-pregnant cows divided into three groups, each group was 10 cows. 1st group was Brown Swiss (BS) cows, 2nd group was Simmental (S) cows and 3rd group was Holstein (H). Results showed that H cows have a lowest rectal temperature (RT) and respiration rate (RR) in compare with BS and S cows. Results showed that H cows have a highest daily milk yield while S cows have lowest values. BS and H cows have significantly higher total protein, albumin and urea concentrations than S cows. While, globulin and glucose concentrations were significantly higher in BS than its concentrations in S and H cows, respectively. Total cholesterol, phospholipids and creatinine concentrations showed the lowest values in BS cows as compare with S and H cows. Otherwise, BS cows have the highest triglycerides concentration as compare with H and S cows. About liver function showed the highest activity for AST in S cows and for ALT in H cows as compared of other groups. BS cows have significantly higher T4 and Estradiol17β levels than its levels in S and H cows, respectively. Birth weight of newborn both male and female calves as well as daily body weight gain of calves produced from the three imported cows were not differs Significantly. Two months weight of calves produced from S cows was significantly higher than BS and H cows, respectively. In conclusion, the three imported breed cows appears good resistance to heat stress effects under hot summer conditions in Egypt with extremely resistance for H cows.
我们工作的目的是估计在埃及炎热的夏季条件下,最近由进口奶牛出生的小牛的产奶量、血液生化成分和体重日增重。随机选取30头22 ~ 24月龄的晚期妊娠奶牛进行试验。实验从妊娠第三期开始,一直持续到产后8周。将进口晚孕奶牛分为3组,每组10头。结果表明,H组奶牛的直肠温度(RT)和呼吸速率(RR)均低于BS和S组奶牛。结果表明,H奶牛日产奶量最高,S奶牛日产奶量最低。BS和H奶牛的总蛋白、白蛋白和尿素浓度显著高于S奶牛。而BS组的球蛋白和葡萄糖浓度显著高于S组和H组。BS奶牛的总胆固醇、磷脂和肌酐浓度低于S和H奶牛。另外,BS奶牛的甘油三酯浓度高于H和S奶牛。与其他组相比,S奶牛的谷丙转氨酶活性最高,H奶牛的谷丙转氨酶活性最高。BS奶牛T4和Estradiol17β水平显著高于S和H奶牛。3头进口奶牛的公、母犊牛初生体重及日增重差异不显著。S型奶牛2月龄犊牛体重显著高于BS型和H型奶牛。综上所述,在埃及炎热的夏季条件下,3个进口品种奶牛对热应激效应表现出良好的抵抗能力,其中H奶牛的抵抗能力最强。
{"title":"Studying Resistance of Some Dairy Cattle Breeds to Heat Stress in Relation to Milk Yield","authors":"A. Gad, S. Emara, S. Eid, H. El-Zaher","doi":"10.11648/J.AAP.20210601.13","DOIUrl":"https://doi.org/10.11648/J.AAP.20210601.13","url":null,"abstract":"The objective for our work was to estimate the milk yield and blood biochemical constituents of and weight daily gain of calves recently born from imported cows under hot summer conditions in Egypt. Thirty late- pregnant cows, aged 22-24 months, chosen randomly were used in this study. Experiment was carried out during the period from third stage of pregnancy and continued to 8 weeks postpartum. Imported late-pregnant cows divided into three groups, each group was 10 cows. 1st group was Brown Swiss (BS) cows, 2nd group was Simmental (S) cows and 3rd group was Holstein (H). Results showed that H cows have a lowest rectal temperature (RT) and respiration rate (RR) in compare with BS and S cows. Results showed that H cows have a highest daily milk yield while S cows have lowest values. BS and H cows have significantly higher total protein, albumin and urea concentrations than S cows. While, globulin and glucose concentrations were significantly higher in BS than its concentrations in S and H cows, respectively. Total cholesterol, phospholipids and creatinine concentrations showed the lowest values in BS cows as compare with S and H cows. Otherwise, BS cows have the highest triglycerides concentration as compare with H and S cows. About liver function showed the highest activity for AST in S cows and for ALT in H cows as compared of other groups. BS cows have significantly higher T4 and Estradiol17β levels than its levels in S and H cows, respectively. Birth weight of newborn both male and female calves as well as daily body weight gain of calves produced from the three imported cows were not differs Significantly. Two months weight of calves produced from S cows was significantly higher than BS and H cows, respectively. In conclusion, the three imported breed cows appears good resistance to heat stress effects under hot summer conditions in Egypt with extremely resistance for H cows.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"36 1","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74739327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Search for Quantitative Parameters of Scan Path of Image Viewing by Biologically Motivated Model 基于生物动机模型的图像浏览扫描路径定量参数搜索
Pub Date : 2021-05-08 DOI: 10.11648/J.AAP.20210601.12
Shaposhnikov Dmitry, Podladchikova Lubov, Lazurenko Dmitry, Kiroy Valery
The model of viewing scan path formation to search for quantitative parameters of scan path type is presented. In computer simulations, it was revealed that the structure of artificial scan path (focal or spatial ones) significantly (p<0,05) correlates with the number of return fixations of input window on recently viewed image areas. It was revealed that with the decrease of the coefficient of IOR, the model in most cases forms trajectories of focal type. On the contrary, as the coefficient of the IOR increases, model spatial type trajectories dominated. In addition to differences in the number of return fixations of the input window of the model between focal and spatial trajectories, a trend of differences between the two types of model trajectories in the amplitude of window jumps was found. The model assumption about the possibility of a quantitative characteristic of the trajectory structure based on return fixations is confirmed at processing the results of psychophysical tests of free viewing and search for modified fragments of complex images. It was shown that the number of gaze return fixations is significantly (p<0,05) higher in tests of free image viewing compared to search tests. The results obtained allow us to consider the probability of return fixations as a quantitative criterion to determine of scan path type.
提出了通过观察扫描路径形成来搜索扫描路径类型定量参数的模型。在计算机模拟中,我们发现人工扫描路径的结构(焦点路径或空间路径)与输入窗口在最近查看的图像区域的返回注视次数显著相关(p< 0.05)。结果表明,随着IOR系数的减小,模型在大多数情况下形成焦型轨迹。相反,随着IOR系数的增大,模式空间型轨迹占主导地位。除了焦点轨迹和空间轨迹在模型输入窗口的返回注视次数上存在差异外,两种类型的模型轨迹在窗口跳跃幅度上也存在差异。在处理自由观看和搜索复杂图像修改片段的心理物理测试结果时,证实了基于返回注视的轨迹结构可能具有定量特征的模型假设。结果表明,与搜索测试相比,自由图像观看测试的凝视注视次数显著(p< 0.05)高于搜索测试。所得结果允许我们考虑返回固定的概率作为确定扫描路径类型的定量准则。
{"title":"Search for Quantitative Parameters of Scan Path of Image Viewing by Biologically Motivated Model","authors":"Shaposhnikov Dmitry, Podladchikova Lubov, Lazurenko Dmitry, Kiroy Valery","doi":"10.11648/J.AAP.20210601.12","DOIUrl":"https://doi.org/10.11648/J.AAP.20210601.12","url":null,"abstract":"The model of viewing scan path formation to search for quantitative parameters of scan path type is presented. In computer simulations, it was revealed that the structure of artificial scan path (focal or spatial ones) significantly (p<0,05) correlates with the number of return fixations of input window on recently viewed image areas. It was revealed that with the decrease of the coefficient of IOR, the model in most cases forms trajectories of focal type. On the contrary, as the coefficient of the IOR increases, model spatial type trajectories dominated. In addition to differences in the number of return fixations of the input window of the model between focal and spatial trajectories, a trend of differences between the two types of model trajectories in the amplitude of window jumps was found. The model assumption about the possibility of a quantitative characteristic of the trajectory structure based on return fixations is confirmed at processing the results of psychophysical tests of free viewing and search for modified fragments of complex images. It was shown that the number of gaze return fixations is significantly (p<0,05) higher in tests of free image viewing compared to search tests. The results obtained allow us to consider the probability of return fixations as a quantitative criterion to determine of scan path type.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"146 1","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2021-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80542835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Possible Way to Improve the Quality of Speech Perception by Increasing the Number of Electrodes in a Cochlear Implant from 8 to 22 通过将人工耳蜗的电极数量从8个增加到22个来提高语音感知质量的可能方法
Pub Date : 2020-12-31 DOI: 10.11648/J.AAP.20200502.18
Margarita Stefanovich
A cochlear implant (CI) helps a person with auditory receptor pathology restore the ability to hear and understand speech. The partial loss of the information about the frequency and loudness of the audio signal is the main difference from the natural sound perception. CIs of various types differ in the number of stimulated electrodes: 12, 16, 20, or 22. The quality of speech perception is significantly improved by increasing the number of stimulated electrodes from 4 to 7 and almost does not change with a further increase in the number of electrodes from 8 to 22. When speech is perceived in all types of CI, 3 to 6 adjacent electrodes are usually stimulated simultaneously. When a single electrode is stimulated, the CI user hears a sound with a single pitch. When two adjacent electrodes E(n) and E(n+1) are simultaneously stimulated, a virtual frequency channel (VFC) is formed, and the CI user hears a sound with an intermediate pitch {Z(n)+Z(n+1)}/2, provided that the adjacent electrodes on the right and left are not stimulated. When three or more adjacent electrodes are simultaneously stimulated, the CI user hears a sound with the same pitch, which depends on the distance from the electrode with the largest amplitude of stimulating pulses to the apex of the cochlea. There was no suggestion as to why the quality of speech perception does not improve when the number of electrodes increases from 8 to 22 in the scientific literature for the period from 1997 to 2019. This article proposes a method for adjusting the mode electrodes stimulation, which creates conditions for the formation of virtual frequency channels. The CI user will be able to hear a greater number of sounds of various pitch. A method for correcting the algorithm for controlling the stimulation of electrodes, which can be used in any type of CI, is proposed.
人工耳蜗(CI)可以帮助患有听觉受体病变的人恢复听和理解语言的能力。音频信号的频率和响度信息的部分丢失是与自然声音感知的主要区别。不同类型的CIs的受激电极数量不同:12、16、20或22。当刺激电极的数量从4个增加到7个时,语音感知的质量得到了显著的提高,并且当刺激电极的数量从8个增加到22个时,语音感知的质量几乎没有变化。当在所有类型的CI中感知语音时,通常同时刺激3至6个相邻电极。当单个电极受到刺激时,CI用户会听到具有单一音调的声音。当相邻两个电极E(n)和E(n+1)同时受到刺激时,形成一个虚拟频率通道(VFC), CI用户听到的声音为中间音高{Z(n)+Z(n+1)}/2,前提是左右相邻电极不受刺激。当三个或更多相邻电极同时受到刺激时,CI使用者听到的声音具有相同的音高,这取决于刺激脉冲振幅最大的电极到耳蜗顶点的距离。在1997年至2019年的科学文献中,没有任何迹象表明,当电极数量从8个增加到22个时,语音感知的质量没有得到改善。本文提出了一种调节模式电极刺激的方法,为虚拟频率通道的形成创造了条件。CI用户将能够听到更多不同音高的声音。提出了一种校正控制电极刺激算法的方法,该方法可用于任何类型的CI。
{"title":"A Possible Way to Improve the Quality of Speech Perception by Increasing the Number of Electrodes in a Cochlear Implant from 8 to 22","authors":"Margarita Stefanovich","doi":"10.11648/J.AAP.20200502.18","DOIUrl":"https://doi.org/10.11648/J.AAP.20200502.18","url":null,"abstract":"A cochlear implant (CI) helps a person with auditory receptor pathology restore the ability to hear and understand speech. The partial loss of the information about the frequency and loudness of the audio signal is the main difference from the natural sound perception. CIs of various types differ in the number of stimulated electrodes: 12, 16, 20, or 22. The quality of speech perception is significantly improved by increasing the number of stimulated electrodes from 4 to 7 and almost does not change with a further increase in the number of electrodes from 8 to 22. When speech is perceived in all types of CI, 3 to 6 adjacent electrodes are usually stimulated simultaneously. When a single electrode is stimulated, the CI user hears a sound with a single pitch. When two adjacent electrodes E(n) and E(n+1) are simultaneously stimulated, a virtual frequency channel (VFC) is formed, and the CI user hears a sound with an intermediate pitch {Z(n)+Z(n+1)}/2, provided that the adjacent electrodes on the right and left are not stimulated. When three or more adjacent electrodes are simultaneously stimulated, the CI user hears a sound with the same pitch, which depends on the distance from the electrode with the largest amplitude of stimulating pulses to the apex of the cochlea. There was no suggestion as to why the quality of speech perception does not improve when the number of electrodes increases from 8 to 22 in the scientific literature for the period from 1997 to 2019. This article proposes a method for adjusting the mode electrodes stimulation, which creates conditions for the formation of virtual frequency channels. The CI user will be able to hear a greater number of sounds of various pitch. A method for correcting the algorithm for controlling the stimulation of electrodes, which can be used in any type of CI, is proposed.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"15 1","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72908504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Royal Jelly Supplement on Ewe's Milk Fat Content and Fatty Acid Profile During the Early Stage of Lactation 添加蜂王浆对哺乳期早期母羊乳脂含量和脂肪酸分布的影响
Pub Date : 2020-10-21 DOI: 10.11648/J.AAP.20200502.15
A. A. El-Tarabany, O. Ahmed-Farid, S. Emara, M. S. El-Tarabany
The aim was to study the possible effects of royal jelly (RJ) supplementation on milk fat content and fatty acids (FA) profile of ewes during the early stage of lactation. Randomly, thirty-six Ossimi ewes were divided into two groups (18 animals each). The first group was offered the basal diet which was considered as a control group, whereas the second group was fed the basal diet, in addition to a supplement of a single bolus of RJ (1000 mg/head) every two days as a treated group. Regardless the effect of time, the RJ-supplemented group recorded a non-significant increase in daily milk yield (1.22 kg) when compared with the control (1.08 kg) group (P<0.063). While, the RJ-supplemented ewes showed significantly increase in milk fat percentage (P<0.008) as compared to control group. Lactating ewes in the control group produced significantly higher contents of milk C14:0 (P<0.036) and C18:0 (P<0.027) saturated FA than that in the RJ group. However, the contents of milk C6:0 and C17:0 in the RJ group were significantly greater than that estimated in the control (P<0.050 and 0.041, respectively). Furthermore, Lactating ewes supplemented with RJ produced significantly higher contents of milk C16:1 (P<0.001), C18:1 (P<0.001) and C18:2 (P<0.046) unsaturated FA than the control group. It can be concluded that supplementation of ewes during the early stage of lactation with RJ can improve the nutritive value of milk fat, and appears to be an opportunity to modify the concentrations of certain milk fatty acids.
本试验旨在研究添加蜂王浆对泌乳期早期母羊乳脂含量和脂肪酸谱的可能影响。将36只奥西米母羊随机分为两组(每组18只)。第1组饲喂基础饲粮作为对照组,第2组在基础饲粮基础上每2天添加1个RJ (1000 mg/头)作为治疗组。不考虑时间的影响,与对照组(1.08 kg)相比,rj添加组的日产奶量(1.22 kg)无显著增加(P<0.063)。与对照组相比,添加rj的母羊的乳脂率显著提高(P<0.008)。对照组泌乳母羊产奶C14:0 (P<0.036)和C18:0 (P<0.027)饱和脂肪酸含量显著高于RJ组。RJ组乳汁C6:0和C17:0含量显著高于对照组(P分别<0.050和0.041)。此外,添加RJ的泌乳母羊的乳汁C16:1 (P<0.001)、C18:1 (P<0.001)和C18:2 (P<0.046)不饱和脂肪酸含量显著高于对照组。由此可见,泌乳期早期在母羊饲粮中添加RJ可提高乳脂的营养价值,并有可能改变乳中某些脂肪酸的浓度。
{"title":"Impact of Royal Jelly Supplement on Ewe's Milk Fat Content and Fatty Acid Profile During the Early Stage of Lactation","authors":"A. A. El-Tarabany, O. Ahmed-Farid, S. Emara, M. S. El-Tarabany","doi":"10.11648/J.AAP.20200502.15","DOIUrl":"https://doi.org/10.11648/J.AAP.20200502.15","url":null,"abstract":"The aim was to study the possible effects of royal jelly (RJ) supplementation on milk fat content and fatty acids (FA) profile of ewes during the early stage of lactation. Randomly, thirty-six Ossimi ewes were divided into two groups (18 animals each). The first group was offered the basal diet which was considered as a control group, whereas the second group was fed the basal diet, in addition to a supplement of a single bolus of RJ (1000 mg/head) every two days as a treated group. Regardless the effect of time, the RJ-supplemented group recorded a non-significant increase in daily milk yield (1.22 kg) when compared with the control (1.08 kg) group (P<0.063). While, the RJ-supplemented ewes showed significantly increase in milk fat percentage (P<0.008) as compared to control group. Lactating ewes in the control group produced significantly higher contents of milk C14:0 (P<0.036) and C18:0 (P<0.027) saturated FA than that in the RJ group. However, the contents of milk C6:0 and C17:0 in the RJ group were significantly greater than that estimated in the control (P<0.050 and 0.041, respectively). Furthermore, Lactating ewes supplemented with RJ produced significantly higher contents of milk C16:1 (P<0.001), C18:1 (P<0.001) and C18:2 (P<0.046) unsaturated FA than the control group. It can be concluded that supplementation of ewes during the early stage of lactation with RJ can improve the nutritive value of milk fat, and appears to be an opportunity to modify the concentrations of certain milk fatty acids.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"28 1","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90717967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subjective vs. Objective Urine Color: Effect of Hydration Status 主观与客观尿色:水合状态的影响
Pub Date : 2020-09-04 DOI: 10.11648/J.AAP.20200502.12
Tory A. Edwards, R. Belasco, Alfonso Joaquin Munoz, V. Rayo, M. Buono
Purpose: To investigate the validity of urine color as a metric of hydration status using CIE L*a*b* color space, as compared to the commonly used subjective 8-point scale. Methods: A total of 151 urine samples were collected from subjects (N=28) in various states of hydration. Urine osmolality and urine specific gravity (USG) were measured in each sample. Urine color was assessed by the subjective 8-point urine color scale and quantified using CIE L*a*b* color space. RESULTS: The correlation between the CIE b*-value and urine osmolality (rs=0.89) was determined to be significantly (p=0.004) greater than the correlation between the subjective 8-point urine color scale and urine osmolality (rs=0.85). The correlation between the CIE b*-value and USG (rs=0.90) was also determined to be significantly (p < 0.001) greater than the correlation between the urine color chart and USG (rs=0.84). Lastly, the correlation between urine color as determined by the 8-point subjective urine color chart and the CIE b*-value had a strong relationship (rs=0.92). Conclusions: The correlations of the quantitative CIE b*-value with urine osmolality and USG were significantly greater than the correlations with the 8-point subjective urine color scale. This suggests that a quantitative measurement of urine color via spectrophotometry is a better measure for assessing hydration status vs. subjective determination of urine color. The results of the current study raise the possibility of spectrophotometry as an additional non-invasive method of determining hydration status.
目的:与常用的主观8分制相比,利用CIE L*a*b*颜色空间研究尿液颜色作为水合状态度量的有效性。方法:采集28例不同水合状态下的尿样151份。测定每个样品的尿渗透压和尿比重(USG)。尿液颜色采用主观8点尿液颜色量表进行评估,并使用CIE L*a*b*颜色空间进行量化。结果:CIE b*值与尿渗透压的相关性(rs=0.89)显著(p=0.004)大于主观8点尿色标与尿渗透压的相关性(rs=0.85)。CIE b*值与USG的相关性(rs=0.90)也被确定为显著(p < 0.001)大于尿液颜色图与USG的相关性(rs=0.84)。最后,由8点主观尿色图确定的尿色与CIE b*值之间存在很强的相关性(rs=0.92)。结论:定量CIE b*值与尿渗透压和USG的相关性显著大于与8点主观尿色量表的相关性。这表明,通过分光光度法定量测量尿液颜色与主观测定尿液颜色相比,是评估水合状态的更好方法。目前的研究结果提高了分光光度法作为测定水合状态的一种非侵入性方法的可能性。
{"title":"Subjective vs. Objective Urine Color: Effect of Hydration Status","authors":"Tory A. Edwards, R. Belasco, Alfonso Joaquin Munoz, V. Rayo, M. Buono","doi":"10.11648/J.AAP.20200502.12","DOIUrl":"https://doi.org/10.11648/J.AAP.20200502.12","url":null,"abstract":"Purpose: To investigate the validity of urine color as a metric of hydration status using CIE L*a*b* color space, as compared to the commonly used subjective 8-point scale. Methods: A total of 151 urine samples were collected from subjects (N=28) in various states of hydration. Urine osmolality and urine specific gravity (USG) were measured in each sample. Urine color was assessed by the subjective 8-point urine color scale and quantified using CIE L*a*b* color space. RESULTS: The correlation between the CIE b*-value and urine osmolality (rs=0.89) was determined to be significantly (p=0.004) greater than the correlation between the subjective 8-point urine color scale and urine osmolality (rs=0.85). The correlation between the CIE b*-value and USG (rs=0.90) was also determined to be significantly (p < 0.001) greater than the correlation between the urine color chart and USG (rs=0.84). Lastly, the correlation between urine color as determined by the 8-point subjective urine color chart and the CIE b*-value had a strong relationship (rs=0.92). Conclusions: The correlations of the quantitative CIE b*-value with urine osmolality and USG were significantly greater than the correlations with the 8-point subjective urine color scale. This suggests that a quantitative measurement of urine color via spectrophotometry is a better measure for assessing hydration status vs. subjective determination of urine color. The results of the current study raise the possibility of spectrophotometry as an additional non-invasive method of determining hydration status.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"78 1","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84656496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Beneficial Effects of Yoga on Memory and Cognition Associated to Stress 瑜伽对与压力相关的记忆和认知的有益影响
Pub Date : 2020-07-14 DOI: 10.11648/J.AAP.20200502.11
S. Mitra, Mousumi Mitra, M. Saha, D. Nandi
Stress generally occurs due to the organism’s non-specific response against some kind of demand imposed on them. The compensatory responses to these stresses are known as stress response. The stressful stimuli can advance the physiological and psychological effects on the body which includes executive functions of the brain. The prefrontal cortex shows an important connection between the circuits that are linked with emotions, memory and planning. Due to this activation of stressful condition or situation damage occurs in the prefrontal cortex because of the catecholaminergic nature of its innervating afferents in the other parts of the brain. Along with hippocampus, the amygdala and prefrontal cortex define the aspects of memory and visual processing within brain. The decrease in PNS and GABAergic activity that causes stress related disorders can be corrected by yoga practice resulting in amelioration of disease system in the brain such as reduction in anxiety and improvement in cognitive function. Depression, Post Traumatic Stress Disorder (PTSD) that are elevated by stress shows low heart rate variability (HRV) and GABAergic activity which can be improved in response to yoga based interventions. Yoga practices show increase in the proportion of gray matter and escalation in activation of amygdala and frontal cortex of the brain. It was concluded that breathing, meditation and posture based yoga increased overall brain function and activity.
压力通常是由于生物体对强加给它们的某种需求的非特异性反应而产生的。对这些压力的补偿反应被称为应激反应。压力刺激可以促进身体的生理和心理影响,其中包括大脑的执行功能。前额叶皮层显示了与情绪、记忆和计划有关的回路之间的重要联系。由于这种应激状态或情境的激活,前额叶皮层由于其在大脑其他部分的神经支配传入的儿茶酚胺能性质而发生损伤。与海马体一样,杏仁核和前额叶皮层决定了大脑中记忆和视觉处理的各个方面。导致压力相关疾病的PNS和gaba能活动的减少可以通过瑜伽练习得到纠正,从而改善大脑疾病系统,如减少焦虑和改善认知功能。因压力而升高的抑郁症、创伤后应激障碍(PTSD)表现出较低的心率变异性(HRV)和gaba能活动,这可以通过瑜伽干预得到改善。瑜伽练习可以增加大脑灰质的比例,增加杏仁核和额叶皮层的激活。研究得出的结论是,呼吸、冥想和基于姿势的瑜伽可以提高大脑的整体功能和活动。
{"title":"Beneficial Effects of Yoga on Memory and Cognition Associated to Stress","authors":"S. Mitra, Mousumi Mitra, M. Saha, D. Nandi","doi":"10.11648/J.AAP.20200502.11","DOIUrl":"https://doi.org/10.11648/J.AAP.20200502.11","url":null,"abstract":"Stress generally occurs due to the organism’s non-specific response against some kind of demand imposed on them. The compensatory responses to these stresses are known as stress response. The stressful stimuli can advance the physiological and psychological effects on the body which includes executive functions of the brain. The prefrontal cortex shows an important connection between the circuits that are linked with emotions, memory and planning. Due to this activation of stressful condition or situation damage occurs in the prefrontal cortex because of the catecholaminergic nature of its innervating afferents in the other parts of the brain. Along with hippocampus, the amygdala and prefrontal cortex define the aspects of memory and visual processing within brain. The decrease in PNS and GABAergic activity that causes stress related disorders can be corrected by yoga practice resulting in amelioration of disease system in the brain such as reduction in anxiety and improvement in cognitive function. Depression, Post Traumatic Stress Disorder (PTSD) that are elevated by stress shows low heart rate variability (HRV) and GABAergic activity which can be improved in response to yoga based interventions. Yoga practices show increase in the proportion of gray matter and escalation in activation of amygdala and frontal cortex of the brain. It was concluded that breathing, meditation and posture based yoga increased overall brain function and activity.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"51 1","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84009622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Blue and Red Light on Wheat Leaves 蓝光和红光对小麦叶片的影响
Pub Date : 2020-05-19 DOI: 10.11648/J.AAP.20200501.12
Azizov Ibrahim Vahab, Gasymova Fazile Imtu, Ibrahimova Ulker Faik, Tagiyeva Kenul Rafik, Abdullayeva Asmar Bahruz
The effect of blue and red light on the activity of catalase and ascorbate peroxidase, the content of proteins and soluble carbohydrates in the leaves of wheat varieties under the action of sodium chloride was investigated. The objects of the research were bread wheat Saratovskaya-29 (Triticum aestivum L.) and durum wheat Barakatli-95 (Triticum durum Desf.). Plants were grown in laboratory conditions in an aqueous medium using a Knoop nutrient medium. Experimental plants were coated with transparent films transmitting light at wavelengths of 420-480 nm (blue light) and 640-680 nm (red light). During the growing season, samples of fully formed leaves were taken for physiological and biochemical studies every week at 11 a. m. Under the action of sodium chloride, the accumulation of hydrogen peroxide in white light was higher than in blue and red light. Low catalase activity also observed in blue and red light under the action of sodium chloride in both varieties. In the bread wheat variety Saratovskaya -29 the level of hydrogen peroxide, the activity of catalase and ascorbate peroxidase enzymes were lower than those of the Barakatli-95 durum wheat variety. Blue light stimulated the synthesis of proteins, while red light stimulated the synthesis of carbohydrates. Blue and red light prevented the formation of H2O2 under the action of NaCl.
研究了蓝光和红光对氯化钠作用下小麦品种叶片过氧化氢酶和抗坏血酸过氧化物酶活性、蛋白质和可溶性碳水化合物含量的影响。以面包小麦Saratovskaya-29 (Triticum aestivum L.)和硬粒小麦Barakatli-95 (Triticum durum Desf.)为研究对象。植物在实验室条件下使用努普营养培养基在水培养基中生长。实验植物涂上透明薄膜,透射波长为420-480 nm(蓝光)和640-680 nm(红光)。在生长季节,每周上午11点采集完全成形叶片进行生理生化研究。在氯化钠作用下,白光下过氧化氢的积累量高于蓝光和红光。在氯化钠作用下,两个品种在蓝光和红光下过氧化氢酶活性均较低。面包小麦品种Saratovskaya -29的过氧化氢水平、过氧化氢酶和抗坏血酸过氧化物酶活性低于Barakatli-95硬粒小麦品种。蓝光刺激蛋白质的合成,红光刺激碳水化合物的合成。蓝光和红光抑制了NaCl作用下H2O2的生成。
{"title":"Impact of Blue and Red Light on Wheat Leaves","authors":"Azizov Ibrahim Vahab, Gasymova Fazile Imtu, Ibrahimova Ulker Faik, Tagiyeva Kenul Rafik, Abdullayeva Asmar Bahruz","doi":"10.11648/J.AAP.20200501.12","DOIUrl":"https://doi.org/10.11648/J.AAP.20200501.12","url":null,"abstract":"The effect of blue and red light on the activity of catalase and ascorbate peroxidase, the content of proteins and soluble carbohydrates in the leaves of wheat varieties under the action of sodium chloride was investigated. The objects of the research were bread wheat Saratovskaya-29 (Triticum aestivum L.) and durum wheat Barakatli-95 (Triticum durum Desf.). Plants were grown in laboratory conditions in an aqueous medium using a Knoop nutrient medium. Experimental plants were coated with transparent films transmitting light at wavelengths of 420-480 nm (blue light) and 640-680 nm (red light). During the growing season, samples of fully formed leaves were taken for physiological and biochemical studies every week at 11 a. m. Under the action of sodium chloride, the accumulation of hydrogen peroxide in white light was higher than in blue and red light. Low catalase activity also observed in blue and red light under the action of sodium chloride in both varieties. In the bread wheat variety Saratovskaya -29 the level of hydrogen peroxide, the activity of catalase and ascorbate peroxidase enzymes were lower than those of the Barakatli-95 durum wheat variety. Blue light stimulated the synthesis of proteins, while red light stimulated the synthesis of carbohydrates. Blue and red light prevented the formation of H2O2 under the action of NaCl.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"11 1","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2020-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73636631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malaria Parasitaemia and Changes in Follicle Stimulating Hormone and Luteinizing Hormone Levels of Adult Mice 疟疾寄生虫病与成年小鼠促卵泡激素和黄体生成素水平的变化
Pub Date : 2020-04-14 DOI: 10.11648/J.AAP.20200501.11
N. Obidike, Ebite Lilian Ozokor, O. Irikefe, Gbagbeke Kelvin Obakore, Kelechi Keneth Anachuna
To understand the treatment of malaria, it is important to understand the effect of the administration of specific anti-malarials on various physiological variables. Current study investigated the effect (s) of the anti-malarial, coartem and co-administration of the antioxidant, Vitamin E on the levels of Luteinising and Follicle Stimulating Hormones [LH and FSH] of malaria parasite infected mice. Twenty-eight (28) adult mice were obtained, acclimatized for two (2) weeks and randomly selected into four (4) groups of seven (7) rats per group. Group 1 (Control) received standard mice diet and water ad libitum, while group 2 mice were infected with malaria (Plasmodium berghei) and left untreated. Groups 3 and 4 were inoculated with malaria (Plasmodium berghei); then treated with coartem and coartem + vitamin E respectively. After three (3) weeks of administration of test substance, the mice blood samples were obtained from mice (for each group) and assayed for serum FSH and LH levels. Statistical comparison was then conducted (using the student t-test) against those of control group to ascertain the effects of the changes due to coartem and/or antioxidant vitamin E co-administration to plasmodium berghei infected mice. Study found a statistically significant increase in serum LH levels of male mice after inoculation with plasmodium berghei. This decrease was noticed more even with coartem and antioxidant vitamin E co-administration, implicative of a possible effect in fecundity levels of infected male mice. The level of FSH was significantly increased in infected mice, but however showed a reversal following treatment with coartem and/or antioxidant vitamin E. The effects on reproductive hormones seen here may mirror the effects in man. More studies are needed to elucidate that.
为了了解疟疾的治疗,了解特定抗疟疾药物对各种生理变量的影响是很重要的。目前的研究调查了抗疟药复方蒿甲醚和抗氧化剂维生素E对疟疾寄生虫感染小鼠黄体生成素和促卵泡激素[LH和FSH]水平的影响。取成年小鼠28只,驯化2周后随机分为4组,每组7只。1组(对照组)给予标准小鼠饮食和随意饮水,2组小鼠感染疟疾(伯氏疟原虫),不进行治疗。第3组和第4组接种疟疾(伯氏疟原虫);分别给予复方蒿甲醚和复方蒿甲醚+维生素E处理。给药三(3)周后,取各组小鼠血样,测定血清FSH和LH水平。然后与对照组进行统计比较(使用学生t检验),以确定复方蒿甲醚和/或抗氧化维生素E共同给药对伯氏疟原虫感染小鼠的影响。研究发现,接种伯氏疟原虫后,雄性小鼠血清LH水平有统计学意义的升高。即使在复方蒿甲醚和抗氧化剂维生素E共同施用时,这种下降也更为明显,这暗示了对受感染雄性小鼠的繁殖水平可能产生的影响。感染小鼠的卵泡刺激素水平显著升高,但在用复方蒿甲醚和/或抗氧化维生素e治疗后出现逆转。这里看到的对生殖激素的影响可能反映了人类的影响。需要更多的研究来阐明这一点。
{"title":"Malaria Parasitaemia and Changes in Follicle Stimulating Hormone and Luteinizing Hormone Levels of Adult Mice","authors":"N. Obidike, Ebite Lilian Ozokor, O. Irikefe, Gbagbeke Kelvin Obakore, Kelechi Keneth Anachuna","doi":"10.11648/J.AAP.20200501.11","DOIUrl":"https://doi.org/10.11648/J.AAP.20200501.11","url":null,"abstract":"To understand the treatment of malaria, it is important to understand the effect of the administration of specific anti-malarials on various physiological variables. Current study investigated the effect (s) of the anti-malarial, coartem and co-administration of the antioxidant, Vitamin E on the levels of Luteinising and Follicle Stimulating Hormones [LH and FSH] of malaria parasite infected mice. Twenty-eight (28) adult mice were obtained, acclimatized for two (2) weeks and randomly selected into four (4) groups of seven (7) rats per group. Group 1 (Control) received standard mice diet and water ad libitum, while group 2 mice were infected with malaria (Plasmodium berghei) and left untreated. Groups 3 and 4 were inoculated with malaria (Plasmodium berghei); then treated with coartem and coartem + vitamin E respectively. After three (3) weeks of administration of test substance, the mice blood samples were obtained from mice (for each group) and assayed for serum FSH and LH levels. Statistical comparison was then conducted (using the student t-test) against those of control group to ascertain the effects of the changes due to coartem and/or antioxidant vitamin E co-administration to plasmodium berghei infected mice. Study found a statistically significant increase in serum LH levels of male mice after inoculation with plasmodium berghei. This decrease was noticed more even with coartem and antioxidant vitamin E co-administration, implicative of a possible effect in fecundity levels of infected male mice. The level of FSH was significantly increased in infected mice, but however showed a reversal following treatment with coartem and/or antioxidant vitamin E. The effects on reproductive hormones seen here may mirror the effects in man. More studies are needed to elucidate that.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"95 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2020-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78162055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Ras Oncogene Mutations in Acute Myeloid Leukemia Patients: A Meta-analysis Based on 2502 Cases Ras癌基因突变在急性髓系白血病患者中的作用:基于2502例病例的荟萃分析
Pub Date : 2019-02-18 DOI: 10.11648/J.AAP.20180302.11
Si Li, Peng-bo Zhang, Yong Zhang, Li Wang
Background: the ras oncogene mutations frequently occurred in acute myeloid leukemia (AML), but as a prognostic factor remains inconclusive. Methods: The databases of PubMed, Web of Science, EMBASE, and the Cochrane. 22 eligible studies were included this study and analysis was conducted by Comprehensive Meta-Analysis Version 2 software program. All eligible study’s quality assessment refers to the European Lung Cancer Party quality scale. Results: Combined analysis showed that ras oncogene mutation was a poor impact on survival in AML patients (Hazard ratios (HRs): 1.50, 1.19-1.89, p <0.001). Nras gene mutation was a worse survival marker in AML (HR: 1.97, 95% CI: 1.35-2.89, p <0.001) and Kras gene mutations was no significance (HR: 1.32, 95% CI: 0.83-2.09, p =0.24) by stratified analysis. In the analysis of age bracket, adults with ras gene mutation had an unfavorable survival (HR: 1.55, 95% CI: 1.19-2.21, p =0.01) and children harbored ras gene mutation was not significantly with prognosis (HR: 1.22, 95% CI: 0.97-1.53, p =0.09) in AML. Conclusions: This study indicated that AML patients was poor prognosis especially in adult group with ras oncogene mutation, in which Nras mutation, but not Kras mutation involved in guiding survival.
背景:ras癌基因突变常见于急性髓系白血病(AML),但其作为预后因素尚无定论。方法:检索PubMed、Web of Science、EMBASE、Cochrane等数据库,纳入22项符合条件的研究,采用第2版综合meta分析软件进行分析。所有符合条件的研究的质量评价参照欧洲肺癌党质量量表。结果:综合分析显示,ras癌基因突变对AML患者的生存影响较小(风险比(hr): 1.50, 1.19-1.89, p <0.001)。分层分析显示,Nras基因突变是AML患者较差的生存标志物(HR: 1.97, 95% CI: 1.35 ~ 2.89, p <0.001), Kras基因突变无显著性(HR: 1.32, 95% CI: 0.83 ~ 2.09, p =0.24)。在年龄组分析中,ras基因突变的成人对急性髓系白血病患者的生存不利(HR: 1.55, 95% CI: 1.19 ~ 2.21, p =0.01), ras基因突变的儿童对预后无显著影响(HR: 1.22, 95% CI: 0.97 ~ 1.53, p =0.09)。结论:本研究提示AML患者预后较差,尤其是ras癌基因突变成年组,其中Nras突变参与指导生存,而Kras突变不参与指导生存。
{"title":"The Role of Ras Oncogene Mutations in Acute Myeloid Leukemia Patients: A Meta-analysis Based on 2502 Cases","authors":"Si Li, Peng-bo Zhang, Yong Zhang, Li Wang","doi":"10.11648/J.AAP.20180302.11","DOIUrl":"https://doi.org/10.11648/J.AAP.20180302.11","url":null,"abstract":"Background: the ras oncogene mutations frequently occurred in acute myeloid leukemia (AML), but as a prognostic factor remains inconclusive. Methods: The databases of PubMed, Web of Science, EMBASE, and the Cochrane. 22 eligible studies were included this study and analysis was conducted by Comprehensive Meta-Analysis Version 2 software program. All eligible study’s quality assessment refers to the European Lung Cancer Party quality scale. Results: Combined analysis showed that ras oncogene mutation was a poor impact on survival in AML patients (Hazard ratios (HRs): 1.50, 1.19-1.89, p <0.001). Nras gene mutation was a worse survival marker in AML (HR: 1.97, 95% CI: 1.35-2.89, p <0.001) and Kras gene mutations was no significance (HR: 1.32, 95% CI: 0.83-2.09, p =0.24) by stratified analysis. In the analysis of age bracket, adults with ras gene mutation had an unfavorable survival (HR: 1.55, 95% CI: 1.19-2.21, p =0.01) and children harbored ras gene mutation was not significantly with prognosis (HR: 1.22, 95% CI: 0.97-1.53, p =0.09) in AML. Conclusions: This study indicated that AML patients was poor prognosis especially in adult group with ras oncogene mutation, in which Nras mutation, but not Kras mutation involved in guiding survival.","PeriodicalId":7392,"journal":{"name":"Accident Analysis & Prevention","volume":"20 1","pages":"44"},"PeriodicalIF":0.0,"publicationDate":"2019-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84048538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Accident Analysis & Prevention
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1