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New treatment for Parkinson's disease. 帕金森病的新疗法。
Pub Date : 2001-03-01 DOI: 10.1088/2058-7058/14/3/6
E. Cartlidge
Parkinson's disease is a common neurological condition that affects many people in old age. Physicists and neurologists have been working together for some time to find an effective treatment for the disease, but until now the only alternative to drug therapy has involved applying a continuous electrical signal to the affected part of the brain. Now Peter Tass of the Institute of Medicine at the Research Centre Julich in Germany has used the methods of nonlinear dynamics to show that the disease could be treated by applying double pulses only occasionally to the brain (P Tass 2001 Europhys. Lett. 53 15). This would result in a less severe treatment of the disease.
帕金森氏症是一种常见的神经系统疾病,影响许多老年人。物理学家和神经学家已经合作了一段时间来寻找治疗这种疾病的有效方法,但到目前为止,药物治疗的唯一替代方案是向大脑受影响的部分施加连续的电信号。现在,德国Julich研究中心医学研究所的Peter Tass使用非线性动力学的方法表明,这种疾病可以通过偶尔对大脑施加双脉冲来治疗(P Tass 2001 Europhys)。左53 15)。这将导致对这种疾病的治疗不那么严厉。
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引用次数: 2
Historical perspectives on health. A historical approach to study of the function and dysfunction of the thyroid gland realised? 关于健康的历史观点。历史的方法来研究功能和功能障碍的甲状腺实现?
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800213
A Olukoga, D Donaldson
a new observation or establishes a new piece of information on account of the fact that he/she is not in a position to view a new idea in total perspective. The context of the whole at any one time can only be seen in the light of current knowledge, combined with the degree of individual awareness of a situation. Newly acquired information may indeed lie dormant for many years before a scientific application is found often in a very different discipline. This accompanying assembly of dates is an attempt to list in a meaningful way milestones in the evolution of knowledge in relation to the thyroid gland. In a task such as this it is, of course, very difficult to identify the name of every author who has contributed to
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引用次数: 0
Alcohol consumption worldwide--and the relationship with cancer. 世界范围内的酒精消费——与癌症的关系。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800205
D Donaldson
the American Institute for Cancer Research (1997) has produced a 670 page book entitled Food, Nutrition and the Prevention of Cancer: a Global Perspective published in Washington, USA, by the American Institute for Cancer Research. In part 111, ’Nutrition, Food and Cancer’, there is a discourse on ’Alcohol’ ,Chapter 5.5, pp. 398-403, which commences by observing that there is no physiological need for alcohol and that it is an addictive drug. There is reference to the variability of alcohol consumption in different parts of the world, ranging from zero or near zero consumption (in low income countries or where there is prohibition) to 10%
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引用次数: 0
Some peoples' psychological experiences of attending a sexual health clinic and having a sexually transmitted infection. 一些人到性健康诊所就诊并感染性传播疾病的心理体验。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800210
H S Holgate, C Longman

This study considers aspects of the experiences of a group of people attending a sexual health clinic and receiving the diagnosis of a sexually transmitted infection (STI). The study was conducted in the form of action research using a qualitative approach. Participants consisted of eight attenders at a sexual health clinic who had been diagnosed with a sexually transmitted infection. Counselling skills and techniques were used throughout semi-structured interviews to explore participants' feelings about these issues. Thematic analysis was used to generate themes of importance to the participants. Some people who had been to a sexual health clinic and received a diagnosis of a sexually transmitted infection were found to experience feelings of anxiety, stigma and isolation. This study is of value to all those working in the field of sexual health with an interest in understanding the issues that are important to the client group.

这项研究考虑了到性健康诊所就诊并接受性传播感染诊断的一群人的经历的各个方面。本研究以行动研究的形式进行,采用定性方法。参与者包括在性健康诊所就诊的8名被诊断患有性传播感染的人。在半结构化的访谈中,我们使用了咨询技巧和技巧来探索参与者对这些问题的感受。主题分析用于生成对参与者重要的主题。一些去过性健康诊所并被诊断为性传播感染的人被发现感到焦虑、耻辱和孤立。这项研究对所有在性健康领域工作的人都有价值,他们有兴趣了解对客户群体重要的问题。
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引用次数: 24
Reform of legislation covering deliberate transmission of infectious disease. 改革有关故意传播传染病的立法。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800203
A Shaw
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引用次数: 0
Health promotion, environmental health and Agenda 21. 促进健康、环境卫生和《21世纪议程》。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800208
A Scriven, S Young

In 1992, at the Rio Earth Summit, many governments, including our own, committed themselves to developing local strategies for sustainable development in the form of Local Agenda 21. Sustainable development is discussed, as is the philosophy and practice of health promotion and environmental health. Common approaches are identified and the links in relation to key areas of activities, strategies, values and principles are outlined. Finally, recommendations are made and conclusions drawn in relation to the overlap between environmental health action, Agenda 21 strategies and health promotion practice.

1992年,在里约地球问题首脑会议上,包括我国在内的许多国家政府承诺以《21世纪地方议程》的形式制定可持续发展的地方战略。讨论了可持续发展,以及促进健康和环境卫生的理念和实践。确定了共同的办法,并概述了与活动、战略、价值和原则的关键领域有关的联系。最后,就环境卫生行动、《21世纪议程》战略和促进健康做法之间的重叠问题提出建议并得出结论。
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引用次数: 2
Re: Sexually transmitted diseases among women in Coventry. 回复:考文垂妇女中的性传播疾病。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800217
I wish to draw attention to the dangerous trend in the usage of ’Essential Oils internally, by oral, rectal and vaginal routes by some Aromatherapists. In an article in your Journal last year, I gave the true definition of Aromatherapy, which must involve the odour of the oils but need not include massage in the therapeutic use. I also pointed out that the use of essential oils internally, as medicines on the continent, is conducted by medically qualified doctors and that encapsulated Peppermint oil is used for irritable bowel syndrome (IBS) and a mixture of encapsulated components are used for treating gallstones and ureteric stones, but these have obviously been tested and licenced as medicines. It seems that many aromatherapists with no medical qualifications and devoid of scientific qualifications are now dispensing treatments using essential oils and discussing this on the Internet. As a consequence there is a growing danger that a serious poisoning if not a fatality, will arise due to this dangerous practice and its perpetuation. This danger is illustrated by several paragraphs which appear in the book by Julia Goodwin entitled &dquo;Natural Babycare&dquo; (published by Ebury Press, 1997) where, for example, it is suggested that infantile colic can be relieved by adding 5-10 drops of chamomile oil three times a day to a little warmed water or milk. Depending on the drop size, the dose could be about 6ml per day, and if the baby has a low body weight, it could amount to a toxic dose (based on the LD50). Furthermore, there are at least three types of chamomile oils on the market, which are from different plants, yielding oils of completely different chemical composition; there is also frequent adulteration of essential oils with various solvents which have included
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引用次数: 0
Burden of illness review of obesity: are the true costs realised? 肥胖的疾病负担回顾:真正的成本意识到了吗?
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800207
A M McIntyre

Obesity can no longer be viewed as merely a cosmetic or social problem, but must be acknowledged as a serious disease, responsible for the premature death and morbidity of millions and for significant expenditure of limited healthcare resources. In addition, there are significant costs to the individual with regard to social status and quality of life. It has been argued that obesity is one of the most important preventable causes of ill health in the UK today. This is especially important when one considers that the incidence of obesity is actually rising, with 13% of men and 16% of women in the UK in 1997 being obese. To begin treating such a disease it is essential to raise awareness of this problem, not only from the associated morbidity and mortality risks that have been well documented, but the socio-economic and psychological costs. This paper reviews the literature available globally, giving some measure of the magnitude of the associated burden of illness.

肥胖不能再仅仅被视为一个美容或社会问题,而必须被视为一种严重的疾病,造成数百万人过早死亡和发病,并造成有限的保健资源的大量支出。此外,个人在社会地位和生活质量方面也要付出重大代价。有人认为,肥胖是当今英国最重要的可预防的不健康原因之一。当人们考虑到肥胖的发病率实际上正在上升时,这一点尤其重要,1997年英国有13%的男性和16%的女性肥胖。要开始治疗这一疾病,就必须提高对这一问题的认识,不仅要注意相关的发病率和死亡率风险,而且要注意社会经济和心理成本。本文回顾了全球现有的文献,给出了相关疾病负担的一些衡量标准。
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引用次数: 27
Albumin: what influences its level in the blood? 白蛋白:什么影响它在血液中的水平?
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800206
D Donaldson
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引用次数: 0
Smoking, diabetes and hyperlipidaemia. 吸烟、糖尿病和高脂血症。
Pub Date : 1998-04-01 DOI: 10.1177/146642409811800209
D P Mikhailidis, J A Papadakis, E S Ganotakis

The epidemiological evidence linking smoking with insulin resistance is considerable. This evidence is even more convincing because there is a dose response relationship between smoking and the risk of non-insulin dependent diabetes (NIDDM). Similarly, there is a time-dependent decrease in risk of NIDDM for those who quit smoking. Insulin resistance (in the form of impaired glucose tolerance, IGT) may precede the development of NIDDM. There is a biochemical basis for the smoking-IGT/NIDDM relationship. Smoking increases the risk of developing diabetic complications like nephropathy, neuropathy and retinopathy Smoking is also an independent risk factor for myocardial infarction and all-cause mortality in NIDDM. Smokers are both insulin resistant and lipid intolerant. Smoking cessation increases circulating high density lipoprotein (HDL) and reduces low density lipoprotein (LDL) levels, despite weight gain. Those providing advice or treatment to improve cardiovascular risk factors should be aware of these smoking-related harmful effects. This is especially true if IGT is underdiagnosed despite the fact that this condition increases the risk of vascular events. Explaining that smoking increases the chance of developing diabetes as well as raising 'blood fat' levels may convince more smokers to quit.

将吸烟与胰岛素抵抗联系起来的流行病学证据相当多。这一证据更有说服力,因为吸烟与非胰岛素依赖型糖尿病(NIDDM)风险之间存在剂量反应关系。同样,戒烟者患NIDDM的风险也会随时间而降低。胰岛素抵抗(以糖耐量受损(IGT)的形式)可能先于NIDDM的发展。吸烟与igt /NIDDM的关系有生物化学基础。吸烟增加了肾病、神经病变和视网膜病变等糖尿病并发症的发生风险,吸烟也是NIDDM患者心肌梗死和全因死亡率的独立危险因素。吸烟者既有胰岛素抵抗又有脂质不耐受。戒烟增加循环高密度脂蛋白(HDL),降低低密度脂蛋白(LDL)水平,尽管体重增加。那些提供建议或治疗以改善心血管危险因素的人应该意识到这些与吸烟有关的有害影响。如果IGT诊断不足,尽管这种情况会增加血管事件的风险,这一点尤其正确。解释说吸烟会增加患糖尿病的机会,并提高“血脂”水平,可能会说服更多的吸烟者戒烟。
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引用次数: 47
期刊
Journal of the Royal Society of Health
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