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[A foreign body discovered incidentally during a tonsillectomy]. [扁桃体切除术中意外发现的异物]。
Pub Date : 2024-01-01
Mohamed Saydi Ag Mohamed Elmehdi Elansari, Boubacary Guindo, Mamadou Diallo, Lassine Dienta, Mariam Sangaré, Harouna Sanogo, Mamadou Sidibé, Moussa Konaté, Diaffé Dramé, Abdoul Wahab Haidara, Kadidiatou Traoré, Aminata Fofana, Abdoulaye Dit Modibo Ganaba, Mariam Maiga, Mohamed Amadou Keita

We report an unusual observation of a child aged 07, who consulted us for a chronic odynophagia rebellious to multiple treatments. It dates back to one year followed by pediatrics under antibiotic therapy and anti-inflammatory in whom the examination found hypertrophy noninflammatory obstructive tonsillar. The last episode would go back a month. The rest of the general exam was unremarkable. An indication for tonsillectomy was made and was performed. We fortuitously find a large fishbone skewered in his right tonsil. The postoperative consequences were simple. With a follow-up of 12 months, the patient is doing well.

我们报告了对一名 07 岁儿童的不寻常观察结果,该儿童因慢性吞咽困难而就诊,多次治疗无效。该病可追溯到一年前,儿科在抗生素治疗和抗炎治疗后,检查发现其扁桃体肥大,为非炎症性阻塞性扁桃体。最后一次发作要追溯到一个月前。其余的一般检查没有异常。扁桃体切除术的指征已制定并实施。我们很幸运地在他的右扁桃体中发现了一根巨大的鱼刺。术后并无大碍。随访 12 个月后,患者情况良好。
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引用次数: 0
[Predictors Of Early Mortality During Hospitalization Of Severe Acute Malnourished Children Aged 0-59 Months At CHU Sourô SANOU, Bobo-Dioulasso]. [博博迪乌拉索 Sourô SANOU 医院 0-59 个月严重急性营养不良儿童住院期间早期死亡率的预测因素]。
Pub Date : 2024-01-01
Bintou Sanogo, Mohammed Kassogué, Ad Bafa Ibrahim Ouattara, Abdel Aziz Baby, Edmond Ouedraogo, Raymond K Cessouma, Saga Alain Ouermi, S Aimée Kissou

Objectives: to study risk factors for mortality in SAM children within the first 72 hours of hospitalization.

Methods: We conducted a retrospective study on data from 0-59-month-old SAM children hospitalized from June 1th, 2016, to May 31th, 2019, at CHUSourô Sanou of Bobo-Dioulasso. A logistic regression was performed to determine risk factors for death. Variables with odds ratio (OR) > 1, and p <0.05 were predictors of death.

Results: Of 646 SAMs included, most were 12-23-month-yearold (34.83%). Death rate was 19.04%. Deep coma [OR :27.2, 95%IC: 9.62-91.1], OAP [OR :16.3, 95%IC: 1.58-383], Signs of in particular low pulse volume [OR :5.45, 95%IC: 1.74-17. 1], cold extremities [OR :4.66, 95%IC: 1.03-20.8], capillary refilling time (CRT) >3seconds [OR :3.55, 95%IC: 1.50-8.27], sepsis[OR :3.39, 95%IC: 1.33-8.50] were the risk factors predictive of mortality.

Conclusion: Training and ongoing supervision of healthcare staff in the management of paediatric emergencies, the use of the WHO SAM management protocol and the availability of emergency kits could improve SAM management.

目的:研究SAM患儿住院72小时内的死亡风险因素:我们对2016年6月1日至2019年5月31日期间在博博迪乌拉索CHUSourô Sanou住院的0-59个月大SAM儿童的数据进行了回顾性研究。为确定死亡风险因素,进行了逻辑回归。比值比(OR)大于 1 的变量和 p 结果:在纳入的 646 名 SAM 中,大多数为 12-23 个月大的儿童(34.83%)。死亡率为 19.04%。深昏迷[OR :27.2, 95%IC: 9.62-91.1]、OAP[OR :16.3, 95%IC: 1.58-383]、特别是脉搏量低的体征[OR :5.45, 95%IC: 1.74-17.1]、四肢冰冷[OR :4.66, 95%IC: 1.03-20.8]、毛细血管再充盈时间(CRT)>3 秒[OR :3.55, 95%IC: 1.50-8.27]、败血症[OR :3.39, 95%IC: 1.33-8.50]是预测死亡率的风险因素:结论:对医护人员进行儿科急症管理方面的培训和持续监督、使用世界卫生组织的 SAM 管理规程以及提供应急包可改善 SAM 管理。
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引用次数: 0
[Anatomy of the axillary fossa: muscular arch of the latissimus dorsi, a trap for axillary curage and breast reconstruction]. [腋窝解剖:背阔肌肌弓,腋窝切除和乳房重建的陷阱]。
Pub Date : 2024-01-01
S Kanté, O I Touré, D Traoré, M Dicko, T B Toure, F Traoré, B Bengaly, S Sanogo, B Bah, A Kanté, A Y Togo, I K Guindo, I Traoré, A Togo, B Togola, N Ongoïba, A K Koumaré

During the dissection of 11 stiffs, we observed the presence of an accessory muscle in the axillary fossa, known as the dorsalis major muscle arch or axillary Carl Langer muscle. This is the main anatomical variation in the walls of the axillary region. This case was reported because of the low frequency of this variation in the axillary region, and the vital importance of incorporating the possible presence of these notions into axillary curage techniques, which may find themselves modified intraoperatively. Ignorance of the dorsalis major muscle arch may be the cause of intra- and postoperative complications during axillary curage or breast reconstruction using a dorsalis major flap.

在解剖 11 例僵直患者的过程中,我们观察到腋窝中存在附属肌肉,即背阔肌弓或腋窝卡尔-朗格肌。这是腋窝壁的主要解剖变异。本病例之所以被报道,是因为这种变异在腋窝区域出现的频率很低,而且将这些可能存在的概念纳入腋窝矫治技术至关重要,因为术中可能会发现自己被修改了。对背阔肌弓的忽视可能是使用背阔肌皮瓣进行腋窝整复或乳房重建时出现术中和术后并发症的原因。
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引用次数: 0
[Polythelia: About A Case And Litterature Review]. [Polythelia:关于一个案例和文学评论]。
Pub Date : 2024-01-01
S A Sanogo, C Sylla, B Diawara, A Adane, A Bocoum, S Fané, I Tegueté, Y Traoré, B T Dembélé, A P Togo, N Mounkoro

Polythelia also known as supernumerary is an anomaly in the breast development by extra number of nipples. We report a case of polythelia in the Gynecology-Obstetrics department of the CHU Gabriel Touré. This was a 32-year-old woman received for pregnancy monitoring, in whom we accidentally discovered three pairs of nipples located on both breasts. In the postpartum period, five of the six nipples were found to secrete milk.

多乳头症又称 "超数乳头症",是一种乳房发育异常,即乳头数量过多。我们报告了加布里埃尔-图埃中央医院妇产科的一例多乳头症病例。这是一名接受妊娠监测的 32 岁女性,我们意外地在她的双侧乳房上发现了三对乳头。在产后,我们发现六个乳头中有五个会分泌乳汁。
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引用次数: 0
[Prevalence Of Mental Disorders And Addictive Behaviours Among Artisanal Gold Miners In Burkina Faso]. [布基纳法索手工开采金矿者中精神障碍和成瘾行为的发生率]。
Pub Date : 2024-01-01
Boubacar Bague, Mahamane Mobarak Salifou Abdou, Konsam Cédric Christel Sawadogo, Nonpokotinbnooma Myriam Benjamine Ouédraogo, Ibrahima Zirobouré Compaoré, Zeinabou Cisse, Kapouné Karfo, Arouna Ouédraogo

Objectives: The objective was to evaluate mental disorders and addictive behaviours in gold miners treated in the psychiatry department of the Yalgado Ouédraogo University Hospital in Burkina Faso.

Patients and methods: This was a descriptive, cross-sectional, and analytical study with retrospective recruitment of 174 patients over a 10-year period from 1 January 2010 to 31 December 2020. Data were analyzed using SPSS 22 software.

Results: The study population was exclusively male and predominantly young, with a mean age of 28.16 +/- 5.79 years. Most patients were single (59.8%) and had a low level of education (58.82%). Acute psychotic disorders (48.85%) and the mental and behavioral disorders related to the use of psychoactive substances (41.38%) were the most common. 78.73% of patients were users of psychoactive substances (PAS). The most used psychoactive substances were tobacco (75.28%), cannabis (62.64%), alcohol (48.27%) and tramadol (32.18%).

Conclusion: The occurrence of mental disorders among gold miners has become a real public health problem in Burkina Faso, given the growing number of gold mining sites throughout the country.

目的:旨在评估布基纳法索亚尔加多-韦德拉奥果大学医院精神病科收治的金矿矿工的精神障碍和成瘾行为:目的是评估在布基纳法索亚尔加多-韦德拉奥果大学医院精神病科接受治疗的金矿矿工的精神障碍和成瘾行为:这是一项描述性、横断面和分析性研究,从 2010 年 1 月 1 日至 2020 年 12 月 31 日的 10 年间回顾性招募了 174 名患者。数据使用 SPSS 22 软件进行分析:研究对象全部为男性,以年轻人为主,平均年龄为 28.16 +/- 5.79 岁。大多数患者为单身(59.8%),受教育程度较低(58.82%)。急性精神障碍(48.85%)和与使用精神活性物质有关的精神和行为障碍(41.38%)最为常见。78.73%的患者使用精神活性物质(PAS)。使用最多的精神活性物质是烟草(75.28%)、大麻(62.64%)、酒精(48.27%)和曲马多(32.18%):结论:由于布基纳法索全国各地的金矿日益增多,金矿矿工中出现的精神障碍已成为一个真正的公共卫生问题。
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引用次数: 0
[Histo-Molecular Profiles Of Male Breast Cancers In Mali]. [马里男性乳腺癌的组织分子特征]。
Pub Date : 2024-01-01
M Keïta, B Coulibaly, T Sissoko, R Maïga, F Guindo, M N Sanogo, M M Keïta, M Diakité, D Samaké, A Sidibé, A Coulibaly, M Touré, H Traoré, A B Diarra, M S Diakité, M Diarra, S A Touré, A K Cissé, S A Sow, A Konaté, C B Traoré, B Kamaté

Introduction: the occurrence of breast cancer in men is an indication for genetic counseling and must be systematically sought. The objective of this work was to describe the histopathological and molecular aspects of human breast cancer.

Material and methods: This was a cross-sectional study with retrospective collection from January 2007 to September 2021, including all cases of male breast cancer diagnosed by histology with immunohistochemical examination. The variables studied were histopathological and molecular. The samples were fixed in 10% formalin and processed using the standard hematoxylin-eosin and immunohistochemistry technique.

Results: A total of 8 cases of male breast cancer were collected. Each case underwent histological and immunohistochemical examination. Age ranged from 8 to 77 years with a mean age of 50.63±20.79. Consultation time of less than 12 months was common with the presence of a breast nodule as the reason. The left breast was as affected as the right breast. Tumor size T3 (5 cm and more) predominated with 3 cases. The nature of the sample received was: 04 biopsies and 04 lumpectomies. Infiltrative carcinoma of non-specific type was common: 7 cases (or 87.5%) with Elston and Ellis grade II in 75% of cases. Luminal A and triple negative were predominant with 3 cases each (37.5%).

Conclusion: Breast cancer is increasingly diagnosed in men at all ages.

导言:男性乳腺癌的发生是遗传咨询的一个指征,必须系统地寻找。这项工作的目的是描述人类乳腺癌的组织病理学和分子方面:这是一项横断面研究,回顾性收集了 2007 年 1 月至 2021 年 9 月期间所有经组织学和免疫组化检查确诊的男性乳腺癌病例。研究变量包括组织病理学和分子学。样本在10%福尔马林中固定,使用标准苏木精-伊红和免疫组化技术进行处理:结果:共收集到 8 例男性乳腺癌病例。结果:共收集到 8 例男性乳腺癌病例,每例都进行了组织学和免疫组化检查。年龄从 8 岁到 77 岁不等,平均年龄为(50.63±20.79)岁。就诊时间少于 12 个月的情况很常见,原因是存在乳腺结节。左侧乳房与右侧乳房同样受到影响。肿瘤大小以 T3(5 厘米及以上)为主,有 3 例。所获样本的性质为:04 例活组织检查和 04 例肿块切除术。非特异性浸润癌很常见:7 例(占 87.5%),75%的病例为埃尔斯顿和埃利斯 II 级。主要为A型和三阴性,各占3例(37.5%):结论:越来越多的男性在各个年龄段被诊断出患有乳腺癌。
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引用次数: 0
[Epidemiology Of Cerebral Malaria At The University Huc Gabriel Toure Before And After The Implementation Of Seasonnal Malaria Chemoprevention In Bamako]. [巴马科 Huc Gabriel Toure 大学在实施季节性疟疾化学预防前后的脑疟疾流行病学]。
Pub Date : 2024-01-01
A K Kone, B Maiga, S Konate, M Coulibaly, M S Sissoko, A Dabo, M A Thera

Aims: Malaria remains a health problem. The objective was to study cerebral malaria (CM) epidemiology before and after the implementation of seasonal malaria chemoprevention (SMC).

Materials and methods: This was a retrospective cross-sectional study carried out from January 01, 2014 to December 31, 2018 in children aged 0 to 15 years hospitalized for CM at the paediatrics' department of CHU Gabriel Touré.

Results: We recorded 1336 cases of CM, 803 boys and 533 girls with a sex ratio of 1.5. CM accounted for 92.1% and 83.5% respectively two years before and three years after the SMC implementation (p = 0.013). The overall lethality was 9.2% varying according to the years of follow up (p = 0.001) The SMC led to decrease of CM frequency of 8.6%.

Conclusion: SMC could have an impact on the expression of severe malaria phenotypes, with an increase of frequency of CM and CM associated with pulmonary oedema, a decrease of the frequency of CM associated with severe anaemia. Prospective studies will enable to understand the increasing case lethality rate observed during SMC period.

目的:疟疾仍然是一个健康问题。目的是研究季节性疟疾化学预防(SMC)实施前后的脑疟疾(CM)流行病学:这是一项回顾性横断面研究,研究时间为2014年1月1日至2018年12月31日,研究对象为在加布里埃尔-图雷中央医院(CHU Gabriel Touré)儿科住院治疗的0至15岁儿童:我们记录了1336例CM病例,其中男孩803例,女孩533例,性别比为1.5。在实施 SMC 的两年前和三年后,CM 发病率分别为 92.1%和 83.5%(P = 0.013)。总死亡率为 9.2%,随随访年份的不同而变化(p = 0.001):SMC对重症疟疾表型的表现有影响,CM和与肺水肿相关的CM发病率增加,与严重贫血相关的CM发病率减少。前瞻性研究将有助于了解在 SMC 期间观察到的病例致死率增加的情况。
{"title":"[Epidemiology Of Cerebral Malaria At The University Huc Gabriel Toure Before And After The Implementation Of Seasonnal Malaria Chemoprevention In Bamako].","authors":"A K Kone, B Maiga, S Konate, M Coulibaly, M S Sissoko, A Dabo, M A Thera","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>Malaria remains a health problem. The objective was to study cerebral malaria (CM) epidemiology before and after the implementation of seasonal malaria chemoprevention (SMC).</p><p><strong>Materials and methods: </strong>This was a retrospective cross-sectional study carried out from January 01, 2014 to December 31, 2018 in children aged 0 to 15 years hospitalized for CM at the paediatrics' department of CHU Gabriel Touré.</p><p><strong>Results: </strong>We recorded 1336 cases of CM, 803 boys and 533 girls with a sex ratio of 1.5. CM accounted for 92.1% and 83.5% respectively two years before and three years after the SMC implementation (p = 0.013). The overall lethality was 9.2% varying according to the years of follow up (p = 0.001) The SMC led to decrease of CM frequency of 8.6%.</p><p><strong>Conclusion: </strong>SMC could have an impact on the expression of severe malaria phenotypes, with an increase of frequency of CM and CM associated with pulmonary oedema, a decrease of the frequency of CM associated with severe anaemia. Prospective studies will enable to understand the increasing case lethality rate observed during SMC period.</p>","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 3","pages":"33-38"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epidemiological Profile Of Occupational Accidents Occurring In 2022 In A Cashew Nut Processing Plant In Côte d'Ivoire]. [科特迪瓦腰果加工厂 2022 年职业事故流行病学概况]。
Pub Date : 2024-01-01
Linda Melissa Affoue N'Guessa, André Arsène Bhellys Kouamé, Ya Madina Ouattara, Anny Adjoua Chantal Kra, Franck-Yannik Kouamé, Sangah Barthelemy Wognin

Objective: To describe the epidemiological characteristics of occupational accidents occurring in 2022 among workers at a cashew nut processing plant in Côte d'Ivoire.

Material and method: We conducted a retrospective descriptive study of occupational accidents occurring between January 1 and December 31, 2022. Data were recorded on a survey form using information from work accident registers and declaration forms.

Results: We recorded 211 work-related accidents, most of them involving women (77%) with an average age of 28 ± 8.21 years. The workers most affected were huskers (42.7%), day laborers (92.4%), not affiliated to a social security organization. Work-related accidents per se (95%) occurred between 6 a.m. and 2 p.m. (74%), after contact with a chemical substance (32.2%) or intraocular projection of a foreign body (27%). Injuries were superficial trauma and wounds (40.7%), burns (32.3%) and intraocular foreign bodies (25.1%).

Conclusion: Occupational accidents are a reality in cashew nut processing. Preventing these accidents requires not only collective preventive measures, but also the effective use of appropriate personal protective equipment.

目的:描述科特迪瓦腰果加工厂工人在 2022 年发生的职业事故的流行病学特征:描述科特迪瓦腰果加工厂工人在 2022 年发生的工伤事故的流行病学特征:我们对 2022 年 1 月 1 日至 12 月 31 日期间发生的职业事故进行了回顾性描述研究。数据通过工伤事故登记表和申报表中的信息记录在调查表中:我们记录了 211 起工伤事故,其中大部分涉及女性(77%),平均年龄为 28 ± 8.21 岁。受影响最大的工人是未加入社会保障组织的砻工(42.7%)和日工(92.4%)。工伤事故本身(95%)发生在上午 6 时至下午 2 时之间(74%),发生在接触化学物质(32.2%)或异物进入眼内(27%)之后。受伤情况为表皮外伤和伤口(40.7%)、烧伤(32.3%)和眼内异物(25.1%):结论:职业事故是腰果加工过程中的现实问题。预防这些事故不仅需要采取集体预防措施,还需要有效使用适当的个人防护设备。
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引用次数: 0
[Factors associated with Covid 19 vaccines Hesitancy in Mali, household survey, 2021]. [马里家庭调查,2021 年]。
Pub Date : 2024-01-01
Moctar Tounkara, Nouhoum Telly, Cheick Oumar Doumbia, Samba Diarra, Aissata Sacko, Daniela Fusco, Seydou Doumbia

Introduction: The objective is to evaluate factors associated with Covid 19 vaccine hesitancy in Mali.

Methods: A cross-sectional survey was conducted among the general population aged 18 and over, in rural and urban areas in Mali. Two-stage sampling was used. The number of participants to be surveyed was determined using probability proportional to size. For the identification of the households, we used the technique of the coordinates of the satellite positioning system. Logistic regression was applied to examine associations.

Results: The age group of 31 to 59 years represented 58.04% of the participants. The male sex represented with 53.26. Vaccination coverage represented 29.13% and hesitation to vaccination represented 49.30%. Participants who aged up to 60 are 49% less likely to hesitate to get vaccinated.

Conclusion: Public health interventions targeted at populations in the age group 31 to 59, women living in urban areas and who have attended school could reduce hesitation to vaccinate against Covid-19.

引言目的是评估马里人对 Covid 19 疫苗犹豫不决的相关因素:对马里农村和城市地区 18 岁及以上的普通人群进行了横断面调查。调查采用两阶段抽样。参与调查的人数按概率大小比例确定。在确定住户时,我们使用了卫星定位系统坐标技术。采用逻辑回归法研究相关性:结果:31 至 59 岁年龄组的参与者占 58.04%。男性占 53.26%。疫苗接种覆盖率为 29.13%,对疫苗接种犹豫不决者占 49.30%。60 岁以下的参与者在接种疫苗时犹豫不决的可能性要低 49%:结论:针对 31 至 59 岁年龄组、生活在城市地区和上过学的妇女的公共卫生干预措施可以减少对接种 Covid-19 疫苗的犹豫。
{"title":"[Factors associated with Covid 19 vaccines Hesitancy in Mali, household survey, 2021].","authors":"Moctar Tounkara, Nouhoum Telly, Cheick Oumar Doumbia, Samba Diarra, Aissata Sacko, Daniela Fusco, Seydou Doumbia","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The objective is to evaluate factors associated with Covid 19 vaccine hesitancy in Mali.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among the general population aged 18 and over, in rural and urban areas in Mali. Two-stage sampling was used. The number of participants to be surveyed was determined using probability proportional to size. For the identification of the households, we used the technique of the coordinates of the satellite positioning system. Logistic regression was applied to examine associations.</p><p><strong>Results: </strong>The age group of 31 to 59 years represented 58.04% of the participants. The male sex represented with 53.26. Vaccination coverage represented 29.13% and hesitation to vaccination represented 49.30%. Participants who aged up to 60 are 49% less likely to hesitate to get vaccinated.</p><p><strong>Conclusion: </strong>Public health interventions targeted at populations in the age group 31 to 59, women living in urban areas and who have attended school could reduce hesitation to vaccinate against Covid-19.</p>","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 3","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Simultaneous Quadruple Therapy In The Treatment Of Helicobacter Pylori During Peptic Ulcer Disease]. [同时使用四联疗法治疗幽门螺旋杆菌消化性溃疡病]。
Pub Date : 2024-01-01
Sanra Déborah Sanogo, Kadiatou Doumbia, Hourouma Sow, Alassane Diarra, Oumarou Youssoufou, Moussay Dicko, Makan Siré Tounkara, Abdoulaye Maiga, Ouatou Mallé, Ganda Soumaré, Hamadoun Guindo, Raphael Sidibé, Sabine Drabo, Anselme Konaté, Moussa T Diarra

Helicobacter pylori (Hp) infection plays an important role in the genesis of peptic ulcer disease. In the absence of susceptibility testing, concomitant quadruple therapy is one of the most widely used eradication methods. In the absence of a study on four-drug therapy and the difficulty of studying antibiotic susceptibility in our context, we initiated this work in order to evaluate the efficacy of an empirical treatment with concomitant four-drug therapy currently available.

Method: This was a prospective study from May 2020 to April 2021 in the Hepato Gastroenterology Department of the Gabriel Touré University Hospital, the "Les ETOILES" Clinics, "Promenade des Angevins", FARAKO". The study included peptic ulcer patients who underwent gastric biopsies for Hp, concomitant quadruple therapy, and patients were screened for endoscopic ulcer control with biopsies for Hp eradication at least four weeks after treatment.

Result: We obtained an overall frequency of Hp infection at 79% of the general population in peptic ulcer disease. This frequency was 80% in duodenal ulcer and 77.4% in gastric ulcer. The mean age was 49.05 ±17.25 years with extremes of 22 and 105 years and a sex ratio of 2.4 M/F. Epigastric pain dominated the symptomatology and with 81.6% of cases. The eradication rate was 94.7% (36/38) of cases with a healing rate of 89.5% (34/38) of cases. Histological lesions remained almost constant after treatment.

Conclusion: Concomitant quadruple therapy is effective on Hp eradication.

幽门螺杆菌(Hp)感染在消化性溃疡病的发病过程中起着重要作用。在缺乏药敏试验的情况下,同时使用四联疗法是最广泛使用的根除方法之一。由于缺乏关于四联疗法的研究,而且在我国很难研究抗生素的药敏性,因此我们启动了这项工作,以评估目前可用的四联疗法的经验性治疗效果:这是一项前瞻性研究,于 2020 年 5 月至 2021 年 4 月在加布里埃尔-杜尔大学医院消化内科、"Les ETOILES "诊所、"Promenade des Angevins "诊所和 "FARAKO "诊所进行。研究对象包括消化性溃疡患者,他们接受了胃活检以检测 Hp,同时接受了四联疗法,并在治疗后至少四周接受了内镜下溃疡控制筛查,活检以检测 Hp 是否根除:结果:我们发现,在消化性溃疡病患者中,感染 Hp 的总人数占总人数的 79%。十二指肠溃疡的感染率为 80%,胃溃疡为 77.4%。平均年龄为 49.05 ± 17.25 岁,极端年龄为 22 岁和 105 岁,男女比例为 2.4。症状以上腹疼痛为主,占病例总数的 81.6%。根除率为 94.7%(36/38),痊愈率为 89.5%(34/38)。治疗后组织学病变几乎保持不变:结论:四联疗法对根除 Hp 有效。
{"title":"[Simultaneous Quadruple Therapy In The Treatment Of Helicobacter Pylori During Peptic Ulcer Disease].","authors":"Sanra Déborah Sanogo, Kadiatou Doumbia, Hourouma Sow, Alassane Diarra, Oumarou Youssoufou, Moussay Dicko, Makan Siré Tounkara, Abdoulaye Maiga, Ouatou Mallé, Ganda Soumaré, Hamadoun Guindo, Raphael Sidibé, Sabine Drabo, Anselme Konaté, Moussa T Diarra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Helicobacter pylori (Hp) infection plays an important role in the genesis of peptic ulcer disease. In the absence of susceptibility testing, concomitant quadruple therapy is one of the most widely used eradication methods. In the absence of a study on four-drug therapy and the difficulty of studying antibiotic susceptibility in our context, we initiated this work in order to evaluate the efficacy of an empirical treatment with concomitant four-drug therapy currently available.</p><p><strong>Method: </strong>This was a prospective study from May 2020 to April 2021 in the Hepato Gastroenterology Department of the Gabriel Touré University Hospital, the \"Les ETOILES\" Clinics, \"Promenade des Angevins\", FARAKO\". The study included peptic ulcer patients who underwent gastric biopsies for Hp, concomitant quadruple therapy, and patients were screened for endoscopic ulcer control with biopsies for Hp eradication at least four weeks after treatment.</p><p><strong>Result: </strong>We obtained an overall frequency of Hp infection at 79% of the general population in peptic ulcer disease. This frequency was 80% in duodenal ulcer and 77.4% in gastric ulcer. The mean age was 49.05 ±17.25 years with extremes of 22 and 105 years and a sex ratio of 2.4 M/F. Epigastric pain dominated the symptomatology and with 81.6% of cases. The eradication rate was 94.7% (36/38) of cases with a healing rate of 89.5% (34/38) of cases. Histological lesions remained almost constant after treatment.</p><p><strong>Conclusion: </strong>Concomitant quadruple therapy is effective on Hp eradication.</p>","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 1","pages":"45-48"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Le Mali medical
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