首页 > 最新文献

Mayo Clinic Proceedings. Digital health最新文献

英文 中文
Optimizing Digital Management of Research and Collaboration With Academic Information Manager 利用学术信息管理优化研究与合作的数字化管理
Pub Date : 2025-04-16 DOI: 10.1016/j.mcpdig.2025.100222
Peyman Nejat MD , Vitali Fedosov MD, PhD , Chady Meroueh MD , Hugo Botha MB, ChB , Svetlana Herasevich MD, MS , Ing Tiong MS, MA , David Martin MD, PhD , Brian W. Pickering MD, MS , Vitaly Herasevich MD, PhD

Objective

To evaluate the efficacy, efficiency, and usability of the current iteration of the fully automatic Academic Information Manager (AIM) within the Department of Anesthesiology and Perioperative Medicine.

Participants and Methods

AIM was designed, developed, and deployed to address the growing need for digital information management in academic research. In a randomized, unblinded crossover study from April 1, 2020 to August 1, 2020, 15 participants completed 8 tasks using both AIM and conventional information retrieval methods. We assessed task completion time (efficiency), task completion status and accuracy (efficacy), subjective mental workload using the National Aeronautics and Space Administration Task Load Index (NASA-TLX), and system usability using System Usability Scale questionnaire, with and without AIM.

Results

Using AIM resulted in a significant time saving, with significantly higher task completion (99% vs 57%) and accuracy (99% vs 59%) compared with conventional methods. The NASA-TLX scores with AIM showed a statistically significant decrease in mental demand, temporal demand, effort, and frustration, along with an increase in performance, compared with those without AIM. The System Usability Scale score for AIM was above the 90th percentile.

Conclusion

Using AIM, we observed a significant increase in efficacy and efficiency, along with a decreased mental workload, as measured by NASA-TLX, and improved usability scores. Implementing AIM will help new investigators quickly and intuitively identify ongoing research at our institution. It will also enable them to broadcast their research interests to find potential collaborators.
目的评价麻醉与围手术期医学部现有全自动学术信息管理系统(AIM)的有效性、效率和可用性。saim的设计、开发和部署是为了满足学术研究中对数字信息管理日益增长的需求。在2020年4月1日至2020年8月1日的随机、非盲交叉研究中,15名参与者分别使用AIM和传统信息检索方法完成8项任务。我们评估了任务完成时间(效率)、任务完成状态和准确性(功效)、主观心理负荷(美国国家航空航天局任务负荷指数(NASA-TLX))和系统可用性(系统可用性量表)问卷,分别使用和不使用AIM。结果与常规方法相比,使用AIM可显著节省时间,任务完成率(99% vs 57%)和准确率(99% vs 59%)均显著提高。与没有AIM的人相比,有AIM的NASA-TLX分数在精神需求、时间需求、努力和挫败感方面都有统计学上的显著下降,同时表现也有所提高。AIM的系统可用性量表得分高于90个百分位数。使用AIM,我们观察到疗效和效率显著提高,同时减少了NASA-TLX测量的精神工作量,并提高了可用性分数。实施AIM将帮助新的研究人员快速直观地识别我们机构正在进行的研究。它还将使他们能够传播自己的研究兴趣,以寻找潜在的合作者。
{"title":"Optimizing Digital Management of Research and Collaboration With Academic Information Manager","authors":"Peyman Nejat MD ,&nbsp;Vitali Fedosov MD, PhD ,&nbsp;Chady Meroueh MD ,&nbsp;Hugo Botha MB, ChB ,&nbsp;Svetlana Herasevich MD, MS ,&nbsp;Ing Tiong MS, MA ,&nbsp;David Martin MD, PhD ,&nbsp;Brian W. Pickering MD, MS ,&nbsp;Vitaly Herasevich MD, PhD","doi":"10.1016/j.mcpdig.2025.100222","DOIUrl":"10.1016/j.mcpdig.2025.100222","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the efficacy, efficiency, and usability of the current iteration of the fully automatic Academic Information Manager (AIM) within the Department of Anesthesiology and Perioperative Medicine.</div></div><div><h3>Participants and Methods</h3><div>AIM was designed, developed, and deployed to address the growing need for digital information management in academic research. In a randomized, unblinded crossover study from April 1, 2020 to August 1, 2020, 15 participants completed 8 tasks using both AIM and conventional information retrieval methods. We assessed task completion time (efficiency), task completion status and accuracy (efficacy), subjective mental workload using the National Aeronautics and Space Administration Task Load Index (NASA-TLX), and system usability using System Usability Scale questionnaire, with and without AIM.</div></div><div><h3>Results</h3><div>Using AIM resulted in a significant time saving, with significantly higher task completion (99% vs 57%) and accuracy (99% vs 59%) compared with conventional methods. The NASA-TLX scores with AIM showed a statistically significant decrease in mental demand, temporal demand, effort, and frustration, along with an increase in performance, compared with those without AIM. The System Usability Scale score for AIM was above the 90th percentile.</div></div><div><h3>Conclusion</h3><div>Using AIM, we observed a significant increase in efficacy and efficiency, along with a decreased mental workload, as measured by NASA-TLX, and improved usability scores. Implementing AIM will help new investigators quickly and intuitively identify ongoing research at our institution. It will also enable them to broadcast their research interests to find potential collaborators.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100222"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
InfoKids+: A Validation Study of a Pediatric Acuity Risk Stratification Algorithm InfoKids+:一项儿科急性风险分层算法的验证研究
Pub Date : 2025-04-15 DOI: 10.1016/j.mcpdig.2025.100220
Carl A. Starvaggi MD , Sophie Affentranger MMed , Noelie Lengeler MMed , Johan N. Siebert MD , Annick Galetto-Lacour MD , Rainer Tan PhD , Manon Jaboyedoff MD , Claudia E. Kuehni MD , Mary-Anne Hartley PhD , Kristina Keitel PhD

Objective

To prospectively validate InfoKids+, a pediatric acuity electronic risk stratification algorithm (eRSA), against a nurse-based triage standard (nbTS).

Participants and Methods

We conducted a prospective validation study in a Swiss university hospital pediatric emergency department to assess the performance of a pediatric acuity eRSA, InfoKids+, on the basis of a well-established parental guidance application, InfoKids. Participants completed the eRSA once seated in a consultation booth. We compared the acuity levels from InfoKids+ (urgent, <4 hours; nonurgent, <24 hours; and no emergency, ≥24 hours) against an nbTS. The primary outcome was the level of agreement and rate of alignment between InfoKids+ and the reference standard.

Results

We included 1990 participants from June 3, 2020, through January 31, 2022. InfoKids+ showed a slight level of agreement with the nbTS (κlw=0.08; 95% CI, 0.06-0.10). InfoKids+ triaged 1762 (89%) cases as urgent (<4 hours), 106 (5%) as nonurgent (≤24 hours), and 122 (6%) as no emergency (≥24 hours), compared with 810 (41%), 843 (42%), and 337 (17%) triages by the nbTS, respectively (P<.001). InfoKids+ acuity level aligned with the reference standard in 888 (45%) cases, whereas it overreferred and underreferred in 999 (50%) and 103 (5%) cases, respectively (P<.001).

Conclusion

In summary, our study uncovered notable discrepancies between the InfoKids+ algorithmic triage and conventional nurse-based triage. Our results highlight the critical need for rigorous validation of such tools for accuracy and safety before public release to ensure these tools are beneficial and do not inadvertently cause harm or misallocation of resources.
目的针对基于护士的分诊标准(nbTS),对儿童急症电子风险分层算法(eRSA) InfoKids+进行前瞻性验证。参与者和方法我们在瑞士一所大学医院的儿科急诊科进行了一项前瞻性验证研究,在完善的家长指导应用程序InfoKids的基础上,评估儿童视力eRSA (InfoKids+)的性能。参与者坐在咨询台后完成eRSA。我们比较了InfoKids+(紧急,4小时;非紧急,24小时;无紧急情况,≥24小时)。主要结果是InfoKids+与参考标准之间的一致性水平和一致性率。从2020年6月3日到2022年1月31日,我们纳入了1990名参与者。InfoKids+与nbTS略有一致(κlw=0.08;95% ci, 0.06-0.10)。InfoKids+将1762例(89%)病例分类为紧急(4小时),106例(5%)为非紧急(≤24小时),122例(6%)为无紧急(≥24小时),而nbTS分别为810例(41%),843例(42%)和337例(17%)(P< 001)。在888例(45%)病例中,InfoKids+视力水平符合参考标准,而在999例(50%)和103例(5%)病例中,InfoKids+视力水平过高和过低(P<.001)。总之,我们的研究揭示了InfoKids+算法分诊与传统护士分诊之间的显著差异。我们的结果强调了在公开发布之前对这些工具的准确性和安全性进行严格验证的关键需求,以确保这些工具是有益的,不会无意中造成伤害或资源分配不当。
{"title":"InfoKids+: A Validation Study of a Pediatric Acuity Risk Stratification Algorithm","authors":"Carl A. Starvaggi MD ,&nbsp;Sophie Affentranger MMed ,&nbsp;Noelie Lengeler MMed ,&nbsp;Johan N. Siebert MD ,&nbsp;Annick Galetto-Lacour MD ,&nbsp;Rainer Tan PhD ,&nbsp;Manon Jaboyedoff MD ,&nbsp;Claudia E. Kuehni MD ,&nbsp;Mary-Anne Hartley PhD ,&nbsp;Kristina Keitel PhD","doi":"10.1016/j.mcpdig.2025.100220","DOIUrl":"10.1016/j.mcpdig.2025.100220","url":null,"abstract":"<div><h3>Objective</h3><div>To prospectively validate InfoKids+, a pediatric acuity electronic risk stratification algorithm (eRSA), against a nurse-based triage standard (nbTS).</div></div><div><h3>Participants and Methods</h3><div>We conducted a prospective validation study in a Swiss university hospital pediatric emergency department to assess the performance of a pediatric acuity eRSA, InfoKids+, on the basis of a well-established parental guidance application, InfoKids. Participants completed the eRSA once seated in a consultation booth. We compared the acuity levels from InfoKids+ (urgent, &lt;4 hours; nonurgent, &lt;24 hours; and no emergency, ≥24 hours) against an nbTS. The primary outcome was the level of agreement and rate of alignment between InfoKids+ and the reference standard.</div></div><div><h3>Results</h3><div>We included 1990 participants from June 3, 2020, through January 31, 2022. InfoKids+ showed a slight level of agreement with the nbTS (κ<sub>lw</sub>=0.08; 95% CI, 0.06-0.10). InfoKids+ triaged 1762 (89%) cases as urgent (&lt;4 hours), 106 (5%) as nonurgent (≤24 hours), and 122 (6%) as no emergency (≥24 hours), compared with 810 (41%), 843 (42%), and 337 (17%) triages by the nbTS, respectively (<em>P</em>&lt;.001). InfoKids+ acuity level aligned with the reference standard in 888 (45%) cases, whereas it overreferred and underreferred in 999 (50%) and 103 (5%) cases, respectively (<em>P</em>&lt;.001).</div></div><div><h3>Conclusion</h3><div>In summary, our study uncovered notable discrepancies between the InfoKids+ algorithmic triage and conventional nurse-based triage. Our results highlight the critical need for rigorous validation of such tools for accuracy and safety before public release to ensure these tools are beneficial and do not inadvertently cause harm or misallocation of resources.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100220"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender Disparities in Artificial Intelligence–Generated Images of Hospital Leadership in the United States 美国人工智能生成的医院领导图像中的性别差异
Pub Date : 2025-04-08 DOI: 10.1016/j.mcpdig.2025.100218
Mia Gisselbaek MD , Joana Berger-Estilita MD, PhD , Laurens Minsart MD , Ekin Köselerli MD , Arnout Devos PhD , Francisco Maio Matos PhD , Odmara L. Barreto Chang MD, PhD , Peter Dieckmann PhD , Melanie Suppan MD , Sarah Saxena MD, PhD

Objective

To evaluate demographic representation in artificial intelligence (AI)–generated images of hospital leadership roles and compare them with real-world data from US hospitals.

Patients and Methods

This cross-sectional study, conducted from October 1, 2024 to October 31, 2024, analyzed images generated by 3 AI text-to-image models: Midjourney 6.0, OpenAI ChatGPT DALL-E 3, and Google Gemini Imagen 3. Standardized prompts were used to create 1200 images representing 4 key leadership roles: chief executive officers, chief medical officers, chief nursing officers, and chief financial officers. Real-world demographic data from 4397 US hospitals showed that chief executive officers were 73.2% men; chief financial officers, 65.2% men; chief medical officers, 85.7% men; and chief nursing officers, 9.4% men (overall: 60.1% men). The primary outcome was gender representation, with secondary outcomes including race/ethnicity and age. Two independent reviewers assessed images, with interrater reliability evaluated using Cohen κ.

Results

Interrater agreement was high for gender (κ=0.998) and moderate for race/ethnicity (κ=0.670) and age (κ=0.605). DALL-E overrepresented men (86.5%) and White individuals (94.5%). Midjourney showed improved gender balance (69.5% men) but overrepresented White individuals (75.0%). Imagen achieved near gender parity (50.3% men) but remained predominantly White (51.5%). Statistically significant differences were observed across models and between models and real-world demographics.

Conclusion

Artificial intelligence text-to-image models reflect and amplify systemic biases, overrepresenting men and White leaders, while underrepresenting diversity. Ethical AI practices, including diverse training data sets and fairness-aware algorithms, are essential to ensure equitable representation in health care leadership.
目的评估人工智能(AI)生成的医院领导角色图像中的人口统计学代表性,并将其与来自美国医院的真实数据进行比较。患者和方法本横断面研究于2024年10月1日至2024年10月31日进行,分析了3种AI文本到图像模型生成的图像:Midjourney 6.0、OpenAI ChatGPT DALL-E 3和谷歌Gemini Imagen 3。使用标准化提示创建了1200个代表4个关键领导角色的图像:首席执行官、首席医疗官、首席护理官和首席财务官。来自美国4397家医院的真实人口统计数据显示,首席执行官中有73.2%是男性;首席财务官中,男性占65.2%;首席医务官,85.7%为男性;首席护理官中,9.4%是男性(总体:60.1%是男性)。主要结果是性别代表性,次要结果包括种族/民族和年龄。两名独立审稿人对图像进行评估,使用Cohen κ评估图像间信度。结果性别间的一致性较高(κ=0.998),种族/民族间的一致性中等(κ=0.670),年龄间的一致性中等(κ=0.605)。DALL-E在男性(86.5%)和白人(94.5%)中比例过高。中期显示性别平衡有所改善(69.5%为男性),但白人个体比例过高(75.0%)。Imagen几乎实现了性别平等(50.3%的男性),但仍以白人为主(51.5%)。在模型之间以及模型与现实世界人口统计数据之间观察到统计学上的显著差异。人工智能文本到图像模型反映并放大了系统性偏见,过度代表男性和白人领导者,而低估了多样性。道德人工智能实践,包括各种训练数据集和公平意识算法,对于确保卫生保健领导层的公平代表性至关重要。
{"title":"Gender Disparities in Artificial Intelligence–Generated Images of Hospital Leadership in the United States","authors":"Mia Gisselbaek MD ,&nbsp;Joana Berger-Estilita MD, PhD ,&nbsp;Laurens Minsart MD ,&nbsp;Ekin Köselerli MD ,&nbsp;Arnout Devos PhD ,&nbsp;Francisco Maio Matos PhD ,&nbsp;Odmara L. Barreto Chang MD, PhD ,&nbsp;Peter Dieckmann PhD ,&nbsp;Melanie Suppan MD ,&nbsp;Sarah Saxena MD, PhD","doi":"10.1016/j.mcpdig.2025.100218","DOIUrl":"10.1016/j.mcpdig.2025.100218","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate demographic representation in artificial intelligence (AI)–generated images of hospital leadership roles and compare them with real-world data from US hospitals.</div></div><div><h3>Patients and Methods</h3><div>This cross-sectional study, conducted from October 1, 2024 to October 31, 2024, analyzed images generated by 3 AI text-to-image models: Midjourney 6.0, OpenAI ChatGPT DALL-E 3, and Google Gemini Imagen 3. Standardized prompts were used to create 1200 images representing 4 key leadership roles: chief executive officers, chief medical officers, chief nursing officers, and chief financial officers. Real-world demographic data from 4397 US hospitals showed that chief executive officers were 73.2% men; chief financial officers, 65.2% men; chief medical officers, 85.7% men; and chief nursing officers, 9.4% men (overall: 60.1% men). The primary outcome was gender representation, with secondary outcomes including race/ethnicity and age. Two independent reviewers assessed images, with interrater reliability evaluated using Cohen κ.</div></div><div><h3>Results</h3><div>Interrater agreement was high for gender (κ=0.998) and moderate for race/ethnicity (κ=0.670) and age (κ=0.605). DALL-E overrepresented men (86.5%) and White individuals (94.5%). Midjourney showed improved gender balance (69.5% men) but overrepresented White individuals (75.0%). Imagen achieved near gender parity (50.3% men) but remained predominantly White (51.5%). Statistically significant differences were observed across models and between models and real-world demographics.</div></div><div><h3>Conclusion</h3><div>Artificial intelligence text-to-image models reflect and amplify systemic biases, overrepresenting men and White leaders, while underrepresenting diversity. Ethical AI practices, including diverse training data sets and fairness-aware algorithms, are essential to ensure equitable representation in health care leadership.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100218"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum to “Impact of Ambient Artificial Intelligence Documentation on Cognitive Load” “环境人工智能文档对认知负荷的影响”的勘误
Pub Date : 2025-04-04 DOI: 10.1016/j.mcpdig.2025.100219
{"title":"Erratum to “Impact of Ambient Artificial Intelligence Documentation on Cognitive Load”","authors":"","doi":"10.1016/j.mcpdig.2025.100219","DOIUrl":"10.1016/j.mcpdig.2025.100219","url":null,"abstract":"","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100219"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying the Unknowns of Plaque Morphology: The Role of Topological Uncertainty in Coronary Artery Disease 量化未知斑块形态:拓扑不确定性在冠状动脉疾病中的作用
Pub Date : 2025-03-28 DOI: 10.1016/j.mcpdig.2025.100217
Yashbir Singh ME, PhD , Quincy A. Hathaway MD, PhD , Karthik Dinakar PhD , Leslee J. Shaw PhD , Bradley Erickson MD, PhD , Francisco Lopez-Jimenez MD, MBA, MSc , Deepak L. Bhatt MD, MPH, MBA
This article aimed to explore topological uncertainty in medical imaging, particularly in assessing coronary artery calcification using artificial intelligence (AI). Topological uncertainty refers to ambiguities in spatial and structural characteristics of medical features, which can impact the interpretation of coronary plaques. The article discusses the challenges of integrating AI with topological considerations and the need for specialized methodologies beyond traditional performance metrics. It highlights advancements in quantifying topological uncertainty, including the use of persistent homology and topological data analysis techniques. The importance of standardization in methodologies and ethical considerations in AI deployment are emphasized. It also outlines various types of uncertainty in topological frameworks for coronary plaques, categorizing them as quantifiable and controllable or quantifiable and not controllable. Future directions include developing AI algorithms that incorporate topological insights, establishing standardized protocols, and exploring ethical implications to revolutionize cardiovascular care through personalized treatment plans guided by sophisticated topological analysis. Recognizing and quantifying topological uncertainty in medical imaging as AI emerges is critical. Exploring topological uncertainty in coronary artery disease will revolutionize cardiovascular care, promising enhanced precision and personalization in diagnostics and treatment for millions affected by cardiovascular diseases.
本文旨在探讨医学成像中的拓扑不确定性,特别是使用人工智能(AI)评估冠状动脉钙化。拓扑不确定性是指医学特征的空间和结构特征的模糊性,这可能影响冠状动脉斑块的解释。本文讨论了将人工智能与拓扑因素集成的挑战,以及对传统性能指标之外的专门方法的需求。它强调了量化拓扑不确定性的进展,包括使用持久同调和拓扑数据分析技术。强调了人工智能部署中方法标准化和伦理考虑的重要性。它还概述了冠状动脉斑块拓扑框架中的各种类型的不确定性,将其分类为可量化和可控或可量化和不可控制。未来的方向包括开发包含拓扑洞察的人工智能算法,建立标准化协议,以及探索伦理影响,通过复杂拓扑分析指导的个性化治疗计划彻底改变心血管护理。随着人工智能的出现,识别和量化医学成像中的拓扑不确定性至关重要。探索冠状动脉疾病的拓扑不确定性将彻底改变心血管护理,有望提高数百万受心血管疾病影响的诊断和治疗的准确性和个性化。
{"title":"Quantifying the Unknowns of Plaque Morphology: The Role of Topological Uncertainty in Coronary Artery Disease","authors":"Yashbir Singh ME, PhD ,&nbsp;Quincy A. Hathaway MD, PhD ,&nbsp;Karthik Dinakar PhD ,&nbsp;Leslee J. Shaw PhD ,&nbsp;Bradley Erickson MD, PhD ,&nbsp;Francisco Lopez-Jimenez MD, MBA, MSc ,&nbsp;Deepak L. Bhatt MD, MPH, MBA","doi":"10.1016/j.mcpdig.2025.100217","DOIUrl":"10.1016/j.mcpdig.2025.100217","url":null,"abstract":"<div><div>This article aimed to explore topological uncertainty in medical imaging, particularly in assessing coronary artery calcification using artificial intelligence (AI). Topological uncertainty refers to ambiguities in spatial and structural characteristics of medical features, which can impact the interpretation of coronary plaques. The article discusses the challenges of integrating AI with topological considerations and the need for specialized methodologies beyond traditional performance metrics. It highlights advancements in quantifying topological uncertainty, including the use of persistent homology and topological data analysis techniques. The importance of standardization in methodologies and ethical considerations in AI deployment are emphasized. It also outlines various types of uncertainty in topological frameworks for coronary plaques, categorizing them as quantifiable and controllable or quantifiable and not controllable. Future directions include developing AI algorithms that incorporate topological insights, establishing standardized protocols, and exploring ethical implications to revolutionize cardiovascular care through personalized treatment plans guided by sophisticated topological analysis. Recognizing and quantifying topological uncertainty in medical imaging as AI emerges is critical. Exploring topological uncertainty in coronary artery disease will revolutionize cardiovascular care, promising enhanced precision and personalization in diagnostics and treatment for millions affected by cardiovascular diseases.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100217"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Digital Interventions in Occupational Health Care: A Systematic Review 数字干预对职业卫生保健的影响:系统综述
Pub Date : 2025-03-18 DOI: 10.1016/j.mcpdig.2025.100216
Mirjam M. Jern-Matintupa MD, MPH , Anita M. Riipinen MD, PhD , Merja K. Laine MD, PhD

Objective

To assess the existing body of evidence and impact of digital interventions on occupational health care.

Methods

The search strategy and review process were conducted in accordance with the PRISMA guidelines. The search was carried out during a period from January 1, 2013 to June 5, 2023, using the SCOPUS and Ovid Medline databases. After the identification of the relevant records, screening was conducted in 3 stages, following specific predetermined inclusion and exclusion criteria. A data-extraction model was created on the basis of the aim of the review. The quality of the selected studies was evaluated using the Effective Public Health Practice framework. Owing to the heterogeneity of the outcome measures, we used narrative synthesis to summarize the findings.

Results

We identified 382 records in SCOPUS and 441 in Ovid Medline. We selected 54 studies to be included in the evidence synthesis. The health targets of the interventions varied widely, but we identified 2 main focus areas: sedentary behavior (n=17, 32%) and mental health (n=14, 26%). Even when the studies had the same health target, the outcomes and chosen measures varied widely. Given the considerable effect of the primary outcome, mental health appears to be a good target for digital interventions. Online training and computer software could be especially effective.

Conclusion

The potential positive impact of digital interventions on mental health, especially online training, should be leveraged by health care professionals and providers. In order to provide more specific recommendations for health care professionals, occupational health care researchers should strive for consensus on outcome measures.
目的评估现有证据和数字化干预对职业卫生保健的影响。方法按照PRISMA指南进行检索策略和评审过程。检索时间为2013年1月1日至2023年6月5日,检索对象为SCOPUS和Ovid Medline数据库。在确定相关记录后,按照特定的预定纳入和排除标准,分3个阶段进行筛查。根据综述的目的,建立了数据提取模型。所选研究的质量采用有效公共卫生实践框架进行评估。由于结果测量的异质性,我们使用叙事综合来总结研究结果。结果SCOPUS检索到382条,Ovid Medline检索到441条。我们选择了54项研究纳入证据综合。干预措施的健康目标差异很大,但我们确定了两个主要关注领域:久坐行为(n= 17,32%)和心理健康(n= 14,26%)。即使这些研究有相同的健康目标,结果和选择的测量方法也有很大的不同。鉴于主要结果的巨大影响,心理健康似乎是数字干预的一个很好的目标。在线培训和电脑软件可能特别有效。结论数字干预对心理健康的潜在积极影响,特别是在线培训,应被卫生保健专业人员和提供者利用。为了向卫生保健专业人员提供更具体的建议,职业卫生保健研究人员应该努力在结果测量上达成共识。
{"title":"Impact of Digital Interventions in Occupational Health Care: A Systematic Review","authors":"Mirjam M. Jern-Matintupa MD, MPH ,&nbsp;Anita M. Riipinen MD, PhD ,&nbsp;Merja K. Laine MD, PhD","doi":"10.1016/j.mcpdig.2025.100216","DOIUrl":"10.1016/j.mcpdig.2025.100216","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the existing body of evidence and impact of digital interventions on occupational health care.</div></div><div><h3>Methods</h3><div>The search strategy and review process were conducted in accordance with the PRISMA guidelines. The search was carried out during a period from January 1, 2013 to June 5, 2023, using the SCOPUS and Ovid Medline databases. After the identification of the relevant records, screening was conducted in 3 stages, following specific predetermined inclusion and exclusion criteria. A data-extraction model was created on the basis of the aim of the review. The quality of the selected studies was evaluated using the Effective Public Health Practice framework. Owing to the heterogeneity of the outcome measures, we used narrative synthesis to summarize the findings.</div></div><div><h3>Results</h3><div>We identified 382 records in SCOPUS and 441 in Ovid Medline. We selected 54 studies to be included in the evidence synthesis. The health targets of the interventions varied widely, but we identified 2 main focus areas: sedentary behavior (n=17, 32%) and mental health (n=14, 26%). Even when the studies had the same health target, the outcomes and chosen measures varied widely. Given the considerable effect of the primary outcome, mental health appears to be a good target for digital interventions. Online training and computer software could be especially effective.</div></div><div><h3>Conclusion</h3><div>The potential positive impact of digital interventions on mental health, especially online training, should be leveraged by health care professionals and providers. In order to provide more specific recommendations for health care professionals, occupational health care researchers should strive for consensus on outcome measures.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum to Leveraging the Metaverse for Enhanced Longevity as a Component of Health 4.0 [Mayo Clinic Proceedings: Digital Health. 2024;2:139-151] 作为健康 4.0 的一个组成部分,利用 "元宇宙 "提高寿命》的勘误 [Mayo Clinic Proceedings: Digital Health.]
Pub Date : 2025-03-12 DOI: 10.1016/j.mcpdig.2025.100215
{"title":"Erratum to Leveraging the Metaverse for Enhanced Longevity as a Component of Health 4.0 [Mayo Clinic Proceedings: Digital Health. 2024;2:139-151]","authors":"","doi":"10.1016/j.mcpdig.2025.100215","DOIUrl":"10.1016/j.mcpdig.2025.100215","url":null,"abstract":"","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100215"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selecting Wearable Devices to Measure Cardiovascular Functions in Community-Dwelling Adults: Application of a Practical Guide for Device Selection 选择可穿戴设备来测量社区居住成年人的心血管功能:设备选择实用指南的应用
Pub Date : 2025-03-12 DOI: 10.1016/j.mcpdig.2025.100202
Jessica K. Lu MEng , Weilan Wang PhD , Jorming Goh PhD , Andrea B. Maier MD, PhD
Continuous monitoring of cardiovascular functions can provide crucial insights into the health status and lifestyle behaviors of an individual. Wearable devices offer a convenient and cost-effective solution for collecting cardiovascular measurements outside clinical settings. However, the abundance of available devices poses challenges for researchers, health care professionals, and device users in selecting the most suitable one. This article illustrates the application of a practical guide for selecting wearable devices for the continuous monitoring of cardiovascular functions in community-dwelling adults who are generally healthy or have minimal, well-managed chronic conditions. An initial systematic review of the literature revealed 216 devices, each of which were assessed on the basis of 5 core criteria from the guide: (1) continuous monitoring capability, (2) device availability and suitability, (3) technical performance (accuracy and precision), (4) feasibility of use, and (5) cost evaluation. From the 216 devices, there were 136 devices capable of continuous monitoring. After the exclusion of unavailable and unsuitable devices, 53 devices underwent validation assessment of accuracy and precision. Although COSMIN criteria were applied to evaluate technical performance, a lack of validation for certain devices limits a comprehensive evaluation. After selection of valid devices, the feasibility and cost of 20 devices were examined. Wearable devices, such as the Apple Watch Series 9, Fitbit Charge 6, Garmin vívosmart 5, and Oura Ring Gen3, emerged as suitable devices to measure cardiovascular function in community-dwelling adults. The systematic process for device selection could also be applied to select wearable devices for the measurement of other physiologic variables and lifestyle behaviors.
持续监测心血管功能可以对个人的健康状况和生活方式行为提供重要的见解。可穿戴设备为在临床环境之外收集心血管测量数据提供了一种方便且经济高效的解决方案。然而,大量的可用设备给研究人员、卫生保健专业人员和设备用户在选择最合适的设备方面带来了挑战。本文阐述了一种实用指南的应用,用于选择可穿戴设备,用于持续监测社区居住成年人的心血管功能,这些成年人通常健康或有最小的、管理良好的慢性病。对文献的初步系统回顾显示了216个设备,每个设备都是根据指南中的5个核心标准进行评估的:(1)持续监测能力,(2)设备可用性和适用性,(3)技术性能(准确性和精密度),(4)使用可行性,(5)成本评估。在216个装置中,有136个装置能够持续监测。在排除不可用和不合适的器械后,53个器械进行了准确性和精密度的验证评估。虽然采用了COSMIN标准来评价技术性能,但缺乏对某些设备的验证限制了全面评价。在选择了有效装置后,对20种装置的可行性和成本进行了考察。可穿戴设备,如Apple Watch Series 9、Fitbit Charge 6、Garmin vívosmart 5和Oura Ring Gen3,成为测量社区居民心血管功能的合适设备。设备选择的系统过程也可以应用于选择可穿戴设备来测量其他生理变量和生活方式行为。
{"title":"Selecting Wearable Devices to Measure Cardiovascular Functions in Community-Dwelling Adults: Application of a Practical Guide for Device Selection","authors":"Jessica K. Lu MEng ,&nbsp;Weilan Wang PhD ,&nbsp;Jorming Goh PhD ,&nbsp;Andrea B. Maier MD, PhD","doi":"10.1016/j.mcpdig.2025.100202","DOIUrl":"10.1016/j.mcpdig.2025.100202","url":null,"abstract":"<div><div>Continuous monitoring of cardiovascular functions can provide crucial insights into the health status and lifestyle behaviors of an individual. Wearable devices offer a convenient and cost-effective solution for collecting cardiovascular measurements outside clinical settings. However, the abundance of available devices poses challenges for researchers, health care professionals, and device users in selecting the most suitable one. This article illustrates the application of a practical guide for selecting wearable devices for the continuous monitoring of cardiovascular functions in community-dwelling adults who are generally healthy or have minimal, well-managed chronic conditions. An initial systematic review of the literature revealed 216 devices, each of which were assessed on the basis of 5 core criteria from the guide: (1) continuous monitoring capability, (2) device availability and suitability, (3) technical performance (accuracy and precision), (4) feasibility of use, and (5) cost evaluation. From the 216 devices, there were 136 devices capable of continuous monitoring. After the exclusion of unavailable and unsuitable devices, 53 devices underwent validation assessment of accuracy and precision. Although COSMIN criteria were applied to evaluate technical performance, a lack of validation for certain devices limits a comprehensive evaluation. After selection of valid devices, the feasibility and cost of 20 devices were examined. Wearable devices, such as the Apple Watch Series 9, Fitbit Charge 6, Garmin vívosmart 5, and Oura Ring Gen3, emerged as suitable devices to measure cardiovascular function in community-dwelling adults. The systematic process for device selection could also be applied to select wearable devices for the measurement of other physiologic variables and lifestyle behaviors.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The PERFORM Study: Artificial Intelligence Versus Human Residents in Cross-Sectional Obstetrics-Gynecology Scenarios Across Languages and Time Constraints PERFORM研究:人工智能与人类住院医生在跨语言和时间限制的横截面妇产科场景中的对比
Pub Date : 2025-03-08 DOI: 10.1016/j.mcpdig.2025.100206
Canio Martinelli MD , Antonio Giordano MD , Vincenzo Carnevale PhD , Sharon Raffaella Burk PhD , Lavinia Porto MD , Giuseppe Vizzielli MD , Alfredo Ercoli MD

Objective

To systematically evaluate the performance of artificial intelligence (AI) large language models (LLMs) compared with obstetrics-gynecology residents in clinical decision-making, examining diagnostic accuracy and error patterns across linguistic domains, time constraints, and experience levels.

Patients and Methods

In this cross-sectional study, we evaluated 8 AI LLMs and 24 obstetrics-gynecology residents (Years 1-5) using 60 standardized clinical scenarios. Most AI LLMs and all residents were assessed in May 2024, whereas chat GPT-01-preview, chat-GPT4o, and Claude Sonnet 3.5 were evaluated in November 2024. The assessment framework incorporated English and Italian scenarios under both timed and untimed conditions, along with systematic error pattern analysis. The primary outcome was diagnostic accuracy; secondary end points included AI system stratification, resident progression, language impact, time pressure effects, and integration potential.

Results

The AI LLMs reported superior overall accuracy (73.75%; 95% confidence interval [CI], 69.64%-77.49%) compared with residents (65.35%; 95% CI, 62.85%-67.76%; P<.001). High-performing AI systems (ChatGPT-01-preview, GPT4o, and Claude Sonnet 3.5) achieved consistently high cross-linguistic accuracy (88.33%) with minimal language impact (6.67%±0.00%). Resident performance declined significantly under time constraints (from 73.2% to 56.5% adjusted accuracy; Cohen’s d=1.009; P<.001), whereas AI systems reported lesser deterioration. Error pattern analysis indicated a moderate correlation between AI and human reasoning (r=0.666; P<.001). Residents exhibited systematic progression from year 1 (44.7%) to year 5 (87.1%). Integration analysis found variable benefits across training levels, with maximum enhancement in early-career residents (+29.7%; P<.001).

Conclusion

High-performing AI LLMs reported strong diagnostic accuracy and resilience under linguistic and temporal pressures. These findings suggest that AI-enhanced decision-making may offer particular benefits in obstetrics and gynecology training programs, especially for junior residents, by improving diagnostic consistency and potentially reducing cognitive load in time-sensitive clinical settings.
目的系统评估人工智能(AI)大语言模型(llm)与妇产科住院医师在临床决策中的表现,检查跨语言领域、时间限制和经验水平的诊断准确性和错误模式。患者和方法在这项横断面研究中,我们使用60个标准化的临床场景评估了8名AI法学硕士和24名妇产科住院医师(1-5年)。大多数AI llm和所有居民在2024年5月进行评估,而chat GPT-01-preview, chat- gpt40和Claude Sonnet 3.5在2024年11月进行评估。评估框架结合了定时和非定时条件下的英语和意大利语场景,以及系统的错误模式分析。主要结局是诊断准确性;次要终点包括人工智能系统分层、居民进展、语言影响、时间压力效应和整合潜力。结果人工智能LLMs总体准确率为73.75%;95%可信区间[CI], 69.64%-77.49%),而居民(65.35%;95% ci, 62.85%-67.76%;术;措施)。高性能的人工智能系统(ChatGPT-01-preview、gpt40和Claude Sonnet 3.5)在最小的语言影响(6.67%±0.00%)下实现了持续的高跨语言准确率(88.33%)。在时间限制下,住院医生的表现显著下降(调整后准确率从73.2%降至56.5%;科恩的d = 1.009;P<.001),而人工智能系统报告的恶化程度较小。误差模式分析表明,人工智能与人类推理之间存在中度相关性(r=0.666;术;措施)。从第1年(44.7%)到第5年(87.1%),居民表现出系统的进展。综合分析发现,不同培训水平的收益各不相同,早期职业居民的收益最大(+29.7%;术;措施)。结论高性能AI llm在语言和时间压力下具有较强的诊断准确性和弹性。这些发现表明,人工智能增强的决策可以通过提高诊断一致性和潜在地减少时间敏感的临床环境中的认知负荷,为妇产科培训项目提供特别的好处,特别是对初级住院医生。
{"title":"The PERFORM Study: Artificial Intelligence Versus Human Residents in Cross-Sectional Obstetrics-Gynecology Scenarios Across Languages and Time Constraints","authors":"Canio Martinelli MD ,&nbsp;Antonio Giordano MD ,&nbsp;Vincenzo Carnevale PhD ,&nbsp;Sharon Raffaella Burk PhD ,&nbsp;Lavinia Porto MD ,&nbsp;Giuseppe Vizzielli MD ,&nbsp;Alfredo Ercoli MD","doi":"10.1016/j.mcpdig.2025.100206","DOIUrl":"10.1016/j.mcpdig.2025.100206","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically evaluate the performance of artificial intelligence (AI) large language models (LLMs) compared with obstetrics-gynecology residents in clinical decision-making, examining diagnostic accuracy and error patterns across linguistic domains, time constraints, and experience levels.</div></div><div><h3>Patients and Methods</h3><div>In this cross-sectional study, we evaluated 8 AI LLMs and 24 obstetrics-gynecology residents (Years 1-5) using 60 standardized clinical scenarios. Most AI LLMs and all residents were assessed in May 2024, whereas chat GPT-01-preview, chat-GPT4o, and Claude Sonnet 3.5 were evaluated in November 2024. The assessment framework incorporated English and Italian scenarios under both timed and untimed conditions, along with systematic error pattern analysis. The primary outcome was diagnostic accuracy; secondary end points included AI system stratification, resident progression, language impact, time pressure effects, and integration potential.</div></div><div><h3>Results</h3><div>The AI LLMs reported superior overall accuracy (73.75%; 95% confidence interval [CI], 69.64%-77.49%) compared with residents (65.35%; 95% CI, 62.85%-67.76%; <em>P</em>&lt;.001). High-performing AI systems (ChatGPT-01-preview, GPT4o, and Claude Sonnet 3.5) achieved consistently high cross-linguistic accuracy (88.33%) with minimal language impact (6.67%±0.00%). Resident performance declined significantly under time constraints (from 73.2% to 56.5% adjusted accuracy; Cohen’s d=1.009; <em>P</em>&lt;.001), whereas AI systems reported lesser deterioration. Error pattern analysis indicated a moderate correlation between AI and human reasoning (r=0.666; <em>P</em>&lt;.001). Residents exhibited systematic progression from year 1 (44.7%) to year 5 (87.1%). Integration analysis found variable benefits across training levels, with maximum enhancement in early-career residents (+29.7%; <em>P</em>&lt;.001).</div></div><div><h3>Conclusion</h3><div>High-performing AI LLMs reported strong diagnostic accuracy and resilience under linguistic and temporal pressures. These findings suggest that AI-enhanced decision-making may offer particular benefits in obstetrics and gynecology training programs, especially for junior residents, by improving diagnostic consistency and potentially reducing cognitive load in time-sensitive clinical settings.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Experience With an Optical Character Recognition Search Application for Review of Outside Medical Records” “使用光学字符识别检索程序查阅外部医疗记录的经验”的勘误表
Pub Date : 2025-03-08 DOI: 10.1016/j.mcpdig.2025.100208
{"title":"Corrigendum to “Experience With an Optical Character Recognition Search Application for Review of Outside Medical Records”","authors":"","doi":"10.1016/j.mcpdig.2025.100208","DOIUrl":"10.1016/j.mcpdig.2025.100208","url":null,"abstract":"","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"3 2","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Mayo Clinic Proceedings. Digital health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1