The abundance of circulating miRNAs-small non-coding RNAs involved in posttranscriptional regulation of gene expression- in body fluids of cancer patients holds great promise to identify stable and specific biomarkers
{"title":"Disease and Circulating miRs: Updated in the Medical World","authors":"Elham Ghazizadeh","doi":"10.52768/2993-1142/1073","DOIUrl":"https://doi.org/10.52768/2993-1142/1073","url":null,"abstract":"The abundance of circulating miRNAs-small non-coding RNAs involved in posttranscriptional regulation of gene expression- in body fluids of cancer patients holds great promise to identify stable and specific biomarkers","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139339909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Etoposide is a semisynthetic podophyllotoxin derivative that is active against several solid and hematologic malignancies. The adverse effect of this chemotherapeutic agent includes nausea, vomiting, abdominal pain, hair loss, and dizziness
{"title":"Case Report: Etoposide Induced Skin Rash in Small Cell Lung Carcinoma","authors":"Kennedy Aikins","doi":"10.52768/2993-1142/1072","DOIUrl":"https://doi.org/10.52768/2993-1142/1072","url":null,"abstract":"Etoposide is a semisynthetic podophyllotoxin derivative that is active against several solid and hematologic malignancies. The adverse effect of this chemotherapeutic agent includes nausea, vomiting, abdominal pain, hair loss, and dizziness","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seeing difficulties like blindness and partial blindness are affected by a number of intrinsic and extrinsic factors. The objective of this study is to evaluate whether seeing difficulties are associated with extrinsic (external) factors like environmental, educational, and socioeconomic status of people.
{"title":"Risk Factors for Blindness and Partial Blindness in the Amhara Region of Ethiopia: Spatial and Regression Analyses","authors":"Hailu Shifarew","doi":"10.52768/2993-1142/1071","DOIUrl":"https://doi.org/10.52768/2993-1142/1071","url":null,"abstract":"Seeing difficulties like blindness and partial blindness are affected by a number of intrinsic and extrinsic factors. The objective of this study is to evaluate whether seeing difficulties are associated with extrinsic (external) factors like environmental, educational, and socioeconomic status of people.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Papain-like protease (PLpro) is one of the most promising targets for anti-SARS-CoV drugs because it is an essential multifunctional cysteine protease for corona viral replication.
{"title":"Virtual Screening and Binding Mode Analysis of Selected FDA Approved Drugs Against PLpro Target: An Effort to Identify Therapeutics to Combat COVID-19","authors":"M. Ashouri","doi":"10.52768/2993-1142/1070","DOIUrl":"https://doi.org/10.52768/2993-1142/1070","url":null,"abstract":"Papain-like protease (PLpro) is one of the most promising targets for anti-SARS-CoV drugs because it is an essential multifunctional cysteine protease for corona viral replication.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain is a leading cause of medical complaints worldwide, underscoring the essential role of knowledge and use of opioids. Opioids are drugs that directly impact pain processing, immune functions, stress regulation, and more. They originate from opium, which is extracted from Papaver somniferum, a plant native to the Mediterranean region.
{"title":"Insights into the Endogenous Opioid System: An Overview","authors":"Manuela B Pucca","doi":"10.52768/2993-1142/1069","DOIUrl":"https://doi.org/10.52768/2993-1142/1069","url":null,"abstract":"Pain is a leading cause of medical complaints worldwide, underscoring the essential role of knowledge and use of opioids. Opioids are drugs that directly impact pain processing, immune functions, stress regulation, and more. They originate from opium, which is extracted from Papaver somniferum, a plant native to the Mediterranean region.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The most common causes of microcytic anemias are Iron Deficiency Anemia (IDA) and Beta Thalassemia minor (BTm).
背景:小细胞贫血最常见的原因是缺铁性贫血(IDA)和β地中海贫血(BTm)。
{"title":"The Efficiencies of Erythrocyte Indices in Differential Diagnosis of Beta Thalassemia Minor and Iron Deficiency Anemia","authors":"Zeynep Yildiz","doi":"10.52768/2993-1142/1061","DOIUrl":"https://doi.org/10.52768/2993-1142/1061","url":null,"abstract":"Background: The most common causes of microcytic anemias are Iron Deficiency Anemia (IDA) and Beta Thalassemia minor (BTm).","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136035541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An intermittent extrathoracic airway obstruction due to adduction of vocal cords, formerly referred to as Vocal Cord Dysfunction (VCD) and now as ILO or VCD/ILO, can lead to sudden dyspnoea of varying intensity mimicking asthma attacks.
{"title":"Inducible Laryngeal Obstruction (ILO) Coexisting with COPD can Fatally Influence the Course of COPD Exacerbation","authors":"Dariusz Ziora","doi":"10.52768/2993-1142/1067","DOIUrl":"https://doi.org/10.52768/2993-1142/1067","url":null,"abstract":"An intermittent extrathoracic airway obstruction due to adduction of vocal cords, formerly referred to as Vocal Cord Dysfunction (VCD) and now as ILO or VCD/ILO, can lead to sudden dyspnoea of varying intensity mimicking asthma attacks.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
COVID-19 may lead to a perseverance of symptoms after recovery from the disease, a condition known as long COVID, characterized by continual cognitive, somatic and behavioral symptoms.
{"title":"Long COVID-19","authors":"Leonor Chacin Bonilla","doi":"10.52768/2993-1142/1068","DOIUrl":"https://doi.org/10.52768/2993-1142/1068","url":null,"abstract":"COVID-19 may lead to a perseverance of symptoms after recovery from the disease, a condition known as long COVID, characterized by continual cognitive, somatic and behavioral symptoms.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Internet hospitals are the deep integration of Internet, information technology and medical services. Driven by new technologies such as mobile Internet, cloud computing, big data, and the Internet of Things
{"title":"Development Status of Internet Hospitals in China","authors":"Licheng Liang","doi":"10.52768/2993-1142/1063","DOIUrl":"https://doi.org/10.52768/2993-1142/1063","url":null,"abstract":"Internet hospitals are the deep integration of Internet, information technology and medical services. Driven by new technologies such as mobile Internet, cloud computing, big data, and the Internet of Things","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The X/A-like cell is an enteroendocrine cell that was initially poorly understood but has gained significant attention due to its peptide products, including ghrelin, desacyl-ghrelin, obestatin and nesfatin-1.
{"title":"Gastric X/A-Like Cell-Derived Peptides Participate Global Lipid Metabolism Regulation","authors":"Ruili Yu","doi":"10.52768/2993-1142/1066","DOIUrl":"https://doi.org/10.52768/2993-1142/1066","url":null,"abstract":"The X/A-like cell is an enteroendocrine cell that was initially poorly understood but has gained significant attention due to its peptide products, including ghrelin, desacyl-ghrelin, obestatin and nesfatin-1.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139348463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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