{"title":"Medscape General Medicine: April 9, 1999-December 31, 2007. This epilogue is not an epitaph.","authors":"George D Lundberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"64"},"PeriodicalIF":0.0,"publicationDate":"2007-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Making payment reform in the US healthcare system possible.","authors":"Karen Davis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2007-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This is a case study of a 68-year-old woman with previously unremitting depression. The patient came to our care in 1994 following a series of treatment interventions that did not alter the course of chronic depression. We report our treatment approach and results seen with this patient, including her tepid response to traditional antidepressants and the positive results seen in the past year using vagus nerve stimulation (VNS) therapy. The patient experienced broad gains in measures of depression severity and well-being under her current treatment regimen. She has had no serious adverse events associated with the regimen, which includes VNS therapy and decreased doses of common antidepressant medications.
{"title":"Improved mood and remission of symptoms in long-term major depression using vagus nerve stimulation.","authors":"Amita R Patel, Shannon M Wozniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This is a case study of a 68-year-old woman with previously unremitting depression. The patient came to our care in 1994 following a series of treatment interventions that did not alter the course of chronic depression. We report our treatment approach and results seen with this patient, including her tepid response to traditional antidepressants and the positive results seen in the past year using vagus nerve stimulation (VNS) therapy. The patient experienced broad gains in measures of depression severity and well-being under her current treatment regimen. She has had no serious adverse events associated with the regimen, which includes VNS therapy and decreased doses of common antidepressant medications.</p>","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"62"},"PeriodicalIF":0.0,"publicationDate":"2007-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A conversation about sudden unexpected death (SUDA) in \"healthy\" adults, adults with known heart disease, athletes, adolescents, and infants (SIDS). Interview by George D. Lundberg.","authors":"Eric N Prystowsky","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"61"},"PeriodicalIF":0.0,"publicationDate":"2007-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autism spectrum disorders are heterogeneous in nature with idiopathic and genetic origins. We present a 7-year-old boy with a long history of multiple behavioral concerns, poor school performance, repetitive/compulsive tendencies, poor social skills, and language delays. A multidisciplinary evaluation concluded that the patient met full criteria for autism. A genetic evaluation demonstrated Klinefelter syndrome 47, XXY karyotype with concurrent duplication of 3p21.31 by microarray analysis. Maternal genetic analysis demonstrated the same 3p21.31 duplication. The potential implication with regard to autism spectrum disorders has not been previously discussed in the literature.
{"title":"Autism spectrum disorder, Klinefelter syndrome, and chromosome 3p21.31 duplication: a case report.","authors":"Scott W Stuart, Casey H King, G Shashidar Pai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autism spectrum disorders are heterogeneous in nature with idiopathic and genetic origins. We present a 7-year-old boy with a long history of multiple behavioral concerns, poor school performance, repetitive/compulsive tendencies, poor social skills, and language delays. A multidisciplinary evaluation concluded that the patient met full criteria for autism. A genetic evaluation demonstrated Klinefelter syndrome 47, XXY karyotype with concurrent duplication of 3p21.31 by microarray analysis. Maternal genetic analysis demonstrated the same 3p21.31 duplication. The potential implication with regard to autism spectrum disorders has not been previously discussed in the literature.</p>","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"60"},"PeriodicalIF":0.0,"publicationDate":"2007-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"We physicians preach what we practice, and that matters.","authors":"Erica Frank","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2007-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Going lean in the emergency department: a strategy for addressing emergency department overcrowding.","authors":"Rick G Kulkarni","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2007-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Part 2: A reader responds to \"Ethics and evidence-based medicine: is there a conflict?\".","authors":"Michael Rie","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"57"},"PeriodicalIF":0.0,"publicationDate":"2007-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypertension: what it is; what it isn't; how to think about it, to prevent it, and to manage it. Interview by George D. Lundberg.","authors":"Suzanne Oparil","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"2007-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A reader responds to \"Tuberculosis and HIV-needed: a new paradigm for the control and management of linked epidemics\".","authors":"Chinwe Owunna","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74137,"journal":{"name":"MedGenMed : Medscape general medicine","volume":"9 4","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2007-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27296307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}