Bill Angelbeck, Chris Springer, Johnny Jones, Glyn Williams-Jones, Michael C. Wilson
Among Líĺwat people of the Interior Plateau of British Columbia, an oral tradition relays how early ancestors used to ascend Qẃelqẃelústen, or Mount Meager. The account maintains that those climbers could see the ocean, which is not the case today, because the mountain is surrounded by many other high peaks, and the Strait of Georgia is several mountain ridges to the west. However, the mountain is an active and volatile volcano, which last erupted circa 2360 cal BP. It is also the site of the largest landslide in Canadian history, which occurred in 2010. Given that it had been a high, glacier-capped mountain throughout the Holocene, much like other volcanoes along the coastal range, we surmise that a climber may have reasonably been afforded a view of the ocean from its prior heights. We conducted viewshed analyses of the potential mountain height prior to its eruption and determined that one could indeed view the ocean if the mountain were at least 950 m higher than it is today. This aligns with the oral tradition, indicating that it may be over 2,400 years old, and plausibly in the range of 4,000 to 9,000 years old when the mountain may have been at such a height.
{"title":"Líĺwat Climbers Could See the Ocean from the Peak of Qẃelqẃelústen: Evaluating Oral Traditions with Viewshed Analyses from the Mount Meager Volcanic Complex Prior to Its 2360 BP Eruption","authors":"Bill Angelbeck, Chris Springer, Johnny Jones, Glyn Williams-Jones, Michael C. Wilson","doi":"10.1017/aaq.2024.26","DOIUrl":"https://doi.org/10.1017/aaq.2024.26","url":null,"abstract":"<p>Among Líĺwat people of the Interior Plateau of British Columbia, an oral tradition relays how early ancestors used to ascend Qẃelqẃelústen, or Mount Meager. The account maintains that those climbers could see the ocean, which is not the case today, because the mountain is surrounded by many other high peaks, and the Strait of Georgia is several mountain ridges to the west. However, the mountain is an active and volatile volcano, which last erupted circa 2360 cal BP. It is also the site of the largest landslide in Canadian history, which occurred in 2010. Given that it had been a high, glacier-capped mountain throughout the Holocene, much like other volcanoes along the coastal range, we surmise that a climber may have reasonably been afforded a view of the ocean from its prior heights. We conducted viewshed analyses of the potential mountain height prior to its eruption and determined that one could indeed view the ocean if the mountain were at least 950 m higher than it is today. This aligns with the oral tradition, indicating that it may be over 2,400 years old, and plausibly in the range of 4,000 to 9,000 years old when the mountain may have been at such a height.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"19 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141085264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariane E. Thomas, Matthew E. Hill, Leah Stricker, Michael Lavin, David Givens, Alida de Flamingh, Kelsey E. Witt, Ripan S. Malhi, Andrew Kitchen
Multiple studies have demonstrated that European colonization of the Americas led to the death of nearly all North American dog mitochondrial lineages and replacement with European ones sometime between AD 1492 and the present day. Historical records indicate that colonists imported dogs from Europe to North America, where they became objects of interest and exchange as early as the seventeenth century. However, it is not clear whether the earliest archaeological dogs recovered from colonial contexts were of European, Indigenous, or mixed descent. To clarify the ancestry of dogs from the Jamestown Colony, Virginia, we sequenced ancient mitochondrial DNA from six archaeological dogs from the period 1609–1617. Our analysis shows that the Jamestown dogs have maternal lineages most closely associated with those of ancient Indigenous dogs of North America. Furthermore, these maternal lineages cluster with dogs from Late Woodland, Hopewell, and Virginia Algonquian archaeological sites. Our recovery of Indigenous dog lineages from a European colonial site suggests a complex social history of dogs at the interface of Indigenous and European populations during the early colonial period.
多项研究表明,从公元 1492 年至今,欧洲对美洲的殖民导致了几乎所有北美犬线粒体血统的消亡,取而代之的是欧洲犬线粒体血统。历史记录表明,殖民者将狗从欧洲进口到北美,早在十七世纪,狗就成为人们感兴趣和交流的对象。然而,目前还不清楚最早从殖民地考古发现的狗是欧洲人、土著人还是混血儿。为了弄清弗吉尼亚詹姆斯敦殖民地狗的祖先,我们对 1609-1617 年间的六只考古狗进行了古老的线粒体 DNA 测序。我们的分析表明,詹姆斯敦犬的母系与北美古代土著犬的母系关系最为密切。此外,这些母系与晚期林地、霍普韦尔和弗吉尼亚阿尔冈基亚考古遗址中的犬类聚集在一起。我们从一个欧洲殖民地遗址中发现的土著犬血统表明,在早期殖民地时期,犬在土著居民和欧洲居民之间有着复杂的社会历史。
{"title":"The Dogs of Tsenacomoco: Ancient DNA Reveals the Presence of Local Dogs at Jamestown Colony in the Early Seventeenth Century","authors":"Ariane E. Thomas, Matthew E. Hill, Leah Stricker, Michael Lavin, David Givens, Alida de Flamingh, Kelsey E. Witt, Ripan S. Malhi, Andrew Kitchen","doi":"10.1017/aaq.2024.25","DOIUrl":"https://doi.org/10.1017/aaq.2024.25","url":null,"abstract":"<p>Multiple studies have demonstrated that European colonization of the Americas led to the death of nearly all North American dog mitochondrial lineages and replacement with European ones sometime between AD 1492 and the present day. Historical records indicate that colonists imported dogs from Europe to North America, where they became objects of interest and exchange as early as the seventeenth century. However, it is not clear whether the earliest archaeological dogs recovered from colonial contexts were of European, Indigenous, or mixed descent. To clarify the ancestry of dogs from the Jamestown Colony, Virginia, we sequenced ancient mitochondrial DNA from six archaeological dogs from the period 1609–1617. Our analysis shows that the Jamestown dogs have maternal lineages most closely associated with those of ancient Indigenous dogs of North America. Furthermore, these maternal lineages cluster with dogs from Late Woodland, Hopewell, and Virginia Algonquian archaeological sites. Our recovery of Indigenous dog lineages from a European colonial site suggests a complex social history of dogs at the interface of Indigenous and European populations during the early colonial period.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"135 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141079349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Wichita and Affiliated Tribes have a long history of occupation in what is now known as Oklahoma. This includes evidence of habitations along Camp Creek and Sugar Creek near Anadarko in Caddo County. Here Wichita peoples camped, built grass houses and arbors, and held social gatherings leading up to and following the passing of the General Allotment Act in 1887. After allotment, communal camp and dance grounds were especially important focal points for community building. These places, such as the ichaskhah camp and dance ground discussed in this article, are critical to understanding the multigenerational connections between ancestral and living Wichita peoples. This history is also important to the community today. However, archaeological research of the Allotment period is exceptionally rare in this region. By using collaborative and Indigenous archaeological methodologies, this work documents the complexities of these places, challenging traditional assumptions of allotment-era cultural loss and assimilation.
{"title":"Anchoring Sovereignty in Space: Documenting Places of Wichita Community Building in the Twentieth Century","authors":"Brandi Bethke, Sarah Trabert, Gary McAdams","doi":"10.1017/aaq.2024.23","DOIUrl":"https://doi.org/10.1017/aaq.2024.23","url":null,"abstract":"<p>The Wichita and Affiliated Tribes have a long history of occupation in what is now known as Oklahoma. This includes evidence of habitations along Camp Creek and Sugar Creek near Anadarko in Caddo County. Here Wichita peoples camped, built grass houses and arbors, and held social gatherings leading up to and following the passing of the General Allotment Act in 1887. After allotment, communal camp and dance grounds were especially important focal points for community building. These places, such as the ichaskhah camp and dance ground discussed in this article, are critical to understanding the multigenerational connections between ancestral and living Wichita peoples. This history is also important to the community today. However, archaeological research of the Allotment period is exceptionally rare in this region. By using collaborative and Indigenous archaeological methodologies, this work documents the complexities of these places, challenging traditional assumptions of allotment-era cultural loss and assimilation.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"22 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
From the Archaic period onward, Indigenous populations across the Eastern Woodlands cultivated a suite of crops known to archaeologists as the Eastern Agricultural Complex. However, aside from squash (Cucurbita pepo) and sunflower (Helianthus annuus), little evidence exists for the cultivation of these plants in the northeastern Algonquian homeland. Botanical analysis from the Manna site (36Pi4), located in the Upper Delaware Valley, provides evidence for the cultivation of the full suite of Eastern Agricultural Complex crops. Flotation samples analyzed from Manna provide the first evidence for possible Lenape cultivation of chenopodium (Chenopodium berlandieri), squash, sunflower, and marshelder (Iva annua) from contexts dating to AD 0–1650 (Middle and Late Woodland) at Manna. Lenape cultivation of these crops complicates the traditional view of Indigenous agricultural systems in northeastern North America and raises questions about when and how these species were introduced to the region.
{"title":"Evidence for the Eastern Agricultural Complex Crops in the Upper Delaware Valley: Botanical Analysis from the Manna Site (36Pi4)","authors":"Justin M. Reamer","doi":"10.1017/aaq.2024.19","DOIUrl":"https://doi.org/10.1017/aaq.2024.19","url":null,"abstract":"<p>From the Archaic period onward, Indigenous populations across the Eastern Woodlands cultivated a suite of crops known to archaeologists as the Eastern Agricultural Complex. However, aside from squash (<span>Cucurbita pepo</span>) and sunflower (<span>Helianthus annuus</span>), little evidence exists for the cultivation of these plants in the northeastern Algonquian homeland. Botanical analysis from the Manna site (36Pi4), located in the Upper Delaware Valley, provides evidence for the cultivation of the full suite of Eastern Agricultural Complex crops. Flotation samples analyzed from Manna provide the first evidence for possible Lenape cultivation of chenopodium (<span>Chenopodium berlandieri</span>), squash, sunflower, and marshelder (<span>Iva annua</span>) from contexts dating to AD 0–1650 (Middle and Late Woodland) at Manna. Lenape cultivation of these crops complicates the traditional view of Indigenous agricultural systems in northeastern North America and raises questions about when and how these species were introduced to the region.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"10 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140895736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article presents a systematic literature review of publications from 2014 to 2021 using “archaeological site” and “climate change” as keywords, in addition to several terms representing forms of stakeholder engagement. Articles were thematically coded to explore trends at the intersection of climate change, archaeology, and local and Traditional stakeholders. Results show that nearly half of the selected publications did not include local and Traditional stakeholder engagement in studies related to climate adaptation planning for archaeological sites. Synthesis of the results with insights gained from other literature on decolonizing archaeology showed that potential reasons for this gap include (1) the academic publishing culture, (2) archaeology as a predominantly Western discipline, and (3) increasingly available tools for climate change adaptation planning for archaeological sites. This article calls on the academic community to consider holistic stewardship using a landscape approach and to use climate change adaptation planning to elevate local and Traditional stakeholder input and values.
{"title":"A Systematic Literature Review on Climate Change Adaptation Planning for Archaeological Site Management and the Prevalence of Stakeholder Engagement","authors":"Courtney Hotchkiss, Erin Seekamp","doi":"10.1017/aaq.2023.97","DOIUrl":"https://doi.org/10.1017/aaq.2023.97","url":null,"abstract":"<p>This article presents a systematic literature review of publications from 2014 to 2021 using “archaeological site” and “climate change” as keywords, in addition to several terms representing forms of stakeholder engagement. Articles were thematically coded to explore trends at the intersection of climate change, archaeology, and local and Traditional stakeholders. Results show that nearly half of the selected publications did not include local and Traditional stakeholder engagement in studies related to climate adaptation planning for archaeological sites. Synthesis of the results with insights gained from other literature on decolonizing archaeology showed that potential reasons for this gap include (1) the academic publishing culture, (2) archaeology as a predominantly Western discipline, and (3) increasingly available tools for climate change adaptation planning for archaeological sites. This article calls on the academic community to consider holistic stewardship using a landscape approach and to use climate change adaptation planning to elevate local and Traditional stakeholder input and values.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"9 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the Salish Sea region, labret adornment with lip plugs signify particular identities, and they are interpreted as emblematic of both membership in horizontal relationships and achieved status for traditional cultures associated with labret wearing on the Northwest Coast (NWC) of North America. Labrets are part of a shared symbolic language in the region, one that we argue facilitated access to beneficial horizontal relationships (e.g., Angelbeck and Grier 2012; Rorabaugh and Shantry 2017). We employ social network analysis (SNA) to examine labrets from 31 dated site components in the Salish Sea region spanning between 3500 and 1500 cal BP. Following this period, the more widely distributed practice of cranial modification as a social marker of status developed in the region. The SNA of labret data shows an elaboration and expansion of antecedent social networks prior to the practice of cranial modification. Understandings of status on the NWC work backward from direct contact with Indigenous societies. Labret wearing begins at the Middle-Late Holocene transition, setting an earlier stage for the horizontal social relationships seen in the ethnohistoric period. These findings are consistent with the practice as signifying restricted group membership based on affinal ties and achieved social status.
{"title":"A Social Network Analysis of Traditional Labrets and Horizontal Relationships in the Salish Sea Region of Northwestern North America","authors":"Adam N. Rorabaugh, Kate A. Shantry","doi":"10.1017/aaq.2023.98","DOIUrl":"https://doi.org/10.1017/aaq.2023.98","url":null,"abstract":"<p>In the Salish Sea region, labret adornment with lip plugs signify particular identities, and they are interpreted as emblematic of both membership in horizontal relationships and achieved status for traditional cultures associated with labret wearing on the Northwest Coast (NWC) of North America. Labrets are part of a shared symbolic language in the region, one that we argue facilitated access to beneficial horizontal relationships (e.g., Angelbeck and Grier 2012; Rorabaugh and Shantry 2017). We employ social network analysis (SNA) to examine labrets from 31 dated site components in the Salish Sea region spanning between 3500 and 1500 cal BP. Following this period, the more widely distributed practice of cranial modification as a social marker of status developed in the region. The SNA of labret data shows an elaboration and expansion of antecedent social networks prior to the practice of cranial modification. Understandings of status on the NWC work backward from direct contact with Indigenous societies. Labret wearing begins at the Middle-Late Holocene transition, setting an earlier stage for the horizontal social relationships seen in the ethnohistoric period. These findings are consistent with the practice as signifying restricted group membership based on affinal ties and achieved social status.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"12 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna K. Gilmore, Ajani Ade Ofunniyin, La'Sheia O. Oubré, Raquel E. Fleskes, Theodore G. Schurr
In 2013, 36 Ancestors of African descent were identified in an unmarked eighteenth-century burial ground during construction in Charleston, South Carolina. The site, later referred to as the Anson Street African Burial Ground, was buried beneath the growing city and forgotten in the centuries that followed. The ethical treatment of these ancestral remains was of paramount importance to our community. Historically, narratives relating to the lives of African descendant people in Charleston have been inadequately documented and shared. For these reasons, we engaged the local African American community in a multifaceted memorialization process. Together, we sought to sensitively ensure that the Ancestors’ identities and lives were fully explored according to the collective descendant community's wishes. To this end, we involved the community in researching and celebrating the Ancestors’ lives through arts and education programs and analyzed their and community members’ DNA to elucidate their ancestry. Our engagement initiatives increased access for all ages to archaeological, historical, and genetic research and encouraged active participation in the design of a permanent memorial. The Anson Street African Burial Ground Project provides a successful example of community-engaged activist archaeology focused on honoring the Ancestors and their descendants.
2013 年,在南卡罗来纳州查尔斯顿施工期间,在一处无标记的十八世纪墓地中发现了 36 位非洲裔祖先。该墓地后来被称为 "安森街非洲人墓地"(Anson Street African Burial Ground),被埋葬在不断发展的城市之下,并在之后的几个世纪里被人们遗忘。如何合乎道德地处理这些祖先的遗骸对我们的社区至关重要。从历史上看,有关查尔斯顿非洲后裔生活的叙述没有得到充分的记录和分享。出于这些原因,我们让当地的非洲裔美国人社区参与到多方面的纪念过程中。我们力求共同确保按照后裔社区的集体意愿,对先祖的身份和生活进行充分探讨。为此,我们通过艺术和教育计划让社区参与研究和庆祝先祖的生活,并分析他们和社区成员的 DNA 以阐明他们的祖先。我们的参与举措让所有年龄段的人都有更多机会接触考古、历史和基因研究,并鼓励他们积极参与永久纪念碑的设计。安森街非洲人墓地项目为社区参与的积极考古学提供了一个成功范例,其重点是纪念祖先及其后裔。
{"title":"“The Dead Have Been Awakened in the Service of the Living”: Activist Community-Engaged Archaeology in Charleston, South Carolina","authors":"Joanna K. Gilmore, Ajani Ade Ofunniyin, La'Sheia O. Oubré, Raquel E. Fleskes, Theodore G. Schurr","doi":"10.1017/aaq.2023.105","DOIUrl":"https://doi.org/10.1017/aaq.2023.105","url":null,"abstract":"<p>In 2013, 36 Ancestors of African descent were identified in an unmarked eighteenth-century burial ground during construction in Charleston, South Carolina. The site, later referred to as the Anson Street African Burial Ground, was buried beneath the growing city and forgotten in the centuries that followed. The ethical treatment of these ancestral remains was of paramount importance to our community. Historically, narratives relating to the lives of African descendant people in Charleston have been inadequately documented and shared. For these reasons, we engaged the local African American community in a multifaceted memorialization process. Together, we sought to sensitively ensure that the Ancestors’ identities and lives were fully explored according to the collective descendant community's wishes. To this end, we involved the community in researching and celebrating the Ancestors’ lives through arts and education programs and analyzed their and community members’ DNA to elucidate their ancestry. Our engagement initiatives increased access for all ages to archaeological, historical, and genetic research and encouraged active participation in the design of a permanent memorial. The Anson Street African Burial Ground Project provides a successful example of community-engaged activist archaeology focused on honoring the Ancestors and their descendants.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"61 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
At the turn of the twentieth century, American logging companies backed by the US colonial regime initiated extensive extraction in Bikol, Philippines. Industrial infrastructure and the involvement of a newly assembled Bikolano workforce left a profound imprint on the region's landscape. This article discusses a collaborative archaeological project that used archival materials, place-name analysis, ethnographic interviews, discussions with local scholars, satellite mapping, and drone-mounted lidar scans of former industrial sites. Findings shed light on the enduring ramifications of American logging in the early 1900s on settlement patterns, the infrastructure of routes and mobility, the state of industries from Philippine independence in 1946 through the 1980s, and ongoing environmental hazards. These findings emphasize the legacy of American empire, reveal the role of Filipino logging workers in shaping the landscape through settlement decisions, and uncover intricate connections across a pan-Pacific American colonial frontier that was shaped by both extractive and settler colonialism. This article adds to an emerging trend in Americanist archaeology in which archaeology investigates recent historical and even contemporary events.
{"title":"Manifest Destiny in Southeast Asia: Archaeology of American Colonial Industry in the Philippines, 1898–1987","authors":"Robin Meyer-Lorey, Stephen Acabado","doi":"10.1017/aaq.2024.24","DOIUrl":"https://doi.org/10.1017/aaq.2024.24","url":null,"abstract":"<p>At the turn of the twentieth century, American logging companies backed by the US colonial regime initiated extensive extraction in Bikol, Philippines. Industrial infrastructure and the involvement of a newly assembled Bikolano workforce left a profound imprint on the region's landscape. This article discusses a collaborative archaeological project that used archival materials, place-name analysis, ethnographic interviews, discussions with local scholars, satellite mapping, and drone-mounted lidar scans of former industrial sites. Findings shed light on the enduring ramifications of American logging in the early 1900s on settlement patterns, the infrastructure of routes and mobility, the state of industries from Philippine independence in 1946 through the 1980s, and ongoing environmental hazards. These findings emphasize the legacy of American empire, reveal the role of Filipino logging workers in shaping the landscape through settlement decisions, and uncover intricate connections across a pan-Pacific American colonial frontier that was shaped by both extractive and settler colonialism. This article adds to an emerging trend in Americanist archaeology in which archaeology investigates recent historical and even contemporary events.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"4 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-02DOI: 10.1101/2022.05.29.493897
Shreya Bhattacharya, Nicholas Ristic, Avi J Cohen, Derek Tsang, Meredith Gwin, Rebecca Howell, Grant Young, Eric Jung, Charles S Dela Cruz, Samir Gautam
Acute respiratory distress syndrome (ARDS) is a life-threatening clinical condition defined by rapid-onset respiratory failure following acute lung injury (ALI). The high mortality rate and rising incidence of ARDS due to COVID-19 make it an important research priority. Here we sought to investigate the role of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) in ARDS. CRTH2 is a G protein-coupled receptor best studied in the context of type 2 immunity, but it also exerts effects on neutrophilic inflammation. To evaluate its role in mouse models of ARDS, we first examined its expression pattern on murine neutrophils. We found it is expressed on neutrophils, but only after extravasation into the lung. Next, we showed that CRTH2 expression on extravasated lung neutrophils promotes cell survival, as genetic deletion of CRTH2 and pharmacologic inhibition of CRTH2 using fevipiprant both led to increased apoptosis in vitro. We then evaluated the role of CRTH2 in vivo using a murine model of LPS-induced ALI. In line with the pro-inflammatory effects of CRTH2 in vitro, we observed improvement of lung injury in CRTH2-deficient mice in terms of vascular leak, weight loss and survival after LPS administration. However, neutrophilic inflammation was elevated, not suppressed in the CRTH2 KO. This finding indicated a second mechanism offsetting the pro-survival effect of CRTH2 on neutrophils. Bulk RNAseq of lung tissue indicated impairments in type 2 immune signaling in the CRTH2 KO, and qPCR and ELISA confirmed downregulation of IL-4, which is known to suppress neutrophilic inflammation. Thus, CRTH2 may play a dual role in ALI, directly promoting neutrophil cell survival, but indirectly suppressing neutrophil effector function via IL-4.
{"title":"A dual role for CRTH2 in acute lung injury.","authors":"Shreya Bhattacharya, Nicholas Ristic, Avi J Cohen, Derek Tsang, Meredith Gwin, Rebecca Howell, Grant Young, Eric Jung, Charles S Dela Cruz, Samir Gautam","doi":"10.1101/2022.05.29.493897","DOIUrl":"10.1101/2022.05.29.493897","url":null,"abstract":"<p><p>Acute respiratory distress syndrome (ARDS) is a life-threatening clinical condition defined by rapid-onset respiratory failure following acute lung injury (ALI). The high mortality rate and rising incidence of ARDS due to COVID-19 make it an important research priority. Here we sought to investigate the role of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) in ARDS. CRTH2 is a G protein-coupled receptor best studied in the context of type 2 immunity, but it also exerts effects on neutrophilic inflammation. To evaluate its role in mouse models of ARDS, we first examined its expression pattern on murine neutrophils. We found it is expressed on neutrophils, but only after extravasation into the lung. Next, we showed that CRTH2 expression on extravasated lung neutrophils promotes cell survival, as genetic deletion of CRTH2 and pharmacologic inhibition of CRTH2 using fevipiprant both led to increased apoptosis in vitro. We then evaluated the role of CRTH2 in vivo using a murine model of LPS-induced ALI. In line with the pro-inflammatory effects of CRTH2 in vitro, we observed improvement of lung injury in CRTH2-deficient mice in terms of vascular leak, weight loss and survival after LPS administration. However, neutrophilic inflammation was elevated, not suppressed in the CRTH2 KO. This finding indicated a second mechanism offsetting the pro-survival effect of CRTH2 on neutrophils. Bulk RNAseq of lung tissue indicated impairments in type 2 immune signaling in the CRTH2 KO, and qPCR and ELISA confirmed downregulation of IL-4, which is known to suppress neutrophilic inflammation. Thus, CRTH2 may play a dual role in ALI, directly promoting neutrophil cell survival, but indirectly suppressing neutrophil effector function via IL-4.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90609136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2023-07-20DOI: 10.1177/21677026231184890
Simon B Goldberg, Zishan Jiwani, Daniel M Bolt, Kevin M Riordan, Richard J Davidson, Matthew J Hirshberg
Bidirectional associations between changes in symptoms and alliance are established for in-person psychotherapy. Alliance may play an important role in promoting engagement and effectiveness within unguided mobile health (mHealth) interventions. Using models disaggregating alliance and psychological distress into within- and between-person components (random intercept cross-lagged panel model), we report bidirectional associations between alliance and distress over the course of a 4-week smartphone-based meditation intervention (n=302, 80.0% elevated depression/anxiety). Associations were stable across time with effect sizes similar to those observed for psychotherapy (βs=-.13 to -.14 and -.09 to -.10, for distress to alliance and alliance to distress, respectively). Alliance may be worth measuring to improve the acceptability and effectiveness of mHealth tools. Further empirical and theoretical work characterizing the role and meaning of alliance in unguided mHealth is warranted.
{"title":"Evidence for Bidirectional, Cross-Lagged Associations Between Alliance and Psychological Distress in an Unguided Mobile-Health Intervention.","authors":"Simon B Goldberg, Zishan Jiwani, Daniel M Bolt, Kevin M Riordan, Richard J Davidson, Matthew J Hirshberg","doi":"10.1177/21677026231184890","DOIUrl":"10.1177/21677026231184890","url":null,"abstract":"<p><p>Bidirectional associations between changes in symptoms and alliance are established for in-person psychotherapy. Alliance may play an important role in promoting engagement and effectiveness within unguided mobile health (mHealth) interventions. Using models disaggregating alliance and psychological distress into within- and between-person components (random intercept cross-lagged panel model), we report bidirectional associations between alliance and distress over the course of a 4-week smartphone-based meditation intervention (<i>n</i>=302, 80.0% elevated depression/anxiety). Associations were stable across time with effect sizes similar to those observed for psychotherapy (βs=-.13 to -.14 and -.09 to -.10, for distress to alliance and alliance to distress, respectively). Alliance may be worth measuring to improve the acceptability and effectiveness of mHealth tools. Further empirical and theoretical work characterizing the role and meaning of alliance in unguided mHealth is warranted.</p>","PeriodicalId":7424,"journal":{"name":"American Antiquity","volume":"31 1","pages":"517-525"},"PeriodicalIF":4.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11164554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90784919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}